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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for ZNF784

Z-value: 1.72

Motif logo

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Transcription factors associated with ZNF784

Gene Symbol Gene ID Gene Info
ZNF784
ENSG00000179922.5 zinc finger protein 784

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_56136460_56136611ZNF7845680.4927680.521.5e-01Click!
chr19_56132551_56132702ZNF78433060.089935-0.442.3e-01Click!
chr19_56132152_56132303ZNF78437050.085080-0.402.9e-01Click!
chr19_56135787_56135955ZNF784610.9228930.333.8e-01Click!
chr19_56135238_56135556ZNF7845350.519693-0.166.8e-01Click!

Activity of the ZNF784 motif across conditions

Conditions sorted by the z-value of the ZNF784 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_33864237_33864745 1.66 SLFN12L
 schlafen family member 12-like
 389
 0.76
chr3_121379556_121379755 1.40 HCLS1
 hematopoietic cell-specific Lyn substrate 1
 90
 0.96
chr16_3116517_3116777 1.40 IL32
 interleukin 32
 834
 0.3
chr1_198608305_198608501 1.38 PTPRC
 protein tyrosine phosphatase, receptor type, C
 111
 0.98
chr10_5334923_5335219 1.33 AKR1C7P
 aldo-keto reductase family 1, member C7, pseudogene
 4638
 0.23
chr1_207094900_207095227 1.22 FAIM3
 Fas apoptotic inhibitory molecule 3
 149
 0.94
chr7_45067326_45068016 1.15 CCM2
 cerebral cavernous malformation 2
 400
 0.81
chr10_11209293_11209598 1.13 CELF2
 CUGBP, Elav-like family member 2
 1954
 0.35
chr22_37542366_37542517 1.13 IL2RB
 interleukin 2 receptor, beta
 3589
 0.14
chr10_135202564_135202912 1.08 RP11-108K14.8
 Mitochondrial GTPase 1
 1600
 0.18
chr20_62368950_62369101 1.05 LIME1
 Lck interacting transmembrane adaptor 1
 388
 0.53
chr13_52398191_52398536 1.02 RP11-327P2.5
19930
 0.17
chr19_40447118_40447269 1.01 FCGBP
 Fc fragment of IgG binding protein
 6660
 0.17
chr12_56415966_56416141 0.97 IKZF4
 IKAROS family zinc finger 4 (Eos)
 953
 0.34
chr16_85932806_85932957 0.97 IRF8
 interferon regulatory factor 8
 112
 0.97
chr11_6767215_6767876 0.97 OR2AG2
 olfactory receptor, family 2, subfamily AG, member 2
 22741
 0.11
chr14_92332597_92332814 0.94 TC2N
 tandem C2 domains, nuclear
 1168
 0.51
chr1_100887352_100887656 0.94 ENSG00000216067
 .
 43173
 0.14
chr1_156458657_156458808 0.93 MEF2D
 myocyte enhancer factor 2D
 1659
 0.26
chr10_63663177_63663552 0.92 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 2305
 0.38
chr22_26823969_26824219 0.92 ASPHD2
 aspartate beta-hydroxylase domain containing 2
 1145
 0.46
chr6_32407696_32407883 0.87 HLA-DRA
 major histocompatibility complex, class II, DR alpha
 134
 0.95
chr11_60850090_60850241 0.86 CD5
 CD5 molecule
 19702
 0.16
chrY_16636064_16636659 0.86 NLGN4Y
 neuroligin 4, Y-linked
 93
 0.99
chr2_175462692_175462904 0.85 WIPF1
 WAS/WASL interacting protein family, member 1
 136
 0.96
chr2_43448588_43448818 0.84 ZFP36L2
 ZFP36 ring finger protein-like 2
 5045
 0.26
chr1_150737696_150737976 0.83 CTSS
 cathepsin S
 432
 0.77
chr21_32557466_32557617 0.82 TIAM1
 T-cell lymphoma invasion and metastasis 1
 55002
 0.16
chr16_50303381_50303532 0.82 ADCY7
 adenylate cyclase 7
 2994
 0.28
chr12_15699329_15699635 0.79 PTPRO
 protein tyrosine phosphatase, receptor type, O
 196
 0.97
chr21_36715747_36715917 0.79 RUNX1
 runt-related transcription factor 1
 294191
 0.01
chr1_92951290_92951613 0.76 GFI1
 growth factor independent 1 transcription repressor
 177
 0.97
chr3_151917198_151917573 0.75 MBNL1
 muscleblind-like splicing regulator 1
 68444
 0.12
chr5_150636818_150636969 0.75 GM2A
 GM2 ganglioside activator
 2467
 0.28
chr2_148602569_148602812 0.75 ACVR2A
 activin A receptor, type IIA
 505
 0.82
chr11_118209630_118210055 0.74 CD3D
 CD3d molecule, delta (CD3-TCR complex)
 1810
 0.22
chr8_8727283_8727434 0.73 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 23797
 0.18
chr13_97874593_97875664 0.70 MBNL2
 muscleblind-like splicing regulator 2
 519
 0.87
chr20_31099035_31099434 0.69 C20orf112
 chromosome 20 open reading frame 112
 24
 0.98
chr21_43186131_43186315 0.69 RIPK4
 receptor-interacting serine-threonine kinase 4
 105
 0.97
chr12_51717169_51717830 0.68 BIN2
 bridging integrator 2
 400
 0.82
chr11_128395074_128395489 0.67 RP11-1007G5.2
756
 0.69
chr2_106043022_106043173 0.67 FHL2
 four and a half LIM domains 2
 11855
 0.23
chr4_89742277_89742465 0.66 FAM13A
 family with sequence similarity 13, member A
 1981
 0.43
chr5_1108899_1109050 0.66 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
 3176
 0.24
chr10_104210626_104210853 0.65 ENSG00000269609
 .
 351
 0.57
chr13_46754139_46754322 0.65 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 2229
 0.26
chr17_36864246_36864397 0.65 CTB-58E17.3
1807
 0.14
chr3_124303143_124303518 0.64 KALRN
 kalirin, RhoGEF kinase
 176
 0.97
chrX_51137751_51137902 0.64 RP11-348F1.3
1488
 0.45
chr2_242800719_242801011 0.63 PDCD1
 programmed cell death 1
 195
 0.9
chr16_54026157_54026308 0.63 RP11-357N13.2
7649
 0.19
chrX_154417087_154417278 0.62 VBP1
 von Hippel-Lindau binding protein 1
 8102
 0.19
chr9_130736579_130736730 0.61 FAM102A
 family with sequence similarity 102, member A
 6138
 0.12
chr2_191751090_191751325 0.61 AC005540.3
4422
 0.24
chr19_46219682_46220065 0.61 FBXO46
 F-box protein 46
 1337
 0.23
chr15_25200210_25200938 0.61 SNURF
 SNRPN upstream reading frame protein
 413
 0.41
chr1_9031254_9031405 0.60 ENSG00000265141
 .
 8604
 0.17
chr1_209942353_209942874 0.59 TRAF3IP3
 TRAF3 interacting protein 3
 653
 0.63
chr9_140356804_140356997 0.59 NSMF
 NMDA receptor synaptonuclear signaling and neuronal migration factor
 3114
 0.16
chr6_111302519_111302780 0.59 RPF2
 ribosome production factor 2 homolog (S. cerevisiae)
 569
 0.68
chr7_13097458_13097609 0.58 ENSG00000222974
 .
 181224
 0.03
chr14_22963855_22964006 0.58 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 7759
 0.1
chr4_100738641_100738957 0.58 DAPP1
 dual adaptor of phosphotyrosine and 3-phosphoinositides
 796
 0.72
chr5_133451742_133452000 0.57 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 555
 0.8
chr1_198609469_198609717 0.57 PTPRC
 protein tyrosine phosphatase, receptor type, C
 1301
 0.54
chr14_21736745_21736945 0.57 HNRNPC
 heterogeneous nuclear ribonucleoprotein C (C1/C2)
 35
 0.97
chr1_10759853_10760004 0.56 CASZ1
 castor zinc finger 1
 54795
 0.12
chr1_60162288_60162439 0.56 ENSG00000266150
 .
 36605
 0.2
chr7_30634096_30634338 0.55 GARS
 glycyl-tRNA synthetase
 80
 0.61
chrX_70917395_70917655 0.55 ENSG00000221684
 .
 61780
 0.11
chr6_144732729_144732880 0.55 UTRN
 utrophin
 67567
 0.13
chr1_26872331_26872899 0.55 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
 272
 0.88
chr13_28715875_28716136 0.55 PAN3
 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
 2835
 0.24
chr4_156760399_156760658 0.55 TDO2
 tryptophan 2,3-dioxygenase
 15386
 0.21
chr17_47287660_47288689 0.54 GNGT2
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
 238
 0.65
chr1_154915200_154915451 0.54 PMVK
 phosphomevalonate kinase
 5858
 0.09
chrX_106362200_106362401 0.53 RBM41
 RNA binding motif protein 41
 243
 0.94
chr8_97533683_97533834 0.53 SDC2
 syndecan 2
 27522
 0.23
chr7_154719533_154719892 0.53 PAXIP1-AS2
 PAXIP1 antisense RNA 2
 515
 0.78
chr15_89009981_89010294 0.53 MRPL46
 mitochondrial ribosomal protein L46
 513
 0.47
chr17_19280691_19280938 0.53 MAPK7
 mitogen-activated protein kinase 7
 220
 0.65
chr7_155437664_155437928 0.52 RBM33
 RNA binding motif protein 33
 400
 0.67
chr7_64541108_64541627 0.52 ENSG00000207062
 .
 10451
 0.15
chr13_99226843_99226994 0.51 STK24
 serine/threonine kinase 24
 2199
 0.3
chr11_116644068_116644415 0.51 AP006216.10
136
 0.83
chr19_16379423_16379574 0.51 CTD-2562J15.6
24888
 0.13
chr3_185652121_185652403 0.51 TRA2B
 transformer 2 beta homolog (Drosophila)
 3539
 0.25
chr18_60984919_60985484 0.51 BCL2
 B-cell CLL/lymphoma 2
 844
 0.57
chrX_71003427_71003880 0.50 ENSG00000221684
 .
 24348
 0.23
chr20_30262987_30263252 0.50 RP11-243J16.7
10900
 0.13
chr11_8929144_8929295 0.50 ST5
 suppression of tumorigenicity 5
 3279
 0.14
chr12_111867666_111868155 0.49 SH2B3
 SH2B adaptor protein 3
 4756
 0.21
chr4_103423579_103423896 0.49 NFKB1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
 682
 0.61
chrY_15017679_15018174 0.49 DDX3Y
 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
 277
 0.95
chr11_65647291_65647461 0.48 CTSW
 cathepsin W
 47
 0.93
chr7_128379466_128379711 0.48 CALU
 calumenin
 130
 0.94
chrX_111125134_111125285 0.48 TRPC5OS
 TRPC5 opposite strand
 84
 0.98
chr12_1920714_1920865 0.48 CACNA2D4
 calcium channel, voltage-dependent, alpha 2/delta subunit 4
 97
 0.97
chr11_67204819_67205147 0.48 PTPRCAP
 protein tyrosine phosphatase, receptor type, C-associated protein
 555
 0.47
chr19_50879744_50879984 0.48 NR1H2
 nuclear receptor subfamily 1, group H, member 2
 134
 0.91
chr8_26162809_26162960 0.47 PPP2R2A
 protein phosphatase 2, regulatory subunit B, alpha
 11885
 0.26
chr2_106407332_106407557 0.47 NCK2
 NCK adaptor protein 2
 25571
 0.24
chr1_8685789_8685940 0.47 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 1425
 0.54
chr13_50158821_50159403 0.47 RCBTB1
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
 602
 0.77
chr2_85076559_85076967 0.47 TRABD2A
 TraB domain containing 2A
 31443
 0.16
chr11_67186882_67187131 0.47 PPP1CA
 protein phosphatase 1, catalytic subunit, alpha isozyme
 1646
 0.15
chr1_100715442_100715812 0.47 DBT
 dihydrolipoamide branched chain transacylase E2
 237
 0.9
chr21_36418295_36418575 0.47 RUNX1
 runt-related transcription factor 1
 3027
 0.41
chr21_34142699_34142850 0.47 PAXBP1
 PAX3 and PAX7 binding protein 1
 1205
 0.34
chr19_12847748_12847986 0.47 ASNA1
 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
 86
 0.91
chr10_64134972_64135123 0.46 ZNF365
 zinc finger protein 365
 256
 0.94
chr19_12906733_12906884 0.46 CTD-2659N19.10
829
 0.32
chr1_50513511_50513662 0.46 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
 100
 0.97
chr3_16926768_16927235 0.46 PLCL2
 phospholipase C-like 2
 549
 0.84
chr18_9404902_9405053 0.46 RALBP1
 ralA binding protein 1
 70030
 0.08
chr20_61554036_61554389 0.45 DIDO1
 death inducer-obliterator 1
 3609
 0.18
chr3_129034345_129034731 0.45 H1FX-AS1
 H1FX antisense RNA 1
 175
 0.82
chrX_70838155_70838405 0.45 CXCR3
 chemokine (C-X-C motif) receptor 3
 80
 0.97
chr1_168523425_168523576 0.45 XCL2
 chemokine (C motif) ligand 2
 10265
 0.23
chr6_150038866_150039094 0.45 LATS1
 large tumor suppressor kinase 1
 190
 0.93
chr9_20622216_20622410 0.45 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
 201
 0.95
chr3_172232547_172232820 0.44 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
 8582
 0.25
chr4_151995452_151995603 0.44 RPS3A
 ribosomal protein S3A
 25198
 0.14
chr10_5855917_5856253 0.44 GDI2
 GDP dissociation inhibitor 2
 207
 0.94
chr2_87214834_87214999 0.43 PLGLB1
 plasminogen-like B1
 34059
 0.19
chr4_6576981_6577196 0.43 MAN2B2
 mannosidase, alpha, class 2B, member 2
 146
 0.96
chr19_58898981_58899504 0.43 RPS5
 ribosomal protein S5
 586
 0.41
chr15_93457570_93457977 0.43 CHD2
 chromodomain helicase DNA binding protein 2
 10070
 0.2
chr14_22972748_22972969 0.43 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 16687
 0.09
chr2_88081579_88081730 0.42 PLGLB2
 plasminogen-like B2
 34048
 0.19
chr11_17298295_17298504 0.42 NUCB2
 nucleobindin 2
 21
 0.98
chr17_60802287_60802509 0.42 MARCH10
 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
 11480
 0.17
chr13_113807206_113807543 0.42 PROZ
 protein Z, vitamin K-dependent plasma glycoprotein
 5594
 0.13
chr7_26192485_26193339 0.42 NFE2L3
 nuclear factor, erythroid 2-like 3
 1052
 0.53
chr6_159420910_159421511 0.42 RSPH3
 radial spoke 3 homolog (Chlamydomonas)
 9
 0.82
chr7_99096274_99096688 0.42 ZNF394
 zinc finger protein 394
 1406
 0.25
chr12_55373639_55373790 0.42 TESPA1
 thymocyte expressed, positive selection associated 1
 1908
 0.39
chr11_111798023_111798431 0.42 DIXDC1
 DIX domain containing 1
 359
 0.67
chr16_2015079_2015314 0.42 ENSG00000255198
 .
 11
 0.78
chr1_226068030_226068371 0.42 TMEM63A
 transmembrane protein 63A
 1869
 0.24
chr12_4938445_4938596 0.41 RP3-377H17.2
9601
 0.2
chr4_38666789_38667086 0.41 RP11-617D20.1
433
 0.48
chr2_110595491_110595642 0.41 RGPD5
 RANBP2-like and GRIP domain containing 5
 43304
 0.17
chr14_64107873_64108536 0.41 WDR89
 WD repeat domain 89
 79
 0.96
chr2_108489338_108489489 0.41 RGPD4
 RANBP2-like and GRIP domain containing 4
 46020
 0.19
chr19_48835680_48835937 0.41 EMP3
 epithelial membrane protein 3
 6943
 0.11
chr9_80523811_80523962 0.41 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 85971
 0.1
chr17_38559088_38559385 0.41 ENSG00000222881
 .
 11646
 0.11
chr11_124618587_124618738 0.41 RP11-677M14.2
2429
 0.15
chr19_50651113_50651549 0.41 IZUMO2
 IZUMO family member 2
 15082
 0.15
chr6_11382632_11382872 0.40 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 171
 0.97
chr3_39321282_39321554 0.40 CX3CR1
 chemokine (C-X3-C motif) receptor 1
 107
 0.97
chr12_14518062_14518320 0.40 ATF7IP
 activating transcription factor 7 interacting protein
 425
 0.88
chr8_22463688_22463839 0.40 CCAR2
 cell cycle and apoptosis regulator 2
 350
 0.76
chr10_106027925_106028215 0.40 ENSG00000266852
 .
 107
 0.87
chr2_169458843_169458994 0.40 ENSG00000199348
 .
 4088
 0.27
chr2_113145556_113145707 0.40 RGPD8
 RANBP2-like and GRIP domain containing 8
 45465
 0.15
chr1_198637715_198637866 0.39 RP11-553K8.5
1600
 0.47
chr12_54811406_54811839 0.39 ITGA5
 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
 1622
 0.22
chr6_26442341_26442492 0.39 BTN3A3
 butyrophilin, subfamily 3, member A3
 1630
 0.25
chr15_68570739_68571112 0.39 FEM1B
 fem-1 homolog b (C. elegans)
 784
 0.64
chr1_43803771_43803922 0.39 MPL
 myeloproliferative leukemia virus oncogene
 326
 0.8
chr1_21859764_21859915 0.39 ALPL
 alkaline phosphatase, liver/bone/kidney
 17933
 0.19
chr6_29692032_29692183 0.39 HLA-F
 major histocompatibility complex, class I, F
 291
 0.87
chr2_111291029_111291180 0.39 RGPD6
 RANBP2-like and GRIP domain containing 6
 483
 0.83
chr9_127950035_127950361 0.39 PPP6C
 protein phosphatase 6, catalytic subunit
 1864
 0.3
chr16_80838686_80839030 0.39 CDYL2
 chromodomain protein, Y-like 2
 632
 0.79
chr21_30397725_30398151 0.39 RP1-100J12.1
727
 0.42
chr5_134181747_134182027 0.38 C5orf24
 chromosome 5 open reading frame 24
 43
 0.97
chr20_13764930_13765215 0.38 ESF1
 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
 460
 0.52
chr5_154137578_154138162 0.38 LARP1
 La ribonucleoprotein domain family, member 1
 1136
 0.49
chr1_152162233_152162399 0.38 FLG-AS1
 FLG antisense RNA 1
 489
 0.77
chr6_134861028_134861179 0.38 SGK1
 serum/glucocorticoid regulated kinase 1
 221853
 0.02
chr2_28616306_28616795 0.37 FOSL2
 FOS-like antigen 2
 825
 0.43
chr22_50523508_50523892 0.37 MLC1
 megalencephalic leukoencephalopathy with subcortical cysts 1
 12
 0.97
chr11_559952_560103 0.37 RASSF7
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
 377
 0.43
chr3_141121878_141122254 0.37 ZBTB38
 zinc finger and BTB domain containing 38
 406
 0.88
chr2_106367063_106367214 0.37 NCK2
 NCK adaptor protein 2
 4950
 0.33
chr3_160167041_160167544 0.37 TRIM59
 tripartite motif containing 59
 109
 0.96
chr16_8715324_8715502 0.37 METTL22
 methyltransferase like 22
 127
 0.97
chr19_47125438_47125589 0.37 PTGIR
 prostaglandin I2 (prostacyclin) receptor (IP)
 2781
 0.13
chr10_43902220_43902565 0.37 HNRNPF
 heterogeneous nuclear ribonucleoprotein F
 875
 0.54
chr9_134405336_134405487 0.37 UCK1
 uridine-cytidine kinase 1
 1155
 0.4
chr11_67176589_67176876 0.37 TBC1D10C
 TBC1 domain family, member 10C
 5072
 0.07
chr2_231191950_231192650 0.36 SP140L
 SP140 nuclear body protein-like
 315
 0.92
chr1_170536747_170536898 0.36 RP11-576I22.2
35034
 0.18
chr16_3660969_3661192 0.36 SLX4
 SLX4 structure-specific endonuclease subunit
 519
 0.73
chr19_10675577_10675931 0.36 KRI1
 KRI1 homolog (S. cerevisiae)
 912
 0.35
chr1_212588032_212588228 0.35 TMEM206
 transmembrane protein 206
 107
 0.96
chr2_118572851_118573368 0.35 DDX18
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
 883
 0.63
chr2_98261858_98262243 0.35 COX5B
 cytochrome c oxidase subunit Vb
 453
 0.77
chr9_130692852_130693086 0.35 PIP5KL1
 phosphatidylinositol-4-phosphate 5-kinase-like 1
 107
 0.92
chr2_204735521_204735672 0.35 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 641
 0.79
chr3_71630406_71630763 0.35 FOXP1
 forkhead box P1
 2320
 0.31
chr1_59164702_59165010 0.35 MYSM1
 Myb-like, SWIRM and MPN domains 1
 908
 0.62
chr12_66524690_66525029 0.35 LLPH
 LLP homolog, long-term synaptic facilitation (Aplysia)
 311
 0.49
chr1_32721190_32721341 0.35 LCK
 lymphocyte-specific protein tyrosine kinase
 4390
 0.1
chr9_130536234_130536385 0.35 SH2D3C
 SH2 domain containing 3C
 2592
 0.13
chr4_4290910_4291202 0.35 LYAR
 Ly1 antibody reactive
 692
 0.48

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF784

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.4 1.3 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.4 1.1 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2 0.7 GO:0008049 male courtship behavior(GO:0008049)
0.2 0.6 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.2 0.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.0 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.4 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.3 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.1 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.4 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.2 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.3 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.1 0.5 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.2 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.1 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 1.4 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.1 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.2 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.4 GO:1904377 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.3 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.6 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.2 GO:0021554 optic nerve development(GO:0021554)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.5 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.3 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.1 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 1.0 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.0 0.2 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:1901021 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.4 GO:0009268 response to pH(GO:0009268)
0.0 0.2 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.5 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.1 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.2 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.3 GO:1902579 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.2 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.5 GO:0007602 phototransduction(GO:0007602)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.0 GO:0010823 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.3 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.6 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.0 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.7 GO:0072431 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.0 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.0 GO:0003417 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 0.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 1.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.2 GO:0008542 visual learning(GO:0008542)
0.0 0.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.2 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.5 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.6 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.1 GO:1903578 regulation of glycolytic process(GO:0006110) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0000800 lateral element(GO:0000800)
0.1 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0045120 pronucleus(GO:0045120)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.5 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 2.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:1990391 mismatch repair complex(GO:0032300) DNA repair complex(GO:1990391)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.0 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.0 GO:0005840 ribosome(GO:0005840)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 1.2 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034711 inhibin binding(GO:0034711)
0.2 2.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0032356 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.1 0.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0051400 BH domain binding(GO:0051400)
0.1 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.3 GO:0001846 opsonin binding(GO:0001846)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 1.2 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.5 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.4 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.0 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 1.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1