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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZNF410

Z-value: 0.53

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Transcription factors associated with ZNF410

Gene Symbol Gene ID Gene Info
ZNF410
ENSG00000119725.13 zinc finger protein 410

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_74352825_74353319ZNF4102480.860110-0.265.0e-01Click!
chr14_74354228_74354413ZNF4105590.618596-0.255.2e-01Click!
chr14_74353534_74354170ZNF410910.943032-0.157.0e-01Click!

Activity of the ZNF410 motif across conditions

Conditions sorted by the z-value of the ZNF410 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_21023989_21024197 0.34 PTPLAD2
 protein tyrosine phosphatase-like A domain containing 2
 7515
 0.22
chr12_6716856_6717254 0.31 CHD4
 chromodomain helicase DNA binding protein 4
 413
 0.67
chr8_108507547_108507698 0.31 ANGPT1
 angiopoietin 1
 399
 0.92
chr10_62331691_62331925 0.28 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 613
 0.85
chr16_50316518_50316669 0.24 ADCY7
 adenylate cyclase 7
 3155
 0.26
chr2_54825743_54825894 0.23 SPTBN1
 spectrin, beta, non-erythrocytic 1
 40287
 0.14
chr12_94599811_94599962 0.22 RP11-74K11.2
20066
 0.19
chr7_5682827_5682978 0.21 RNF216-IT1
 RNF216 intronic transcript 1 (non-protein coding)
 37190
 0.13
chr7_50256147_50256298 0.20 AC020743.2
73803
 0.1
chr12_6722182_6722818 0.20 CHD4
 chromodomain helicase DNA binding protein 4
 5858
 0.09
chr14_35605928_35606079 0.20 KIAA0391
 KIAA0391
 14038
 0.19
chr8_53372458_53372609 0.16 ST18
 suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
 50168
 0.17
chr12_66274639_66274849 0.15 RP11-366L20.2
 Uncharacterized protein
 614
 0.73
chr11_128586182_128586446 0.15 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 20396
 0.17
chr6_16695295_16695446 0.15 RP1-151F17.1
65999
 0.13
chr6_27104872_27105023 0.14 HIST1H4I
 histone cluster 1, H4i
 2129
 0.18
chr3_101555921_101556072 0.13 NFKBIZ
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
 9159
 0.19
chr2_218798521_218798672 0.12 TNS1
 tensin 1
 3289
 0.29
chr2_201612300_201612519 0.12 ENSG00000201737
 .
 27898
 0.13
chr17_79882093_79882377 0.12 MAFG
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
 827
 0.26
chr1_173175749_173175900 0.12 TNFSF4
 tumor necrosis factor (ligand) superfamily, member 4
 628
 0.81
chr12_69743882_69744071 0.12 LYZ
 lysozyme
 1810
 0.3
chr2_201924342_201924493 0.11 NDUFB3
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
 11739
 0.13
chr3_178866443_178867773 0.11 PIK3CA
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
 207
 0.94
chr3_101447790_101447941 0.11 CEP97
 centrosomal protein 97kDa
 4366
 0.17
chr19_48747671_48748205 0.10 CARD8
 caspase recruitment domain family, member 8
 3618
 0.15
chr17_35854577_35854849 0.10 DUSP14
 dual specificity phosphatase 14
 3143
 0.25
chr9_115981849_115982001 0.10 FKBP15
 FK506 binding protein 15, 133kDa
 1673
 0.28
chr10_114716477_114716628 0.10 RP11-57H14.2
4918
 0.24
chr3_128958405_128958556 0.09 COPG1
 coatomer protein complex, subunit gamma 1
 9969
 0.15
chr5_36725036_36725307 0.09 CTD-2353F22.1
104
 0.98
chr4_154178413_154178564 0.09 TRIM2
 tripartite motif containing 2
 74
 0.97
chr4_151509067_151509271 0.09 MAB21L2
 mab-21-like 2 (C. elegans)
 6092
 0.23
chr7_77200176_77200327 0.09 PTPN12
 protein tyrosine phosphatase, non-receptor type 12
 157
 0.97
chr2_161243980_161244427 0.09 ENSG00000252465
 .
 9276
 0.21
chr5_111110911_111111062 0.08 NREP
 neuronal regeneration related protein
 17071
 0.21
chr6_15421648_15421799 0.08 JARID2
 jumonji, AT rich interactive domain 2
 20634
 0.24
chr6_170921254_170921775 0.08 PDCD2
 programmed cell death 2
 27766
 0.19
chr2_236467191_236467342 0.07 ENSG00000221704
 .
 13309
 0.22
chr11_74561071_74561376 0.07 ENSG00000242999
 .
 4268
 0.2
chr10_97501781_97501932 0.07 ENTPD1
 ectonucleoside triphosphate diphosphohydrolase 1
 13553
 0.21
chr3_156266030_156266252 0.07 SSR3
 signal sequence receptor, gamma (translocon-associated protein gamma)
 5773
 0.24
chr12_46776420_46777113 0.07 SLC38A2
 solute carrier family 38, member 2
 10116
 0.24
chr5_176901024_176901292 0.07 DBN1
 drebrin 1
 244
 0.85
chr5_124090344_124090580 0.07 ZNF608
 zinc finger protein 608
 5962
 0.15
chr14_73927569_73927740 0.07 ENSG00000251393
 .
 1475
 0.32
chr2_48599257_48599408 0.07 ENSG00000251889
 .
 31367
 0.18
chr1_39624513_39624771 0.07 ENSG00000222378
 .
 4674
 0.21
chr4_40561734_40561885 0.06 RBM47
 RNA binding motif protein 47
 43819
 0.15
chr9_83413109_83413260 0.06 ENSG00000221581
 .
 63940
 0.16
chr13_21654404_21654812 0.06 LATS2
 large tumor suppressor kinase 2
 18922
 0.14
chr11_57334584_57335055 0.06 UBE2L6
 ubiquitin-conjugating enzyme E2L 6
 20
 0.96
chr16_17087479_17087630 0.06 CTD-2576D5.4
140807
 0.05
chr10_111659026_111659177 0.06 XPNPEP1
 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
 8476
 0.22
chr6_1841402_1841553 0.06 FOXC1
 forkhead box C1
 230796
 0.02
chr5_14154391_14154790 0.06 TRIO
 trio Rho guanine nucleotide exchange factor
 10761
 0.32
chr14_56584316_56584807 0.06 PELI2
 pellino E3 ubiquitin protein ligase family member 2
 29
 0.98
chr13_78410734_78410885 0.05 EDNRB
 endothelin receptor type B
 82136
 0.08
chr11_10064267_10064418 0.05 SBF2
 SET binding factor 2
 49691
 0.16
chr3_119922105_119922256 0.05 ENSG00000206721
 .
 6987
 0.22
chr10_116582241_116583014 0.05 FAM160B1
 family with sequence similarity 160, member B1
 1098
 0.64
chr2_45794929_45795131 0.05 SRBD1
 S1 RNA binding domain 1
 124
 0.96
chr6_163826222_163826373 0.05 QKI
 QKI, KH domain containing, RNA binding
 9378
 0.32
chr19_1064805_1065015 0.05 HMHA1
 histocompatibility (minor) HA-1
 1012
 0.32
chr8_127989397_127989548 0.05 ENSG00000212451
 .
 305705
 0.01
chr8_86371428_86371579 0.05 RP11-317J10.2
3780
 0.21
chr3_63957905_63958056 0.05 ATXN7
 ataxin 7
 4560
 0.17
chr6_85134970_85135121 0.05 KIAA1009
 KIAA1009
 197692
 0.03
chr14_67828227_67828378 0.04 EIF2S1
 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
 1029
 0.38
chr6_41666551_41666729 0.04 TFEB
 transcription factor EB
 7038
 0.13
chr10_7670560_7670711 0.04 ITIH5
 inter-alpha-trypsin inhibitor heavy chain family, member 5
 9012
 0.26
chr12_84274084_84274235 0.04 ENSG00000221148
 .
 303068
 0.01
chr5_40615963_40616141 0.04 ENSG00000199552
 .
 39013
 0.18
chrX_143576959_143577110 0.04 ENSG00000201912
 .
 561594
 0.0
chr11_15179065_15179216 0.04 INSC
 inscuteable homolog (Drosophila)
 8486
 0.3
chr2_65291860_65292299 0.04 CEP68
 centrosomal protein 68kDa
 8480
 0.18
chr20_36629792_36630028 0.04 TTI1
 TELO2 interacting protein 1
 12395
 0.17
chrX_153637082_153637306 0.04 DNASE1L1
 deoxyribonuclease I-like 1
 418
 0.63
chr5_172261659_172261898 0.04 ERGIC1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 364
 0.87
chr8_123440615_123440780 0.04 ENSG00000238901
 .
 242833
 0.02
chr12_123199549_123199700 0.04 HCAR3
 hydroxycarboxylic acid receptor 3
 1815
 0.27
chr12_109118598_109118801 0.04 CORO1C
 coronin, actin binding protein, 1C
 5628
 0.17
chr2_202519598_202519749 0.04 ENSG00000222972
 .
 8234
 0.16
chr5_132385127_132385278 0.04 HSPA4
 heat shock 70kDa protein 4
 2452
 0.27
chr1_206137311_206137809 0.04 RP11-312O7.2
268
 0.52
chrX_24073135_24073641 0.04 EIF2S3
 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
 300
 0.91
chr4_22516047_22517223 0.04 GPR125
 G protein-coupled receptor 125
 985
 0.72
chr7_17018287_17018438 0.03 AGR3
 anterior gradient 3
 96751
 0.08
chr9_116384320_116384471 0.03 RGS3
 regulator of G-protein signaling 3
 28629
 0.19
chr9_41563760_41563911 0.03 SPATA31A5
 SPATA31 subfamily A, member 5
 63156
 0.15
chr19_36618863_36619073 0.03 CAPNS1
 calpain, small subunit 1
 11509
 0.09
chr20_23067023_23067351 0.03 CD93
 CD93 molecule
 210
 0.93
chr1_98496294_98496445 0.03 ENSG00000225206
 .
 14538
 0.29
chr22_37679105_37679462 0.03 CYTH4
 cytohesin 4
 755
 0.62
chr12_13499997_13500148 0.03 C12orf36
 chromosome 12 open reading frame 36
 29292
 0.21
chr12_65071079_65071230 0.03 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 19175
 0.13
chr13_28997424_28997626 0.03 FLT1
 fms-related tyrosine kinase 1
 71707
 0.12
chr15_85295872_85296023 0.03 RP11-7M10.2
406
 0.79
chr1_225942852_225943140 0.03 ENSG00000223306
 .
 14019
 0.14
chr1_175323766_175323917 0.03 RP3-518E13.2
47487
 0.16
chr1_43416112_43416263 0.03 SLC2A1
 solute carrier family 2 (facilitated glucose transporter), member 1
 8313
 0.19
chr7_87504669_87504826 0.02 DBF4
 DBF4 homolog (S. cerevisiae)
 797
 0.47
chr5_178956987_178957198 0.02 RUFY1
 RUN and FYVE domain containing 1
 20467
 0.17
chr13_42151532_42151903 0.02 ENSG00000264190
 .
 9186
 0.26
chr9_39418756_39418907 0.02 CTD-2173L22.4
42860
 0.18
chr10_61661518_61661669 0.02 CCDC6
 coiled-coil domain containing 6
 4821
 0.3
chrX_69512839_69512990 0.02 KIF4A
 kinesin family member 4A
 2974
 0.15
chr5_119488092_119488243 0.02 ENSG00000251975
 .
 185181
 0.03
chr10_127511437_127512239 0.02 UROS
 uroporphyrinogen III synthase
 21
 0.79
chr8_74904321_74904899 0.02 LY96
 lymphocyte antigen 96
 949
 0.5
chr8_94752281_94753315 0.02 RBM12B
 RNA binding motif protein 12B
 148
 0.72
chr7_13920022_13920238 0.02 ETV1
 ets variant 1
 105936
 0.08
chr17_57701437_57701588 0.02 CLTC
 clathrin, heavy chain (Hc)
 4219
 0.23
chrX_64925761_64925912 0.02 MSN
 moesin
 38299
 0.22
chr10_134363355_134363506 0.02 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 11787
 0.21
chr9_39948000_39948151 0.02 SPATA31A2
 SPATA31 subfamily A, member 2
 63100
 0.14
chr2_62638898_62639095 0.02 ENSG00000241625
 .
 79317
 0.09
chr14_92571968_92572886 0.02 ATXN3
 ataxin 3
 479
 0.77
chr17_66437196_66437347 0.02 WIPI1
 WD repeat domain, phosphoinositide interacting 1
 7559
 0.21
chr11_8008996_8010000 0.02 EIF3F
 eukaryotic translation initiation factor 3, subunit F
 610
 0.64
chr2_210868078_210868268 0.02 RPE
 ribulose-5-phosphate-3-epimerase
 787
 0.63
chr1_16177042_16177194 0.02 RP11-169K16.9
2476
 0.21
chr13_46741782_46741933 0.02 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 797
 0.56
chr15_40226407_40226907 0.02 EIF2AK4
 eukaryotic translation initiation factor 2 alpha kinase 4
 280
 0.88
chr11_85778298_85779603 0.02 PICALM
 phosphatidylinositol binding clathrin assembly protein
 872
 0.65
chr9_113598301_113598563 0.02 MUSK
 muscle, skeletal, receptor tyrosine kinase
 60805
 0.12
chr19_13023816_13024331 0.02 SYCE2
 synaptonemal complex central element protein 2
 6017
 0.06
chr12_114284871_114285022 0.02 RP11-780K2.1
85428
 0.1
chr5_72111935_72112277 0.02 TNPO1
 transportin 1
 33
 0.8
chr1_40847512_40847991 0.02 SMAP2
 small ArfGAP2
 7431
 0.18
chr8_134090212_134090363 0.01 SLA
 Src-like-adaptor
 17684
 0.22
chr3_125635457_125636442 0.01 FAM86JP
 family with sequence similarity 86, member J, pseudogene
 482
 0.8
chr15_102061524_102061675 0.01 PCSK6
 proprotein convertase subtilisin/kexin type 6
 31412
 0.2
chr9_129252632_129253068 0.01 ENSG00000221768
 .
 40420
 0.14
chr3_168825087_168825238 0.01 MECOM
 MDS1 and EVI1 complex locus
 20660
 0.29
chr1_221209086_221209419 0.01 HLX
 H2.0-like homeobox
 154668
 0.04
chr1_143913778_143914315 0.01 FAM72D
 family with sequence similarity 72, member D
 903
 0.56
chr18_32663220_32663371 0.01 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 41681
 0.2
chr19_9524867_9525018 0.01 ZNF266
 zinc finger protein 266
 4815
 0.19
chr7_37759942_37760093 0.01 GPR141
 G protein-coupled receptor 141
 19979
 0.23
chr14_21851512_21852227 0.01 SUPT16H
 suppressor of Ty 16 homolog (S. cerevisiae)
 271
 0.69
chr5_95144892_95145187 0.01 GLRX
 glutaredoxin (thioltransferase)
 13376
 0.15
chr6_160450858_160451009 0.01 AIRN
 antisense of IGF2R non-protein coding RNA
 22237
 0.21
chr8_37888134_37889006 0.01 EIF4EBP1
 eukaryotic translation initiation factor 4E binding protein 1
 711
 0.62
chr15_52788839_52789035 0.01 MYO5A
 myosin VA (heavy chain 12, myoxin)
 32101
 0.18
chr22_46134071_46134222 0.01 ATXN10
 ataxin 10
 473
 0.84
chr6_71544283_71544434 0.01 SMAP1
 small ArfGAP 1
 61266
 0.15
chr10_70165992_70166978 0.01 RUFY2
 RUN and FYVE domain containing 2
 461
 0.8
chr9_14309575_14309740 0.01 NFIB
 nuclear factor I/B
 1645
 0.46
chr14_71066645_71067347 0.01 MED6
 mediator complex subunit 6
 364
 0.87
chr13_46742646_46742820 0.01 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 79
 0.95
chr6_121760674_121760877 0.01 GJA1
 gap junction protein, alpha 1, 43kDa
 3937
 0.22
chr14_92874571_92874722 0.01 SLC24A4
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
 77
 0.98
chr1_231671479_231671630 0.01 TSNAX
 translin-associated factor X
 7153
 0.2
chr17_13689312_13689463 0.01 ENSG00000236088
 .
 6480
 0.33
chr14_32842058_32842209 0.01 AKAP6
 A kinase (PRKA) anchor protein 6
 43527
 0.15
chr13_86099472_86099623 0.01 ENSG00000207012
 .
 59441
 0.17
chr19_58521386_58521539 0.01 ZNF606
 zinc finger protein 606
 6745
 0.11
chr2_60755895_60756046 0.01 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 24570
 0.2
chr4_37978441_37978791 0.01 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 315
 0.92
chr3_88483370_88483521 0.01 ENSG00000207316
 .
 3104
 0.41
chr9_80408593_80408744 0.01 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 29247
 0.25
chr1_27079827_27079978 0.00 ENSG00000266138
 .
 10213
 0.13
chr13_103353320_103353471 0.00 METTL21C
 methyltransferase like 21C
 6541
 0.16
chr1_87803835_87803986 0.00 LMO4
 LIM domain only 4
 6559
 0.32
chr8_93547538_93547689 0.00 ENSG00000221172
 .
 99950
 0.09
chr18_55469401_55470160 0.00 ATP8B1
 ATPase, aminophospholipid transporter, class I, type 8B, member 1
 547
 0.82
chr16_14800704_14800855 0.00 RP11-82O18.2
133
 0.93
chr12_95596867_95597053 0.00 FGD6
 FYVE, RhoGEF and PH domain containing 6
 14195
 0.18
chr12_57940971_57941264 0.00 DCTN2
 dynactin 2 (p50)
 3
 0.94
chr3_102392529_102392885 0.00 ENSG00000201065
 .
 81307
 0.12
chr8_42409378_42409529 0.00 SMIM19
 small integral membrane protein 19
 7882
 0.18
chr14_24611030_24611338 0.00 EMC9
 ER membrane protein complex subunit 9
 387
 0.61
chrX_78412852_78413003 0.00 GPR174
 G protein-coupled receptor 174
 13542
 0.31
chr18_43554027_43554236 0.00 EPG5
 ectopic P-granules autophagy protein 5 homolog (C. elegans)
 6891
 0.21
chr16_53751617_53751768 0.00 FTO
 fat mass and obesity associated
 13598
 0.22
chr2_71763544_71763695 0.00 DYSF
 dysferlin
 69787
 0.12
chr12_121726859_121727365 0.00 CAMKK2
 calcium/calmodulin-dependent protein kinase kinase 2, beta
 7377
 0.21
chr12_100988036_100988187 0.00 GAS2L3
 growth arrest-specific 2 like 3
 715
 0.75
chr12_62657622_62657800 0.00 USP15
 ubiquitin specific peptidase 15
 3502
 0.25
chr6_107816329_107816751 0.00 SOBP
 sine oculis binding protein homolog (Drosophila)
 5378
 0.23
chr10_5509058_5509209 0.00 NET1
 neuroepithelial cell transforming 1
 20559
 0.14
chr11_114034692_114034843 0.00 ENSG00000221112
 .
 77116
 0.09
chr10_126368779_126368930 0.00 FAM53B-AS1
 FAM53B antisense RNA 1
 23340
 0.19
chr17_37557069_37557922 0.00 FBXL20
 F-box and leucine-rich repeat protein 20
 381
 0.59
chr2_179279129_179279546 0.00 AC009948.5
587
 0.72
chr15_48469342_48470564 0.00 MYEF2
 myelin expression factor 2
 597
 0.66

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF410

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins