Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Cebpd

Z-value: 0.66

Motif logo

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Transcription factors associated with Cebpd

Gene Symbol Gene ID Gene Info
ENSMUSG00000071637.4 Cebpd

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Cebpdchr16_15889582_1589012214360.4167290.411.1e-03Click!
Cebpdchr16_15890187_1589070020270.3217290.401.4e-03Click!
Cebpdchr16_15888456_158886481360.9612930.356.7e-03Click!
Cebpdchr16_15948263_15948760600950.1042230.255.0e-02Click!
Cebpdchr16_15886890_158882792980.902326-0.255.6e-02Click!

Activity of the Cebpd motif across conditions

Conditions sorted by the z-value of the Cebpd motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_74063958_74064195 2.15 Usp46
ubiquitin specific peptidase 46
1672
0.23
chr7_142662290_142664788 1.98 Igf2os
insulin-like growth factor 2, opposite strand
1599
0.21
chr2_146099003_146099353 1.55 Cfap61
cilia and flagella associated protein 61
51927
0.15
chr19_59360301_59360598 1.29 Pdzd8
PDZ domain containing 8
14669
0.14
chr9_22135178_22135368 1.25 Acp5
acid phosphatase 5, tartrate resistant
418
0.64
chr7_115844339_115844623 1.19 Sox6
SRY (sex determining region Y)-box 6
1624
0.52
chr5_64813424_64813709 1.15 Klf3
Kruppel-like factor 3 (basic)
1182
0.42
chr6_87809573_87810010 1.03 Rab43
RAB43, member RAS oncogene family
34
0.93
chr1_36920216_36921458 1.03 Gm38115
predicted gene, 38115
4298
0.16
chr1_170845727_170845883 1.03 Gm25235
predicted gene, 25235
12934
0.11
chr17_40806497_40806731 1.02 Crisp2
cysteine-rich secretory protein 2
389
0.82
chrX_150548792_150548974 1.02 Alas2
aminolevulinic acid synthase 2, erythroid
1424
0.29
chr11_11687647_11688276 1.00 Ikzf1
IKAROS family zinc finger 1
1516
0.33
chr2_60908134_60908409 0.99 Rbms1
RNA binding motif, single stranded interacting protein 1
19241
0.24
chr11_60933539_60933746 0.98 Map2k3
mitogen-activated protein kinase kinase 3
1576
0.25
chr2_172291007_172291294 0.97 Gm14275
predicted gene 14275
3017
0.22
chr5_96949944_96950226 0.93 Gm43144
predicted gene 43144
9788
0.11
chr5_64487848_64488419 0.92 C030018K13Rik
RIKEN cDNA C030018K13 gene
11098
0.13
chr3_142619966_142621017 0.92 Gbp2
guanylate binding protein 2
111
0.95
chr1_156213185_156214092 0.91 Fam163a
family with sequence similarity 163, member A
8612
0.17
chr15_84324521_84325304 0.91 Parvg
parvin, gamma
117
0.94
chr7_115843191_115843609 0.90 Sox6
SRY (sex determining region Y)-box 6
2705
0.39
chr17_48271543_48271790 0.89 Treml4
triggering receptor expressed on myeloid cells-like 4
773
0.51
chr9_113969760_113969977 0.88 Ubp1
upstream binding protein 1
643
0.58
chr7_109602204_109602761 0.88 Denn2b
DENN domain containing 2B
183
0.94
chr5_73190710_73191316 0.87 Gm42571
predicted gene 42571
596
0.5
chr19_17355077_17356896 0.87 Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
681
0.75
chr3_138277693_138278260 0.86 Adh1
alcohol dehydrogenase 1 (class I)
325
0.83
chr3_127914005_127914684 0.86 9830132P13Rik
RIKEN cDNA 9830132P13 gene
1828
0.27
chr3_153908033_153909893 0.86 Snord45b
small nucleolar RNA, C/D box 45B
1670
0.17
chr4_136174546_136175305 0.84 E2f2
E2F transcription factor 2
2531
0.21
chr7_102564580_102565487 0.84 Trim21
tripartite motif-containing 21
412
0.62
chr9_66067769_66068290 0.83 Snx22
sorting nexin 22
1686
0.3
chrX_139562947_139564033 0.83 Rnf128
ring finger protein 128
174
0.96
chr7_135713600_135714219 0.82 Mki67
antigen identified by monoclonal antibody Ki 67
2452
0.24
chr3_127554205_127554356 0.82 Zgrf1
zinc finger, GRF-type containing 1
647
0.38
chr3_83008148_83008803 0.80 Gm30097
predicted gene, 30097
13
0.92
chr1_51288641_51290950 0.79 Cavin2
caveolae associated 2
669
0.72
chr2_170153321_170154276 0.79 Zfp217
zinc finger protein 217
5695
0.31
chr11_84827522_84827949 0.79 Dhrs11
dehydrogenase/reductase (SDR family) member 11
1229
0.28
chr2_75703277_75703496 0.78 Nfe2l2
nuclear factor, erythroid derived 2, like 2
1103
0.32
chr10_62341499_62342686 0.77 Hk1
hexokinase 1
607
0.63
chr5_103755071_103755222 0.77 Aff1
AF4/FMR2 family, member 1
573
0.78
chr4_115057577_115059724 0.77 Tal1
T cell acute lymphocytic leukemia 1
839
0.56
chr16_90738322_90739000 0.76 Mrap
melanocortin 2 receptor accessory protein
337
0.85
chr5_143058498_143058952 0.75 Gm43378
predicted gene 43378
8682
0.14
chr2_10130283_10130630 0.74 Itih2
inter-alpha trypsin inhibitor, heavy chain 2
207
0.9
chr6_135165211_135165571 0.73 Hebp1
heme binding protein 1
2744
0.16
chr7_49450183_49451616 0.72 Nav2
neuron navigator 2
139
0.97
chr2_158307569_158307847 0.72 Lbp
lipopolysaccharide binding protein
1096
0.38
chr10_42503874_42504154 0.71 Snx3
sorting nexin 3
1724
0.37
chr17_78586604_78587654 0.70 Vit
vitrin
13184
0.2
chr8_119438566_119438717 0.70 Osgin1
oxidative stress induced growth inhibitor 1
1452
0.34
chr3_116860395_116860804 0.70 Frrs1
ferric-chelate reductase 1
1032
0.41
chr17_71291453_71291705 0.69 Emilin2
elastin microfibril interfacer 2
5668
0.16
chr2_127369985_127371247 0.69 Adra2b
adrenergic receptor, alpha 2b
7330
0.15
chr11_100848315_100848466 0.68 Stat5b
signal transducer and activator of transcription 5B
2148
0.22
chr2_163507247_163507946 0.68 Hnf4a
hepatic nuclear factor 4, alpha
788
0.49
chr2_118658847_118659012 0.67 Pak6
p21 (RAC1) activated kinase 6
4374
0.17
chr18_36558835_36558991 0.67 Ankhd1
ankyrin repeat and KH domain containing 1
1074
0.4
chr8_70616822_70617420 0.67 Lrrc25
leucine rich repeat containing 25
277
0.8
chr2_102900531_102901984 0.67 Cd44
CD44 antigen
89
0.97
chr14_79535326_79536502 0.66 Elf1
E74-like factor 1
20216
0.14
chr2_109281814_109282372 0.66 Kif18a
kinesin family member 18A
1224
0.4
chr7_80542241_80542698 0.66 Blm
Bloom syndrome, RecQ like helicase
7350
0.17
chr11_87666085_87666908 0.65 Rnf43
ring finger protein 43
1947
0.23
chr4_40847060_40847781 0.65 Mir5123
microRNA 5123
2718
0.15
chr10_42247495_42248433 0.64 Foxo3
forkhead box O3
10402
0.26
chr5_116026823_116027049 0.64 Gm13842
predicted gene 13842
1900
0.22
chr15_83075815_83076207 0.64 Serhl
serine hydrolase-like
13495
0.12
chr2_172393314_172394463 0.63 Cass4
Cas scaffolding protein family member 4
12
0.97
chr5_103755954_103756165 0.63 Aff1
AF4/FMR2 family, member 1
1486
0.44
chr1_160079308_160079663 0.63 4930562F07Rik
RIKEN cDNA 4930562F07 gene
1500
0.35
chr1_173330127_173330565 0.62 Ackr1
atypical chemokine receptor 1 (Duffy blood group)
3156
0.19
chr3_60503044_60503755 0.62 Mbnl1
muscleblind like splicing factor 1
2121
0.38
chr18_78122352_78123104 0.62 Slc14a1
solute carrier family 14 (urea transporter), member 1
603
0.79
chr4_134272765_134273261 0.62 Pdik1l
PDLIM1 interacting kinase 1 like
14212
0.08
chr4_62367830_62368055 0.61 Slc31a1
solute carrier family 31, member 1
7215
0.14
chr12_37241367_37241587 0.61 Agmo
alkylglycerol monooxygenase
164
0.97
chr7_68917284_68917934 0.61 Gm34664
predicted gene, 34664
1593
0.45
chrX_150552023_150552275 0.60 Alas2
aminolevulinic acid synthase 2, erythroid
1888
0.27
chr5_72796212_72796844 0.60 Tec
tec protein tyrosine kinase
10508
0.15
chr8_109577473_109577666 0.60 Hp
haptoglobin
1088
0.41
chr19_32181330_32181624 0.59 Sgms1
sphingomyelin synthase 1
14951
0.21
chr14_79515651_79516545 0.59 Elf1
E74-like factor 1
400
0.83
chr13_109230735_109230971 0.59 Pde4d
phosphodiesterase 4D, cAMP specific
29801
0.25
chr2_5669550_5669816 0.59 Camk1d
calcium/calmodulin-dependent protein kinase ID
6363
0.27
chr1_133755015_133755406 0.59 Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
1463
0.34
chr8_80499828_80500092 0.58 Gypa
glycophorin A
6179
0.24
chr3_127931525_127931952 0.58 9830132P13Rik
RIKEN cDNA 9830132P13 gene
15566
0.14
chr2_84938603_84938754 0.58 Slc43a3
solute carrier family 43, member 3
1788
0.25
chr2_19050155_19050623 0.58 4930426L09Rik
RIKEN cDNA 4930426L09 gene
52046
0.12
chr10_42265343_42265931 0.58 Foxo3
forkhead box O3
7271
0.26
chr7_78913499_78914279 0.58 Isg20
interferon-stimulated protein
92
0.95
chr9_103229120_103230944 0.58 Trf
transferrin
234
0.92
chr10_94545272_94546349 0.58 Tmcc3
transmembrane and coiled coil domains 3
379
0.87
chr5_91961017_91961240 0.58 Thap6
THAP domain containing 6
1261
0.27
chr10_25298849_25299177 0.57 Akap7
A kinase (PRKA) anchor protein 7
94
0.83
chr1_58962226_58962435 0.57 Trak2
trafficking protein, kinesin binding 2
11099
0.14
chr19_37702724_37702875 0.57 Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
4714
0.2
chr4_115056428_115057540 0.56 Tal1
T cell acute lymphocytic leukemia 1
454
0.78
chr3_153721362_153721840 0.56 St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
605
0.69
chr8_45887181_45888227 0.56 Pdlim3
PDZ and LIM domain 3
2184
0.22
chr1_169530247_169530426 0.56 Nuf2
NUF2, NDC80 kinetochore complex component
1075
0.58
chr4_141558806_141560164 0.56 B330016D10Rik
RIKEN cDNA B330016D10 gene
13296
0.12
chrX_74424660_74425267 0.56 Ikbkg
inhibitor of kappaB kinase gamma
325
0.78
chr1_127774249_127775459 0.56 Ccnt2
cyclin T2
690
0.44
chr8_121080367_121081368 0.55 Fendrr
Foxf1 adjacent non-coding developmental regulatory RNA
2165
0.19
chr14_60134949_60135100 0.55 Gm6913
predicted gene 6913
6039
0.17
chr3_65953043_65954518 0.55 Ccnl1
cyclin L1
787
0.49
chr11_58641514_58641665 0.55 Trim58
tripartite motif-containing 58
1124
0.26
chr9_108795225_108796865 0.55 Ip6k2
inositol hexaphosphate kinase 2
19
0.91
chr5_129778656_129779630 0.55 Psph
phosphoserine phosphatase
30
0.95
chr2_129228255_129228485 0.54 A730036I17Rik
RIKEN cDNA A730036I17 gene
348
0.74
chr16_49858909_49859129 0.54 Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
3232
0.35
chr7_141209842_141210144 0.54 Lmntd2
lamin tail domain containing 2
4084
0.08
chr4_150001060_150001849 0.54 H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
164
0.94
chr13_111656063_111656929 0.53 Mier3
MIER family member 3
24483
0.13
chr9_45040154_45041233 0.53 Mpzl2
myelin protein zero-like 2
516
0.59
chr1_134075582_134077148 0.52 Btg2
BTG anti-proliferation factor 2
2755
0.19
chr5_129005504_129005720 0.52 Stx2
syntaxin 2
2811
0.27
chr4_148940559_148941647 0.52 Casz1
castor zinc finger 1
5899
0.16
chr9_44339477_44339803 0.52 Hmbs
hydroxymethylbilane synthase
76
0.9
chr9_50692780_50693781 0.51 Dixdc1
DIX domain containing 1
519
0.7
chr7_102444287_102444743 0.51 Rrm1
ribonucleotide reductase M1
2472
0.15
chr2_148046062_148047162 0.51 Foxa2
forkhead box A2
284
0.89
chr2_26014516_26014740 0.51 Ubac1
ubiquitin associated domain containing 1
1684
0.27
chr11_44528978_44529659 0.50 Rnf145
ring finger protein 145
9013
0.18
chr18_38251246_38251397 0.50 1700086O06Rik
RIKEN cDNA 1700086O06 gene
756
0.39
chr5_97006973_97007317 0.50 Bmp2k
BMP2 inducible kinase
9456
0.14
chr12_116406570_116406928 0.50 Ncapg2
non-SMC condensin II complex, subunit G2
1315
0.32
chr11_95344797_95344960 0.50 Fam117a
family with sequence similarity 117, member A
4916
0.13
chr2_90869871_90870903 0.50 Mtch2
mitochondrial carrier 2
6928
0.11
chr9_105520039_105521535 0.50 Atp2c1
ATPase, Ca++-sequestering
360
0.86
chr15_9528105_9528650 0.49 Il7r
interleukin 7 receptor
1389
0.51
chr2_170158054_170158217 0.49 Zfp217
zinc finger protein 217
10032
0.28
chr1_79775758_79777068 0.49 Wdfy1
WD repeat and FYVE domain containing 1
270
0.51
chr8_80868770_80869328 0.49 Gm31105
predicted gene, 31105
10891
0.18
chr1_192993893_192994044 0.49 Syt14
synaptotagmin XIV
41676
0.12
chr6_52202371_52204739 0.49 Hoxa5
homeobox A5
1032
0.2
chr1_184729275_184729496 0.49 Hlx
H2.0-like homeobox
2213
0.23
chr5_122145241_122145905 0.49 Ccdc63
coiled-coil domain containing 63
4750
0.15
chr11_12035779_12037364 0.49 Grb10
growth factor receptor bound protein 10
830
0.66
chr9_76235972_76237521 0.49 Gfral
GDNF family receptor alpha like
23089
0.22
chr11_70092296_70092452 0.49 Asgr2
asialoglycoprotein receptor 2
270
0.83
chr10_34416775_34416926 0.48 Nt5dc1
5'-nucleotidase domain containing 1
1618
0.38
chr8_22807982_22809010 0.48 1700041G16Rik
RIKEN cDNA 1700041G16 gene
221
0.9
chr17_25086969_25087388 0.48 Ift140
intraflagellar transport 140
3493
0.13
chr4_40850475_40851213 0.48 Gm25931
predicted gene, 25931
442
0.43
chr15_102460089_102460942 0.48 Prr13
proline rich 13
432
0.68
chr4_132397142_132397510 0.48 Phactr4
phosphatase and actin regulator 4
873
0.38
chr8_119437994_119438145 0.48 Osgin1
oxidative stress induced growth inhibitor 1
880
0.53
chr18_80260024_80260633 0.48 Slc66a2
solute carrier family 66 member 2
2512
0.18
chr18_65802028_65802182 0.48 Sec11c
SEC11 homolog C, signal peptidase complex subunit
803
0.51
chr5_119673827_119675890 0.48 Tbx3
T-box 3
587
0.67
chr6_83246695_83246846 0.48 Slc4a5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
9395
0.12
chr7_101377838_101379825 0.48 Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
462
0.71
chr15_52967840_52967991 0.47 Ext1
exostosin glycosyltransferase 1
139953
0.05
chr17_45592643_45594205 0.47 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
210
0.86
chr3_127929911_127930327 0.47 9830132P13Rik
RIKEN cDNA 9830132P13 gene
13947
0.14
chr12_57184412_57184925 0.47 Slc25a21
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
12804
0.21
chr14_27237814_27239092 0.47 Gm49616
predicted gene, 49616
391
0.49
chr17_24847456_24847895 0.47 Fahd1
fumarylacetoacetate hydrolase domain containing 1
2689
0.12
chr16_77016557_77016761 0.47 Usp25
ubiquitin specific peptidase 25
2872
0.28
chr18_75262518_75262730 0.47 2010010A06Rik
RIKEN cDNA 2010010A06 gene
26559
0.19
chr4_147814549_147814848 0.46 Gm20707
predicted gene 20707
4858
0.11
chrX_52609355_52610313 0.46 Gpc3
glypican 3
4087
0.23
chr15_83432069_83433241 0.46 Pacsin2
protein kinase C and casein kinase substrate in neurons 2
160
0.94
chr19_46905254_46905462 0.45 Nt5c2
5'-nucleotidase, cytosolic II
4217
0.2
chr8_53636244_53636686 0.45 Neil3
nei like 3 (E. coli)
2213
0.43
chr6_38355123_38355426 0.44 Zc3hav1
zinc finger CCCH type, antiviral 1
671
0.59
chr11_70614847_70615992 0.44 Chrne
cholinergic receptor, nicotinic, epsilon polypeptide
254
0.58
chr11_69947014_69948171 0.44 Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
382
0.6
chr9_66894889_66895130 0.44 Rab8b
RAB8B, member RAS oncogene family
24678
0.13
chr16_58519371_58520301 0.43 St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
3508
0.23
chr7_103825389_103825783 0.43 Hbb-bs
hemoglobin, beta adult s chain
2139
0.11
chr11_83283019_83283399 0.43 Slfn14
schlafen 14
3517
0.11
chr7_45800366_45800681 0.43 Cyth2
cytohesin 2
10365
0.07
chr2_165898423_165899020 0.43 Zmynd8
zinc finger, MYND-type containing 8
295
0.86
chr2_91096772_91098746 0.43 Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
979
0.4
chr16_37012576_37012727 0.42 Polq
polymerase (DNA directed), theta
836
0.55
chr2_173038544_173038695 0.42 Gm14453
predicted gene 14453
4039
0.16
chr19_42584461_42584713 0.42 R3hcc1l
R3H domain and coiled-coil containing 1 like
3426
0.22
chr2_170139923_170140076 0.42 Zfp217
zinc finger protein 217
2679
0.39
chr17_35188062_35188446 0.42 Lst1
leukocyte specific transcript 1
185
0.77
chr9_70934045_70934653 0.42 Lipc
lipase, hepatic
264
0.92
chr12_84963079_84963230 0.42 Arel1
apoptosis resistant E3 ubiquitin protein ligase 1
2876
0.18
chr6_148109062_148109585 0.42 Far2os1
fatty acyl CoA reductase 2, opposite strand 1
41450
0.13
chr6_34471690_34471871 0.42 Bpgm
2,3-bisphosphoglycerate mutase
4427
0.19
chr16_58662432_58662650 0.42 Gm49701
predicted gene, 49701
7297
0.13
chr12_111442182_111444685 0.42 Tnfaip2
tumor necrosis factor, alpha-induced protein 2
771
0.51
chr4_63151303_63151507 0.42 Ambp
alpha 1 microglobulin/bikunin precursor
2768
0.24
chr7_118126848_118127762 0.41 Arl6ip1
ADP-ribosylation factor-like 6 interacting protein 1
1805
0.29
chr2_80037645_80038971 0.41 Pde1a
phosphodiesterase 1A, calmodulin-dependent
721
0.79
chr12_59096249_59096457 0.41 Mia2
MIA SH3 domain ER export factor 2
553
0.61
chr3_57426842_57427133 0.41 Tm4sf4
transmembrane 4 superfamily member 4
1673
0.42
chr1_167387093_167387564 0.41 Mgst3
microsomal glutathione S-transferase 3
6513
0.16
chr7_75656288_75656497 0.41 Akap13
A kinase (PRKA) anchor protein 13
12207
0.18
chr4_126023568_126023719 0.41 Csf3r
colony stimulating factor 3 receptor (granulocyte)
907
0.52
chr7_109637522_109637823 0.41 Denn2b
DENN domain containing 2B
20525
0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Cebpd

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 1.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.3 0.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 0.7 GO:0021564 vagus nerve development(GO:0021564)
0.2 0.8 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.8 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:1903818 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.5 GO:0097460 ferrous iron import into cell(GO:0097460)
0.1 0.5 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.6 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.3 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.1 0.3 GO:0010159 specification of organ position(GO:0010159)
0.1 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 0.3 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:0060264 regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.1 0.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.3 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.1 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.3 GO:0019086 late viral transcription(GO:0019086)
0.1 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.4 GO:0032264 IMP salvage(GO:0032264)
0.1 0.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.2 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.4 GO:0070836 caveola assembly(GO:0070836)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.2 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.1 0.3 GO:0052055 modulation by symbiont of host molecular function(GO:0052055)
0.1 0.2 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.1 0.7 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.3 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.2 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.1 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.4 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.2 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.1 0.3 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0008228 opsonization(GO:0008228)
0.1 0.2 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 1.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.9 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.4 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.1 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 0.3 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.6 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.2 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.2 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.3 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.2 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0033131 regulation of glucokinase activity(GO:0033131)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0015684 ferrous iron transport(GO:0015684)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.8 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0014735 regulation of muscle atrophy(GO:0014735)
0.0 0.2 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.6 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.1 GO:0048370 lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.0 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.2 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.2 GO:2001044 regulation of integrin-mediated signaling pathway(GO:2001044)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.2 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.0 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.2 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.0 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 1.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.0 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:2000662 interleukin-5 secretion(GO:0072603) interleukin-13 secretion(GO:0072611) regulation of interleukin-5 secretion(GO:2000662) positive regulation of interleukin-5 secretion(GO:2000664) regulation of interleukin-13 secretion(GO:2000665) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.1 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0 0.0 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.0 0.0 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.0 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.0 GO:0072141 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.0 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.0 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.0 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.0 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.0 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.0 GO:0010872 regulation of cholesterol esterification(GO:0010872)
0.0 0.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0003133 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0 0.0 GO:0003166 bundle of His development(GO:0003166)
0.0 0.0 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.0 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.7 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.0 GO:0070340 detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0072319 vesicle uncoating(GO:0072319)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0000237 leptotene(GO:0000237)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.3 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.0 GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0 0.0 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.0 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.2 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.2 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.0 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.0 GO:0046112 nucleobase biosynthetic process(GO:0046112)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.0 GO:1901679 pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.0 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:0014745 negative regulation of muscle adaptation(GO:0014745)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.0 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.0 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.0 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.2 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.0 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.0 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
0.0 0.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.5 GO:0007569 cell aging(GO:0007569)
0.0 0.1 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 1.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.2 GO:2000142 regulation of DNA-templated transcription, initiation(GO:2000142)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0097452 GAIT complex(GO:0097452)
0.1 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.0 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 1.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.0 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.0 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.0 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 0.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.5 GO:0015265 urea channel activity(GO:0015265)
0.1 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.6 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0044682 N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.1 GO:0016420 S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.2 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.7 GO:0016208 AMP binding(GO:0016208)
0.1 0.3 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.6 GO:0043176 amine binding(GO:0043176)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.3 GO:0034863 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.0 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.0 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004337 geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0018632 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:1990190 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0016749 N-succinyltransferase activity(GO:0016749)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0015932 nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.0 GO:0016015 morphogen activity(GO:0016015)
0.0 0.0 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0044823 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 2.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.0 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)