Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Egr3

Z-value: 0.69

Motif logo

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Transcription factors associated with Egr3

Gene Symbol Gene ID Gene Info
ENSMUSG00000033730.3 Egr3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Egr3chr14_70075014_7007582817820.294526-0.444.5e-04Click!
Egr3chr14_70080459_7008068518330.283702-0.436.0e-04Click!
Egr3chr14_70077013_70077656200.971388-0.382.4e-03Click!
Egr3chr14_70079421_7008043611890.413126-0.339.6e-03Click!
Egr3chr14_70080791_7008107421930.246856-0.273.4e-02Click!

Activity of the Egr3 motif across conditions

Conditions sorted by the z-value of the Egr3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_135836492_135836762 2.36 Tnnt2
troponin T2, cardiac
214
0.9
chr8_67949354_67949997 1.63 Psd3
pleckstrin and Sec7 domain containing 3
2204
0.34
chr7_142662290_142664788 1.57 Igf2os
insulin-like growth factor 2, opposite strand
1599
0.21
chr7_31054545_31055836 1.54 Fxyd1
FXYD domain-containing ion transport regulator 1
219
0.84
chr9_79975154_79975866 1.54 Filip1
filamin A interacting protein 1
2149
0.3
chr5_116421567_116422547 1.53 Hspb8
heat shock protein 8
807
0.51
chr3_10366508_10367397 1.48 Chmp4c
charged multivesicular body protein 4C
6
0.96
chr9_120022870_120023448 1.40 Xirp1
xin actin-binding repeat containing 1
439
0.69
chr7_25687584_25688477 1.39 Tgfb1
transforming growth factor, beta 1
118
0.92
chr1_133245733_133247220 1.28 Plekha6
pleckstrin homology domain containing, family A member 6
370
0.84
chr6_42351556_42352213 1.27 Gm44284
predicted gene, 44284
1022
0.29
chr7_3366653_3367525 1.21 Gm44257
predicted gene, 44257
22991
0.07
chr10_93672331_93673286 1.17 Gm8580
predicted gene 8580
6962
0.14
chr16_58675826_58676599 1.14 Cpox
coproporphyrinogen oxidase
1627
0.28
chr7_143474852_143475242 1.14 Slc22a18
solute carrier family 22 (organic cation transporter), member 18
54
0.96
chr1_51288641_51290950 1.13 Cavin2
caveolae associated 2
669
0.72
chr15_5068848_5069207 1.11 C7
complement component 7
5287
0.14
chr6_34599135_34600037 1.10 Cald1
caldesmon 1
966
0.58
chr7_109588582_109588733 1.06 Denn2b
DENN domain containing 2B
14008
0.15
chr7_120173917_120175138 1.05 Anks4b
ankyrin repeat and sterile alpha motif domain containing 4B
669
0.61
chr16_96201309_96201550 1.00 Sh3bgr
SH3-binding domain glutamic acid-rich protein
700
0.61
chr19_36115022_36115688 0.98 Ankrd1
ankyrin repeat domain 1 (cardiac muscle)
4555
0.22
chr13_46927318_46927739 0.97 Kif13a
kinesin family member 13A
2189
0.22
chr7_49450183_49451616 0.95 Nav2
neuron navigator 2
139
0.97
chr9_21152788_21154079 0.92 Cdc37
cell division cycle 37
3451
0.12
chr3_84189998_84191469 0.90 Trim2
tripartite motif-containing 2
210
0.94
chr9_79976568_79977294 0.89 Filip1
filamin A interacting protein 1
728
0.66
chr6_71261026_71261496 0.89 Smyd1
SET and MYND domain containing 1
971
0.38
chr5_116420481_116421179 0.89 Hspb8
heat shock protein 8
2034
0.22
chr17_29493756_29495031 0.87 Pim1
proviral integration site 1
986
0.37
chr7_89521949_89522690 0.86 Prss23
protease, serine 23
3771
0.2
chr8_45661677_45662126 0.85 Sorbs2
sorbin and SH3 domain containing 2
92
0.97
chr8_121088119_121090419 0.84 Gm27530
predicted gene, 27530
4563
0.13
chr4_133554170_133554634 0.84 Nr0b2
nuclear receptor subfamily 0, group B, member 2
1026
0.34
chr10_111184200_111184466 0.83 Gm17849
predicted gene, 17849
4381
0.18
chr2_19690013_19690679 0.83 Gm24670
predicted gene, 24670
942
0.47
chr18_49979438_49980437 0.81 Tnfaip8
tumor necrosis factor, alpha-induced protein 8
402
0.87
chr7_105762080_105763247 0.81 Gm15645
predicted gene 15645
342
0.76
chr12_86891509_86893562 0.79 Irf2bpl
interferon regulatory factor 2 binding protein-like
7737
0.19
chr18_32556111_32556702 0.78 Gypc
glycophorin C
3574
0.26
chr11_72408624_72409355 0.78 Smtnl2
smoothelin-like 2
2722
0.18
chr7_142576289_142578620 0.77 H19
H19, imprinted maternally expressed transcript
68
0.78
chr6_51193157_51193734 0.77 Mir148a
microRNA 148a
76465
0.1
chr19_53809753_53810553 0.76 Gm16299
predicted gene 16299
14975
0.16
chr19_17322549_17322911 0.75 Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
12706
0.21
chr11_32199441_32199592 0.73 Il9r
interleukin 9 receptor
706
0.53
chr9_21961394_21962913 0.73 Epor
erythropoietin receptor
411
0.68
chr10_69262807_69263449 0.73 Rhobtb1
Rho-related BTB domain containing 1
2509
0.29
chr4_46400544_46400900 0.72 Hemgn
hemogen
3514
0.16
chr19_45446379_45446948 0.69 Btrc
beta-transducin repeat containing protein
1155
0.47
chr1_23228595_23228746 0.68 Gm29506
predicted gene 29506
7003
0.15
chr3_129215238_129216443 0.68 Pitx2
paired-like homeodomain transcription factor 2
1565
0.34
chrX_141476575_141476992 0.67 Col4a5
collagen, type IV, alpha 5
1373
0.41
chr2_84936571_84938205 0.67 Slc43a3
solute carrier family 43, member 3
498
0.71
chr11_100967960_100968469 0.67 Cavin1
caveolae associated 1
2337
0.21
chr5_83352776_83353067 0.66 Tecrl
trans-2,3-enoyl-CoA reductase-like
2035
0.43
chr11_115899671_115901427 0.66 Smim5
small integral membrane protein 5
347
0.75
chr6_84009566_84010358 0.66 Dysf
dysferlin
1047
0.39
chr10_120986145_120986410 0.66 Lemd3
LEM domain containing 3
6945
0.14
chr19_25411319_25412344 0.65 Kank1
KN motif and ankyrin repeat domains 1
5132
0.23
chr12_76533568_76534564 0.65 Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
446
0.63
chr13_30502278_30502625 0.64 Uqcrfs1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
42911
0.16
chr6_134182046_134182799 0.64 Gm17088
predicted gene 17088
10415
0.19
chrX_103481872_103482957 0.63 Xist
inactive X specific transcripts
840
0.37
chr2_105125289_105128976 0.63 Wt1
Wilms tumor 1 homolog
78
0.91
chr1_33945162_33945435 0.61 Gm28631
predicted gene 28631
18387
0.12
chr11_72409718_72409871 0.61 Smtnl2
smoothelin-like 2
1917
0.23
chr18_42052289_42053151 0.61 Sh3rf2
SH3 domain containing ring finger 2
947
0.61
chr2_30716357_30717429 0.60 Gm14488
predicted gene 14488
150
0.94
chr3_129197027_129197497 0.60 Pitx2
paired-like homeodomain transcription factor 2
2616
0.25
chr1_21963069_21963530 0.60 Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
1357
0.56
chr4_138469035_138469593 0.58 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
15000
0.15
chr11_94468500_94470223 0.58 Cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
4280
0.16
chr16_55819320_55820037 0.58 Nfkbiz
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
1163
0.48
chr1_185515159_185516225 0.58 5033404E19Rik
RIKEN cDNA 5033404E19 gene
18304
0.17
chr6_136449235_136449511 0.58 Gm25882
predicted gene, 25882
31561
0.1
chr7_4520460_4522358 0.57 Tnni3
troponin I, cardiac 3
842
0.35
chr4_154635108_154637998 0.57 Prdm16
PR domain containing 16
244
0.83
chr16_94370781_94372079 0.57 Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
412
0.57
chr12_73587917_73588487 0.56 Prkch
protein kinase C, eta
3359
0.25
chr2_35335341_35335492 0.56 Stom
stomatin
1560
0.29
chr5_86180666_86180939 0.56 Uba6
ubiquitin-like modifier activating enzyme 6
7999
0.18
chr14_55004102_55004452 0.56 Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta
9651
0.07
chr1_165717936_165719081 0.56 Gm37073
predicted gene, 37073
3048
0.14
chr9_118592603_118593024 0.56 Gm45897
predicted gene 45897
2618
0.22
chr13_63242151_63243167 0.55 Gm47586
predicted gene, 47586
1562
0.22
chr6_55132322_55132945 0.55 Crhr2
corticotropin releasing hormone receptor 2
208
0.93
chr15_102027906_102029019 0.55 Krt18
keratin 18
282
0.85
chr19_47313387_47314780 0.55 Sh3pxd2a
SH3 and PX domains 2A
668
0.69
chr10_108595779_108596540 0.55 Syt1
synaptotagmin I
40805
0.18
chr17_83218748_83219264 0.54 Pkdcc
protein kinase domain containing, cytoplasmic
1096
0.57
chr12_108370973_108372659 0.54 Eml1
echinoderm microtubule associated protein like 1
859
0.58
chr9_120114964_120115764 0.54 Slc25a38
solute carrier family 25, member 38
375
0.69
chr17_45599296_45600146 0.54 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
115
0.92
chrX_99045264_99045888 0.54 Stard8
START domain containing 8
1592
0.43
chr10_108434849_108435510 0.54 Gm36283
predicted gene, 36283
1486
0.41
chr5_113114547_113114788 0.54 F830115B05Rik
RIKEN cDNA F830115B05 gene
4797
0.12
chr10_76724744_76726005 0.53 Col6a1
collagen, type VI, alpha 1
794
0.59
chr15_57659816_57660144 0.53 Zhx2
zinc fingers and homeoboxes 2
34685
0.17
chr13_55847700_55848325 0.53 Pitx1
paired-like homeodomain transcription factor 1
11820
0.14
chr10_45337043_45337194 0.53 Bves
blood vessel epicardial substance
1346
0.41
chr4_53886310_53887240 0.53 Gm12468
predicted gene 12468
8850
0.17
chr5_98283874_98284382 0.53 Fgf5
fibroblast growth factor 5
29716
0.16
chr6_126163282_126164936 0.52 Ntf3
neurotrophin 3
851
0.73
chr1_184729496_184731200 0.52 Hlx
H2.0-like homeobox
1250
0.37
chr15_79893596_79894135 0.52 Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
1158
0.33
chr7_142657905_142658056 0.52 Igf2
insulin-like growth factor 2
484
0.63
chr15_44462853_44463050 0.52 Pkhd1l1
polycystic kidney and hepatic disease 1-like 1
5398
0.19
chr2_167540595_167541629 0.52 Snai1
snail family zinc finger 1
2917
0.16
chr11_82911356_82912079 0.52 Unc45b
unc-45 myosin chaperone B
464
0.63
chr15_74996448_74997075 0.52 Ly6a
lymphocyte antigen 6 complex, locus A
873
0.36
chr1_40874117_40874621 0.52 Gm5973
predicted gene 5973
10137
0.24
chr9_55283384_55284127 0.51 Nrg4
neuregulin 4
130
0.96
chr11_115778781_115779772 0.51 Tmem94
transmembrane protein 94
1423
0.25
chr2_65953577_65954404 0.51 Gm13617
predicted gene 13617
80
0.98
chr8_84701273_84703379 0.51 Lyl1
lymphoblastomic leukemia 1
545
0.59
chr8_23046398_23046746 0.51 Ank1
ankyrin 1, erythroid
11341
0.17
chr14_118385532_118385782 0.51 Gm5672
predicted gene 5672
9463
0.16
chr15_38567059_38567529 0.50 Gm29697
predicted gene, 29697
6702
0.13
chr11_43383698_43384165 0.50 Gm12148
predicted gene 12148
1551
0.33
chr17_28007198_28009699 0.50 Anks1
ankyrin repeat and SAM domain containing 1
1103
0.37
chr19_53802873_53803024 0.50 Rbm20
RNA binding motif protein 20
9640
0.17
chr1_153751697_153752752 0.50 Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
256
0.82
chr11_69613381_69614022 0.50 Shbg
sex hormone binding globulin
3239
0.07
chr4_154024404_154026596 0.49 Smim1
small integral membrane protein 1
116
0.93
chr5_137610176_137611504 0.49 Pcolce
procollagen C-endopeptidase enhancer protein
138
0.86
chr6_136873814_136874977 0.49 Mgp
matrix Gla protein
1386
0.26
chr10_128344814_128345330 0.49 Gm23182
predicted gene, 23182
4169
0.07
chr3_14890853_14891237 0.49 Car2
carbonic anhydrase 2
4406
0.22
chr14_66257482_66258074 0.49 Ptk2b
PTK2 protein tyrosine kinase 2 beta
23204
0.16
chr6_146219888_146220144 0.49 Itpr2
inositol 1,4,5-triphosphate receptor 2
7527
0.26
chr15_75047655_75047890 0.49 Ly6c1
lymphocyte antigen 6 complex, locus C1
897
0.4
chr9_50752994_50754649 0.49 Cryab
crystallin, alpha B
574
0.54
chr7_49764281_49764691 0.48 Htatip2
HIV-1 Tat interactive protein 2
5333
0.23
chr19_53557067_53557881 0.48 Gm50394
predicted gene, 50394
27819
0.11
chr14_47534282_47534433 0.48 Gm49004
predicted gene, 49004
7623
0.12
chr4_137470074_137470685 0.48 Hspg2
perlecan (heparan sulfate proteoglycan 2)
1576
0.29
chr1_90968520_90969104 0.48 Rab17
RAB17, member RAS oncogene family
736
0.58
chr14_66998875_66999063 0.48 Bnip3l
BCL2/adenovirus E1B interacting protein 3-like
688
0.63
chr6_88195832_88195983 0.48 Gata2
GATA binding protein 2
2016
0.22
chrX_12151122_12152833 0.47 Bcor
BCL6 interacting corepressor
8369
0.25
chr10_45338438_45338763 0.47 Bves
blood vessel epicardial substance
2828
0.24
chr17_78290191_78290620 0.47 Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
10222
0.18
chr13_13358078_13358229 0.47 Gpr137b
G protein-coupled receptor 137B
9652
0.11
chr9_107604198_107605624 0.47 Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
358
0.63
chr3_104790520_104791322 0.47 Rhoc
ras homolog family member C
1062
0.32
chr5_124232299_124232450 0.47 Pitpnm2os1
phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 1
2649
0.16
chr6_34903826_34904483 0.46 Wdr91
WD repeat domain 91
6409
0.13
chr2_90667370_90668252 0.46 Nup160
nucleoporin 160
9404
0.2
chr16_19983095_19983393 0.46 Klhl6
kelch-like 6
207
0.95
chr2_84843620_84843993 0.46 Slc43a1
solute carrier family 43, member 1
3181
0.15
chr16_95705627_95706037 0.46 Ets2
E26 avian leukemia oncogene 2, 3' domain
507
0.82
chr10_117494116_117494978 0.46 Gm32141
predicted gene, 32141
47054
0.1
chr5_32137024_32137228 0.45 Fosl2
fos-like antigen 2
953
0.5
chr8_122735882_122736747 0.45 C230057M02Rik
RIKEN cDNA C230057M02 gene
2197
0.18
chr16_92398977_92399231 0.45 Rcan1
regulator of calcineurin 1
874
0.51
chr10_122960853_122961339 0.45 Mirlet7i
microRNA let7i
24628
0.15
chr16_38363311_38363597 0.45 Popdc2
popeye domain containing 2
1209
0.35
chr10_81196473_81196648 0.45 Atcayos
ataxia, cerebellar, Cayman type, opposite strand
1869
0.13
chr15_89425017_89425997 0.45 Cpt1b
carnitine palmitoyltransferase 1b, muscle
288
0.74
chr9_119962629_119963694 0.44 Ttc21a
tetratricopeptide repeat domain 21A
1543
0.24
chr2_102551752_102552240 0.44 Pamr1
peptidase domain containing associated with muscle regeneration 1
1847
0.45
chr19_29707870_29708563 0.44 Mlana
melan-A
10282
0.19
chr8_18950058_18950375 0.44 Xkr5
X-linked Kx blood group related 5
655
0.59
chr9_79975909_79976072 0.44 Filip1
filamin A interacting protein 1
1669
0.36
chr13_3891572_3893506 0.44 Net1
neuroepithelial cell transforming gene 1
894
0.46
chr3_59028229_59029161 0.44 Med12l
mediator complex subunit 12-like
21717
0.13
chr11_85829139_85831432 0.44 2610027K06Rik
RIKEN cDNA 2610027K06 gene
1924
0.21
chr2_68435653_68436705 0.44 Stk39
serine/threonine kinase 39
35761
0.16
chr9_110676440_110676899 0.44 Gm35715
predicted gene, 35715
1715
0.22
chr3_138069501_138070764 0.43 1110002E22Rik
RIKEN cDNA 1110002E22 gene
1465
0.3
chr10_99284362_99285186 0.43 Gm48089
predicted gene, 48089
9978
0.12
chr13_63273798_63275383 0.43 Gm47585
predicted gene, 47585
990
0.28
chr11_115901491_115901642 0.43 Smim5
small integral membrane protein 5
1364
0.24
chr11_85833878_85836704 0.43 Tbx2
T-box 2
2740
0.17
chr10_77583080_77584320 0.43 Pttg1ip
pituitary tumor-transforming 1 interacting protein
245
0.86
chr18_53462509_53463403 0.43 Prdm6
PR domain containing 6
627
0.8
chr3_89315122_89317455 0.43 Gm15998
predicted gene 15998
849
0.32
chr6_52178790_52180823 0.43 5730596B20Rik
RIKEN cDNA 5730596B20 gene
2308
0.09
chr4_43507951_43509367 0.43 Gm12454
predicted gene 12454
65
0.55
chr8_4656570_4656923 0.43 Gm45224
predicted gene 45224
4682
0.13
chr2_125672728_125673971 0.43 Shc4
SHC (Src homology 2 domain containing) family, member 4
153
0.64
chr1_135324343_135325907 0.43 Lmod1
leiomodin 1 (smooth muscle)
318
0.83
chr9_77636642_77636866 0.42 Klhl31
kelch-like 31
254
0.92
chr8_104609120_104609451 0.42 Cdh16
cadherin 16
3979
0.11
chr10_127515904_127517428 0.42 Ndufa4l2
Ndufa4, mitochondrial complex associated like 2
1699
0.19
chr7_140954618_140955957 0.42 Gm45717
predicted gene 45717
650
0.32
chr15_25680042_25680346 0.42 Gm2862
predicted gene 2862
1604
0.38
chr12_31077047_31077429 0.42 Fam110c
family with sequence similarity 110, member C
3377
0.17
chr11_117611027_117611290 0.42 2900041M22Rik
RIKEN cDNA 2900041M22 gene
89
0.97
chr15_101294730_101294931 0.42 Smim41
small integral membrane protein 41
1598
0.22
chr1_74035187_74035546 0.42 Tns1
tensin 1
1767
0.41
chr1_171439042_171439737 0.42 F11r
F11 receptor
1810
0.19
chr2_167367751_167368519 0.41 B4galt5
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
18952
0.17
chr9_21227741_21228074 0.41 Gm16754
predicted gene, 16754
2504
0.14
chr5_34525649_34526962 0.41 Sh3bp2
SH3-domain binding protein 2
459
0.69
chr13_75797358_75797520 0.41 Gm8288
predicted gene 8288
5267
0.16
chr3_89436767_89437632 0.41 Pbxip1
pre B cell leukemia transcription factor interacting protein 1
443
0.64
chr2_135536052_135537171 0.41 9630028H03Rik
RIKEN cDNA 9630028H03 gene
46685
0.17
chr2_69670826_69672050 0.41 Klhl41
kelch-like 41
1318
0.37

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Egr3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.5 1.6 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.4 1.4 GO:0009838 abscission(GO:0009838)
0.3 1.3 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.3 1.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 0.8 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.2 0.7 GO:0007403 glial cell fate determination(GO:0007403)
0.2 0.6 GO:0060931 sinoatrial node cell development(GO:0060931)
0.2 0.7 GO:0035482 gastric motility(GO:0035482)
0.1 0.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.4 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.6 GO:1904970 brush border assembly(GO:1904970)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.4 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
0.1 0.2 GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
0.1 0.4 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.4 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.6 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.1 GO:0061626 pharyngeal arch artery morphogenesis(GO:0061626)
0.1 0.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 0.4 GO:0001834 trophectodermal cell proliferation(GO:0001834)
0.1 0.4 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.1 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.1 GO:0048818 positive regulation of hair follicle maturation(GO:0048818)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.4 GO:0032196 transposition(GO:0032196)
0.1 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0051794 regulation of catagen(GO:0051794)
0.1 0.2 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 0.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 0.2 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.1 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.1 0.1 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.2 GO:1902988 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.1 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.3 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.3 GO:1904683 regulation of metalloendopeptidase activity(GO:1904683)
0.1 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.1 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.6 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.2 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.1 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 0.3 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.2 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.1 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.1 GO:0061738 late endosomal microautophagy(GO:0061738)
0.1 0.3 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960)
0.1 0.4 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.2 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.1 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.1 GO:0048382 mesendoderm development(GO:0048382)
0.1 0.1 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 0.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.6 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.1 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.2 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.4 GO:0060613 fat pad development(GO:0060613)
0.1 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672) dipeptide transport(GO:0042938)
0.1 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.2 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.1 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.1 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.1 GO:0061511 centriole elongation(GO:0061511)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.3 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0060268 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.0 1.3 GO:0045214 sarcomere organization(GO:0045214)
0.0 1.2 GO:0015893 drug transport(GO:0015893)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.2 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.0 0.2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.1 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.0 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.6 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.0 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 0.1 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.5 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.5 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.2 GO:0052055 modulation by symbiont of host molecular function(GO:0052055)
0.0 0.3 GO:0060713 labyrinthine layer morphogenesis(GO:0060713)
0.0 0.2 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.5 GO:0002467 germinal center formation(GO:0002467)
0.0 0.2 GO:0001805 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0 0.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.6 GO:0030903 notochord development(GO:0030903)
0.0 0.4 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0033668 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0051385 response to mineralocorticoid(GO:0051385)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0070488 neutrophil aggregation(GO:0070488)
0.0 0.1 GO:0071455 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0060486 Clara cell differentiation(GO:0060486)
0.0 0.1 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.2 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0060525 prostate glandular acinus development(GO:0060525) prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0001907 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.2 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.3 GO:0014041 regulation of neuron maturation(GO:0014041)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.3 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.0 0.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.3 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:1903429 regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.0 GO:1904177 regulation of adipose tissue development(GO:1904177) positive regulation of adipose tissue development(GO:1904179)
0.0 0.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.0 GO:0021546 rhombomere development(GO:0021546)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.2 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0060558 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.0 0.3 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.2 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0045606 positive regulation of epidermal cell differentiation(GO:0045606)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.0 GO:0086064 cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.1 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.1 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.0 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.0 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.0 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.0 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.0 0.3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.0 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:2001260 regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.0 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0010611 regulation of cardiac muscle hypertrophy(GO:0010611)
0.0 0.1 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.0 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.0 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0010573 vascular endothelial growth factor production(GO:0010573)
0.0 0.1 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0018119 peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.0 GO:1905214 regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
0.0 0.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.0 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.2 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0070671 response to interleukin-12(GO:0070671)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.0 GO:0042023 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.0 GO:0045908 negative regulation of vasodilation(GO:0045908)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.0 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.0 GO:2000726 negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.0 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.0 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.0 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.0 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.0 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.2 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.1 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.0 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.1 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.0 0.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.0 GO:0072300 positive regulation of metanephric glomerulus development(GO:0072300)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.0 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
0.0 0.1 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.0 GO:1904749 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.4 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:0032096 negative regulation of response to food(GO:0032096)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0 0.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.0 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.0 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.0 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.3 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.5 GO:0051782 negative regulation of cell division(GO:0051782)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0007614 short-term memory(GO:0007614)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:1900238 cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.0 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.0 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.0 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.3 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.0 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.0 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0033504 floor plate development(GO:0033504)
0.0 0.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.0 0.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.0 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.0 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.0 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.1 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.0 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.4 GO:0001892 embryonic placenta development(GO:0001892)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.0 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.0 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.0 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.0 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:2000778 positive regulation of interleukin-6 secretion(GO:2000778)
0.0 0.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.0 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 0.0 GO:0030220 platelet formation(GO:0030220)
0.0 0.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0097369 sodium ion import(GO:0097369)
0.0 0.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.0 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.0 0.0 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0005861 troponin complex(GO:0005861)
0.2 1.7 GO:0090543 Flemming body(GO:0090543)
0.2 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.4 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.2 GO:0070552 BRISC complex(GO:0070552)
0.1 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.2 GO:0000805 X chromosome(GO:0000805)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.2 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 3.2 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0036379 myofilament(GO:0036379)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.9 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511)
0.0 0.3 GO:0031672 A band(GO:0031672)
0.0 0.0 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.0 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0044853 plasma membrane raft(GO:0044853)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.0 GO:1990696 USH2 complex(GO:1990696)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.0 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.0 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0030172 troponin C binding(GO:0030172)
0.4 1.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.1 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.1 0.4 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.1 0.2 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0034912 enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.2 GO:0044682 N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.0 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.0 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0001226 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0015254 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0034842 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.3 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.0 GO:0015250 water channel activity(GO:0015250)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204) urea channel activity(GO:0015265)
0.0 0.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.0 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.2 GO:0019956 chemokine binding(GO:0019956)
0.0 0.0 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.0 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.0 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.1 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID SHP2 PATHWAY SHP2 signaling
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.6 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.0 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21