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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZNF423

Z-value: 0.63

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Transcription factors associated with ZNF423

Gene Symbol Gene ID Gene Info
ZNF423
ENSG00000102935.7 zinc finger protein 423

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr16_49629926_49630278ZNF423446610.1811520.854.0e-03Click!
chr16_49654580_49654731ZNF423201080.2449980.751.9e-02Click!
chr16_49697543_49697694ZNF4235180.8356480.722.8e-02Click!
chr16_49862024_49862175ZNF42311780.5470250.713.0e-02Click!
chr16_49698067_49698218ZNF42360.9840720.694.1e-02Click!

Activity of the ZNF423 motif across conditions

Conditions sorted by the z-value of the ZNF423 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_150464397_150464642 0.30 PPP1R14C
 protein phosphatase 1, regulatory (inhibitor) subunit 14C
 307
 0.91
chr3_114173030_114173441 0.29 ZBTB20
 zinc finger and BTB domain containing 20
 295
 0.94
chr13_95619763_95620412 0.28 ENSG00000252335
 .
 51402
 0.18
chr22_30641304_30641455 0.28 RP1-102K2.8
605
 0.52
chr1_14924992_14926197 0.28 KAZN
 kazrin, periplakin interacting protein
 381
 0.93
chr17_17725795_17725961 0.28 SREBF1
 sterol regulatory element binding transcription factor 1
 1054
 0.42
chr12_66216582_66216994 0.27 HMGA2
 high mobility group AT-hook 2
 1123
 0.55
chr1_20915430_20915891 0.27 CDA
 cytidine deaminase
 219
 0.93
chr10_63212172_63213035 0.27 RP11-809M12.1
206
 0.83
chr19_41725215_41725482 0.26 AXL
 AXL receptor tyrosine kinase
 208
 0.89
chr6_150464730_150464955 0.25 PPP1R14C
 protein phosphatase 1, regulatory (inhibitor) subunit 14C
 630
 0.74
chrX_39548256_39548819 0.25 ENSG00000263730
 .
 28067
 0.24
chr3_133614813_133615159 0.24 RAB6B
 RAB6B, member RAS oncogene family
 306
 0.92
chr13_114541163_114541465 0.24 GAS6
 growth arrest-specific 6
 2297
 0.34
chr1_27928484_27928752 0.24 AHDC1
 AT hook, DNA binding motif, containing 1
 1484
 0.34
chr8_89340038_89340774 0.24 MMP16
 matrix metallopeptidase 16 (membrane-inserted)
 152
 0.73
chr20_6032553_6033205 0.23 LRRN4
 leucine rich repeat neuronal 4
 1816
 0.35
chr2_241860515_241860848 0.22 AC104809.3
 Protein LOC728763
 1305
 0.38
chr19_45147190_45148055 0.22 PVR
 poliovirus receptor
 225
 0.9
chr2_127976513_127977351 0.21 CYP27C1
 cytochrome P450, family 27, subfamily C, polypeptide 1
 722
 0.74
chr2_113593127_113593420 0.21 IL1B
 interleukin 1, beta
 738
 0.63
chr19_1240029_1240222 0.21 ATP5D
 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
 1624
 0.18
chr19_36024645_36024970 0.20 GAPDHS
 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
 493
 0.62
chr1_208132304_208132634 0.20 CD34
 CD34 molecule
 47722
 0.19
chr11_64122826_64123177 0.20 RPS6KA4
 ribosomal protein S6 kinase, 90kDa, polypeptide 4
 3619
 0.11
chr20_57090585_57090835 0.20 APCDD1L
 adenomatosis polyposis coli down-regulated 1-like
 523
 0.83
chr19_54483356_54483962 0.20 ENSG00000215998
 .
 1902
 0.19
chr7_20370368_20370519 0.19 ITGB8
 integrin, beta 8
 118
 0.93
chr4_74735225_74735723 0.19 CXCL1
 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
 353
 0.85
chr1_65991788_65991976 0.19 LEPR
 leptin receptor
 39347
 0.14
chr10_72976782_72977411 0.19 UNC5B-AS1
 UNC5B antisense RNA 1
 486
 0.73
chr22_29598883_29599280 0.19 EMID1
 EMI domain containing 1
 2759
 0.2
chr4_156681206_156681472 0.19 GUCY1B3
 guanylate cyclase 1, soluble, beta 3
 728
 0.72
chr7_23508285_23508467 0.19 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 1710
 0.33
chr2_218874347_218874698 0.19 TNS1
 tensin 1
 6804
 0.19
chr22_46482353_46482522 0.19 FLJ27365
 hsa-mir-4763
 554
 0.6
chr13_96296247_96296898 0.18 DZIP1
 DAZ interacting zinc finger protein 1
 372
 0.89
chr16_88870757_88870966 0.18 CDT1
 chromatin licensing and DNA replication factor 1
 1240
 0.28
chr12_81330378_81331020 0.17 LIN7A
 lin-7 homolog A (C. elegans)
 784
 0.37
chr17_8295251_8295402 0.17 RNF222
 ring finger protein 222
 1481
 0.24
chr21_35831656_35831815 0.17 KCNE1
 potassium voltage-gated channel, Isk-related family, member 1
 167
 0.94
chr7_43288672_43288925 0.17 AC004692.4
43
 0.98
chr7_73704780_73705014 0.17 CLIP2
 CAP-GLY domain containing linker protein 2
 1092
 0.51
chr2_97136526_97136687 0.17 NEURL3
 neuralized E3 ubiquitin protein ligase 3
 30055
 0.16
chr19_44905150_44906080 0.17 ZNF285
 zinc finger protein 285
 126
 0.54
chr8_55065813_55066181 0.17 ENSG00000251835
 .
 555
 0.79
chr4_74809740_74810515 0.17 PF4
 platelet factor 4
 37714
 0.11
chr17_71301523_71301822 0.17 CDC42EP4
 CDC42 effector protein (Rho GTPase binding) 4
 5875
 0.2
chr16_4424352_4424847 0.16 VASN
 vasorin
 2750
 0.17
chr19_10947512_10947663 0.16 C19orf38
 chromosome 19 open reading frame 38
 336
 0.63
chr4_62067084_62067588 0.16 LPHN3
 latrophilin 3
 360
 0.94
chr4_74903896_74904220 0.16 CXCL3
 chemokine (C-X-C motif) ligand 3
 348
 0.83
chr7_47620495_47620884 0.16 TNS3
 tensin 3
 540
 0.86
chr15_101629242_101629566 0.16 RP11-505E24.2
3133
 0.3
chr7_37960238_37961117 0.15 EPDR1
 ependymin related 1
 245
 0.94
chr10_106079408_106079559 0.15 RP11-127L20.5
7584
 0.13
chr10_114712061_114712425 0.15 RP11-57H14.2
609
 0.69
chr17_37729930_37730438 0.15 ENSG00000222777
 .
 27687
 0.12
chr4_74734701_74735215 0.15 CXCL1
 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
 163
 0.94
chr13_33804184_33804599 0.15 STARD13
 StAR-related lipid transfer (START) domain containing 13
 24248
 0.2
chr5_9544908_9545592 0.15 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 937
 0.56
chr19_17579873_17580031 0.15 SLC27A1
 solute carrier family 27 (fatty acid transporter), member 1
 374
 0.71
chr5_167792475_167792729 0.15 WWC1
 WW and C2 domain containing 1
 5824
 0.29
chrX_19140154_19140583 0.15 GPR64
 G protein-coupled receptor 64
 211
 0.97
chr18_500844_501279 0.15 COLEC12
 collectin sub-family member 12
 339
 0.89
chr16_70719186_70719575 0.15 MTSS1L
 metastasis suppressor 1-like
 589
 0.67
chr20_1298176_1298327 0.15 SDCBP2
 syndecan binding protein (syntenin) 2
 3934
 0.16
chr1_78354680_78354975 0.14 NEXN-AS1
 NEXN antisense RNA 1
 397
 0.54
chr11_66082073_66082224 0.14 RP11-867G23.13
1824
 0.12
chr18_11149170_11149978 0.14 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 987
 0.72
chr9_140301738_140301959 0.14 ENSG00000272272
 .
 13748
 0.11
chr17_7483283_7483711 0.14 CD68
 CD68 molecule
 316
 0.62
chr13_114541513_114541687 0.14 GAS6
 growth arrest-specific 6
 2583
 0.32
chr1_54844833_54844984 0.14 SSBP3
 single stranded DNA binding protein 3
 26269
 0.19
chr9_18438384_18438699 0.14 ADAMTSL1
 ADAMTS-like 1
 35351
 0.23
chr9_112542645_112542955 0.13 AKAP2
 A kinase (PRKA) anchor protein 2
 31
 0.37
chr7_100880679_100880896 0.13 CLDN15
 claudin 15
 254
 0.85
chr17_58164259_58164533 0.13 HEATR6
 HEAT repeat containing 6
 8104
 0.14
chr22_50698815_50699396 0.13 MAPK12
 mitogen-activated protein kinase 12
 632
 0.49
chr13_27757022_27757206 0.13 USP12-AS2
 USP12 antisense RNA 2 (head to head)
 10718
 0.14
chr5_115911326_115911646 0.13 SEMA6A
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
 856
 0.75
chr12_43945597_43946279 0.13 ADAMTS20
 ADAM metallopeptidase with thrombospondin type 1 motif, 20
 214
 0.97
chr1_156072742_156072967 0.13 LMNA
 lamin A/C
 11607
 0.1
chr11_69460044_69460271 0.13 CCND1
 cyclin D1
 4183
 0.25
chr5_176935395_176936034 0.13 DOK3
 docking protein 3
 1113
 0.32
chr2_14772882_14773213 0.13 FAM84A
 family with sequence similarity 84, member A
 223
 0.94
chr7_101268427_101268664 0.13 MYL10
 myosin, light chain 10, regulatory
 4031
 0.33
chr12_32551927_32552214 0.13 FGD4
 FYVE, RhoGEF and PH domain containing 4
 393
 0.86
chr7_136555280_136555665 0.13 CHRM2
 cholinergic receptor, muscarinic 2
 1603
 0.4
chr5_82768204_82768925 0.13 VCAN
 versican
 820
 0.75
chr6_139014672_139015008 0.13 RP11-390P2.4
616
 0.63
chr7_101460813_101461304 0.13 CUX1
 cut-like homeobox 1
 138
 0.97
chr2_26785075_26785548 0.12 C2orf70
 chromosome 2 open reading frame 70
 139
 0.96
chr2_28601499_28601815 0.12 FOSL2
 FOS-like antigen 2
 14012
 0.17
chr15_31631055_31631206 0.12 KLF13
 Kruppel-like factor 13
 1006
 0.69
chr1_12656148_12656570 0.12 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 38
 0.98
chr1_240161229_240161618 0.12 FMN2
 formin 2
 16225
 0.27
chr6_10418997_10419238 0.12 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
 754
 0.63
chr15_25199832_25199983 0.12 SNRPN
 small nuclear ribonucleoprotein polypeptide N
 167
 0.55
chr5_139050794_139051015 0.12 CXXC5
 CXXC finger protein 5
 4117
 0.25
chr16_1458660_1458855 0.12 LA16c-312E8.2
78
 0.93
chr11_111794191_111794413 0.12 CRYAB
 crystallin, alpha B
 144
 0.91
chr17_76879212_76879961 0.12 TIMP2
 TIMP metallopeptidase inhibitor 2
 9354
 0.14
chr9_139429643_139429794 0.12 RP11-413M3.4
7615
 0.1
chr19_10399295_10399446 0.12 CTD-2369P2.8
325
 0.66
chr1_1292304_1292633 0.12 MXRA8
 matrix-remodelling associated 8
 1447
 0.18
chr11_1329925_1330473 0.12 TOLLIP
 toll interacting protein
 650
 0.47
chr1_208137449_208137600 0.12 CD34
 CD34 molecule
 52777
 0.17
chr19_1154555_1155129 0.12 SBNO2
 strawberry notch homolog 2 (Drosophila)
 293
 0.85
chr6_85472288_85472456 0.12 TBX18
 T-box 18
 701
 0.8
chr5_14204410_14204680 0.12 TRIO
 trio Rho guanine nucleotide exchange factor
 20638
 0.29
chr7_30028817_30029270 0.12 SCRN1
 secernin 1
 285
 0.79
chr11_75210907_75211158 0.11 RP11-939C17.4
8404
 0.15
chr9_72658914_72659269 0.11 MAMDC2
 MAM domain containing 2
 594
 0.81
chr10_29922441_29923089 0.11 SVIL
 supervillin
 1136
 0.54
chr11_503866_504897 0.11 RNH1
 ribonuclease/angiogenin inhibitor 1
 171
 0.89
chrX_51239510_51239840 0.11 NUDT11
 nudix (nucleoside diphosphate linked moiety X)-type motif 11
 227
 0.96
chr7_64700247_64700513 0.11 ENSG00000265175
 .
 27929
 0.19
chr12_112560647_112560960 0.11 TRAFD1
 TRAF-type zinc finger domain containing 1
 2502
 0.22
chr10_104359700_104359851 0.11 ENSG00000207029
 .
 8494
 0.17
chr1_227506323_227506932 0.11 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
 452
 0.9
chr17_77756152_77756303 0.11 CBX2
 chromobox homolog 2
 4234
 0.16
chr12_105477204_105477480 0.11 ALDH1L2
 aldehyde dehydrogenase 1 family, member L2
 999
 0.49
chr4_177712658_177713139 0.11 VEGFC
 vascular endothelial growth factor C
 983
 0.71
chr21_45553858_45554178 0.11 C21orf33
 chromosome 21 open reading frame 33
 322
 0.87
chr17_39970124_39970275 0.11 FKBP10
 FK506 binding protein 10, 65 kDa
 1016
 0.29
chr7_5467738_5468320 0.11 TNRC18
 trinucleotide repeat containing 18
 2984
 0.19
chr4_8272289_8272466 0.11 HTRA3
 HtrA serine peptidase 3
 873
 0.65
chr11_14403032_14403213 0.11 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 17070
 0.25
chr6_21665058_21665374 0.11 SOX4
 SRY (sex determining region Y)-box 4
 71145
 0.14
chr14_103058041_103058305 0.11 RCOR1
 REST corepressor 1
 825
 0.6
chr3_46972745_46972896 0.11 PTH1R
 parathyroid hormone 1 receptor
 28731
 0.12
chr7_27191813_27192140 0.11 HOXA-AS3
 HOXA cluster antisense RNA 3
 2305
 0.1
chr20_4878730_4878881 0.11 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 1488
 0.39
chr17_15850937_15851088 0.11 ADORA2B
 adenosine A2b receptor
 2781
 0.26
chr3_32001454_32001950 0.11 OSBPL10
 oxysterol binding protein-like 10
 21090
 0.19
chr17_15870184_15870534 0.11 ADORA2B
 adenosine A2b receptor
 22128
 0.14
chr6_143014333_143014633 0.11 RP1-67K17.3
55097
 0.17
chr8_18942225_18942376 0.11 PSD3
 pleckstrin and Sec7 domain containing 3
 60
 0.99
chr7_28724839_28725039 0.11 CREB5
 cAMP responsive element binding protein 5
 659
 0.83
chr1_206255126_206255277 0.11 ENSG00000252692
 .
 5892
 0.18
chr18_67069113_67069341 0.11 DOK6
 docking protein 6
 936
 0.74
chr9_38067740_38068285 0.11 SHB
 Src homology 2 domain containing adaptor protein B
 1196
 0.58
chr2_238813531_238813682 0.11 ENSG00000263723
 .
 35059
 0.15
chr17_12877207_12877393 0.11 ENSG00000266152
 .
 1158
 0.45
chrX_129657730_129658601 0.11 RBMX2
 RNA binding motif protein, X-linked 2
 122186
 0.05
chr2_120189452_120190154 0.11 TMEM37
 transmembrane protein 37
 358
 0.88
chr10_49678072_49678223 0.11 ARHGAP22
 Rho GTPase activating protein 22
 18477
 0.21
chr5_129240122_129240866 0.10 CHSY3
 chondroitin sulfate synthase 3
 329
 0.79
chr9_130659943_130660240 0.10 ST6GALNAC6
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
 200
 0.87
chr19_13392901_13393052 0.10 CACNA1A
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 6266
 0.22
chr5_150863261_150863412 0.10 ENSG00000200227
 .
 6198
 0.17
chr11_17096518_17096669 0.10 ENSG00000272034
 .
 302
 0.67
chr1_208133085_208133236 0.10 CD34
 CD34 molecule
 48413
 0.18
chr17_45277656_45277848 0.10 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
 8649
 0.12
chr8_104152453_104152604 0.10 BAALC
 brain and acute leukemia, cytoplasmic
 410
 0.69
chr17_79859390_79859541 0.10 NPB
 neuropeptide B
 520
 0.48
chr4_75480156_75480665 0.10 AREGB
 amphiregulin B
 219
 0.94
chr6_166074004_166074283 0.10 PDE10A
 phosphodiesterase 10A
 1414
 0.55
chr15_81072509_81072719 0.10 KIAA1199
 KIAA1199
 902
 0.65
chr11_61595808_61596402 0.10 FADS2
 fatty acid desaturase 2
 353
 0.64
chr1_119521934_119522435 0.10 TBX15
 T-box 15
 8244
 0.28
chr17_2613659_2614081 0.10 CLUH
 clustered mitochondria (cluA/CLU1) homolog
 622
 0.56
chr9_90131995_90132200 0.10 DAPK1
 death-associated protein kinase 1
 18177
 0.23
chr9_130308551_130308785 0.10 FAM129B
 family with sequence similarity 129, member B
 22699
 0.15
chr10_95225832_95226004 0.10 MYOF
 myoferlin
 16033
 0.19
chr1_16087111_16087637 0.10 FBLIM1
 filamin binding LIM protein 1
 2082
 0.2
chr4_75310406_75310883 0.10 AREG
 amphiregulin
 207
 0.94
chr4_90757689_90758348 0.10 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
 109
 0.84
chr10_99344095_99344388 0.10 PI4K2A
 Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
 110
 0.53
chr19_47991140_47991431 0.10 NAPA-AS1
 NAPA antisense RNA 1
 3720
 0.15
chr3_38325709_38325860 0.10 SLC22A14
 solute carrier family 22, member 14
 1995
 0.29
chr3_184286341_184286629 0.10 EPHB3
 EPH receptor B3
 6913
 0.2
chr16_2204070_2204407 0.10 ENSG00000206630
 .
 868
 0.23
chr4_7907648_7907905 0.10 AC097381.1
32952
 0.16
chr22_20790240_20790391 0.10 SCARF2
 scavenger receptor class F, member 2
 1797
 0.22
chr2_132430511_132430704 0.10 C2orf27A
 chromosome 2 open reading frame 27A
 49341
 0.15
chr9_130640034_130640202 0.10 AK1
 adenylate kinase 1
 96
 0.92
chr19_13734648_13734872 0.10 CACNA1A
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 44
 0.98
chr5_52105955_52106201 0.10 CTD-2288O8.1
22218
 0.18
chr1_84158363_84158987 0.10 ENSG00000223231
 .
 100885
 0.09
chr1_157963513_157964097 0.09 KIRREL
 kin of IRRE like (Drosophila)
 370
 0.89
chr6_158478262_158478415 0.09 SYNJ2
 synaptojanin 2
 20374
 0.19
chr12_49183193_49183344 0.09 ADCY6
 adenylate cyclase 6
 448
 0.69
chr4_170192362_170192994 0.09 SH3RF1
 SH3 domain containing ring finger 1
 422
 0.9
chr7_11579827_11580194 0.09 AC004160.4
133428
 0.05
chr10_79470838_79471281 0.09 ENSG00000199664
 .
 65754
 0.1
chr5_79866210_79866442 0.09 ANKRD34B
 ankyrin repeat domain 34B
 19
 0.98
chr9_137236302_137236526 0.09 RXRA
 retinoid X receptor, alpha
 17988
 0.22
chr10_43573048_43573466 0.09 RET
 ret proto-oncogene
 730
 0.74
chr20_50417404_50418104 0.09 SALL4
 spalt-like transcription factor 4
 1193
 0.55
chr19_47522872_47523023 0.09 NPAS1
 neuronal PAS domain protein 1
 130
 0.96
chr19_18521360_18521522 0.09 ENSG00000221167
 .
 849
 0.39
chr13_110959773_110960124 0.09 COL4A2
 collagen, type IV, alpha 2
 334
 0.6
chr13_44730017_44730207 0.09 SMIM2-IT1
 SMIM2 intronic transcript 1 (non-protein coding)
 2246
 0.3
chr1_1291746_1291897 0.09 MXRA8
 matrix-remodelling associated 8
 2094
 0.12
chr2_10540557_10540762 0.09 HPCAL1
 hippocalcin-like 1
 19488
 0.18
chr8_687260_687856 0.09 ERICH1-AS1
 ERICH1 antisense RNA 1
 93
 0.97
chr19_45146992_45147170 0.09 PVR
 poliovirus receptor
 17
 0.97
chr17_76921771_76922019 0.09 TIMP2
 TIMP metallopeptidase inhibitor 2
 426
 0.79

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF423

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0071605 monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.3 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines