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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Foxd3

Z-value: 0.54

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Transcription factors associated with Foxd3

Gene Symbol	Gene ID	Gene Info
Foxd3 Ensembl NCBI MGI UniProt	ENSMUSG00000067261.3	forkhead box D3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr4_99655774_99658132	Foxd3	654	0.428084	0.44	4.8e-04	Click!

Activity of the Foxd3 motif across conditions

Conditions sorted by the z-value of the Foxd3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_59095360_59096062	1.08	Mia2	MIA SH3 domain ER export factor 2	88	0.93
chr6_37645617_37646179	1.02	Ybx1-ps2	Y box protein 1, pseudogene 2	41297	0.18
chr14_110753664_110754027	1.00	Slitrk6	SLIT and NTRK-like family, member 6	1304	0.42
chr11_96316025_96316970	0.99	Mir10a	microRNA 10a	668	0.4
chr17_75180734_75181322	0.97	Ltbp1	latent transforming growth factor beta binding protein 1	2117	0.38
chr2_74748525_74748913	0.95	Haglr	Hoxd antisense growth associated long non-coding RNA	1787	0.13
chr8_32004165_32004671	0.89	Nrg1	neuregulin 1	4688	0.33
chr6_137570111_137570964	0.89	Eps8	epidermal growth factor receptor pathway substrate 8	222	0.95
chr13_98691032_98691862	0.84	Tmem171	transmembrane protein 171	3321	0.18
chr13_17691689_17691840	0.79	Sugct	succinyl-CoA glutarate-CoA transferase	2972	0.18
chr18_11049995_11051717	0.79	Gata6os	GATA binding protein 6, opposite strand	631	0.64
chr12_31267815_31268221	0.77	Lamb1	laminin B1	2721	0.18
chr7_89405888_89406433	0.76	Fzd4	frizzled class receptor 4	1805	0.24
chr10_5287995_5289689	0.72	Gm23573	predicted gene, 23573	68331	0.12
chr18_43736152_43737245	0.69	Spink1	serine peptidase inhibitor, Kazal type 1	859	0.6
chr16_22160432_22161001	0.68	Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	734	0.66
chr5_101700539_101700765	0.68	9430085M18Rik	RIKEN cDNA 9430085M18 gene	2934	0.22
chr7_36694259_36694943	0.68	Gm38285	predicted gene, 38285	837	0.52
chr16_70798756_70798936	0.67	Gm49665	predicted gene, 49665	51124	0.17
chr7_131032170_131032380	0.66	Dmbt1	deleted in malignant brain tumors 1	206	0.95
chr10_69321361_69322099	0.64	Gm40685	predicted gene, 40685	9591	0.17
chr13_55923232_55923960	0.62	Gm47071	predicted gene, 47071	78669	0.07
chr14_74913536_74914053	0.61	Gm10847	predicted gene 10847	12651	0.19
chr10_116276295_116276851	0.61	Ptprb	protein tyrosine phosphatase, receptor type, B	1023	0.54
chr17_75437948_75438432	0.60	Rasgrp3	RAS, guanyl releasing protein 3	2264	0.4
chr4_53878509_53878668	0.58	Gm12468	predicted gene 12468	663	0.67
chr14_110753127_110753447	0.58	Slitrk6	SLIT and NTRK-like family, member 6	1862	0.32
chr1_184729275_184729496	0.57	Hlx	H2.0-like homeobox	2213	0.23
chr8_121129194_121129579	0.56	Foxl1	forkhead box L1	1446	0.3
chr12_57544414_57545119	0.56	Foxa1	forkhead box A1	1355	0.37
chr6_137935280_137935834	0.55	Gm24308	predicted gene, 24308	15586	0.26
chr15_103058659_103059955	0.55	5730585A16Rik	RIKEN cDNA 5730585A16 gene	1	0.95
chr8_47763533_47764764	0.54	Gm45824	predicted gene 45824	1977	0.21
chr9_60795900_60796901	0.54	Uaca	uveal autoantigen with coiled-coil domains and ankyrin repeats	1775	0.35
chr4_84768134_84768574	0.53	Gm12415	predicted gene 12415	26879	0.21
chr10_116275477_116276105	0.52	Ptprb	protein tyrosine phosphatase, receptor type, B	241	0.93
chr17_88628874_88630550	0.52	Ston1	stonin 1	2348	0.25
chr15_51274333_51274786	0.51	Gm19303	predicted gene, 19303	121051	0.06
chr8_33905601_33906425	0.50	Rbpms	RNA binding protein gene with multiple splicing	14249	0.16
chr17_78205213_78205510	0.50	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	4296	0.17
chr6_142570795_142570980	0.50	Kcnj8	potassium inwardly-rectifying channel, subfamily J, member 8	484	0.82
chr17_79261126_79261277	0.49	Gm5230	predicted gene 5230	3152	0.32
chr4_140003980_140005143	0.48	Klhdc7a	kelch domain containing 7A	36535	0.13
chr2_156047784_156048442	0.47	Fer1l4	fer-1-like 4 (C. elegans)	4834	0.1
chr9_77044031_77044308	0.47	Tinag	tubulointerstitial nephritis antigen	1580	0.34
chr7_143086048_143086508	0.47	Trpm5	transient receptor potential cation channel, subfamily M, member 5	851	0.44
chr5_139598854_139600619	0.46	Uncx	UNC homeobox	55838	0.1
chr13_48543356_48543507	0.46	Gm37238	predicted gene, 37238	1602	0.19
chr16_34999592_34999743	0.46	Mylk	myosin, light polypeptide kinase	4860	0.18
chr11_30195109_30195350	0.46	Sptbn1	spectrin beta, non-erythrocytic 1	3028	0.33
chr6_100195944_100196095	0.45	Rybp	RING1 and YY1 binding protein	37112	0.14
chr18_83984951_83985102	0.45	Gm50421	predicted gene, 50421	2969	0.31
chr12_80123554_80123705	0.45	2310015A10Rik	RIKEN cDNA 2310015A10 gene	2490	0.19
chr10_99618893_99619600	0.44	Gm20110	predicted gene, 20110	10075	0.17
chr2_170139645_170139884	0.44	Zfp217	zinc finger protein 217	2914	0.38
chr13_71951907_71952058	0.43	Gm40999	predicted gene, 40999	4570	0.27
chr3_145101984_145102292	0.43	Clca2	chloride channel accessory 2	2695	0.28
chr15_101139509_101140276	0.43	Acvrl1	activin A receptor, type II-like 1	2292	0.19
chr2_125154199_125154495	0.43	Slc12a1	solute carrier family 12, member 1	1747	0.28
chr12_37112722_37113009	0.42	Meox2	mesenchyme homeobox 2	4325	0.22
chr2_170075358_170075771	0.42	Zfp217	zinc finger protein 217	55656	0.15
chr19_46532996_46533147	0.42	Arl3	ADP-ribosylation factor-like 3	9742	0.14
chr19_46570976_46571127	0.41	Arl3	ADP-ribosylation factor-like 3	2025	0.23
chr1_155809619_155810012	0.41	Qsox1	quiescin Q6 sulfhydryl oxidase 1	3005	0.17
chr10_97566192_97567945	0.41	Lum	lumican	1940	0.32
chr5_28462243_28464057	0.41	9530036O11Rik	RIKEN cDNA 9530036O11Rik	3834	0.23
chr9_77464536_77464687	0.40	Lrrc1	leucine rich repeat containing 1	22120	0.17
chr1_171446655_171447030	0.40	F11r	F11 receptor	9263	0.09
chr6_99275359_99276069	0.39	Foxp1	forkhead box P1	9182	0.29
chr10_97479376_97480642	0.39	Dcn	decorin	400	0.88
chr19_25381686_25382798	0.39	Kank1	KN motif and ankyrin repeat domains 1	13061	0.21
chr16_26103797_26103994	0.39	P3h2	prolyl 3-hydroxylase 2	1889	0.46
chr5_47988429_47989444	0.39	Slit2	slit guidance ligand 2	1094	0.46
chr13_89585655_89585816	0.39	Hapln1	hyaluronan and proteoglycan link protein 1	1224	0.51
chr18_61954762_61955556	0.39	Sh3tc2	SH3 domain and tetratricopeptide repeats 2	2075	0.33
chr18_56649239_56649419	0.38	Gm50289	predicted gene, 50289	18449	0.14
chr9_31688091_31688790	0.38	Gm47436	predicted gene, 47436	10414	0.21
chr1_162220626_162221297	0.38	Dnm3os	dynamin 3, opposite strand	1093	0.42
chr18_90002590_90002741	0.38	Gm6173	predicted gene 6173	16414	0.25
chr10_44525081_44525285	0.38	Prdm1	PR domain containing 1, with ZNF domain	3318	0.22
chr11_96292706_96294113	0.38	Hoxb6	homeobox B6	933	0.29
chr9_70241032_70241795	0.37	Myo1e	myosin IE	34045	0.17
chr2_74707355_74707963	0.37	Hoxd8	homeobox D8	2507	0.08
chr12_98683337_98683705	0.37	Ptpn21	protein tyrosine phosphatase, non-receptor type 21	229	0.9
chr9_92694521_92694861	0.37	Gm29396	predicted gene 29396	2748	0.29
chrX_146014065_146014216	0.37	Gm6447	predicted gene 6447	19849	0.18
chrX_120591703_120591854	0.37	Gm14930	predicted gene 14930	149092	0.04
chr12_35533032_35533561	0.37	Gm48236	predicted gene, 48236	1125	0.37
chr10_5594267_5594984	0.37	Myct1	myc target 1	850	0.67
chr6_52172116_52173481	0.36	Gm15050	predicted gene 15050	83	0.89
chr6_99517992_99518143	0.36	Foxp1	forkhead box P1	2930	0.29
chr13_111326182_111326588	0.36	Gm15285	predicted gene 15285	35290	0.13
chr2_32908170_32908947	0.35	Fam129b	family with sequence similarity 129, member B	2350	0.19
chr2_125282385_125283036	0.35	Gm14003	predicted gene 14003	1268	0.44
chr2_36233437_36233701	0.35	Ptgs1	prostaglandin-endoperoxide synthase 1	2680	0.17
chr15_83530746_83530897	0.34	Bik	BCL2-interacting killer	2723	0.16
chr10_121982673_121982824	0.34	Srgap1	SLIT-ROBO Rho GTPase activating protein 1	64560	0.09
chr5_139548537_139550176	0.34	Uncx	UNC homeobox	5458	0.19
chr18_84077214_84077748	0.34	Tshz1	teashirt zinc finger family member 1	7594	0.17
chrX_82950582_82950733	0.34	Dmd	dystrophin, muscular dystrophy	1754	0.53
chr19_55102740_55102891	0.33	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	276	0.91
chr15_82793644_82794188	0.33	Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	306	0.81
chr15_3580312_3581004	0.33	Ghr	growth hormone receptor	1184	0.57
chr5_113799288_113800716	0.33	Tmem119	transmembrane protein 119	444	0.69
chr6_141380917_141381972	0.33	Gm10400	predicted gene 10400	40891	0.17
chr7_135526475_135527168	0.33	Clrn3	clarin 3	1833	0.31
chr16_40048843_40048994	0.32	Lsamp	limbic system-associated membrane protein	64323	0.13
chr12_110488357_110488534	0.32	Gm19605	predicted gene, 19605	2237	0.25
chr9_43231799_43232208	0.32	Oaf	out at first homolog	6911	0.15
chr2_68435653_68436705	0.32	Stk39	serine/threonine kinase 39	35761	0.16
chr6_101374596_101375205	0.32	Pdzrn3	PDZ domain containing RING finger 3	2442	0.26
chr5_24725084_24725454	0.32	Wdr86	WD repeat domain 86	5411	0.15
chr9_61366071_61366222	0.32	Gm10655	predicted gene 10655	5481	0.2
chr2_169741294_169741445	0.31	Tshz2	teashirt zinc finger family member 2	107693	0.07
chr1_184675496_184676152	0.31	Gm38358	predicted gene, 38358	19210	0.14
chr8_11309999_11311023	0.31	Col4a1	collagen, type IV, alpha 1	2178	0.24
chr7_112498586_112498737	0.31	Parva	parvin, alpha	21040	0.2
chr2_110360491_110361293	0.31	Fibin	fin bud initiation factor homolog (zebrafish)	2291	0.34
chr4_153018259_153019185	0.31	Gm25779	predicted gene, 25779	5138	0.33
chr15_84812976_84813127	0.31	Phf21b	PHD finger protein 21B	9494	0.17
chr19_10699827_10700127	0.31	Vps37c	vacuolar protein sorting 37C	11212	0.1
chr11_35544219_35545325	0.31	Slit3	slit guidance ligand 3	87	0.98
chr2_160620140_160620291	0.30	Gm14221	predicted gene 14221	244	0.91
chr15_8967409_8968940	0.30	Ranbp3l	RAN binding protein 3-like	172	0.96
chr4_118583799_118583950	0.30	Cfap57	cilia and flagella associated protein 57	36531	0.08
chr5_124204256_124204407	0.30	Pitpnm2os2	phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 2	8689	0.12
chr14_45511039_45511190	0.30	Fermt2	fermitin family member 2	7826	0.11
chr6_4953094_4953370	0.29	Gm26556	predicted gene, 26556	5751	0.16
chr11_58380480_58380717	0.29	Lypd8	LY6/PLAUR domain containing 8	1555	0.22
chr7_120916926_120917434	0.29	Polr3e	polymerase (RNA) III (DNA directed) polypeptide E	564	0.66
chr2_115856008_115856929	0.29	Meis2	Meis homeobox 2	12399	0.29
chr5_147292277_147292672	0.29	Mir7k	microRNA 7k	9176	0.1
chr6_52182052_52182511	0.29	Gm29430	predicted gene 29430	829	0.26
chr6_129183729_129184848	0.29	Clec2d	C-type lectin domain family 2, member d	3673	0.14
chr8_26329826_26330767	0.29	Gm31784	predicted gene, 31784	17962	0.15
chr2_126556967_126557245	0.28	Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	978	0.57
chr6_13193034_13193185	0.28	Vwde	von Willebrand factor D and EGF domains	15434	0.23
chr19_20602564_20602913	0.28	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	777	0.68
chr8_108104785_108105045	0.28	Zfhx3	zinc finger homeobox 3	110356	0.07
chr9_96885174_96885371	0.28	Pxylp1	2-phosphoxylose phosphatase 1	4141	0.18
chr10_80330985_80331440	0.28	Reep6	receptor accessory protein 6	1010	0.24
chr1_74964735_74965250	0.28	Gm37744	predicted gene, 37744	10740	0.12
chr14_16572461_16573738	0.28	Rarb	retinoic acid receptor, beta	1946	0.34
chr10_75930797_75931493	0.28	Mmp11	matrix metallopeptidase 11	1330	0.2
chr4_118487482_118487969	0.28	Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	2030	0.19
chr4_45965494_45966277	0.27	Tdrd7	tudor domain containing 7	551	0.79
chr14_44863488_44863639	0.27	Ptgdr	prostaglandin D receptor	4188	0.12
chr6_100525882_100526106	0.27	1700049E22Rik	RIKEN cDNA 1700049E22 gene	1406	0.41
chr16_14710279_14710697	0.27	Snai2	snail family zinc finger 2	4636	0.28
chr12_39741189_39741358	0.27	Gm18116	predicted gene, 18116	23913	0.23
chr8_106521568_106521719	0.27	Cdh3	cadherin 3	10752	0.17
chr5_17642536_17642831	0.27	Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	51519	0.17
chr3_60529662_60530216	0.27	Mbnl1	muscleblind like splicing factor 1	308	0.91
chr2_148043571_148045987	0.27	Foxa2	forkhead box A2	685	0.65
chr9_97276072_97276223	0.27	A030012G06Rik	RIKEN cDNA A030012G06 gene	13039	0.17
chr9_31911798_31912140	0.27	Barx2	BarH-like homeobox 2	1493	0.35
chr9_114560970_114561936	0.27	Trim71	tripartite motif-containing 71	2916	0.23
chr7_70369044_70370707	0.27	Nr2f2	nuclear receptor subfamily 2, group F, member 2	3140	0.16
chr14_20699000_20699218	0.27	Gm25328	predicted gene, 25328	2414	0.11
chr8_41015082_41015919	0.27	Mtus1	mitochondrial tumor suppressor 1	820	0.53
chr2_166030364_166031781	0.26	Ncoa3	nuclear receptor coactivator 3	16846	0.15
chr13_38126437_38126720	0.26	Dsp	desmoplakin	24716	0.14
chr10_79531492_79531759	0.26	Mir6909	microRNA 6909	535	0.64
chr9_58346541_58346692	0.26	Tbc1d21	TBC1 domain family, member 21	23753	0.13
chr16_21818680_21818960	0.26	Map3k13	mitogen-activated protein kinase kinase kinase 13	7122	0.12
chr12_111911009_111911160	0.26	Ppp1r13b	protein phosphatase 1, regulatory subunit 13B	2974	0.16
chr4_116144678_116144948	0.26	Lurap1	leucine rich adaptor protein 1	204	0.88
chr3_146946599_146946750	0.26	Ttll7	tubulin tyrosine ligase-like family, member 7	2754	0.35
chr18_54452409_54453689	0.26	Gm50361	predicted gene, 50361	23716	0.19
chr7_12809561_12809753	0.26	Zfp329	zinc finger protein 329	1582	0.17
chr4_8237536_8238080	0.26	Car8	carbonic anhydrase 8	1233	0.46
chr15_38567059_38567529	0.25	Gm29697	predicted gene, 29697	6702	0.13
chr5_92899429_92899666	0.25	Shroom3	shroom family member 3	1554	0.45
chr17_67351548_67352402	0.25	Ptprm	protein tyrosine phosphatase, receptor type, M	2098	0.47
chr1_153279868_153280137	0.25	Gm38009	predicted gene, 38009	7188	0.18
chr2_103298575_103299104	0.25	Ehf	ets homologous factor	726	0.68
chr7_46029818_46030744	0.25	Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	21	0.96
chr12_75537153_75537454	0.25	Ppp2r5e	protein phosphatase 2, regulatory subunit B', epsilon	12371	0.19
chr9_19125111_19125262	0.25	Olfr836	olfactory receptor 836	4229	0.16
chr11_112708652_112709267	0.25	BC006965	cDNA sequence BC006965	1963	0.44
chr3_24573795_24573946	0.25	Gm24704	predicted gene, 24704	11796	0.31
chrX_122831261_122831412	0.25	Gm14940	predicted gene 14940	62467	0.15
chr2_4588036_4588187	0.25	Gm13179	predicted gene 13179	824	0.64
chr14_105744608_105744759	0.25	Gm10076	predicted gene 10076	62854	0.1
chr16_87716187_87716338	0.25	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	17258	0.2
chr4_83050103_83050875	0.24	Frem1	Fras1 related extracellular matrix protein 1	1678	0.41
chr8_108701364_108702549	0.24	Zfhx3	zinc finger homeobox 3	1144	0.58
chr3_123984120_123984365	0.24	Gm15399	predicted gene 15399	862	0.74
chr13_25083128_25083551	0.24	Dcdc2a	doublecortin domain containing 2a	13008	0.18
chr11_96321472_96321760	0.24	Hoxb3	homeobox B3	1710	0.14
chr10_99912846_99913873	0.24	Gm47579	predicted gene, 47579	47339	0.13
chrX_36587406_36587686	0.24	Pgrmc1	progesterone receptor membrane component 1	10660	0.2
chr4_135254409_135255495	0.24	Clic4	chloride intracellular channel 4 (mitochondrial)	17862	0.14
chr10_115817324_115818606	0.24	Tspan8	tetraspanin 8	681	0.78
chr2_37742222_37742373	0.24	Crb2	crumbs family member 2	33952	0.13
chr4_118691378_118691529	0.24	Olfr1342	olfactory receptor 1342	990	0.36
chr5_124892161_124892312	0.24	Zfp664	zinc finger protein 664	7667	0.19
chr16_4644396_4644547	0.24	Coro7	coronin 7	2245	0.18
chr17_56277120_56277484	0.24	Ticam1	toll-like receptor adaptor molecule 1	516	0.61
chr6_99095299_99096526	0.23	Foxp1	forkhead box P1	293	0.93

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.2	0.5	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.2	0.6	GO:0060005	vestibular reflex(GO:0060005)
0.1	0.5	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1	0.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	0.3	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1	0.4	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	0.3	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.2	GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1	0.2	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.1	0.2	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.3	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.1	0.2	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.3	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.3	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.1	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0060459	left lung development(GO:0060459)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.2	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.3	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.1	GO:0071476	cellular hypotonic response(GO:0071476)
0.0	0.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	1.1	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.2	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.0	0.1	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.0	0.2	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.2	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:1903012	positive regulation of bone development(GO:1903012)
0.0	0.2	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.1	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.2	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.2	GO:0035826	rubidium ion transport(GO:0035826)
0.0	0.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.0	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.0	0.1	GO:0072008	glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0	0.2	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.0	0.1	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.0	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0051794	regulation of catagen(GO:0051794)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.1	GO:0032905	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0	0.0	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.0	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	0.1	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.1	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.0	0.3	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.4	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.0	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0035811	negative regulation of urine volume(GO:0035811)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.0	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.3	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.0	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.3	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.1	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.0	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.0	GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.1	GO:0097460	ferrous iron import into cell(GO:0097460)
0.0	0.1	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.0	0.1	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.0	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.0	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0	0.0	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.0	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.0	GO:0048619	hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619)
0.0	0.1	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.0	GO:0015684	ferrous iron transport(GO:0015684)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.4	GO:0009268	response to pH(GO:0009268)
0.0	0.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.0	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.1	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.0	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.0	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.1	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.6	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	1.1	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.5	GO:0001527	microfibril(GO:0001527)
0.0	0.7	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.1	GO:0032437	cuticular plate(GO:0032437)
0.0	0.1	GO:0097342	ripoptosome(GO:0097342)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0033391	chromatoid body(GO:0033391)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.4	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.0	GO:0005767	secondary lysosome(GO:0005767)
0.0	0.0	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.0	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.3	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.3	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.3	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1	0.2	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.4	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.9	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.2	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.0	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.0	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	1.1	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.0	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	1.1	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint

Results for Foxd3

Z-value: 0.54

Motif logo

Transcription factors associated with Foxd3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Foxd3 motif across conditions

Conditions sorted by the z-value of the Foxd3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: