Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Creb3l2

Z-value: 0.84

Motif logo

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Transcription factors associated with Creb3l2

Gene Symbol Gene ID Gene Info
ENSMUSG00000038648.5 Creb3l2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Creb3l2chr6_37441010_374421325750.8335200.531.5e-05Click!
Creb3l2chr6_37440238_3744098815330.5142690.489.9e-05Click!
Creb3l2chr6_37354682_37355067183390.2458060.471.7e-04Click!
Creb3l2chr6_37435978_3743613060920.2906460.428.5e-04Click!
Creb3l2chr6_37430667_37431041112920.2697690.428.7e-04Click!

Activity of the Creb3l2 motif across conditions

Conditions sorted by the z-value of the Creb3l2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_11055272_11055490 2.38 Gata6
GATA binding protein 6
343
0.89
chr10_8878382_8878908 1.94 Gm26674
predicted gene, 26674
5992
0.16
chr1_183439062_183439515 1.82 Gm37214
predicted gene, 37214
18633
0.13
chr7_24462385_24463393 1.71 Plaur
plasminogen activator, urokinase receptor
389
0.71
chr1_51597257_51597674 1.63 Gm17767
predicted gene, 17767
747
0.73
chr4_11026519_11026685 1.62 Plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
18675
0.16
chr14_101886064_101886474 1.58 Lmo7
LIM domain only 7
2150
0.43
chr15_76242501_76243437 1.53 Parp10
poly (ADP-ribose) polymerase family, member 10
451
0.59
chr9_90055154_90055692 1.46 Ctsh
cathepsin H
864
0.58
chr15_66891047_66892576 1.40 Ccn4
cellular communication network factor 4
303
0.9
chr14_21078036_21078470 1.39 Adk
adenosine kinase
2101
0.35
chr2_167539777_167540513 1.38 Snai1
snail family zinc finger 1
1950
0.22
chr6_136940269_136941762 1.36 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
488
0.73
chr2_180724979_180726144 1.36 Slc17a9
solute carrier family 17, member 9
161
0.92
chr11_117781898_117782456 1.32 Tmc6
transmembrane channel-like gene family 6
21
0.57
chr15_93824709_93825690 1.30 Gm49445
predicted gene, 49445
161
0.97
chr6_53573075_53574499 1.28 Creb5
cAMP responsive element binding protein 5
411
0.9
chr11_117779316_117780928 1.28 Tmc6
transmembrane channel-like gene family 6
472
0.61
chr18_11053961_11055254 1.28 Gata6
GATA binding protein 6
431
0.83
chr6_136930581_136931368 1.22 Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
7142
0.13
chr10_81092290_81092669 1.19 Creb3l3
cAMP responsive element binding protein 3-like 3
96
0.92
chr7_78913499_78914279 1.18 Isg20
interferon-stimulated protein
92
0.95
chr19_20726887_20727042 1.17 Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
598
0.82
chr11_100415480_100416522 1.17 Fkbp10
FK506 binding protein 10
156
0.86
chr17_28007198_28009699 1.16 Anks1
ankyrin repeat and SAM domain containing 1
1103
0.37
chr2_180333754_180334993 1.15 Gata5
GATA binding protein 5
326
0.8
chr18_60963604_60964955 1.14 Camk2a
calcium/calmodulin-dependent protein kinase II alpha
679
0.59
chr12_105034229_105034527 1.12 Glrx5
glutaredoxin 5
838
0.39
chr11_103954187_103954394 1.12 Nsf
N-ethylmaleimide sensitive fusion protein
234
0.94
chr18_80617090_80617592 1.08 Nfatc1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
8366
0.19
chr15_89020705_89021425 1.07 Mov10l1
Mov10 like RISC complex RNA helicase 1
644
0.53
chr4_141746794_141747616 1.05 Agmat
agmatine ureohydrolase (agmatinase)
533
0.68
chr10_81128980_81129986 1.05 Map2k2
mitogen-activated protein kinase kinase 2
868
0.33
chr18_84858127_84859558 1.05 Gm16146
predicted gene 16146
705
0.62
chr12_33433874_33434049 1.03 Twistnb
twist basic helix-loop-helix transcription factor 1 neighbor
2820
0.21
chr10_42031249_42031528 1.03 Armc2
armadillo repeat containing 2
12946
0.18
chr10_22818712_22820254 1.03 Tcf21
transcription factor 21
676
0.65
chr12_36042503_36042830 1.00 Tspan13
tetraspanin 13
166
0.95
chr6_139576863_139577642 1.00 4930443G03Rik
RIKEN cDNA 4930443G03 gene
47
0.98
chr9_22099127_22099760 0.98 Cnn1
calponin 1
175
0.85
chr17_36160926_36162147 0.98 Gm17782
predicted gene, 17782
543
0.39
chr1_93401084_93402037 0.98 Ano7
anoctamin 7
301
0.83
chr7_24379069_24379220 0.97 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
3026
0.12
chr13_102036243_102036435 0.95 Gm38133
predicted gene, 38133
79696
0.1
chr16_24367159_24367531 0.95 Gm41434
predicted gene, 41434
2887
0.24
chr17_12741399_12742894 0.95 Airn
antisense Igf2r RNA
748
0.57
chr2_35557994_35559313 0.94 Gm13446
predicted gene 13446
49
0.85
chr1_172634773_172634935 0.93 Dusp23
dual specificity phosphatase 23
1892
0.25
chr13_13358759_13358935 0.93 Gpr137b
G protein-coupled receptor 137B
8958
0.11
chr7_126624812_126625701 0.92 Nupr1
nuclear protein transcription regulator 1
88
0.92
chr8_95020660_95021163 0.90 Adgrg3
adhesion G protein-coupled receptor G3
117
0.94
chr8_40331087_40331414 0.90 Fgf20
fibroblast growth factor 20
22919
0.16
chr9_25483006_25483630 0.90 Eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
451
0.84
chr4_148591515_148592619 0.89 Srm
spermidine synthase
149
0.91
chr8_126978786_126979425 0.89 Gm38574
predicted gene, 38574
3127
0.19
chrX_13070376_13070983 0.88 Usp9x
ubiquitin specific peptidase 9, X chromosome
819
0.63
chr6_37732562_37732714 0.87 Ybx1-ps2
Y box protein 1, pseudogene 2
45443
0.16
chr8_70489289_70489965 0.87 1700020G03Rik
RIKEN cDNA 1700020G03 gene
1446
0.19
chr2_46443289_46444038 0.86 Gm13470
predicted gene 13470
953
0.67
chr4_15268528_15269161 0.86 Tmem64
transmembrane protein 64
3013
0.35
chr8_122230916_122231166 0.85 Zfp469
zinc finger protein 469
27579
0.16
chr6_53337522_53338047 0.85 Creb5
cAMP responsive element binding protein 5
26913
0.22
chr7_80680164_80680452 0.84 Crtc3
CREB regulated transcription coactivator 3
8569
0.17
chr7_97453001_97454277 0.84 Kctd14
potassium channel tetramerisation domain containing 14
417
0.79
chr1_71648830_71648981 0.83 Apol7d
apolipoprotein L 7d
3932
0.21
chr7_127912328_127912485 0.82 Kat8
K(lysine) acetyltransferase 8
110
0.89
chr15_78844291_78845201 0.81 Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
2122
0.16
chr1_131126459_131126729 0.81 Dyrk3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
11651
0.13
chr5_120015655_120015806 0.80 n-R5s176
nuclear encoded rRNA 5S 176
48605
0.12
chr12_98215602_98215753 0.80 Galc
galactosylceramidase
851
0.61
chr4_120161120_120162185 0.79 Edn2
endothelin 2
446
0.87
chr1_193157193_193157397 0.79 Irf6
interferon regulatory factor 6
626
0.59
chr2_167690537_167691384 0.79 A530013C23Rik
RIKEN cDNA A530013C23 gene
217
0.84
chr18_46615305_46615565 0.78 Gm3734
predicted gene 3734
15372
0.13
chr2_131235468_131235658 0.78 Mavs
mitochondrial antiviral signaling protein
1458
0.27
chr6_83004488_83004730 0.77 Gm43981
predicted gene, 43981
12964
0.07
chr4_150132731_150133360 0.77 Slc2a5
solute carrier family 2 (facilitated glucose transporter), member 5
4099
0.14
chr2_32317910_32318744 0.77 Gm23363
predicted gene, 23363
62
0.57
chr14_40960480_40960700 0.77 Tspan14
tetraspanin 14
6217
0.2
chr1_164418317_164418468 0.77 Gm37411
predicted gene, 37411
6321
0.17
chr11_116782685_116783105 0.76 St6galnac1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
7388
0.12
chrX_100493655_100494126 0.76 Igbp1
immunoglobulin (CD79A) binding protein 1
401
0.82
chr11_60353035_60353731 0.76 Drc3
dynein regulatory complex subunit 3
3
0.89
chr6_24530292_24531109 0.75 Asb15
ankyrin repeat and SOCS box-containing 15
2556
0.22
chr8_122550130_122550538 0.74 Piezo1
piezo-type mechanosensitive ion channel component 1
995
0.35
chr18_70628505_70628656 0.74 Mbd2
methyl-CpG binding domain protein 2
10807
0.19
chr14_65832277_65832465 0.74 Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
552
0.75
chr19_45843682_45843904 0.73 Gm50196
predicted gene, 50196
176
0.94
chr1_36921949_36922257 0.73 F830112A20Rik
RIKEN cDNA F830112A20 gene
4245
0.16
chr19_8966323_8966828 0.72 Eef1g
eukaryotic translation elongation factor 1 gamma
466
0.59
chr2_34646436_34646901 0.72 Gm13414
predicted gene 13414
3572
0.22
chr11_94226213_94226416 0.72 Tob1
transducer of ErbB-2.1
14860
0.16
chr3_21936227_21936704 0.72 Gm43674
predicted gene 43674
62003
0.12
chr15_59204218_59204369 0.72 Rpl7-ps8
ribosomal protein L7, pseudogene 8
6615
0.21
chr12_76447781_76448313 0.72 Gm10451
predicted gene 10451
1651
0.25
chr11_51584817_51585581 0.71 Phykpl
5-phosphohydroxy-L-lysine phospholyase
388
0.8
chrX_95967402_95968736 0.71 Las1l
LAS1-like (S. cerevisiae)
11107
0.24
chrX_20819076_20820391 0.70 Gm24824
predicted gene, 24824
4081
0.13
chr11_96943491_96943971 0.70 Pnpo
pyridoxine 5'-phosphate oxidase
48
0.85
chr15_89765445_89765717 0.69 Gm18476
predicted gene, 18476
29064
0.19
chr7_16784339_16784989 0.69 Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
74
0.95
chr11_30471500_30471889 0.69 4930505A04Rik
RIKEN cDNA 4930505A04 gene
114
0.97
chr7_111122900_111123245 0.68 1700012D14Rik
RIKEN cDNA 1700012D14 gene
388
0.82
chr10_59150061_59150340 0.68 Septin10
septin 10
28657
0.16
chr14_69554959_69555320 0.68 Gm27174
predicted gene 27174
193
0.59
chr4_104766381_104766876 0.68 C8b
complement component 8, beta polypeptide
233
0.96
chr11_113148101_113148330 0.68 2610035D17Rik
RIKEN cDNA 2610035D17 gene
24862
0.24
chr6_34317495_34318174 0.68 Akr1b3
aldo-keto reductase family 1, member B3 (aldose reductase)
356
0.85
chr11_60931035_60931321 0.67 Map2k3os
mitogen-activated protein kinase kinase 3, opposite strand
689
0.44
chr17_81723922_81724212 0.67 Slc8a1
solute carrier family 8 (sodium/calcium exchanger), member 1
14310
0.27
chr11_35838085_35838789 0.67 Rars
arginyl-tRNA synthetase
3931
0.2
chr8_116945233_116945384 0.67 Atmin
ATM interactor
1915
0.27
chr11_115974294_115975742 0.67 Itgb4
integrin beta 4
39
0.95
chr14_69336710_69337073 0.67 Gm16677
predicted gene, 16677
191
0.59
chr2_162908186_162908529 0.67 Gm11452
predicted gene 11452
433
0.76
chr8_47350098_47350393 0.67 Stox2
storkhead box 2
2103
0.39
chr14_118162936_118163114 0.66 Gpr180
G protein-coupled receptor 180
25867
0.13
chr17_35200817_35202291 0.66 Tnf
tumor necrosis factor
450
0.46
chr19_41837789_41838110 0.65 Frat1
frequently rearranged in advanced T cell lymphomas
7979
0.14
chr7_103840298_103840449 0.65 Hbb-bh2
hemoglobin beta, bh2
147
0.86
chr5_21672920_21673694 0.64 Gm15719
predicted gene 15719
16234
0.12
chr15_40167052_40167633 0.64 Gm33301
predicted gene, 33301
4735
0.21
chrX_134612012_134613237 0.64 Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
11338
0.1
chr4_89303654_89303949 0.63 Cdkn2b
cyclin dependent kinase inhibitor 2B
7238
0.16
chr15_67177033_67177622 0.63 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
497
0.86
chr13_48273486_48273892 0.63 A330048O09Rik
RIKEN cDNA A330048O09 gene
195
0.92
chr14_75179791_75179942 0.63 Lcp1
lymphocyte cytosolic protein 1
3658
0.19
chr17_94749332_94750021 0.62 Mettl4
methyltransferase like 4
216
0.68
chr6_4509490_4509713 0.61 Gm43921
predicted gene, 43921
3514
0.18
chr1_185515159_185516225 0.60 5033404E19Rik
RIKEN cDNA 5033404E19 gene
18304
0.17
chr3_60472420_60472995 0.60 Mbnl1
muscleblind like splicing factor 1
123
0.98
chr3_135402193_135402447 0.60 Slc9b1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
8316
0.12
chr3_42214739_42214890 0.60 Gm37846
predicted gene, 37846
50949
0.18
chr10_117417779_117419012 0.60 Gm40770
predicted gene, 40770
4491
0.16
chr18_20944519_20944761 0.60 Rnf125
ring finger protein 125
15
0.98
chr13_100730197_100730936 0.59 Cdk7
cyclin-dependent kinase 7
334
0.82
chr2_181864457_181865175 0.59 Polr3k
polymerase (RNA) III (DNA directed) polypeptide K
456
0.79
chr6_29388244_29389129 0.59 Opn1sw
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
218
0.87
chr13_54384778_54385063 0.58 Cplx2
complexin 2
13571
0.15
chr19_34922405_34923100 0.58 Kif20b
kinesin family member 20B
318
0.89
chr1_160044056_160045077 0.58 4930523C07Rik
RIKEN cDNA 4930523C07 gene
119
0.66
chr19_53424479_53425164 0.58 Mirt1
myocardial infarction associated transcript 1
26670
0.1
chr2_26576650_26576878 0.58 Egfl7
EGF-like domain 7
3250
0.12
chr2_76969596_76969826 0.58 Ttn
titin
10471
0.25
chr7_123462181_123462933 0.58 Aqp8
aquaporin 8
245
0.93
chr8_105254282_105255162 0.57 B3gnt9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
429
0.6
chr17_73109554_73109705 0.57 Lclat1
lysocardiolipin acyltransferase 1
1635
0.44
chr13_5864772_5865145 0.57 Klf6
Kruppel-like factor 6
280
0.89
chr7_142386214_142386365 0.57 Ctsd
cathepsin D
1530
0.23
chr10_117106318_117106593 0.57 Frs2
fibroblast growth factor receptor substrate 2
24391
0.12
chr8_26258566_26258717 0.57 Gm31727
predicted gene, 31727
8336
0.13
chr11_94933619_94934699 0.57 Col1a1
collagen, type I, alpha 1
2065
0.21
chr2_93460789_93461036 0.57 Cd82
CD82 antigen
1000
0.52
chr17_87106697_87107199 0.56 Socs5
suppressor of cytokine signaling 5
731
0.62
chr15_41868535_41869588 0.56 Abra
actin-binding Rho activating protein
659
0.72
chr8_127499907_127500504 0.56 Pard3
par-3 family cell polarity regulator
52459
0.15
chr10_42274070_42274388 0.56 Foxo3
forkhead box O3
2467
0.36
chr14_60172191_60172498 0.56 Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
5195
0.16
chr13_47516771_47516922 0.56 4930471G24Rik
RIKEN cDNA 4930471G24 gene
150704
0.04
chr3_53463770_53464057 0.56 Proser1
proline and serine rich 1
19
0.91
chr6_128438803_128439200 0.56 Gm10069
predicted gene 10069
244
0.54
chr7_12927508_12929010 0.56 Rnf225
ring finger protein 225
843
0.35
chr9_67832082_67832627 0.55 C2cd4a
C2 calcium-dependent domain containing 4A
24
0.98
chr2_153778694_153779749 0.55 Efcab8
EF-hand calcium binding domain 8
710
0.64
chrX_8271051_8272966 0.55 Slc38a5
solute carrier family 38, member 5
366
0.82
chr18_61665569_61665720 0.54 Carmn
cardiac mesoderm enhancer-associated non-coding RNA
107
0.94
chr7_19755645_19756922 0.54 Bcam
basal cell adhesion molecule
668
0.44
chr17_46083992_46084836 0.54 Gm36200
predicted gene, 36200
148
0.93
chr2_115581707_115582141 0.54 BC052040
cDNA sequence BC052040
123
0.79
chr14_63123716_63123867 0.54 Ctsb
cathepsin B
1277
0.35
chr3_121170933_121171677 0.54 Rwdd3
RWD domain containing 3
383
0.81
chr2_44512453_44512604 0.54 Gtdc1
glycosyltransferase-like domain containing 1
58819
0.15
chr11_3123510_3123960 0.54 Pisd-ps1
phosphatidylserine decarboxylase, pseudogene 1
2169
0.23
chr11_69546279_69547462 0.54 Dnah2
dynein, axonemal, heavy chain 2
2238
0.14
chr7_103875074_103875225 0.54 Olfr66
olfactory receptor 66
7092
0.06
chr19_53680794_53681963 0.53 Rbm20
RNA binding motif protein 20
4072
0.23
chr11_117072335_117072496 0.53 Snhg20
small nucleolar RNA host gene 20
3593
0.12
chr10_67297290_67297848 0.53 Gm49454
predicted gene, 49454
163
0.95
chr7_80386817_80388333 0.53 Fes
feline sarcoma oncogene
156
0.91
chr3_96697167_96697666 0.53 Pias3
protein inhibitor of activated STAT 3
222
0.83
chr10_120421952_120422678 0.53 Mir763
microRNA 763
25795
0.15
chr4_34337418_34338131 0.53 Gm12751
predicted gene 12751
16269
0.2
chr11_94937274_94938132 0.52 Col1a1
collagen, type I, alpha 1
17
0.96
chr15_103274021_103274174 0.52 Copz1
coatomer protein complex, subunit zeta 1
1185
0.3
chr1_183344281_183344447 0.52 Mia3
melanoma inhibitory activity 3
932
0.48
chr1_34439512_34439753 0.52 Ccdc115
coiled-coil domain containing 115
40
0.71
chr13_90089026_90089475 0.52 Tmem167
transmembrane protein 167
127
0.56
chr12_78904719_78905643 0.52 Plek2
pleckstrin 2
1783
0.34
chr5_129503974_129504125 0.51 Sfswap
splicing factor SWAP
75
0.97
chr9_69457683_69458529 0.51 Mir3109
microRNA 3109
1162
0.34
chr14_45878534_45878807 0.51 Gm8317
predicted gene 8317
20124
0.16
chr4_59003161_59004289 0.51 Gm20503
predicted gene 20503
515
0.44
chr10_80172517_80173175 0.50 Fam174c
family with sequence similarity 174, member C
98
0.89
chr16_39056794_39057463 0.50 Gm22500
predicted gene, 22500
129919
0.05
chr16_22548276_22549083 0.50 Gm15651
predicted gene 15651
126
0.94
chr15_78598536_78598827 0.50 Cyth4
cytohesin 4
1532
0.27
chr11_3335655_3335969 0.50 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
1431
0.26
chr15_101145160_101146434 0.50 Acvrl1
activin A receptor, type II-like 1
8197
0.11
chr8_84810943_84811513 0.50 Nfix
nuclear factor I/X
10884
0.08
chr12_25097278_25099364 0.50 Id2
inhibitor of DNA binding 2
1181
0.44

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Creb3l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3 1.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 1.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.3 0.9 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3 0.8 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3 0.8 GO:0001543 ovarian follicle rupture(GO:0001543)
0.3 1.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 0.7 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 0.7 GO:0006059 hexitol metabolic process(GO:0006059)
0.2 0.8 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.2 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.7 GO:0061450 trophoblast cell migration(GO:0061450)
0.2 0.5 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 0.9 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.4 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.3 GO:1904833 positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.1 0.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 1.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.5 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.1 0.6 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.3 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.4 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.1 0.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.4 GO:0003166 bundle of His development(GO:0003166)
0.1 0.4 GO:0097460 ferrous iron import into cell(GO:0097460)
0.1 0.5 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.1 0.5 GO:1904683 regulation of metalloendopeptidase activity(GO:1904683)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.3 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.2 GO:0033505 floor plate morphogenesis(GO:0033505)
0.1 0.6 GO:0015825 L-serine transport(GO:0015825)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.3 GO:0038044 transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0051031 tRNA transport(GO:0051031)
0.1 0.3 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.4 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.1 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.7 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.2 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 1.6 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.3 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.1 0.1 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.1 0.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.2 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.1 1.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.2 GO:0003175 tricuspid valve development(GO:0003175)
0.1 0.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.8 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.2 GO:0043174 nucleoside salvage(GO:0043174)
0.1 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.2 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.1 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.1 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 0.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.2 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0 0.3 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 1.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.1 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 1.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.1 GO:0072530 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.1 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.0 1.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0 0.6 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:0040031 snRNA modification(GO:0040031)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0001842 neural fold formation(GO:0001842)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0048371 lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.8 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.1 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.4 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.2 GO:0033866 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:1900084 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.0 GO:1902302 regulation of potassium ion export(GO:1902302)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.5 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.0 GO:0032202 telomere assembly(GO:0032202)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:1903748 negative regulation of protein targeting to mitochondrion(GO:1903215) negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0010912 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.3 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.0 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.0 GO:1902750 negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0071236 cellular response to antibiotic(GO:0071236)
0.0 0.0 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.1 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.0 GO:0001555 oocyte growth(GO:0001555)
0.0 0.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.0 GO:1904193 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0 0.0 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.0 GO:0009445 putrescine metabolic process(GO:0009445)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.0 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0071435 potassium ion export(GO:0071435)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0070488 neutrophil aggregation(GO:0070488)
0.0 0.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0 0.0 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.1 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.0 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.0 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.0 GO:0061620 glycolytic process through glucose-6-phosphate(GO:0061620)
0.0 0.0 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.0 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:0098910 regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0032438 melanosome organization(GO:0032438)
0.0 0.4 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.0 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.0 GO:0048818 positive regulation of hair follicle maturation(GO:0048818)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0031269 pseudopodium assembly(GO:0031269)
0.0 0.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.0 0.0 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.0 GO:0016093 polyprenol metabolic process(GO:0016093)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:1904526 regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0 0.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.2 GO:0000154 rRNA modification(GO:0000154)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.0 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.0 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.0 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.0 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.0 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.0 GO:0010513 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.0 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0006348 chromatin silencing at telomere(GO:0006348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 0.7 GO:0072487 MSL complex(GO:0072487)
0.2 0.5 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.5 GO:0071546 pi-body(GO:0071546)
0.1 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0038201 TOR complex(GO:0038201)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.3 GO:0033646 host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0097443 sorting endosome(GO:0097443)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.0 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 3.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.0 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.0 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 1.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 1.0 GO:0030984 kininogen binding(GO:0030984)
0.2 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.6 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0004096 catalase activity(GO:0004096)
0.1 3.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.8 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.2 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.1 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.5 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.1 GO:0008905 mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 0.3 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.1 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.7 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.0 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0015254 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 1.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0038100 nodal binding(GO:0038100)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0008969 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) inositol-4,5-bisphosphate 5-phosphatase activity(GO:0030487) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.0 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0034889 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.8 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0070061 fructose binding(GO:0070061)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.1 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.0 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 4.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME ADAPTIVE IMMUNE SYSTEM Genes involved in Adaptive Immune System
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.0 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.0 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation