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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Etv4

Z-value: 0.44

Motif logo

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Transcription factors associated with Etv4

Gene Symbol Gene ID Gene Info
Etv4
ENSMUSG00000017724.8 ets variant 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_101814398_101814872Etv4292640.1206650.496.8e-05Click!
chr11_101784179_101785383Etv4670.9673600.356.0e-03Click!
chr11_101782309_101782733Etv418670.2864260.356.1e-03Click!
chr11_101814893_101815371Etv4297610.1196780.339.3e-03Click!
chr11_101806597_101806748Etv4213010.1357670.311.6e-02Click!

Activity of the Etv4 motif across conditions

Conditions sorted by the z-value of the Etv4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrX_170674573_170675954 10.21 Asmt
 acetylserotonin O-methyltransferase
 2619
 0.41
chr7_4518554_4518985 1.83 Tnni3
 troponin I, cardiac 3
 995
 0.29
chr12_3236855_3237648 0.72 Rab10os
 RAB10, member RAS oncogene family, opposite strand
 640
 0.66
chr9_124439879_124441093 0.71 Ppp2r3d
 protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
 382
 0.83
chr14_106163700_106163851 0.66 Gm48971
 predicted gene, 48971
 48203
 0.12
chr5_112215410_112216373 0.64 Gm26953
 predicted gene, 26953
 430
 0.76
chr8_45509543_45510137 0.56 Sorbs2
 sorbin and SH3 domain containing 2
 1922
 0.33
chr11_94045498_94046076 0.54 Spag9
 sperm associated antigen 9
 1422
 0.4
chr4_89285556_89285707 0.54 Cdkn2a
 cyclin dependent kinase inhibitor 2A
 3439
 0.19
chr2_71525880_71527745 0.51 Dlx1as
 distal-less homeobox 1, antisense
 1107
 0.33
chr13_83721518_83722206 0.51 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 481
 0.73
chr1_133735425_133736534 0.50 Mir6903
 microRNA 6903
 9334
 0.14
chr10_29143400_29144848 0.44 Soga3
 SOGA family member 3
 65
 0.5
chr3_30649995_30651146 0.44 Lrriq4
 leucine-rich repeats and IQ motif containing 4
 2684
 0.17
chr1_184235265_184236073 0.41 Gm37223
 predicted gene, 37223
 122660
 0.05
chr4_45824847_45825701 0.40 Igfbpl1
 insulin-like growth factor binding protein-like 1
 1649
 0.31
chr12_29529828_29531185 0.38 Gm20208
 predicted gene, 20208
 609
 0.74
chr3_108410436_108412210 0.38 Celsr2
 cadherin, EGF LAG seven-pass G-type receptor 2
 4229
 0.11
chr2_140666876_140668088 0.37 Flrt3
 fibronectin leucine rich transmembrane protein 3
 3918
 0.37
chr13_112695809_112696082 0.37 Gm18883
 predicted gene, 18883
 3734
 0.17
chr16_10446425_10446612 0.37 Tvp23a
 trans-golgi network vesicle protein 23A
 626
 0.68
chr12_29528407_29529244 0.36 Myt1l
 myelin transcription factor 1-like
 424
 0.85
chr4_89285170_89285321 0.35 Cdkn2a
 cyclin dependent kinase inhibitor 2A
 3053
 0.2
chr9_35423074_35423780 0.34 Cdon
 cell adhesion molecule-related/down-regulated by oncogenes
 161
 0.95
chr7_25294533_25294696 0.34 Cic
 capicua transcriptional repressor
 1594
 0.18
chr14_122475443_122476757 0.34 Zic2
 zinc finger protein of the cerebellum 2
 665
 0.44
chr7_44441951_44442938 0.33 Lrrc4b
 leucine rich repeat containing 4B
 41
 0.93
chr3_34656299_34657721 0.33 Sox2ot
 SOX2 overlapping transcript (non-protein coding)
 974
 0.4
chr1_42691569_42692627 0.33 Pantr1
 POU domain, class 3, transcription factor 3 adjacent noncoding transcript 1
 995
 0.42
chr3_94479508_94480443 0.33 Riiad1
 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
 366
 0.63
chr12_12263781_12264571 0.32 Fam49a
 family with sequence similarity 49, member A
 1987
 0.46
chr12_117157079_117158175 0.32 Gm10421
 predicted gene 10421
 5976
 0.31
chr7_4920681_4922210 0.32 Nat14
 N-acetyltransferase 14
 583
 0.48
chr17_46617075_46618033 0.32 Ptk7
 PTK7 protein tyrosine kinase 7
 11950
 0.1
chrX_123943318_123943469 0.32 Rps12-ps20
 ribosomal protein S12, pseudogene 20
 13881
 0.22
chr1_5916517_5917959 0.32 Npbwr1
 neuropeptides B/W receptor 1
 160
 0.97
chr4_156183474_156184054 0.31 Agrn
 agrin
 2137
 0.17
chr1_115684558_115685809 0.31 Cntnap5a
 contactin associated protein-like 5A
 427
 0.58
chr6_121472423_121472626 0.31 Iqsec3
 IQ motif and Sec7 domain 3
 1099
 0.53
chr5_120433178_120434996 0.31 Gm27199
 predicted gene 27199
 2320
 0.19
chr12_33928070_33929277 0.31 Gm40383
 predicted gene, 40383
 217
 0.53
chr4_96552598_96553907 0.31 Cyp2j6
 cytochrome P450, family 2, subfamily j, polypeptide 6
 409
 0.87
chr8_94994139_94995207 0.30 Adgrg1
 adhesion G protein-coupled receptor G1
 77
 0.95
chr3_114904046_114905354 0.30 Olfm3
 olfactomedin 3
 65
 0.98
chr9_29943252_29944148 0.30 Ntm
 neurotrimin
 19419
 0.28
chr10_80298461_80300404 0.30 Apc2
 APC regulator of WNT signaling pathway 2
 341
 0.69
chr12_65428156_65429051 0.30 Gm26015
 predicted gene, 26015
 22633
 0.22
chr3_26332588_26333347 0.29 Nlgn1
 neuroligin 1
 507
 0.68
chr6_13835523_13837039 0.29 Gpr85
 G protein-coupled receptor 85
 960
 0.59
chr15_95525022_95525792 0.29 Nell2
 NEL-like 2
 2771
 0.35
chr6_90781027_90782541 0.29 Iqsec1
 IQ motif and Sec7 domain 1
 188
 0.94
chr4_48586042_48586294 0.29 Tmeff1
 transmembrane protein with EGF-like and two follistatin-like domains 1
 617
 0.75
chr7_126978893_126979102 0.28 Cdipt
 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
 764
 0.32
chr8_41052368_41053980 0.28 Gm16193
 predicted gene 16193
 64
 0.96
chr5_138278285_138278436 0.28 Gpc2
 glypican 2 (cerebroglycan)
 123
 0.87
chr16_96280491_96281572 0.28 B3galt5
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
 233
 0.93
chr14_76420544_76421824 0.27 Tsc22d1
 TSC22 domain family, member 1
 2356
 0.39
chr18_15060980_15061427 0.27 Kctd1
 potassium channel tetramerisation domain containing 1
 686
 0.74
chr9_97017174_97017806 0.27 Gm16010
 predicted gene 16010
 16
 0.96
chr13_51566607_51568077 0.27 Shc3
 src homology 2 domain-containing transforming protein C3
 258
 0.94
chr4_13746200_13747057 0.27 Runx1t1
 RUNX1 translocation partner 1
 3192
 0.37
chr9_108824114_108825614 0.27 Gm35025
 predicted gene, 35025
 3
 0.87
chr12_3370750_3371679 0.27 Gm48511
 predicted gene, 48511
 2785
 0.18
chr1_6733530_6734383 0.27 St18
 suppression of tumorigenicity 18
 914
 0.7
chr7_78884387_78884983 0.27 Mir7-2
 microRNA 7-2
 3592
 0.14
chr10_60115211_60116020 0.27 Spock2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
 9147
 0.19
chr4_15880938_15882113 0.26 Calb1
 calbindin 1
 259
 0.9
chr10_127268122_127269422 0.26 Dctn2
 dynactin 2
 2385
 0.12
chr16_9994378_9995594 0.26 Grin2a
 glutamate receptor, ionotropic, NMDA2A (epsilon 1)
 63
 0.98
chr2_166152712_166153273 0.26 Sulf2
 sulfatase 2
 1431
 0.4
chr5_34182980_34183403 0.26 Mxd4
 Max dimerization protein 4
 1179
 0.3
chr2_51144318_51145477 0.26 Rnd3
 Rho family GTPase 3
 4197
 0.29
chr1_104768492_104769666 0.26 Cdh20
 cadherin 20
 550
 0.79
chr3_34197711_34199105 0.26 Sox2ot
 SOX2 overlapping transcript (non-protein coding)
 1544
 0.41
chr7_10480473_10481196 0.25 Gm30645
 predicted gene, 30645
 11141
 0.11
chr5_148265188_148266164 0.25 Mtus2
 microtubule associated tumor suppressor candidate 2
 331
 0.91
chr14_14345697_14346878 0.25 Il3ra
 interleukin 3 receptor, alpha chain
 12
 0.94
chr11_69043818_69044451 0.25 Aurkb
 aurora kinase B
 1513
 0.17
chr7_126277403_126277977 0.25 Sbk1
 SH3-binding kinase 1
 4290
 0.14
chr10_3863416_3864702 0.25 Gm16149
 predicted gene 16149
 5548
 0.21
chr19_4758474_4759201 0.25 Rbm4b
 RNA binding motif protein 4B
 1932
 0.18
chr11_76466993_76468433 0.25 Abr
 active BCR-related gene
 585
 0.77
chr11_57013425_57013750 0.25 Gria1
 glutamate receptor, ionotropic, AMPA1 (alpha 1)
 541
 0.88
chr14_79773410_79774519 0.25 Pcdh8
 protocadherin 8
 2652
 0.21
chr10_59950302_59950479 0.25 Ddit4
 DNA-damage-inducible transcript 4
 1444
 0.4
chr2_20339506_20340619 0.25 Etl4
 enhancer trap locus 4
 238
 0.94
chr8_121300864_121302289 0.24 Gm26815
 predicted gene, 26815
 55260
 0.11
chr9_52145956_52147029 0.24 Zc3h12c
 zinc finger CCCH type containing 12C
 21619
 0.17
chr2_65929929_65930575 0.24 Csrnp3
 cysteine-serine-rich nuclear protein 3
 115
 0.97
chr4_82499658_82501360 0.24 Nfib
 nuclear factor I/B
 1193
 0.5
chr12_117149811_117150131 0.24 Gm10421
 predicted gene 10421
 1244
 0.61
chr13_51594475_51595717 0.24 Shc3
 src homology 2 domain-containing transforming protein C3
 25609
 0.16
chr4_22835212_22836357 0.24 Gm24078
 predicted gene, 24078
 88653
 0.09
chr14_14351494_14351697 0.24 Il3ra
 interleukin 3 receptor, alpha chain
 1974
 0.2
chr15_92160888_92162023 0.24 Cntn1
 contactin 1
 98
 0.98
chr14_68126289_68127413 0.23 Nefm
 neurofilament, medium polypeptide
 2005
 0.3
chr7_133757893_133758428 0.23 Dhx32
 DEAH (Asp-Glu-Ala-His) box polypeptide 32
 1312
 0.34
chr1_25832036_25832712 0.23 Gm9884
 predicted gene 9884
 1717
 0.22
chr18_15060481_15060964 0.23 Kctd1
 potassium channel tetramerisation domain containing 1
 1167
 0.55
chr7_67421454_67422158 0.23 Gm33926
 predicted gene, 33926
 22127
 0.17
chr9_47533891_47534042 0.23 Cadm1
 cell adhesion molecule 1
 3593
 0.24
chr11_64520049_64520796 0.23 Gm24275
 predicted gene, 24275
 70218
 0.12
chr2_71536695_71536971 0.23 Dlx1as
 distal-less homeobox 1, antisense
 977
 0.45
chr1_34677886_34678995 0.23 Arhgef4
 Rho guanine nucleotide exchange factor (GEF) 4
 252
 0.89
chr2_167775422_167775573 0.23 Gm14321
 predicted gene 14321
 1970
 0.27
chr2_80128704_80129752 0.23 Pde1a
 phosphodiesterase 1A, calmodulin-dependent
 230
 0.94
chr14_28508967_28511864 0.23 Wnt5a
 wingless-type MMTV integration site family, member 5A
 203
 0.89
chr3_31097203_31098928 0.23 Skil
 SKI-like
 1232
 0.48
chr11_71749802_71749953 0.23 Wscd1
 WSC domain containing 1
 43
 0.97
chr1_77503797_77505059 0.23 Mir6352
 microRNA 6352
 7660
 0.19
chr7_81494043_81494194 0.23 Ap3b2
 adaptor-related protein complex 3, beta 2 subunit
 193
 0.89
chr5_28466220_28467111 0.23 9530036O11Rik
 RIKEN cDNA 9530036O11Rik
 319
 0.7
chr16_14906219_14907566 0.23 Efcab1
 EF-hand calcium binding domain 1
 227
 0.95
chr4_41693576_41694021 0.23 Cntfr
 ciliary neurotrophic factor receptor
 1644
 0.21
chr14_12339117_12339550 0.23 Gm24578
 predicted gene, 24578
 5429
 0.13
chr13_105249326_105250833 0.23 Rnf180
 ring finger protein 180
 20960
 0.22
chr12_5374545_5374864 0.23 Klhl29
 kelch-like 29
 978
 0.45
chr10_19358667_19359238 0.23 Olig3
 oligodendrocyte transcription factor 3
 2419
 0.35
chr4_72203288_72203508 0.22 C630043F03Rik
 RIKEN cDNA C630043F03 gene
 2050
 0.31
chr17_35160468_35162406 0.22 Gm23442
 predicted gene, 23442
 1259
 0.13
chr7_87586513_87587584 0.22 Grm5
 glutamate receptor, metabotropic 5
 2650
 0.4
chr11_113621749_113621900 0.22 Sstr2
 somatostatin receptor 2
 2348
 0.25
chr3_83768357_83769273 0.22 Sfrp2
 secreted frizzled-related protein 2
 1962
 0.31
chr11_103776117_103777283 0.22 Wnt3
 wingless-type MMTV integration site family, member 3
 2550
 0.24
chr7_16948034_16948663 0.22 Pnmal2
 PNMA-like 2
 3666
 0.11
chr2_129908592_129909805 0.22 Gm28196
 predicted gene 28196
 39370
 0.15
chr2_155514247_155515194 0.22 Ggt7
 gamma-glutamyltransferase 7
 128
 0.92
chr11_88584998_88585279 0.22 Msi2
 musashi RNA-binding protein 2
 5009
 0.28
chr8_109245493_109246323 0.22 D030068K23Rik
 RIKEN cDNA D030068K23 gene
 3958
 0.33
chr1_131523488_131524457 0.22 Srgap2
 SLIT-ROBO Rho GTPase activating protein 2
 3375
 0.18
chr3_55782570_55784448 0.22 Nbea
 neurobeachin
 19
 0.96
chr12_27140199_27140495 0.22 Gm9866
 predicted gene 9866
 19964
 0.27
chr17_93201490_93204144 0.22 Adcyap1
 adenylate cyclase activating polypeptide 1
 741
 0.65
chr17_28256852_28257467 0.22 Ppard
 peroxisome proliferator activator receptor delta
 14549
 0.11
chr1_166256819_166257273 0.22 Ildr2
 immunoglobulin-like domain containing receptor 2
 2853
 0.25
chr12_91683421_91686419 0.22 Gm16876
 predicted gene, 16876
 255
 0.86
chr5_98182267_98183697 0.21 Prdm8
 PR domain containing 8
 2004
 0.26
chr3_87539034_87539185 0.21 ETV3L
 ets variant 3-like
 10990
 0.16
chrX_134405492_134405850 0.21 Drp2
 dystrophin related protein 2
 869
 0.59
chr7_79514267_79514939 0.21 Mir9-3hg
 Mir9-3 host gene
 629
 0.46
chr5_5507730_5508026 0.21 Cldn12
 claudin 12
 6571
 0.17
chr15_74563319_74564610 0.21 Adgrb1
 adhesion G protein-coupled receptor B1
 63
 0.61
chrX_101708550_101709190 0.21 Gm9089
 predicted gene 9089
 691
 0.52
chr9_78377654_78378912 0.21 Ooep
 oocyte expressed protein
 442
 0.65
chr5_66967831_66968776 0.21 Limch1
 LIM and calponin homology domains 1
 113
 0.93
chr8_58912073_58913264 0.21 Galntl6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
 28
 0.88
chr2_120848173_120848373 0.21 Cdan1
 congenital dyserythropoietic anemia, type I (human)
 1855
 0.22
chrX_96712746_96713886 0.21 Gpr165
 G protein-coupled receptor 165
 125
 0.98
chr17_52600782_52601825 0.21 Gm27217
 predicted gene 27217
 1357
 0.38
chr1_119420327_119420935 0.21 Inhbb
 inhibin beta-B
 1617
 0.38
chr9_102721179_102722320 0.21 Amotl2
 angiomotin-like 2
 567
 0.65
chr4_156182317_156182745 0.21 Agrn
 agrin
 3370
 0.13
chr4_99118711_99119482 0.20 Dock7
 dedicator of cytokinesis 7
 1666
 0.29
chr4_141998561_141998861 0.20 Fhad1
 forkhead-associated (FHA) phosphopeptide binding domain 1
 12926
 0.12
chr9_48517322_48517969 0.20 Gm23653
 predicted gene, 23653
 10585
 0.15
chrX_74310114_74310288 0.20 Gdi1
 guanosine diphosphate (GDP) dissociation inhibitor 1
 180
 0.84
chr4_72195085_72196381 0.20 Tle1
 transducin-like enhancer of split 1
 3359
 0.26
chr7_90886512_90887836 0.20 Gm45159
 predicted gene 45159
 102
 0.88
chr16_22160432_22161001 0.20 Igf2bp2
 insulin-like growth factor 2 mRNA binding protein 2
 734
 0.66
chr14_13283913_13285295 0.20 Gm5087
 predicted gene 5087
 26
 0.69
chr2_151966993_151968089 0.20 Mir1953
 microRNA 1953
 76
 0.96
chr9_87727084_87728023 0.20 D030062O11Rik
 RIKEN cDNA D030062O11 gene
 1732
 0.31
chr9_29411568_29412757 0.20 Ntm
 neurotrimin
 42
 0.99
chr15_100872381_100872532 0.20 Scn8a
 sodium channel, voltage-gated, type VIII, alpha
 1036
 0.52
chr9_121493633_121494845 0.20 Cck
 cholecystokinin
 271
 0.9
chr18_16804620_16805078 0.20 Cdh2
 cadherin 2
 3613
 0.25
chr4_123001785_123002093 0.20 Mycl
 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived
 2600
 0.21
chr12_3368013_3368276 0.20 Gm48511
 predicted gene, 48511
 285
 0.85
chr2_38824726_38825619 0.20 Nr6a1os
 nuclear receptor subfamily 6, group A, member 1, opposite strand
 1831
 0.22
chr19_55898749_55899177 0.20 Tcf7l2
 transcription factor 7 like 2, T cell specific, HMG box
 654
 0.79
chr3_89523444_89523616 0.20 Kcnn3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
 3366
 0.2
chr1_56969244_56970464 0.20 Satb2
 special AT-rich sequence binding protein 2
 14
 0.97
chr12_27334769_27335068 0.20 Sox11
 SRY (sex determining region Y)-box 11
 7656
 0.29
chr17_8592901_8593278 0.20 Gm15425
 predicted gene 15425
 24229
 0.18
chr8_70691465_70691881 0.20 Jund
 jun D proto-oncogene
 7276
 0.08
chr15_101995407_101995688 0.20 Gm36026
 predicted gene, 36026
 8665
 0.11
chr11_120045840_120045991 0.20 Aatk
 apoptosis-associated tyrosine kinase
 1155
 0.3
chr6_144205160_144205647 0.20 Sox5
 SRY (sex determining region Y)-box 5
 976
 0.71
chr16_81200177_81200598 0.20 Ncam2
 neural cell adhesion molecule 2
 310
 0.93
chr9_123351055_123351227 0.20 Lars2
 leucyl-tRNA synthetase, mitochondrial
 15786
 0.16
chr10_14759598_14760682 0.20 Nmbr
 neuromedin B receptor
 17
 0.91
chr8_12915306_12916734 0.20 Mcf2l
 mcf.2 transforming sequence-like
 45
 0.76
chr6_30957331_30957937 0.19 Klf14
 Kruppel-like factor 14
 1444
 0.38
chr10_23345710_23346907 0.19 Eya4
 EYA transcriptional coactivator and phosphatase 4
 3579
 0.36
chr19_55746711_55749175 0.19 Tcf7l2
 transcription factor 7 like 2, T cell specific, HMG box
 5098
 0.32
chr15_73839069_73840200 0.19 Mroh5
 maestro heat-like repeat family member 5
 37
 0.97
chr11_87759834_87761999 0.19 Tspoap1
 TSPO associated protein 1
 329
 0.75
chr9_52141326_52141501 0.19 Mir6244
 microRNA 6244
 25790
 0.16
chr15_89840994_89842160 0.19 Syt10
 synaptotagmin X
 283
 0.93
chr7_45802610_45802761 0.19 Cyth2
 cytohesin 2
 8203
 0.07
chr1_77507828_77508329 0.19 Epha4
 Eph receptor A4
 7001
 0.19
chr17_46976854_46977005 0.19 Ubr2
 ubiquitin protein ligase E3 component n-recognin 2
 24774
 0.15
chr19_12488341_12489388 0.19 Dtx4
 deltex 4, E3 ubiquitin ligase
 12590
 0.1
chr9_111352762_111353061 0.19 Trank1
 tetratricopeptide repeat and ankyrin repeat containing 1
 21909
 0.18
chr1_151685824_151686091 0.19 Fam129a
 family with sequence similarity 129, member A
 8790
 0.22
chr10_41715763_41715983 0.19 Ccdc162
 coiled-coil domain containing 162
 761
 0.57
chr2_73572450_73573344 0.19 Chrna1
 cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
 7441
 0.15
chr4_54945891_54946424 0.19 Zfp462
 zinc finger protein 462
 1109
 0.63
chr2_4152602_4153854 0.19 Frmd4a
 FERM domain containing 4A
 356
 0.79
chr2_164970287_164971705 0.19 Slc12a5
 solute carrier family 12, member 5
 2715
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.1 0.3 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.1 0.3 GO:0033058 directional locomotion(GO:0033058)
0.1 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.2 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.1 0.3 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.3 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.1 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.2 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.2 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.2 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.1 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0061356 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.0 0.1 GO:1990123 L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.2 GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.4 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1902302 regulation of potassium ion export(GO:1902302)
0.0 0.2 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.1 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.0 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.0 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.0 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.0 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0061525 hindgut development(GO:0061525)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:0048880 sensory system development(GO:0048880)
0.0 0.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.0 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.0 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0072235 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0072174 metanephric tubule formation(GO:0072174)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.0 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.0 0.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.0 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.0 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.0 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.0 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.0 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.0 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.0 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.0 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.0 GO:1904938 dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.0 0.0 GO:0015817 histidine transport(GO:0015817)
0.0 0.0 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.2 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.0 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.0 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.0 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.0 GO:0042891 antibiotic transport(GO:0042891)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0030432 peristalsis(GO:0030432)
0.0 0.1 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.0 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.0 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.0 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:1902913 positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.0 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.0 GO:0031034 myosin filament assembly(GO:0031034)
0.0 0.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.1 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.0 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0000802 transverse filament(GO:0000802)
0.0 0.3 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.0 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030172 troponin C binding(GO:0030172)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.2 GO:0031014 troponin T binding(GO:0031014)
0.1 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0004946 bombesin receptor activity(GO:0004946)
0.1 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 3.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.3 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.0 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.0 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)