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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for ZNF711_TFAP2A_TFAP2D

Z-value: 11.68

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Transcription factors associated with ZNF711_TFAP2A_TFAP2D

Gene Symbol	Gene ID	Gene Info
ZNF711 Ensembl NCBI GeneCards UniProt	ENSG00000147180.12	zinc finger protein 711
TFAP2A Ensembl NCBI GeneCards UniProt	ENSG00000137203.6	transcription factor AP-2 alpha
TFAP2D Ensembl NCBI GeneCards UniProt	ENSG00000008197.4	transcription factor AP-2 delta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_10412096_10412574	TFAP2A	272	0.897679	0.85	3.8e-03	Click!
chr6_10399107_10399258	TFAP2A	5645	0.203615	0.80	1.0e-02	Click!
chr6_10412868_10413115	TFAP2A	121	0.952705	0.75	1.9e-02	Click!
chr6_10415425_10415576	TFAP2A	19	0.934692	-0.69	4.0e-02	Click!
chr6_10404110_10404446	TFAP2A	549	0.760953	0.61	8.3e-02	Click!
chr6_50680636_50680787	TFAP2D	830	0.765684	0.20	6.0e-01	Click!
chr6_50378521_50378672	TFAP2D	302945	0.012272	-0.07	8.6e-01	Click!
chr6_50383487_50383638	TFAP2D	297979	0.012679	0.03	9.5e-01	Click!
chrX_84499187_84500398	ZNF711	21	0.941167	0.34	3.7e-01	Click!
chrX_84498834_84499090	ZNF711	35	0.632213	0.16	6.9e-01	Click!
chrX_84498582_84498733	ZNF711	340	0.585159	-0.14	7.2e-01	Click!

Activity of the ZNF711_TFAP2A_TFAP2D motif across conditions

Conditions sorted by the z-value of the ZNF711_TFAP2A_TFAP2D motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_76123581_76124282	8.35	TMC6	transmembrane channel-like 6	780	0.49
chr2_162101279_162101855	7.74	AC009299.2		6106	0.21
chr12_124018329_124018683	7.08	RILPL1	Rab interacting lysosomal protein-like 1	241	0.89
chr1_26872331_26872899	6.69	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	272	0.88
chr9_134150778_134151758	6.44	FAM78A	family with sequence similarity 78, member A	666	0.69
chr1_26437710_26438043	6.39	PDIK1L	PDLIM1 interacting kinase 1 like	212	0.9
chr16_67063172_67063793	6.36	CBFB	core-binding factor, beta subunit	118	0.94
chr2_113190375_113190911	6.33	RGPD8	RANBP2-like and GRIP domain containing 8	453	0.86
chr17_80416602_80417044	6.11	NARF	nuclear prelamin A recognition factor	72	0.83
chr8_21777326_21777532	5.84	XPO7	exportin 7	161	0.95
chr2_136633640_136633978	5.70	MCM6	minichromosome maintenance complex component 6	187	0.95
chr11_67171589_67172183	5.63	TBC1D10C	TBC1 domain family, member 10C	226	0.8
chr11_62554197_62554732	5.57	RP11-727F15.12		207	0.63
chr9_134152676_134153362	5.57	FAM78A	family with sequence similarity 78, member A	1085	0.5
chr9_100745668_100746275	5.56	ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	328	0.85
chr20_50158730_50159057	5.48	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	365	0.92
chr1_55266396_55266946	5.47	TTC22	tetratricopeptide repeat domain 22	200	0.91
chr9_129484934_129485155	5.46	ENSG00000266403	.	4432	0.26
chr22_50050359_50050996	5.45	C22orf34	chromosome 22 open reading frame 34	401	0.87
chr17_56408975_56409725	5.43	MIR142	microRNA 142	519	0.63
chr6_33756412_33756901	5.37	LEMD2	LEM domain containing 2	49	0.97
chr19_796345_796959	5.29	PTBP1	polypyrimidine tract binding protein 1	423	0.68
chr19_8274217_8274814	5.29	CERS4	ceramide synthase 4	3	0.97
chr18_9614776_9615146	5.27	PPP4R1	protein phosphatase 4, regulatory subunit 1	68	0.97
chr15_43028751_43029277	5.26	CDAN1	codanin 1	238	0.94
chr9_140008700_140009150	5.24	DPP7	dipeptidyl-peptidase 7	231	0.78
chr2_134877876_134878476	5.23	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	423	0.87
chr22_50913109_50913431	5.20	SBF1	SET binding factor 1	101	0.92
chr1_6674280_6674659	5.19	KLHL21	kelch-like family member 21	151	0.86
chr1_206680885_206681199	5.00	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	163	0.93
chr19_3179462_3180177	5.00	S1PR4	sphingosine-1-phosphate receptor 4	1083	0.38
chrX_19905153_19905596	4.97	SH3KBP1	SH3-domain kinase binding protein 1	203	0.96
chr18_77159557_77160137	4.97	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	475	0.86
chr17_48943002_48943431	4.97	TOB1	transducer of ERBB2, 1	490	0.6
chr16_3014681_3015078	4.96	KREMEN2	kringle containing transmembrane protein 2	357	0.69
chr7_5436621_5436873	4.91	TNRC18	trinucleotide repeat containing 18	9087	0.16
chr15_75494605_75495154	4.86	C15orf39	chromosome 15 open reading frame 39	333	0.82
chr10_82214211_82214515	4.83	TSPAN14	tetraspanin 14	252	0.93
chr12_117536177_117536841	4.81	TESC	tescalcin	742	0.76
chr8_101321788_101322100	4.78	RNF19A	ring finger protein 19A, RBR E3 ubiquitin protein ligase	190	0.96
chr12_113494960_113495179	4.74	DTX1	deltex homolog 1 (Drosophila)	426	0.82
chr7_101460259_101460698	4.73	CUX1	cut-like homeobox 1	404	0.87
chr2_45975_46264	4.71	FAM110C	family with sequence similarity 110, member C	266	0.95
chr20_4803550_4804195	4.69	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	419	0.85
chr5_7869360_7869764	4.66	MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	210	0.71
chr22_50630477_50630948	4.66	RP3-402G11.25		119	0.86
chr16_9185604_9185758	4.61	C16orf72	chromosome 16 open reading frame 72	176	0.94
chr11_2323518_2323777	4.61	TSPAN32	tetraspanin 32	267	0.57
chr7_72935956_72936258	4.60	BAZ1B	bromodomain adjacent to zinc finger domain, 1B	495	0.75
chr15_77289158_77289399	4.56	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	1363	0.44
chr20_62272433_62273064	4.54	STMN3	stathmin-like 3	11371	0.09
chr2_98611816_98612023	4.49	TMEM131	transmembrane protein 131	435	0.89
chr7_30324618_30324897	4.48	ZNRF2	zinc and ring finger 2	834	0.64
chr21_46238108_46238576	4.48	SUMO3	small ubiquitin-like modifier 3	298	0.85
chr19_17439012_17439348	4.47	ANO8	anoctamin 8	6458	0.08
chr20_4802726_4803481	4.46	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	1188	0.5
chr14_65346567_65346953	4.44	SPTB	spectrin, beta, erythrocytic	159	0.94
chr18_3012840_3013077	4.43	LPIN2	lipin 2	355	0.86
chr3_50375104_50375696	4.43	RASSF1	Ras association (RalGDS/AF-6) domain family member 1	264	0.76
chr17_28706240_28706541	4.41	CPD	carboxypeptidase D	467	0.76
chr13_113864040_113864325	4.41	CUL4A	cullin 4A	324	0.79
chr1_234614585_234614936	4.38	TARBP1	TAR (HIV-1) RNA binding protein 1	89	0.98
chr16_9056918_9057158	4.36	USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	303	0.91
chr10_135089818_135090113	4.36	ADAM8	ADAM metallopeptidase domain 8	389	0.74
chr17_43299403_43299689	4.31	CTD-2020K17.1		43	0.75
chrX_3761532_3762024	4.31	RP11-706O15.1	HCG1981372, isoform CRA_c; Uncharacterized protein	120	0.98
chr16_81349076_81349337	4.30	GAN	gigaxonin	649	0.67
chr14_24605460_24605695	4.30	PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	141	0.86
chr14_104181272_104181674	4.29	XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	307	0.62
chr8_65710999_65711587	4.27	CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	25	0.99
chr9_114393597_114394006	4.27	DNAJC25	DnaJ (Hsp40) homolog, subfamily C , member 25	135	0.49
chr22_41697652_41698202	4.26	ZC3H7B	zinc finger CCCH-type containing 7B	401	0.79
chr15_52121866_52123371	4.25	TMOD3	tropomodulin 3 (ubiquitous)	791	0.61
chr8_146052287_146052584	4.24	ZNF7	zinc finger protein 7	414	0.75
chr9_139009603_139010211	4.24	C9orf69	chromosome 9 open reading frame 69	213	0.94
chr7_3083277_3083584	4.24	CARD11	caspase recruitment domain family, member 11	49	0.98
chr1_182360957_182361120	4.24	GLUL	glutamate-ammonia ligase	111	0.97
chr6_119399577_119399871	4.23	FAM184A	family with sequence similarity 184, member A	184	0.95
chr17_73874128_73874630	4.22	TRIM47	tripartite motif containing 47	102	0.91
chr10_35625988_35626510	4.22	CCNY	cyclin Y	447	0.7
chr2_24713646_24713947	4.21	NCOA1	nuclear receptor coactivator 1	1005	0.64
chr20_278292_278479	4.21	ZCCHC3	zinc finger, CCHC domain containing 3	648	0.6
chr22_50638721_50639285	4.20	RP3-402G11.26		27	0.84
chr2_8825543_8825998	4.20	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	3584	0.27
chr14_69282780_69283493	4.19	ZFP36L1	ZFP36 ring finger protein-like 1	19946	0.19
chr20_62369505_62369786	4.17	RP4-583P15.14		22	0.92
chr11_2324171_2324374	4.13	TSPAN32	tetraspanin 32	174	0.88
chr17_20945868_20946375	4.11	USP22	ubiquitin specific peptidase 22	231	0.93
chr7_149194315_149194584	4.11	ZNF746	zinc finger protein 746	375	0.89
chr17_2240971_2241301	4.10	SGSM2	small G protein signaling modulator 2	220	0.6
chr5_107717232_107717910	4.10	FBXL17	F-box and leucine-rich repeat protein 17	228	0.97
chr19_3136242_3137376	4.10	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	618	0.58
chr22_21056169_21056915	4.10	POM121L4P	POM121 transmembrane nucleoporin-like 4 pseudogene	12325	0.13
chr19_8510156_8510458	4.09	HNRNPM	heterogeneous nuclear ribonucleoprotein M	429	0.73
chr17_16256516_16256704	4.08	CENPV	centromere protein V	160	0.94
chr13_52377985_52378296	4.08	DHRS12	dehydrogenase/reductase (SDR family) member 12	94	0.76
chr17_73840046_73840332	4.07	UNC13D	unc-13 homolog D (C. elegans)	226	0.84
chr8_144952195_144952400	4.07	EPPK1	epiplakin 1	335	0.79
chr11_316138_316595	4.06	RP11-326C3.11		2274	0.11
chr14_102228260_102228519	4.06	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	152	0.95
chr22_25961017_25961859	4.04	ADRBK2	adrenergic, beta, receptor kinase 2	622	0.55
chr21_16437486_16437824	4.04	NRIP1	nuclear receptor interacting protein 1	334	0.93
chr2_10091040_10091475	4.04	GRHL1	grainyhead-like 1 (Drosophila)	535	0.79
chr11_68608574_68609035	4.03	CPT1A	carnitine palmitoyltransferase 1A (liver)	580	0.77
chr22_40057938_40058206	4.01	CACNA1I	calcium channel, voltage-dependent, T type, alpha 1I subunit	91314	0.07
chr2_223725769_223726044	4.00	ACSL3	acyl-CoA synthetase long-chain family member 3	162	0.97
chr12_120972117_120972563	3.99	COQ5	coenzyme Q5 homolog, methyltransferase (S. cerevisiae)	103	0.6
chr9_95570477_95570696	3.99	ANKRD19P	ankyrin repeat domain 19, pseudogene	1307	0.42
chr9_35829202_35829460	3.99	TMEM8B	transmembrane protein 8B	102	0.86
chr10_105726864_105727229	3.96	SLK	STE20-like kinase	87	0.97
chr19_2290091_2290388	3.96	LINGO3	leucine rich repeat and Ig domain containing 3	1784	0.18
chr1_41327679_41328070	3.94	CITED4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4	144	0.94
chr1_1564774_1565122	3.93	MIB2	mindbomb E3 ubiquitin protein ligase 2	1079	0.29
chr3_13056686_13056902	3.93	IQSEC1	IQ motif and Sec7 domain 1	28258	0.23
chr6_20402144_20402837	3.92	E2F3	E2F transcription factor 3	92	0.96
chr3_41240580_41240931	3.92	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	170	0.98
chr6_135503685_135504285	3.92	MYB	v-myb avian myeloblastosis viral oncogene homolog	1333	0.44
chr3_133969553_133969766	3.91	RYK	receptor-like tyrosine kinase	30	0.99
chr11_2324787_2325062	3.91	TSPAN32	tetraspanin 32	826	0.45
chr9_135038389_135038692	3.91	NTNG2	netrin G2	1206	0.56
chr19_13213099_13213611	3.90	LYL1	lymphoblastic leukemia derived sequence 1	326	0.79
chr20_43279687_43280217	3.89	ADA	adenosine deaminase	380	0.81
chr7_129251866_129252047	3.88	NRF1	nuclear respiratory factor 1	359	0.9
chr8_37699008_37699734	3.88	BRF2	BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit	7985	0.16
chr15_45694566_45695165	3.88	SPATA5L1	spermatogenesis associated 5-like 1	297	0.59
chr19_6481304_6482171	3.87	DENND1C	DENN/MADD domain containing 1C	27	0.95
chr8_143808632_143809054	3.87	THEM6	thioesterase superfamily member 6	222	0.45
chr17_76121987_76122243	3.87	TMC6	transmembrane channel-like 6	986	0.4
chr12_76477913_76478352	3.87	NAP1L1	nucleosome assembly protein 1-like 1	258	0.93
chr10_124134278_124134675	3.86	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	126	0.96
chr22_50242881_50243371	3.86	ZBED4	zinc finger, BED-type containing 4	4364	0.21
chr4_1796827_1797107	3.86	FGFR3	fibroblast growth factor receptor 3	1344	0.42
chr20_57224690_57225235	3.86	STX16	syntaxin 16	1366	0.39
chr16_2265076_2265283	3.85	PGP	phosphoglycolate phosphatase	371	0.61
chr17_76836765_76836916	3.85	USP36	ubiquitin specific peptidase 36	23	0.97
chr11_416834_417350	3.85	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	233	0.85
chr17_48227122_48227652	3.84	PPP1R9B	protein phosphatase 1, regulatory subunit 9B	490	0.64
chr9_35072054_35072271	3.84	VCP	valosin containing protein	151	0.91
chr6_3751810_3752094	3.84	PXDC1	PX domain containing 1	308	0.72
chr1_7831350_7831659	3.83	VAMP3	vesicle-associated membrane protein 3	175	0.93
chr19_12833178_12833372	3.82	TNPO2	transportin 2	64	0.92
chr1_153918834_153919140	3.82	DENND4B	DENN/MADD domain containing 4B	185	0.88
chr10_121485586_121485901	3.82	INPP5F	inositol polyphosphate-5-phosphatase F	134	0.97
chr17_56410108_56410593	3.81	MIR142	microRNA 142	481	0.66
chr11_57243949_57244502	3.81	RP11-624G17.3		782	0.45
chr11_73087458_73087910	3.81	RELT	RELT tumor necrosis factor receptor	29	0.97
chr7_138145136_138145700	3.81	TRIM24	tripartite motif containing 24	238	0.94
chr16_67571972_67572459	3.80	FAM65A	family with sequence similarity 65, member A	234	0.82
chr9_136150814_136151142	3.80	ENSG00000201843	.	26975	0.09
chr3_5229473_5230342	3.80	AC026202.1	Uncharacterized protein	75	0.56
chr22_17601691_17602165	3.79	CECR6	cat eye syndrome chromosome region, candidate 6	215	0.77
chr12_2904145_2904429	3.79	FKBP4	FK506 binding protein 4, 59kDa	168	0.92
chr3_25705652_25705988	3.78	TOP2B	topoisomerase (DNA) II beta 180kDa	32	0.93
chr4_1004642_1005092	3.78	FGFRL1	fibroblast growth factor receptor-like 1	743	0.56
chr14_91883760_91884222	3.78	CCDC88C	coiled-coil domain containing 88C	130	0.97
chr20_3026739_3027121	3.77	MRPS26	mitochondrial ribosomal protein S26	339	0.8
chr9_137217336_137217895	3.77	RXRA	retinoid X receptor, alpha	811	0.72
chr10_73847731_73848399	3.77	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	21	0.98
chr6_64282916_64283107	3.77	PTP4A1	protein tyrosine phosphatase type IVA, member 1	425	0.65
chr1_15736508_15737107	3.76	EFHD2	EF-hand domain family, member D2	46	0.97
chr3_122233391_122233733	3.76	KPNA1	karyopherin alpha 1 (importin alpha 5)	173	0.95
chr3_33155595_33155944	3.75	CRTAP	cartilage associated protein	223	0.91
chr5_74348957_74349108	3.75	GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	22308	0.25
chr11_65339892_65340265	3.74	FAM89B	family with sequence similarity 89, member B	79	0.91
chr5_102594552_102594973	3.74	C5orf30	chromosome 5 open reading frame 30	25	0.98
chr8_124553468_124553740	3.74	FBXO32	F-box protein 32	158	0.96
chr12_117536981_117537237	3.74	TESC	tescalcin	142	0.97
chr12_96793768_96794206	3.73	CDK17	cyclin-dependent kinase 17	135	0.96
chr8_146052992_146053214	3.73	ZNF7	zinc finger protein 7	100	0.94
chr19_54875923_54876565	3.73	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	170	0.91
chr1_35657917_35658364	3.72	SFPQ	splicing factor proline/glutamine-rich	609	0.7
chr14_77786841_77787155	3.71	POMT2	protein-O-mannosyltransferase 2	229	0.48
chr17_61777673_61777989	3.71	LIMD2	LIM domain containing 2	214	0.92
chr21_45661777_45662023	3.70	ICOSLG	inducible T-cell co-stimulator ligand	1051	0.37
chr17_263385_263906	3.70	AC108004.3		169	0.93
chr1_234744755_234744925	3.70	IRF2BP2	interferon regulatory factor 2 binding protein 2	431	0.8
chr3_152880165_152880606	3.69	RAP2B	RAP2B, member of RAS oncogene family	356	0.75
chr9_140117422_140117971	3.69	C9orf169	chromosome 9 open reading frame 169	1391	0.14
chr5_175964065_175964400	3.69	RNF44	ring finger protein 44	189	0.91
chr22_37881738_37882044	3.69	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	534	0.71
chr19_17515989_17516450	3.68	BST2	bone marrow stromal cell antigen 2	238	0.54
chr10_135090163_135090314	3.68	ADAM8	ADAM metallopeptidase domain 8	116	0.93
chr6_35265630_35266434	3.68	DEF6	differentially expressed in FDCP 6 homolog (mouse)	403	0.84
chr3_197354198_197354750	3.68	AC024560.3		245	0.93
chr19_16254556_16255035	3.67	HSH2D	hematopoietic SH2 domain containing	249	0.88
chr2_202507510_202508172	3.67	TMEM237	transmembrane protein 237	174	0.94
chr17_80170886_80171308	3.67	CCDC57	coiled-coil domain containing 57	408	0.65
chr17_55162734_55163425	3.66	AKAP1	A kinase (PRKA) anchor protein 1	1	0.98
chr17_74448855_74449165	3.66	UBE2O	ubiquitin-conjugating enzyme E2O	278	0.6
chr17_54910886_54911269	3.65	C17orf67	chromosome 17 open reading frame 67	179	0.72
chrX_39957338_39957651	3.65	BCOR	BCL6 corepressor	838	0.77
chr17_7141304_7141505	3.65	PHF23	PHD finger protein 23	86	0.9
chr1_20960010_20960411	3.65	PINK1	PTEN induced putative kinase 1	262	0.91
chr16_2826706_2827078	3.64	TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	236	0.82
chrX_3799973_3800438	3.64	RP11-706O15.1	HCG1981372, isoform CRA_c; Uncharacterized protein	38307	0.22
chr7_1543718_1544009	3.64	INTS1	integrator complex subunit 1	140	0.94
chr15_29131227_29131499	3.63	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2	54	0.98
chr9_99180680_99180947	3.63	ZNF367	zinc finger protein 367	202	0.95
chr19_2083107_2083981	3.62	MOB3A	MOB kinase activator 3A	1847	0.21
chrX_9433454_9434167	3.62	TBL1X	transducin (beta)-like 1X-linked	476	0.9

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF711_TFAP2A_TFAP2D

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.0	20.9	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
6.5	19.5	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
5.3	15.8	GO:0035405	histone-threonine phosphorylation(GO:0035405)
4.9	14.8	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
4.5	22.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
4.5	17.8	GO:0048541	Peyer's patch development(GO:0048541)
4.4	17.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
4.4	4.4	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
4.3	12.9	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
4.1	20.7	GO:0007386	compartment pattern specification(GO:0007386)
4.1	12.4	GO:0061526	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
4.0	16.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
3.9	19.5	GO:0043984	histone H4-K16 acetylation(GO:0043984)
3.9	7.8	GO:0030223	neutrophil differentiation(GO:0030223)
3.9	19.4	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
3.8	11.5	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
3.8	15.3	GO:0034063	stress granule assembly(GO:0034063)
3.8	3.8	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
3.8	7.5	GO:0070669	response to interleukin-2(GO:0070669)
3.7	14.8	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
3.7	11.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
3.6	7.3	GO:0072216	positive regulation of metanephros development(GO:0072216)
3.6	3.6	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
3.6	7.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
3.6	10.8	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
3.4	10.2	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
3.4	10.2	GO:0010815	bradykinin catabolic process(GO:0010815)
3.3	13.4	GO:0019322	pentose biosynthetic process(GO:0019322)
3.3	19.9	GO:0010452	histone H3-K36 methylation(GO:0010452)
3.3	6.6	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
3.3	9.9	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
3.2	3.2	GO:0032649	interferon-gamma production(GO:0032609) regulation of interferon-gamma production(GO:0032649)
3.2	9.7	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
3.2	6.4	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
3.2	6.4	GO:0000212	meiotic spindle organization(GO:0000212)
3.2	6.4	GO:1901419	regulation of response to alcohol(GO:1901419)
3.2	3.2	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
3.2	3.2	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
3.1	6.2	GO:0022038	corpus callosum development(GO:0022038)
3.1	27.9	GO:0002467	germinal center formation(GO:0002467)
3.1	18.5	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
3.1	12.3	GO:0000089	mitotic metaphase(GO:0000089)
3.0	3.0	GO:0051014	actin filament severing(GO:0051014)
3.0	9.1	GO:0070670	response to interleukin-4(GO:0070670)
3.0	3.0	GO:0051297	microtubule organizing center organization(GO:0031023) centrosome organization(GO:0051297)
3.0	12.0	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
3.0	3.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
3.0	50.4	GO:0046834	lipid phosphorylation(GO:0046834)
3.0	11.9	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
2.9	8.8	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
2.9	8.8	GO:0001821	histamine secretion(GO:0001821)
2.9	5.9	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
2.9	11.7	GO:0040023	establishment of nucleus localization(GO:0040023)
2.9	45.7	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
2.9	11.4	GO:0034629	cellular protein complex localization(GO:0034629)
2.9	2.9	GO:0032075	positive regulation of nuclease activity(GO:0032075)
2.8	8.5	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
2.8	14.2	GO:0014010	Schwann cell proliferation(GO:0014010)
2.8	8.4	GO:0034720	histone H3-K4 demethylation(GO:0034720)
2.8	2.8	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
2.8	14.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
2.8	11.2	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
2.8	2.8	GO:0032769	negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001)
2.7	16.5	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
2.7	5.4	GO:0050765	negative regulation of phagocytosis(GO:0050765)
2.7	2.7	GO:0006011	UDP-glucose metabolic process(GO:0006011)
2.7	8.0	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
2.6	5.3	GO:0010761	fibroblast migration(GO:0010761)
2.6	2.6	GO:0060712	spongiotrophoblast layer development(GO:0060712)
2.6	7.9	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
2.6	10.5	GO:0019388	galactose catabolic process(GO:0019388)
2.6	10.5	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
2.6	2.6	GO:0005997	xylulose metabolic process(GO:0005997)
2.6	2.6	GO:0000279	M phase(GO:0000279)
2.6	2.6	GO:0032006	regulation of TOR signaling(GO:0032006)
2.6	5.2	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
2.6	10.3	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
2.6	2.6	GO:0006642	triglyceride mobilization(GO:0006642)
2.6	2.6	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
2.6	7.7	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
2.6	12.8	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
2.6	20.5	GO:0051489	regulation of filopodium assembly(GO:0051489)
2.6	7.7	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
2.5	7.4	GO:0032928	regulation of superoxide anion generation(GO:0032928)
2.5	7.4	GO:0022417	protein maturation by protein folding(GO:0022417)
2.5	7.4	GO:0043276	anoikis(GO:0043276)
2.5	2.5	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
2.4	4.9	GO:0007405	neuroblast proliferation(GO:0007405)
2.4	4.9	GO:0007144	female meiosis I(GO:0007144)
2.4	2.4	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
2.4	9.7	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
2.4	7.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
2.4	7.2	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
2.4	12.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
2.4	7.2	GO:0033522	histone H2A ubiquitination(GO:0033522)
2.4	7.2	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
2.4	16.8	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
2.4	4.8	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
2.4	2.4	GO:0006549	isoleucine metabolic process(GO:0006549)
2.4	30.9	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
2.4	4.7	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
2.4	7.1	GO:0006167	AMP biosynthetic process(GO:0006167)
2.4	18.8	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
2.4	2.4	GO:0061154	endothelial tube morphogenesis(GO:0061154)
2.4	11.8	GO:0007256	activation of JNKK activity(GO:0007256)
2.3	4.7	GO:0001543	ovarian follicle rupture(GO:0001543)
2.3	7.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
2.3	2.3	GO:0051340	regulation of ligase activity(GO:0051340)
2.3	21.0	GO:0051322	anaphase(GO:0051322)
2.3	7.0	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
2.3	7.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
2.3	11.6	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
2.3	7.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
2.3	9.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
2.3	6.9	GO:0001921	positive regulation of receptor recycling(GO:0001921)
2.3	6.9	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
2.3	2.3	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
2.3	6.8	GO:0019372	lipoxygenase pathway(GO:0019372)
2.3	4.5	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
2.3	6.8	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
2.3	13.6	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
2.3	15.8	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
2.3	4.5	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
2.3	11.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
2.3	6.8	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
2.2	4.5	GO:0035246	peptidyl-arginine methylation(GO:0018216) peptidyl-arginine N-methylation(GO:0035246)
2.2	11.2	GO:0032495	response to muramyl dipeptide(GO:0032495)
2.2	6.7	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
2.2	6.7	GO:0046548	retinal rod cell development(GO:0046548)
2.2	2.2	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
2.2	4.5	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
2.2	11.1	GO:0051382	kinetochore assembly(GO:0051382)
2.2	2.2	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
2.2	8.8	GO:0032486	Rap protein signal transduction(GO:0032486)
2.2	11.0	GO:0071545	inositol phosphate catabolic process(GO:0071545)
2.2	6.6	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
2.2	6.6	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
2.2	4.4	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
2.2	8.8	GO:0051642	centrosome localization(GO:0051642)
2.2	8.8	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
2.2	11.0	GO:0045793	positive regulation of cell size(GO:0045793)
2.2	8.8	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
2.2	17.5	GO:0007172	signal complex assembly(GO:0007172)
2.2	48.1	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
2.2	6.6	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
2.2	8.7	GO:0051570	negative regulation of histone methylation(GO:0031061) regulation of histone H3-K9 methylation(GO:0051570)
2.2	6.5	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
2.2	4.3	GO:0090200	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
2.1	12.9	GO:0045059	positive thymic T cell selection(GO:0045059)
2.1	21.2	GO:0007020	microtubule nucleation(GO:0007020)
2.1	8.5	GO:0042416	dopamine biosynthetic process(GO:0042416)
2.1	6.3	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
2.1	8.4	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
2.1	4.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
2.1	8.4	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
2.1	2.1	GO:0001743	optic placode formation(GO:0001743)
2.1	18.7	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
2.1	12.5	GO:0045910	negative regulation of DNA recombination(GO:0045910)
2.1	10.3	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
2.1	4.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
2.1	24.7	GO:0032008	positive regulation of TOR signaling(GO:0032008)
2.1	6.2	GO:0032203	telomere formation via telomerase(GO:0032203)
2.1	16.4	GO:0006013	mannose metabolic process(GO:0006013)
2.0	2.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
2.0	6.1	GO:0016559	peroxisome fission(GO:0016559)
2.0	14.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
2.0	14.1	GO:0006265	DNA topological change(GO:0006265)
2.0	2.0	GO:0051974	negative regulation of telomerase activity(GO:0051974)
2.0	2.0	GO:0006906	vesicle fusion(GO:0006906)
2.0	2.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
2.0	8.0	GO:0060539	diaphragm development(GO:0060539)
2.0	6.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
2.0	2.0	GO:0070527	platelet aggregation(GO:0070527)
2.0	4.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.0	13.9	GO:0002063	chondrocyte development(GO:0002063)
2.0	5.9	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
2.0	7.9	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
2.0	2.0	GO:0090311	regulation of protein deacetylation(GO:0090311)
2.0	5.9	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
2.0	7.9	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
2.0	21.7	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
2.0	5.9	GO:0043173	nucleotide salvage(GO:0043173)
2.0	5.9	GO:0032025	response to cobalt ion(GO:0032025)
2.0	5.9	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
2.0	3.9	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
2.0	5.9	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
2.0	2.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
1.9	7.8	GO:0046951	ketone body biosynthetic process(GO:0046951)
1.9	9.7	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
1.9	11.6	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
1.9	1.9	GO:0008298	intracellular mRNA localization(GO:0008298)
1.9	3.8	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
1.9	9.6	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
1.9	1.9	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
1.9	11.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
1.9	7.6	GO:0043985	histone H4-R3 methylation(GO:0043985)
1.9	3.8	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
1.9	5.7	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
1.9	1.9	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
1.9	13.2	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
1.9	5.6	GO:0035067	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
1.9	1.9	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
1.9	22.5	GO:0006378	mRNA polyadenylation(GO:0006378)
1.9	3.7	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985)
1.9	9.3	GO:0000729	DNA double-strand break processing(GO:0000729)
1.9	1.9	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
1.9	5.6	GO:1903504	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
1.9	9.3	GO:0006102	isocitrate metabolic process(GO:0006102)
1.8	3.7	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.8	3.7	GO:0042733	embryonic digit morphogenesis(GO:0042733)
1.8	1.8	GO:0003197	endocardial cushion development(GO:0003197)
1.8	3.7	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
1.8	1.8	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.8	3.7	GO:0032060	bleb assembly(GO:0032060)
1.8	1.8	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
1.8	5.5	GO:0032801	receptor catabolic process(GO:0032801)
1.8	21.8	GO:0016925	protein sumoylation(GO:0016925)
1.8	3.6	GO:0061008	liver development(GO:0001889) hepaticobiliary system development(GO:0061008)
1.8	14.5	GO:0034311	diol metabolic process(GO:0034311)
1.8	7.2	GO:0015853	adenine transport(GO:0015853)
1.8	1.8	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
1.8	5.4	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
1.8	1.8	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
1.8	1.8	GO:0060449	bud elongation involved in lung branching(GO:0060449)
1.8	17.8	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
1.8	1.8	GO:0016572	histone phosphorylation(GO:0016572)
1.8	1.8	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
1.8	5.3	GO:0006266	DNA ligation(GO:0006266)
1.8	5.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
1.8	3.5	GO:0033622	integrin activation(GO:0033622)
1.8	95.5	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
1.8	8.8	GO:0039703	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
1.8	1.8	GO:0006290	pyrimidine dimer repair(GO:0006290)
1.8	5.3	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
1.8	22.9	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
1.8	15.8	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
1.8	5.3	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
1.8	14.0	GO:0006878	cellular copper ion homeostasis(GO:0006878)
1.7	3.5	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
1.7	5.2	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
1.7	8.7	GO:0006983	ER overload response(GO:0006983)
1.7	10.5	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
1.7	1.7	GO:0051145	smooth muscle cell differentiation(GO:0051145)
1.7	8.6	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.7	3.5	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
1.7	6.9	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
1.7	29.4	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
1.7	6.9	GO:0006999	nuclear pore organization(GO:0006999)
1.7	5.2	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
1.7	3.4	GO:0042159	lipoprotein catabolic process(GO:0042159)
1.7	5.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
1.7	5.1	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
1.7	6.8	GO:0010508	positive regulation of autophagy(GO:0010508)
1.7	23.7	GO:0016578	histone deubiquitination(GO:0016578)
1.7	5.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
1.7	15.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
1.7	3.4	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.7	1.7	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
1.7	5.0	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
1.7	15.1	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
1.7	3.4	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
1.7	3.3	GO:0072676	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
1.7	1.7	GO:0060119	inner ear receptor cell development(GO:0060119)
1.7	18.3	GO:0016180	snRNA processing(GO:0016180)
1.7	5.0	GO:1901215	negative regulation of neuron apoptotic process(GO:0043524) negative regulation of neuron death(GO:1901215)
1.7	11.6	GO:0014037	Schwann cell differentiation(GO:0014037)
1.7	5.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
1.7	1.7	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
1.7	1.7	GO:0002679	respiratory burst involved in defense response(GO:0002679)
1.7	1.7	GO:0042100	B cell proliferation(GO:0042100)
1.7	77.8	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
1.6	8.2	GO:0008089	anterograde axonal transport(GO:0008089)
1.6	1.6	GO:0032508	DNA duplex unwinding(GO:0032508)
1.6	11.5	GO:0015780	nucleotide-sugar transport(GO:0015780)
1.6	3.3	GO:0045071	negative regulation of viral genome replication(GO:0045071)
1.6	8.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.6	8.2	GO:0001881	receptor recycling(GO:0001881)
1.6	4.9	GO:0070634	transepithelial ammonium transport(GO:0070634)
1.6	11.5	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
1.6	6.5	GO:0019985	translesion synthesis(GO:0019985)
1.6	8.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.6	6.5	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
1.6	1.6	GO:0009299	mRNA transcription(GO:0009299)
1.6	1.6	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
1.6	6.4	GO:0000076	DNA replication checkpoint(GO:0000076)
1.6	1.6	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
1.6	12.8	GO:0034976	response to endoplasmic reticulum stress(GO:0034976)
1.6	3.2	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
1.6	4.8	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
1.6	3.2	GO:0032202	telomere assembly(GO:0032202)
1.6	4.8	GO:0018094	protein polyglycylation(GO:0018094)
1.6	33.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
1.6	4.7	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
1.6	4.7	GO:0042149	cellular response to glucose starvation(GO:0042149)
1.6	3.2	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.6	6.3	GO:0006689	ganglioside catabolic process(GO:0006689)
1.6	15.7	GO:0016558	protein import into peroxisome matrix(GO:0016558)
1.6	9.4	GO:0000183	chromatin silencing at rDNA(GO:0000183)
1.6	4.7	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.6	6.3	GO:0032329	serine transport(GO:0032329)
1.6	4.7	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
1.6	7.8	GO:0045116	protein neddylation(GO:0045116)
1.6	6.2	GO:0034453	microtubule anchoring(GO:0034453)
1.6	34.2	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
1.6	1.6	GO:0050773	regulation of dendrite development(GO:0050773)
1.6	6.2	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
1.5	3.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.5	1.5	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
1.5	1.5	GO:0046134	pyrimidine nucleoside biosynthetic process(GO:0046134)
1.5	1.5	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
1.5	3.1	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
1.5	1.5	GO:0060972	left/right pattern formation(GO:0060972)
1.5	3.1	GO:0051665	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
1.5	3.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
1.5	6.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
1.5	1.5	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
1.5	6.1	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.5	3.1	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
1.5	4.6	GO:0071436	sodium ion export(GO:0071436)
1.5	3.1	GO:0048291	isotype switching to IgG isotypes(GO:0048291)
1.5	6.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
1.5	9.1	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
1.5	59.3	GO:0030521	androgen receptor signaling pathway(GO:0030521)
1.5	4.6	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
1.5	10.6	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
1.5	1.5	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
1.5	69.7	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
1.5	16.6	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
1.5	6.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
1.5	13.6	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
1.5	1.5	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
1.5	9.0	GO:0006984	ER-nucleus signaling pathway(GO:0006984)
1.5	3.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.5	10.5	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
1.5	3.0	GO:1903332	regulation of protein folding(GO:1903332)
1.5	4.5	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
1.5	28.3	GO:0006611	protein export from nucleus(GO:0006611)
1.5	4.5	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
1.5	7.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.5	5.9	GO:0006564	L-serine biosynthetic process(GO:0006564)
1.5	3.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
1.5	7.4	GO:0001866	NK T cell proliferation(GO:0001866)
1.5	1.5	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
1.5	4.4	GO:0032007	negative regulation of TOR signaling(GO:0032007)
1.5	5.9	GO:0043248	proteasome assembly(GO:0043248)
1.5	1.5	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
1.5	2.9	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
1.5	1.5	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
1.5	1.5	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
1.5	7.3	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
1.5	30.7	GO:0006270	DNA replication initiation(GO:0006270)
1.5	2.9	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
1.5	10.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
1.5	2.9	GO:0045351	type I interferon biosynthetic process(GO:0045351)
1.5	13.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
1.5	5.8	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
1.5	5.8	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
1.5	4.4	GO:0000239	pachytene(GO:0000239)
1.4	1.4	GO:2000041	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.4	4.3	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
1.4	4.3	GO:0015801	aromatic amino acid transport(GO:0015801)
1.4	10.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
1.4	1.4	GO:0007100	mitotic centrosome separation(GO:0007100)
1.4	8.7	GO:0016584	nucleosome positioning(GO:0016584)
1.4	30.3	GO:0043966	histone H3 acetylation(GO:0043966)
1.4	2.9	GO:1901862	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle organ development(GO:0048635) negative regulation of muscle tissue development(GO:1901862)
1.4	2.9	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
1.4	2.9	GO:0070837	dehydroascorbic acid transport(GO:0070837)
1.4	2.9	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
1.4	7.1	GO:0042989	sequestering of actin monomers(GO:0042989)
1.4	4.3	GO:0006448	regulation of translational elongation(GO:0006448)
1.4	11.4	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
1.4	1.4	GO:0032682	negative regulation of chemokine production(GO:0032682)
1.4	7.1	GO:0030851	granulocyte differentiation(GO:0030851)
1.4	2.8	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
1.4	4.3	GO:0051409	response to nitrosative stress(GO:0051409)
1.4	5.7	GO:1900274	positive regulation of phospholipase C activity(GO:0010863) regulation of phospholipase C activity(GO:1900274)
1.4	1.4	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
1.4	8.5	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
1.4	1.4	GO:0001955	blood vessel maturation(GO:0001955)
1.4	7.0	GO:0042832	defense response to protozoan(GO:0042832)
1.4	11.3	GO:0044349	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
1.4	2.8	GO:0097576	vacuole fusion(GO:0097576)
1.4	1.4	GO:0015851	nucleobase transport(GO:0015851)
1.4	2.8	GO:0002274	myeloid leukocyte activation(GO:0002274)
1.4	26.6	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
1.4	11.2	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
1.4	2.8	GO:0019042	viral latency(GO:0019042)
1.4	2.8	GO:0030011	maintenance of cell polarity(GO:0030011)
1.4	1.4	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
1.4	9.7	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
1.4	6.9	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
1.4	13.8	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
1.4	4.1	GO:0010447	response to acidic pH(GO:0010447)
1.4	45.5	GO:0050434	positive regulation of viral transcription(GO:0050434)
1.4	4.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
1.4	1.4	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
1.4	1.4	GO:1902692	regulation of neuroblast proliferation(GO:1902692)
1.4	20.6	GO:0016574	histone ubiquitination(GO:0016574)
1.4	9.6	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
1.4	25.9	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
1.4	13.6	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
1.4	2.7	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.4	19.0	GO:0043484	regulation of RNA splicing(GO:0043484)
1.4	4.1	GO:0031297	replication fork processing(GO:0031297)
1.4	8.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
1.4	2.7	GO:2000816	negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) mitotic spindle checkpoint(GO:0071174) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100) negative regulation of mitotic sister chromatid separation(GO:2000816)
1.3	9.4	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.3	6.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
1.3	4.0	GO:0030091	protein repair(GO:0030091)
1.3	4.0	GO:0009301	snRNA transcription(GO:0009301)
1.3	24.1	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
1.3	2.7	GO:0034339	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
1.3	14.7	GO:0031581	hemidesmosome assembly(GO:0031581)
1.3	6.7	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
1.3	4.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
1.3	4.0	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
1.3	1.3	GO:0051775	response to redox state(GO:0051775)
1.3	5.3	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
1.3	6.6	GO:0006561	proline biosynthetic process(GO:0006561)
1.3	18.4	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
1.3	2.6	GO:0033598	mammary gland epithelial cell proliferation(GO:0033598)
1.3	1.3	GO:0016458	gene silencing(GO:0016458)
1.3	2.6	GO:0045638	negative regulation of myeloid cell differentiation(GO:0045638)
1.3	3.9	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.3	3.9	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
1.3	1.3	GO:0048041	cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
1.3	1.3	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
1.3	63.6	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
1.3	3.9	GO:0046479	glycosylceramide catabolic process(GO:0046477) glycosphingolipid catabolic process(GO:0046479)
1.3	1.3	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
1.3	3.9	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
1.3	3.9	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
1.3	5.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
1.3	25.8	GO:0030183	B cell differentiation(GO:0030183)
1.3	1.3	GO:0043174	nucleoside salvage(GO:0043174)
1.3	9.0	GO:0006376	mRNA splice site selection(GO:0006376)
1.3	2.6	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
1.3	2.6	GO:0043388	positive regulation of DNA binding(GO:0043388)
1.3	1.3	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
1.3	5.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
1.3	6.4	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
1.3	2.6	GO:0007021	tubulin complex assembly(GO:0007021)
1.3	2.5	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
1.3	21.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
1.3	7.6	GO:0019059	obsolete initiation of viral infection(GO:0019059)
1.3	2.5	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
1.3	224.9	GO:0016568	chromatin modification(GO:0016568)
1.3	6.3	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.3	3.8	GO:0032922	circadian regulation of gene expression(GO:0032922)
1.3	3.8	GO:2000171	negative regulation of dendrite development(GO:2000171)
1.3	5.0	GO:0002098	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
1.3	1.3	GO:0048318	axial mesoderm development(GO:0048318)
1.3	2.5	GO:0051000	positive regulation of nitric-oxide synthase activity(GO:0051000)
1.3	3.8	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
1.2	1.2	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
1.2	3.7	GO:0045683	negative regulation of epidermis development(GO:0045683)
1.2	1.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
1.2	3.7	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
1.2	7.4	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
1.2	3.7	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
1.2	64.2	GO:0006413	translational initiation(GO:0006413)
1.2	18.5	GO:0035384	thioester biosynthetic process(GO:0035384) acyl-CoA biosynthetic process(GO:0071616)
1.2	1.2	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
1.2	8.6	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
1.2	3.7	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
1.2	1.2	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
1.2	12.2	GO:0009084	glutamine family amino acid biosynthetic process(GO:0009084)
1.2	4.9	GO:0006379	mRNA cleavage(GO:0006379)
1.2	6.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
1.2	1.2	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988) regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
1.2	1.2	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
1.2	2.4	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
1.2	3.6	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
1.2	2.4	GO:0072659	protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
1.2	2.4	GO:0045010	actin nucleation(GO:0045010)
1.2	2.4	GO:0051168	nuclear export(GO:0051168)
1.2	2.4	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
1.2	2.4	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
1.2	14.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
1.2	17.9	GO:0030593	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
1.2	11.9	GO:0042770	signal transduction in response to DNA damage(GO:0042770)
1.2	82.0	GO:0050658	nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
1.2	4.7	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
1.2	2.4	GO:0034505	tooth mineralization(GO:0034505)
1.2	8.3	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
1.2	3.5	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
1.2	1.2	GO:0016075	rRNA catabolic process(GO:0016075)
1.2	17.6	GO:0019079	viral genome replication(GO:0019079)
1.2	2.3	GO:0001709	cell fate determination(GO:0001709)
1.2	1.2	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
1.2	2.3	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
1.2	5.8	GO:0031648	protein destabilization(GO:0031648)
1.2	38.5	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
1.2	9.3	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
1.2	4.7	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.2	12.8	GO:0000722	telomere maintenance via recombination(GO:0000722)
1.2	9.3	GO:0006282	regulation of DNA repair(GO:0006282)
1.2	3.5	GO:0007000	nucleolus organization(GO:0007000)
1.2	1.2	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
1.2	20.9	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
1.2	13.9	GO:0007076	mitotic chromosome condensation(GO:0007076)
1.2	2.3	GO:0042420	dopamine catabolic process(GO:0042420)
1.2	2.3	GO:0046519	sphingoid metabolic process(GO:0046519)
1.2	10.4	GO:0051865	protein autoubiquitination(GO:0051865)
1.2	4.6	GO:0016553	base conversion or substitution editing(GO:0016553)
1.2	3.5	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
1.2	1.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
1.2	2.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
1.1	17.2	GO:0006289	nucleotide-excision repair(GO:0006289)
1.1	114.9	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
1.1	20.7	GO:0031396	regulation of protein ubiquitination(GO:0031396)
1.1	3.4	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.1	4.6	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
1.1	3.4	GO:0032091	negative regulation of protein binding(GO:0032091)
1.1	3.4	GO:0035434	copper ion transmembrane transport(GO:0035434)
1.1	16.0	GO:0016236	macroautophagy(GO:0016236)
1.1	2.3	GO:0006390	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
1.1	1.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
1.1	6.8	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
1.1	12.5	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.1	28.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
1.1	32.9	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
1.1	3.4	GO:0048625	myoblast fate commitment(GO:0048625)
1.1	3.4	GO:0006678	glucosylceramide metabolic process(GO:0006678)
1.1	1.1	GO:0018343	protein farnesylation(GO:0018343)
1.1	1.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
1.1	12.4	GO:0007006	mitochondrial membrane organization(GO:0007006)
1.1	1.1	GO:0006491	N-glycan processing(GO:0006491)
1.1	13.5	GO:0043526	obsolete neuroprotection(GO:0043526)
1.1	10.1	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
1.1	1.1	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
1.1	2.3	GO:0006998	nuclear envelope organization(GO:0006998)
1.1	1.1	GO:0006612	protein targeting to membrane(GO:0006612)
1.1	4.5	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
1.1	3.4	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
1.1	3.4	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
1.1	20.1	GO:0006471	protein ADP-ribosylation(GO:0006471)
1.1	5.6	GO:0002281	macrophage activation involved in immune response(GO:0002281)
1.1	1.1	GO:0070672	response to interleukin-15(GO:0070672)
1.1	6.7	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
1.1	2.2	GO:1902099	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
1.1	5.6	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
1.1	1.1	GO:0016199	axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
1.1	14.4	GO:0000084	mitotic S phase(GO:0000084)
1.1	5.6	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
1.1	17.8	GO:0006672	ceramide metabolic process(GO:0006672)
1.1	3.3	GO:0002002	regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
1.1	10.0	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
1.1	7.7	GO:0006105	succinate metabolic process(GO:0006105)
1.1	1.1	GO:0035725	sodium ion transmembrane transport(GO:0035725)
1.1	2.2	GO:0055089	fatty acid homeostasis(GO:0055089)
1.1	39.6	GO:0030833	regulation of actin filament polymerization(GO:0030833)
1.1	1.1	GO:0014897	cardiac muscle hypertrophy(GO:0003300) striated muscle hypertrophy(GO:0014897)
1.1	11.0	GO:0008380	RNA splicing(GO:0008380)
1.1	5.5	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
1.1	81.9	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
1.1	3.3	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
1.1	3.3	GO:0050931	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
1.1	1.1	GO:0010040	response to iron(II) ion(GO:0010040)
1.1	5.4	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
1.1	1.1	GO:0006536	glutamate metabolic process(GO:0006536)
1.1	6.5	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
1.1	13.0	GO:0007052	mitotic spindle organization(GO:0007052)
1.1	3.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
1.1	5.4	GO:0009304	tRNA transcription(GO:0009304)
1.1	9.7	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
1.1	1.1	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516)
1.1	4.3	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
1.1	2.1	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
1.1	18.0	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.1	3.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
1.1	3.2	GO:1903307	positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306) positive regulation of regulated secretory pathway(GO:1903307)
1.1	1.1	GO:0050691	regulation of defense response to virus by host(GO:0050691)
1.1	5.3	GO:0006857	oligopeptide transport(GO:0006857)
1.1	6.3	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
1.1	5.3	GO:0050684	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
1.1	1.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
1.1	2.1	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
1.1	1.1	GO:0031338	regulation of vesicle fusion(GO:0031338)
1.1	5.3	GO:0046039	GTP metabolic process(GO:0046039)
1.1	2.1	GO:0032925	regulation of activin receptor signaling pathway(GO:0032925)
1.0	2.1	GO:0007549	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
1.0	3.1	GO:0008088	axo-dendritic transport(GO:0008088)
1.0	1.0	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
1.0	2.1	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
1.0	8.3	GO:0032456	endocytic recycling(GO:0032456)
1.0	3.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
1.0	2.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
1.0	2.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
1.0	1.0	GO:0008216	spermidine metabolic process(GO:0008216)
1.0	10.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
1.0	3.1	GO:0072666	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
1.0	4.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.0	4.1	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
1.0	4.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.0	8.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
1.0	7.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
1.0	4.0	GO:0033047	metaphase/anaphase transition of mitotic cell cycle(GO:0007091) regulation of mitotic sister chromatid separation(GO:0010965) regulation of mitotic sister chromatid segregation(GO:0033047) metaphase/anaphase transition of cell cycle(GO:0044784) mitotic sister chromatid separation(GO:0051306)
1.0	1.0	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
1.0	2.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.0	14.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
1.0	8.0	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
1.0	5.0	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
1.0	6.0	GO:0045730	respiratory burst(GO:0045730)
1.0	5.0	GO:0007096	regulation of exit from mitosis(GO:0007096)
1.0	1.0	GO:0033261	obsolete regulation of S phase(GO:0033261)
1.0	1.0	GO:0071459	protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
1.0	5.0	GO:0060017	parathyroid gland development(GO:0060017)
1.0	7.0	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
1.0	1.0	GO:0050688	regulation of defense response to virus(GO:0050688)
1.0	4.0	GO:0008045	motor neuron axon guidance(GO:0008045)
1.0	1.0	GO:0080111	DNA demethylation(GO:0080111)
1.0	2.0	GO:0006154	adenosine catabolic process(GO:0006154)
1.0	3.0	GO:0051593	response to folic acid(GO:0051593)
1.0	6.9	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
1.0	8.9	GO:0007032	endosome organization(GO:0007032)
1.0	2.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
1.0	5.9	GO:0051597	response to methylmercury(GO:0051597)
1.0	8.8	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
1.0	19.5	GO:0016579	protein deubiquitination(GO:0016579)
1.0	1.0	GO:0010824	regulation of centrosome duplication(GO:0010824) regulation of centrosome cycle(GO:0046605)
1.0	1.9	GO:0001714	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
1.0	18.5	GO:0007051	spindle organization(GO:0007051)
1.0	6.8	GO:0015813	L-glutamate transport(GO:0015813)
1.0	2.9	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
1.0	1.9	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
1.0	1.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.0	3.8	GO:0051452	intracellular pH reduction(GO:0051452)
1.0	90.1	GO:0016071	mRNA metabolic process(GO:0016071)
1.0	1.9	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
1.0	1.0	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
1.0	1.9	GO:0007412	axon target recognition(GO:0007412)
1.0	1.0	GO:0002507	tolerance induction(GO:0002507)
1.0	1.9	GO:0009405	pathogenesis(GO:0009405)
1.0	2.9	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.0	1.9	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.9	1.9	GO:0009156	ribonucleoside monophosphate biosynthetic process(GO:0009156)
0.9	1.9	GO:0060155	platelet dense granule organization(GO:0060155)
0.9	0.9	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.9	2.8	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.9	4.7	GO:0051928	positive regulation of calcium ion transport(GO:0051928)
0.9	4.7	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.9	0.9	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.9	4.7	GO:0032873	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.9	5.6	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.9	67.7	GO:0022904	respiratory electron transport chain(GO:0022904)
0.9	2.8	GO:0045056	transcytosis(GO:0045056)
0.9	2.8	GO:0051828	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.9	3.7	GO:0006572	tyrosine catabolic process(GO:0006572)
0.9	0.9	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.9	0.9	GO:0002328	pro-B cell differentiation(GO:0002328)
0.9	14.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.9	90.6	GO:0019941	modification-dependent protein catabolic process(GO:0019941) modification-dependent macromolecule catabolic process(GO:0043632)
0.9	0.9	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.9	1.8	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.9	12.9	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.9	62.6	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.9	3.7	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.9	90.0	GO:0006184	obsolete GTP catabolic process(GO:0006184)
0.9	4.6	GO:0070189	kynurenine metabolic process(GO:0070189)
0.9	13.8	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.9	29.3	GO:0009185	ribonucleoside diphosphate metabolic process(GO:0009185) ADP metabolic process(GO:0046031)
0.9	0.9	GO:0003181	heart valve development(GO:0003170) atrioventricular valve development(GO:0003171) heart valve morphogenesis(GO:0003179) atrioventricular valve morphogenesis(GO:0003181)
0.9	18.2	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.9	2.7	GO:0045123	cellular extravasation(GO:0045123)
0.9	2.7	GO:0006020	inositol metabolic process(GO:0006020)
0.9	0.9	GO:0006997	nucleus organization(GO:0006997)
0.9	11.8	GO:0000080	mitotic G1 phase(GO:0000080)
0.9	5.4	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.9	2.7	GO:0006855	drug transmembrane transport(GO:0006855)
0.9	0.9	GO:1901264	carbohydrate derivative transport(GO:1901264)
0.9	4.5	GO:0035095	behavioral response to nicotine(GO:0035095)
0.9	5.4	GO:0009303	rRNA transcription(GO:0009303)
0.9	1.8	GO:0031929	TOR signaling(GO:0031929)
0.9	0.9	GO:0035608	protein deglutamylation(GO:0035608)
0.9	3.6	GO:0006479	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.9	2.7	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.9	1.8	GO:0045655	regulation of monocyte differentiation(GO:0045655)
0.9	0.9	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.9	7.1	GO:0015992	proton transport(GO:0015992)
0.9	0.9	GO:2001259	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.9	1.8	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.9	1.8	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.9	1.8	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.9	9.6	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.9	1.7	GO:0009106	lipoate metabolic process(GO:0009106)
0.9	0.9	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.9	41.6	GO:0006826	iron ion transport(GO:0006826)
0.9	4.3	GO:0015074	DNA integration(GO:0015074)
0.9	2.6	GO:0015917	aminophospholipid transport(GO:0015917)
0.9	1.7	GO:0051788	response to misfolded protein(GO:0051788)
0.9	1.7	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.9	1.7	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.9	0.9	GO:0006490	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.8	0.8	GO:0055070	copper ion homeostasis(GO:0055070)
0.8	2.5	GO:1902806	regulation of cell cycle G1/S phase transition(GO:1902806) regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.8	4.2	GO:0046689	response to mercury ion(GO:0046689)
0.8	2.5	GO:0007028	cytoplasm organization(GO:0007028)
0.8	5.0	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.8	5.8	GO:0050957	equilibrioception(GO:0050957)
0.8	1.7	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.8	0.8	GO:0014805	smooth muscle adaptation(GO:0014805)
0.8	6.6	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.8	2.5	GO:0051298	centrosome duplication(GO:0051298)
0.8	0.8	GO:0048002	antigen processing and presentation of peptide antigen(GO:0048002)
0.8	19.8	GO:0000236	mitotic prometaphase(GO:0000236)
0.8	5.0	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.8	21.4	GO:0006458	'de novo' protein folding(GO:0006458)
0.8	4.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.8	4.1	GO:0006004	fucose metabolic process(GO:0006004)
0.8	2.5	GO:0001570	vasculogenesis(GO:0001570)
0.8	1.6	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.8	15.5	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.8	3.3	GO:1902603	carnitine shuttle(GO:0006853) intracellular lipid transport(GO:0032365) carnitine transmembrane transport(GO:1902603)
0.8	43.8	GO:0008033	tRNA processing(GO:0008033)
0.8	3.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.8	7.3	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.8	32.3	GO:0006364	rRNA processing(GO:0006364)
0.8	2.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.8	3.2	GO:0000154	rRNA modification(GO:0000154)
0.8	0.8	GO:0002720	positive regulation of cytokine production involved in immune response(GO:0002720)
0.8	64.4	GO:0006325	chromatin organization(GO:0006325)
0.8	54.4	GO:0006415	translational termination(GO:0006415)
0.8	66.2	GO:0006457	protein folding(GO:0006457)
0.8	19.1	GO:0006695	cholesterol biosynthetic process(GO:0006695)
0.8	8.8	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.8	3.2	GO:0000050	urea cycle(GO:0000050)
0.8	3.2	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.8	1.6	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.8	5.6	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8	13.5	GO:0005980	glycogen catabolic process(GO:0005980)
0.8	2.4	GO:0032309	icosanoid secretion(GO:0032309)
0.8	0.8	GO:0050832	defense response to fungus(GO:0050832)
0.8	0.8	GO:0051503	adenine nucleotide transport(GO:0051503)
0.8	17.2	GO:0006914	autophagy(GO:0006914)
0.8	3.9	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.8	3.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.8	4.7	GO:0006839	mitochondrial transport(GO:0006839)
0.8	1.6	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.8	120.2	GO:0044419	interspecies interaction between organisms(GO:0044419)
0.8	1.6	GO:0032459	regulation of protein oligomerization(GO:0032459)
0.8	5.5	GO:0009067	aspartate family amino acid biosynthetic process(GO:0009067)
0.8	0.8	GO:0010002	cardioblast differentiation(GO:0010002)
0.8	3.8	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.8	15.3	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.8	3.8	GO:0000087	mitotic M phase(GO:0000087)
0.8	27.2	GO:0006396	RNA processing(GO:0006396)
0.8	7.6	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.8	0.8	GO:0018208	peptidyl-proline modification(GO:0018208)
0.8	0.8	GO:0001840	neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.8	0.8	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.8	6.8	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.8	7.5	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.7	0.7	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.7	123.5	GO:0006412	translation(GO:0006412)
0.7	7.5	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.7	0.7	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.7	3.0	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.7	5.9	GO:0030500	regulation of bone mineralization(GO:0030500)
0.7	1.5	GO:0001782	B cell homeostasis(GO:0001782)
0.7	3.0	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.7	11.1	GO:0051169	nuclear transport(GO:0051169)
0.7	1.5	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response(GO:0002294) T-helper cell differentiation(GO:0042093)
0.7	0.7	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.7	0.7	GO:0046185	aldehyde catabolic process(GO:0046185)
0.7	1.5	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.7	1.5	GO:0033363	secretory granule organization(GO:0033363)
0.7	3.6	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7	32.7	GO:0016567	protein ubiquitination(GO:0016567)
0.7	2.9	GO:0000012	single strand break repair(GO:0000012)
0.7	1.5	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.7	0.7	GO:0046634	regulation of alpha-beta T cell activation(GO:0046634)
0.7	2.2	GO:0021754	facial nucleus development(GO:0021754)
0.7	10.1	GO:1901607	alpha-amino acid biosynthetic process(GO:1901607)
0.7	2.9	GO:0002418	immune response to tumor cell(GO:0002418)
0.7	0.7	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.7	7.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.7	3.6	GO:0006903	vesicle targeting(GO:0006903)
0.7	67.3	GO:0006281	DNA repair(GO:0006281)
0.7	1.4	GO:0048311	mitochondrion distribution(GO:0048311)
0.7	7.9	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.7	1.4	GO:0021702	cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.7	1.4	GO:0055078	sodium ion homeostasis(GO:0055078)
0.7	1.4	GO:0033483	oxygen homeostasis(GO:0032364) gas homeostasis(GO:0033483)
0.7	38.3	GO:0097190	apoptotic signaling pathway(GO:0097190)
0.7	0.7	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.7	7.1	GO:0007219	Notch signaling pathway(GO:0007219)
0.7	7.8	GO:0030097	hemopoiesis(GO:0030097)
0.7	4.2	GO:0006465	signal peptide processing(GO:0006465)
0.7	2.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.7	0.7	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.7	4.9	GO:0015693	magnesium ion transport(GO:0015693)
0.7	1.4	GO:0061371	heart looping(GO:0001947) embryonic heart tube morphogenesis(GO:0003143) determination of heart left/right asymmetry(GO:0061371)
0.7	1.4	GO:0018200	peptidyl-glutamic acid modification(GO:0018200)
0.7	1.4	GO:0006721	terpenoid metabolic process(GO:0006721)
0.7	0.7	GO:0071277	cellular response to calcium ion(GO:0071277)
0.7	2.8	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.7	4.1	GO:0044065	regulation of respiratory gaseous exchange by neurological system process(GO:0002087) regulation of respiratory system process(GO:0044065)
0.7	2.7	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.7	1.4	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.7	4.1	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.7	1.4	GO:0046174	polyol catabolic process(GO:0046174)
0.7	6.8	GO:0030101	natural killer cell activation(GO:0030101)
0.7	1.4	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.7	1.4	GO:0015793	glycerol transport(GO:0015793)
0.7	1.3	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.7	4.0	GO:0007041	lysosomal transport(GO:0007041)
0.7	2.0	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.7	2.7	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.7	1.3	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.7	2.0	GO:0048505	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.7	2.0	GO:0032446	protein modification by small protein conjugation(GO:0032446)
0.7	1.3	GO:0014823	response to activity(GO:0014823)
0.7	2.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.7	1.3	GO:0034030	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.7	1.3	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.7	1.3	GO:0006862	nucleotide transport(GO:0006862)
0.7	4.6	GO:0010467	gene expression(GO:0010467)
0.7	2.6	GO:0016601	Rac protein signal transduction(GO:0016601)
0.6	1.9	GO:1903556	negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556)
0.6	2.6	GO:0006101	citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.6	1.3	GO:0046950	cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952)
0.6	5.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.6	0.6	GO:0032200	telomere organization(GO:0032200)
0.6	3.2	GO:0015914	phospholipid transport(GO:0015914)
0.6	24.3	GO:0009199	ribonucleoside triphosphate metabolic process(GO:0009199) purine ribonucleoside triphosphate metabolic process(GO:0009205)
0.6	32.5	GO:0038179	neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.6	23.5	GO:0006486	protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.6	2.5	GO:0046823	negative regulation of nucleocytoplasmic transport(GO:0046823)
0.6	0.6	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.6	1.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.6	6.3	GO:0000187	activation of MAPK activity(GO:0000187)
0.6	26.2	GO:0008654	phospholipid biosynthetic process(GO:0008654)
0.6	0.6	GO:0016048	detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.6	12.4	GO:0007286	spermatid development(GO:0007286)
0.6	0.6	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.6	1.2	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.6	1.9	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.6	3.1	GO:0043094	cellular metabolic compound salvage(GO:0043094)
0.6	1.2	GO:0007080	mitotic metaphase plate congression(GO:0007080) metaphase plate congression(GO:0051310)
0.6	3.7	GO:0002920	regulation of humoral immune response(GO:0002920)
0.6	0.6	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.6	5.5	GO:0003009	skeletal muscle contraction(GO:0003009)
0.6	15.3	GO:0007602	phototransduction(GO:0007602)
0.6	1.2	GO:0019320	hexose catabolic process(GO:0019320)
0.6	2.4	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.6	1.8	GO:0007059	chromosome segregation(GO:0007059)
0.6	1.8	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6	3.6	GO:0009953	dorsal/ventral pattern formation(GO:0009953)
0.6	8.4	GO:0009615	response to virus(GO:0009615)
0.6	1.8	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.6	0.6	GO:0001302	replicative cell aging(GO:0001302)
0.6	6.0	GO:0044843	G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843)
0.6	1.8	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.6	1.2	GO:0018065	protein-cofactor linkage(GO:0018065)
0.6	3.0	GO:0045214	sarcomere organization(GO:0045214)
0.6	0.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.6	8.3	GO:0005977	glycogen metabolic process(GO:0005977)
0.6	1.8	GO:0030157	pancreatic juice secretion(GO:0030157)
0.6	0.6	GO:0032455	nerve growth factor processing(GO:0032455)
0.6	0.6	GO:0007258	JUN phosphorylation(GO:0007258)
0.6	0.6	GO:0048799	ossification involved in bone maturation(GO:0043931) organ maturation(GO:0048799) bone maturation(GO:0070977)
0.6	1.2	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.6	2.9	GO:0052646	alditol phosphate metabolic process(GO:0052646)
0.6	2.9	GO:0045762	positive regulation of adenylate cyclase activity(GO:0045762)
0.6	2.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.6	1.2	GO:0003416	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.6	5.8	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.6	0.6	GO:0048566	embryonic digestive tract development(GO:0048566)
0.6	2.3	GO:0070206	protein trimerization(GO:0070206)
0.6	0.6	GO:0034130	toll-like receptor 1 signaling pathway(GO:0034130) toll-like receptor 2 signaling pathway(GO:0034134)
0.6	4.6	GO:0006200	obsolete ATP catabolic process(GO:0006200)
0.6	1.7	GO:0007031	peroxisome organization(GO:0007031)
0.6	1.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.6	0.6	GO:0032808	lacrimal gland development(GO:0032808)
0.6	2.8	GO:0006546	glycine catabolic process(GO:0006546)
0.6	7.3	GO:0006026	aminoglycan catabolic process(GO:0006026)
0.6	2.2	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.6	1.7	GO:0015886	heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.6	1.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.6	11.1	GO:0007005	mitochondrion organization(GO:0007005)
0.6	1.1	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.6	10.5	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.5	1.1	GO:0071326	cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.5	1.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.5	16.7	GO:0006968	cellular defense response(GO:0006968)
0.5	2.7	GO:1901661	quinone metabolic process(GO:1901661)
0.5	1.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.5	1.6	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.5	0.5	GO:0016064	immunoglobulin mediated immune response(GO:0016064) B cell mediated immunity(GO:0019724)
0.5	0.5	GO:0097205	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.5	1.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.5	2.1	GO:0035329	hippo signaling(GO:0035329)
0.5	6.8	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.5	1.6	GO:0043249	erythrocyte maturation(GO:0043249)
0.5	11.4	GO:0034340	response to type I interferon(GO:0034340)
0.5	0.5	GO:0031641	regulation of myelination(GO:0031641)
0.5	2.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.5	2.1	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.5	1.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.5	0.5	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
0.5	1.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.5	6.0	GO:0043401	steroid hormone mediated signaling pathway(GO:0043401)
0.5	2.5	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.5	0.5	GO:0032846	positive regulation of homeostatic process(GO:0032846)
0.5	2.0	GO:0030225	macrophage differentiation(GO:0030225)
0.5	0.5	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.5	0.5	GO:0045112	integrin biosynthetic process(GO:0045112)
0.5	1.0	GO:0006577	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.5	3.4	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.5	0.5	GO:0034660	ncRNA metabolic process(GO:0034660)
0.5	3.4	GO:0007030	Golgi organization(GO:0007030)
0.5	1.5	GO:0030261	chromosome condensation(GO:0030261)
0.5	4.4	GO:0048880	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.5	2.9	GO:0045930	negative regulation of mitotic cell cycle(GO:0045930)
0.5	3.4	GO:0015931	nucleobase-containing compound transport(GO:0015931)
0.5	1.4	GO:0010039	response to iron ion(GO:0010039)
0.5	1.0	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.5	1.0	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.5	0.5	GO:0009880	embryonic pattern specification(GO:0009880)
0.5	1.9	GO:0010107	potassium ion import(GO:0010107)
0.5	1.4	GO:0043488	regulation of mRNA stability(GO:0043488)
0.5	5.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.5	0.5	GO:0001936	regulation of endothelial cell proliferation(GO:0001936)
0.5	12.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.5	0.9	GO:0015705	iodide transport(GO:0015705)
0.5	0.5	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.5	28.2	GO:0007067	mitotic nuclear division(GO:0007067)
0.5	0.9	GO:0006772	thiamine metabolic process(GO:0006772)
0.5	5.5	GO:0030099	myeloid cell differentiation(GO:0030099)
0.5	0.9	GO:0010212	response to ionizing radiation(GO:0010212)
0.5	1.4	GO:0090208	positive regulation of triglyceride metabolic process(GO:0090208)
0.5	0.5	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.5	0.9	GO:0071318	cellular response to ATP(GO:0071318)
0.5	1.4	GO:0042447	hormone catabolic process(GO:0042447)
0.4	1.8	GO:0006776	vitamin A metabolic process(GO:0006776)
0.4	2.7	GO:0031647	regulation of protein stability(GO:0031647)
0.4	5.7	GO:0048278	vesicle docking(GO:0048278)
0.4	1.8	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.4	1.3	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.4	1.7	GO:0002682	regulation of immune system process(GO:0002682)
0.4	4.4	GO:0035036	sperm-egg recognition(GO:0035036)
0.4	3.0	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.4	3.0	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.4	0.4	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.4	2.1	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.4	5.1	GO:0019835	cytolysis(GO:0019835)
0.4	1.7	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4	0.4	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.4	0.8	GO:0006907	pinocytosis(GO:0006907)
0.4	5.4	GO:0042254	ribosome biogenesis(GO:0042254)
0.4	0.8	GO:0046655	folic acid metabolic process(GO:0046655)
0.4	0.8	GO:0001510	RNA methylation(GO:0001510)
0.4	0.8	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.4	0.8	GO:0009415	response to water(GO:0009415)
0.4	0.4	GO:0033692	cellular polysaccharide biosynthetic process(GO:0033692)
0.4	0.4	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.4	3.6	GO:0071593	T cell activation(GO:0042110) leukocyte aggregation(GO:0070486) T cell aggregation(GO:0070489) lymphocyte aggregation(GO:0071593)
0.4	3.2	GO:0002021	response to dietary excess(GO:0002021)
0.4	29.4	GO:0006470	protein dephosphorylation(GO:0006470)
0.4	0.4	GO:0035587	purinergic receptor signaling pathway(GO:0035587)
0.4	0.4	GO:0098543	detection of other organism(GO:0098543)
0.4	5.1	GO:0032011	ARF protein signal transduction(GO:0032011)
0.4	1.9	GO:0006354	DNA-templated transcription, elongation(GO:0006354)
0.4	1.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.4	0.4	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.4	0.4	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.4	1.1	GO:0042180	cellular ketone metabolic process(GO:0042180)
0.4	1.9	GO:0090630	activation of GTPase activity(GO:0090630)
0.4	3.7	GO:0008344	adult locomotory behavior(GO:0008344)
0.4	2.2	GO:0042572	retinol metabolic process(GO:0042572)
0.4	0.4	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.4	2.6	GO:0005513	detection of calcium ion(GO:0005513)
0.4	36.6	GO:0006897	endocytosis(GO:0006897)
0.4	4.0	GO:0006986	response to unfolded protein(GO:0006986)
0.4	1.5	GO:0006974	cellular response to DNA damage stimulus(GO:0006974)
0.4	1.8	GO:0006702	androgen biosynthetic process(GO:0006702)
0.4	0.4	GO:0003016	respiratory system process(GO:0003016)
0.4	1.1	GO:0007128	meiotic prophase I(GO:0007128)
0.4	1.8	GO:0032259	methylation(GO:0032259)
0.4	4.7	GO:0008272	sulfate transport(GO:0008272)
0.4	0.4	GO:0032096	negative regulation of response to food(GO:0032096)
0.4	1.4	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.4	65.4	GO:0007264	small GTPase mediated signal transduction(GO:0007264)
0.4	1.1	GO:0009062	fatty acid catabolic process(GO:0009062)
0.3	0.7	GO:0006505	GPI anchor metabolic process(GO:0006505)
0.3	0.3	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.3	0.7	GO:0048706	embryonic skeletal system development(GO:0048706)
0.3	0.7	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.3	1.0	GO:0019674	NAD metabolic process(GO:0019674)
0.3	0.7	GO:0048535	lymph node development(GO:0048535)
0.3	1.7	GO:0045088	regulation of innate immune response(GO:0045088)
0.3	0.3	GO:0046330	positive regulation of JNK cascade(GO:0046330)
0.3	4.7	GO:0001906	cell killing(GO:0001906)
0.3	2.4	GO:0009755	hormone-mediated signaling pathway(GO:0009755)
0.3	1.0	GO:0008343	adult feeding behavior(GO:0008343)
0.3	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.3	3.3	GO:0007632	visual behavior(GO:0007632)
0.3	0.7	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3	0.3	GO:0051006	positive regulation of lipoprotein lipase activity(GO:0051006) positive regulation of triglyceride lipase activity(GO:0061365)
0.3	0.3	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.3	2.6	GO:0042246	tissue regeneration(GO:0042246)
0.3	1.0	GO:0031018	endocrine pancreas development(GO:0031018)
0.3	1.0	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.3	9.8	GO:0045087	innate immune response(GO:0045087)
0.3	0.3	GO:0016126	sterol biosynthetic process(GO:0016126)
0.3	1.3	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.3	0.6	GO:0016125	sterol metabolic process(GO:0016125)
0.3	0.3	GO:0002200	somatic diversification of immune receptors(GO:0002200)
0.3	27.7	GO:0043087	regulation of GTPase activity(GO:0043087)
0.3	0.6	GO:0010629	negative regulation of gene expression(GO:0010629)
0.3	1.9	GO:0032526	response to retinoic acid(GO:0032526)
0.3	1.0	GO:0048863	stem cell differentiation(GO:0048863)
0.3	0.6	GO:0060259	regulation of feeding behavior(GO:0060259)
0.3	0.9	GO:0045823	positive regulation of heart contraction(GO:0045823)
0.3	0.3	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.3	1.9	GO:0042438	melanin biosynthetic process(GO:0042438)
0.3	0.6	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.3	10.6	GO:0006959	humoral immune response(GO:0006959)
0.3	0.6	GO:0031331	positive regulation of cellular catabolic process(GO:0031331)
0.3	3.9	GO:0007179	transforming growth factor beta receptor signaling pathway(GO:0007179)
0.3	0.9	GO:0071496	cellular response to external stimulus(GO:0071496)
0.3	11.9	GO:0198738	Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.3	4.1	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.3	0.6	GO:0009895	negative regulation of catabolic process(GO:0009895)
0.3	1.2	GO:0031100	organ regeneration(GO:0031100)
0.3	2.6	GO:0051289	protein homotetramerization(GO:0051289)
0.3	0.3	GO:0040009	regulation of growth rate(GO:0040009)
0.3	0.3	GO:0006825	copper ion transport(GO:0006825)
0.3	1.1	GO:0051341	regulation of oxidoreductase activity(GO:0051341)
0.3	5.1	GO:0006665	sphingolipid metabolic process(GO:0006665)
0.3	0.8	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.3	4.5	GO:0030308	negative regulation of cell growth(GO:0030308)
0.3	39.2	GO:0015031	protein transport(GO:0015031)
0.3	0.3	GO:0001880	Mullerian duct regression(GO:0001880)
0.3	0.3	GO:0046325	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.3	1.1	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.3	1.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.3	0.3	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.3	1.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.3	0.3	GO:0043255	regulation of carbohydrate biosynthetic process(GO:0043255)
0.3	1.3	GO:0006310	DNA recombination(GO:0006310)
0.3	0.5	GO:0006473	protein acetylation(GO:0006473)
0.3	0.3	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.3	1.8	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.3	0.8	GO:0034762	regulation of transmembrane transport(GO:0034762)
0.3	1.5	GO:0006401	RNA catabolic process(GO:0006401)
0.3	0.3	GO:0051262	protein tetramerization(GO:0051262)
0.3	0.3	GO:0043406	positive regulation of MAP kinase activity(GO:0043406)
0.3	0.3	GO:0033014	tetrapyrrole biosynthetic process(GO:0033014)
0.3	5.3	GO:0016197	endosomal transport(GO:0016197)
0.2	1.0	GO:0006706	steroid catabolic process(GO:0006706)
0.2	1.7	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.2	34.8	GO:0016192	vesicle-mediated transport(GO:0016192)
0.2	0.2	GO:0046877	regulation of saliva secretion(GO:0046877)
0.2	0.2	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.2	0.2	GO:1905145	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) cellular response to ammonium ion(GO:0071242) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2	0.5	GO:0032506	mitotic cytokinesis(GO:0000281) cytokinetic process(GO:0032506)
0.2	0.5	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2	0.2	GO:0002544	chronic inflammatory response(GO:0002544)
0.2	0.5	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.2	28.9	GO:0006955	immune response(GO:0006955)
0.2	0.5	GO:0032368	regulation of lipid transport(GO:0032368)
0.2	2.5	GO:0015701	bicarbonate transport(GO:0015701)
0.2	0.7	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.2	2.5	GO:0071554	cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.2	0.4	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.2	38.1	GO:0007049	cell cycle(GO:0007049)
0.2	0.9	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.2	0.4	GO:0010883	regulation of lipid storage(GO:0010883)
0.2	0.2	GO:0010455	positive regulation of cell fate commitment(GO:0010455)
0.2	3.0	GO:0022900	electron transport chain(GO:0022900)
0.2	0.2	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.2	0.4	GO:0060711	labyrinthine layer development(GO:0060711)
0.2	5.3	GO:0030048	actin filament-based movement(GO:0030048)
0.2	0.2	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178)
0.2	0.6	GO:0042593	carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.2	0.4	GO:0007398	ectoderm development(GO:0007398)
0.2	0.6	GO:0010595	positive regulation of endothelial cell migration(GO:0010595)
0.2	1.9	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2	0.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.2	2.2	GO:0043687	post-translational protein modification(GO:0043687)
0.2	10.5	GO:0006869	lipid transport(GO:0006869)
0.2	0.6	GO:0010043	response to zinc ion(GO:0010043)
0.2	204.1	GO:0016070	RNA metabolic process(GO:0016070)
0.2	0.4	GO:0007569	cell aging(GO:0007569)
0.2	0.5	GO:0007340	acrosome reaction(GO:0007340)
0.2	0.5	GO:0021766	hippocampus development(GO:0021766)
0.2	0.2	GO:0015840	urea transport(GO:0015840)
0.2	0.7	GO:0006091	generation of precursor metabolites and energy(GO:0006091)
0.2	31.2	GO:0006915	apoptotic process(GO:0006915)
0.2	0.2	GO:0032880	regulation of protein localization(GO:0032880)
0.2	0.3	GO:0007635	chemosensory behavior(GO:0007635)
0.2	0.2	GO:0048534	hematopoietic or lymphoid organ development(GO:0048534)
0.2	0.9	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.2	0.3	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.2	1.5	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.2	0.3	GO:0035050	embryonic heart tube development(GO:0035050)
0.2	3.8	GO:0050900	leukocyte migration(GO:0050900)
0.1	0.1	GO:0030856	regulation of epithelial cell differentiation(GO:0030856)
0.1	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	1.6	GO:0010038	response to metal ion(GO:0010038)
0.1	0.1	GO:0001658	branching involved in ureteric bud morphogenesis(GO:0001658)
0.1	0.4	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.1	0.1	GO:0044257	cellular protein catabolic process(GO:0044257)
0.1	39.7	GO:0006508	proteolysis(GO:0006508)
0.1	0.5	GO:0040014	regulation of multicellular organism growth(GO:0040014)
0.1	2.2	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.1	3.1	GO:0050909	sensory perception of taste(GO:0050909)
0.1	0.4	GO:0006691	leukotriene metabolic process(GO:0006691)
0.1	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.1	0.5	GO:0009072	aromatic amino acid family metabolic process(GO:0009072)
0.1	0.1	GO:0048484	enteric nervous system development(GO:0048484)
0.1	0.1	GO:0030826	cGMP-mediated signaling(GO:0019934) regulation of cGMP biosynthetic process(GO:0030826)
0.1	0.3	GO:0007498	mesoderm development(GO:0007498)
0.1	0.1	GO:0009251	glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1	0.4	GO:0060041	retina development in camera-type eye(GO:0060041)
0.1	1.4	GO:0060271	cilium morphogenesis(GO:0060271)
0.1	0.1	GO:0032094	response to food(GO:0032094)
0.1	0.1	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.1	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	17.3	GO:0055114	oxidation-reduction process(GO:0055114)
0.1	0.1	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1	0.2	GO:0019321	pentose metabolic process(GO:0019321)
0.1	0.2	GO:0030277	epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.2	GO:0042446	hormone biosynthetic process(GO:0042446)
0.1	0.3	GO:0030278	regulation of ossification(GO:0030278)
0.1	0.1	GO:0043297	apical junction assembly(GO:0043297)
0.1	0.4	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.1	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.1	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.3	GO:0042552	myelination(GO:0042552)
0.0	0.0	GO:0072330	monocarboxylic acid biosynthetic process(GO:0072330)
0.0	0.0	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.6	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.3	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.3	GO:0009063	cellular amino acid catabolic process(GO:0009063)
0.0	0.0	GO:0051276	chromosome organization(GO:0051276)
0.0	0.5	GO:0043269	regulation of ion transport(GO:0043269)
0.0	0.1	GO:0019236	response to pheromone(GO:0019236)
0.0	0.0	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.7	GO:0009410	response to xenobiotic stimulus(GO:0009410)
0.0	0.0	GO:0072009	renal tubule development(GO:0061326) nephron epithelium development(GO:0072009) nephron tubule development(GO:0072080)
0.0	0.0	GO:0018205	peptidyl-lysine modification(GO:0018205)
0.0	0.1	GO:0050892	intestinal absorption(GO:0050892)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.4	GO:0046907	intracellular transport(GO:0046907)
0.0	0.1	GO:0009855	determination of bilateral symmetry(GO:0009855)
0.0	0.0	GO:0007260	tyrosine phosphorylation of STAT protein(GO:0007260)
0.0	6.3	GO:0007608	sensory perception of smell(GO:0007608)
0.0	0.0	GO:0060052	intermediate filament bundle assembly(GO:0045110) neurofilament cytoskeleton organization(GO:0060052)
0.0	0.0	GO:0045471	response to ethanol(GO:0045471)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.3	16.0	GO:0072487	MSL complex(GO:0072487)
5.2	20.8	GO:0070820	tertiary granule(GO:0070820)
5.2	20.7	GO:0005826	actomyosin contractile ring(GO:0005826)
4.7	18.9	GO:0005827	polar microtubule(GO:0005827)
4.2	25.1	GO:0071778	obsolete WINAC complex(GO:0071778)
4.1	12.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
3.6	14.5	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
3.5	10.4	GO:0000124	SAGA complex(GO:0000124)
3.4	10.2	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
3.2	9.5	GO:0005945	6-phosphofructokinase complex(GO:0005945)
3.2	9.5	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
3.1	3.1	GO:0070938	contractile ring(GO:0070938)
3.0	11.9	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
3.0	11.9	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.9	26.4	GO:0042555	MCM complex(GO:0042555)
2.9	11.5	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
2.8	22.6	GO:0048786	presynaptic active zone(GO:0048786)
2.7	13.7	GO:0005797	Golgi medial cisterna(GO:0005797)
2.7	8.1	GO:0032444	activin responsive factor complex(GO:0032444)
2.6	31.8	GO:0010494	cytoplasmic stress granule(GO:0010494)
2.6	7.8	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
2.6	13.0	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
2.6	15.5	GO:0042382	paraspeckles(GO:0042382)
2.6	43.5	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
2.5	10.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
2.4	29.1	GO:0001772	immunological synapse(GO:0001772)
2.3	9.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
2.3	6.9	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.3	13.8	GO:0031264	death-inducing signaling complex(GO:0031264)
2.3	6.8	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
2.3	18.1	GO:0071564	npBAF complex(GO:0071564)
2.3	6.8	GO:0032009	early phagosome(GO:0032009)
2.2	15.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
2.2	4.4	GO:0032593	insulin-responsive compartment(GO:0032593)
2.2	17.7	GO:0031095	platelet dense tubular network membrane(GO:0031095)
2.2	30.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
2.2	4.3	GO:0044462	external encapsulating structure part(GO:0044462)
2.2	43.1	GO:0031519	PcG protein complex(GO:0031519)
2.1	4.2	GO:0042575	DNA polymerase complex(GO:0042575)
2.1	2.1	GO:0042613	MHC class II protein complex(GO:0042613)
2.1	12.7	GO:0070688	MLL5-L complex(GO:0070688)
2.1	4.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
2.1	2.1	GO:0031090	organelle membrane(GO:0031090)
2.1	8.3	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
2.1	4.1	GO:0031932	TORC2 complex(GO:0031932)
2.0	10.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
2.0	12.1	GO:0051233	spindle midzone(GO:0051233)
2.0	12.0	GO:0005626	obsolete insoluble fraction(GO:0005626)
2.0	16.0	GO:0000109	nucleotide-excision repair complex(GO:0000109)
2.0	14.0	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
2.0	5.9	GO:0042405	nuclear inclusion body(GO:0042405)
2.0	7.9	GO:0016602	CCAAT-binding factor complex(GO:0016602)
1.9	9.6	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
1.9	5.6	GO:0000138	Golgi trans cisterna(GO:0000138)
1.9	5.6	GO:0008537	proteasome activator complex(GO:0008537)
1.9	13.0	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
1.8	5.5	GO:0030891	VCB complex(GO:0030891)
1.8	16.3	GO:0043020	NADPH oxidase complex(GO:0043020)
1.8	1.8	GO:0030686	90S preribosome(GO:0030686)
1.8	7.2	GO:0016589	NURF complex(GO:0016589)
1.8	1.8	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
1.8	41.2	GO:0097610	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
1.8	66.0	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
1.8	17.8	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
1.8	5.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.8	8.8	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
1.7	8.7	GO:0016514	SWI/SNF complex(GO:0016514)
1.7	3.5	GO:0015935	small ribosomal subunit(GO:0015935)
1.7	1.7	GO:0070852	cell body fiber(GO:0070852)
1.7	3.4	GO:0031010	ISWI-type complex(GO:0031010)
1.7	11.9	GO:0048188	Set1C/COMPASS complex(GO:0048188)
1.7	112.5	GO:0005643	nuclear pore(GO:0005643)
1.7	15.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
1.7	1.7	GO:0045178	basal part of cell(GO:0045178)
1.7	15.1	GO:0042101	T cell receptor complex(GO:0042101)
1.7	8.4	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.7	3.3	GO:0038201	TOR complex(GO:0038201)
1.7	6.6	GO:0005638	lamin filament(GO:0005638)
1.6	34.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.6	4.9	GO:0005828	kinetochore microtubule(GO:0005828)
1.6	8.1	GO:0070695	FHF complex(GO:0070695)
1.6	161.1	GO:0005741	mitochondrial outer membrane(GO:0005741)
1.6	87.8	GO:0016605	PML body(GO:0016605)
1.6	29.1	GO:0031201	SNARE complex(GO:0031201)
1.6	4.8	GO:0032059	bleb(GO:0032059)
1.6	4.8	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.6	19.0	GO:0032039	integrator complex(GO:0032039)
1.6	4.7	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.6	4.7	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.6	26.9	GO:0032420	stereocilium(GO:0032420)
1.6	7.8	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
1.6	7.8	GO:0042824	MHC class I peptide loading complex(GO:0042824)
1.6	7.8	GO:0030121	AP-1 adaptor complex(GO:0030121)
1.6	23.4	GO:0030137	COPI-coated vesicle(GO:0030137)
1.6	14.0	GO:0032839	dendrite cytoplasm(GO:0032839)
1.6	9.3	GO:0005682	U5 snRNP(GO:0005682)
1.6	1.6	GO:0042641	actomyosin(GO:0042641)
1.5	7.7	GO:0000792	heterochromatin(GO:0000792)
1.5	7.7	GO:0005677	chromatin silencing complex(GO:0005677)
1.5	13.8	GO:0022624	proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
1.5	12.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
1.5	18.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.5	4.5	GO:0005884	actin filament(GO:0005884)
1.5	4.5	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
1.5	11.9	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
1.5	45.6	GO:0016592	mediator complex(GO:0016592)
1.5	49.5	GO:0017053	transcriptional repressor complex(GO:0017053)
1.4	2.9	GO:0070552	BRISC complex(GO:0070552)
1.4	4.3	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
1.4	15.9	GO:0035631	CD40 receptor complex(GO:0035631)
1.4	1.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
1.4	8.4	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
1.4	2.8	GO:0005902	microvillus(GO:0005902)
1.4	12.5	GO:0000930	gamma-tubulin complex(GO:0000930)
1.4	8.3	GO:0008385	IkappaB kinase complex(GO:0008385)
1.4	9.7	GO:0008290	F-actin capping protein complex(GO:0008290)
1.4	5.5	GO:0031088	platelet dense granule membrane(GO:0031088)
1.4	5.5	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
1.4	17.8	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
1.4	6.8	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.4	4.1	GO:0005876	spindle microtubule(GO:0005876)
1.4	4.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
1.4	4.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.3	10.8	GO:0005868	cytoplasmic dynein complex(GO:0005868)
1.3	4.0	GO:0031904	endosome lumen(GO:0031904)
1.3	21.3	GO:0008023	transcription elongation factor complex(GO:0008023)
1.3	4.0	GO:0002080	acrosomal membrane(GO:0002080)
1.3	3.9	GO:0071817	MMXD complex(GO:0071817)
1.3	1.3	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
1.3	5.2	GO:0000791	euchromatin(GO:0000791)
1.3	5.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
1.3	104.1	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
1.3	62.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
1.3	59.8	GO:0000922	spindle pole(GO:0000922)
1.3	12.7	GO:0005844	polysome(GO:0005844)
1.3	15.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
1.3	11.4	GO:0008180	COP9 signalosome(GO:0008180)
1.3	16.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
1.2	36.2	GO:0042645	mitochondrial nucleoid(GO:0042645)
1.2	26.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.2	7.5	GO:0034464	BBSome(GO:0034464)
1.2	14.9	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.2	11.1	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
1.2	53.1	GO:0055037	recycling endosome(GO:0055037)
1.2	4.9	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.2	3.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
1.2	4.9	GO:0016600	flotillin complex(GO:0016600)
1.2	9.8	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.2	3.7	GO:0001652	granular component(GO:0001652)
1.2	25.4	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
1.2	56.7	GO:0000790	nuclear chromatin(GO:0000790)
1.2	6.0	GO:0000346	transcription export complex(GO:0000346)
1.2	16.8	GO:0000178	exosome (RNase complex)(GO:0000178)
1.2	20.3	GO:0005871	kinesin complex(GO:0005871)
1.2	4.8	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
1.2	118.5	GO:0016607	nuclear speck(GO:0016607)
1.2	2.4	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
1.2	10.6	GO:0034362	low-density lipoprotein particle(GO:0034362)
1.2	5.9	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.2	3.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
1.2	11.7	GO:0030914	STAGA complex(GO:0030914)
1.2	2.3	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.2	1.2	GO:0000800	lateral element(GO:0000800)
1.2	3.5	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
1.2	8.1	GO:0000145	exocyst(GO:0000145)
1.2	4.6	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.2	45.0	GO:0000502	proteasome complex(GO:0000502)
1.2	2.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
1.1	33.3	GO:0030496	midbody(GO:0030496)
1.1	6.8	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
1.1	3.4	GO:0033276	transcription factor TFTC complex(GO:0033276)
1.1	111.7	GO:0005769	early endosome(GO:0005769)
1.1	5.6	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
1.1	9.0	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.1	4.5	GO:0000407	pre-autophagosomal structure(GO:0000407)
1.1	6.7	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.1	2.2	GO:0030125	clathrin vesicle coat(GO:0030125)
1.1	5.6	GO:0000796	condensin complex(GO:0000796)
1.1	4.4	GO:0005869	dynactin complex(GO:0005869)
1.1	1.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
1.1	39.4	GO:0000776	kinetochore(GO:0000776)
1.1	6.6	GO:0030992	intraciliary transport particle B(GO:0030992)
1.1	5.4	GO:0042589	zymogen granule membrane(GO:0042589)
1.1	88.5	GO:0005681	spliceosomal complex(GO:0005681)
1.1	31.2	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.1	9.7	GO:0017119	Golgi transport complex(GO:0017119)
1.1	96.4	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.1	25.4	GO:0005680	anaphase-promoting complex(GO:0005680)
1.1	119.6	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.1	4.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
1.0	3.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
1.0	7.3	GO:0000123	histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
1.0	14.5	GO:0005637	nuclear inner membrane(GO:0005637)
1.0	5.2	GO:0005883	neurofilament(GO:0005883)
1.0	45.2	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
1.0	5.1	GO:0016461	unconventional myosin complex(GO:0016461)
1.0	110.8	GO:0000785	chromatin(GO:0000785)
1.0	51.2	GO:0000151	ubiquitin ligase complex(GO:0000151)
1.0	26.6	GO:0016363	nuclear matrix(GO:0016363)
1.0	31.6	GO:0005758	mitochondrial intermembrane space(GO:0005758)
1.0	457.5	GO:0005654	nucleoplasm(GO:0005654)
1.0	4.1	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.0	13.2	GO:0000118	histone deacetylase complex(GO:0000118)
1.0	5.0	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
1.0	22.1	GO:0005798	Golgi-associated vesicle(GO:0005798)
1.0	2.0	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
1.0	34.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
1.0	2.9	GO:0005899	insulin receptor complex(GO:0005899)
1.0	22.5	GO:0031902	late endosome membrane(GO:0031902)
1.0	4.9	GO:0005832	chaperonin-containing T-complex(GO:0005832)
1.0	1.9	GO:0070531	BRCA1-A complex(GO:0070531)
1.0	1.0	GO:0045298	tubulin complex(GO:0045298)
1.0	47.2	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.9	22.5	GO:0005802	trans-Golgi network(GO:0005802)
0.9	4.7	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.9	20.5	GO:0005819	spindle(GO:0005819)
0.9	14.0	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.9	7.4	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.9	2.8	GO:0042588	zymogen granule(GO:0042588)
0.9	2.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.9	8.3	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.9	53.4	GO:0031965	nuclear membrane(GO:0031965)
0.9	20.1	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.9	33.9	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.9	13.7	GO:0000775	chromosome, centromeric region(GO:0000775)
0.9	2.7	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.9	2.7	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.9	7.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.9	4.5	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.9	6.3	GO:0005801	cis-Golgi network(GO:0005801)
0.9	2.7	GO:0030893	cohesin complex(GO:0008278) meiotic cohesin complex(GO:0030893)
0.9	19.6	GO:0022626	cytosolic ribosome(GO:0022626)
0.9	3.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.9	2.7	GO:0045120	pronucleus(GO:0045120)
0.9	0.9	GO:0030120	vesicle coat(GO:0030120)
0.9	9.4	GO:0005624	obsolete membrane fraction(GO:0005624)
0.9	100.1	GO:0005813	centrosome(GO:0005813)
0.9	5.1	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.8	3.4	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.8	120.3	GO:0005759	mitochondrial matrix(GO:0005759)
0.8	15.9	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.8	3.3	GO:1990204	oxidoreductase complex(GO:1990204)
0.8	488.4	GO:0005730	nucleolus(GO:0005730)
0.8	864.6	GO:0005829	cytosol(GO:0005829)
0.8	1.6	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.8	29.4	GO:0005840	ribosome(GO:0005840)
0.8	2.5	GO:0048179	activin receptor complex(GO:0048179)
0.8	132.8	GO:0031966	mitochondrial membrane(GO:0031966)
0.8	0.8	GO:0001741	XY body(GO:0001741)
0.8	1.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.8	2.3	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.8	11.5	GO:0019861	obsolete flagellum(GO:0019861)
0.8	9.1	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.8	3.8	GO:0032993	protein-DNA complex(GO:0032993)
0.8	18.9	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.8	4.5	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.7	3.7	GO:0002102	podosome(GO:0002102)
0.7	4.5	GO:0016234	inclusion body(GO:0016234)
0.7	0.7	GO:0031094	platelet dense tubular network(GO:0031094)
0.7	5.1	GO:0005776	autophagosome(GO:0005776)
0.7	1.5	GO:0001891	phagocytic cup(GO:0001891)
0.7	246.2	GO:0005739	mitochondrion(GO:0005739)
0.7	33.6	GO:0005694	chromosome(GO:0005694)
0.7	1.4	GO:0043204	perikaryon(GO:0043204)
0.7	4.9	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.7	1.4	GO:0070761	pre-snoRNP complex(GO:0070761)
0.7	1.4	GO:0032590	dendrite membrane(GO:0032590)
0.7	1.4	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.7	1.3	GO:0032432	actin filament bundle(GO:0032432)
0.7	2.0	GO:0001673	male germ cell nucleus(GO:0001673) germ cell nucleus(GO:0043073)
0.7	21.3	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.7	11.9	GO:0005815	microtubule organizing center(GO:0005815)
0.7	4.0	GO:0016272	prefoldin complex(GO:0016272)
0.7	25.6	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.6	11.0	GO:0042612	MHC class I protein complex(GO:0042612)
0.6	239.6	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.6	98.4	GO:0000139	Golgi membrane(GO:0000139)
0.6	1409.7	GO:0005634	nucleus(GO:0005634)
0.6	5.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.6	1.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.6	0.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.6	12.1	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.6	5.3	GO:0030057	desmosome(GO:0030057)
0.6	1.1	GO:0042599	lamellar body(GO:0042599)
0.6	30.0	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.5	2.2	GO:0031301	integral component of organelle membrane(GO:0031301)
0.5	1.6	GO:0043679	axon terminus(GO:0043679)
0.5	0.5	GO:1902554	serine/threonine protein kinase complex(GO:1902554)
0.5	1.6	GO:0071203	WASH complex(GO:0071203)
0.5	4.8	GO:0031514	motile cilium(GO:0031514)
0.5	13.6	GO:0016459	myosin complex(GO:0016459)
0.5	3.2	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.4	15.1	GO:0098802	plasma membrane receptor complex(GO:0098802)
0.4	0.8	GO:0005577	fibrinogen complex(GO:0005577)
0.4	39.1	GO:0015630	microtubule cytoskeleton(GO:0015630)
0.4	16.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.4	0.4	GO:0005915	zonula adherens(GO:0005915)
0.4	5.0	GO:0072372	primary cilium(GO:0072372)
0.4	0.8	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.4	1.5	GO:0005667	transcription factor complex(GO:0005667)
0.4	1.1	GO:0060170	ciliary membrane(GO:0060170)
0.4	18.5	GO:0098552	side of membrane(GO:0098552)
0.4	1.8	GO:0005811	lipid particle(GO:0005811)
0.4	53.5	GO:0005794	Golgi apparatus(GO:0005794)
0.4	13.7	GO:0005768	endosome(GO:0005768)
0.3	0.3	GO:0030684	preribosome(GO:0030684)
0.3	1.3	GO:0033011	perinuclear theca(GO:0033011)
0.3	0.9	GO:0005594	collagen type IX trimer(GO:0005594)
0.3	6.4	GO:0005921	gap junction(GO:0005921)
0.3	0.6	GO:0043198	dendritic shaft(GO:0043198)
0.3	1.3	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.3	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.3	0.5	GO:0098794	postsynapse(GO:0098794)
0.2	0.7	GO:1902494	catalytic complex(GO:1902494)
0.2	2.3	GO:0043195	terminal bouton(GO:0043195)
0.2	0.6	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2	384.1	GO:0005622	intracellular(GO:0005622)
0.2	0.8	GO:0001533	cornified envelope(GO:0001533)
0.2	0.4	GO:0019867	outer membrane(GO:0019867)
0.2	0.2	GO:0014704	cell-cell adherens junction(GO:0005913) intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.1	221.8	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.2	GO:0005929	cilium(GO:0005929)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.3	15.8	GO:0035184	histone threonine kinase activity(GO:0035184)
4.9	14.8	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
4.0	12.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
4.0	16.0	GO:0008420	CTD phosphatase activity(GO:0008420)
3.9	7.8	GO:0070061	fructose binding(GO:0070061)
3.9	23.5	GO:0005521	lamin binding(GO:0005521)
3.7	11.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
3.6	18.0	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
3.6	10.8	GO:0070644	vitamin D response element binding(GO:0070644)
3.6	10.8	GO:0005049	nuclear export signal receptor activity(GO:0005049)
3.5	14.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
3.4	10.1	GO:0000400	four-way junction DNA binding(GO:0000400)
3.4	10.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
3.4	13.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
3.2	9.6	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
3.2	19.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
3.2	9.5	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
3.2	9.5	GO:0003872	6-phosphofructokinase activity(GO:0003872)
3.2	9.5	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
3.1	18.5	GO:0001727	lipid kinase activity(GO:0001727)
3.0	3.0	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705)
3.0	14.8	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
3.0	23.6	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
2.9	8.8	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
2.9	11.5	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.8	11.3	GO:0035173	histone kinase activity(GO:0035173)
2.8	8.4	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
2.7	10.9	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
2.7	24.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
2.6	21.1	GO:0005522	profilin binding(GO:0005522)
2.6	15.4	GO:0015288	porin activity(GO:0015288)
2.5	7.6	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
2.5	2.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.5	7.5	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
2.5	9.9	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.5	2.5	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
2.5	7.5	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.5	24.6	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
2.5	17.2	GO:0008494	translation activator activity(GO:0008494)
2.4	4.9	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
2.4	19.5	GO:0019992	diacylglycerol binding(GO:0019992)
2.4	7.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
2.4	7.1	GO:0051425	PTB domain binding(GO:0051425)
2.4	28.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
2.4	9.4	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
2.3	2.3	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
2.3	2.3	GO:0035591	signaling adaptor activity(GO:0035591)
2.3	9.2	GO:0043495	protein anchor(GO:0043495)
2.3	20.8	GO:0008536	Ran GTPase binding(GO:0008536)
2.3	2.3	GO:0035197	siRNA binding(GO:0035197)
2.3	38.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
2.3	4.6	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
2.3	13.7	GO:0051400	BH domain binding(GO:0051400)
2.3	6.8	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
2.3	9.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
2.3	4.5	GO:0004969	histamine receptor activity(GO:0004969)
2.3	6.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
2.3	6.8	GO:0004311	farnesyltranstransferase activity(GO:0004311)
2.2	9.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
2.2	6.6	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
2.2	8.8	GO:0004849	uridine kinase activity(GO:0004849)
2.2	6.6	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
2.2	11.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
2.2	13.0	GO:0008157	protein phosphatase 1 binding(GO:0008157)
2.2	10.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
2.2	15.1	GO:0042805	actinin binding(GO:0042805)
2.1	2.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
2.1	8.5	GO:0030911	TPR domain binding(GO:0030911)
2.1	6.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.1	8.4	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
2.1	12.6	GO:0016417	S-acyltransferase activity(GO:0016417)
2.1	14.7	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
2.1	18.8	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
2.1	37.4	GO:0043621	protein self-association(GO:0043621)
2.1	2.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.1	6.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.1	14.4	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
2.1	10.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
2.0	6.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
2.0	6.1	GO:0043398	HLH domain binding(GO:0043398)
2.0	10.1	GO:0034452	dynactin binding(GO:0034452)
2.0	4.0	GO:0032452	histone demethylase activity(GO:0032452)
2.0	13.9	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
2.0	6.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
2.0	13.9	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
2.0	7.9	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
2.0	2.0	GO:0003707	steroid hormone receptor activity(GO:0003707)
2.0	2.0	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
2.0	11.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
1.9	15.5	GO:0050700	CARD domain binding(GO:0050700)
1.9	1.9	GO:0032794	GTPase activating protein binding(GO:0032794)
1.9	5.8	GO:0001849	complement component C1q binding(GO:0001849)
1.9	9.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
1.9	5.7	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.9	13.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
1.9	7.6	GO:0004301	epoxide hydrolase activity(GO:0004301)
1.9	9.5	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.9	7.6	GO:0019788	NEDD8 transferase activity(GO:0019788)
1.9	28.3	GO:0070491	repressing transcription factor binding(GO:0070491)
1.9	5.7	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
1.9	13.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
1.9	18.7	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
1.9	9.3	GO:0009008	DNA-methyltransferase activity(GO:0009008)
1.9	9.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.9	7.4	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.9	7.4	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
1.9	5.6	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
1.9	9.3	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
1.8	14.8	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.8	1.8	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
1.8	1.8	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
1.8	7.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.8	16.2	GO:0070412	R-SMAD binding(GO:0070412)
1.8	9.0	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
1.8	3.6	GO:0004949	cannabinoid receptor activity(GO:0004949)
1.8	7.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
1.8	8.9	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.8	5.3	GO:0042608	T cell receptor binding(GO:0042608)
1.8	10.7	GO:0030507	spectrin binding(GO:0030507)
1.8	5.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
1.8	5.3	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
1.8	5.3	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
1.8	31.7	GO:0048487	beta-tubulin binding(GO:0048487)
1.8	7.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
1.8	1.8	GO:0005534	galactose binding(GO:0005534)
1.8	10.6	GO:0030274	LIM domain binding(GO:0030274)
1.8	10.5	GO:0003678	DNA helicase activity(GO:0003678)
1.8	5.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
1.7	12.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.7	12.2	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
1.7	15.7	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
1.7	8.7	GO:0019238	cyclohydrolase activity(GO:0019238)
1.7	24.3	GO:0051059	NF-kappaB binding(GO:0051059)
1.7	34.4	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
1.7	8.6	GO:0019789	SUMO transferase activity(GO:0019789)
1.7	1.7	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.7	41.0	GO:0002039	p53 binding(GO:0002039)
1.7	3.4	GO:0016803	ether hydrolase activity(GO:0016803)
1.7	5.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.7	15.3	GO:0005112	Notch binding(GO:0005112)
1.7	27.1	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
1.7	1.7	GO:0004532	exoribonuclease activity(GO:0004532)
1.7	18.5	GO:0030275	LRR domain binding(GO:0030275)
1.7	1.7	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.7	6.7	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
1.7	30.1	GO:0050699	WW domain binding(GO:0050699)
1.7	5.0	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
1.7	13.2	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
1.6	47.6	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
1.6	4.9	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.6	4.9	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.6	16.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
1.6	8.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
1.6	6.5	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.6	66.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
1.6	4.8	GO:0004517	nitric-oxide synthase activity(GO:0004517)
1.6	3.2	GO:0005113	patched binding(GO:0005113)
1.6	6.4	GO:0050815	phosphoserine binding(GO:0050815)
1.6	64.1	GO:0019210	kinase inhibitor activity(GO:0019210)
1.6	1.6	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
1.6	31.9	GO:0003682	chromatin binding(GO:0003682)
1.6	6.4	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
1.6	4.8	GO:0070735	protein-glycine ligase activity(GO:0070735)
1.6	4.7	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
1.6	4.7	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
1.6	4.7	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.6	3.1	GO:0003917	DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
1.6	9.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
1.6	4.7	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.6	12.4	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
1.6	6.2	GO:0017070	U6 snRNA binding(GO:0017070)
1.5	1.5	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
1.5	131.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
1.5	3.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
1.5	7.7	GO:0043015	gamma-tubulin binding(GO:0043015)
1.5	21.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
1.5	7.7	GO:0017069	snRNA binding(GO:0017069)
1.5	4.6	GO:0016842	amidine-lyase activity(GO:0016842)
1.5	9.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
1.5	1.5	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
1.5	6.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
1.5	6.1	GO:0004594	pantothenate kinase activity(GO:0004594)
1.5	7.6	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
1.5	52.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.5	3.0	GO:0005035	death receptor activity(GO:0005035)
1.5	10.5	GO:0043560	insulin receptor substrate binding(GO:0043560)
1.5	1.5	GO:0034618	arginine binding(GO:0034618)
1.5	4.5	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
1.5	1.5	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
1.5	6.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.5	3.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.5	10.4	GO:0031701	angiotensin receptor binding(GO:0031701)
1.5	4.5	GO:0016972	thiol oxidase activity(GO:0016972)
1.5	19.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.5	7.4	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.5	1.5	GO:0031491	nucleosome binding(GO:0031491)
1.5	8.9	GO:0030544	Hsp70 protein binding(GO:0030544)
1.5	8.9	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
1.5	4.4	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
1.5	42.8	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
1.5	19.2	GO:0031593	polyubiquitin binding(GO:0031593)
1.5	5.9	GO:0030276	clathrin binding(GO:0030276)
1.5	8.8	GO:0003688	DNA replication origin binding(GO:0003688)
1.5	10.3	GO:0030332	cyclin binding(GO:0030332)
1.5	39.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
1.5	70.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
1.5	17.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.5	4.4	GO:0008327	methyl-CpG binding(GO:0008327)
1.5	5.8	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
1.4	24.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
1.4	10.1	GO:0003724	RNA helicase activity(GO:0003724)
1.4	4.3	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.4	4.3	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.4	5.7	GO:0004340	glucokinase activity(GO:0004340)
1.4	17.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.4	8.6	GO:0016832	aldehyde-lyase activity(GO:0016832)
1.4	4.3	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
1.4	4.3	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
1.4	4.3	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
1.4	1.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
1.4	11.2	GO:0030371	translation repressor activity(GO:0030371)
1.4	14.0	GO:0004697	protein kinase C activity(GO:0004697)
1.4	11.2	GO:0001671	ATPase activator activity(GO:0001671)
1.4	9.8	GO:0032182	ubiquitin-like protein binding(GO:0032182)
1.4	5.6	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
1.4	5.6	GO:0017089	glycolipid transporter activity(GO:0017089)
1.4	11.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
1.4	5.6	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
1.4	15.3	GO:0017091	AU-rich element binding(GO:0017091)
1.4	16.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
1.4	20.7	GO:0035064	methylated histone binding(GO:0035064)
1.4	19.4	GO:0043498	obsolete cell surface binding(GO:0043498)
1.4	9.7	GO:0000339	RNA cap binding(GO:0000339)
1.4	1.4	GO:0016778	diphosphotransferase activity(GO:0016778)
1.4	6.8	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.4	40.9	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
1.4	6.8	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
1.4	8.1	GO:0050733	RS domain binding(GO:0050733)
1.4	8.1	GO:0009922	fatty acid elongase activity(GO:0009922)
1.4	2.7	GO:0004089	carbonate dehydratase activity(GO:0004089)
1.3	4.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
1.3	14.8	GO:0010181	FMN binding(GO:0010181)
1.3	9.4	GO:0004568	chitinase activity(GO:0004568)
1.3	10.8	GO:0017049	GTP-Rho binding(GO:0017049)
1.3	16.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
1.3	8.0	GO:0070402	NADPH binding(GO:0070402)
1.3	5.3	GO:0016854	racemase and epimerase activity(GO:0016854)
1.3	2.6	GO:0019855	calcium channel inhibitor activity(GO:0019855)
1.3	14.5	GO:0008175	tRNA methyltransferase activity(GO:0008175)
1.3	5.3	GO:0015252	hydrogen ion channel activity(GO:0015252)
1.3	39.4	GO:0003697	single-stranded DNA binding(GO:0003697)
1.3	1.3	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
1.3	11.7	GO:0000030	mannosyltransferase activity(GO:0000030)
1.3	3.9	GO:0032405	MutLalpha complex binding(GO:0032405)
1.3	29.8	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
1.3	3.9	GO:0045569	TRAIL binding(GO:0045569)
1.3	3.9	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.3	5.2	GO:0031014	troponin T binding(GO:0031014)
1.3	1.3	GO:0019206	nucleoside kinase activity(GO:0019206)
1.3	12.9	GO:0008199	ferric iron binding(GO:0008199)
1.3	3.9	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.3	3.8	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
1.3	10.1	GO:0017025	TBP-class protein binding(GO:0017025)
1.3	3.8	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.3	7.5	GO:0016208	AMP binding(GO:0016208)
1.3	13.8	GO:0019200	carbohydrate kinase activity(GO:0019200)
1.2	5.0	GO:0015925	galactosidase activity(GO:0015925)
1.2	1.2	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
1.2	4.9	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.2	7.4	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
1.2	28.3	GO:0016831	carboxy-lyase activity(GO:0016831)
1.2	2.5	GO:0070063	RNA polymerase binding(GO:0070063)
1.2	23.2	GO:0005484	SNAP receptor activity(GO:0005484)
1.2	4.9	GO:0070087	chromo shadow domain binding(GO:0070087)
1.2	3.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
1.2	1.2	GO:0016362	activin receptor activity, type II(GO:0016362)
1.2	4.8	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
1.2	2.4	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.2	8.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
1.2	6.0	GO:0004904	interferon receptor activity(GO:0004904)
1.2	4.8	GO:0046979	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
1.2	3.6	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.2	3.6	GO:0016882	cyclo-ligase activity(GO:0016882)
1.2	8.3	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
1.2	85.1	GO:0008565	protein transporter activity(GO:0008565)
1.2	9.5	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
1.2	1.2	GO:0032552	deoxyribonucleotide binding(GO:0032552)
1.2	3.5	GO:0043515	kinetochore binding(GO:0043515)
1.2	8.2	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
1.2	4.7	GO:0008140	cAMP response element binding protein binding(GO:0008140)
1.2	16.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.2	8.2	GO:0043014	alpha-tubulin binding(GO:0043014)
1.2	1.2	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
1.2	7.0	GO:0004000	adenosine deaminase activity(GO:0004000)
1.2	2.3	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
1.2	4.6	GO:0000104	succinate dehydrogenase activity(GO:0000104)
1.2	5.8	GO:0031685	adenosine receptor binding(GO:0031685)
1.2	2.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
1.2	3.5	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.2	8.1	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.1	4.6	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
1.1	1.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
1.1	52.8	GO:0003743	translation initiation factor activity(GO:0003743)
1.1	1.1	GO:0070410	co-SMAD binding(GO:0070410)
1.1	6.9	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
1.1	30.8	GO:0034061	DNA polymerase activity(GO:0034061)
1.1	2.3	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.1	5.7	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
1.1	12.4	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
1.1	1.1	GO:0004875	complement receptor activity(GO:0004875)
1.1	51.7	GO:0031625	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
1.1	6.7	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.1	14.5	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
1.1	37.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
1.1	13.3	GO:0005048	signal sequence binding(GO:0005048)
1.1	23.3	GO:0019003	GDP binding(GO:0019003)
1.1	12.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.1	145.1	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
1.1	13.3	GO:0070888	E-box binding(GO:0070888)
1.1	35.4	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
1.1	2.2	GO:0016530	metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
1.1	9.9	GO:0019864	IgG binding(GO:0019864)
1.1	3.3	GO:0042289	MHC class II protein binding(GO:0042289)
1.1	4.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
1.1	7.7	GO:0042288	MHC class I protein binding(GO:0042288)
1.1	24.0	GO:0004402	histone acetyltransferase activity(GO:0004402)
1.1	8.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
1.1	42.3	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
1.1	7.5	GO:0016018	cyclosporin A binding(GO:0016018)
1.1	2.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
1.1	1.1	GO:0045502	dynein binding(GO:0045502)
1.1	22.4	GO:0042393	histone binding(GO:0042393)
1.1	7.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
1.1	2.1	GO:0042605	peptide antigen binding(GO:0042605)
1.1	9.5	GO:0005246	calcium channel regulator activity(GO:0005246)
1.1	6.3	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
1.1	22.1	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
1.1	3.2	GO:0061133	endopeptidase activator activity(GO:0061133)
1.1	21.0	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.1	4.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
1.1	6.3	GO:0046790	virion binding(GO:0046790)
1.0	6.3	GO:0090599	alpha-glucosidase activity(GO:0090599)
1.0	5.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
1.0	13.5	GO:0032393	MHC class I receptor activity(GO:0032393)
1.0	5.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
1.0	14.5	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
1.0	14.5	GO:0008173	RNA methyltransferase activity(GO:0008173)
1.0	4.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
1.0	7.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.0	1.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
1.0	2.0	GO:0060590	ATPase regulator activity(GO:0060590)
1.0	3.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
1.0	2.0	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
1.0	1.0	GO:0008242	omega peptidase activity(GO:0008242)
1.0	15.9	GO:0003725	double-stranded RNA binding(GO:0003725)
1.0	83.4	GO:0051082	unfolded protein binding(GO:0051082)
1.0	2.0	GO:0031628	opioid receptor binding(GO:0031628)
1.0	8.8	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
1.0	2.9	GO:0005042	netrin receptor activity(GO:0005042)
1.0	18.5	GO:0030145	manganese ion binding(GO:0030145)
1.0	3.9	GO:0048018	receptor agonist activity(GO:0048018)
1.0	2.9	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
1.0	10.7	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
1.0	3.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.0	6.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.0	98.6	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
1.0	3.9	GO:0070097	delta-catenin binding(GO:0070097)
1.0	4.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.0	4.8	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
1.0	3.8	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
1.0	3.8	GO:0004016	adenylate cyclase activity(GO:0004016)
1.0	5.7	GO:0051920	peroxiredoxin activity(GO:0051920)
1.0	5.7	GO:0010843	obsolete promoter binding(GO:0010843)
0.9	21.7	GO:0016779	nucleotidyltransferase activity(GO:0016779)
0.9	0.9	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.9	3.8	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.9	0.9	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.9	4.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.9	3.7	GO:0005047	signal recognition particle binding(GO:0005047)
0.9	9.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.9	6.5	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.9	3.7	GO:0070513	death domain binding(GO:0070513)
0.9	1.9	GO:0008384	IkappaB kinase activity(GO:0008384)
0.9	6.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.9	1.8	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.9	30.3	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.9	2.8	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.9	9.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.9	5.5	GO:0070569	uridylyltransferase activity(GO:0070569)
0.9	56.6	GO:0004386	helicase activity(GO:0004386)
0.9	24.6	GO:0019208	phosphatase regulator activity(GO:0019208)
0.9	0.9	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.9	28.1	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.9	3.6	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.9	11.8	GO:0042826	histone deacetylase binding(GO:0042826)
0.9	1.8	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.9	8.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.9	6.3	GO:0019894	kinesin binding(GO:0019894)
0.9	112.4	GO:0016874	ligase activity(GO:0016874)
0.9	28.8	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.9	5.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.9	0.9	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.9	1.8	GO:0001846	opsonin binding(GO:0001846)
0.9	7.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.9	413.6	GO:0003723	RNA binding(GO:0003723)
0.9	6.2	GO:0015929	hexosaminidase activity(GO:0015929)
0.9	12.5	GO:0008378	galactosyltransferase activity(GO:0008378)
0.9	1.8	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.9	8.0	GO:0003993	acid phosphatase activity(GO:0003993)
0.9	4.4	GO:0019213	deacetylase activity(GO:0019213)
0.9	20.3	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.9	1.8	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.9	7.9	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.9	2.6	GO:0046527	glucosyltransferase activity(GO:0046527)
0.9	32.2	GO:0047485	protein N-terminus binding(GO:0047485)
0.9	6.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.9	10.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.9	16.4	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.9	7.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.9	1.7	GO:0051787	misfolded protein binding(GO:0051787)
0.9	5.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.8	12.7	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.8	2.5	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.8	1.7	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.8	2.5	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.8	1.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.8	33.7	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.8	5.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.8	2.5	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.8	5.8	GO:0001968	fibronectin binding(GO:0001968)
0.8	4.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.8	4.1	GO:0005123	death receptor binding(GO:0005123)
0.8	22.2	GO:0051287	NAD binding(GO:0051287)
0.8	0.8	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.8	3.3	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.8	36.8	GO:0003700	transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.8	7.3	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.8	2.4	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.8	2.4	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8	8.0	GO:0004659	prenyltransferase activity(GO:0004659)
0.8	3.2	GO:0046625	sphingolipid binding(GO:0046625)
0.8	0.8	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.8	7.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.8	1.6	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.8	1.6	GO:0004803	transposase activity(GO:0004803)
0.8	19.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.8	1.6	GO:0008518	reduced folate carrier activity(GO:0008518)
0.8	1.6	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.8	0.8	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.8	4.0	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.8	13.4	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.8	3.2	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
0.8	2.4	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.8	3.2	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.8	3.9	GO:0015923	mannosidase activity(GO:0015923)
0.8	2.4	GO:0019237	centromeric DNA binding(GO:0019237)
0.8	3.9	GO:0051010	microtubule plus-end binding(GO:0051010)
0.8	1.6	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.8	3.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.8	3.9	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.8	119.3	GO:0003924	GTPase activity(GO:0003924)
0.8	220.8	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.8	3.1	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.8	6.1	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.8	2.3	GO:0050681	androgen receptor binding(GO:0050681)
0.8	0.8	GO:0030172	troponin C binding(GO:0030172)
0.7	3.0	GO:0004046	aminoacylase activity(GO:0004046)
0.7	5.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.7	58.1	GO:0003735	structural constituent of ribosome(GO:0003735)
0.7	5.9	GO:0042171	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.7	2.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.7	2.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.7	8.0	GO:0008417	fucosyltransferase activity(GO:0008417)
0.7	2.9	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.7	9.4	GO:0015932	nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.7	2.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.7	1.4	GO:0004312	fatty acid synthase activity(GO:0004312)
0.7	5.1	GO:0004622	lysophospholipase activity(GO:0004622)
0.7	17.3	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.7	2.2	GO:0035258	steroid hormone receptor binding(GO:0035258)
0.7	1.4	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.7	2.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.7	14.1	GO:0005158	insulin receptor binding(GO:0005158)
0.7	14.1	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.7	2.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.7	9.8	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.7	2.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.7	11.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.7	10.5	GO:0004527	exonuclease activity(GO:0004527)
0.7	7.0	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.7	2.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.7	0.7	GO:0042834	peptidoglycan binding(GO:0042834)
0.7	4.8	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.7	77.6	GO:0005525	GTP binding(GO:0005525)
0.7	5.5	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.7	2.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.7	1.4	GO:0004104	cholinesterase activity(GO:0004104)
0.7	2.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.7	56.4	GO:0003712	transcription cofactor activity(GO:0003712)
0.7	2.7	GO:0008237	metallopeptidase activity(GO:0008237)
0.7	1.4	GO:0070492	oligosaccharide binding(GO:0070492)
0.7	14.2	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.7	4.7	GO:0070064	proline-rich region binding(GO:0070064)
0.7	58.3	GO:0003713	transcription coactivator activity(GO:0003713)
0.7	0.7	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.7	1.3	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.7	0.7	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.7	3.9	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.7	19.7	GO:0003690	double-stranded DNA binding(GO:0003690)
0.7	9.8	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.7	41.8	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.7	2.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.7	2.0	GO:0004180	carboxypeptidase activity(GO:0004180)
0.6	33.0	GO:0004518	nuclease activity(GO:0004518)
0.6	1.9	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.6	1.9	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.6	1.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.6	0.6	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.6	3.2	GO:0016566	obsolete specific transcriptional repressor activity(GO:0016566)
0.6	1.9	GO:0009055	electron carrier activity(GO:0009055)
0.6	2.5	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.6	0.6	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.6	845.6	GO:0003677	DNA binding(GO:0003677)
0.6	1.9	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
0.6	3.0	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.6	2.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.6	3.0	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6	5.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.6	1.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.6	1.8	GO:0070815	procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.6	14.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.6	6.4	GO:0015459	potassium channel regulator activity(GO:0015459)
0.6	8.1	GO:0005080	protein kinase C binding(GO:0005080)
0.6	1.7	GO:0004370	glycerol kinase activity(GO:0004370)
0.6	32.6	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.6	2.3	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.6	1.7	GO:0043422	protein kinase B binding(GO:0043422)
0.6	1.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.6	1.7	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.6	1.7	GO:0032451	demethylase activity(GO:0032451)
0.6	1.1	GO:0031404	chloride ion binding(GO:0031404)
0.6	1.7	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.6	3.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.5	2.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.5	10.4	GO:0016564	obsolete transcription repressor activity(GO:0016564)
0.5	1.6	GO:0033691	sialic acid binding(GO:0033691)
0.5	12.4	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.5	3.2	GO:0019829	cation-transporting ATPase activity(GO:0019829)
0.5	71.5	GO:0003676	nucleic acid binding(GO:0003676)
0.5	8.0	GO:0004177	aminopeptidase activity(GO:0004177)
0.5	2.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.5	2.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.5	3.7	GO:0016410	N-acyltransferase activity(GO:0016410)
0.5	4.6	GO:0042169	SH2 domain binding(GO:0042169)
0.5	4.6	GO:0005537	mannose binding(GO:0005537)
0.5	3.0	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5	1.5	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.5	16.1	GO:0031267	small GTPase binding(GO:0031267)
0.5	2.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.5	1.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.5	4.5	GO:0032395	MHC class II receptor activity(GO:0032395)
0.5	0.5	GO:0005131	growth hormone receptor binding(GO:0005131)
0.5	3.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.5	1.5	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors(GO:0016903)
0.5	2.4	GO:0016563	obsolete transcription activator activity(GO:0016563)
0.5	2.4	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.5	3.8	GO:0016805	dipeptidase activity(GO:0016805)
0.5	1.4	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.5	7.0	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5	4.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.5	10.7	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.5	1.4	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.5	2.7	GO:0015248	sterol transporter activity(GO:0015248)
0.5	1.8	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.4	1.3	GO:0019956	chemokine binding(GO:0019956)
0.4	2.7	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.4	1.3	GO:0019863	IgE binding(GO:0019863)
0.4	2.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.4	204.0	GO:0008270	zinc ion binding(GO:0008270)
0.4	0.4	GO:0050662	coenzyme binding(GO:0050662)
0.4	1.7	GO:0008131	primary amine oxidase activity(GO:0008131)
0.4	1.3	GO:0044877	macromolecular complex binding(GO:0044877)
0.4	7.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.4	1.3	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4	2.5	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.4	4.2	GO:0016835	carbon-oxygen lyase activity(GO:0016835)
0.4	7.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.4	21.2	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.4	80.5	GO:0030695	GTPase regulator activity(GO:0030695)
0.4	2.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.4	6.4	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.4	1.6	GO:0004629	phospholipase C activity(GO:0004629)
0.4	11.2	GO:0051015	actin filament binding(GO:0051015)
0.4	0.8	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.4	7.1	GO:0008134	transcription factor binding(GO:0008134)
0.4	5.1	GO:0022829	wide pore channel activity(GO:0022829)
0.4	2.0	GO:0016830	carbon-carbon lyase activity(GO:0016830)
0.4	11.6	GO:0004896	cytokine receptor activity(GO:0004896)
0.4	0.4	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.4	3.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4	4.5	GO:0019955	cytokine binding(GO:0019955)
0.4	0.4	GO:0030151	molybdenum ion binding(GO:0030151)
0.4	1.9	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.4	3.7	GO:0008047	enzyme activator activity(GO:0008047)
0.4	1.5	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.4	0.4	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.4	1.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.3	2.1	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.3	1.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.3	40.4	GO:0003774	motor activity(GO:0003774)
0.3	1.4	GO:0004064	arylesterase activity(GO:0004064)
0.3	0.3	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.3	0.3	GO:0043531	ADP binding(GO:0043531)
0.3	2.6	GO:0042166	acetylcholine binding(GO:0042166)
0.3	0.7	GO:0005000	vasopressin receptor activity(GO:0005000)
0.3	1.3	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3	3.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.3	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.3	4.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3	36.0	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides(GO:0016818)
0.3	0.3	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.3	0.6	GO:0016004	phospholipase activator activity(GO:0016004)
0.3	0.3	GO:0009975	cyclase activity(GO:0009975) phosphorus-oxygen lyase activity(GO:0016849)
0.3	3.3	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.3	6.3	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.3	1.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.3	1.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.3	1.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.3	3.7	GO:0005319	lipid transporter activity(GO:0005319)
0.3	1.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.3	89.0	GO:0016787	hydrolase activity(GO:0016787)
0.3	4.2	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.3	1.7	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.3	8.4	GO:0005057	receptor signaling protein activity(GO:0005057)
0.3	0.3	GO:0048185	activin binding(GO:0048185)
0.3	1.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3	27.7	GO:0001883	purine nucleoside binding(GO:0001883)
0.3	0.5	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.3	2.4	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.3	2.9	GO:0000287	magnesium ion binding(GO:0000287)
0.3	2.1	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.3	7.0	GO:0015631	tubulin binding(GO:0015631)
0.3	1.0	GO:0017080	sodium channel regulator activity(GO:0017080)
0.3	1.5	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.3	0.3	GO:0016408	C-acyltransferase activity(GO:0016408)
0.3	5.4	GO:0051213	dioxygenase activity(GO:0051213)
0.3	7.7	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.3	0.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.3	0.3	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.3	4.8	GO:0016502	G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2	3.5	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.2	3.2	GO:0003823	antigen binding(GO:0003823)
0.2	1.7	GO:0031419	cobalamin binding(GO:0031419)
0.2	1.2	GO:0016798	hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.2	1.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.2	0.2	GO:0071723	lipopeptide binding(GO:0071723)
0.2	0.2	GO:0016019	peptidoglycan receptor activity(GO:0016019) lipoteichoic acid binding(GO:0070891)
0.2	1.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.2	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.2	0.9	GO:0008170	N-methyltransferase activity(GO:0008170)
0.2	0.7	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.2	526.5	GO:0005515	protein binding(GO:0005515)
0.2	7.2	GO:0000166	nucleotide binding(GO:0000166)
0.2	0.8	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.2	0.4	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2	1.0	GO:0008430	selenium binding(GO:0008430)
0.2	0.6	GO:0042165	neurotransmitter binding(GO:0042165)
0.2	0.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.2	7.5	GO:0016746	transferase activity, transferring acyl groups(GO:0016746)
0.2	0.8	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.2	1.2	GO:0016773	phosphotransferase activity, alcohol group as acceptor(GO:0016773)
0.2	0.2	GO:0016866	intramolecular transferase activity(GO:0016866)
0.2	0.5	GO:0005549	odorant binding(GO:0005549)
0.1	1.6	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	0.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.1	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.6	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0015197	peptide transporter activity(GO:0015197)
0.1	0.2	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.1	0.3	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.6	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.1	0.6	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	0.4	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.1	48.9	GO:0005488	binding(GO:0005488)
0.1	0.2	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	6.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.0	GO:0030280	structural constituent of epidermis(GO:0030280)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.0	5.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
3.3	36.7	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
3.0	42.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
3.0	41.7	PID IL5 PATHWAY	IL5-mediated signaling events
2.8	19.9	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
2.8	8.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
2.8	152.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
2.7	23.9	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
2.7	71.7	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
2.6	20.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
2.5	40.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
2.5	2.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.4	84.4	PID BCR 5PATHWAY	BCR signaling pathway
2.4	12.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
2.4	16.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.4	16.7	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
2.3	53.6	PID PI3KCI PATHWAY	Class I PI3K signaling events
2.3	9.1	PID S1P S1P4 PATHWAY	S1P4 pathway
2.2	6.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
2.2	50.8	PID IL2 1PATHWAY	IL2-mediated signaling events
2.2	39.6	PID IFNG PATHWAY	IFN-gamma pathway
2.2	68.0	PID FOXO PATHWAY	FoxO family signaling
2.2	8.7	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
2.2	47.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
2.1	10.5	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
2.0	5.9	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
1.8	27.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
1.8	20.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.8	41.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
1.8	32.3	PID IL1 PATHWAY	IL1-mediated signaling events
1.8	107.1	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
1.8	17.8	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
1.8	3.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
1.6	1.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.6	1.6	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
1.5	21.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
1.5	7.7	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
1.5	55.1	PID MTOR 4PATHWAY	mTOR signaling pathway
1.5	9.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
1.5	43.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
1.5	15.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
1.5	8.8	PID GMCSF PATHWAY	GMCSF-mediated signaling events
1.5	14.6	PID S1P S1P1 PATHWAY	S1P1 pathway
1.4	31.4	PID BARD1 PATHWAY	BARD1 signaling events
1.4	16.9	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
1.4	23.9	PID CERAMIDE PATHWAY	Ceramide signaling pathway
1.4	4.2	ST GAQ PATHWAY	G alpha q Pathway
1.4	2.8	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
1.4	52.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
1.4	39.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
1.3	18.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
1.3	11.9	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
1.3	11.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
1.3	3.9	PID MYC PATHWAY	C-MYC pathway
1.3	28.3	PID P53 REGULATION PATHWAY	p53 pathway
1.3	29.6	PID ATR PATHWAY	ATR signaling pathway
1.3	41.0	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
1.3	6.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.3	55.9	PID P73PATHWAY	p73 transcription factor network
1.3	8.9	PID TRAIL PATHWAY	TRAIL signaling pathway
1.3	22.7	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
1.3	1.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
1.2	69.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
1.2	6.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.2	11.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
1.2	27.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
1.2	2.4	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
1.2	3.6	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
1.2	21.1	PID FANCONI PATHWAY	Fanconi anemia pathway
1.2	7.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.2	19.7	PID AURORA A PATHWAY	Aurora A signaling
1.2	10.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
1.2	36.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
1.1	27.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
1.1	33.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
1.1	28.1	PID PLK1 PATHWAY	PLK1 signaling events
1.1	11.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
1.1	20.1	PID RAC1 PATHWAY	RAC1 signaling pathway
1.1	3.3	PID ERBB4 PATHWAY	ErbB4 signaling events
1.1	5.5	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.1	8.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
1.1	23.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity
1.1	6.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
1.0	12.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.0	16.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
1.0	5.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.0	5.9	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
1.0	11.8	PID IL12 2PATHWAY	IL12-mediated signaling events
1.0	7.8	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
1.0	5.8	ST G ALPHA S PATHWAY	G alpha s Pathway
1.0	2.9	PID FAS PATHWAY	FAS (CD95) signaling pathway
1.0	11.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.9	7.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.9	7.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.9	26.7	PID CDC42 PATHWAY	CDC42 signaling events
0.9	0.9	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.9	7.0	PID ALK2 PATHWAY	ALK2 signaling events
0.9	27.8	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.9	18.8	PID E2F PATHWAY	E2F transcription factor network
0.8	5.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.8	10.9	PID ARF6 PATHWAY	Arf6 signaling events
0.8	12.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.8	13.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.8	20.2	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.8	9.6	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.8	2.4	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.8	3.8	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.8	9.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.8	2.3	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.7	12.0	PID INSULIN PATHWAY	Insulin Pathway
0.7	8.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.7	8.0	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.7	12.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.7	19.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.7	13.7	PID LKB1 PATHWAY	LKB1 signaling events
0.7	10.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.7	9.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.6	7.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.6	5.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.6	1.9	PID EPO PATHWAY	EPO signaling pathway
0.6	35.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.6	1.8	PID IL3 PATHWAY	IL3-mediated signaling events
0.6	11.5	PID AURORA B PATHWAY	Aurora B signaling
0.6	4.8	PID REELIN PATHWAY	Reelin signaling pathway
0.6	19.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.6	10.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.6	19.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.6	3.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.5	4.3	PID ATM PATHWAY	ATM pathway
0.5	0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.5	1.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.5	6.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.5	1.5	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.5	3.9	PID RHOA PATHWAY	RhoA signaling pathway
0.4	4.8	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.4	8.7	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.4	6.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.4	1.2	PID SHP2 PATHWAY	SHP2 signaling
0.4	5.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	3.8	PID BMP PATHWAY	BMP receptor signaling
0.4	3.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.4	2.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.4	3.6	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.4	5.4	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.3	2.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.3	1.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.3	3.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.3	5.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	0.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.3	0.5	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.2	0.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	1.9	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	7.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.2	1.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.2	0.6	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.2	0.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	2.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	0.7	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	1.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	5.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	1.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	1.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	0.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	1.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.1	PID IL23 PATHWAY	IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	4.4	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
3.2	56.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
3.1	6.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
3.1	46.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
2.7	32.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
2.6	7.9	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
2.6	2.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
2.5	2.5	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
2.5	39.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
2.4	46.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
2.4	9.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
2.4	2.4	REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR	Genes involved in Downstream signaling of activated FGFR
2.4	35.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
2.3	2.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
2.3	2.3	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
2.3	53.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
2.3	23.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
2.3	2.3	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
2.3	2.3	REACTOME SYNTHESIS OF DNA	Genes involved in Synthesis of DNA
2.3	11.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.2	35.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
2.2	39.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
2.2	24.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
2.2	26.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
2.2	95.3	REACTOME TCR SIGNALING	Genes involved in TCR signaling
2.1	21.5	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
2.1	19.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
2.1	33.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
2.0	2.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
2.0	36.4	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
2.0	48.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
2.0	6.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
2.0	11.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
2.0	23.5	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
1.9	23.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
1.9	51.4	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
1.8	58.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.8	7.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
1.8	16.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.8	21.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
1.8	35.6	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
1.8	14.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
1.7	13.9	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
1.7	26.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
1.7	24.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
1.7	19.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.7	6.9	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
1.7	6.9	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.7	47.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
1.7	6.8	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
1.7	11.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
1.7	1.7	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.7	50.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
1.7	23.4	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
1.7	28.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
1.6	27.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6	30.8	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
1.6	4.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
1.6	3.2	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
1.6	1.6	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
1.6	30.2	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
1.6	14.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
1.6	22.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
1.6	9.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
1.6	12.5	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
1.6	23.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
1.6	12.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
1.5	3.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
1.5	1.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
1.5	24.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
1.5	15.3	REACTOME METABOLISM OF MRNA	Genes involved in Metabolism of mRNA
1.5	6.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
1.5	31.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
1.5	16.7	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
1.5	25.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.5	12.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
1.5	13.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.5	18.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
1.5	6.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
1.5	70.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
1.5	123.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
1.4	15.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.4	8.6	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.4	8.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
1.4	12.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
1.4	14.1	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
1.4	2.8	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
1.4	16.8	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
1.4	29.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
1.4	2.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.4	16.4	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
1.3	13.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
1.3	22.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
1.3	13.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
1.3	2.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.3	17.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.3	30.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
1.3	2.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
1.3	2.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
1.3	20.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.3	23.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
1.3	11.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.3	43.8	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
1.3	39.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
1.3	2.5	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
1.3	145.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.3	1.3	REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	Genes involved in Signaling by TGF-beta Receptor Complex
1.2	44.7	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
1.2	19.8	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.2	18.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
1.2	8.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
1.2	9.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.2	4.8	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
1.2	20.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
1.2	5.9	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
1.2	3.5	REACTOME PI METABOLISM	Genes involved in PI Metabolism
1.2	10.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
1.2	4.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
1.2	53.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.2	16.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
1.1	3.4	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
1.1	18.1	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
1.1	7.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
1.1	33.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.1	14.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
1.1	1.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
1.1	2.2	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
1.1	13.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
1.1	14.1	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
1.1	23.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
1.1	49.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.1	15.9	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
1.1	49.9	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
1.1	11.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.1	25.2	REACTOME KINESINS	Genes involved in Kinesins
1.0	13.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
1.0	59.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
1.0	13.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
1.0	18.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
1.0	87.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
1.0	13.4	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
1.0	6.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
1.0	8.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
1.0	21.5	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
1.0	4.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
1.0	18.0	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.0	52.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
1.0	2.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
1.0	129.4	REACTOME TRANSLATION	Genes involved in Translation
1.0	15.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
1.0	3.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.0	27.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
1.0	21.1	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
1.0	6.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.9	1.9	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.9	18.8	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.9	1.9	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.9	7.5	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.9	8.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.9	26.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.9	17.7	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.9	0.9	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.9	0.9	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.9	14.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.9	14.8	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.9	11.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.9	11.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.9	12.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.9	12.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.9	1.7	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.9	6.8	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.8	18.6	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.8	5.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.8	40.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8	1.7	REACTOME NFKB AND MAP KINASES ACTIVATION MEDIATED BY TLR4 SIGNALING REPERTOIRE	Genes involved in NFkB and MAP kinases activation mediated by TLR4 signaling repertoire
0.8	5.8	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.8	10.6	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.8	10.6	REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.8	6.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.8	45.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.8	4.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.8	12.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.8	18.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.8	4.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.7	20.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.7	2.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.7	1.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.7	15.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.7	15.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.7	22.3	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.7	5.5	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.7	4.7	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.7	29.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.7	5.3	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.7	5.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.6	21.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.6	1.9	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.6	12.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.6	1.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.6	8.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.6	20.4	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.6	14.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.6	4.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.6	14.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.6	2.4	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.6	5.4	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.6	4.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.6	18.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.6	11.7	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.5	6.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.5	0.5	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.5	0.5	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.5	9.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.5	2.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.5	6.8	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.5	4.6	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.5	1.0	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.5	2.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.5	1.0	REACTOME SIGNALING BY NOTCH	Genes involved in Signaling by NOTCH
0.5	4.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.5	17.9	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.5	7.1	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.5	117.5	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.5	0.9	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.5	6.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.4	0.9	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.4	3.9	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.4	9.9	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.4	27.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.4	0.9	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.4	11.4	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.4	4.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.4	5.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.4	4.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.4	3.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	4.0	REACTOME MEIOSIS	Genes involved in Meiosis
0.3	4.5	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.3	1.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.3	3.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	2.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	13.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.3	0.3	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
0.3	0.9	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.3	1.7	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.3	3.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.3	3.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	7.0	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.3	6.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.3	1.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.3	3.0	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3	4.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	2.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	3.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.2	18.6	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.2	5.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	1.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	1.8	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.2	9.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	1.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.2	3.8	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2	0.9	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
0.1	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.1	0.5	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.1	6.3	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	2.7	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.1	1.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	0.7	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.6	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle
0.1	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.4	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1	0.2	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.1	3.3	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.4	REACTOME OPSINS	Genes involved in Opsins
0.0	0.0	REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	Genes involved in Cytokine Signaling in Immune system
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.8	REACTOME DEFENSINS	Genes involved in Defensins
0.0	5.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.1	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)

Results for ZNF711_TFAP2A_TFAP2D

Z-value: 11.68

Motif logo

Transcription factors associated with ZNF711_TFAP2A_TFAP2D

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ZNF711_TFAP2A_TFAP2D motif across conditions

Conditions sorted by the z-value of the ZNF711_TFAP2A_TFAP2D motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF711_TFAP2A_TFAP2D

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: