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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Batf3

Z-value: 0.50

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Transcription factors associated with Batf3

Gene Symbol	Gene ID	Gene Info
Batf3 Ensembl NCBI MGI UniProt	ENSMUSG00000026630.4	Batf3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Batf3	chr1_191097653_191098840	79	0.950610	-0.36	4.8e-03	Click!
Batf3	chr1_191097128_191097279	644	0.578474	-0.15	2.7e-01	Click!
Batf3	chr1_191111232_191111383	10830	0.113981	-0.12	3.7e-01	Click!

Activity of the Batf3 motif across conditions

Conditions sorted by the z-value of the Batf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_116572624_116573264	1.74	Ube2o	ubiquitin-conjugating enzyme E2O	8503	0.1
chr4_142017816_142018715	1.69	4930455G09Rik	RIKEN cDNA 4930455G09 gene	367	0.8
chr4_46040988_46042013	1.45	Tmod1	tropomodulin 1	2291	0.3
chr17_34998907_34999597	1.43	Vars	valyl-tRNA synthetase	1735	0.11
chr19_5686209_5687218	1.42	Pcnx3	pecanex homolog 3	1436	0.16
chr6_57822563_57823744	1.38	Vopp1	vesicular, overexpressed in cancer, prosurvival protein 1	1487	0.3
chr6_31651754_31651924	1.35	Gm43154	predicted gene 43154	797	0.64
chr15_58575323_58575591	1.29	Fer1l6	fer-1-like 6 (C. elegans)	63048	0.12
chr15_27871217_27871844	1.26	Gm20555	predicted gene, 20555	4299	0.22
chr8_60953813_60955404	1.20	Clcn3	chloride channel, voltage-sensitive 3	140	0.95
chr7_128414548_128415092	1.07	Gm15503	predicted gene 15503	2479	0.18
chr17_53596477_53596632	1.05	Gm6919	predicted gene 6919	2109	0.26
chr8_122306253_122307213	0.93	Zfpm1	zinc finger protein, multitype 1	587	0.68
chr7_141146140_141146436	0.90	Ptdss2	phosphatidylserine synthase 2	8335	0.08
chr3_127468377_127468752	0.88	Gm44494	predicted gene, 44494	12556	0.1
chr8_70500810_70501374	0.87	Crlf1	cytokine receptor-like factor 1	41	0.94
chr6_86472299_86472450	0.86	C87436	expressed sequence C87436	8334	0.08
chr4_155893812_155895517	0.83	Acap3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	2352	0.11
chr16_92340779_92341614	0.83	Smim34	small integral membrane protein 34	11942	0.11
chr2_49730442_49730664	0.83	Kif5c	kinesin family member 5C	2058	0.38
chr17_28013120_28014046	0.79	Anks1	ankyrin repeat and SAM domain containing 1	6238	0.13
chr11_115511512_115512231	0.77	Jpt1	Jupiter microtubule associated homolog 1	2245	0.14
chr7_142088584_142090929	0.77	Dusp8	dual specificity phosphatase 8	5516	0.09
chr1_75214392_75214921	0.74	Stk16	serine/threonine kinase 16	1595	0.14
chr10_80140825_80141682	0.72	Atp5d	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	204	0.67
chr13_21935384_21936058	0.71	Zfp184	zinc finger protein 184 (Kruppel-like)	9373	0.06
chr12_109543555_109544268	0.71	Meg3	maternally expressed 3	587	0.28
chr2_129227304_129227665	0.69	A730036I17Rik	RIKEN cDNA A730036I17 gene	538	0.53
chr7_97749255_97749938	0.67	Aqp11	aquaporin 11	11307	0.16
chr2_29872842_29873027	0.67	2600006K01Rik	RIKEN cDNA 2600006K01 gene	2617	0.14
chr13_55426059_55426382	0.64	F12	coagulation factor XII (Hageman factor)	559	0.57
chr6_90466371_90466910	0.63	Klf15	Kruppel-like factor 15	240	0.86
chr7_28982862_28983600	0.63	Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	370	0.72
chr14_87140347_87141190	0.62	Diaph3	diaphanous related formin 3	375	0.89
chr15_78509793_78510375	0.59	Il2rb	interleukin 2 receptor, beta chain	14813	0.09
chr11_33039362_33039684	0.59	Rpsa-ps4	ribosomal protein S4, pseudogene 4	180	0.95
chr16_32671532_32671962	0.58	Tnk2	tyrosine kinase, non-receptor, 2	1407	0.33
chr13_54687874_54688432	0.58	Rnf44	ring finger protein 44	35	0.96
chr6_124463804_124465512	0.58	Clstn3	calsyntenin 3	136	0.92
chr7_19022230_19023942	0.57	Foxa3	forkhead box A3	452	0.57
chr2_105673131_105674553	0.55	Pax6	paired box 6	121	0.95
chr2_30929161_30930147	0.54	Ptges	prostaglandin E synthase	209	0.9
chr13_91262379_91262778	0.54	Gm4130	predicted gene 4130	160	0.95
chr4_154603748_154603899	0.53	Gm13134	predicted gene 13134	2508	0.22
chr4_63373706_63374431	0.50	Akna	AT-hook transcription factor	7135	0.11
chr7_28755618_28756520	0.50	Ccer2	coiled-coil glutamate-rich protein 2	105	0.92
chr3_17793835_17795104	0.50	Mir124-2hg	Mir124-2 host gene (non-protein coding)	427	0.75
chr1_161766766_161767491	0.49	Gm5049	predicted gene 5049	21072	0.12
chr14_121137043_121138056	0.47	Farp1	FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)	35470	0.2
chr9_77756703_77756872	0.46	Gclc	glutamate-cysteine ligase, catalytic subunit	2252	0.23
chr8_105606313_105606835	0.46	Ripor1	RHO family interacting cell polarization regulator 1	1319	0.23
chr4_148593276_148593471	0.45	Srm	spermidine synthase	521	0.62
chr7_4149072_4149804	0.45	Leng9	leukocyte receptor cluster (LRC) member 9	936	0.34
chr7_45654411_45654773	0.44	Mamstr	MEF2 activating motif and SAP domain containing transcriptional regulator	10208	0.06
chr13_42051086_42051757	0.43	Hivep1	human immunodeficiency virus type I enhancer binding protein 1	600	0.73
chr4_149854254_149854922	0.43	Gm47301	predicted gene, 47301	36824	0.09
chr9_102924868_102925148	0.43	Ryk	receptor-like tyrosine kinase	26453	0.15
chr11_64010815_64011208	0.41	Gm12289	predicted gene 12289	1604	0.42
chr19_55942541_55942745	0.40	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	44334	0.16
chr2_118599857_118600417	0.40	Bub1b	BUB1B, mitotic checkpoint serine/threonine kinase	19	0.97
chr4_141149281_141149432	0.40	Fbxo42	F-box protein 42	1434	0.29
chr6_127119580_127119731	0.39	Gm43126	predicted gene 43126	3311	0.14
chr14_79822704_79823014	0.39	Gm6999	predicted gene 6999	13853	0.16
chr5_139324497_139325782	0.39	Adap1	ArfGAP with dual PH domains 1	483	0.72
chr17_55878350_55878724	0.38	Zfp119a	zinc finger protein 119a	393	0.77
chr2_125122649_125123534	0.37	Myef2	myelin basic protein expression factor 2, repressor	323	0.84
chr13_109631789_109631940	0.36	Pde4d	phosphodiesterase 4D, cAMP specific	916	0.75
chr13_23761268_23761510	0.35	H4c1	H4 clustered histone 1	159	0.77
chrX_56597033_56598019	0.35	Mmgt1	membrane magnesium transporter 1	543	0.71
chr3_36568782_36568933	0.35	Ccna2	cyclin A2	2012	0.21
chr12_109455257_109457986	0.35	Dlk1	delta like non-canonical Notch ligand 1	2426	0.16
chr11_116657233_116658580	0.35	Prcd	photoreceptor disc component	750	0.43
chr10_43739925_43740824	0.34	Gm40634	predicted gene, 40634	2713	0.19
chr8_109737737_109738073	0.34	Atxn1l	ataxin 1-like	166	0.94
chr16_42444471_42445397	0.33	Gap43	growth associated protein 43	104283	0.07
chr17_35978858_35980224	0.33	Prr3	proline-rich polypeptide 3	15	0.78
chr11_17952930_17953846	0.33	Etaa1	Ewing tumor-associated antigen 1	487	0.52
chr9_124423028_124423645	0.32	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	247	0.91
chrX_107815441_107816283	0.32	2610002M06Rik	RIKEN cDNA 2610002M06 gene	472	0.57
chr8_13063174_13063450	0.31	Proz	protein Z, vitamin K-dependent plasma glycoprotein	2347	0.15
chr5_110103230_110103381	0.31	Gtpbp6	GTP binding protein 6 (putative)	2030	0.15
chr11_113787418_113787592	0.31	Sdk2	sidekick cell adhesion molecule 2	22918	0.15
chr11_121454005_121454156	0.31	Tbcd	tubulin-specific chaperone d	2131	0.23
chr5_103654994_103656209	0.30	1700016H13Rik	RIKEN cDNA 1700016H13 gene	122	0.94
chr7_16296336_16297433	0.30	Ccdc9	coiled-coil domain containing 9	10089	0.11
chr5_123057629_123058391	0.30	Gm6444	predicted gene 6444	8232	0.09
chr11_116130078_116131204	0.30	Trim65	tripartite motif-containing 65	483	0.63
chr2_180892979_180894605	0.29	Mir124a-3	microRNA 124a-3	248	0.53
chr2_69722536_69723698	0.28	Ppig	peptidyl-prolyl isomerase G (cyclophilin G)	24	0.96
chr16_42635132_42635376	0.28	Gm49739	predicted gene, 49739	28672	0.25
chr11_75173246_75173912	0.28	Mir132	microRNA 132	103	0.6
chr1_68163528_68163679	0.28	Gm37100	predicted gene, 37100	47056	0.17
chr5_65955085_65956246	0.28	4930480C01Rik	RIKEN cDNA 4930480C01 gene	4360	0.13
chr2_4918566_4919706	0.28	Phyh	phytanoyl-CoA hydroxylase	56	0.96
chr10_80002493_80003765	0.27	Abca7	ATP-binding cassette, sub-family A (ABC1), member 7	5514	0.08
chr9_119321482_119322666	0.27	Oxsr1	oxidative-stress responsive 1	248	0.87
chrX_105390628_105392456	0.27	5330434G04Rik	RIKEN cDNA 5330434G04 gene	212	0.93
chr9_107612115_107612807	0.27	Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	3232	0.08
chr16_21796698_21797017	0.26	1300002E11Rik	RIKEN cDNA 1300002E11 gene	2465	0.17
chr7_142094181_142095425	0.26	Dusp8	dual specificity phosphatase 8	469	0.54
chr2_103604353_103604504	0.26	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	38118	0.14
chr5_77140191_77140680	0.25	Chaer1	cardiac hypertrophy associated epigenetic regulator 1	183	0.93
chr9_69364238_69364543	0.25	Gm15511	predicted gene 15511	143	0.96
chr17_26537930_26538547	0.25	Gm50275	predicted gene, 50275	11	0.96
chr3_94483546_94484940	0.24	Celf3	CUGBP, Elav-like family member 3	84	0.93
chr4_137356552_137357603	0.24	Cdc42	cell division cycle 42	622	0.64
chr1_79439702_79440415	0.23	Scg2	secretogranin II	16	0.98
chr1_36071298_36072369	0.23	Hs6st1	heparan sulfate 6-O-sulfotransferase 1	3433	0.18
chr2_153161085_153162219	0.23	Tm9sf4	transmembrane 9 superfamily protein member 4	104	0.96
chr11_70237225_70237851	0.23	0610010K14Rik	RIKEN cDNA 0610010K14 gene	49	0.9
chr1_59237625_59237950	0.23	Als2	alsin Rho guanine nucleotide exchange factor	556	0.74
chr12_68997254_68997526	0.23	Gm47515	predicted gene, 47515	2420	0.27
chr1_75168195_75168929	0.23	Zfand2b	zinc finger, AN1 type domain 2B	84	0.91
chr2_122377464_122377895	0.23	Gm24409	predicted gene, 24409	7961	0.13
chr13_83737592_83739114	0.23	Gm33366	predicted gene, 33366	182	0.66
chr1_184851591_184852782	0.23	Mtarc2	mitochondrial amidoxime reducing component 2	5735	0.17
chr9_22129665_22130147	0.22	Acp5	acid phosphatase 5, tartrate resistant	692	0.42
chr16_4639235_4639386	0.22	Vasn	vasorin	631	0.4
chr2_120609365_120609854	0.22	Haus2	HAUS augmin-like complex, subunit 2	14	0.56
chrX_101290098_101290258	0.22	Med12	mediator complex subunit 12	2956	0.13
chr1_171375955_171376106	0.22	Nectin4	nectin cell adhesion molecule 4	5675	0.07
chr7_127208929_127209633	0.22	Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	382	0.58
chr2_157006331_157006656	0.22	Dsn1	DSN1 homolog, MIS12 kinetochore complex component	81	0.95
chr7_19932934_19933834	0.21	Igsf23	immunoglobulin superfamily, member 23	11514	0.07
chr17_33760609_33760910	0.21	Rab11b	RAB11B, member RAS oncogene family	229	0.76
chrX_16618092_16618532	0.21	Maoa	monoamine oxidase A	1386	0.49
chr8_64921935_64922086	0.21	Gm45405	predicted gene 45405	10033	0.12
chr1_79437543_79437779	0.21	Scg2	secretogranin II	2381	0.37
chr4_107185843_107185994	0.20	Tceanc2	transcription elongation factor A (SII) N-terminal and central domain containing 2	6802	0.13
chr7_13123449_13124197	0.20	Vmn1r86	vomeronasal 1 receptor 86	3906	0.1
chr5_129213898_129214049	0.20	Rps16-ps2	ribosomal protein S16, pseudogene 2	85456	0.08
chr19_40611236_40612509	0.20	Tctn3	tectonic family member 3	316	0.59
chr16_78375773_78376721	0.20	Btg3	BTG anti-proliferation factor 3	563	0.74
chr5_53994852_53995991	0.20	Stim2	stromal interaction molecule 2	3078	0.32
chr17_56474107_56476457	0.20	Ptprs	protein tyrosine phosphatase, receptor type, S	655	0.65
chr3_105894723_105895429	0.19	Adora3	adenosine A3 receptor	9345	0.12
chr14_60384879_60385447	0.19	Amer2	APC membrane recruitment 2	6877	0.22
chr5_103774852_103775003	0.19	Aff1	AF4/FMR2 family, member 1	9432	0.21
chr8_84760342_84761249	0.19	Nfix	nuclear factor I/X	12601	0.1
chr6_83053316_83054403	0.19	Htra2	HtrA serine peptidase 2	22	0.87
chr11_35833437_35834524	0.19	Rars	arginyl-tRNA synthetase	481	0.78
chr18_37800729_37801183	0.19	Pcdhgc3	protocadherin gamma subfamily C, 3	5408	0.06
chr7_13278800_13279459	0.18	Lig1	ligase I, DNA, ATP-dependent	136	0.77
chr14_105926792_105926987	0.18	Spry2	sprouty RTK signaling antagonist 2	30070	0.19
chr16_73223504_73223655	0.17	4930500H12Rik	RIKEN cDNA 4930500H12 gene	124591	0.06
chr10_4491321_4491472	0.17	Gm22739	predicted gene, 22739	7162	0.17
chr6_128525106_128525425	0.17	Pzp	PZP, alpha-2-macroglobulin like	1438	0.23
chrX_106188534_106190478	0.17	Pgk1	phosphoglycerate kinase 1	2122	0.24
chr12_110693597_110694119	0.17	Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	434	0.74
chr12_111943340_111944555	0.16	5033406O09Rik	RIKEN cDNA 5033406O09 gene	199	0.89
chr16_75837887_75838038	0.16	Gm15554	predicted gene 15554	64905	0.09
chr9_69397701_69398954	0.16	Ice2	interactor of little elongation complex ELL subunit 2	321	0.86
chr10_81182846_81182997	0.16	Dapk3	death-associated protein kinase 3	84	0.87
chr3_21935407_21936105	0.16	Gm43674	predicted gene 43674	62712	0.12
chr8_88633608_88633759	0.16	Snx20	sorting nexin 20	2418	0.26
chr9_88404072_88404710	0.16	Snx14	sorting nexin 14	5770	0.14
chr1_132322108_132322259	0.16	Nuak2	NUAK family, SNF1-like kinase, 2	5413	0.13
chr4_134272765_134273261	0.16	Pdik1l	PDLIM1 interacting kinase 1 like	14212	0.08
chr11_69979766_69980520	0.15	Elp5	elongator acetyltransferase complex subunit 5	68	0.82
chr11_88180343_88181714	0.15	Cuedc1	CUE domain containing 1	1275	0.44
chr17_29859997_29860447	0.15	Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	9681	0.17
chr1_61376694_61377204	0.14	9530026F06Rik	RIKEN cDNA 9530026F06 gene	1483	0.43
chr2_59042712_59042879	0.14	Gm13557	predicted gene 13557	83088	0.08
chr9_71976137_71976437	0.14	Gm37663	predicted gene, 37663	14984	0.1
chr13_93939713_93939971	0.14	Gm24737	predicted gene, 24737	16468	0.17
chr11_32281676_32281827	0.14	Hba-a1	hemoglobin alpha, adult chain 1	1760	0.2
chr11_102632549_102633707	0.14	2810433D01Rik	RIKEN cDNA 2810433D01 gene	8712	0.1
chr11_96629731_96630059	0.13	Skap1	src family associated phosphoprotein 1	78340	0.07
chr11_55183909_55184222	0.13	Slc36a2	solute carrier family 36 (proton/amino acid symporter), member 2	1012	0.43
chr11_54029637_54029788	0.13	Slc22a4	solute carrier family 22 (organic cation transporter), member 4	1622	0.32
chr12_111946013_111946538	0.13	5033406O09Rik	RIKEN cDNA 5033406O09 gene	1791	0.21
chr11_77872271_77873074	0.13	Pipox	pipecolic acid oxidase	10014	0.14
chr8_12984359_12984568	0.13	Mcf2l	mcf.2 transforming sequence-like	167	0.92
chr12_82469855_82470833	0.13	Gm5435	predicted gene 5435	26193	0.18
chr18_86473556_86473849	0.13	Gm50384	predicted gene, 50384	227	0.95
chr15_80078314_80078973	0.12	Snord83b	small nucleolar RNA, C/D box 83B	52	0.93
chr10_81603027_81603178	0.12	Tle6	transducin-like enhancer of split 6	2029	0.14
chr8_40510947_40511757	0.12	Cnot7	CCR4-NOT transcription complex, subunit 7	48	0.87
chr2_90887830_90887981	0.12	C1qtnf4	C1q and tumor necrosis factor related protein 4	2045	0.18
chr3_37422219_37422534	0.12	Spata5	spermatogenesis associated 5	1512	0.26
chr8_126598039_126598520	0.12	Irf2bp2	interferon regulatory factor 2 binding protein 2	4293	0.26
chr10_81144225_81145434	0.12	Zbtb7a	zinc finger and BTB domain containing 7a	6876	0.07
chr6_57702379_57703390	0.12	Lancl2	LanC (bacterial lantibiotic synthetase component C)-like 2	203	0.91
chr5_137149473_137149929	0.11	Muc3	mucin 3, intestinal	379	0.75
chr8_94704045_94704876	0.11	Pllp	plasma membrane proteolipid	8182	0.12
chr1_92473017_92473751	0.11	Ndufa10	NADH:ubiquinone oxidoreductase subunit A10	363	0.78
chr1_165999821_165999972	0.11	Pou2f1	POU domain, class 2, transcription factor 1	2713	0.21
chr2_32166741_32168109	0.11	Gm27805	predicted gene, 27805	5746	0.13
chr5_107687686_107688880	0.11	5830411K02Rik	RIKEN cDNA 5830411K02 gene	112	0.7
chr14_105071055_105071206	0.11	Gm5671	predicted gene 5671	27680	0.17
chr2_122380394_122381168	0.11	Gm24409	predicted gene, 24409	4859	0.15
chr3_116421092_116421666	0.10	Cdc14a	CDC14 cell division cycle 14A	1270	0.39
chrX_8145862_8146216	0.10	Rbm3os	RNA binding motif protein 3, opposite strand	122	0.54
chr11_90685580_90685876	0.10	Tom1l1	target of myb1-like 1 (chicken)	1851	0.38
chr13_19343314_19343465	0.10	Stard3nl	STARD3 N-terminal like	15736	0.2
chr12_76676350_76677514	0.10	Sptb	spectrin beta, erythrocytic	33091	0.15
chr6_124810954_124811934	0.10	Tpi1	triosephosphate isomerase 1	442	0.58
chr2_105668422_105670370	0.10	Pax6	paired box 6	461	0.65
chr17_33926039_33926463	0.10	Tapbp	TAP binding protein	133	0.83
chr6_88041235_88041766	0.10	Gm44187	predicted gene, 44187	967	0.4

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0048388	endosomal lumen acidification(GO:0048388)
0.2	0.6	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2	0.6	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.4	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.8	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.1	0.4	GO:0002254	kinin cascade(GO:0002254)
0.1	0.6	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.1	0.3	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.1	0.3	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.2	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1	0.3	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.2	GO:0045054	constitutive secretory pathway(GO:0045054)
0.1	0.3	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.3	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1	0.2	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.1	0.2	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.0	0.2	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.5	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.4	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.0	0.1	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0	0.1	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.3	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.0	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.5	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0048290	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0	0.1	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.0	0.5	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.2	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.0	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.1	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.2	GO:2000489	regulation of hepatic stellate cell activation(GO:2000489)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.0	GO:1904023	regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.0	0.1	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.1	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.3	GO:0014041	regulation of neuron maturation(GO:0014041)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0	0.0	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.0	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.1	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0071029	polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.2	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
0.0	0.0	GO:0097503	sialylation(GO:0097503)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0016237	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0015879	carnitine transport(GO:0015879)
0.0	0.0	GO:0035627	ceramide transport(GO:0035627)
0.0	0.0	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.0	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.1	0.5	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	1.1	GO:0042581	specific granule(GO:0042581)
0.1	0.2	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.4	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.3	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.4	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.2	0.5	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.8	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	0.6	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.1	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.3	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	0.3	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.1	0.2	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.5	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.4	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0046978	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.4	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.0	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.3	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0080011	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0	0.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.0	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.3	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0097001	ceramide binding(GO:0097001)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
1.6	PID CDC42 PATHWAY	CDC42 signaling events
0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.3	PID AURORA A PATHWAY	Aurora A signaling
0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway