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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Atf6

Z-value: 0.67

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Transcription factors associated with Atf6

Gene Symbol	Gene ID	Gene Info
Atf6 Ensembl NCBI MGI UniProt	ENSMUSG00000026663.6	activating transcription factor 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_170865952_170866401	Atf6	1595	0.218736	0.29	2.7e-02	Click!
chr1_170850781_170851108	Atf6	16827	0.100430	0.21	1.0e-01	Click!
chr1_170862007_170862469	Atf6	5533	0.112590	0.20	1.2e-01	Click!
chr1_170862585_170862871	Atf6	5043	0.114833	0.14	2.9e-01	Click!
chr1_170855175_170855341	Atf6	12513	0.103036	0.11	4.1e-01	Click!

Activity of the Atf6 motif across conditions

Conditions sorted by the z-value of the Atf6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_19645245_19645748	1.90	Trim55	tripartite motif-containing 55	988	0.49
chr2_114051146_114052179	1.90	Actc1	actin, alpha, cardiac muscle 1	1225	0.4
chr7_128205575_128206445	1.55	Cox6a2	cytochrome c oxidase subunit 6A2	377	0.67
chr5_13388919_13389128	1.34	Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	7761	0.27
chr15_95883480_95883763	1.28	Gm25070	predicted gene, 25070	3804	0.23
chr15_51671776_51672466	1.23	Gm34562	predicted gene, 34562	42486	0.18
chr5_76858347_76858498	1.15	C530008M17Rik	RIKEN cDNA C530008M17 gene	420	0.83
chr1_176836732_176837286	0.98	Gm38158	predicted gene, 38158	1285	0.31
chr14_79535326_79536502	0.94	Elf1	E74-like factor 1	20216	0.14
chr17_80933683_80933890	0.92	Gm9386	predicted pseudogene 9386	4928	0.22
chr15_102998770_103001153	0.90	Hoxc6	homeobox C6	568	0.54
chr2_173026008_173027110	0.89	Rbm38	RNA binding motif protein 38	3509	0.16
chr13_73260273_73261531	0.87	Irx4	Iroquois homeobox 4	405	0.82
chr17_88626308_88627392	0.87	Ston1	stonin 1	17	0.97
chr5_67814487_67814851	0.84	Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	561	0.69
chr11_85644044_85644852	0.81	Bcas3	breast carcinoma amplified sequence 3	3744	0.28
chr1_135132701_135133163	0.81	Ptpn7	protein tyrosine phosphatase, non-receptor type 7	207	0.62
chrX_20869884_20870823	0.80	Timp1	tissue inhibitor of metalloproteinase 1	132	0.93
chr3_126638700_126639237	0.80	Gm43009	predicted gene 43009	5493	0.13
chr6_72389419_72390767	0.79	Vamp8	vesicle-associated membrane protein 8	182	0.89
chr2_91964507_91965860	0.79	Dgkz	diacylglycerol kinase zeta	404	0.78
chr2_147364921_147366397	0.78	Pax1	paired box 1	665	0.65
chr2_58971390_58971583	0.74	Gm13557	predicted gene 13557	11779	0.23
chr2_61134857_61135072	0.72	Gm13581	predicted gene 13581	89828	0.08
chr7_4520460_4522358	0.72	Tnni3	troponin I, cardiac 3	842	0.35
chr4_134370560_134370711	0.72	Extl1	exostosin-like glycosyltransferase 1	1923	0.22
chr5_67685052_67685241	0.72	Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	25112	0.13
chr18_84739596_84739757	0.71	Gm25005	predicted gene, 25005	2641	0.17
chr3_90450566_90451614	0.71	Gm16048	predicted gene 16048	493	0.47
chr10_63366309_63366946	0.71	Gm16145	predicted gene 16145	12774	0.12
chr16_55820581_55820972	0.70	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta	1362	0.42
chr16_35223934_35224723	0.70	Gm25179	predicted gene, 25179	10595	0.2
chr18_82742660_82742818	0.70	Gm50355	predicted gene, 50355	12758	0.09
chr9_48648789_48650102	0.69	Nnmt	nicotinamide N-methyltransferase	44292	0.16
chr1_74090075_74091356	0.68	Tns1	tensin 1	636	0.71
chr10_79777651_79778485	0.68	Fstl3	follistatin-like 3	776	0.36
chr8_91800429_91802211	0.67	Irx3	Iroquois related homeobox 3	595	0.52
chr7_78913499_78914279	0.67	Isg20	interferon-stimulated protein	92	0.95
chr2_32317910_32318744	0.67	Gm23363	predicted gene, 23363	62	0.57
chr10_125948870_125949497	0.66	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	16985	0.28
chr7_48881832_48882357	0.66	E2f8	E2F transcription factor 8	498	0.56
chr1_162217585_162219370	0.65	Dnm3os	dynamin 3, opposite strand	601	0.46
chr6_119192581_119192732	0.65	Dcp1b	decapping mRNA 1B	300	0.9
chr8_92359084_92360805	0.64	Irx5	Iroquois homeobox 5	2195	0.28
chr5_72493846_72493997	0.63	AU023070	expressed sequence AU023070	3183	0.18
chr3_69438903_69439406	0.62	Gm17213	predicted gene 17213	6786	0.23
chr5_51567511_51568201	0.62	Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	130	0.97
chr11_115413080_115413482	0.62	Mrpl58	mitochondrial ribosomal protein L58	3121	0.1
chr14_54993776_54993927	0.61	Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	160	0.86
chr10_127520798_127521520	0.61	Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	1205	0.29
chr8_61359671_61360071	0.61	Sh3rf1	SH3 domain containing ring finger 1	1718	0.33
chr4_133871871_133872343	0.61	Rps6ka1	ribosomal protein S6 kinase polypeptide 1	206	0.57
chr17_7825546_7825832	0.61	Fndc1	fibronectin type III domain containing 1	1613	0.46
chr14_69544240_69544830	0.61	Gm27174	predicted gene 27174	10797	0.1
chr8_111509286_111509760	0.61	Wdr59	WD repeat domain 59	12464	0.17
chr14_69325989_69326578	0.60	Gm16677	predicted gene, 16677	10799	0.1
chr15_7081297_7081448	0.60	Lifr	LIF receptor alpha	9242	0.28
chr8_84197222_84198671	0.60	Gm26887	predicted gene, 26887	279	0.72
chr16_74900702_74901266	0.59	Gm49674	predicted gene, 49674	25046	0.23
chr8_60978610_60978873	0.59	Clcn3	chloride channel, voltage-sensitive 3	4498	0.16
chr16_82078464_82078615	0.59	Gm41480	predicted gene, 41480	93752	0.09
chr6_55336550_55338274	0.59	Aqp1	aquaporin 1	980	0.5
chr9_90238245_90238501	0.59	Gm16200	predicted gene 16200	16748	0.15
chr1_36535151_36535302	0.58	Ankrd23	ankyrin repeat domain 23	513	0.58
chr5_101295911_101296062	0.58	Cycs-ps2	cytochrome c, pseudogene 2	9592	0.3
chr14_75773006_75773655	0.58	Slc25a30	solute carrier family 25, member 30	1002	0.48
chr14_74899774_74900395	0.58	Lrch1	leucine-rich repeats and calponin homology (CH) domain containing 1	362	0.89
chr9_58156326_58158409	0.58	Islr	immunoglobulin superfamily containing leucine-rich repeat	1178	0.35
chr11_117810668_117810903	0.57	Syngr2	synaptogyrin 2	1073	0.23
chr9_21495923_21496771	0.56	Mir199a-1	microRNA 199a-1	217	0.87
chr5_118716392_118716543	0.56	Gm43051	predicted gene 43051	9065	0.18
chr10_95560034_95560711	0.56	Mir3058	microRNA 3058	1051	0.41
chr7_128523279_128524917	0.56	Bag3	BCL2-associated athanogene 3	482	0.7
chr11_78176699_78177813	0.55	Tlcd1	TLC domain containing 1	545	0.32
chr6_30275473_30275686	0.55	Ube2h	ubiquitin-conjugating enzyme E2H	28943	0.13
chr16_87661046_87661653	0.55	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	37596	0.14
chr4_47603509_47604277	0.54	Sec61b	Sec61 beta subunit	128945	0.05
chr10_126249067_126249277	0.54	1700021G15Rik	RIKEN cDNA 1700021G15 gene	5945	0.28
chr19_40812757_40814183	0.54	Ccnj	cyclin J	17809	0.16
chr18_65086028_65086226	0.54	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	3073	0.32
chr18_16436164_16436577	0.54	Gm7665	predicted pseudogene 7665	161426	0.04
chr2_9906124_9906915	0.53	Gm13262	predicted gene 13262	341	0.81
chr6_29433018_29434456	0.53	Flnc	filamin C, gamma	461	0.68
chr9_44509311_44510671	0.53	Bcl9l	B cell CLL/lymphoma 9-like	10719	0.07
chr4_135269698_135270041	0.53	Clic4	chloride intracellular channel 4 (mitochondrial)	2945	0.19
chr9_72790995_72791235	0.53	Gm27204	predicted gene 27204	14890	0.11
chr10_116907989_116908576	0.53	Myrfl	myelin regulatory factor-like	11363	0.14
chr15_41819857_41820760	0.52	Oxr1	oxidation resistance 1	10624	0.21
chr3_94372701_94373986	0.52	Rorc	RAR-related orphan receptor gamma	549	0.5
chr7_19755645_19756922	0.52	Bcam	basal cell adhesion molecule	668	0.44
chr15_79891602_79892946	0.52	Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	129	0.93
chr12_101815999_101816150	0.51	Fbln5	fibulin 5	2394	0.3
chr9_78109229_78109591	0.51	Cilk1	ciliogenesis associated kinase 1	175	0.69
chr5_64969599_64970792	0.51	Mir574	microRNA 574	123	0.49
chr6_88914852_88915003	0.51	Tpra1	transmembrane protein, adipocyte asscociated 1	4328	0.13
chr2_28619027_28619457	0.51	Gfi1b	growth factor independent 1B	2703	0.16
chr7_28895190_28896201	0.50	Actn4	actinin alpha 4	843	0.4
chr1_183043326_183043599	0.50	Gm24975	predicted gene, 24975	31144	0.17
chr6_100707791_100708009	0.50	Gxylt2	glucoside xylosyltransferase 2	3145	0.21
chr12_36042503_36042830	0.49	Tspan13	tetraspanin 13	166	0.95
chr19_8966323_8966828	0.49	Eef1g	eukaryotic translation elongation factor 1 gamma	466	0.59
chr7_34969891_34970042	0.49	Pepd	peptidase D	456	0.79
chr14_27000422_27001594	0.49	Hesx1	homeobox gene expressed in ES cells	646	0.71
chr13_31557307_31557458	0.48	Foxq1	forkhead box Q1	1248	0.33
chr14_22650546_22651065	0.48	Lrmda	leucine rich melanocyte differentiation associated	54292	0.15
chr7_46098554_46099159	0.48	Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	430	0.7
chr16_38349264_38349423	0.48	Cox17	cytochrome c oxidase assembly protein 17, copper chaperone	51	0.95
chr5_92126937_92127088	0.48	Gm24931	predicted gene, 24931	8729	0.12
chr16_11132883_11133177	0.48	Txndc11	thioredoxin domain containing 11	1523	0.24
chr8_127499743_127499894	0.48	Pard3	par-3 family cell polarity regulator	52072	0.15
chr10_97569634_97569998	0.47	Lum	lumican	4688	0.2
chr5_34513269_34513607	0.47	Tnip2	TNFAIP3 interacting protein 2	222	0.87
chr4_139213834_139214196	0.47	Capzb	capping protein (actin filament) muscle Z-line, beta	12946	0.15
chr18_6765962_6766182	0.46	Rab18	RAB18, member RAS oncogene family	852	0.59
chr1_157506653_157507518	0.46	Sec16b	SEC16 homolog B (S. cerevisiae)	275	0.89
chr7_16049633_16049784	0.46	Bicra	BRD4 interacting chromatin remodeling complex associated protein	1787	0.26
chr4_83988157_83988444	0.46	6030471H07Rik	RIKEN cDNA 6030471H07 gene	56579	0.14
chr16_30502280_30503028	0.46	Tmem44	transmembrane protein 44	38255	0.14
chr18_3337426_3337723	0.46	Crem	cAMP responsive element modulator	0	0.95
chr10_40069416_40069623	0.45	Slc16a10	solute carrier family 16 (monocarboxylic acid transporters), member 10	7086	0.15
chr1_58970537_58971332	0.45	Trak2	trafficking protein, kinesin binding 2	2495	0.2
chr11_98942977_98944518	0.45	Gm22061	predicted gene, 22061	2697	0.15
chr19_17715311_17715754	0.45	Gm17819	predicted gene, 17819	22769	0.24
chr4_144892505_144894616	0.45	Dhrs3	dehydrogenase/reductase (SDR family) member 3	341	0.9
chr3_135843805_135844446	0.45	4933401H06Rik	RIKEN cDNA 4933401H06 gene	3856	0.17
chr13_53293118_53293480	0.45	Ror2	receptor tyrosine kinase-like orphan receptor 2	7175	0.26
chr3_61007230_61007427	0.45	Gm37035	predicted gene, 37035	3542	0.26
chr16_35856692_35857450	0.45	Gm49730	predicted gene, 49730	10880	0.11
chr4_43399011_43400247	0.45	Rusc2	RUN and SH3 domain containing 2	1609	0.28
chr16_10351123_10351731	0.44	Gm1600	predicted gene 1600	3836	0.19
chr5_107055692_107055907	0.44	Gm33474	predicted gene, 33474	6963	0.21
chr2_43727917_43728150	0.44	Arhgap15	Rho GTPase activating protein 15	20791	0.25
chr3_51647992_51648578	0.44	Gm38247	predicted gene, 38247	11357	0.12
chr4_154926952_154928851	0.43	Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	176	0.92
chr13_41345830_41346374	0.43	Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	13145	0.14
chr14_62839032_62839183	0.43	Mir8098	microRNA 8098	1386	0.26
chr6_29145493_29146283	0.43	Gm24303	predicted gene, 24303	4791	0.15
chr11_116108498_116109194	0.43	Trim47	tripartite motif-containing 47	727	0.48
chr14_74883096_74883506	0.43	Lrch1	leucine-rich repeats and calponin homology (CH) domain containing 1	1954	0.38
chr13_46523768_46523919	0.43	Gm24915	predicted gene, 24915	5159	0.2
chr7_82972123_82972274	0.42	Gm6112	predicted gene 6112	4981	0.19
chr3_120154232_120154383	0.42	Gm23733	predicted gene, 23733	163682	0.04
chr2_148040523_148041116	0.42	9030622O22Rik	RIKEN cDNA 9030622O22 gene	616	0.69
chr15_77754021_77754265	0.42	Apol8	apolipoprotein L 8	1096	0.34
chr6_91212520_91213912	0.42	Fbln2	fibulin 2	385	0.81
chr16_33833704_33834426	0.42	Itgb5	integrin beta 5	4388	0.19
chr4_102573848_102574668	0.41	Pde4b	phosphodiesterase 4B, cAMP specific	4163	0.35
chr13_54737787_54738662	0.41	Gprin1	G protein-regulated inducer of neurite outgrowth 1	11445	0.12
chr10_96080755_96081083	0.41	Gm49817	predicted gene, 49817	15086	0.18
chr8_12883296_12883723	0.41	Gm15353	predicted gene 15353	207	0.89
chr10_8813926_8814547	0.41	Gm25410	predicted gene, 25410	9911	0.2
chr9_58618612_58618956	0.41	Nptn	neuroplastin	10321	0.19
chr17_29963564_29965159	0.41	Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	5726	0.14
chr3_96086685_96086928	0.41	Gm43554	predicted gene 43554	65	0.95
chr5_143509158_143510231	0.41	Rac1	Rac family small GTPase 1	7914	0.12
chr19_12787825_12787976	0.40	Zfp91	zinc finger protein 91	2409	0.18
chr9_24773249_24774873	0.40	Tbx20	T-box 20	223	0.92
chr4_88550254_88550926	0.40	Ifna15	interferon alpha 15	7655	0.1
chr8_71702224_71703093	0.40	B3gnt3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	869	0.35
chr6_5292547_5292698	0.40	Pon2	paraoxonase 2	3554	0.22
chr4_127311434_127313205	0.40	Gja4	gap junction protein, alpha 4	1720	0.26
chr19_46961982_46962292	0.40	Nt5c2	5'-nucleotidase, cytosolic II	171	0.95
chr4_156097797_156097948	0.40	9430015G10Rik	RIKEN cDNA 9430015G10 gene	12110	0.09
chr3_65863495_65863989	0.39	Gm37131	predicted gene, 37131	1087	0.47
chr14_114948177_114949378	0.39	Gm31072	predicted gene, 31072	2752	0.2
chr16_76899025_76899244	0.39	1700041M19Rik	RIKEN cDNA 1700041M19 gene	9853	0.22
chr5_120648567_120649750	0.39	Rasal1	RAS protein activator like 1 (GAP1 like)	30	0.93
chrX_53267645_53268215	0.39	Fam122b	family with sequence similarity 122, member B	1090	0.45
chr12_9578132_9580204	0.39	Osr1	odd-skipped related transcription factor 1	4727	0.2
chr1_162223270_162223824	0.38	Mir214	microRNA 214	179	0.94
chr9_104269391_104269542	0.37	Dnajc13	DnaJ heat shock protein family (Hsp40) member C13	6536	0.17
chr15_36793767_36794515	0.37	Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	304	0.87
chr4_10874610_10875403	0.37	2610301B20Rik	RIKEN cDNA 2610301B20 gene	438	0.65
chr11_109439895_109440542	0.37	Amz2	archaelysin family metallopeptidase 2	62	0.95
chr2_77518539_77519669	0.37	Zfp385b	zinc finger protein 385B	431	0.89
chrX_136737915_136738066	0.37	Morf4l2	mortality factor 4 like 2	2493	0.18
chr12_56612812_56613598	0.37	Nkx2-9	NK2 homeobox 9	79	0.95
chr17_25088413_25088890	0.37	Ift140	intraflagellar transport 140	2020	0.19
chr11_79071094_79071622	0.37	Ksr1	kinase suppressor of ras 1	3128	0.28
chr17_70848658_70849785	0.37	Tgif1	TGFB-induced factor homeobox 1	423	0.71
chr14_51007919_51008098	0.37	Rnase10	ribonuclease, RNase A family, 10 (non-active)	79	0.93
chr8_48511120_48511677	0.37	Tenm3	teneurin transmembrane protein 3	43915	0.19
chr13_68607500_68608505	0.37	1700001L19Rik	RIKEN cDNA 1700001L19 gene	10563	0.16
chr2_163390311_163390571	0.36	Jph2	junctophilin 2	7508	0.14
chr4_155734860_155735214	0.36	Tmem240	transmembrane protein 240	163	0.64
chr15_78672118_78673052	0.36	1700041B01Rik	RIKEN cDNA 1700041B01 gene	1800	0.25
chr8_46613596_46613811	0.35	Primpol	primase and polymerase (DNA-directed)	688	0.61
chr1_138460021_138460172	0.35	Gm28501	predicted gene 28501	55519	0.12
chr10_70120556_70121768	0.35	Ccdc6	coiled-coil domain containing 6	24041	0.22
chr12_73545329_73546631	0.35	Tmem30b	transmembrane protein 30B	412	0.8
chr5_103759804_103761265	0.35	Aff1	AF4/FMR2 family, member 1	5961	0.23
chr2_144160017_144160629	0.35	Gm5535	predicted gene 5535	14041	0.15
chr3_138064815_138065971	0.34	1110002E22Rik	RIKEN cDNA 1110002E22 gene	341	0.81
chr3_100438730_100438910	0.34	Gm43121	predicted gene 43121	986	0.48
chr9_43101838_43102807	0.34	Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	3164	0.24
chr3_51378444_51378901	0.34	Gm5103	predicted gene 5103	596	0.57
chr6_97311036_97312726	0.34	Frmd4b	FERM domain containing 4B	499	0.83
chr3_31094860_31095141	0.34	Skil	SKI-like	58	0.98
chr2_84733750_84735007	0.34	Ypel4	yippee like 4	151	0.89
chr13_63245084_63245617	0.34	Gm47586	predicted gene, 47586	1129	0.31

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2	0.6	GO:0036394	amylase secretion(GO:0036394)
0.2	0.6	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2	0.6	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.2	0.8	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.2	0.3	GO:0060460	left lung morphogenesis(GO:0060460)
0.2	0.8	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.1	0.4	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	0.5	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.1	0.4	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.1	0.4	GO:0021828	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1	0.5	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1	0.5	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.3	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.3	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.1	0.2	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	0.6	GO:0060017	parathyroid gland development(GO:0060017)
0.1	0.3	GO:0072162	metanephric mesenchymal cell differentiation(GO:0072162)
0.1	0.4	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.1	0.2	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1	0.3	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.1	0.2	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.2	GO:2000437	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1	0.4	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1	0.7	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.4	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	0.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1	0.6	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.1	GO:0002461	tolerance induction dependent upon immune response(GO:0002461)
0.1	0.3	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	0.2	GO:1902302	regulation of potassium ion export(GO:1902302)
0.1	0.2	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.1	0.7	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.1	0.3	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.3	GO:0018214	protein carboxylation(GO:0018214)
0.1	0.2	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.1	0.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.3	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
0.1	0.4	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:0033505	floor plate morphogenesis(GO:0033505)
0.1	0.3	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:0042628	mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.0	0.2	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.3	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.5	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.0	0.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.0	GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0	0.4	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:0051794	regulation of catagen(GO:0051794)
0.0	0.2	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.2	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0	0.8	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
0.0	0.4	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.2	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.5	GO:0010666	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.0	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.0	0.2	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.2	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.3	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0	0.2	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.1	GO:0003175	tricuspid valve development(GO:0003175)
0.0	0.1	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.2	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.1	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.1	GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.0	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.1	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.1	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.2	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.0	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.0	0.0	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.3	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.2	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.2	GO:0060022	hard palate development(GO:0060022)
0.0	0.7	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0	0.2	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.1	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0	0.2	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.2	GO:0019348	dolichol metabolic process(GO:0019348)
0.0	0.2	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.1	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0040031	snRNA modification(GO:0040031)
0.0	0.1	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.2	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.0	0.1	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:1904659	glucose transmembrane transport(GO:1904659)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.0	0.4	GO:0010664	negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0	0.2	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.1	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.0	0.3	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:0071236	cellular response to antibiotic(GO:0071236)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.3	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.0	GO:0097501	stress response to metal ion(GO:0097501)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.2	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:2000121	regulation of removal of superoxide radicals(GO:2000121)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0051256	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.0	GO:0097212	lysosomal membrane organization(GO:0097212)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.4	GO:0044247	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.1	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244)
0.0	0.0	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.1	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.0	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.0	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.2	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.3	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.0	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.0	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.0	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.0	0.5	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.0	GO:0045472	response to ether(GO:0045472)
0.0	0.1	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.3	GO:1903861	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0	0.1	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.0	0.1	GO:0060696	regulation of phospholipid catabolic process(GO:0060696)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.2	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.0	0.0	GO:1903867	chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533)
0.0	0.3	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.1	GO:0051126	negative regulation of actin nucleation(GO:0051126)
0.0	0.1	GO:0098597	vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.1	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.0	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.2	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.0	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.0	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.0	GO:0050904	diapedesis(GO:0050904)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.0	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
0.0	0.0	GO:0090194	negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0097369	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.0	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0	0.0	GO:0043379	memory T cell differentiation(GO:0043379)
0.0	0.0	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.0	0.0	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0	0.1	GO:0014029	neural crest formation(GO:0014029)
0.0	0.2	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.0	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.2	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.4	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.1	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.2	GO:0046688	response to copper ion(GO:0046688)
0.0	0.0	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.2	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.8	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0061032	visceral serous pericardium development(GO:0061032)
0.0	0.0	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.0	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0060618	nipple development(GO:0060618)
0.0	0.2	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.5	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.0	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.5	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.2	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0030149	sphingolipid catabolic process(GO:0030149) ceramide catabolic process(GO:0046514)
0.0	0.1	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.0	0.1	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.1	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.0	GO:0003180	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.0	0.0	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.1	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.3	GO:0006414	translational elongation(GO:0006414)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0046078	dUMP metabolic process(GO:0046078)
0.0	0.0	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.0	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.1	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.3	GO:0032127	dense core granule membrane(GO:0032127)
0.1	0.3	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.1	0.7	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.2	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	0.2	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.2	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.3	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.2	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0071953	elastic fiber(GO:0071953)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.7	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.3	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.0	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.7	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.3	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0098651	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	1.8	GO:0031674	I band(GO:0031674)
0.0	0.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.1	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.0	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.0	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.2	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.0	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0097542	ciliary tip(GO:0097542)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	1.0	GO:0005604	basement membrane(GO:0005604)
0.0	0.0	GO:0005915	zonula adherens(GO:0005915)
0.0	0.3	GO:0014704	intercalated disc(GO:0014704)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0001650	fibrillar center(GO:0001650)
0.0	0.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.0	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	0.5	GO:0034548	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1	0.4	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.6	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.3	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.4	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.3	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.3	GO:0030172	troponin C binding(GO:0030172)
0.1	0.3	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	0.7	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.3	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1	0.9	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.2	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.2	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.1	0.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	1.1	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.1	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1	0.2	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.4	GO:0031432	titin binding(GO:0031432)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.6	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.3	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.2	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.3	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.8	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.3	GO:0033677	DNA/RNA helicase activity(GO:0033677)
0.0	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0000182	rDNA binding(GO:0000182)
0.0	0.2	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.3	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.4	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0	0.4	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.3	GO:0044466	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.0	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.7	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.2	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.6	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:1901611	phosphatidylglycerol binding(GO:1901611)
0.0	0.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.4	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.0	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.0	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.0	0.1	GO:0043733	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.0	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.5	GO:0005507	copper ion binding(GO:0005507)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.0	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0031386	protein tag(GO:0031386)
0.0	0.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.5	GO:0046332	SMAD binding(GO:0046332)
0.0	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.7	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.5	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.9	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.4	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.1	0.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.1	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling

Results for Atf6

Z-value: 0.67

Motif logo

Transcription factors associated with Atf6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Atf6 motif across conditions

Conditions sorted by the z-value of the Atf6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: