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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF784

Z-value: 1.72

Motif logo

Transcription factors associated with ZNF784

Gene Symbol	Gene ID	Gene Info
ZNF784 Ensembl NCBI GeneCards UniProt	ENSG00000179922.5	ZNF784

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZNF784	chr19_56136460_56136611	568	0.492768	0.52	1.5e-01	Click!
ZNF784	chr19_56132551_56132702	3306	0.089935	-0.44	2.3e-01	Click!
ZNF784	chr19_56132152_56132303	3705	0.085080	-0.40	2.9e-01	Click!
ZNF784	chr19_56135787_56135955	61	0.922893	0.33	3.8e-01	Click!
ZNF784	chr19_56135238_56135556	535	0.519693	-0.16	6.8e-01	Click!

Activity of the ZNF784 motif across conditions

Conditions sorted by the z-value of the ZNF784 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_33864237_33864745	1.66	SLFN12L	schlafen family member 12-like	389	0.76
chr3_121379556_121379755	1.40	HCLS1	hematopoietic cell-specific Lyn substrate 1	90	0.96
chr16_3116517_3116777	1.40	IL32	interleukin 32	834	0.3
chr1_198608305_198608501	1.38	PTPRC	protein tyrosine phosphatase, receptor type, C	111	0.98
chr10_5334923_5335219	1.33	AKR1C7P	aldo-keto reductase family 1, member C7, pseudogene	4638	0.23
chr1_207094900_207095227	1.22	FAIM3	Fas apoptotic inhibitory molecule 3	149	0.94
chr7_45067326_45068016	1.15	CCM2	cerebral cavernous malformation 2	400	0.81
chr10_11209293_11209598	1.13	CELF2	CUGBP, Elav-like family member 2	1954	0.35
chr22_37542366_37542517	1.13	IL2RB	interleukin 2 receptor, beta	3589	0.14
chr10_135202564_135202912	1.08	RP11-108K14.8	Mitochondrial GTPase 1	1600	0.18
chr20_62368950_62369101	1.05	LIME1	Lck interacting transmembrane adaptor 1	388	0.53
chr13_52398191_52398536	1.02	RP11-327P2.5		19930	0.17
chr19_40447118_40447269	1.01	FCGBP	Fc fragment of IgG binding protein	6660	0.17
chr12_56415966_56416141	0.97	IKZF4	IKAROS family zinc finger 4 (Eos)	953	0.34
chr16_85932806_85932957	0.97	IRF8	interferon regulatory factor 8	112	0.97
chr11_6767215_6767876	0.97	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2	22741	0.11
chr14_92332597_92332814	0.94	TC2N	tandem C2 domains, nuclear	1168	0.51
chr1_100887352_100887656	0.94	ENSG00000216067	.	43173	0.14
chr1_156458657_156458808	0.93	MEF2D	myocyte enhancer factor 2D	1659	0.26
chr10_63663177_63663552	0.92	ARID5B	AT rich interactive domain 5B (MRF1-like)	2305	0.38
chr22_26823969_26824219	0.92	ASPHD2	aspartate beta-hydroxylase domain containing 2	1145	0.46
chr6_32407696_32407883	0.87	HLA-DRA	major histocompatibility complex, class II, DR alpha	134	0.95
chr11_60850090_60850241	0.86	CD5	CD5 molecule	19702	0.16
chrY_16636064_16636659	0.86	NLGN4Y	neuroligin 4, Y-linked	93	0.99
chr2_175462692_175462904	0.85	WIPF1	WAS/WASL interacting protein family, member 1	136	0.96
chr2_43448588_43448818	0.84	ZFP36L2	ZFP36 ring finger protein-like 2	5045	0.26
chr1_150737696_150737976	0.83	CTSS	cathepsin S	432	0.77
chr21_32557466_32557617	0.82	TIAM1	T-cell lymphoma invasion and metastasis 1	55002	0.16
chr16_50303381_50303532	0.82	ADCY7	adenylate cyclase 7	2994	0.28
chr12_15699329_15699635	0.79	PTPRO	protein tyrosine phosphatase, receptor type, O	196	0.97
chr21_36715747_36715917	0.79	RUNX1	runt-related transcription factor 1	294191	0.01
chr1_92951290_92951613	0.76	GFI1	growth factor independent 1 transcription repressor	177	0.97
chr3_151917198_151917573	0.75	MBNL1	muscleblind-like splicing regulator 1	68444	0.12
chr5_150636818_150636969	0.75	GM2A	GM2 ganglioside activator	2467	0.28
chr2_148602569_148602812	0.75	ACVR2A	activin A receptor, type IIA	505	0.82
chr11_118209630_118210055	0.74	CD3D	CD3d molecule, delta (CD3-TCR complex)	1810	0.22
chr8_8727283_8727434	0.73	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	23797	0.18
chr13_97874593_97875664	0.70	MBNL2	muscleblind-like splicing regulator 2	519	0.87
chr20_31099035_31099434	0.69	C20orf112	chromosome 20 open reading frame 112	24	0.98
chr21_43186131_43186315	0.69	RIPK4	receptor-interacting serine-threonine kinase 4	105	0.97
chr12_51717169_51717830	0.68	BIN2	bridging integrator 2	400	0.82
chr11_128395074_128395489	0.67	RP11-1007G5.2		756	0.69
chr2_106043022_106043173	0.67	FHL2	four and a half LIM domains 2	11855	0.23
chr4_89742277_89742465	0.66	FAM13A	family with sequence similarity 13, member A	1981	0.43
chr5_1108899_1109050	0.66	SLC12A7	solute carrier family 12 (potassium/chloride transporter), member 7	3176	0.24
chr10_104210626_104210853	0.65	ENSG00000269609	.	351	0.57
chr13_46754139_46754322	0.65	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	2229	0.26
chr17_36864246_36864397	0.65	CTB-58E17.3		1807	0.14
chr3_124303143_124303518	0.64	KALRN	kalirin, RhoGEF kinase	176	0.97
chrX_51137751_51137902	0.64	RP11-348F1.3		1488	0.45
chr2_242800719_242801011	0.63	PDCD1	programmed cell death 1	195	0.9
chr16_54026157_54026308	0.63	RP11-357N13.2		7649	0.19
chrX_154417087_154417278	0.62	VBP1	von Hippel-Lindau binding protein 1	8102	0.19
chr9_130736579_130736730	0.61	FAM102A	family with sequence similarity 102, member A	6138	0.12
chr2_191751090_191751325	0.61	AC005540.3		4422	0.24
chr19_46219682_46220065	0.61	FBXO46	F-box protein 46	1337	0.23
chr15_25200210_25200938	0.61	SNURF	SNRPN upstream reading frame protein	413	0.41
chr1_9031254_9031405	0.60	ENSG00000265141	.	8604	0.17
chr1_209942353_209942874	0.59	TRAF3IP3	TRAF3 interacting protein 3	653	0.63
chr9_140356804_140356997	0.59	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor	3114	0.16
chr6_111302519_111302780	0.59	RPF2	ribosome production factor 2 homolog (S. cerevisiae)	569	0.68
chr7_13097458_13097609	0.58	ENSG00000222974	.	181224	0.03
chr14_22963855_22964006	0.58	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	7759	0.1
chr4_100738641_100738957	0.58	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	796	0.72
chr5_133451742_133452000	0.57	TCF7	transcription factor 7 (T-cell specific, HMG-box)	555	0.8
chr1_198609469_198609717	0.57	PTPRC	protein tyrosine phosphatase, receptor type, C	1301	0.54
chr14_21736745_21736945	0.57	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	35	0.97
chr1_10759853_10760004	0.56	CASZ1	castor zinc finger 1	54795	0.12
chr1_60162288_60162439	0.56	ENSG00000266150	.	36605	0.2
chr7_30634096_30634338	0.55	GARS	glycyl-tRNA synthetase	80	0.61
chrX_70917395_70917655	0.55	ENSG00000221684	.	61780	0.11
chr6_144732729_144732880	0.55	UTRN	utrophin	67567	0.13
chr1_26872331_26872899	0.55	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	272	0.88
chr13_28715875_28716136	0.55	PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	2835	0.24
chr4_156760399_156760658	0.55	TDO2	tryptophan 2,3-dioxygenase	15386	0.21
chr17_47287660_47288689	0.54	GNGT2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	238	0.65
chr1_154915200_154915451	0.54	PMVK	phosphomevalonate kinase	5858	0.09
chrX_106362200_106362401	0.53	RBM41	RNA binding motif protein 41	243	0.94
chr8_97533683_97533834	0.53	SDC2	syndecan 2	27522	0.23
chr7_154719533_154719892	0.53	PAXIP1-AS2	PAXIP1 antisense RNA 2	515	0.78
chr15_89009981_89010294	0.53	MRPL46	mitochondrial ribosomal protein L46	513	0.47
chr17_19280691_19280938	0.53	MAPK7	mitogen-activated protein kinase 7	220	0.65
chr7_155437664_155437928	0.52	RBM33	RNA binding motif protein 33	400	0.67
chr7_64541108_64541627	0.52	ENSG00000207062	.	10451	0.15
chr13_99226843_99226994	0.51	STK24	serine/threonine kinase 24	2199	0.3
chr11_116644068_116644415	0.51	AP006216.10		136	0.83
chr19_16379423_16379574	0.51	CTD-2562J15.6		24888	0.13
chr3_185652121_185652403	0.51	TRA2B	transformer 2 beta homolog (Drosophila)	3539	0.25
chr18_60984919_60985484	0.51	BCL2	B-cell CLL/lymphoma 2	844	0.57
chrX_71003427_71003880	0.50	ENSG00000221684	.	24348	0.23
chr20_30262987_30263252	0.50	RP11-243J16.7		10900	0.13
chr11_8929144_8929295	0.50	ST5	suppression of tumorigenicity 5	3279	0.14
chr12_111867666_111868155	0.49	SH2B3	SH2B adaptor protein 3	4756	0.21
chr4_103423579_103423896	0.49	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	682	0.61
chrY_15017679_15018174	0.49	DDX3Y	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	277	0.95
chr11_65647291_65647461	0.48	CTSW	cathepsin W	47	0.93
chr7_128379466_128379711	0.48	CALU	calumenin	130	0.94
chrX_111125134_111125285	0.48	TRPC5OS	TRPC5 opposite strand	84	0.98
chr12_1920714_1920865	0.48	CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	97	0.97
chr11_67204819_67205147	0.48	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein	555	0.47
chr19_50879744_50879984	0.48	NR1H2	nuclear receptor subfamily 1, group H, member 2	134	0.91
chr8_26162809_26162960	0.47	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	11885	0.26
chr2_106407332_106407557	0.47	NCK2	NCK adaptor protein 2	25571	0.24
chr1_8685789_8685940	0.47	RERE	arginine-glutamic acid dipeptide (RE) repeats	1425	0.54
chr13_50158821_50159403	0.47	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	602	0.77
chr2_85076559_85076967	0.47	TRABD2A	TraB domain containing 2A	31443	0.16
chr11_67186882_67187131	0.47	PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	1646	0.15
chr1_100715442_100715812	0.47	DBT	dihydrolipoamide branched chain transacylase E2	237	0.9
chr21_36418295_36418575	0.47	RUNX1	runt-related transcription factor 1	3027	0.41
chr21_34142699_34142850	0.47	PAXBP1	PAX3 and PAX7 binding protein 1	1205	0.34
chr19_12847748_12847986	0.47	ASNA1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	86	0.91
chr10_64134972_64135123	0.46	ZNF365	zinc finger protein 365	256	0.94
chr19_12906733_12906884	0.46	CTD-2659N19.10		829	0.32
chr1_50513511_50513662	0.46	ELAVL4	ELAV like neuron-specific RNA binding protein 4	100	0.97
chr3_16926768_16927235	0.46	PLCL2	phospholipase C-like 2	549	0.84
chr18_9404902_9405053	0.46	RALBP1	ralA binding protein 1	70030	0.08
chr20_61554036_61554389	0.45	DIDO1	death inducer-obliterator 1	3609	0.18
chr3_129034345_129034731	0.45	H1FX-AS1	H1FX antisense RNA 1	175	0.82
chrX_70838155_70838405	0.45	CXCR3	chemokine (C-X-C motif) receptor 3	80	0.97
chr1_168523425_168523576	0.45	XCL2	chemokine (C motif) ligand 2	10265	0.23
chr6_150038866_150039094	0.45	LATS1	large tumor suppressor kinase 1	190	0.93
chr9_20622216_20622410	0.45	MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	201	0.95
chr3_172232547_172232820	0.44	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	8582	0.25
chr4_151995452_151995603	0.44	RPS3A	ribosomal protein S3A	25198	0.14
chr10_5855917_5856253	0.44	GDI2	GDP dissociation inhibitor 2	207	0.94
chr2_87214834_87214999	0.43	PLGLB1	plasminogen-like B1	34059	0.19
chr4_6576981_6577196	0.43	MAN2B2	mannosidase, alpha, class 2B, member 2	146	0.96
chr19_58898981_58899504	0.43	RPS5	ribosomal protein S5	586	0.41
chr15_93457570_93457977	0.43	CHD2	chromodomain helicase DNA binding protein 2	10070	0.2
chr14_22972748_22972969	0.43	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	16687	0.09
chr2_88081579_88081730	0.42	PLGLB2	plasminogen-like B2	34048	0.19
chr11_17298295_17298504	0.42	NUCB2	nucleobindin 2	21	0.98
chr17_60802287_60802509	0.42	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	11480	0.17
chr13_113807206_113807543	0.42	PROZ	protein Z, vitamin K-dependent plasma glycoprotein	5594	0.13
chr7_26192485_26193339	0.42	NFE2L3	nuclear factor, erythroid 2-like 3	1052	0.53
chr6_159420910_159421511	0.42	RSPH3	radial spoke 3 homolog (Chlamydomonas)	9	0.82
chr7_99096274_99096688	0.42	ZNF394	zinc finger protein 394	1406	0.25
chr12_55373639_55373790	0.42	TESPA1	thymocyte expressed, positive selection associated 1	1908	0.39
chr11_111798023_111798431	0.42	DIXDC1	DIX domain containing 1	359	0.67
chr16_2015079_2015314	0.42	ENSG00000255198	.	11	0.78
chr1_226068030_226068371	0.42	TMEM63A	transmembrane protein 63A	1869	0.24
chr12_4938445_4938596	0.41	RP3-377H17.2		9601	0.2
chr4_38666789_38667086	0.41	RP11-617D20.1		433	0.48
chr2_110595491_110595642	0.41	RGPD5	RANBP2-like and GRIP domain containing 5	43304	0.17
chr14_64107873_64108536	0.41	WDR89	WD repeat domain 89	79	0.96
chr2_108489338_108489489	0.41	RGPD4	RANBP2-like and GRIP domain containing 4	46020	0.19
chr19_48835680_48835937	0.41	EMP3	epithelial membrane protein 3	6943	0.11
chr9_80523811_80523962	0.41	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	85971	0.1
chr17_38559088_38559385	0.41	ENSG00000222881	.	11646	0.11
chr11_124618587_124618738	0.41	RP11-677M14.2		2429	0.15
chr19_50651113_50651549	0.41	IZUMO2	IZUMO family member 2	15082	0.15
chr6_11382632_11382872	0.40	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	171	0.97
chr3_39321282_39321554	0.40	CX3CR1	chemokine (C-X3-C motif) receptor 1	107	0.97
chr12_14518062_14518320	0.40	ATF7IP	activating transcription factor 7 interacting protein	425	0.88
chr8_22463688_22463839	0.40	CCAR2	cell cycle and apoptosis regulator 2	350	0.76
chr10_106027925_106028215	0.40	ENSG00000266852	.	107	0.87
chr2_169458843_169458994	0.40	ENSG00000199348	.	4088	0.27
chr2_113145556_113145707	0.40	RGPD8	RANBP2-like and GRIP domain containing 8	45465	0.15
chr1_198637715_198637866	0.39	RP11-553K8.5		1600	0.47
chr12_54811406_54811839	0.39	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	1622	0.22
chr6_26442341_26442492	0.39	BTN3A3	butyrophilin, subfamily 3, member A3	1630	0.25
chr15_68570739_68571112	0.39	FEM1B	fem-1 homolog b (C. elegans)	784	0.64
chr1_43803771_43803922	0.39	MPL	myeloproliferative leukemia virus oncogene	326	0.8
chr1_21859764_21859915	0.39	ALPL	alkaline phosphatase, liver/bone/kidney	17933	0.19
chr6_29692032_29692183	0.39	HLA-F	major histocompatibility complex, class I, F	291	0.87
chr2_111291029_111291180	0.39	RGPD6	RANBP2-like and GRIP domain containing 6	483	0.83
chr9_127950035_127950361	0.39	PPP6C	protein phosphatase 6, catalytic subunit	1864	0.3
chr16_80838686_80839030	0.39	CDYL2	chromodomain protein, Y-like 2	632	0.79
chr21_30397725_30398151	0.39	RP1-100J12.1		727	0.42
chr5_134181747_134182027	0.38	C5orf24	chromosome 5 open reading frame 24	43	0.97
chr20_13764930_13765215	0.38	ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	460	0.52
chr5_154137578_154138162	0.38	LARP1	La ribonucleoprotein domain family, member 1	1136	0.49
chr1_152162233_152162399	0.38	FLG-AS1	FLG antisense RNA 1	489	0.77
chr6_134861028_134861179	0.38	SGK1	serum/glucocorticoid regulated kinase 1	221853	0.02
chr2_28616306_28616795	0.37	FOSL2	FOS-like antigen 2	825	0.43
chr22_50523508_50523892	0.37	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1	12	0.97
chr11_559952_560103	0.37	RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	377	0.43
chr3_141121878_141122254	0.37	ZBTB38	zinc finger and BTB domain containing 38	406	0.88
chr2_106367063_106367214	0.37	NCK2	NCK adaptor protein 2	4950	0.33
chr3_160167041_160167544	0.37	TRIM59	tripartite motif containing 59	109	0.96
chr16_8715324_8715502	0.37	METTL22	methyltransferase like 22	127	0.97
chr19_47125438_47125589	0.37	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	2781	0.13
chr10_43902220_43902565	0.37	HNRNPF	heterogeneous nuclear ribonucleoprotein F	875	0.54
chr9_134405336_134405487	0.37	UCK1	uridine-cytidine kinase 1	1155	0.4
chr11_67176589_67176876	0.37	TBC1D10C	TBC1 domain family, member 10C	5072	0.07
chr2_231191950_231192650	0.36	SP140L	SP140 nuclear body protein-like	315	0.92
chr1_170536747_170536898	0.36	RP11-576I22.2		35034	0.18
chr16_3660969_3661192	0.36	SLX4	SLX4 structure-specific endonuclease subunit	519	0.73
chr19_10675577_10675931	0.36	KRI1	KRI1 homolog (S. cerevisiae)	912	0.35
chr1_212588032_212588228	0.35	TMEM206	transmembrane protein 206	107	0.96
chr2_118572851_118573368	0.35	DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	883	0.63
chr2_98261858_98262243	0.35	COX5B	cytochrome c oxidase subunit Vb	453	0.77
chr9_130692852_130693086	0.35	PIP5KL1	phosphatidylinositol-4-phosphate 5-kinase-like 1	107	0.92
chr2_204735521_204735672	0.35	CTLA4	cytotoxic T-lymphocyte-associated protein 4	641	0.79
chr3_71630406_71630763	0.35	FOXP1	forkhead box P1	2320	0.31
chr1_59164702_59165010	0.35	MYSM1	Myb-like, SWIRM and MPN domains 1	908	0.62
chr12_66524690_66525029	0.35	LLPH	LLP homolog, long-term synaptic facilitation (Aplysia)	311	0.49
chr1_32721190_32721341	0.35	LCK	lymphocyte-specific protein tyrosine kinase	4390	0.1
chr9_130536234_130536385	0.35	SH2D3C	SH2 domain containing 3C	2592	0.13
chr4_4290910_4291202	0.35	LYAR	Ly1 antibody reactive	692	0.48

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF784

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.4	1.3	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.4	1.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2	0.7	GO:0008049	male courtship behavior(GO:0008049)
0.2	0.6	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.2	0.6	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.8	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	1.0	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.4	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1	0.3	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.1	0.4	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.4	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.4	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.3	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.3	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.1	0.5	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.4	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	1.2	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.2	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.2	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.1	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.3	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.5	GO:0006013	mannose metabolic process(GO:0006013)
0.1	0.2	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.3	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	1.4	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.1	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.5	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.2	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.1	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.2	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.2	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.2	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	0.2	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.4	GO:1904377	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.3	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.6	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.7	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.2	GO:0021554	optic nerve development(GO:0021554)
0.0	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.5	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.5	GO:0007379	segment specification(GO:0007379)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.3	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.2	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.3	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.3	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.3	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.5	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	1.0	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.0	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.0	0.2	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:1901021	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	1.2	GO:0006968	cellular defense response(GO:0006968)
0.0	0.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.4	GO:0009268	response to pH(GO:0009268)
0.0	0.2	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.5	GO:2000117	negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.3	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.2	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0045634	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.3	GO:1902579	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.2	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.2	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.5	GO:0007602	phototransduction(GO:0007602)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.0	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.3	GO:0051225	spindle assembly(GO:0051225)
0.0	0.1	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.6	GO:0051017	actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0	0.0	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.0	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.4	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.0	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.7	GO:0072431	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.0	GO:0006882	cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.0	GO:0003417	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	1.7	GO:0006470	protein dephosphorylation(GO:0006470)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.2	GO:0008542	visual learning(GO:0008542)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.2	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0010165	response to X-ray(GO:0010165)
0.0	0.0	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.1	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
0.0	0.5	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.6	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.1	GO:1903578	regulation of glycolytic process(GO:0006110) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	0.5	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	1.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.4	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.3	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0000800	lateral element(GO:0000800)
0.1	0.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.6	GO:0045120	pronucleus(GO:0045120)
0.1	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.3	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	1.0	GO:0005884	actin filament(GO:0005884)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.5	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.8	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.2	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.5	GO:0032420	stereocilium(GO:0032420)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	2.2	GO:0005925	focal adhesion(GO:0005925)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.4	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.4	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:1990391	mismatch repair complex(GO:0032300) DNA repair complex(GO:1990391)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.0	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.0	GO:0010369	chromocenter(GO:0010369)
0.0	0.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	1.0	GO:0005840	ribosome(GO:0005840)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	1.2	GO:0009897	external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0034711	inhibin binding(GO:0034711)
0.2	2.7	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	1.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	0.4	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	0.5	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.8	GO:0005522	profilin binding(GO:0005522)
0.1	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0032356	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.1	0.3	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.4	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.2	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.4	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0051400	BH domain binding(GO:0051400)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.3	GO:0001846	opsonin binding(GO:0001846)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.5	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.2	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.6	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.4	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.4	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.3	GO:0030547	receptor inhibitor activity(GO:0030547)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.4	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.7	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.3	GO:0046970	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.6	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	1.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.2	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	1.2	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.5	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	1.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.4	GO:0019783	ubiquitin-like protein-specific protease activity(GO:0019783)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.4	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.3	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	1.1	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.0	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.3	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.0	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.5	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.3	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.7	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.2	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.5	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.9	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	1.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	2.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	1.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	1.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.5	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.4	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.6	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	1.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	1.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	1.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.5	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	1.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.6	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.3	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.3	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1