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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Cdc5l

Z-value: 0.68

Motif logo

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Transcription factors associated with Cdc5l

Gene Symbol Gene ID Gene Info
Cdc5l
ENSMUSG00000023932.8 cell division cycle 5-like (S. pombe)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_45432754_45433547Cdc5l3910.5021520.264.3e-02Click!
chr17_45361990_45362141Cdc5l536190.1096250.201.3e-01Click!
chr17_45326704_45326930Cdc5l888670.0659540.191.5e-01Click!
chr17_45318616_45318940Cdc5l969060.058838-0.181.8e-01Click!
chr17_45317989_45318514Cdc5l974330.058400-0.171.9e-01Click!

Activity of the Cdc5l motif across conditions

Conditions sorted by the z-value of the Cdc5l motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_41585694_41587243 1.96 Mir100hg
 Mir100 Mirlet7a-2 Mir125b-1 cluster host gene
 1301
 0.29
chr12_98572639_98572973 1.93 Kcnk10
 potassium channel, subfamily K, member 10
 1906
 0.26
chr4_109343653_109343847 1.81 Eps15
 epidermal growth factor receptor pathway substrate 15
 497
 0.8
chr5_148265188_148266164 1.47 Mtus2
 microtubule associated tumor suppressor candidate 2
 331
 0.91
chr13_102957236_102957434 1.39 Mast4
 microtubule associated serine/threonine kinase family member 4
 1011
 0.69
chr6_64799057_64799968 1.32 Atoh1
 atonal bHLH transcription factor 1
 70387
 0.11
chr12_70828137_70828628 1.27 Frmd6
 FERM domain containing 6
 2693
 0.24
chr12_29527051_29527810 1.23 Myt1l
 myelin transcription factor 1-like
 954
 0.62
chr10_69536775_69537233 1.22 Ank3
 ankyrin 3, epithelial
 2782
 0.32
chr18_23036665_23037864 1.16 Nol4
 nucleolar protein 4
 1392
 0.59
chr8_65036696_65037878 1.15 Apela
 apelin receptor early endogenous ligand
 49
 0.68
chr6_36808050_36808542 1.11 Ptn
 pleiotrophin
 1883
 0.46
chr2_83814030_83814462 0.99 Fam171b
 family with sequence similarity 171, member B
 1610
 0.34
chr19_59460526_59461163 0.91 Emx2
 empty spiracles homeobox 2
 1325
 0.36
chr6_13835523_13837039 0.89 Gpr85
 G protein-coupled receptor 85
 960
 0.59
chr10_62863746_62864710 0.89 Tet1
 tet methylcytosine dioxygenase 1
 1076
 0.37
chr1_25228097_25229399 0.87 Adgrb3
 adhesion G protein-coupled receptor B3
 78
 0.96
chr3_27282892_27283771 0.85 Gm37191
 predicted gene, 37191
 5271
 0.2
chr10_109664804_109665193 0.83 3110043J17Rik
 RIKEN cDNA 3110043J17 gene
 16219
 0.26
chr13_116514424_116515376 0.82 Gm47913
 predicted gene, 47913
 148636
 0.04
chr7_30088185_30088336 0.81 Gm26920
 predicted gene, 26920
 2150
 0.12
chr18_37217058_37218378 0.81 Gm10544
 predicted gene 10544
 39196
 0.08
chrX_136115088_136116396 0.80 5730412P04Rik
 RIKEN cDNA 5730412P04 gene
 11139
 0.12
chr9_3403618_3403975 0.80 Cwf19l2
 CWF19-like 2, cell cycle control (S. pombe)
 204
 0.93
chr18_13968574_13969239 0.78 Zfp521
 zinc finger protein 521
 2814
 0.38
chr6_136171003_136171483 0.77 Grin2b
 glutamate receptor, ionotropic, NMDA2B (epsilon 2)
 646
 0.69
chr14_52327318_52328620 0.76 Sall2
 spalt like transcription factor 2
 793
 0.41
chr3_57846307_57846818 0.76 Pfn2
 profilin 2
 583
 0.72
chr19_5797009_5797210 0.76 Malat1
 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
 157
 0.88
chr14_98164357_98165375 0.76 Dach1
 dachshund family transcription factor 1
 4677
 0.28
chr7_3390544_3391386 0.74 Cacng8
 calcium channel, voltage-dependent, gamma subunit 8
 282
 0.73
chr18_60925301_60926809 0.74 Camk2a
 calcium/calmodulin-dependent protein kinase II alpha
 330
 0.84
chr2_63182035_63182719 0.74 Kcnh7
 potassium voltage-gated channel, subfamily H (eag-related), member 7
 1793
 0.52
chr11_108926426_108927821 0.73 Axin2
 axin 2
 3942
 0.24
chr8_8656555_8657725 0.73 Efnb2
 ephrin B2
 4099
 0.11
chr2_105370584_105371218 0.72 Rcn1
 reticulocalbin 1
 24447
 0.22
chr18_70140801_70141850 0.72 Rab27b
 RAB27B, member RAS oncogene family
 249
 0.95
chr12_27340607_27340913 0.70 Sox11
 SRY (sex determining region Y)-box 11
 1814
 0.48
chr17_10309899_10310075 0.70 Qk
 quaking
 9374
 0.24
chr1_66323360_66324079 0.69 Map2
 microtubule-associated protein 2
 1617
 0.37
chr1_20893244_20893592 0.68 Paqr8
 progestin and adipoQ receptor family member VIII
 2812
 0.17
chr3_84952327_84953098 0.66 Fbxw7
 F-box and WD-40 domain protein 7
 566
 0.84
chr1_168430152_168430657 0.66 Pbx1
 pre B cell leukemia homeobox 1
 1100
 0.61
chr13_45389099_45389552 0.65 Mylip
 myosin regulatory light chain interacting protein
 417
 0.87
chr14_58618020_58618171 0.64 Gm25614
 predicted gene, 25614
 32305
 0.23
chr3_154570067_154570517 0.64 Tyw3
 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
 24242
 0.18
chr16_63860769_63861945 0.64 Epha3
 Eph receptor A3
 2056
 0.46
chrX_69362591_69363214 0.64 Gm14705
 predicted gene 14705
 1633
 0.4
chr3_152264342_152264493 0.63 Nexn
 nexilin
 911
 0.47
chr13_78181011_78182180 0.62 Gm38604
 predicted gene, 38604
 1564
 0.29
chr6_33250271_33250473 0.61 Exoc4
 exocyst complex component 4
 1236
 0.47
chr19_19108280_19109261 0.61 Rorb
 RAR-related orphan receptor beta
 2426
 0.42
chr1_106174865_106175693 0.60 Phlpp1
 PH domain and leucine rich repeat protein phosphatase 1
 3527
 0.22
chr7_48847211_48847926 0.60 Csrp3
 cysteine and glycine-rich protein 3
 465
 0.76
chr18_82825279_82826286 0.58 4930445N18Rik
 RIKEN cDNA 4930445N18 gene
 30112
 0.12
chr12_26533196_26533974 0.58 Gm46344
 predicted gene, 46344
 46794
 0.11
chr10_88603199_88603736 0.58 Gm48752
 predicted gene, 48752
 995
 0.39
chr6_142506733_142508000 0.58 Ldhb
 lactate dehydrogenase B
 439
 0.83
chr16_44553746_44555096 0.57 Mir3081
 microRNA 3081
 3708
 0.24
chr9_61375691_61376224 0.57 Tle3
 transducin-like enhancer of split 3
 428
 0.83
chr11_77486623_77487566 0.56 Ankrd13b
 ankyrin repeat domain 13b
 2572
 0.17
chr12_3370750_3371679 0.56 Gm48511
 predicted gene, 48511
 2785
 0.18
chr4_126779227_126779591 0.56 Gm12937
 predicted gene 12937
 17006
 0.12
chr4_82496866_82497618 0.56 Nfib
 nuclear factor I/B
 2074
 0.34
chr3_74982117_74982268 0.55 Gm37464
 predicted gene, 37464
 42423
 0.2
chr14_76420544_76421824 0.54 Tsc22d1
 TSC22 domain family, member 1
 2356
 0.39
chr9_21616943_21617223 0.54 Smarca4
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
 819
 0.44
chr10_87491430_87491970 0.53 Ascl1
 achaete-scute family bHLH transcription factor 1
 1960
 0.34
chr3_9346361_9346885 0.53 C030034L19Rik
 RIKEN cDNA C030034L19 gene
 56441
 0.13
chr3_61366040_61366196 0.53 B430305J03Rik
 RIKEN cDNA B430305J03 gene
 167
 0.94
chr14_54617129_54617280 0.53 Mir686
 microRNA 686
 419
 0.53
chr9_60686646_60686797 0.52 Lrrc49
 leucine rich repeat containing 49
 813
 0.64
chr15_87545474_87545628 0.52 Tafa5
 TAFA chemokine like family member 5
 1252
 0.64
chr11_117873489_117873785 0.52 Tha1
 threonine aldolase 1
 156
 0.9
chr13_83728524_83729044 0.52 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 678
 0.43
chr8_90958597_90958859 0.52 Chd9
 chromodomain helicase DNA binding protein 9
 3293
 0.23
chr12_86647308_86647551 0.51 Gm8504
 predicted gene 8504
 3144
 0.21
chr10_61625131_61626356 0.51 Gm28447
 predicted gene 28447
 14669
 0.12
chr12_59129648_59129986 0.51 Mia2
 MIA SH3 domain ER export factor 2
 7
 0.97
chr4_6987725_6988203 0.50 Tox
 thymocyte selection-associated high mobility group box
 2519
 0.39
chr5_127310557_127310877 0.50 9430087B13Rik
 RIKEN cDNA 9430087B13 gene
 1700
 0.41
chr14_108914298_108914499 0.50 Slitrk1
 SLIT and NTRK-like family, member 1
 240
 0.96
chr13_83987947_83988519 0.49 Gm4241
 predicted gene 4241
 242
 0.93
chr10_122044917_122045222 0.49 Srgap1
 SLIT-ROBO Rho GTPase activating protein 1
 2239
 0.24
chr6_86051805_86052622 0.48 Add2
 adducin 2 (beta)
 35
 0.96
chr6_8352545_8353207 0.48 Gm16055
 predicted gene 16055
 11260
 0.18
chr12_36313868_36315206 0.48 Sostdc1
 sclerostin domain containing 1
 398
 0.82
chr18_43207273_43208441 0.48 Stk32a
 serine/threonine kinase 32A
 180
 0.95
chr19_28009042_28009226 0.47 Rfx3
 regulatory factor X, 3 (influences HLA class II expression)
 1656
 0.37
chr5_49284738_49286021 0.47 Kcnip4
 Kv channel interacting protein 4
 280
 0.92
chr7_125393888_125394149 0.46 Gm30717
 predicted gene, 30717
 24096
 0.14
chr7_37689602_37690278 0.46 4930505M18Rik
 RIKEN cDNA 4930505M18 gene
 20141
 0.2
chr13_28949179_28949330 0.45 Sox4
 SRY (sex determining region Y)-box 4
 4459
 0.24
chr2_56454538_56455175 0.45 Mir195b
 microRNA 195b
 330955
 0.01
chr2_162658795_162659164 0.45 Ptprt
 protein tyrosine phosphatase, receptor type, T
 2115
 0.26
chr2_13175207_13176270 0.45 Gm37780
 predicted gene, 37780
 12115
 0.2
chr3_34562197_34562348 0.45 Sox2ot
 SOX2 overlapping transcript (non-protein coding)
 1880
 0.28
chr1_78192443_78193046 0.45 Pax3
 paired box 3
 4094
 0.27
chr13_67081589_67081868 0.44 Zfp708
 zinc finger protein 708
 183
 0.87
chr11_69561744_69562204 0.44 Efnb3
 ephrin B3
 1769
 0.15
chr1_126737352_126738681 0.44 Nckap5
 NCK-associated protein 5
 174
 0.97
chr7_27553482_27553949 0.44 2310022A10Rik
 RIKEN cDNA 2310022A10 gene
 429
 0.47
chr9_91369028_91370469 0.43 Zic4
 zinc finger protein of the cerebellum 4
 250
 0.86
chr7_16948034_16948663 0.43 Pnmal2
 PNMA-like 2
 3666
 0.11
chr4_124659206_124660160 0.43 Gm2164
 predicted gene 2164
 2514
 0.16
chr13_23544501_23545496 0.43 H3c7
 H3 clustered histone 7
 946
 0.19
chr10_42860045_42861117 0.43 Scml4
 Scm polycomb group protein like 4
 38
 0.96
chr14_19976049_19977076 0.43 Gng2
 guanine nucleotide binding protein (G protein), gamma 2
 131
 0.97
chr1_70725543_70726581 0.42 Vwc2l
 von Willebrand factor C domain-containing protein 2-like
 139
 0.98
chr5_117240468_117241490 0.42 Taok3
 TAO kinase 3
 519
 0.72
chr13_23561344_23562350 0.42 H3c6
 H3 clustered histone 6
 522
 0.41
chr11_34315006_34315399 0.41 Insyn2b
 inhibitory synaptic factor family member 2B
 380
 0.85
chr5_131532921_131534054 0.41 Auts2
 autism susceptibility candidate 2
 910
 0.58
chr7_73394818_73394989 0.41 Rgma
 repulsive guidance molecule family member A
 3627
 0.16
chr11_29189160_29189311 0.41 Ppp4r3b
 protein phosphatase 4 regulatory subunit 3B
 7952
 0.18
chr11_63914512_63915012 0.40 Hs3st3b1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
 7528
 0.23
chr1_59684563_59684739 0.40 Nop58
 NOP58 ribonucleoprotein
 320
 0.78
chr10_38967267_38967717 0.40 Lama4
 laminin, alpha 4
 1820
 0.42
chr16_41532916_41533606 0.40 Lsamp
 limbic system-associated membrane protein
 158
 0.98
chr7_90886512_90887836 0.40 Gm45159
 predicted gene 45159
 102
 0.88
chr7_46962989_46963387 0.40 Gm19248
 predicted gene, 19248
 4060
 0.1
chr8_121180685_121181292 0.39 5033426O07Rik
 RIKEN cDNA 5033426O07 gene
 20847
 0.15
chr1_23656325_23656702 0.39 Gm28822
 predicted gene 28822
 81926
 0.09
chr13_44841032_44841435 0.39 Jarid2
 jumonji, AT rich interactive domain 2
 450
 0.83
chr11_101628717_101628957 0.39 Rdm1
 RAD52 motif 1
 448
 0.59
chr2_19554051_19554670 0.39 4921504E06Rik
 RIKEN cDNA 4921504E06 gene
 446
 0.82
chr2_28792637_28792998 0.39 Gm13385
 predicted gene 13385
 752
 0.58
chr16_14705845_14706609 0.38 Snai2
 snail family zinc finger 2
 375
 0.9
chr10_77581317_77581531 0.38 Pttg1ip
 pituitary tumor-transforming 1 interacting protein
 296
 0.82
chr7_62407508_62407659 0.38 Mkrn3
 makorin, ring finger protein, 3
 12556
 0.15
chr6_53574522_53574673 0.38 Creb5
 cAMP responsive element binding protein 5
 1221
 0.6
chr8_69715849_69716479 0.38 Zfp869
 zinc finger protein 869
 290
 0.87
chr3_63962500_63962661 0.38 Gm26850
 predicted gene, 26850
 1053
 0.38
chr1_19212595_19213625 0.37 Tfap2b
 transcription factor AP-2 beta
 769
 0.67
chr9_101198368_101199080 0.37 Ppp2r3a
 protein phosphatase 2, regulatory subunit B'', alpha
 127
 0.94
chr14_114837724_114838180 0.37 4930524C18Rik
 RIKEN cDNA 4930524C18 gene
 5987
 0.2
chr9_22259919_22260226 0.37 Gm39307
 predicted gene, 39307
 30
 0.67
chr18_58206427_58207135 0.37 Fbn2
 fibrillin 2
 3145
 0.33
chr7_30165175_30165502 0.37 Zfp146
 zinc finger protein 146
 4353
 0.08
chr5_14025166_14026433 0.37 Sema3e
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
 523
 0.75
chr3_56179928_56180616 0.37 Nbea
 neurobeachin
 3429
 0.25
chr1_178335228_178335429 0.37 Hnrnpu
 heterogeneous nuclear ribonucleoprotein U
 782
 0.48
chr13_83735558_83735982 0.36 Gm33366
 predicted gene, 33366
 2765
 0.16
chr2_84648361_84648948 0.36 Ctnnd1
 catenin (cadherin associated protein), delta 1
 117
 0.92
chr6_116107038_116107576 0.36 Gm20404
 predicted gene 20404
 343
 0.63
chr2_94184375_94184526 0.36 Gm23630
 predicted gene, 23630
 320
 0.86
chr10_111247804_111248910 0.36 Osbpl8
 oxysterol binding protein-like 8
 289
 0.91
chr8_48740124_48740996 0.36 Tenm3
 teneurin transmembrane protein 3
 65870
 0.13
chrX_75577044_75577513 0.36 Rab39b
 RAB39B, member RAS oncogene family
 953
 0.4
chr6_39874539_39874690 0.36 Tmem178b
 transmembrane protein 178B
 1543
 0.32
chr11_104158142_104158785 0.35 Crhr1
 corticotropin releasing hormone receptor 1
 25608
 0.16
chr5_126768981_126769769 0.35 Gm33347
 predicted gene, 33347
 42091
 0.14
chr9_67428325_67429235 0.35 Tln2
 talin 2
 23
 0.98
chr7_136007847_136008710 0.35 Gm9341
 predicted gene 9341
 55480
 0.13
chr14_84444241_84444671 0.35 Pcdh17
 protocadherin 17
 893
 0.66
chrX_135993531_135994683 0.35 Arxes2
 adipocyte-related X-chromosome expressed sequence 2
 283
 0.88
chr15_79030902_79031405 0.34 Gcat
 glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
 252
 0.77
chr4_22835212_22836357 0.33 Gm24078
 predicted gene, 24078
 88653
 0.09
chr15_98900276_98900427 0.33 Dhh
 desert hedgehog
 1811
 0.14
chr6_55680133_55680881 0.33 Neurod6
 neurogenic differentiation 6
 756
 0.69
chr2_94246278_94247531 0.33 Mir670hg
 MIR670 host gene (non-protein coding)
 3566
 0.17
chr3_45382505_45382699 0.33 Pcdh10
 protocadherin 10
 31
 0.97
chr6_112880016_112880276 0.33 Srgap3
 SLIT-ROBO Rho GTPase activating protein 3
 50687
 0.11
chr15_85674019_85674170 0.32 Lncppara
 long noncoding RNA near Ppara
 20478
 0.13
chr2_104589693_104589847 0.32 Cstf3
 cleavage stimulation factor, 3' pre-RNA, subunit 3
 753
 0.54
chr3_122462128_122462287 0.32 Gm25153
 predicted gene, 25153
 2520
 0.2
chr5_84414084_84414723 0.32 Epha5
 Eph receptor A5
 2403
 0.37
chr16_13357876_13359918 0.32 Mrtfb
 myocardin related transcription factor B
 476
 0.83
chr6_6857856_6858925 0.31 Gm44094
 predicted gene, 44094
 2139
 0.2
chr9_112118202_112119292 0.31 Mir128-2
 microRNA 128-2
 36
 0.99
chr4_9269280_9270516 0.31 Clvs1
 clavesin 1
 551
 0.81
chr3_144367127_144368131 0.31 Gm43447
 predicted gene 43447
 47415
 0.13
chr13_28811365_28811516 0.31 Gm17528
 predicted gene, 17528
 15683
 0.19
chr18_23038815_23040349 0.31 Nol4
 nucleolar protein 4
 496
 0.88
chr18_10787357_10787713 0.31 Mir133a-1hg
 Mir133a-1, Mir1b and Mir1a-2 host gene
 1652
 0.2
chr3_5225104_5225624 0.31 Zfhx4
 zinc finger homeodomain 4
 3859
 0.22
chr10_18548959_18549110 0.31 Hebp2
 heme binding protein 2
 2958
 0.29
chr12_29534253_29535510 0.30 Gm20208
 predicted gene, 20208
 10
 0.8
chr7_83077268_83077474 0.30 A530021J07Rik
 Riken cDNA A530021J07 gene
 7010
 0.24
chr11_116921808_116922404 0.30 Mgat5b
 mannoside acetylglucosaminyltransferase 5, isoenzyme B
 3243
 0.21
chr2_165599571_165599939 0.30 Gm28163
 predicted gene 28163
 2032
 0.3
chr11_50325927_50326447 0.30 Canx
 calnexin
 514
 0.68
chr18_31442020_31442171 0.30 Gm26658
 predicted gene, 26658
 1777
 0.3
chr16_77645925_77646470 0.30 Mir125b-2
 microRNA 125b-2
 76
 0.58
chr13_48264468_48265300 0.30 A330033J07Rik
 RIKEN cDNA A330033J07 gene
 2261
 0.19
chr12_118926946_118927231 0.30 Abcb5
 ATP-binding cassette, sub-family B (MDR/TAP), member 5
 2508
 0.38
chr4_66025602_66025943 0.29 Gm11484
 predicted gene 11484
 328077
 0.01
chr6_113442321_113442500 0.29 Jagn1
 jagunal homolog 1
 159
 0.85
chr19_38482437_38482889 0.29 Plce1
 phospholipase C, epsilon 1
 1542
 0.46
chr19_28006304_28006455 0.29 Rfx3
 regulatory factor X, 3 (influences HLA class II expression)
 4411
 0.22
chr18_20745187_20746004 0.29 B4galt6
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
 809
 0.66
chr6_101198088_101199306 0.29 Gm26911
 predicted gene, 26911
 39
 0.89
chr1_182412012_182412163 0.28 Trp53bp2
 transformation related protein 53 binding protein 2
 2915
 0.19
chr8_92133986_92134310 0.28 Gm45332
 predicted gene 45332
 24118
 0.17
chr17_4907323_4907483 0.28 4930579D07Rik
 RIKEN cDNA 4930579D07 gene
 14416
 0.19
chr19_50676608_50676776 0.28 Gm26629
 predicted gene, 26629
 714
 0.64
chr13_83717521_83718816 0.28 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 3213
 0.17
chr14_64576826_64577138 0.28 Mir124a-1hg
 Mir124-1 host gene (non-protein coding)
 10349
 0.16
chr14_57744536_57744714 0.28 Lats2
 large tumor suppressor 2
 29
 0.96
chr17_24209746_24209897 0.28 Ntn3
 netrin 3
 290
 0.71

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.3 0.8 GO:0099558 maintenance of synapse structure(GO:0099558)
0.2 0.6 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.1 0.5 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.5 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.4 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.5 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.5 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.5 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.4 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.5 GO:0060174 limb bud formation(GO:0060174)
0.1 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.3 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1 0.5 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 0.4 GO:0072051 juxtaglomerular apparatus development(GO:0072051)
0.1 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.7 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.2 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.1 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.2 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.4 GO:0072017 distal tubule development(GO:0072017)
0.1 0.3 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.1 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.3 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.2 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 0.3 GO:0015074 DNA integration(GO:0015074)
0.1 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.2 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.2 GO:0021557 oculomotor nerve development(GO:0021557)
0.1 0.2 GO:1905005 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.1 0.1 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0061043 regulation of vascular wound healing(GO:0061043)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:1900084 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.2 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.1 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.0 GO:0090135 actin filament branching(GO:0090135)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.0 GO:0072050 S-shaped body morphogenesis(GO:0072050)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:1903887 motile primary cilium assembly(GO:1903887)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.2 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:1900113 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.2 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:1902837 amino acid import into cell(GO:1902837)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.0 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.0 GO:1903596 regulation of gap junction assembly(GO:1903596) positive regulation of gap junction assembly(GO:1903598)
0.0 0.0 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.0 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.0 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.3 GO:1902668 negative regulation of axon guidance(GO:1902668)
0.0 0.0 GO:0007494 midgut development(GO:0007494)
0.0 0.0 GO:0033121 regulation of purine nucleotide catabolic process(GO:0033121)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0000059 protein import into nucleus, docking(GO:0000059)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.0 0.0 GO:0021550 medulla oblongata development(GO:0021550)
0.0 0.0 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.0 GO:0071107 response to parathyroid hormone(GO:0071107)
0.0 0.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0035640 exploration behavior(GO:0035640)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.0 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.3 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.3 GO:0005915 zonula adherens(GO:0005915)
0.1 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0036396 MIS complex(GO:0036396)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.0 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.0 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.5 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.5 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.0 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.0 GO:0070815 procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.0 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels