Project

ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Bbx

Z-value: 0.76

Motif logo

Transcription factors associated with Bbx

Gene Symbol	Gene ID	Gene Info
Bbx Ensembl NCBI MGI UniProt	ENSMUSG00000022641.9	Bbx

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Bbx	chr16_50363508_50364888	33205	0.229547	-0.35	5.8e-03	Click!
Bbx	chr16_50403156_50403361	26654	0.243028	-0.33	1.1e-02	Click!
Bbx	chr16_50367228_50367379	36310	0.218872	0.31	1.5e-02	Click!
Bbx	chr16_50430464_50430776	708	0.787579	-0.27	3.4e-02	Click!
Bbx	chr16_50221557_50221752	109339	0.068951	-0.24	6.9e-02	Click!

Activity of the Bbx motif across conditions

Conditions sorted by the z-value of the Bbx motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_52699339_52699808	3.21	Akap6	A kinase (PRKA) anchor protein 6	190	0.95
chr11_41999400_42000640	3.04	Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	336	0.92
chr8_54954519_54955779	2.96	Gpm6a	glycoprotein m6a	306	0.88
chr12_29529828_29531185	2.84	Gm20208	predicted gene, 20208	609	0.74
chr13_83732205_83734272	2.75	C130071C03Rik	RIKEN cDNA C130071C03 gene	672	0.58
chr12_72234127_72234278	2.64	Rtn1	reticulon 1	1537	0.45
chr9_58197310_58202560	1.92	Islr2	immunoglobulin superfamily containing leucine-rich repeat 2	637	0.54
chr14_122479141_122479308	1.89	Zic2	zinc finger protein of the cerebellum 2	1124	0.34
chr12_102555272_102555761	1.84	Chga	chromogranin A	530	0.74
chr15_25026077_25026585	1.79	Gm2824	predicted gene 2824	1006	0.65
chr5_97222612_97223731	1.76	Gm2861	predicted gene 2861	27585	0.16
chr3_34654574_34655689	1.57	Sox2ot	SOX2 overlapping transcript (non-protein coding)	905	0.42
chr2_53501543_53502209	1.55	Gm13503	predicted gene 13503	50050	0.17
chr5_84413029_84413589	1.54	Epha5	Eph receptor A5	3497	0.31
chr9_91404809_91406365	1.53	Gm29478	predicted gene 29478	1113	0.42
chr6_15196934_15197697	1.50	Foxp2	forkhead box P2	351	0.94
chr6_86031081_86032013	1.48	Add2	adducin 2 (beta)	2800	0.16
chr6_134886811_134888239	1.36	Gpr19	G protein-coupled receptor 19	243	0.87
chr1_160350716_160351791	1.33	Rabgap1l	RAB GTPase activating protein 1-like	318	0.88
chr3_34197711_34199105	1.30	Sox2ot	SOX2 overlapping transcript (non-protein coding)	1544	0.41
chr2_124092543_124092695	1.28	Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	2650	0.37
chr2_34368351_34369364	1.19	Pbx3	pre B cell leukemia homeobox 3	1989	0.33
chr12_46816152_46816702	1.18	Nova1	NOVA alternative splicing regulator 1	533	0.8
chr17_78508180_78509392	1.18	Vit	vitrin	614	0.7
chr14_124195406_124195650	1.14	Fgf14	fibroblast growth factor 14	2626	0.41
chr19_38348426_38349048	1.12	Gm50150	predicted gene, 50150	6123	0.16
chr6_55678280_55679200	1.12	Neurod6	neurogenic differentiation 6	2523	0.32
chr4_43408488_43408639	1.12	Rusc2	RUN and SH3 domain containing 2	1234	0.34
chr16_72510590_72511319	1.10	Robo1	roundabout guidance receptor 1	52746	0.18
chr2_104406458_104406752	1.07	D430041D05Rik	RIKEN cDNA D430041D05 gene	3729	0.21
chr1_99776348_99776679	1.06	Cntnap5b	contactin associated protein-like 5B	3748	0.27
chr2_116053626_116054503	1.05	Meis2	Meis homeobox 2	4384	0.2
chr19_47017205_47017356	1.03	Nt5c2	5'-nucleotidase, cytosolic II	2127	0.2
chr9_104569742_104570707	1.02	Cpne4	copine IV	437	0.89
chr16_77418527_77418853	1.02	Gm38071	predicted gene, 38071	2066	0.19
chr13_109442519_109443753	1.02	Pde4d	phosphodiesterase 4D, cAMP specific	953	0.73
chr16_77421091_77421970	1.01	9430053O09Rik	RIKEN cDNA 9430053O09 gene	290	0.84
chr14_29718651_29719941	1.01	Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	2499	0.26
chr1_119833374_119833785	0.99	Ptpn4	protein tyrosine phosphatase, non-receptor type 4	3420	0.16
chr2_181311130_181311281	0.91	Stmn3	stathmin-like 3	3295	0.12
chr1_42693500_42693775	0.91	Pantr1	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 1	484	0.61
chr1_176811621_176811894	0.91	Cep170	centrosomal protein 170	2310	0.18
chr6_95574930_95575081	0.90	Suclg2	succinate-Coenzyme A ligase, GDP-forming, beta subunit	69004	0.13
chr15_44751090_44751715	0.90	A930017M01Rik	RIKEN cDNA A930017M01 gene	878	0.47
chr2_73776855_73777248	0.89	Chn1	chimerin 1	1705	0.39
chr3_138745098_138745249	0.89	Tspan5	tetraspanin 5	2404	0.29
chr18_79336296_79336940	0.89	Gm20593	predicted gene, 20593	11816	0.24
chr7_136196592_136196867	0.89	Gm36737	predicted gene, 36737	23433	0.22
chr10_20171692_20172198	0.88	Map7	microtubule-associated protein 7	62	0.97
chr18_25750468_25751272	0.87	Celf4	CUGBP, Elav-like family member 4	1822	0.41
chr8_102738030_102738197	0.86	Gm26301	predicted gene, 26301	5629	0.2
chr9_40949123_40949736	0.86	Jhy	junctional cadherin complex regulator	12904	0.15
chr3_107040280_107040795	0.85	AI504432	expressed sequence AI504432	1033	0.48
chr4_102760289_102761654	0.84	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	446	0.87
chr3_45382505_45382699	0.83	Pcdh10	protocadherin 10	31	0.97
chr1_168426195_168428871	0.82	Pbx1	pre B cell leukemia homeobox 1	3971	0.3
chr9_41582824_41584205	0.82	Mir125b-1	microRNA 125b-1	1588	0.2
chr4_23787162_23787456	0.81	Gm11890	predicted gene 11890	126965	0.06
chr2_74713120_74713846	0.81	Hoxd3os1	homeobox D3, opposite strand 1	957	0.21
chr6_55680954_55681113	0.80	Neurod6	neurogenic differentiation 6	230	0.94
chr8_31912793_31913158	0.80	Nrg1	neuregulin 1	4675	0.26
chr4_76445756_76446479	0.80	Ptprd	protein tyrosine phosphatase, receptor type, D	3863	0.26
chr4_110284889_110285145	0.78	Elavl4	ELAV like RNA binding protein 4	1599	0.53
chr14_45643431_45644460	0.77	Ddhd1	DDHD domain containing 1	11582	0.11
chr13_73117045_73117937	0.77	Rpl31-ps2	ribosomal protein L31, pseudogene 2	115904	0.06
chr1_41745210_41745391	0.77	Gm29260	predicted gene 29260	36508	0.23
chr2_116070605_116071583	0.77	G630016G05Rik	RIKEN cDNA G630016G05 gene	3126	0.2
chr16_6840364_6841436	0.77	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	31678	0.26
chr5_124184090_124186568	0.76	Pitpnm2	phosphatidylinositol transfer protein, membrane-associated 2	211	0.9
chr3_86916539_86917233	0.75	Dclk2	doublecortin-like kinase 2	3284	0.19
chr2_116073034_116073185	0.73	2810405F15Rik	RIKEN cDNA 2810405F15 gene	2987	0.22
chr2_14740186_14740953	0.72	Gm10848	predicted gene 10848	847	0.36
chr9_56271539_56272112	0.72	Gm37842	predicted gene, 37842	8226	0.15
chr1_25828771_25829000	0.71	Adgrb3	adhesion G protein-coupled receptor B3	626	0.54
chr12_117157079_117158175	0.71	Gm10421	predicted gene 10421	5976	0.31
chr4_13747506_13748460	0.71	Runx1t1	RUNX1 translocation partner 1	3314	0.37
chr16_16558986_16560577	0.70	Fgd4	FYVE, RhoGEF and PH domain containing 4	209	0.94
chr2_168763687_168764691	0.70	Sall4	spalt like transcription factor 4	1057	0.46
chr5_134101199_134101480	0.69	Castor2	cytosolic arginine sensor for mTORC1 subunit 2	1334	0.34
chr4_83500387_83501209	0.69	Gm11414	predicted gene 11414	37	0.96
chr11_23495316_23495877	0.69	Ahsa2	AHA1, activator of heat shock protein ATPase 2	1942	0.18
chr14_68119415_68119566	0.69	Nefm	neurofilament, medium polypeptide	5356	0.18
chr13_84056577_84057434	0.68	Gm17750	predicted gene, 17750	7767	0.22
chr11_32002849_32003000	0.68	Nsg2	neuron specific gene family member 2	2422	0.32
chr3_80799469_80799764	0.68	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	2963	0.34
chr12_72234504_72235243	0.68	Rtn1	reticulon 1	866	0.66
chr9_72533965_72534704	0.67	Rfx7	regulatory factor X, 7	1599	0.21
chr7_78881545_78881696	0.67	Mir7-2	microRNA 7-2	6657	0.12
chr9_100686193_100686344	0.67	Gm38297	predicted gene, 38297	16945	0.16
chr2_71775138_71775706	0.67	Itga6	integrin alpha 6	11507	0.13
chr4_24429141_24429555	0.67	Gm27243	predicted gene 27243	1542	0.44
chr2_97471929_97472576	0.67	Lrrc4c	leucine rich repeat containing 4C	4163	0.36
chr3_86844695_86844863	0.66	Gm37025	predicted gene, 37025	19713	0.17
chrX_57766985_57767599	0.66	Gm14631	predicted gene 14631	13424	0.18
chr2_131351541_131352096	0.66	Rnf24	ring finger protein 24	1044	0.45
chrX_99482036_99482258	0.66	Pja1	praja ring finger ubiquitin ligase 1	10874	0.2
chr13_36728917_36729068	0.65	Nrn1	neuritin 1	1676	0.27
chr9_91386509_91387874	0.65	Zic4	zinc finger protein of the cerebellum 4	4781	0.14
chr11_96593909_96594964	0.64	Skap1	src family associated phosphoprotein 1	104575	0.05
chr4_23636118_23636607	0.64	Gm25978	predicted gene, 25978	9617	0.24
chr2_116052028_116053362	0.64	Meis2	Meis homeobox 2	3015	0.24
chr16_77405996_77406237	0.64	Gm21816	predicted gene, 21816	5269	0.13
chr1_79450112_79451070	0.63	Scg2	secretogranin II	10471	0.24
chr7_34809611_34810148	0.63	Chst8	carbohydrate sulfotransferase 8	2793	0.31
chr10_100111299_100111726	0.63	Kitl	kit ligand	23456	0.13
chr2_36094766_36095038	0.62	Lhx6	LIM homeobox protein 6	629	0.62
chr2_6869935_6870654	0.62	Celf2	CUGBP, Elav-like family member 2	1678	0.39
chr6_36807350_36807539	0.61	Ptn	pleiotrophin	2735	0.37
chr14_118194572_118195025	0.61	4933431J24Rik	RIKEN cDNA 4933431J24 gene	14580	0.14
chr5_146584081_146585559	0.61	Gpr12	G-protein coupled receptor 12	1	0.96
chr16_91746458_91746610	0.60	Itsn1	intersectin 1 (SH3 domain protein 1A)	9565	0.15
chr18_37147091_37147753	0.59	Pcdhac2	protocadherin alpha subfamily C, 2	3919	0.14
chr15_103026302_103028215	0.58	Hoxc4	homeobox C4	7137	0.09
chr6_52105695_52105846	0.58	Halr1	Hoxa adjacent long noncoding RNA 1	2767	0.14
chr2_118772778_118773205	0.57	Phgr1	proline/histidine/glycine-rich 1	222	0.88
chrX_105389448_105389994	0.57	5330434G04Rik	RIKEN cDNA 5330434G04 gene	1807	0.32
chr6_93911862_93913573	0.57	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	213	0.95
chr10_86489595_86489929	0.57	Syn3	synapsin III	2135	0.22
chr11_77930982_77932135	0.57	Sez6	seizure related gene 6	519	0.68
chr2_80870243_80870731	0.56	Gm13700	predicted gene 13700	8205	0.15
chr14_48123838_48124177	0.56	Peli2	pellino 2	1978	0.25
chr6_138424419_138425583	0.56	Lmo3	LIM domain only 3	386	0.83
chr12_61527782_61528209	0.56	Lrfn5	leucine rich repeat and fibronectin type III domain containing 5	4047	0.23
chr2_38342005_38342312	0.56	Lhx2	LIM homeobox protein 2	1066	0.44
chr3_89327181_89327435	0.56	Efna3	ephrin A3	4343	0.08
chr9_91227777_91228605	0.55	Gm29602	predicted gene 29602	12176	0.18
chr16_7041535_7042315	0.55	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	27921	0.28
chr7_130517404_130517739	0.55	Ate1	arginyltransferase 1	1890	0.25
chrX_169837837_169837988	0.55	Mid1	midline 1	9753	0.25
chr3_16940321_16940472	0.55	Gm26485	predicted gene, 26485	117084	0.07
chr8_90956080_90956960	0.55	Chd9	chromodomain helicase DNA binding protein 9	1085	0.49
chr7_80187685_80187960	0.54	Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	944	0.4
chr4_19574638_19575636	0.54	Rmdn1	regulator of microtubule dynamics 1	25	0.98
chr6_16727216_16727889	0.54	Gm36669	predicted gene, 36669	49972	0.17
chr13_43215252_43215849	0.53	Tbc1d7	TBC1 domain family, member 7	44049	0.14
chr1_50930540_50930933	0.53	Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	3217	0.29
chr4_126427336_126427559	0.53	Ago3	argonaute RISC catalytic subunit 3	2094	0.24
chr18_42400574_42400820	0.53	Pou4f3	POU domain, class 4, transcription factor 3	5622	0.21
chr14_60636814_60637375	0.52	Spata13	spermatogenesis associated 13	2339	0.35
chr6_113991441_113991592	0.52	Gm15083	predicted gene 15083	13273	0.17
chrX_166349290_166349906	0.52	Gpm6b	glycoprotein m6b	4756	0.26
chr5_37241461_37244349	0.52	Crmp1	collapsin response mediator protein 1	171	0.95
chr2_62088849_62089086	0.52	Slc4a10	solute carrier family 4, sodium bicarbonate cotransporter-like, member 10	42322	0.19
chr14_64575544_64575771	0.52	Mir124a-1hg	Mir124-1 host gene (non-protein coding)	11674	0.15
chr2_79453025_79453285	0.52	Neurod1	neurogenic differentiation 1	3596	0.25
chr5_83678355_83678676	0.51	Gm25806	predicted gene, 25806	11610	0.22
chr9_80723838_80723989	0.51	Gm39380	predicted gene, 39380	13918	0.26
chr1_42707054_42709031	0.51	Pantr2	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2	10	0.97
chr2_140668225_140669392	0.51	Flrt3	fibronectin leucine rich transmembrane protein 3	2592	0.43
chr12_44439814_44440203	0.51	Nrcam	neuronal cell adhesion molecule	933	0.62
chr8_47285815_47285966	0.51	Stox2	storkhead box 2	3472	0.3
chr13_84905458_84906287	0.51	Gm4059	predicted gene 4059	68445	0.12
chr12_119234321_119234603	0.51	Itgb8	integrin beta 8	4308	0.26
chr11_96285767_96287533	0.50	Hoxb7	homeobox B7	27	0.93
chr3_5225663_5226074	0.50	Zfhx4	zinc finger homeodomain 4	4363	0.22
chr9_75681964_75682559	0.50	Scg3	secretogranin III	1326	0.37
chr10_87485570_87486803	0.50	Ascl1	achaete-scute family bHLH transcription factor 1	7474	0.2
chr10_105201607_105201758	0.50	Tmtc2	transmembrane and tetratricopeptide repeat containing 2	1978	0.39
chr11_30022183_30022992	0.50	Eml6	echinoderm microtubule associated protein like 6	3446	0.27
chr11_98320492_98321552	0.49	Neurod2	neurogenic differentiation 2	8626	0.1
chr13_78187267_78187418	0.49	Nr2f1	nuclear receptor subfamily 2, group F, member 1	3101	0.17
chr12_107997791_107998940	0.49	Bcl11b	B cell leukemia/lymphoma 11B	5049	0.31
chr3_124930856_124931558	0.49	Gm42825	predicted gene 42825	91698	0.09
chr3_70482765_70483095	0.49	Gm6631	predicted gene 6631	69611	0.12
chr5_63652583_63653162	0.49	Gm9954	predicted gene 9954	1978	0.33
chr6_83113475_83113626	0.49	Mogs	mannosyl-oligosaccharide glucosidase	1946	0.1
chr16_94372818_94373028	0.49	Pigp	phosphatidylinositol glycan anchor biosynthesis, class P	1081	0.39
chrX_91163821_91163972	0.49	Gm14773	predicted gene 14773	8728	0.25
chr11_103840627_103841312	0.49	Nsf	N-ethylmaleimide sensitive fusion protein	13538	0.18
chr9_41587766_41588181	0.48	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	204	0.89
chr6_107532409_107532560	0.48	Lrrn1	leucine rich repeat protein 1, neuronal	2716	0.32
chr17_78509585_78509946	0.48	Vit	vitrin	1593	0.34
chr7_62416059_62417205	0.48	Mkrn3	makorin, ring finger protein, 3	3507	0.2
chr1_166255711_166256817	0.47	Ildr2	immunoglobulin-like domain containing receptor 2	2071	0.3
chr12_44438829_44439626	0.47	Nrcam	neuronal cell adhesion molecule	152	0.96
chr3_146768414_146769205	0.47	Prkacb	protein kinase, cAMP dependent, catalytic, beta	1452	0.4
chr19_44764612_44765334	0.47	Pax2	paired box 2	5058	0.15
chr7_44312149_44312304	0.47	Shank1	SH3 and multiple ankyrin repeat domains 1	462	0.53
chr3_4796453_4796708	0.47	1110015O18Rik	RIKEN cDNA 1110015O18 gene	978	0.63
chr4_145625560_145625711	0.47	Gm13234	predicted gene 13234	6869	0.1
chr9_60686843_60686994	0.46	Lrrc49	leucine rich repeat containing 49	616	0.74
chr7_49842516_49843152	0.46	Gm44822	predicted gene 44822	28632	0.18
chr17_6320795_6321910	0.46	AC183097.1	transmembrane protein 181 (TMEM181) pseudogene	384	0.76
chr8_87474515_87474666	0.46	Gm2694	predicted gene 2694	1196	0.32
chr10_80382790_80383131	0.46	Gm22721	predicted gene, 22721	658	0.35
chr6_136535739_136536498	0.46	Atf7ip	activating transcription factor 7 interacting protein	3191	0.19
chr13_78196283_78196791	0.45	Nr2f1	nuclear receptor subfamily 2, group F, member 1	164	0.91
chr8_61261964_61262115	0.45	1700001D01Rik	RIKEN cDNA 1700001D01 gene	26833	0.17
chr13_15468099_15468909	0.45	Gli3	GLI-Kruppel family member GLI3	4524	0.2
chr5_114586312_114586463	0.45	Fam222a	family with sequence similarity 222, member A	18370	0.14
chr10_19397098_19397414	0.45	Olig3	oligodendrocyte transcription factor 3	40723	0.16
chr4_142825883_142826722	0.45	Gm37624	predicted gene, 37624	35494	0.22
chr4_6986587_6987701	0.45	Tox	thymocyte selection-associated high mobility group box	3339	0.35
chr2_9886962_9888150	0.44	Gata3	GATA binding protein 3	228	0.87
chr1_84693950_84694415	0.44	Mir5126	microRNA 5126	1657	0.28
chr5_148391071_148391222	0.44	Slc7a1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	1669	0.44
chr17_6489757_6490685	0.44	Tmem181b-ps	transmembrane protein 181B, pseudogene	23199	0.14
chr17_9167368_9168623	0.44	6530411M01Rik	RIKEN cDNA 6530411M01 gene	159	0.96
chr3_86542542_86543253	0.44	Lrba	LPS-responsive beige-like anchor	864	0.63
chr8_84928375_84929627	0.44	Mast1	microtubule associated serine/threonine kinase 1	226	0.8

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bbx

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	4.9	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.4	2.8	GO:0071420	cellular response to histamine(GO:0071420)
0.2	1.4	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.2	0.8	GO:0030035	microspike assembly(GO:0030035)
0.2	0.6	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2	0.5	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2	0.3	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2	0.6	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.1	0.4	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1	0.4	GO:0099558	maintenance of synapse structure(GO:0099558)
0.1	0.7	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.1	0.4	GO:1901536	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1	0.4	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.1	0.8	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.1	GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
0.1	2.8	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.5	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.1	0.3	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.1	0.4	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.3	GO:0072069	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.1	0.4	GO:0007412	axon target recognition(GO:0007412)
0.1	0.4	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	1.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.5	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.2	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.1	0.2	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.1	0.9	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.2	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	0.2	GO:0046959	habituation(GO:0046959)
0.1	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
0.1	0.3	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	0.2	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.1	0.8	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1	0.2	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.1	0.5	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.2	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.1	0.1	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.1	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.1	0.1	GO:0021557	oculomotor nerve development(GO:0021557)
0.1	0.2	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.1	0.2	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.2	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.1	0.2	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.2	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.1	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.2	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.2	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.2	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.2	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.6	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.3	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.4	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.8	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0031223	auditory behavior(GO:0031223)
0.0	0.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.3	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0	0.0	GO:0021603	cranial nerve formation(GO:0021603)
0.0	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.2	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.2	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.0	0.1	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.0	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0	0.3	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	1.0	GO:0035640	exploration behavior(GO:0035640)
0.0	0.1	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0	0.1	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0061549	sympathetic ganglion development(GO:0061549)
0.0	0.5	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.7	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0	0.1	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.1	GO:0072017	distal tubule development(GO:0072017)
0.0	0.5	GO:0060074	synapse maturation(GO:0060074)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.3	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0070662	mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.0	0.4	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.1	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.1	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.2	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.2	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.1	GO:0007619	courtship behavior(GO:0007619)
0.0	0.2	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.2	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.2	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.1	GO:0030578	PML body organization(GO:0030578)
0.0	0.6	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.8	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.0	GO:0031133	regulation of axon diameter(GO:0031133)
0.0	0.1	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0021604	cranial nerve structural organization(GO:0021604)
0.0	0.1	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.0	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.0	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.4	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.3	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.0	0.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.4	GO:0072663	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:2000847	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.3	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0060872	semicircular canal development(GO:0060872)
0.0	0.1	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.0	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.0	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.1	GO:1904252	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0	0.1	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.8	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	1.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0019732	antifungal humoral response(GO:0019732)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.1	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.0	GO:0072553	terminal button organization(GO:0072553)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0009642	response to light intensity(GO:0009642)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0	0.1	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.2	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.2	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.2	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.0	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.0	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
0.0	0.0	GO:1903367	positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0	0.0	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.0	0.0	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.3	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.0	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0021871	forebrain regionalization(GO:0021871)
0.0	0.1	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.2	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.0	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.0	0.0	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.3	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	0.0	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.0	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.0	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.2	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.0	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.0	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.9	GO:0007612	learning(GO:0007612)
0.0	0.0	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:0032484	Ral protein signal transduction(GO:0032484)
0.0	0.0	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.0	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.1	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.0	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.1	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.0	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0	0.1	GO:0030953	astral microtubule organization(GO:0030953)
0.0	0.0	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0	0.0	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.0	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3	1.3	GO:0042583	chromaffin granule(GO:0042583)
0.2	3.1	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2	1.3	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	2.9	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.8	GO:0005883	neurofilament(GO:0005883)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.8	GO:0043194	axon initial segment(GO:0043194)
0.1	0.3	GO:0097433	dense body(GO:0097433)
0.1	0.5	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.3	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.1	0.4	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.3	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	1.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.3	GO:0070578	RISC-loading complex(GO:0070578)
0.0	1.1	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.5	GO:0031045	dense core granule(GO:0031045)
0.0	0.4	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0098553	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.3	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.4	GO:0043196	varicosity(GO:0043196)
0.0	0.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	3.4	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.2	GO:0097440	apical dendrite(GO:0097440)
0.0	0.6	GO:0031941	filamentous actin(GO:0031941)
0.0	1.1	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.0	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.3	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.2	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0031261	DNA replication preinitiation complex(GO:0031261)
0.0	0.0	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.9	GO:0043495	protein anchor(GO:0043495)
0.2	1.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.2	0.5	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.2	3.1	GO:0004890	GABA-A receptor activity(GO:0004890)
0.2	0.8	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.4	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.1	0.6	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.4	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.6	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.5	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.1	0.2	GO:0016917	G-protein coupled GABA receptor activity(GO:0004965) GABA receptor activity(GO:0016917)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.2	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.2	GO:0005502	11-cis retinal binding(GO:0005502)
0.1	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.2	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.2	GO:0051373	FATZ binding(GO:0051373)
0.0	0.4	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.6	GO:0031005	filamin binding(GO:0031005)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	1.0	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.4	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	3.0	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.5	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.6	GO:0004119	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.4	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0052687	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.4	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.8	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.4	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.3	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.5	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.0	GO:1990190	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.5	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.2	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.3	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.1	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.4	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.9	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	2.9	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
1.3	PID NOTCH PATHWAY	Notch signaling pathway
0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	PID CDC42 PATHWAY	CDC42 signaling events
0.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	0.6	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	Genes involved in Signaling by TGF-beta Receptor Complex
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.2	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling