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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZNF333

Z-value: 2.40

Motif logo

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Transcription factors associated with ZNF333

Gene Symbol Gene ID Gene Info
ZNF333
ENSG00000160961.7 zinc finger protein 333

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_14793991_14794142ZNF33366450.148571-0.636.8e-02Click!
chr19_14801111_14801506ZNF3333950.514246-0.491.8e-01Click!
chr19_14800223_14800431ZNF3333840.555379-0.442.4e-01Click!
chr19_14800609_14800883ZNF333350.558616-0.393.0e-01Click!

Activity of the ZNF333 motif across conditions

Conditions sorted by the z-value of the ZNF333 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr22_40301249_40301400 0.66 GRAP2
 GRB2-related adaptor protein 2
 4211
 0.2
chr1_84612029_84612357 0.60 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
 2239
 0.42
chr7_38312198_38312349 0.58 STARD3NL
 STARD3 N-terminal like
 94276
 0.09
chr10_17705373_17705524 0.53 ENSG00000251959
 .
 15739
 0.14
chr10_25176560_25176711 0.52 ENSG00000240294
 .
 21106
 0.23
chr8_93110125_93110276 0.51 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 1684
 0.54
chr11_118210860_118211247 0.51 CD3D
 CD3d molecule, delta (CD3-TCR complex)
 599
 0.61
chr8_58961464_58961615 0.50 FAM110B
 family with sequence similarity 110, member B
 54426
 0.18
chrX_135730916_135731129 0.50 CD40LG
 CD40 ligand
 636
 0.7
chr7_142511951_142512102 0.48 PRSS3P2
 protease, serine, 3 pseudogene 2
 30895
 0.13
chr5_109028785_109028975 0.47 MAN2A1
 mannosidase, alpha, class 2A, member 1
 3813
 0.23
chr12_21606326_21606605 0.46 PYROXD1
 pyridine nucleotide-disulphide oxidoreductase domain 1
 15616
 0.17
chr14_61802494_61802645 0.46 PRKCH
 protein kinase C, eta
 8391
 0.2
chr5_158520160_158520311 0.45 EBF1
 early B-cell factor 1
 6466
 0.27
chr3_86894495_86894646 0.45 VGLL3
 vestigial like 3 (Drosophila)
 145282
 0.05
chr6_90790442_90790643 0.45 ENSG00000222078
 .
 79317
 0.1
chr2_204734743_204734894 0.44 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 137
 0.97
chr4_143321559_143321710 0.44 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 30778
 0.27
chr7_38400564_38400715 0.43 AMPH
 amphiphysin
 102074
 0.08
chr14_100531999_100532513 0.42 EVL
 Enah/Vasp-like
 498
 0.76
chr3_186743627_186743921 0.41 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 503
 0.85
chr1_160489868_160490211 0.41 SLAMF6
 SLAM family member 6
 2993
 0.18
chr1_207093221_207093431 0.41 FAIM3
 Fas apoptotic inhibitory molecule 3
 1886
 0.27
chr13_50028881_50029032 0.41 AL136218.1
 Sarcoma antigen NY-SAR-79; Uncharacterized protein
 8402
 0.17
chr14_55769874_55770025 0.40 FBXO34
 F-box protein 34
 31077
 0.17
chr11_118176160_118176414 0.40 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
 673
 0.59
chr6_90791046_90791197 0.40 ENSG00000222078
 .
 79896
 0.1
chr11_97853847_97853998 0.40 ENSG00000216073
 .
 70033
 0.14
chr13_99955816_99955967 0.40 GPR183
 G protein-coupled receptor 183
 3768
 0.25
chr5_159897818_159898005 0.40 ENSG00000265237
 .
 3498
 0.21
chr4_109086470_109087224 0.40 LEF1
 lymphoid enhancer-binding factor 1
 610
 0.72
chr14_99702706_99702901 0.40 AL109767.1
26482
 0.19
chr9_33162104_33162255 0.40 RP11-326F20.5
4794
 0.16
chr5_85693756_85693907 0.39 NBPF22P
 neuroblastoma breakpoint family, member 22, pseudogene
 115247
 0.07
chr4_20289069_20289220 0.38 SLIT2
 slit homolog 2 (Drosophila)
 32601
 0.24
chr1_207092040_207092191 0.38 FAIM3
 Fas apoptotic inhibitory molecule 3
 3097
 0.19
chr13_99909728_99909879 0.38 GPR18
 G protein-coupled receptor 18
 825
 0.64
chr8_82051121_82051272 0.38 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 26893
 0.24
chr1_111212431_111212582 0.37 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 5149
 0.2
chr7_107386589_107386740 0.37 AC002467.7
1638
 0.29
chr4_83930221_83930372 0.37 LIN54
 lin-54 homolog (C. elegans)
 1566
 0.33
chr22_20905629_20905785 0.37 MED15
 mediator complex subunit 15
 130
 0.95
chr14_22955963_22956254 0.37 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 63
 0.95
chr19_2892956_2893107 0.37 ZNF57
 zinc finger protein 57
 7865
 0.11
chr12_92440588_92440837 0.37 C12orf79
 chromosome 12 open reading frame 79
 90085
 0.08
chrX_110366293_110366528 0.37 PAK3
 p21 protein (Cdc42/Rac)-activated kinase 3
 105
 0.98
chr10_33239572_33239908 0.36 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 4851
 0.32
chrX_103515232_103515731 0.36 ESX1
 ESX homeobox 1
 15867
 0.25
chr1_193319454_193319605 0.36 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 163745
 0.04
chr5_19885020_19885171 0.36 CDH18
 cadherin 18, type 2
 1286
 0.64
chr10_69231096_69231247 0.36 CTNNA3
 catenin (cadherin-associated protein), alpha 3
 176100
 0.03
chr7_38392814_38392965 0.36 AMPH
 amphiphysin
 109824
 0.07
chr13_99949671_99949957 0.35 GPR183
 G protein-coupled receptor 183
 9845
 0.2
chr3_68107536_68107743 0.35 FAM19A1
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
 52266
 0.19
chr11_94802718_94802918 0.35 ENDOD1
 endonuclease domain containing 1
 20156
 0.19
chr21_32558355_32558506 0.35 TIAM1
 T-cell lymphoma invasion and metastasis 1
 55891
 0.16
chr2_177679359_177679510 0.35 ENSG00000206866
 .
 115384
 0.06
chr2_235401897_235402222 0.35 ARL4C
 ADP-ribosylation factor-like 4C
 3185
 0.41
chr3_150686052_150686203 0.35 CLRN1-AS1
 CLRN1 antisense RNA 1
 4338
 0.2
chr7_28741672_28741823 0.34 CREB5
 cAMP responsive element binding protein 5
 16149
 0.3
chr3_12332222_12332373 0.34 PPARG
 peroxisome proliferator-activated receptor gamma
 1727
 0.49
chr1_86848612_86848888 0.34 ODF2L
 outer dense fiber of sperm tails 2-like
 129
 0.97
chr2_237077720_237077871 0.34 GBX2
 gastrulation brain homeobox 2
 783
 0.52
chr5_74347596_74347880 0.34 GCNT4
 glucosaminyl (N-acetyl) transferase 4, core 2
 21014
 0.25
chr2_181995547_181995698 0.34 UBE2E3
 ubiquitin-conjugating enzyme E2E 3
 148872
 0.04
chr3_195806787_195806938 0.34 TFRC
 transferrin receptor
 2099
 0.29
chr21_19166563_19166714 0.33 AL109761.5
833
 0.67
chr12_47607489_47607701 0.33 PCED1B
 PC-esterase domain containing 1B
 2457
 0.32
chr14_41685035_41685186 0.33 ENSG00000221695
 .
 133387
 0.06
chr3_158393631_158393782 0.33 LXN
 latexin
 3224
 0.22
chr11_129716903_129717070 0.33 TMEM45B
 transmembrane protein 45B
 3241
 0.32
chr9_14180845_14181011 0.33 NFIB
 nuclear factor I/B
 131
 0.98
chr1_209998785_209998936 0.33 DIEXF
 digestive organ expansion factor homolog (zebrafish)
 2492
 0.24
chr11_128378341_128378619 0.33 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 3191
 0.31
chr13_31348514_31348665 0.33 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 38944
 0.19
chrX_57931578_57932092 0.33 ZXDA
 zinc finger, X-linked, duplicated A
 5232
 0.36
chr2_136876365_136876597 0.33 CXCR4
 chemokine (C-X-C motif) receptor 4
 746
 0.77
chr19_42056193_42056486 0.33 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 453
 0.8
chr22_40297106_40297391 0.32 GRAP2
 GRB2-related adaptor protein 2
 135
 0.96
chr11_57494574_57494725 0.32 C11orf31
 chromosome 11 open reading frame 31
 14176
 0.1
chr5_39197523_39197702 0.32 FYB
 FYN binding protein
 5517
 0.3
chr14_41187793_41187944 0.32 ENSG00000221695
 .
 630629
 0.0
chr13_99953472_99953749 0.32 GPR183
 G protein-coupled receptor 183
 6049
 0.22
chr2_204801338_204802214 0.32 ICOS
 inducible T-cell co-stimulator
 273
 0.95
chr3_151936530_151936714 0.32 MBNL1
 muscleblind-like splicing regulator 1
 49207
 0.15
chr12_46603502_46603653 0.32 SLC38A1
 solute carrier family 38, member 1
 57907
 0.16
chr6_63090511_63090662 0.32 KHDRBS2
 KH domain containing, RNA binding, signal transduction associated 2
 94454
 0.1
chr18_74837172_74837323 0.32 MBP
 myelin basic protein
 2421
 0.42
chr12_56329135_56329873 0.32 DGKA
 diacylglycerol kinase, alpha 80kDa
 114
 0.92
chr1_117302165_117302316 0.32 CD2
 CD2 molecule
 5151
 0.24
chr2_197047793_197047944 0.32 STK17B
 serine/threonine kinase 17b
 6641
 0.2
chr6_128229281_128229524 0.32 THEMIS
 thymocyte selection associated
 7176
 0.3
chr1_101705180_101705331 0.31 S1PR1
 sphingosine-1-phosphate receptor 1
 2811
 0.2
chr6_143178538_143178701 0.31 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 20435
 0.26
chr3_128207705_128209147 0.31 RP11-475N22.4
326
 0.79
chr2_208108634_208108785 0.31 AC007879.5
10267
 0.22
chr10_62487366_62487517 0.31 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 5807
 0.3
chr17_56654648_56654799 0.31 C17orf47
 chromosome 17 open reading frame 47
 32994
 0.1
chr1_246812163_246812314 0.31 RP11-439E19.1
43063
 0.14
chr7_130632583_130632734 0.31 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 36210
 0.19
chr5_156608214_156608444 0.31 ITK
 IL2-inducible T-cell kinase
 492
 0.72
chr8_97350508_97350718 0.31 ENSG00000199732
 .
 29063
 0.17
chr3_50644588_50644940 0.31 CISH
 cytokine inducible SH2-containing protein
 4439
 0.16
chr7_103577846_103577997 0.31 RELN
 reelin
 52042
 0.18
chr4_16877414_16877627 0.31 LDB2
 LIM domain binding 2
 22665
 0.29
chr12_55374952_55375103 0.31 TESPA1
 thymocyte expressed, positive selection associated 1
 595
 0.79
chr4_40209794_40209945 0.31 RHOH
 ras homolog family member H
 7905
 0.22
chr6_122931066_122932065 0.30 PKIB
 protein kinase (cAMP-dependent, catalytic) inhibitor beta
 188
 0.97
chr7_150146102_150146542 0.30 GIMAP8
 GTPase, IMAP family member 8
 1396
 0.39
chr17_266453_266873 0.30 AC108004.3
2849
 0.2
chr5_39186524_39186686 0.30 FYB
 FYN binding protein
 16524
 0.26
chr13_99958437_99958588 0.30 GPR183
 G protein-coupled receptor 183
 1147
 0.52
chr16_60708046_60708197 0.30 ENSG00000265127
 .
 95762
 0.1
chr12_72523140_72523291 0.30 RP11-89M22.3
72058
 0.12
chr2_200470649_200470800 0.30 SATB2
 SATB homeobox 2
 134735
 0.05
chr6_89584193_89584392 0.30 RNGTT
 RNA guanylyltransferase and 5'-phosphatase
 88988
 0.08
chr20_43347005_43347156 0.30 WISP2
 WNT1 inducible signaling pathway protein 2
 3194
 0.18
chr3_87484012_87484163 0.30 POU1F1
 POU class 1 homeobox 1
 158350
 0.04
chr20_51591815_51591966 0.30 TSHZ2
 teashirt zinc finger homeobox 2
 2944
 0.37
chr7_15730839_15730990 0.30 MEOX2
 mesenchyme homeobox 2
 4477
 0.29
chr19_6926549_6926700 0.30 RP11-1137G4.3
26598
 0.12
chr17_77001373_77001524 0.29 CANT1
 calcium activated nucleotidase 1
 4364
 0.16
chr12_12712693_12713134 0.29 DUSP16
 dual specificity phosphatase 16
 1098
 0.58
chr1_12445934_12446085 0.29 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 23915
 0.22
chr6_65662806_65662957 0.29 ENSG00000221312
 .
 21405
 0.3
chr21_21342429_21342580 0.29 ENSG00000251851
 .
 385660
 0.01
chr11_120195755_120196855 0.29 TMEM136
 transmembrane protein 136
 289
 0.9
chr3_98280847_98280998 0.29 GPR15
 G protein-coupled receptor 15
 30179
 0.12
chr11_46581548_46581763 0.29 AMBRA1
 autophagy/beclin-1 regulator 1
 31259
 0.15
chr5_64310480_64310631 0.29 ENSG00000207439
 .
 108641
 0.07
chr20_55204347_55205219 0.29 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 425
 0.81
chr7_114566372_114566651 0.29 MDFIC
 MyoD family inhibitor domain containing
 3380
 0.39
chr4_66185713_66185864 0.29 EPHA5
 EPH receptor A5
 349865
 0.01
chr2_237446083_237446280 0.28 IQCA1
 IQ motif containing with AAA domain 1
 29996
 0.19
chr14_22322504_22322655 0.28 ENSG00000222776
 .
 73794
 0.11
chr6_43351299_43351450 0.28 ZNF318
 zinc finger protein 318
 14193
 0.14
chr12_119615001_119615152 0.28 RP11-64B16.3
787
 0.51
chr4_24732106_24732257 0.28 SOD3
 superoxide dismutase 3, extracellular
 59353
 0.15
chr14_99735608_99735969 0.28 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
 1777
 0.38
chr8_56777196_56777347 0.28 LYN
 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
 15101
 0.15
chr14_61790070_61790226 0.28 ENSG00000247287
 .
 612
 0.51
chr10_14920855_14921866 0.28 SUV39H2
 suppressor of variegation 3-9 homolog 2 (Drosophila)
 439
 0.82
chr4_40210765_40210916 0.28 RHOH
 ras homolog family member H
 8876
 0.22
chr4_154410997_154411265 0.28 KIAA0922
 KIAA0922
 23630
 0.22
chr3_66940641_66940792 0.28 KBTBD8
 kelch repeat and BTB (POZ) domain containing 8
 108011
 0.08
chr7_19139525_19139676 0.28 AC003986.6
12497
 0.16
chr12_40448353_40448504 0.28 SLC2A13
 solute carrier family 2 (facilitated glucose transporter), member 13
 51233
 0.17
chr6_119398487_119399078 0.28 FAM184A
 family with sequence similarity 184, member A
 755
 0.67
chr2_196444875_196445026 0.28 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 4249
 0.31
chr1_195164944_195165095 0.28 ENSG00000265108
 .
 69208
 0.15
chr2_181570738_181570889 0.28 ENSG00000264976
 .
 88880
 0.1
chr1_51171312_51171463 0.28 ENSG00000252825
 .
 44581
 0.17
chr3_130176422_130176573 0.28 COL6A5
 collagen, type VI, alpha 5
 14169
 0.26
chr5_130590704_130590855 0.28 CDC42SE2
 CDC42 small effector 2
 8923
 0.28
chr18_67623543_67623764 0.28 CD226
 CD226 molecule
 253
 0.95
chr12_13348835_13349296 0.27 EMP1
 epithelial membrane protein 1
 585
 0.82
chr9_74429580_74429731 0.27 TMEM2
 transmembrane protein 2
 1951
 0.44
chr2_216650848_216650999 0.27 ENSG00000212055
 .
 92719
 0.09
chr5_35854839_35855004 0.27 IL7R
 interleukin 7 receptor
 1476
 0.43
chr12_94805998_94806149 0.27 CCDC41
 coiled-coil domain containing 41
 47649
 0.14
chr3_24640431_24640582 0.27 ENSG00000265028
 .
 77580
 0.1
chr2_144006550_144006740 0.27 RP11-190J23.1
76904
 0.11
chrX_77039434_77039643 0.27 ATRX
 alpha thalassemia/mental retardation syndrome X-linked
 2164
 0.37
chr5_66833336_66833975 0.27 ENSG00000222939
 .
 73219
 0.13
chr11_88087230_88087381 0.27 CTSC
 cathepsin C
 16350
 0.28
chr3_156535655_156535806 0.27 LEKR1
 leucine, glutamate and lysine rich 1
 8359
 0.29
chr3_63954713_63955178 0.27 ATXN7
 ataxin 7
 1525
 0.34
chr4_109404487_109404709 0.27 ENSG00000266046
 .
 93698
 0.08
chr9_3477118_3477287 0.27 AL365202.1
 Uncharacterized protein
 8021
 0.25
chr13_50650646_50650797 0.27 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
 5586
 0.18
chr14_98442707_98443118 0.27 C14orf64
 chromosome 14 open reading frame 64
 1471
 0.59
chr5_39201497_39202174 0.27 FYB
 FYN binding protein
 1294
 0.59
chr3_37214088_37214239 0.27 LRRFIP2
 leucine rich repeat (in FLII) interacting protein 2
 1892
 0.27
chr10_6625751_6625936 0.27 PRKCQ
 protein kinase C, theta
 3580
 0.38
chr1_207483654_207483805 0.26 CD55
 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
 11124
 0.27
chr5_72570204_72570355 0.26 TMEM174
 transmembrane protein 174
 101257
 0.06
chr9_112674232_112674383 0.26 PALM2
 paralemmin 2
 44996
 0.18
chr2_38826937_38827218 0.26 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 91
 0.96
chr2_160291322_160291473 0.26 BAZ2B
 bromodomain adjacent to zinc finger domain, 2B
 1936
 0.41
chr14_52688265_52688453 0.26 PTGDR
 prostaglandin D2 receptor (DP)
 46072
 0.17
chr15_38852890_38853244 0.26 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 587
 0.75
chr14_65086017_65086168 0.26 RP11-973N13.3
22838
 0.16
chr19_42057151_42057302 0.26 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 1340
 0.4
chr1_161903850_161904001 0.26 OLFML2B
 olfactomedin-like 2B
 51097
 0.14
chr14_55541755_55541906 0.26 MAPK1IP1L
 mitogen-activated protein kinase 1 interacting protein 1-like
 23481
 0.17
chr7_47333703_47333854 0.26 TNS3
 tensin 3
 13862
 0.31
chr2_234934004_234934210 0.26 SPP2
 secreted phosphoprotein 2, 24kDa
 25216
 0.2
chr3_99928980_99929378 0.26 ENSG00000238377
 .
 11257
 0.16
chr10_95172691_95172842 0.26 MYOF
 myoferlin
 69185
 0.1
chr2_204733780_204733985 0.26 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 1073
 0.62
chr14_106327816_106327967 0.26 IGHJ6
 immunoglobulin heavy joining 6
 1577
 0.06
chr4_125862018_125862169 0.26 ANKRD50
 ankyrin repeat domain 50
 228206
 0.02
chr4_148774792_148774943 0.26 ARHGAP10
 Rho GTPase activating protein 10
 28151
 0.19
chr1_81943750_81943901 0.26 RP5-837I24.6
26959
 0.24
chr21_32567568_32567719 0.26 TIAM1
 T-cell lymphoma invasion and metastasis 1
 65104
 0.13
chr15_66681568_66681719 0.26 MAP2K1
 mitogen-activated protein kinase kinase 1
 2488
 0.18
chr9_130740055_130740787 0.26 FAM102A
 family with sequence similarity 102, member A
 2371
 0.18
chr7_86847208_86847359 0.26 ENSG00000200397
 .
 745
 0.59
chr9_802061_802237 0.26 DMRT1
 doublesex and mab-3 related transcription factor 1
 39541
 0.18
chr17_53314641_53314792 0.26 HLF
 hepatic leukemia factor
 27657
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF333

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2 0.8 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 0.4 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.2 0.5 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.2 0.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.6 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.5 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.5 GO:1904019 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1 0.4 GO:0002669 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.3 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.3 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.1 0.3 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.1 0.3 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.4 GO:0002855 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 1.1 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.4 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.1 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.2 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.1 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0034393 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 2.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0032816 positive regulation of natural killer cell activation(GO:0032816)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.2 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.0 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.1 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:1904748 regulation of apoptotic process involved in morphogenesis(GO:1902337) regulation of apoptotic process involved in development(GO:1904748)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0071875 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0060044 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.2 GO:0060421 positive regulation of heart growth(GO:0060421)
0.0 0.1 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.1 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.1 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.0 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.0 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.0 GO:1901722 regulation of cell proliferation involved in kidney development(GO:1901722)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0007625 grooming behavior(GO:0007625)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.0 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.0 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.0 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0045606 positive regulation of epidermal cell differentiation(GO:0045606)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0006949 syncytium formation(GO:0006949)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.2 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.0 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0061046 regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0006273 lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.0 GO:0072217 negative regulation of metanephros development(GO:0072217)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0031904 endosome lumen(GO:0031904)
0.1 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0043230 extracellular organelle(GO:0043230)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.0 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0045178 basal part of cell(GO:0045178)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0016151 nickel cation binding(GO:0016151)
0.1 1.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.5 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0045502 dynein binding(GO:0045502)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.0 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 1.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport