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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Batf3

Z-value: 0.50

Motif logo

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Transcription factors associated with Batf3

Gene Symbol Gene ID Gene Info
Batf3
ENSMUSG00000026630.4 basic leucine zipper transcription factor, ATF-like 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_191097653_191098840Batf3790.950610-0.364.8e-03Click!
chr1_191097128_191097279Batf36440.578474-0.152.7e-01Click!
chr1_191111232_191111383Batf3108300.113981-0.123.7e-01Click!

Activity of the Batf3 motif across conditions

Conditions sorted by the z-value of the Batf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_116572624_116573264 1.74 Ube2o
 ubiquitin-conjugating enzyme E2O
 8503
 0.1
chr4_142017816_142018715 1.69 4930455G09Rik
 RIKEN cDNA 4930455G09 gene
 367
 0.8
chr4_46040988_46042013 1.45 Tmod1
 tropomodulin 1
 2291
 0.3
chr17_34998907_34999597 1.43 Vars
 valyl-tRNA synthetase
 1735
 0.11
chr19_5686209_5687218 1.42 Pcnx3
 pecanex homolog 3
 1436
 0.16
chr6_57822563_57823744 1.38 Vopp1
 vesicular, overexpressed in cancer, prosurvival protein 1
 1487
 0.3
chr6_31651754_31651924 1.35 Gm43154
 predicted gene 43154
 797
 0.64
chr15_58575323_58575591 1.29 Fer1l6
 fer-1-like 6 (C. elegans)
 63048
 0.12
chr15_27871217_27871844 1.26 Gm20555
 predicted gene, 20555
 4299
 0.22
chr8_60953813_60955404 1.20 Clcn3
 chloride channel, voltage-sensitive 3
 140
 0.95
chr7_128414548_128415092 1.07 Gm15503
 predicted gene 15503
 2479
 0.18
chr17_53596477_53596632 1.05 Gm6919
 predicted gene 6919
 2109
 0.26
chr8_122306253_122307213 0.93 Zfpm1
 zinc finger protein, multitype 1
 587
 0.68
chr7_141146140_141146436 0.90 Ptdss2
 phosphatidylserine synthase 2
 8335
 0.08
chr3_127468377_127468752 0.88 Gm44494
 predicted gene, 44494
 12556
 0.1
chr8_70500810_70501374 0.87 Crlf1
 cytokine receptor-like factor 1
 41
 0.94
chr6_86472299_86472450 0.86 C87436
 expressed sequence C87436
 8334
 0.08
chr4_155893812_155895517 0.83 Acap3
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
 2352
 0.11
chr16_92340779_92341614 0.83 Smim34
 small integral membrane protein 34
 11942
 0.11
chr2_49730442_49730664 0.83 Kif5c
 kinesin family member 5C
 2058
 0.38
chr17_28013120_28014046 0.79 Anks1
 ankyrin repeat and SAM domain containing 1
 6238
 0.13
chr11_115511512_115512231 0.77 Jpt1
 Jupiter microtubule associated homolog 1
 2245
 0.14
chr7_142088584_142090929 0.77 Dusp8
 dual specificity phosphatase 8
 5516
 0.09
chr1_75214392_75214921 0.74 Stk16
 serine/threonine kinase 16
 1595
 0.14
chr10_80140825_80141682 0.72 Atp5d
 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
 204
 0.67
chr13_21935384_21936058 0.71 Zfp184
 zinc finger protein 184 (Kruppel-like)
 9373
 0.06
chr12_109543555_109544268 0.71 Meg3
 maternally expressed 3
 587
 0.28
chr2_129227304_129227665 0.69 A730036I17Rik
 RIKEN cDNA A730036I17 gene
 538
 0.53
chr7_97749255_97749938 0.67 Aqp11
 aquaporin 11
 11307
 0.16
chr2_29872842_29873027 0.67 2600006K01Rik
 RIKEN cDNA 2600006K01 gene
 2617
 0.14
chr13_55426059_55426382 0.64 F12
 coagulation factor XII (Hageman factor)
 559
 0.57
chr6_90466371_90466910 0.63 Klf15
 Kruppel-like factor 15
 240
 0.86
chr7_28982862_28983600 0.63 Map4k1
 mitogen-activated protein kinase kinase kinase kinase 1
 370
 0.72
chr14_87140347_87141190 0.62 Diaph3
 diaphanous related formin 3
 375
 0.89
chr15_78509793_78510375 0.59 Il2rb
 interleukin 2 receptor, beta chain
 14813
 0.09
chr11_33039362_33039684 0.59 Rpsa-ps4
 ribosomal protein S4, pseudogene 4
 180
 0.95
chr16_32671532_32671962 0.58 Tnk2
 tyrosine kinase, non-receptor, 2
 1407
 0.33
chr13_54687874_54688432 0.58 Rnf44
 ring finger protein 44
 35
 0.96
chr6_124463804_124465512 0.58 Clstn3
 calsyntenin 3
 136
 0.92
chr7_19022230_19023942 0.57 Foxa3
 forkhead box A3
 452
 0.57
chr2_105673131_105674553 0.55 Pax6
 paired box 6
 121
 0.95
chr2_30929161_30930147 0.54 Ptges
 prostaglandin E synthase
 209
 0.9
chr13_91262379_91262778 0.54 Gm4130
 predicted gene 4130
 160
 0.95
chr4_154603748_154603899 0.53 Gm13134
 predicted gene 13134
 2508
 0.22
chr4_63373706_63374431 0.50 Akna
 AT-hook transcription factor
 7135
 0.11
chr7_28755618_28756520 0.50 Ccer2
 coiled-coil glutamate-rich protein 2
 105
 0.92
chr3_17793835_17795104 0.50 Mir124-2hg
 Mir124-2 host gene (non-protein coding)
 427
 0.75
chr1_161766766_161767491 0.49 Gm5049
 predicted gene 5049
 21072
 0.12
chr14_121137043_121138056 0.47 Farp1
 FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
 35470
 0.2
chr9_77756703_77756872 0.46 Gclc
 glutamate-cysteine ligase, catalytic subunit
 2252
 0.23
chr8_105606313_105606835 0.46 Ripor1
 RHO family interacting cell polarization regulator 1
 1319
 0.23
chr4_148593276_148593471 0.45 Srm
 spermidine synthase
 521
 0.62
chr7_4149072_4149804 0.45 Leng9
 leukocyte receptor cluster (LRC) member 9
 936
 0.34
chr7_45654411_45654773 0.44 Mamstr
 MEF2 activating motif and SAP domain containing transcriptional regulator
 10208
 0.06
chr13_42051086_42051757 0.43 Hivep1
 human immunodeficiency virus type I enhancer binding protein 1
 600
 0.73
chr4_149854254_149854922 0.43 Gm47301
 predicted gene, 47301
 36824
 0.09
chr9_102924868_102925148 0.43 Ryk
 receptor-like tyrosine kinase
 26453
 0.15
chr11_64010815_64011208 0.41 Gm12289
 predicted gene 12289
 1604
 0.42
chr19_55942541_55942745 0.40 Tcf7l2
 transcription factor 7 like 2, T cell specific, HMG box
 44334
 0.16
chr2_118599857_118600417 0.40 Bub1b
 BUB1B, mitotic checkpoint serine/threonine kinase
 19
 0.97
chr4_141149281_141149432 0.40 Fbxo42
 F-box protein 42
 1434
 0.29
chr6_127119580_127119731 0.39 Gm43126
 predicted gene 43126
 3311
 0.14
chr14_79822704_79823014 0.39 Gm6999
 predicted gene 6999
 13853
 0.16
chr5_139324497_139325782 0.39 Adap1
 ArfGAP with dual PH domains 1
 483
 0.72
chr17_55878350_55878724 0.38 Zfp119a
 zinc finger protein 119a
 393
 0.77
chr2_125122649_125123534 0.37 Myef2
 myelin basic protein expression factor 2, repressor
 323
 0.84
chr13_109631789_109631940 0.36 Pde4d
 phosphodiesterase 4D, cAMP specific
 916
 0.75
chr13_23761268_23761510 0.35 H4c1
 H4 clustered histone 1
 159
 0.77
chrX_56597033_56598019 0.35 Mmgt1
 membrane magnesium transporter 1
 543
 0.71
chr3_36568782_36568933 0.35 Ccna2
 cyclin A2
 2012
 0.21
chr12_109455257_109457986 0.35 Dlk1
 delta like non-canonical Notch ligand 1
 2426
 0.16
chr11_116657233_116658580 0.35 Prcd
 photoreceptor disc component
 750
 0.43
chr10_43739925_43740824 0.34 Gm40634
 predicted gene, 40634
 2713
 0.19
chr8_109737737_109738073 0.34 Atxn1l
 ataxin 1-like
 166
 0.94
chr16_42444471_42445397 0.33 Gap43
 growth associated protein 43
 104283
 0.07
chr17_35978858_35980224 0.33 Prr3
 proline-rich polypeptide 3
 15
 0.78
chr11_17952930_17953846 0.33 Etaa1
 Ewing tumor-associated antigen 1
 487
 0.52
chr9_124423028_124423645 0.32 Ppp2r3d
 protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
 247
 0.91
chrX_107815441_107816283 0.32 2610002M06Rik
 RIKEN cDNA 2610002M06 gene
 472
 0.57
chr8_13063174_13063450 0.31 Proz
 protein Z, vitamin K-dependent plasma glycoprotein
 2347
 0.15
chr5_110103230_110103381 0.31 Gtpbp6
 GTP binding protein 6 (putative)
 2030
 0.15
chr11_113787418_113787592 0.31 Sdk2
 sidekick cell adhesion molecule 2
 22918
 0.15
chr11_121454005_121454156 0.31 Tbcd
 tubulin-specific chaperone d
 2131
 0.23
chr5_103654994_103656209 0.30 1700016H13Rik
 RIKEN cDNA 1700016H13 gene
 122
 0.94
chr7_16296336_16297433 0.30 Ccdc9
 coiled-coil domain containing 9
 10089
 0.11
chr5_123057629_123058391 0.30 Gm6444
 predicted gene 6444
 8232
 0.09
chr11_116130078_116131204 0.30 Trim65
 tripartite motif-containing 65
 483
 0.63
chr2_180892979_180894605 0.29 Mir124a-3
 microRNA 124a-3
 248
 0.53
chr2_69722536_69723698 0.28 Ppig
 peptidyl-prolyl isomerase G (cyclophilin G)
 24
 0.96
chr16_42635132_42635376 0.28 Gm49739
 predicted gene, 49739
 28672
 0.25
chr11_75173246_75173912 0.28 Mir132
 microRNA 132
 103
 0.6
chr1_68163528_68163679 0.28 Gm37100
 predicted gene, 37100
 47056
 0.17
chr5_65955085_65956246 0.28 4930480C01Rik
 RIKEN cDNA 4930480C01 gene
 4360
 0.13
chr2_4918566_4919706 0.28 Phyh
 phytanoyl-CoA hydroxylase
 56
 0.96
chr10_80002493_80003765 0.27 Abca7
 ATP-binding cassette, sub-family A (ABC1), member 7
 5514
 0.08
chr9_119321482_119322666 0.27 Oxsr1
 oxidative-stress responsive 1
 248
 0.87
chrX_105390628_105392456 0.27 5330434G04Rik
 RIKEN cDNA 5330434G04 gene
 212
 0.93
chr9_107612115_107612807 0.27 Sema3b
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
 3232
 0.08
chr16_21796698_21797017 0.26 1300002E11Rik
 RIKEN cDNA 1300002E11 gene
 2465
 0.17
chr7_142094181_142095425 0.26 Dusp8
 dual specificity phosphatase 8
 469
 0.54
chr2_103604353_103604504 0.26 Abtb2
 ankyrin repeat and BTB (POZ) domain containing 2
 38118
 0.14
chr5_77140191_77140680 0.25 Chaer1
 cardiac hypertrophy associated epigenetic regulator 1
 183
 0.93
chr9_69364238_69364543 0.25 Gm15511
 predicted gene 15511
 143
 0.96
chr17_26537930_26538547 0.25 Gm50275
 predicted gene, 50275
 11
 0.96
chr3_94483546_94484940 0.24 Celf3
 CUGBP, Elav-like family member 3
 84
 0.93
chr4_137356552_137357603 0.24 Cdc42
 cell division cycle 42
 622
 0.64
chr1_79439702_79440415 0.23 Scg2
 secretogranin II
 16
 0.98
chr1_36071298_36072369 0.23 Hs6st1
 heparan sulfate 6-O-sulfotransferase 1
 3433
 0.18
chr2_153161085_153162219 0.23 Tm9sf4
 transmembrane 9 superfamily protein member 4
 104
 0.96
chr11_70237225_70237851 0.23 0610010K14Rik
 RIKEN cDNA 0610010K14 gene
 49
 0.9
chr1_59237625_59237950 0.23 Als2
 alsin Rho guanine nucleotide exchange factor
 556
 0.74
chr12_68997254_68997526 0.23 Gm47515
 predicted gene, 47515
 2420
 0.27
chr1_75168195_75168929 0.23 Zfand2b
 zinc finger, AN1 type domain 2B
 84
 0.91
chr2_122377464_122377895 0.23 Gm24409
 predicted gene, 24409
 7961
 0.13
chr13_83737592_83739114 0.23 Gm33366
 predicted gene, 33366
 182
 0.66
chr1_184851591_184852782 0.23 Mtarc2
 mitochondrial amidoxime reducing component 2
 5735
 0.17
chr9_22129665_22130147 0.22 Acp5
 acid phosphatase 5, tartrate resistant
 692
 0.42
chr16_4639235_4639386 0.22 Vasn
 vasorin
 631
 0.4
chr2_120609365_120609854 0.22 Haus2
 HAUS augmin-like complex, subunit 2
 14
 0.56
chrX_101290098_101290258 0.22 Med12
 mediator complex subunit 12
 2956
 0.13
chr1_171375955_171376106 0.22 Nectin4
 nectin cell adhesion molecule 4
 5675
 0.07
chr7_127208929_127209633 0.22 Mylpf
 myosin light chain, phosphorylatable, fast skeletal muscle
 382
 0.58
chr2_157006331_157006656 0.22 Dsn1
 DSN1 homolog, MIS12 kinetochore complex component
 81
 0.95
chr7_19932934_19933834 0.21 Igsf23
 immunoglobulin superfamily, member 23
 11514
 0.07
chr17_33760609_33760910 0.21 Rab11b
 RAB11B, member RAS oncogene family
 229
 0.76
chrX_16618092_16618532 0.21 Maoa
 monoamine oxidase A
 1386
 0.49
chr8_64921935_64922086 0.21 Gm45405
 predicted gene 45405
 10033
 0.12
chr1_79437543_79437779 0.21 Scg2
 secretogranin II
 2381
 0.37
chr4_107185843_107185994 0.20 Tceanc2
 transcription elongation factor A (SII) N-terminal and central domain containing 2
 6802
 0.13
chr7_13123449_13124197 0.20 Vmn1r86
 vomeronasal 1 receptor 86
 3906
 0.1
chr5_129213898_129214049 0.20 Rps16-ps2
 ribosomal protein S16, pseudogene 2
 85456
 0.08
chr19_40611236_40612509 0.20 Tctn3
 tectonic family member 3
 316
 0.59
chr16_78375773_78376721 0.20 Btg3
 BTG anti-proliferation factor 3
 563
 0.74
chr5_53994852_53995991 0.20 Stim2
 stromal interaction molecule 2
 3078
 0.32
chr17_56474107_56476457 0.20 Ptprs
 protein tyrosine phosphatase, receptor type, S
 655
 0.65
chr3_105894723_105895429 0.19 Adora3
 adenosine A3 receptor
 9345
 0.12
chr14_60384879_60385447 0.19 Amer2
 APC membrane recruitment 2
 6877
 0.22
chr5_103774852_103775003 0.19 Aff1
 AF4/FMR2 family, member 1
 9432
 0.21
chr8_84760342_84761249 0.19 Nfix
 nuclear factor I/X
 12601
 0.1
chr6_83053316_83054403 0.19 Htra2
 HtrA serine peptidase 2
 22
 0.87
chr11_35833437_35834524 0.19 Rars
 arginyl-tRNA synthetase
 481
 0.78
chr18_37800729_37801183 0.19 Pcdhgc3
 protocadherin gamma subfamily C, 3
 5408
 0.06
chr7_13278800_13279459 0.18 Lig1
 ligase I, DNA, ATP-dependent
 136
 0.77
chr14_105926792_105926987 0.18 Spry2
 sprouty RTK signaling antagonist 2
 30070
 0.19
chr16_73223504_73223655 0.17 4930500H12Rik
 RIKEN cDNA 4930500H12 gene
 124591
 0.06
chr10_4491321_4491472 0.17 Gm22739
 predicted gene, 22739
 7162
 0.17
chr6_128525106_128525425 0.17 Pzp
 PZP, alpha-2-macroglobulin like
 1438
 0.23
chrX_106188534_106190478 0.17 Pgk1
 phosphoglycerate kinase 1
 2122
 0.24
chr12_110693597_110694119 0.17 Hsp90aa1
 heat shock protein 90, alpha (cytosolic), class A member 1
 434
 0.74
chr12_111943340_111944555 0.16 5033406O09Rik
 RIKEN cDNA 5033406O09 gene
 199
 0.89
chr16_75837887_75838038 0.16 Gm15554
 predicted gene 15554
 64905
 0.09
chr9_69397701_69398954 0.16 Ice2
 interactor of little elongation complex ELL subunit 2
 321
 0.86
chr10_81182846_81182997 0.16 Dapk3
 death-associated protein kinase 3
 84
 0.87
chr3_21935407_21936105 0.16 Gm43674
 predicted gene 43674
 62712
 0.12
chr8_88633608_88633759 0.16 Snx20
 sorting nexin 20
 2418
 0.26
chr9_88404072_88404710 0.16 Snx14
 sorting nexin 14
 5770
 0.14
chr1_132322108_132322259 0.16 Nuak2
 NUAK family, SNF1-like kinase, 2
 5413
 0.13
chr4_134272765_134273261 0.16 Pdik1l
 PDLIM1 interacting kinase 1 like
 14212
 0.08
chr11_69979766_69980520 0.15 Elp5
 elongator acetyltransferase complex subunit 5
 68
 0.82
chr11_88180343_88181714 0.15 Cuedc1
 CUE domain containing 1
 1275
 0.44
chr17_29859997_29860447 0.15 Mdga1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 9681
 0.17
chr1_61376694_61377204 0.14 9530026F06Rik
 RIKEN cDNA 9530026F06 gene
 1483
 0.43
chr2_59042712_59042879 0.14 Gm13557
 predicted gene 13557
 83088
 0.08
chr9_71976137_71976437 0.14 Gm37663
 predicted gene, 37663
 14984
 0.1
chr13_93939713_93939971 0.14 Gm24737
 predicted gene, 24737
 16468
 0.17
chr11_32281676_32281827 0.14 Hba-a1
 hemoglobin alpha, adult chain 1
 1760
 0.2
chr11_102632549_102633707 0.14 2810433D01Rik
 RIKEN cDNA 2810433D01 gene
 8712
 0.1
chr11_96629731_96630059 0.13 Skap1
 src family associated phosphoprotein 1
 78340
 0.07
chr11_55183909_55184222 0.13 Slc36a2
 solute carrier family 36 (proton/amino acid symporter), member 2
 1012
 0.43
chr11_54029637_54029788 0.13 Slc22a4
 solute carrier family 22 (organic cation transporter), member 4
 1622
 0.32
chr12_111946013_111946538 0.13 5033406O09Rik
 RIKEN cDNA 5033406O09 gene
 1791
 0.21
chr11_77872271_77873074 0.13 Pipox
 pipecolic acid oxidase
 10014
 0.14
chr8_12984359_12984568 0.13 Mcf2l
 mcf.2 transforming sequence-like
 167
 0.92
chr12_82469855_82470833 0.13 Gm5435
 predicted gene 5435
 26193
 0.18
chr18_86473556_86473849 0.13 Gm50384
 predicted gene, 50384
 227
 0.95
chr15_80078314_80078973 0.12 Snord83b
 small nucleolar RNA, C/D box 83B
 52
 0.93
chr10_81603027_81603178 0.12 Tle6
 transducin-like enhancer of split 6
 2029
 0.14
chr8_40510947_40511757 0.12 Cnot7
 CCR4-NOT transcription complex, subunit 7
 48
 0.87
chr2_90887830_90887981 0.12 C1qtnf4
 C1q and tumor necrosis factor related protein 4
 2045
 0.18
chr3_37422219_37422534 0.12 Spata5
 spermatogenesis associated 5
 1512
 0.26
chr8_126598039_126598520 0.12 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 4293
 0.26
chr10_81144225_81145434 0.12 Zbtb7a
 zinc finger and BTB domain containing 7a
 6876
 0.07
chr6_57702379_57703390 0.12 Lancl2
 LanC (bacterial lantibiotic synthetase component C)-like 2
 203
 0.91
chr5_137149473_137149929 0.11 Muc3
 mucin 3, intestinal
 379
 0.75
chr8_94704045_94704876 0.11 Pllp
 plasma membrane proteolipid
 8182
 0.12
chr1_92473017_92473751 0.11 Ndufa10
 NADH:ubiquinone oxidoreductase subunit A10
 363
 0.78
chr1_165999821_165999972 0.11 Pou2f1
 POU domain, class 2, transcription factor 1
 2713
 0.21
chr2_32166741_32168109 0.11 Gm27805
 predicted gene, 27805
 5746
 0.13
chr5_107687686_107688880 0.11 5830411K02Rik
 RIKEN cDNA 5830411K02 gene
 112
 0.7
chr14_105071055_105071206 0.11 Gm5671
 predicted gene 5671
 27680
 0.17
chr2_122380394_122381168 0.11 Gm24409
 predicted gene, 24409
 4859
 0.15
chr3_116421092_116421666 0.10 Cdc14a
 CDC14 cell division cycle 14A
 1270
 0.39
chrX_8145862_8146216 0.10 Rbm3os
 RNA binding motif protein 3, opposite strand
 122
 0.54
chr11_90685580_90685876 0.10 Tom1l1
 target of myb1-like 1 (chicken)
 1851
 0.38
chr13_19343314_19343465 0.10 Stard3nl
 STARD3 N-terminal like
 15736
 0.2
chr12_76676350_76677514 0.10 Sptb
 spectrin beta, erythrocytic
 33091
 0.15
chr6_124810954_124811934 0.10 Tpi1
 triosephosphate isomerase 1
 442
 0.58
chr2_105668422_105670370 0.10 Pax6
 paired box 6
 461
 0.65
chr17_33926039_33926463 0.10 Tapbp
 TAP binding protein
 133
 0.83
chr6_88041235_88041766 0.10 Gm44187
 predicted gene, 44187
 967
 0.4

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.6 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 0.6 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:0071688 skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.4 GO:0002254 kinin cascade(GO:0002254)
0.1 0.6 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.3 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.1 0.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.2 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.5 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.5 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.0 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.2 GO:2000489 regulation of hepatic stellate cell activation(GO:2000489)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.0 GO:1904023 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:0014041 regulation of neuron maturation(GO:0014041)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.0 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.0 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.0 0.1 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.0 GO:0071029 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.0 0.0 GO:0097503 sialylation(GO:0097503)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.0 GO:0035627 ceramide transport(GO:0035627)
0.0 0.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.0 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.5 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.1 GO:0042581 specific granule(GO:0042581)
0.1 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.3 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0019976 interleukin-2 binding(GO:0019976)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0080011 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 0.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.0 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway