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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Cbfb

Z-value: 0.34

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Transcription factors associated with Cbfb

Gene Symbol Gene ID Gene Info
Cbfb
ENSMUSG00000031885.7 core binding factor beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr8_105169586_105169737Cbfb10130.332321-0.411.2e-03Click!
chr8_105170752_105171814Cbfb1740.868766-0.228.5e-02Click!
chr8_105170135_105170411Cbfb4010.6999020.191.5e-01Click!

Activity of the Cbfb motif across conditions

Conditions sorted by the z-value of the Cbfb motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_32167230_32167769 0.48 Ncoa4
 nuclear receptor coactivator 4
 1378
 0.28
chr11_83065104_83067047 0.32 Slfn2
 schlafen 2
 963
 0.31
chr4_49548394_49548727 0.31 Aldob
 aldolase B, fructose-bisphosphate
 986
 0.46
chr2_32081622_32082932 0.30 Fam78a
 family with sequence similarity 78, member A
 1506
 0.26
chr3_100485235_100486511 0.29 Tent5c
 terminal nucleotidyltransferase 5C
 3321
 0.18
chr6_90619935_90620303 0.28 Slc41a3
 solute carrier family 41, member 3
 972
 0.47
chr2_158145151_158146425 0.27 Tgm2
 transglutaminase 2, C polypeptide
 578
 0.71
chr6_146220162_146220523 0.27 Itpr2
 inositol 1,4,5-triphosphate receptor 2
 7201
 0.26
chr1_87620304_87621692 0.27 Inpp5d
 inositol polyphosphate-5-phosphatase D
 371
 0.85
chr2_27246009_27247328 0.26 Sardh
 sarcosine dehydrogenase
 180
 0.94
chr1_126603873_126604673 0.26 Nckap5
 NCK-associated protein 5
 111346
 0.07
chr11_96928897_96930218 0.25 Prr15l
 proline rich 15-like
 163
 0.89
chr2_180724979_180726144 0.25 Slc17a9
 solute carrier family 17, member 9
 161
 0.92
chr19_20389423_20390852 0.25 Anxa1
 annexin A1
 514
 0.81
chr7_75586786_75587711 0.25 Akap13
 A kinase (PRKA) anchor protein 13
 22791
 0.17
chr8_67948178_67948899 0.25 Psd3
 pleckstrin and Sec7 domain containing 3
 3341
 0.28
chr7_97748648_97749068 0.24 Aqp11
 aquaporin 11
 10569
 0.16
chr18_11058575_11059292 0.24 Gata6
 GATA binding protein 6
 114
 0.97
chrX_6579571_6580274 0.24 Shroom4
 shroom family member 4
 2636
 0.42
chr14_63270328_63271232 0.24 Gata4
 GATA binding protein 4
 344
 0.87
chr3_116860215_116860366 0.23 Frrs1
 ferric-chelate reductase 1
 723
 0.56
chr16_34922552_34923302 0.23 Mylk
 myosin, light polypeptide kinase
 7415
 0.19
chr15_41751298_41752572 0.23 Oxr1
 oxidation resistance 1
 234
 0.95
chr15_5107710_5108629 0.23 Card6
 caspase recruitment domain family, member 6
 315
 0.81
chr8_120292266_120293650 0.23 Gse1
 genetic suppressor element 1, coiled-coil protein
 64502
 0.09
chr16_42907540_42907820 0.23 Zbtb20
 zinc finger and BTB domain containing 20
 28
 0.98
chr2_127369985_127371247 0.23 Adra2b
 adrenergic receptor, alpha 2b
 7330
 0.15
chr7_105953249_105953965 0.23 Gm4070
 predicted gene 4070
 333
 0.86
chr7_106528440_106529206 0.22 Gm8995
 predicted gene 8995
 17152
 0.19
chr8_3353366_3353932 0.22 Arhgef18
 rho/rac guanine nucleotide exchange factor (GEF) 18
 189
 0.95
chr3_102165384_102165916 0.22 Vangl1
 VANGL planar cell polarity 1
 290
 0.87
chr19_5842574_5845856 0.22 Neat1
 nuclear paraspeckle assembly transcript 1 (non-protein coding)
 1044
 0.25
chr4_63153559_63154085 0.22 Ambp
 alpha 1 microglobulin/bikunin precursor
 351
 0.86
chr19_25052648_25052861 0.22 Dock8
 dedicator of cytokinesis 8
 141
 0.97
chr7_106214634_106215341 0.21 Gvin1
 GTPase, very large interferon inducible 1
 323
 0.89
chr9_63726302_63726832 0.21 Smad3
 SMAD family member 3
 14598
 0.22
chr6_115990945_115992684 0.21 Plxnd1
 plexin D1
 3191
 0.2
chr7_78914537_78914688 0.21 Isg20
 interferon-stimulated protein
 283
 0.86
chr2_158306583_158307357 0.21 Lbp
 lipopolysaccharide binding protein
 358
 0.8
chr10_7472799_7473709 0.21 Ulbp1
 UL16 binding protein 1
 87
 0.97
chr5_38480596_38480837 0.21 Slc2a9
 solute carrier family 2 (facilitated glucose transporter), member 9
 410
 0.84
chr4_40851422_40852119 0.21 Gm25931
 predicted gene, 25931
 1368
 0.21
chr1_87636946_87637507 0.21 Inpp5d
 inositol polyphosphate-5-phosphatase D
 15552
 0.16
chr9_110709945_110711208 0.21 Ccdc12
 coiled-coil domain containing 12
 532
 0.66
chr6_38341600_38342409 0.20 Zc3hav1
 zinc finger CCCH type, antiviral 1
 12269
 0.13
chr11_79530296_79530704 0.20 Evi2
 ecotropic viral integration site 2
 59
 0.52
chr14_69278101_69278489 0.20 Gm20236
 predicted gene, 20236
 3845
 0.11
chr14_69496349_69496737 0.20 Gm37094
 predicted gene, 37094
 3847
 0.12
chr3_96830126_96830771 0.20 Pdzk1
 PDZ domain containing 1
 372
 0.68
chr11_29647613_29648153 0.20 Gm12092
 predicted gene 12092
 2374
 0.23
chr7_100854551_100855928 0.20 Relt
 RELT tumor necrosis factor receptor
 190
 0.92
chr6_125071043_125072167 0.20 Lpar5
 lysophosphatidic acid receptor 5
 328
 0.72
chr9_66157901_66159171 0.20 Dapk2
 death-associated protein kinase 2
 301
 0.9
chr5_35727461_35727612 0.20 Sh3tc1
 SH3 domain and tetratricopeptide repeats 1
 1476
 0.36
chr3_121547676_121548236 0.19 Slc44a3
 solute carrier family 44, member 3
 15552
 0.16
chr15_78844291_78845201 0.19 Cdc42ep1
 CDC42 effector protein (Rho GTPase binding) 1
 2122
 0.16
chr18_10532272_10533276 0.19 Gm24894
 predicted gene, 24894
 18632
 0.16
chr13_76581204_76581595 0.19 Mctp1
 multiple C2 domains, transmembrane 1
 1671
 0.42
chr6_48684916_48685953 0.19 Gimap4
 GTPase, IMAP family member 4
 852
 0.34
chr13_59821306_59822207 0.18 Tut7
 terminal uridylyl transferase 7
 832
 0.41
chrX_164421189_164421355 0.18 Piga
 phosphatidylinositol glycan anchor biosynthesis, class A
 1312
 0.41
chr19_21471462_21471819 0.18 Gda
 guanine deaminase
 948
 0.67
chr2_20736484_20738247 0.18 Etl4
 enhancer trap locus 4
 51
 0.98
chr8_13202008_13202379 0.18 2810030D12Rik
 RIKEN cDNA 2810030D12 gene
 1373
 0.23
chr19_53194082_53195694 0.18 Add3
 adducin 3 (gamma)
 65
 0.97
chr5_137569837_137570642 0.18 Tfr2
 transferrin receptor 2
 370
 0.67
chr12_102355566_102356003 0.18 Rin3
 Ras and Rab interactor 3
 1004
 0.59
chr10_40133248_40133524 0.18 Slc16a10
 solute carrier family 16 (monocarboxylic acid transporters), member 10
 8868
 0.14
chr5_107724563_107727169 0.17 Gfi1
 growth factor independent 1 transcription repressor
 61
 0.88
chr17_80564251_80564461 0.17 Cdkl4
 cyclin-dependent kinase-like 4
 522
 0.78
chrX_139611976_139612272 0.17 Rnf128
 ring finger protein 128
 757
 0.7
chr5_114378285_114378463 0.17 Kctd10
 potassium channel tetramerisation domain containing 10
 2109
 0.21
chr5_66114493_66114985 0.17 Rbm47
 RNA binding motif protein 47
 16548
 0.11
chr1_173741340_173741720 0.17 Ifi207
 interferon activated gene 207
 217
 0.9
chr5_123975536_123976239 0.17 Hip1r
 huntingtin interacting protein 1 related
 2259
 0.17
chr18_20552726_20553199 0.17 Tpi-rs10
 triosephosphate isomerase related sequence 10
 3598
 0.2
chr2_148441004_148443557 0.17 Cd93
 CD93 antigen
 1283
 0.41
chr3_30766411_30766610 0.17 Samd7
 sterile alpha motif domain containing 7
 10288
 0.14
chr16_5007275_5008433 0.17 Smim22
 small integral membrane protein 22
 86
 0.85
chr16_34807078_34808442 0.16 Mylk
 myosin, light polypeptide kinase
 22839
 0.23
chr14_53795405_53795967 0.16 Trav12-4
 T cell receptor alpha variable 12-4
 17083
 0.15
chr15_50361344_50361976 0.16 Gm49198
 predicted gene, 49198
 74762
 0.13
chr13_56177742_56178675 0.16 Tifab
 TRAF-interacting protein with forkhead-associated domain, family member B
 593
 0.68
chr8_71558187_71559532 0.16 Tmem221
 transmembrane protein 221
 12
 0.94
chr16_23058440_23059079 0.16 Kng1
 kininogen 1
 366
 0.69
chr11_116615542_116615779 0.16 Rhbdf2
 rhomboid 5 homolog 2
 8540
 0.1
chr2_134825693_134826026 0.16 Gm14036
 predicted gene 14036
 21910
 0.2
chr10_111996341_111997155 0.16 Glipr1
 GLI pathogenesis-related 1 (glioma)
 516
 0.75
chr19_32322600_32322981 0.16 Sgms1
 sphingomyelin synthase 1
 439
 0.87
chr19_34846228_34846905 0.16 Mir107
 microRNA 107
 25793
 0.12
chr13_56151379_56152016 0.16 Macroh2a1
 macroH2A.1 histone
 15336
 0.14
chr4_57914999_57916744 0.16 D630039A03Rik
 RIKEN cDNA D630039A03 gene
 426
 0.84
chr12_116406570_116406928 0.16 Ncapg2
 non-SMC condensin II complex, subunit G2
 1315
 0.32
chr1_58975052_58975575 0.16 Stradb
 STE20-related kinase adaptor beta
 1791
 0.24
chr6_14752485_14752674 0.15 Ppp1r3a
 protein phosphatase 1, regulatory subunit 3A
 2695
 0.42
chr13_84651738_84651962 0.15 Gm26913
 predicted gene, 26913
 39091
 0.22
chr1_156615340_156616247 0.15 Abl2
 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
 130
 0.96
chr3_36606072_36606233 0.15 Bbs7
 Bardet-Biedl syndrome 7 (human)
 7133
 0.15
chr4_53513691_53513842 0.15 Slc44a1
 solute carrier family 44, member 1
 21846
 0.2
chr10_78070047_78070198 0.15 Icosl
 icos ligand
 762
 0.53
chr13_19823886_19824322 0.15 Gpr141
 G protein-coupled receptor 141
 123
 0.97
chr6_115984719_115988278 0.15 Plxnd1
 plexin D1
 8507
 0.15
chr2_163507247_163507946 0.15 Hnf4a
 hepatic nuclear factor 4, alpha
 788
 0.49
chr18_56977658_56977824 0.15 C330018D20Rik
 RIKEN cDNA C330018D20 gene
 2373
 0.33
chr12_61093011_61093162 0.15 Gm48301
 predicted gene, 48301
 102040
 0.08
chr4_132794518_132794820 0.15 Themis2
 thymocyte selection associated family member 2
 1718
 0.23
chr16_38376199_38376921 0.15 Popdc2
 popeye domain containing 2
 4562
 0.14
chr2_127364227_127365175 0.15 Adra2b
 adrenergic receptor, alpha 2b
 1415
 0.34
chr9_42034159_42034310 0.15 Gm16214
 predicted gene 16214
 11619
 0.22
chr12_40381138_40381829 0.15 Zfp277
 zinc finger protein 277
 18599
 0.22
chr11_114072204_114072652 0.14 Sdk2
 sidekick cell adhesion molecule 2
 5382
 0.24
chr7_81122958_81123109 0.14 Slc28a1
 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
 8183
 0.15
chr2_163694593_163694992 0.14 Pkig
 protein kinase inhibitor, gamma
 754
 0.55
chr16_38350170_38350349 0.14 Cox17
 cytochrome c oxidase assembly protein 17, copper chaperone
 967
 0.41
chr15_73751801_73752472 0.14 Ptp4a3
 protein tyrosine phosphatase 4a3
 3762
 0.2
chr6_99172298_99172685 0.14 Foxp1
 forkhead box P1
 9473
 0.29
chr18_75384437_75388058 0.14 Smad7
 SMAD family member 7
 11333
 0.21
chr2_109277608_109278317 0.14 Mettl15
 methyltransferase like 15
 318
 0.9
chr15_82792748_82793304 0.14 Cyp2d26
 cytochrome P450, family 2, subfamily d, polypeptide 26
 1196
 0.3
chr9_90237661_90237812 0.14 Gm16200
 predicted gene 16200
 16111
 0.15
chr17_83845850_83847094 0.14 Haao
 3-hydroxyanthranilate 3,4-dioxygenase
 277
 0.9
chr16_23028396_23028918 0.14 Kng2
 kininogen 2
 352
 0.74
chr16_20960637_20961170 0.14 Gm18769
 predicted gene, 18769
 239
 0.91
chr2_172393314_172394463 0.14 Cass4
 Cas scaffolding protein family member 4
 12
 0.97
chr4_47294508_47294837 0.14 Col15a1
 collagen, type XV, alpha 1
 6385
 0.24
chr15_95838442_95838593 0.14 Gm17546
 predicted gene, 17546
 8445
 0.15
chr8_104101710_104103631 0.14 Cdh5
 cadherin 5
 1045
 0.43
chr7_133700764_133701966 0.14 Uros
 uroporphyrinogen III synthase
 1173
 0.35
chr14_22020334_22020654 0.14 Lrmda
 leucine rich melanocyte differentiation associated
 646
 0.58
chr9_120116040_120116439 0.14 Slc25a38
 solute carrier family 25, member 38
 1250
 0.23
chr8_13202537_13203450 0.14 2810030D12Rik
 RIKEN cDNA 2810030D12 gene
 2173
 0.16
chr18_35739288_35740804 0.14 Sting1
 stimulator of interferon response cGAMP interactor 1
 30
 0.95
chr1_173739285_173739489 0.14 Ifi207
 interferon activated gene 207
 2360
 0.2
chr4_118435800_118435951 0.14 Cdc20
 cell division cycle 20
 54
 0.95
chr12_85686314_85687645 0.14 Batf
 basic leucine zipper transcription factor, ATF-like
 310
 0.85
chr9_70385312_70385463 0.14 Mir5626
 microRNA 5626
 20366
 0.17
chr8_81012059_81012425 0.13 Gm9725
 predicted gene 9725
 1334
 0.4
chrX_133908388_133909247 0.13 Srpx2
 sushi-repeat-containing protein, X-linked 2
 369
 0.84
chr9_32698632_32699875 0.13 Ets1
 E26 avian leukemia oncogene 1, 5' domain
 2869
 0.25
chr8_84197222_84198671 0.13 Gm26887
 predicted gene, 26887
 279
 0.72
chr13_12330029_12330316 0.13 Actn2
 actinin alpha 2
 10552
 0.17
chr1_130740681_130741391 0.13 Gm28857
 predicted gene 28857
 291
 0.71
chr5_67450455_67450649 0.13 Gm20072
 predicted gene, 20072
 2927
 0.18
chr9_44515217_44515909 0.13 Cxcr5
 chemokine (C-X-C motif) receptor 5
 10858
 0.07
chr7_100465236_100467118 0.13 C2cd3
 C2 calcium-dependent domain containing 3
 770
 0.37
chr5_105409514_105410008 0.13 Gm32051
 predicted gene, 32051
 394
 0.82
chr8_36961780_36962451 0.13 Dlc1
 deleted in liver cancer 1
 8972
 0.19
chr15_81043550_81043974 0.13 Mrtfa
 myocardin related transcription factor A
 1784
 0.27
chr14_79296843_79297470 0.13 Rgcc
 regulator of cell cycle
 4489
 0.19
chr2_84843620_84843993 0.13 Slc43a1
 solute carrier family 43, member 1
 3181
 0.15
chr13_42866202_42867352 0.13 Phactr1
 phosphatase and actin regulator 1
 57
 0.98
chrX_56446273_56446502 0.13 Gm2174
 predicted gene 2174
 1578
 0.27
chr7_19011655_19012657 0.13 Irf2bp1
 interferon regulatory factor 2 binding protein 1
 8112
 0.07
chr3_105892115_105892622 0.13 Adora3
 adenosine A3 receptor
 12053
 0.11
chr5_137631381_137632304 0.13 Lrch4
 leucine-rich repeats and calponin homology (CH) domain containing 4
 1712
 0.13
chr14_75160166_75160317 0.13 Lcp1
 lymphocyte cytosolic protein 1
 14706
 0.15
chr2_35557994_35559313 0.13 Gm13446
 predicted gene 13446
 49
 0.85
chr5_134945425_134947032 0.13 Cldn4
 claudin 4
 706
 0.44
chr15_16315135_16315417 0.13 Gm6479
 predicted gene 6479
 107323
 0.07
chr8_89664040_89664191 0.13 Gm24212
 predicted gene, 24212
 3189
 0.38
chr8_79680146_79681210 0.13 Tpd52-ps
 tumor protein D52, pseudogene
 128
 0.95
chr2_65188482_65188857 0.13 Cobll1
 Cobl-like 1
 47326
 0.14
chr8_120831876_120832383 0.13 Gm26878
 predicted gene, 26878
 48077
 0.12
chr15_58594635_58595816 0.12 Fer1l6
 fer-1-like 6 (C. elegans)
 43280
 0.17
chr8_104104538_104104713 0.12 Gm29682
 predicted gene, 29682
 1248
 0.36
chrX_74427105_74427296 0.12 Ikbkg
 inhibitor of kappaB kinase gamma
 702
 0.45
chr13_51737590_51738068 0.12 Sema4d
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 3066
 0.26
chr7_25774402_25774657 0.12 Axl
 AXL receptor tyrosine kinase
 149
 0.91
chr1_182928096_182928648 0.12 Gm37542
 predicted gene, 37542
 20662
 0.18
chr3_96223834_96224156 0.12 H2bc21
 H2B clustered histone 21
 2876
 0.05
chr1_78817332_78818790 0.12 Kcne4
 potassium voltage-gated channel, Isk-related subfamily, gene 4
 1134
 0.48
chr9_113706351_113706642 0.12 Pdcd6ip
 programmed cell death 6 interacting protein
 1748
 0.38
chr4_141076285_141076997 0.12 Necap2
 NECAP endocytosis associated 2
 1584
 0.24
chrX_164373324_164374363 0.12 Vegfd
 vascular endothelial growth factor D
 465
 0.82
chr7_19266084_19266414 0.12 Vasp
 vasodilator-stimulated phosphoprotein
 297
 0.76
chr8_25542987_25545804 0.12 Gm16159
 predicted gene 16159
 9165
 0.11
chr13_100600285_100601357 0.12 Gm24261
 predicted gene, 24261
 3538
 0.14
chr10_120694138_120694963 0.12 4930471E19Rik
 RIKEN cDNA 4930471E19 gene
 4653
 0.17
chr7_145111605_145112276 0.12 Gm45181
 predicted gene 45181
 51056
 0.14
chr4_119894810_119895257 0.12 Hivep3
 human immunodeficiency virus type I enhancer binding protein 3
 80538
 0.1
chr1_161734865_161735433 0.12 Gm15429
 predicted pseudogene 15429
 7660
 0.15
chr9_85323760_85324040 0.12 Tent5a
 terminal nucleotidyltransferase 5A
 3224
 0.2
chr3_68691756_68692227 0.12 Il12a
 interleukin 12a
 464
 0.82
chr3_19650548_19651144 0.12 Trim55
 tripartite motif-containing 55
 6338
 0.16
chr9_24485798_24486436 0.12 Dpy19l1
 dpy-19-like 1 (C. elegans)
 1797
 0.39
chr4_106798811_106800382 0.12 Acot11
 acyl-CoA thioesterase 11
 194
 0.93
chr15_51918413_51918564 0.12 Gm48923
 predicted gene, 48923
 21401
 0.15
chr5_92525035_92525371 0.12 Scarb2
 scavenger receptor class B, member 2
 18370
 0.14
chr9_42461646_42462435 0.12 Tbcel
 tubulin folding cofactor E-like
 579
 0.73
chr18_32556111_32556702 0.12 Gypc
 glycophorin C
 3574
 0.26
chr2_35329508_35329682 0.12 Stom
 stomatin
 7381
 0.14
chr19_38042662_38044080 0.12 Myof
 myoferlin
 13
 0.97
chr12_7980336_7980771 0.12 Apob
 apolipoprotein B
 2774
 0.29
chrX_164141443_164141725 0.12 Ace2
 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
 1106
 0.48
chr17_35549775_35550249 0.11 Cdsn
 corneodesmosin
 2116
 0.13
chr18_13122372_13122612 0.11 Gm5240
 predicted gene 5240
 9069
 0.22
chr7_19696242_19697209 0.11 Apoe
 apolipoprotein E
 906
 0.31
chr10_45584015_45584201 0.11 Gm47504
 predicted gene, 47504
 2889
 0.24
chr4_141872806_141873468 0.11 Efhd2
 EF hand domain containing 2
 1783
 0.2
chr11_49076677_49076921 0.11 Ifi47
 interferon gamma inducible protein 47
 212
 0.86

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Cbfb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.1 0.2 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1 0.2 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.1 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0060264 regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0 0.1 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0035865 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.0 GO:0009177 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:1902996 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.1 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.0 GO:0006808 regulation of nitrogen utilization(GO:0006808)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.0 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.0 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.0 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 PID EPO PATHWAY EPO signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor