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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF350

Z-value: 0.80

Motif logo

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 ZNF350

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ZNF350chr19_52490149_524904171740.918947-0.571.1e-01Click!
ZNF350chr19_52476505_5247665615260.2788310.432.4e-01Click!
ZNF350chr19_52472408_5247255956230.1302340.353.6e-01Click!
ZNF350chr19_52468615_5246876694160.1181120.343.8e-01Click!
ZNF350chr19_52497579_5249773075450.1205500.314.1e-01Click!

Activity of the ZNF350 motif across conditions

Conditions sorted by the z-value of the ZNF350 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_129323468_129324020 0.33 PLXND1
 plexin D1
 1917
 0.3
chr14_106375242_106375393 0.30 ENSG00000237197
 .
 465
 0.3
chr2_206546644_206547002 0.27 NRP2
 neuropilin 2
 401
 0.91
chr6_56707311_56707814 0.25 DST
 dystonin
 381
 0.81
chr6_27759279_27759446 0.24 HIST1H2BL
 histone cluster 1, H2bl
 16347
 0.08
chr2_110372829_110373268 0.24 SOWAHC
 sosondowah ankyrin repeat domain family member C
 1137
 0.38
chr19_49866237_49866676 0.24 DKKL1
 dickkopf-like 1
 125
 0.85
chr12_41086868_41087222 0.24 CNTN1
 contactin 1
 691
 0.81
chr10_112116910_112117211 0.24 SMNDC1
 survival motor neuron domain containing 1
 52351
 0.13
chr17_39940794_39940945 0.24 JUP
 junction plakoglobin
 538
 0.62
chr5_132166171_132166684 0.23 SHROOM1
 shroom family member 1
 76
 0.95
chr10_123873306_123873579 0.23 TACC2
 transforming, acidic coiled-coil containing protein 2
 888
 0.71
chr6_56707814_56708209 0.22 DST
 dystonin
 2
 0.95
chr20_30457693_30458808 0.22 DUSP15
 dual specificity phosphatase 15
 125
 0.67
chr21_32931442_32932281 0.21 AP000251.3
303
 0.71
chr13_103052448_103053000 0.21 FGF14
 fibroblast growth factor 14
 1400
 0.51
chr8_101522130_101522303 0.21 KB-1615E4.3
17460
 0.16
chr17_7119375_7119874 0.21 ACADVL
 acyl-CoA dehydrogenase, very long chain
 820
 0.27
chr11_75272983_75274329 0.21 SERPINH1
 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
 216
 0.91
chr8_103741653_103741928 0.20 ENSG00000266799
 .
 4157
 0.28
chr20_55204347_55205219 0.20 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 425
 0.81
chr7_2728372_2728661 0.20 AMZ1
 archaelysin family metallopeptidase 1
 680
 0.72
chr2_101435988_101436190 0.19 NPAS2
 neuronal PAS domain protein 2
 525
 0.8
chr13_113764635_113765129 0.19 F7
 coagulation factor VII (serum prothrombin conversion accelerator)
 4761
 0.13
chr8_37552103_37552726 0.19 ZNF703
 zinc finger protein 703
 855
 0.5
chr7_100464814_100466140 0.18 TRIP6
 thyroid hormone receptor interactor 6
 717
 0.47
chr21_46875019_46875466 0.18 COL18A1
 collagen, type XVIII, alpha 1
 161
 0.95
chr2_151342879_151343387 0.18 RND3
 Rho family GTPase 3
 1048
 0.71
chr6_88875424_88876640 0.18 CNR1
 cannabinoid receptor 1 (brain)
 46
 0.99
chr1_86043549_86043775 0.18 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 271
 0.9
chr2_238395971_238396408 0.18 MLPH
 melanophilin
 270
 0.92
chr4_86700818_86700973 0.18 ARHGAP24
 Rho GTPase activating protein 24
 1036
 0.65
chr4_169552961_169553147 0.18 PALLD
 palladin, cytoskeletal associated protein
 286
 0.92
chr9_136858110_136858615 0.17 VAV2
 vav 2 guanine nucleotide exchange factor
 636
 0.73
chr22_29702254_29703430 0.17 GAS2L1
 growth arrest-specific 2 like 1
 171
 0.91
chr4_3621829_3621980 0.17 LINC00955
 long intergenic non-protein coding RNA 955
 43308
 0.16
chr5_180631418_180632621 0.17 TRIM7
 tripartite motif containing 7
 153
 0.85
chr7_3082844_3083007 0.17 CARD11
 caspase recruitment domain family, member 11
 554
 0.82
chr4_77356334_77356485 0.17 SHROOM3
 shroom family member 3
 156
 0.95
chr1_109372974_109373275 0.17 AKNAD1
 AKNA domain containing 1
 22215
 0.15
chr11_62312562_62314176 0.17 RP11-864I4.4
102
 0.64
chr11_27722222_27723091 0.16 BDNF
 brain-derived neurotrophic factor
 56
 0.98
chr17_20491916_20492779 0.16 CDRT15L2
 CMT1A duplicated region transcript 15-like 2
 9310
 0.21
chr3_126702505_126703684 0.16 PLXNA1
 plexin A1
 4343
 0.34
chr15_74428208_74428697 0.16 ISLR2
 immunoglobulin superfamily containing leucine-rich repeat 2
 4209
 0.15
chr4_186065143_186065302 0.16 SLC25A4
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
 827
 0.63
chr3_118753063_118753796 0.16 IGSF11
 immunoglobulin superfamily, member 11
 146
 0.97
chr1_98510769_98511355 0.16 ENSG00000225206
 .
 155
 0.98
chr4_114900343_114900754 0.16 ARSJ
 arylsulfatase family, member J
 309
 0.93
chr11_8103103_8103531 0.16 TUB
 tubby bipartite transcription factor
 408
 0.82
chr9_131903246_131903428 0.16 PPP2R4
 protein phosphatase 2A activator, regulatory subunit 4
 588
 0.63
chr15_73345145_73345907 0.15 NEO1
 neogenin 1
 575
 0.85
chr12_113859774_113860410 0.15 SDSL
 serine dehydratase-like
 50
 0.97
chr5_1594076_1595069 0.15 SDHAP3
 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
 1168
 0.53
chr9_126807806_126807963 0.15 RP11-85O21.5
13081
 0.17
chr4_75858398_75858601 0.15 PARM1
 prostate androgen-regulated mucin-like protein 1
 173
 0.97
chr11_414426_414987 0.15 SIGIRR
 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
 242
 0.84
chr8_8749576_8750657 0.15 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 1039
 0.53
chr2_241458991_241459173 0.15 ANKMY1
 ankyrin repeat and MYND domain containing 1
 862
 0.54
chr6_105585236_105585620 0.15 BVES-AS1
 BVES antisense RNA 1
 134
 0.78
chrX_69674453_69675874 0.15 DLG3
 discs, large homolog 3 (Drosophila)
 217
 0.75
chr5_132112834_132113698 0.15 SEPT8
 septin 8
 153
 0.93
chr22_45898941_45899504 0.15 FBLN1
 fibulin 1
 296
 0.92
chr1_1283171_1284080 0.15 DVL1
 dishevelled segment polarity protein 1
 867
 0.32
chr1_16085392_16086186 0.15 FBLIM1
 filamin binding LIM protein 1
 497
 0.68
chr2_238322230_238322381 0.14 COL6A3
 collagen, type VI, alpha 3
 486
 0.82
chr15_66999211_66999494 0.14 SMAD6
 SMAD family member 6
 1578
 0.48
chr7_27223025_27223257 0.14 HOXA11-AS
 HOXA11 antisense RNA
 996
 0.23
chr8_22409217_22409843 0.14 SORBS3
 sorbin and SH3 domain containing 3
 322
 0.81
chr19_39522130_39522840 0.14 FBXO27
 F-box protein 27
 680
 0.5
chr2_69868222_69868500 0.14 AAK1
 AP2 associated kinase 1
 2425
 0.31
chr7_37960238_37961117 0.14 EPDR1
 ependymin related 1
 245
 0.94
chr12_54411200_54411679 0.14 HOXC4
 homeobox C4
 724
 0.35
chr5_141931000_141931262 0.14 ENSG00000252831
 .
 17221
 0.21
chr21_45663502_45663653 0.14 ICOSLG
 inducible T-cell co-stimulator ligand
 2728
 0.16
chr5_38445912_38446355 0.14 EGFLAM
 EGF-like, fibronectin type III and laminin G domains
 435
 0.81
chr1_234676868_234677019 0.14 ENSG00000212144
 .
 52078
 0.12
chr2_177502027_177502943 0.14 ENSG00000252027
 .
 26919
 0.25
chr9_109182958_109183109 0.14 ENSG00000200131
 .
 259225
 0.02
chr7_55154680_55154908 0.14 EGFR
 epidermal growth factor receptor
 22622
 0.26
chr18_11689181_11689508 0.14 GNAL
 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
 389
 0.89
chr8_8242103_8242254 0.13 SGK223
 Tyrosine-protein kinase SgK223
 1830
 0.46
chr20_57427465_57427903 0.13 GNAS
 GNAS complex locus
 85
 0.95
chr2_238117038_238117287 0.13 AC112715.2
 Uncharacterized protein
 48572
 0.16
chr9_98273641_98273827 0.13 RP11-435O5.4
2593
 0.22
chr4_157997002_157997188 0.13 GLRB
 glycine receptor, beta
 114
 0.97
chr5_176074525_176075535 0.13 TSPAN17
 tetraspanin 17
 409
 0.77
chr11_33398103_33398382 0.13 ENSG00000223134
 .
 22231
 0.24
chr9_90691300_90691935 0.13 ENSG00000271923
 .
 78367
 0.1
chr18_35146776_35147412 0.13 CELF4
 CUGBP, Elav-like family member 4
 1094
 0.67
chr10_102880623_102881444 0.13 HUG1
1503
 0.28
chrY_4868538_4868692 0.13 PCDH11Y
 protocadherin 11 Y-linked
 348
 0.92
chr17_76320779_76321257 0.13 SOCS3
 suppressor of cytokine signaling 3
 35137
 0.12
chr1_240774575_240775223 0.13 GREM2
 gremlin 2, DAN family BMP antagonist
 550
 0.78
chr8_98776052_98776203 0.13 ENSG00000202399
 .
 8414
 0.18
chr1_111148867_111149493 0.13 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
 205
 0.94
chr10_48438476_48439044 0.13 GDF10
 growth differentiation factor 10
 216
 0.93
chr8_41680511_41680662 0.13 ENSG00000241834
 .
 17271
 0.17
chr8_33329381_33329846 0.13 FUT10
 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
 1024
 0.5
chr10_73759326_73759477 0.13 CHST3
 carbohydrate (chondroitin 6) sulfotransferase 3
 35278
 0.18
chr2_9239323_9239474 0.13 MBOAT2
 membrane bound O-acyltransferase domain containing 2
 95456
 0.08
chr9_137417944_137418506 0.12 COL5A1
 collagen, type V, alpha 1
 115395
 0.05
chr11_103407723_103407973 0.12 DYNC2H1
 dynein, cytoplasmic 2, heavy chain 1
 178877
 0.03
chr8_67434316_67434584 0.12 ENSG00000206949
 .
 20904
 0.17
chr2_233388631_233389191 0.12 CHRND
 cholinergic receptor, nicotinic, delta (muscle)
 1959
 0.19
chr16_88520261_88521174 0.12 ZFPM1
 zinc finger protein, FOG family member 1
 992
 0.52
chr2_23608861_23609561 0.12 KLHL29
 kelch-like family member 29
 1123
 0.67
chr10_16562894_16563258 0.12 C1QL3
 complement component 1, q subcomponent-like 3
 928
 0.63
chr10_44879737_44880262 0.12 CXCL12
 chemokine (C-X-C motif) ligand 12
 492
 0.84
chr8_59904812_59904963 0.12 RP11-328K2.1
610
 0.83
chr6_166721057_166722024 0.12 PRR18
 proline rich 18
 331
 0.9
chr11_111411049_111411648 0.12 LAYN
 layilin
 36
 0.96
chr3_124930827_124931211 0.12 SLC12A8
 solute carrier family 12, member 8
 590
 0.8
chr2_227662938_227664059 0.12 IRS1
 insulin receptor substrate 1
 977
 0.58
chr5_141703297_141704624 0.12 SPRY4
 sprouty homolog 4 (Drosophila)
 213
 0.88
chr1_19973947_19974889 0.12 NBL1
 neuroblastoma 1, DAN family BMP antagonist
 314
 0.87
chr2_238537007_238537316 0.12 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 942
 0.55
chr21_27011149_27011750 0.12 JAM2
 junctional adhesion molecule 2
 135
 0.96
chr2_238321225_238321570 0.12 COL6A3
 collagen, type VI, alpha 3
 1394
 0.45
chr19_5293472_5293908 0.12 PTPRS
 protein tyrosine phosphatase, receptor type, S
 427
 0.88
chr12_66122461_66123138 0.12 HMGA2
 high mobility group AT-hook 2
 95112
 0.08
chr7_36343354_36343505 0.12 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 6676
 0.18
chr1_6452561_6453085 0.12 ACOT7
 acyl-CoA thioesterase 7
 598
 0.47
chr1_228566293_228567025 0.12 RP11-245P10.8
15332
 0.09
chr10_14215918_14216465 0.12 RP11-397C18.2
99908
 0.08
chr15_39873424_39874712 0.12 THBS1
 thrombospondin 1
 774
 0.66
chr19_47933466_47933908 0.12 MEIS3
 Meis homeobox 3
 10907
 0.15
chr6_27661627_27662566 0.12 ENSG00000238648
 .
 62908
 0.08
chr3_111395798_111395949 0.12 PLCXD2-AS1
 PLCXD2 antisense RNA 1
 407
 0.83
chr6_140303862_140304013 0.12 ENSG00000252107
 .
 175894
 0.03
chr21_39543980_39544194 0.12 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 14959
 0.18
chr20_24449651_24449802 0.12 SYNDIG1
 synapse differentiation inducing 1
 109
 0.98
chr9_35489468_35490886 0.12 RUSC2
 RUN and SH3 domain containing 2
 53
 0.97
chr18_21242120_21242413 0.12 ANKRD29
 ankyrin repeat domain 29
 470
 0.83
chr11_73028814_73028965 0.12 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
 6279
 0.14
chr6_148663623_148664008 0.12 SASH1
 SAM and SH3 domain containing 1
 86
 0.98
chr12_122461524_122461791 0.12 BCL7A
 B-cell CLL/lymphoma 7A
 1865
 0.38
chr15_29862574_29862799 0.11 FAM189A1
 family with sequence similarity 189, member A1
 241
 0.95
chr17_2118811_2119625 0.11 AC130689.5
91
 0.93
chr2_149634014_149634165 0.11 KIF5C
 kinesin family member 5C
 1270
 0.45
chr10_72237920_72238421 0.11 PALD1
 phosphatase domain containing, paladin 1
 407
 0.85
chr16_72884781_72884932 0.11 ENSG00000251868
 .
 28965
 0.16
chr16_2077067_2078193 0.11 SLC9A3R2
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
 701
 0.35
chr2_69240059_69240934 0.11 ANTXR1
 anthrax toxin receptor 1
 33
 0.98
chr11_118783344_118784212 0.11 BCL9L
 B-cell CLL/lymphoma 9-like
 2165
 0.14
chr10_128076891_128077106 0.11 ADAM12
 ADAM metallopeptidase domain 12
 26
 0.99
chr14_27067583_27067941 0.11 NOVA1-AS1
 NOVA1 antisense RNA 1 (head to head)
 144
 0.9
chr12_7036475_7036704 0.11 ATN1
 atrophin 1
 887
 0.28
chr15_65647670_65647821 0.11 IGDCC3
 immunoglobulin superfamily, DCC subclass, member 3
 504
 0.77
chr14_30397301_30397598 0.11 PRKD1
 protein kinase D1
 501
 0.84
chr14_67878511_67879217 0.11 PLEK2
 pleckstrin 2
 53
 0.97
chr15_30483917_30484165 0.11 ENSG00000221785
 .
 46961
 0.09
chr17_59539414_59539608 0.11 RP11-15K2.2
1234
 0.41
chr5_42424322_42424771 0.11 GHR
 growth hormone receptor
 520
 0.88
chr3_179754024_179754473 0.11 PEX5L
 peroxisomal biogenesis factor 5-like
 310
 0.94
chr16_85591757_85591908 0.11 GSE1
 Gse1 coiled-coil protein
 53183
 0.13
chr19_17727488_17727789 0.11 CTD-3149D2.3
3107
 0.2
chr19_10542995_10543337 0.11 PDE4A
 phosphodiesterase 4A, cAMP-specific
 55
 0.95
chr6_86159887_86160764 0.11 NT5E
 5'-nucleotidase, ecto (CD73)
 498
 0.87
chr8_145490080_145490245 0.11 SCXA
 scleraxis homolog A (mouse)
 387
 0.72
chr1_113392068_113392383 0.11 SLC16A1
 solute carrier family 16 (monocarboxylate transporter), member 1
 86385
 0.07
chr19_39466589_39467071 0.11 FBXO17
 F-box protein 17
 280
 0.84
chr15_61520624_61520983 0.11 RORA
 RAR-related orphan receptor A
 715
 0.73
chr18_55469401_55470160 0.10 ATP8B1
 ATPase, aminophospholipid transporter, class I, type 8B, member 1
 547
 0.82
chr12_56137339_56138382 0.10 GDF11
 growth differentiation factor 11
 677
 0.47
chr11_117185897_117186711 0.10 BACE1
 beta-site APP-cleaving enzyme 1
 210
 0.87
chr1_99469796_99470269 0.10 RP5-896L10.1
200
 0.74
chr2_66803645_66804000 0.10 MEIS1
 Meis homeobox 1
 67763
 0.13
chr5_14146856_14147086 0.10 TRIO
 trio Rho guanine nucleotide exchange factor
 3142
 0.4
chr13_103450865_103451730 0.10 KDELC1
 KDEL (Lys-Asp-Glu-Leu) containing 1
 60
 0.54
chr16_70749372_70749620 0.10 VAC14
 Vac14 homolog (S. cerevisiae)
 15348
 0.13
chr5_81685080_81685386 0.10 ATP6AP1L
 ATPase, H+ transporting, lysosomal accessory protein 1-like
 84067
 0.1
chr17_81067040_81067233 0.10 METRNL
 meteorin, glial cell differentiation regulator-like
 15142
 0.24
chr21_33784461_33785454 0.10 EVA1C
 eva-1 homolog C (C. elegans)
 36
 0.97
chr17_62754772_62754939 0.10 RP13-104F24.1
134
 0.96
chr9_137554285_137554504 0.10 COL5A1-AS1
 COL5A1 antisense RNA 1
 9705
 0.21
chr1_113243148_113243677 0.10 RHOC
 ras homolog family member C
 4131
 0.12
chr7_93931316_93931604 0.10 COL1A2
 collagen, type I, alpha 2
 92413
 0.09
chr17_71334494_71334713 0.10 CDC42EP4
 CDC42 effector protein (Rho GTPase binding) 4
 26289
 0.18
chr2_20795534_20795685 0.10 HS1BP3-IT1
 HS1BP3 intronic transcript 1 (non-protein coding)
 3301
 0.28
chr17_42072137_42072373 0.10 PYY
 peptide YY
 9582
 0.1
chr6_130690776_130691119 0.10 TMEM200A
 transmembrane protein 200A
 4068
 0.25
chr12_132088587_132088738 0.10 ENSG00000212154
 .
 56946
 0.14
chr12_52701821_52702383 0.10 RP11-845M18.6
53
 0.94
chrX_152764727_152764878 0.10 HAUS7
 HAUS augmin-like complex, subunit 7
 3824
 0.14
chr1_87669967_87670118 0.10 ENSG00000221222
 .
 53061
 0.16
chr7_138666479_138666949 0.10 KIAA1549
 KIAA1549
 650
 0.77
chr17_58104120_58104612 0.10 ENSG00000263422
 .
 15437
 0.11
chr19_18717102_18717255 0.10 CRLF1
 cytokine receptor-like factor 1
 482
 0.56
chr17_8230051_8230853 0.10 ENSG00000212206
 .
 2449
 0.13
chr19_7939410_7939591 0.10 CTD-3193O13.9
 Protein FLJ22184
 174
 0.87
chr7_6296015_6296815 0.10 CYTH3
 cytohesin 3
 15860
 0.17
chr10_3848106_3848440 0.10 KLF6
 Kruppel-like factor 6
 20800
 0.22
chr9_115774055_115774548 0.10 ZFP37
 ZFP37 zinc finger protein
 44667
 0.16
chr7_97839825_97840267 0.10 BHLHA15
 basic helix-loop-helix family, member a15
 693
 0.72
chr6_150921550_150922020 0.10 RP11-136K14.1
185
 0.87
chr6_100676507_100676883 0.10 RP1-121G13.2
198299
 0.03
chr14_106025749_106025900 0.10 ENSG00000263413
 .
 30526
 0.1
chr14_53418107_53419061 0.10 FERMT2
 fermitin family member 2
 569
 0.83
chr9_130330127_130331202 0.10 FAM129B
 family with sequence similarity 129, member B
 703
 0.67

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.3 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.2 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0072178 nephric duct morphogenesis(GO:0072178) mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0033083 regulation of immature T cell proliferation(GO:0033083)
0.0 0.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.0 GO:0001839 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0010829 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0032400 melanosome localization(GO:0032400)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0004954 prostanoid receptor activity(GO:0004954)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport