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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Crem_Jdp2

Z-value: 0.66

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Transcription factors associated with Crem_Jdp2

Gene Symbol	Gene ID	Gene Info
Crem Ensembl NCBI MGI UniProt	ENSMUSG00000063889.10	Crem
Jdp2 Ensembl NCBI MGI UniProt	ENSMUSG00000034271.9	Jdp2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Crem	chr18_3281982_3282133	288	0.922724	-0.40	1.6e-03	Click!
Crem	chr18_3280402_3280691	532	0.811910	-0.31	1.8e-02	Click!
Crem	chr18_3281576_3281910	4	0.982127	-0.25	5.3e-02	Click!
Crem	chr18_3274616_3274842	6349	0.234001	0.12	3.5e-01	Click!
Crem	chr18_3280827_3281518	40	0.980926	-0.12	3.5e-01	Click!
Jdp2	chr12_85601303_85602833	154	0.942518	-0.48	1.0e-04	Click!
Jdp2	chr12_85581045_85581885	17562	0.146422	0.34	7.4e-03	Click!
Jdp2	chr12_85603052_85603203	905	0.524648	-0.33	9.3e-03	Click!
Jdp2	chr12_85603259_85603447	1131	0.437931	-0.20	1.2e-01	Click!
Jdp2	chr12_85571980_85572497	26789	0.130692	0.16	2.2e-01	Click!

Activity of the Crem_Jdp2 motif across conditions

Conditions sorted by the z-value of the Crem_Jdp2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_79498955_79500626	3.57	Mir9-3hg	Mir9-3 host gene	236	0.84
chr1_79439702_79440415	3.24	Scg2	secretogranin II	16	0.98
chr18_35214570_35215443	2.56	Lrrtm2	leucine rich repeat transmembrane neuronal 2	2	0.52
chr7_16982884_16983633	2.40	Gm42372	predicted gene, 42372	172	0.9
chr11_115511512_115512231	2.30	Jpt1	Jupiter microtubule associated homolog 1	2245	0.14
chr15_84104886_84106159	2.27	Sult4a1	sulfotransferase family 4A, member 1	87	0.93
chr2_178141581_178143125	2.16	Phactr3	phosphatase and actin regulator 3	420	0.88
chr3_17793835_17795104	2.08	Mir124-2hg	Mir124-2 host gene (non-protein coding)	427	0.75
chr5_116589538_116590511	2.01	Srrm4	serine/arginine repetitive matrix 4	1793	0.34
chr17_31809980_31810371	1.93	Gm49999	predicted gene, 49999	20649	0.15
chr10_41072016_41072570	1.93	Gpr6	G protein-coupled receptor 6	8	0.97
chrX_73063945_73064811	1.87	Pnma3	paraneoplastic antigen MA3	409	0.71
chr5_117241784_117242411	1.83	Taok3	TAO kinase 3	1637	0.3
chr11_6604576_6606131	1.81	Nacad	NAC alpha domain containing	700	0.46
chr8_87539918_87540560	1.75	4933402J07Rik	RIKEN cDNA 4933402J07 gene	23614	0.14
chr2_105668422_105670370	1.73	Pax6	paired box 6	461	0.65
chr4_150651111_150652374	1.71	Slc45a1	solute carrier family 45, member 1	355	0.88
chr9_91350199_91351559	1.70	A730094K22Rik	RIKEN cDNA A730094K22 gene	74	0.95
chr8_65617917_65619195	1.62	Marchf1	membrane associated ring-CH-type finger 1	31	0.99
chr5_122636955_122637295	1.51	P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	6786	0.14
chr5_104109155_104109917	1.48	Gm26703	predicted gene, 26703	245	0.88
chr1_153660970_153662018	1.47	Rgs8	regulator of G-protein signaling 8	413	0.8
chr15_25758674_25760120	1.45	Myo10	myosin X	612	0.78
chr18_76855816_76857376	1.40	Skor2	SKI family transcriptional corepressor 2	191	0.96
chr3_34656299_34657721	1.39	Sox2ot	SOX2 overlapping transcript (non-protein coding)	974	0.4
chr3_88214322_88216234	1.38	Mir3093	microRNA 3093	107	0.63
chr12_111671006_111672264	1.38	Ckb	creatine kinase, brain	91	0.94
chr13_83737592_83739114	1.36	Gm33366	predicted gene, 33366	182	0.66
chr19_5084688_5085540	1.32	Tmem151a	transmembrane protein 151A	233	0.79
chr18_28077967_28078215	1.29	Gm5064	predicted gene 5064	110726	0.07
chr2_105673131_105674553	1.29	Pax6	paired box 6	121	0.95
chr12_68997254_68997526	1.27	Gm47515	predicted gene, 47515	2420	0.27
chr6_17748935_17749179	1.26	St7	suppression of tumorigenicity 7	113	0.56
chr5_35454181_35454829	1.25	Gm43377	predicted gene 43377	58407	0.08
chr10_25458395_25459149	1.24	Epb41l2	erythrocyte membrane protein band 4.1 like 2	8201	0.21
chr2_94246278_94247531	1.20	Mir670hg	MIR670 host gene (non-protein coding)	3566	0.17
chr3_94478073_94479450	1.20	Celf3	CUGBP, Elav-like family member 3	70	0.92
chr15_98983254_98984205	1.19	4930578M01Rik	RIKEN cDNA 4930578M01 gene	102	0.93
chr4_149854254_149854922	1.17	Gm47301	predicted gene, 47301	36824	0.09
chr17_78454131_78454627	1.14	Gm19399	predicted gene, 19399	4266	0.19
chr16_42444471_42445397	1.14	Gap43	growth associated protein 43	104283	0.07
chr3_88831100_88832914	1.12	1500004A13Rik	RIKEN cDNA 1500004A13 gene	361	0.77
chr8_12917045_12917331	1.12	Mcf2l	mcf.2 transforming sequence-like	1213	0.28
chr7_79504311_79505700	1.12	Mir9-3	microRNA 9-3	259	0.82
chr19_61226246_61226725	1.11	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	198	0.91
chr17_56137995_56139079	1.09	Sema6b	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	1806	0.18
chr3_88771097_88772528	1.08	Syt11	synaptotagmin XI	787	0.45
chr12_102554749_102554936	1.05	Chga	chromogranin A	127	0.96
chr15_64922842_64923330	1.04	Adcy8	adenylate cyclase 8	790	0.73
chr17_43952337_43954220	1.04	Rcan2	regulator of calcineurin 2	27	0.99
chr18_31443497_31444446	1.03	Syt4	synaptotagmin IV	3435	0.19
chrX_66652653_66653969	0.99	Slitrk2	SLIT and NTRK-like family, member 2	304	0.9
chr3_95224335_95224907	0.98	Mllt11	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11	4056	0.09
chr2_132781102_132782201	0.94	Chgb	chromogranin B	373	0.82
chr6_83185720_83187846	0.92	Dctn1	dynactin 1	837	0.39
chr8_54957303_54957776	0.91	Gm45263	predicted gene 45263	2280	0.24
chr7_37768541_37768692	0.89	Zfp536	zinc finger protein 536	1008	0.62
chr18_82825279_82826286	0.86	4930445N18Rik	RIKEN cDNA 4930445N18 gene	30112	0.12
chr3_94483546_94484940	0.86	Celf3	CUGBP, Elav-like family member 3	84	0.93
chr15_83509799_83509950	0.85	Ttll1	tubulin tyrosine ligase-like 1	919	0.44
chr8_54956010_54956394	0.83	Gpm6a	glycoprotein m6a	1359	0.38
chr15_69041723_69041971	0.82	Gm49422	predicted gene, 49422	82316	0.1
chr8_70486586_70487634	0.82	Tmem59l	transmembrane protein 59-like	214	0.81
chr9_87115556_87115707	0.82	Gm8282	predicted gene 8282	11703	0.17
chr6_13837081_13837232	0.82	Gpr85	G protein-coupled receptor 85	85	0.97
chr15_28181738_28182178	0.81	Gm49234	predicted gene, 49234	10164	0.17
chr7_109780891_109781950	0.79	Nrip3	nuclear receptor interacting protein 3	123	0.94
chr12_31711352_31711698	0.79	Gpr22	G protein-coupled receptor 22	2401	0.25
chr6_124463804_124465512	0.78	Clstn3	calsyntenin 3	136	0.92
chrX_153035799_153036204	0.77	Mageh1	melanoma antigen, family H, 1	1574	0.28
chr1_79437543_79437779	0.77	Scg2	secretogranin II	2381	0.37
chr4_109976788_109977122	0.76	Dmrta2os	doublesex and mab-3 related transcription factor like family A2, opposite strand	536	0.69
chr5_150906399_150906670	0.75	Gm43298	predicted gene 43298	23892	0.17
chr7_63445472_63445728	0.75	Otud7a	OTU domain containing 7A	823	0.5
chr5_150262108_150262988	0.74	Fry	FRY microtubule binding protein	2781	0.26
chr19_61225550_61226044	0.74	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	307	0.84
chr7_126949305_126949933	0.72	Asphd1	aspartate beta-hydroxylase domain containing 1	37	0.9
chr5_39641102_39641253	0.71	Hs3st1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	3420	0.26
chr9_58008709_58009443	0.71	Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	2665	0.19
chr9_40268795_40270233	0.71	Scn3b	sodium channel, voltage-gated, type III, beta	81	0.96
chr13_23761268_23761510	0.71	H4c1	H4 clustered histone 1	159	0.77
chr13_78181011_78182180	0.71	Gm38604	predicted gene, 38604	1564	0.29
chr18_86473556_86473849	0.70	Gm50384	predicted gene, 50384	227	0.95
chr7_62417581_62417734	0.70	Mkrn3	makorin, ring finger protein, 3	2482	0.24
chr5_129225715_129226283	0.70	Rps16-ps2	ribosomal protein S16, pseudogene 2	97482	0.07
chrX_143664015_143665455	0.69	Pak3	p21 (RAC1) activated kinase 3	156	0.98
chr1_134079290_134079527	0.69	Btg2	BTG anti-proliferation factor 2	288	0.86
chr3_3308823_3309359	0.68	Gm8747	predicted gene 8747	42064	0.2
chr9_121403057_121404479	0.67	Trak1	trafficking protein, kinesin binding 1	290	0.91
chr16_29837120_29837709	0.66	Gm32679	predicted gene, 32679	2686	0.29
chr6_83038262_83039190	0.66	Loxl3	lysyl oxidase-like 3	326	0.68
chr7_19932934_19933834	0.66	Igsf23	immunoglobulin superfamily, member 23	11514	0.07
chr1_118434945_118435685	0.66	Clasp1	CLIP associating protein 1	15591	0.13
chr17_24689022_24690262	0.65	Syngr3	synaptogyrin 3	313	0.69
chr13_65258047_65259444	0.65	Gm10775	predicted gene 10775	794	0.38
chr7_78882466_78883900	0.65	Mir7-2	microRNA 7-2	5094	0.13
chr12_47164059_47165060	0.64	Gm36971	predicted gene, 36971	483	0.87
chr13_48227672_48228587	0.64	Gm36346	predicted gene, 36346	9122	0.16
chr15_84167436_84168909	0.63	Mir6392	microRNA 6392	98	0.77
chr5_134102760_134102911	0.63	Castor2	cytosolic arginine sensor for mTORC1 subunit 2	2830	0.2
chr12_103315511_103316208	0.63	Fam181a	family with sequence similarity 181, member A	900	0.36
chr9_73967774_73969221	0.63	Unc13c	unc-13 homolog C	469	0.88
chr1_132322108_132322259	0.63	Nuak2	NUAK family, SNF1-like kinase, 2	5413	0.13
chr18_37800729_37801183	0.62	Pcdhgc3	protocadherin gamma subfamily C, 3	5408	0.06
chr3_89959021_89959708	0.62	Atp8b2	ATPase, class I, type 8B, member 2	190	0.88
chr12_52009968_52010722	0.62	Dtd2	D-tyrosyl-tRNA deacylase 2	3844	0.19
chr8_61227862_61229170	0.62	Sh3rf1	SH3 domain containing ring finger 1	4272	0.23
chr14_52313293_52314443	0.62	Sall2	spalt like transcription factor 2	2455	0.13
chr2_127520770_127522413	0.61	Kcnip3	Kv channel interacting protein 3, calsenilin	221	0.89
chr11_84042912_84043451	0.59	Synrg	synergin, gamma	16526	0.16
chr9_119322832_119323536	0.59	Oxsr1	oxidative-stress responsive 1	757	0.52
chr11_102466964_102467996	0.59	Itga2b	integrin alpha 2b	281	0.83
chr7_121391567_121393161	0.58	Hs3st2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	74	0.93
chr4_155344717_155346023	0.58	Prkcz	protein kinase C, zeta	12	0.96
chr1_92522550_92522701	0.58	Olfr1414	olfactory receptor 1414	3964	0.13
chr15_38373513_38374380	0.58	Gm41307	predicted gene, 41307	30208	0.13
chrX_136290697_136291204	0.58	n-R5s12	nuclear encoded rRNA 5S 12	13445	0.09
chr9_110051810_110053856	0.57	Map4	microtubule-associated protein 4	781	0.54
chr2_25264308_25268001	0.56	Tprn	taperin	1410	0.14
chr1_188714025_188714176	0.56	Gm25269	predicted gene, 25269	46376	0.18
chr3_129536277_129537008	0.56	Gm43072	predicted gene 43072	1499	0.33
chrX_170674573_170675954	0.55	Asmt	acetylserotonin O-methyltransferase	2619	0.41
chr16_4790080_4790632	0.55	Cdip1	cell death inducing Trp53 target 1	64	0.96
chr10_21144738_21145721	0.55	Gm26577	predicted gene, 26577	135	0.93
chr2_116053626_116054503	0.55	Meis2	Meis homeobox 2	4384	0.2
chr5_139324497_139325782	0.55	Adap1	ArfGAP with dual PH domains 1	483	0.72
chr9_20976801_20976984	0.54	S1pr2	sphingosine-1-phosphate receptor 2	111	0.92
chr5_134675713_134676967	0.54	Gm10369	predicted gene 10369	150	0.92
chr12_4082205_4082840	0.53	Dnajc27	DnaJ heat shock protein family (Hsp40) member C27	61	0.97
chr10_34316245_34317506	0.53	Nt5dc1	5'-nucleotidase domain containing 1	3192	0.16
chr19_53340390_53340659	0.52	Mxi1	MAX interactor 1, dimerization protein	10116	0.13
chr2_147968209_147968363	0.52	9030622O22Rik	RIKEN cDNA 9030622O22 gene	7899	0.24
chr6_142960447_142960598	0.51	St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	3619	0.18
chr1_37299560_37299784	0.51	1700074A21Rik	RIKEN cDNA 1700074A21 gene	25	0.71
chr9_112227323_112228073	0.50	2310075C17Rik	RIKEN cDNA 2310075C17 gene	119	0.96
chr5_32713090_32713944	0.50	Gm43852	predicted gene 43852	471	0.7
chr8_105606313_105606835	0.50	Ripor1	RHO family interacting cell polarization regulator 1	1319	0.23
chr8_69625128_69625279	0.50	Zfp868	zinc finger protein 868	342	0.85
chr10_128378554_128378705	0.49	Gm26308	predicted gene, 26308	730	0.32
chr6_17583744_17584496	0.49	Met	met proto-oncogene	37147	0.15
chr15_77245294_77246216	0.49	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	169	0.94
chr8_69749413_69749661	0.48	Zfp963	zinc finger protein 963	425	0.75
chr4_155893812_155895517	0.48	Acap3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	2352	0.11
chr8_70743042_70744602	0.48	Pde4c	phosphodiesterase 4C, cAMP specific	743	0.38
chr15_78509793_78510375	0.47	Il2rb	interleukin 2 receptor, beta chain	14813	0.09
chr1_165091570_165092283	0.47	4930568G15Rik	RIKEN cDNA 4930568G15 gene	2	0.98
chr9_113811975_113812935	0.47	Clasp2	CLIP associating protein 2	131	0.97
chr12_82469855_82470833	0.47	Gm5435	predicted gene 5435	26193	0.18
chr18_31316134_31317386	0.47	Rit2	Ras-like without CAAX 2	351	0.9
chr2_180892979_180894605	0.47	Mir124a-3	microRNA 124a-3	248	0.53
chr2_118662893_118663233	0.46	Pak6	p21 (RAC1) activated kinase 6	240	0.9
chr15_72806569_72807700	0.46	Peg13	paternally expressed 13	3190	0.32
chr3_4798346_4798833	0.46	1110015O18Rik	RIKEN cDNA 1110015O18 gene	119	0.97
chr3_132880896_132881303	0.45	Gm29811	predicted gene, 29811	2503	0.24
chr11_94043944_94044915	0.45	Spag9	sperm associated antigen 9	64	0.97
chr6_91838887_91839258	0.45	Grip2	glutamate receptor interacting protein 2	11822	0.16
chr19_25622238_25623053	0.44	Dmrt3	doublesex and mab-3 related transcription factor 3	12108	0.21
chr16_90709814_90710620	0.44	Mis18a	MIS18 kinetochore protein A	16922	0.13
chr19_6501022_6501221	0.44	Nrxn2	neurexin II	3286	0.16
chr16_92340779_92341614	0.44	Smim34	small integral membrane protein 34	11942	0.11
chr16_87128194_87128870	0.44	Gm32865	predicted gene, 32865	93	0.98
chr13_100892366_100893024	0.44	Gm41041	predicted gene, 41041	17194	0.14
chr15_91017138_91018295	0.44	Kif21a	kinesin family member 21A	32102	0.16
chr12_24829454_24829782	0.44	Mboat2	membrane bound O-acyltransferase domain containing 2	1261	0.32
chr7_4149072_4149804	0.44	Leng9	leukocyte receptor cluster (LRC) member 9	936	0.34
chr4_127549306_127549951	0.43	A630031M04Rik	RIKEN cDNA A630031M04 gene	4527	0.31
chr7_118583609_118584872	0.43	Tmc7	transmembrane channel-like gene family 7	446	0.77
chr18_6512631_6512915	0.43	Epc1	enhancer of polycomb homolog 1	3335	0.21
chr5_147399872_147401256	0.42	Flt3	FMS-like tyrosine kinase 3	75	0.91
chr3_116222523_116223160	0.42	Gm31651	predicted gene, 31651	22433	0.15
chr1_165999821_165999972	0.42	Pou2f1	POU domain, class 2, transcription factor 1	2713	0.21
chr1_6734529_6735444	0.42	St18	suppression of tumorigenicity 18	116	0.98
chr17_90451511_90451662	0.42	Nrxn1	neurexin I	3236	0.28
chr9_57467083_57468096	0.42	Scamp5	secretory carrier membrane protein 5	406	0.73
chr13_99493038_99493247	0.42	5330431K02Rik	RIKEN cDNA 5330431K02 gene	11297	0.16
chr5_25222603_25223750	0.42	E130116L18Rik	RIKEN cDNA E130116L18 gene	23	0.81
chr11_114793777_114794456	0.41	Btbd17	BTB (POZ) domain containing 17	1757	0.26
chr7_48963141_48964311	0.41	Nav2	neuron navigator 2	4629	0.19
chr8_31113321_31113667	0.41	Rnf122	ring finger protein 122	1630	0.32
chr2_19909579_19910504	0.41	Etl4	enhancer trap locus 4	261	0.91
chr10_80300884_80302968	0.41	Apc2	APC regulator of WNT signaling pathway 2	106	0.9
chr9_108824114_108825614	0.41	Gm35025	predicted gene, 35025	3	0.87
chr5_69341722_69341873	0.41	Kctd8	potassium channel tetramerisation domain containing 8	118	0.92
chr14_55560478_55560708	0.41	Dcaf11	DDB1 and CUL4 associated factor 11	59	0.64
chr9_45054509_45055372	0.40	Mpzl3	myelin protein zero-like 3	246	0.61
chr9_108787261_108787546	0.40	Ip6k2	inositol hexaphosphate kinase 2	3538	0.12
chr13_20939238_20939491	0.40	Aoah	acyloxyacyl hydrolase	71269	0.09
chr10_115586791_115588064	0.40	Lgr5	leucine rich repeat containing G protein coupled receptor 5	66	0.97
chr9_4793004_4793465	0.40	Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	2285	0.46
chr18_83192582_83193531	0.40	1700095A13Rik	RIKEN cDNA 1700095A13 gene	85166	0.08
chr6_28980713_28981850	0.40	Gm3294	predicted gene 3294	353	0.88
chr13_44329334_44329485	0.39	Gm29676	predicted gene, 29676	48960	0.12
chr6_127119580_127119731	0.39	Gm43126	predicted gene 43126	3311	0.14
chr4_41568273_41569615	0.39	Fam219a	family with sequence similarity 219, member A	565	0.5
chr15_81926465_81926674	0.39	Polr3h	polymerase (RNA) III (DNA directed) polypeptide H	329	0.77
chr16_16828695_16829635	0.38	Spag6l	sperm associated antigen 6-like	116	0.93
chr8_123410787_123412789	0.38	Tubb3	tubulin, beta 3 class III	198	0.84
chr11_52764429_52765649	0.38	Fstl4	follistatin-like 4	405	0.91
chr15_81936444_81938042	0.38	Csdc2	cold shock domain containing C2, RNA binding	261	0.82
chr3_98095149_98095420	0.37	Gm42820	predicted gene 42820	26304	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Crem_Jdp2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3	3.5	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.3	2.4	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.3	1.0	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.3	2.3	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.2	0.5	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.2	1.2	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.2	1.5	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.2	0.4	GO:0002572	pro-T cell differentiation(GO:0002572)
0.2	1.4	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.2	0.5	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2	0.5	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1	0.7	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.1	0.6	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1	1.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	1.4	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	1.9	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	0.3	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	1.0	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.1	0.7	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.3	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.3	GO:0010963	regulation of L-arginine import(GO:0010963)
0.1	0.4	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1	1.4	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.1	0.3	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.1	0.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.6	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.3	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.1	0.2	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1	0.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.1	0.2	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.1	0.5	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	0.6	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1	0.2	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.2	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.2	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1	0.4	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.1	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1	0.2	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1	0.2	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.1	0.2	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1	0.5	GO:0021670	lateral ventricle development(GO:0021670)
0.1	0.2	GO:0097107	postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107)
0.1	0.2	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.2	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.1	0.3	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	1.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.2	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.4	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.3	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.1	GO:0030070	insulin processing(GO:0030070)
0.0	0.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.6	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.0	0.3	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.5	GO:1902855	regulation of nonmotile primary cilium assembly(GO:1902855)
0.0	0.2	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.0	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.2	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	1.4	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:1903288	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.2	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.7	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.2	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.3	GO:0030432	peristalsis(GO:0030432)
0.0	0.6	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.2	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.1	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.2	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.2	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.0	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.2	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.1	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.1	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0	0.1	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.1	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.1	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.0	0.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.1	GO:0030953	astral microtubule organization(GO:0030953)
0.0	0.1	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.3	GO:0032402	melanosome transport(GO:0032402)
0.0	0.3	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.0	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.1	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0097343	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	1.2	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.6	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.2	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.0	GO:0021590	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0	0.3	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.1	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.0	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.1	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0034650	cortisol metabolic process(GO:0034650)
0.0	0.1	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0061205	paramesonephric duct development(GO:0061205)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.6	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.0	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.0	0.0	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0060279	positive regulation of ovulation(GO:0060279)
0.0	0.0	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.0	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.2	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.0	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0	0.5	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:2000834	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0	0.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.1	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.0	0.4	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0	0.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.0	0.3	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.0	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0	0.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.1	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.0	0.0	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.0	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0	0.2	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.6	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.1	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.0	0.0	GO:0015747	urate transport(GO:0015747)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.0	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.1	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.0	0.0	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.0	GO:2000822	regulation of fear response(GO:1903365) positive regulation of fear response(GO:1903367) regulation of behavioral fear response(GO:2000822) positive regulation of behavioral fear response(GO:2000987)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0051385	response to mineralocorticoid(GO:0051385)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.0	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.1	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.0	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.0	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.0	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.1	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.1	GO:0032310	prostaglandin secretion(GO:0032310)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0042583	chromaffin granule(GO:0042583)
0.2	3.5	GO:0031045	dense core granule(GO:0031045)
0.2	1.3	GO:0005915	zonula adherens(GO:0005915)
0.2	0.5	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.5	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.4	GO:1990716	axonemal central apparatus(GO:1990716)
0.1	0.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1	0.6	GO:0043203	axon hillock(GO:0043203)
0.1	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.2	GO:0097513	myosin II filament(GO:0097513)
0.1	0.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.7	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	1.2	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.4	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0072534	perineuronal net(GO:0072534)
0.0	0.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.3	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.2	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0044393	microspike(GO:0044393)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.0	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.2	GO:0032797	SMN complex(GO:0032797)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	1.3	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.6	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	2.9	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.0	GO:0036396	MIS complex(GO:0036396)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.3	GO:0008305	integrin complex(GO:0008305)
0.0	0.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.2	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.0	GO:1990393	3M complex(GO:1990393)
0.0	0.6	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.5	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.0	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.0	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.0	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.0	GO:0090533	cation-transporting ATPase complex(GO:0090533)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3	2.2	GO:0003680	AT DNA binding(GO:0003680)
0.3	2.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.3	1.3	GO:0004111	creatine kinase activity(GO:0004111)
0.2	1.8	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.2	0.8	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	0.7	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1	1.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	3.4	GO:0042056	chemoattractant activity(GO:0042056)
0.1	0.6	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.3	GO:2001070	starch binding(GO:2001070)
0.1	1.5	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.5	GO:0070051	fibrinogen binding(GO:0070051)
0.1	1.5	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.1	0.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.3	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.1	0.3	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	3.0	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.3	GO:0042731	PH domain binding(GO:0042731)
0.1	0.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.4	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.2	GO:0046978	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.5	GO:0043912	D-lysine oxidase activity(GO:0043912)
0.1	0.2	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	0.2	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.2	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.1	0.4	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.6	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	1.3	GO:0030507	spectrin binding(GO:0030507)
0.0	0.7	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.3	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	1.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.6	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.5	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.6	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.7	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0038191	neuropilin binding(GO:0038191)
0.0	2.5	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.2	GO:0034871	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.7	GO:0052634	sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	1.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.4	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.3	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0010435	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.5	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0004083	bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.0	0.2	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	1.0	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0019203	carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.3	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.2	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	0.9	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	0.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.5	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	1.1	PID ARF6 PATHWAY	Arf6 signaling events
0.0	1.0	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.9	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.8	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.2	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	2.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	2.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.8	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.8	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	2.9	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism