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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Etv4

Z-value: 0.44

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Transcription factors associated with Etv4

Gene Symbol	Gene ID	Gene Info
Etv4 Ensembl NCBI MGI UniProt	ENSMUSG00000017724.8	Etv4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Etv4	chr11_101814398_101814872	29264	0.120665	0.49	6.8e-05	Click!
Etv4	chr11_101784179_101785383	67	0.967360	0.35	6.0e-03	Click!
Etv4	chr11_101782309_101782733	1867	0.286426	0.35	6.1e-03	Click!
Etv4	chr11_101814893_101815371	29761	0.119678	0.33	9.3e-03	Click!
Etv4	chr11_101806597_101806748	21301	0.135767	0.31	1.6e-02	Click!

Activity of the Etv4 motif across conditions

Conditions sorted by the z-value of the Etv4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrX_170674573_170675954	10.21	Asmt	acetylserotonin O-methyltransferase	2619	0.41
chr7_4518554_4518985	1.83	Tnni3	troponin I, cardiac 3	995	0.29
chr12_3236855_3237648	0.72	Rab10os	RAB10, member RAS oncogene family, opposite strand	640	0.66
chr9_124439879_124441093	0.71	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	382	0.83
chr14_106163700_106163851	0.66	Gm48971	predicted gene, 48971	48203	0.12
chr5_112215410_112216373	0.64	Gm26953	predicted gene, 26953	430	0.76
chr8_45509543_45510137	0.56	Sorbs2	sorbin and SH3 domain containing 2	1922	0.33
chr11_94045498_94046076	0.54	Spag9	sperm associated antigen 9	1422	0.4
chr4_89285556_89285707	0.54	Cdkn2a	cyclin dependent kinase inhibitor 2A	3439	0.19
chr2_71525880_71527745	0.51	Dlx1as	distal-less homeobox 1, antisense	1107	0.33
chr13_83721518_83722206	0.51	C130071C03Rik	RIKEN cDNA C130071C03 gene	481	0.73
chr1_133735425_133736534	0.50	Mir6903	microRNA 6903	9334	0.14
chr10_29143400_29144848	0.44	Soga3	SOGA family member 3	65	0.5
chr3_30649995_30651146	0.44	Lrriq4	leucine-rich repeats and IQ motif containing 4	2684	0.17
chr1_184235265_184236073	0.41	Gm37223	predicted gene, 37223	122660	0.05
chr4_45824847_45825701	0.40	Igfbpl1	insulin-like growth factor binding protein-like 1	1649	0.31
chr12_29529828_29531185	0.38	Gm20208	predicted gene, 20208	609	0.74
chr3_108410436_108412210	0.38	Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2	4229	0.11
chr2_140666876_140668088	0.37	Flrt3	fibronectin leucine rich transmembrane protein 3	3918	0.37
chr13_112695809_112696082	0.37	Gm18883	predicted gene, 18883	3734	0.17
chr16_10446425_10446612	0.37	Tvp23a	trans-golgi network vesicle protein 23A	626	0.68
chr12_29528407_29529244	0.36	Myt1l	myelin transcription factor 1-like	424	0.85
chr4_89285170_89285321	0.35	Cdkn2a	cyclin dependent kinase inhibitor 2A	3053	0.2
chr9_35423074_35423780	0.34	Cdon	cell adhesion molecule-related/down-regulated by oncogenes	161	0.95
chr7_25294533_25294696	0.34	Cic	capicua transcriptional repressor	1594	0.18
chr14_122475443_122476757	0.34	Zic2	zinc finger protein of the cerebellum 2	665	0.44
chr7_44441951_44442938	0.33	Lrrc4b	leucine rich repeat containing 4B	41	0.93
chr3_34656299_34657721	0.33	Sox2ot	SOX2 overlapping transcript (non-protein coding)	974	0.4
chr1_42691569_42692627	0.33	Pantr1	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 1	995	0.42
chr3_94479508_94480443	0.33	Riiad1	regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1	366	0.63
chr12_12263781_12264571	0.32	Fam49a	family with sequence similarity 49, member A	1987	0.46
chr12_117157079_117158175	0.32	Gm10421	predicted gene 10421	5976	0.31
chr7_4920681_4922210	0.32	Nat14	N-acetyltransferase 14	583	0.48
chr17_46617075_46618033	0.32	Ptk7	PTK7 protein tyrosine kinase 7	11950	0.1
chrX_123943318_123943469	0.32	Rps12-ps20	ribosomal protein S12, pseudogene 20	13881	0.22
chr1_5916517_5917959	0.32	Npbwr1	neuropeptides B/W receptor 1	160	0.97
chr4_156183474_156184054	0.31	Agrn	agrin	2137	0.17
chr1_115684558_115685809	0.31	Cntnap5a	contactin associated protein-like 5A	427	0.58
chr6_121472423_121472626	0.31	Iqsec3	IQ motif and Sec7 domain 3	1099	0.53
chr5_120433178_120434996	0.31	Gm27199	predicted gene 27199	2320	0.19
chr12_33928070_33929277	0.31	Gm40383	predicted gene, 40383	217	0.53
chr4_96552598_96553907	0.31	Cyp2j6	cytochrome P450, family 2, subfamily j, polypeptide 6	409	0.87
chr8_94994139_94995207	0.30	Adgrg1	adhesion G protein-coupled receptor G1	77	0.95
chr3_114904046_114905354	0.30	Olfm3	olfactomedin 3	65	0.98
chr9_29943252_29944148	0.30	Ntm	neurotrimin	19419	0.28
chr10_80298461_80300404	0.30	Apc2	APC regulator of WNT signaling pathway 2	341	0.69
chr12_65428156_65429051	0.30	Gm26015	predicted gene, 26015	22633	0.22
chr3_26332588_26333347	0.29	Nlgn1	neuroligin 1	507	0.68
chr6_13835523_13837039	0.29	Gpr85	G protein-coupled receptor 85	960	0.59
chr15_95525022_95525792	0.29	Nell2	NEL-like 2	2771	0.35
chr6_90781027_90782541	0.29	Iqsec1	IQ motif and Sec7 domain 1	188	0.94
chr4_48586042_48586294	0.29	Tmeff1	transmembrane protein with EGF-like and two follistatin-like domains 1	617	0.75
chr7_126978893_126979102	0.28	Cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	764	0.32
chr8_41052368_41053980	0.28	Gm16193	predicted gene 16193	64	0.96
chr5_138278285_138278436	0.28	Gpc2	glypican 2 (cerebroglycan)	123	0.87
chr16_96280491_96281572	0.28	B3galt5	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5	233	0.93
chr14_76420544_76421824	0.27	Tsc22d1	TSC22 domain family, member 1	2356	0.39
chr18_15060980_15061427	0.27	Kctd1	potassium channel tetramerisation domain containing 1	686	0.74
chr9_97017174_97017806	0.27	Gm16010	predicted gene 16010	16	0.96
chr13_51566607_51568077	0.27	Shc3	src homology 2 domain-containing transforming protein C3	258	0.94
chr4_13746200_13747057	0.27	Runx1t1	RUNX1 translocation partner 1	3192	0.37
chr9_108824114_108825614	0.27	Gm35025	predicted gene, 35025	3	0.87
chr12_3370750_3371679	0.27	Gm48511	predicted gene, 48511	2785	0.18
chr1_6733530_6734383	0.27	St18	suppression of tumorigenicity 18	914	0.7
chr7_78884387_78884983	0.27	Mir7-2	microRNA 7-2	3592	0.14
chr10_60115211_60116020	0.27	Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2	9147	0.19
chr4_15880938_15882113	0.26	Calb1	calbindin 1	259	0.9
chr10_127268122_127269422	0.26	Dctn2	dynactin 2	2385	0.12
chr16_9994378_9995594	0.26	Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	63	0.98
chr2_166152712_166153273	0.26	Sulf2	sulfatase 2	1431	0.4
chr5_34182980_34183403	0.26	Mxd4	Max dimerization protein 4	1179	0.3
chr2_51144318_51145477	0.26	Rnd3	Rho family GTPase 3	4197	0.29
chr1_104768492_104769666	0.26	Cdh20	cadherin 20	550	0.79
chr3_34197711_34199105	0.26	Sox2ot	SOX2 overlapping transcript (non-protein coding)	1544	0.41
chr7_10480473_10481196	0.25	Gm30645	predicted gene, 30645	11141	0.11
chr5_148265188_148266164	0.25	Mtus2	microtubule associated tumor suppressor candidate 2	331	0.91
chr14_14345697_14346878	0.25	Il3ra	interleukin 3 receptor, alpha chain	12	0.94
chr11_69043818_69044451	0.25	Aurkb	aurora kinase B	1513	0.17
chr7_126277403_126277977	0.25	Sbk1	SH3-binding kinase 1	4290	0.14
chr10_3863416_3864702	0.25	Gm16149	predicted gene 16149	5548	0.21
chr19_4758474_4759201	0.25	Rbm4b	RNA binding motif protein 4B	1932	0.18
chr11_76466993_76468433	0.25	Abr	active BCR-related gene	585	0.77
chr11_57013425_57013750	0.25	Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	541	0.88
chr14_79773410_79774519	0.25	Pcdh8	protocadherin 8	2652	0.21
chr10_59950302_59950479	0.25	Ddit4	DNA-damage-inducible transcript 4	1444	0.4
chr2_20339506_20340619	0.25	Etl4	enhancer trap locus 4	238	0.94
chr8_121300864_121302289	0.24	Gm26815	predicted gene, 26815	55260	0.11
chr9_52145956_52147029	0.24	Zc3h12c	zinc finger CCCH type containing 12C	21619	0.17
chr2_65929929_65930575	0.24	Csrnp3	cysteine-serine-rich nuclear protein 3	115	0.97
chr4_82499658_82501360	0.24	Nfib	nuclear factor I/B	1193	0.5
chr12_117149811_117150131	0.24	Gm10421	predicted gene 10421	1244	0.61
chr13_51594475_51595717	0.24	Shc3	src homology 2 domain-containing transforming protein C3	25609	0.16
chr4_22835212_22836357	0.24	Gm24078	predicted gene, 24078	88653	0.09
chr14_14351494_14351697	0.24	Il3ra	interleukin 3 receptor, alpha chain	1974	0.2
chr15_92160888_92162023	0.24	Cntn1	contactin 1	98	0.98
chr14_68126289_68127413	0.23	Nefm	neurofilament, medium polypeptide	2005	0.3
chr7_133757893_133758428	0.23	Dhx32	DEAH (Asp-Glu-Ala-His) box polypeptide 32	1312	0.34
chr1_25832036_25832712	0.23	Gm9884	predicted gene 9884	1717	0.22
chr18_15060481_15060964	0.23	Kctd1	potassium channel tetramerisation domain containing 1	1167	0.55
chr7_67421454_67422158	0.23	Gm33926	predicted gene, 33926	22127	0.17
chr9_47533891_47534042	0.23	Cadm1	cell adhesion molecule 1	3593	0.24
chr11_64520049_64520796	0.23	Gm24275	predicted gene, 24275	70218	0.12
chr2_71536695_71536971	0.23	Dlx1as	distal-less homeobox 1, antisense	977	0.45
chr1_34677886_34678995	0.23	Arhgef4	Rho guanine nucleotide exchange factor (GEF) 4	252	0.89
chr2_167775422_167775573	0.23	Gm14321	predicted gene 14321	1970	0.27
chr2_80128704_80129752	0.23	Pde1a	phosphodiesterase 1A, calmodulin-dependent	230	0.94
chr14_28508967_28511864	0.23	Wnt5a	wingless-type MMTV integration site family, member 5A	203	0.89
chr3_31097203_31098928	0.23	Skil	SKI-like	1232	0.48
chr11_71749802_71749953	0.23	Wscd1	WSC domain containing 1	43	0.97
chr1_77503797_77505059	0.23	Mir6352	microRNA 6352	7660	0.19
chr7_81494043_81494194	0.23	Ap3b2	adaptor-related protein complex 3, beta 2 subunit	193	0.89
chr5_28466220_28467111	0.23	9530036O11Rik	RIKEN cDNA 9530036O11Rik	319	0.7
chr16_14906219_14907566	0.23	Efcab1	EF-hand calcium binding domain 1	227	0.95
chr4_41693576_41694021	0.23	Cntfr	ciliary neurotrophic factor receptor	1644	0.21
chr14_12339117_12339550	0.23	Gm24578	predicted gene, 24578	5429	0.13
chr13_105249326_105250833	0.23	Rnf180	ring finger protein 180	20960	0.22
chr12_5374545_5374864	0.23	Klhl29	kelch-like 29	978	0.45
chr10_19358667_19359238	0.23	Olig3	oligodendrocyte transcription factor 3	2419	0.35
chr4_72203288_72203508	0.22	C630043F03Rik	RIKEN cDNA C630043F03 gene	2050	0.31
chr17_35160468_35162406	0.22	Gm23442	predicted gene, 23442	1259	0.13
chr7_87586513_87587584	0.22	Grm5	glutamate receptor, metabotropic 5	2650	0.4
chr11_113621749_113621900	0.22	Sstr2	somatostatin receptor 2	2348	0.25
chr3_83768357_83769273	0.22	Sfrp2	secreted frizzled-related protein 2	1962	0.31
chr11_103776117_103777283	0.22	Wnt3	wingless-type MMTV integration site family, member 3	2550	0.24
chr7_16948034_16948663	0.22	Pnmal2	PNMA-like 2	3666	0.11
chr2_129908592_129909805	0.22	Gm28196	predicted gene 28196	39370	0.15
chr2_155514247_155515194	0.22	Ggt7	gamma-glutamyltransferase 7	128	0.92
chr11_88584998_88585279	0.22	Msi2	musashi RNA-binding protein 2	5009	0.28
chr8_109245493_109246323	0.22	D030068K23Rik	RIKEN cDNA D030068K23 gene	3958	0.33
chr1_131523488_131524457	0.22	Srgap2	SLIT-ROBO Rho GTPase activating protein 2	3375	0.18
chr3_55782570_55784448	0.22	Nbea	neurobeachin	19	0.96
chr12_27140199_27140495	0.22	Gm9866	predicted gene 9866	19964	0.27
chr17_93201490_93204144	0.22	Adcyap1	adenylate cyclase activating polypeptide 1	741	0.65
chr17_28256852_28257467	0.22	Ppard	peroxisome proliferator activator receptor delta	14549	0.11
chr1_166256819_166257273	0.22	Ildr2	immunoglobulin-like domain containing receptor 2	2853	0.25
chr12_91683421_91686419	0.22	Gm16876	predicted gene, 16876	255	0.86
chr5_98182267_98183697	0.21	Prdm8	PR domain containing 8	2004	0.26
chr3_87539034_87539185	0.21	ETV3L	ets variant 3-like	10990	0.16
chrX_134405492_134405850	0.21	Drp2	dystrophin related protein 2	869	0.59
chr7_79514267_79514939	0.21	Mir9-3hg	Mir9-3 host gene	629	0.46
chr5_5507730_5508026	0.21	Cldn12	claudin 12	6571	0.17
chr15_74563319_74564610	0.21	Adgrb1	adhesion G protein-coupled receptor B1	63	0.61
chrX_101708550_101709190	0.21	Gm9089	predicted gene 9089	691	0.52
chr9_78377654_78378912	0.21	Ooep	oocyte expressed protein	442	0.65
chr5_66967831_66968776	0.21	Limch1	LIM and calponin homology domains 1	113	0.93
chr8_58912073_58913264	0.21	Galntl6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6	28	0.88
chr2_120848173_120848373	0.21	Cdan1	congenital dyserythropoietic anemia, type I (human)	1855	0.22
chrX_96712746_96713886	0.21	Gpr165	G protein-coupled receptor 165	125	0.98
chr17_52600782_52601825	0.21	Gm27217	predicted gene 27217	1357	0.38
chr1_119420327_119420935	0.21	Inhbb	inhibin beta-B	1617	0.38
chr9_102721179_102722320	0.21	Amotl2	angiomotin-like 2	567	0.65
chr4_156182317_156182745	0.21	Agrn	agrin	3370	0.13
chr4_99118711_99119482	0.20	Dock7	dedicator of cytokinesis 7	1666	0.29
chr4_141998561_141998861	0.20	Fhad1	forkhead-associated (FHA) phosphopeptide binding domain 1	12926	0.12
chr9_48517322_48517969	0.20	Gm23653	predicted gene, 23653	10585	0.15
chrX_74310114_74310288	0.20	Gdi1	guanosine diphosphate (GDP) dissociation inhibitor 1	180	0.84
chr4_72195085_72196381	0.20	Tle1	transducin-like enhancer of split 1	3359	0.26
chr7_90886512_90887836	0.20	Gm45159	predicted gene 45159	102	0.88
chr16_22160432_22161001	0.20	Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	734	0.66
chr14_13283913_13285295	0.20	Gm5087	predicted gene 5087	26	0.69
chr2_151966993_151968089	0.20	Mir1953	microRNA 1953	76	0.96
chr9_87727084_87728023	0.20	D030062O11Rik	RIKEN cDNA D030062O11 gene	1732	0.31
chr9_29411568_29412757	0.20	Ntm	neurotrimin	42	0.99
chr15_100872381_100872532	0.20	Scn8a	sodium channel, voltage-gated, type VIII, alpha	1036	0.52
chr9_121493633_121494845	0.20	Cck	cholecystokinin	271	0.9
chr18_16804620_16805078	0.20	Cdh2	cadherin 2	3613	0.25
chr4_123001785_123002093	0.20	Mycl	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived	2600	0.21
chr12_3368013_3368276	0.20	Gm48511	predicted gene, 48511	285	0.85
chr2_38824726_38825619	0.20	Nr6a1os	nuclear receptor subfamily 6, group A, member 1, opposite strand	1831	0.22
chr19_55898749_55899177	0.20	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	654	0.79
chr3_89523444_89523616	0.20	Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	3366	0.2
chr1_56969244_56970464	0.20	Satb2	special AT-rich sequence binding protein 2	14	0.97
chr12_27334769_27335068	0.20	Sox11	SRY (sex determining region Y)-box 11	7656	0.29
chr17_8592901_8593278	0.20	Gm15425	predicted gene 15425	24229	0.18
chr8_70691465_70691881	0.20	Jund	jun D proto-oncogene	7276	0.08
chr15_101995407_101995688	0.20	Gm36026	predicted gene, 36026	8665	0.11
chr11_120045840_120045991	0.20	Aatk	apoptosis-associated tyrosine kinase	1155	0.3
chr6_144205160_144205647	0.20	Sox5	SRY (sex determining region Y)-box 5	976	0.71
chr16_81200177_81200598	0.20	Ncam2	neural cell adhesion molecule 2	310	0.93
chr9_123351055_123351227	0.20	Lars2	leucyl-tRNA synthetase, mitochondrial	15786	0.16
chr10_14759598_14760682	0.20	Nmbr	neuromedin B receptor	17	0.91
chr8_12915306_12916734	0.20	Mcf2l	mcf.2 transforming sequence-like	45	0.76
chr6_30957331_30957937	0.19	Klf14	Kruppel-like factor 14	1444	0.38
chr10_23345710_23346907	0.19	Eya4	EYA transcriptional coactivator and phosphatase 4	3579	0.36
chr19_55746711_55749175	0.19	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	5098	0.32
chr15_73839069_73840200	0.19	Mroh5	maestro heat-like repeat family member 5	37	0.97
chr11_87759834_87761999	0.19	Tspoap1	TSPO associated protein 1	329	0.75
chr9_52141326_52141501	0.19	Mir6244	microRNA 6244	25790	0.16
chr15_89840994_89842160	0.19	Syt10	synaptotagmin X	283	0.93
chr7_45802610_45802761	0.19	Cyth2	cytohesin 2	8203	0.07
chr1_77507828_77508329	0.19	Epha4	Eph receptor A4	7001	0.19
chr17_46976854_46977005	0.19	Ubr2	ubiquitin protein ligase E3 component n-recognin 2	24774	0.15
chr19_12488341_12489388	0.19	Dtx4	deltex 4, E3 ubiquitin ligase	12590	0.1
chr9_111352762_111353061	0.19	Trank1	tetratricopeptide repeat and ankyrin repeat containing 1	21909	0.18
chr1_151685824_151686091	0.19	Fam129a	family with sequence similarity 129, member A	8790	0.22
chr10_41715763_41715983	0.19	Ccdc162	coiled-coil domain containing 162	761	0.57
chr2_73572450_73573344	0.19	Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	7441	0.15
chr4_54945891_54946424	0.19	Zfp462	zinc finger protein 462	1109	0.63
chr2_4152602_4153854	0.19	Frmd4a	FERM domain containing 4A	356	0.79
chr2_164970287_164971705	0.19	Slc12a5	solute carrier family 12, member 5	2715	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	4.0	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.1	0.3	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.1	0.3	GO:0033058	directional locomotion(GO:0033058)
0.1	0.4	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
0.1	0.2	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1	0.2	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.3	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1	0.3	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.1	0.2	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.2	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.5	GO:0050957	equilibrioception(GO:0050957)
0.1	0.2	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.1	0.2	GO:2000041	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1	0.2	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.1	0.3	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.1	0.4	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.4	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.3	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.1	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.0	0.1	GO:1990123	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0	0.1	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0	0.1	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.0	0.1	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.0	0.7	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.1	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.2	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
0.0	0.2	GO:0030035	microspike assembly(GO:0030035)
0.0	0.1	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.3	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0	0.3	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.2	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.4	GO:0007614	short-term memory(GO:0007614)
0.0	0.2	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.1	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0	0.1	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.3	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.3	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:0010446	response to alkaline pH(GO:0010446)
0.0	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.2	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.2	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.1	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.1	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.2	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
0.0	0.1	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.1	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.0	0.1	GO:0016321	female meiosis chromosome segregation(GO:0016321)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.1	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.3	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.2	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.1	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.1	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.1	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.1	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0	0.1	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.1	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.0	0.1	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.2	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.2	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.0	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.0	GO:0072257	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.0	GO:0032346	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.3	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	0.0	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.0	GO:2000611	positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.1	GO:0015860	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0	0.1	GO:2001023	regulation of response to drug(GO:2001023)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.3	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0	0.1	GO:0061525	hindgut development(GO:0061525)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.0	GO:0048880	sensory system development(GO:0048880)
0.0	0.0	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.0	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.2	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.4	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.1	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.1	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	0.1	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0	0.1	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.0	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.0	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.0	0.1	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.0	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.0	0.1	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.2	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.0	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.0	0.1	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0	0.1	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.1	GO:0072174	metanephric tubule formation(GO:0072174)
0.0	0.0	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.1	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	0.1	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.0	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.0	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
0.0	0.0	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.1	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.0	GO:0030070	insulin processing(GO:0030070)
0.0	0.0	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.0	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.0	0.0	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.1	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.0	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.0	0.0	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.0	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.0	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.1	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.0	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.0	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.0	GO:1904938	dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.0	0.0	GO:0015817	histidine transport(GO:0015817)
0.0	0.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0046036	CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.2	GO:0043586	tongue development(GO:0043586)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.0	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.2	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.0	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	0.1	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.0	0.0	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.0	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.0	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0042891	antibiotic transport(GO:0042891)
0.0	0.0	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.0	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0060424	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0	0.0	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.0	0.0	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.1	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0001845	phagolysosome assembly(GO:0001845)
0.0	0.3	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.0	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:1901166	neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.0	GO:0031034	myosin filament assembly(GO:0031034)
0.0	0.0	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.1	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.0	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.2	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.0	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.0	GO:0046340	diacylglycerol catabolic process(GO:0046340)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0005861	troponin complex(GO:0005861)
0.1	0.3	GO:0097451	glial limiting end-foot(GO:0097451)
0.1	0.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	0.3	GO:0044308	axonal spine(GO:0044308)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:0044393	microspike(GO:0044393)
0.0	0.1	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0000802	transverse filament(GO:0000802)
0.0	0.3	GO:0097449	astrocyte projection(GO:0097449)
0.0	0.4	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.2	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.3	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.1	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0098651	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.2	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.4	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.1	GO:0001674	female germ cell nucleus(GO:0001674)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.0	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0043196	varicosity(GO:0043196)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0030172	troponin C binding(GO:0030172)
0.1	0.4	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.3	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.1	0.2	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.2	GO:0031014	troponin T binding(GO:0031014)
0.1	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0004946	bombesin receptor activity(GO:0004946)
0.1	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.1	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.6	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	3.9	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.5	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.3	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.4	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.3	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.1	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.5	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.5	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.0	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.2	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.0	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.0	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.1	PID FGF PATHWAY	FGF signaling pathway
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	PID IL3 PATHWAY	IL3-mediated signaling events
0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
1.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	REACTOME NEURONAL SYSTEM	Genes involved in Neuronal System
0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.6	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)