Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Foxf1

Z-value: 1.27

Motif logo

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Transcription factors associated with Foxf1

Gene Symbol Gene ID Gene Info
ENSMUSG00000042812.4 Foxf1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Foxf1chr8_121082801_1210855312200.7134490.435.4e-04Click!

Activity of the Foxf1 motif across conditions

Conditions sorted by the z-value of the Foxf1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_120022870_120023448 4.16 Xirp1
xin actin-binding repeat containing 1
439
0.69
chr15_25941347_25942080 3.99 Retreg1
reticulophagy regulator 1
826
0.63
chr18_65393136_65393441 3.37 Alpk2
alpha-kinase 2
606
0.6
chr5_17848825_17849185 3.33 Cd36
CD36 molecule
724
0.8
chr11_18872620_18872876 2.95 8430419K02Rik
RIKEN cDNA 8430419K02 gene
593
0.71
chr14_26442242_26442821 2.95 Slmap
sarcolemma associated protein
124
0.96
chr1_43196103_43196958 2.94 Fhl2
four and a half LIM domains 2
231
0.93
chr9_101198368_101199080 2.74 Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
127
0.94
chr10_13093078_13094452 2.71 Plagl1
pleiomorphic adenoma gene-like 1
2752
0.29
chr8_45658542_45659771 2.65 Sorbs2
sorbin and SH3 domain containing 2
352
0.89
chr8_33927475_33928014 2.58 Rbpms
RNA binding protein gene with multiple splicing
1532
0.38
chr11_86584054_86584708 2.56 Mir21a
microRNA 21a
223
0.9
chr6_71261026_71261496 2.53 Smyd1
SET and MYND domain containing 1
971
0.38
chr11_85833878_85836704 2.51 Tbx2
T-box 2
2740
0.17
chr3_137341050_137342448 2.44 Emcn
endomucin
575
0.82
chr2_14607282_14607589 2.35 Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
2313
0.18
chr11_111583176_111584131 2.34 Gm11676
predicted gene 11676
29653
0.25
chr7_48847211_48847926 2.33 Csrp3
cysteine and glycine-rich protein 3
465
0.76
chr19_53679904_53680339 2.32 Rbm20
RNA binding motif protein 20
2815
0.26
chr12_117657998_117660727 2.26 Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
1328
0.51
chr9_101196118_101196470 2.24 Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
2557
0.18
chr8_121088119_121090419 2.21 Gm27530
predicted gene, 27530
4563
0.13
chr11_17460099_17460867 2.19 Gm12015
predicted gene 12015
162064
0.03
chr10_99912846_99913873 2.17 Gm47579
predicted gene, 47579
47339
0.13
chr9_101196473_101196755 2.14 Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
2237
0.2
chr1_51288641_51290950 2.13 Cavin2
caveolae associated 2
669
0.72
chr15_25942778_25943455 2.11 Retreg1
reticulophagy regulator 1
437
0.83
chr7_65368712_65369714 2.09 Tjp1
tight junction protein 1
1802
0.31
chr13_32965217_32966457 2.05 Serpinb6b
serine (or cysteine) peptidase inhibitor, clade B, member 6b
334
0.84
chr2_114051146_114052179 2.04 Actc1
actin, alpha, cardiac muscle 1
1225
0.4
chr10_69136095_69136349 2.03 Gm24172
predicted gene, 24172
3340
0.21
chr1_51294105_51294669 2.03 Cavin2
caveolae associated 2
5261
0.21
chr2_80037645_80038971 2.03 Pde1a
phosphodiesterase 1A, calmodulin-dependent
721
0.79
chr6_21822751_21823961 2.01 Tspan12
tetraspanin 12
28472
0.16
chrX_6578805_6579490 1.99 Shroom4
shroom family member 4
1861
0.5
chr19_57890092_57890518 1.97 Mir5623
microRNA 5623
160862
0.04
chr8_45887181_45888227 1.96 Pdlim3
PDZ and LIM domain 3
2184
0.22
chr17_17448568_17449744 1.96 Lix1
limb and CNS expressed 1
336
0.88
chr16_38363311_38363597 1.95 Popdc2
popeye domain containing 2
1209
0.35
chr3_125591549_125592080 1.93 Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
89173
0.1
chr6_138708519_138709263 1.90 Igbp1b
immunoglobulin (CD79A) binding protein 1b
50347
0.16
chr17_79451074_79451933 1.90 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
96412
0.07
chr12_118560311_118560462 1.89 D230030E09Rik
Riken cDNA D230030E09 gene
30193
0.18
chr6_119194389_119194967 1.88 Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
1553
0.37
chr4_98727774_98728475 1.87 L1td1
LINE-1 type transposase domain containing 1
1331
0.39
chr1_23264366_23264708 1.86 Mir30a
microRNA 30a
7732
0.12
chr9_43107052_43107380 1.85 Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
23
0.98
chr11_19009505_19011164 1.84 Gm16140
predicted gene 16140
1204
0.32
chr16_34261892_34262050 1.84 Kalrn
kalirin, RhoGEF kinase
868
0.75
chr9_67046002_67046745 1.83 Tpm1
tropomyosin 1, alpha
2411
0.27
chr18_10787357_10787713 1.83 Mir133a-1hg
Mir133a-1, Mir1b and Mir1a-2 host gene
1652
0.2
chr4_83050960_83052655 1.80 Frem1
Fras1 related extracellular matrix protein 1
360
0.89
chr10_102513522_102514467 1.79 Rassf9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
1738
0.36
chr5_100259261_100259598 1.79 2310034O05Rik
RIKEN cDNA 2310034O05 gene
48721
0.11
chr18_68966368_68966646 1.77 4930546C10Rik
RIKEN cDNA 4930546C10 gene
14979
0.24
chr14_101843911_101844062 1.77 Lmo7
LIM domain only 7
3167
0.34
chr14_63235525_63236294 1.73 Gata4
GATA binding protein 4
9339
0.17
chr1_45312046_45312607 1.73 Gm47302
predicted gene, 47302
653
0.46
chr2_72054427_72054758 1.71 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
12
0.98
chr3_115710711_115712215 1.71 S1pr1
sphingosine-1-phosphate receptor 1
3609
0.24
chr13_106835269_106836682 1.70 Lrrc70
leucine rich repeat containing 70
173
0.7
chr5_83352776_83353067 1.70 Tecrl
trans-2,3-enoyl-CoA reductase-like
2035
0.43
chr14_57344799_57345345 1.69 Gm23593
predicted gene, 23593
11587
0.15
chr16_37777737_37778273 1.68 Fstl1
follistatin-like 1
853
0.63
chr18_58557873_58558723 1.68 Slc27a6
solute carrier family 27 (fatty acid transporter), member 6
2041
0.43
chr2_167239298_167240893 1.68 Ptgis
prostaglandin I2 (prostacyclin) synthase
494
0.75
chrX_106840356_106840805 1.68 Rtl3
retrotransposon Gag like 3
64
0.97
chr6_5494856_5495620 1.67 Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
1023
0.67
chr2_44978810_44979253 1.64 Zeb2
zinc finger E-box binding homeobox 2
43884
0.14
chr17_26844031_26845183 1.64 Nkx2-5
NK2 homeobox 5
402
0.75
chr15_98377565_98377733 1.63 Olfr283
olfactory receptor 283
1548
0.24
chr15_80010959_80011742 1.62 Gm41361
predicted gene, 41361
981
0.36
chr9_92276388_92276986 1.61 Plscr2
phospholipid scramblase 2
941
0.48
chr13_12101498_12102642 1.61 Ryr2
ryanodine receptor 2, cardiac
4389
0.22
chr1_83345373_83345573 1.61 Gm37517
predicted gene, 37517
12887
0.18
chr17_26868575_26869203 1.60 Gm20468
predicted gene 20468
7468
0.1
chr6_21226614_21227216 1.60 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
11412
0.24
chr10_61977984_61979348 1.60 Col13a1
collagen, type XIII, alpha 1
407
0.84
chr13_109261723_109262640 1.59 Pde4d
phosphodiesterase 4D, cAMP specific
1527
0.55
chr13_90012041_90013007 1.59 Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
76558
0.09
chr15_11907838_11908523 1.58 Npr3
natriuretic peptide receptor 3
893
0.51
chr9_90055154_90055692 1.57 Ctsh
cathepsin H
864
0.58
chr10_58396489_58397099 1.56 Lims1
LIM and senescent cell antigen-like domains 1
2406
0.3
chr11_36486059_36486531 1.56 Tenm2
teneurin transmembrane protein 2
8844
0.32
chr7_98678348_98678798 1.55 Gm45132
predicted gene 45132
2074
0.24
chr2_72203811_72204385 1.55 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
5299
0.2
chr10_38968014_38968667 1.54 Lama4
laminin, alpha 4
2668
0.33
chr5_136427282_136427433 1.54 Mir721
microRNA 721
51554
0.11
chr10_53337221_53337426 1.54 Pln
phospholamban
344
0.82
chr8_41015082_41015919 1.53 Mtus1
mitochondrial tumor suppressor 1
820
0.53
chr1_168426195_168428871 1.53 Pbx1
pre B cell leukemia homeobox 1
3971
0.3
chr5_119673183_119673803 1.53 Tbx3
T-box 3
1952
0.23
chrX_82949777_82950054 1.53 Dmd
dystrophin, muscular dystrophy
1012
0.71
chr3_30106536_30107229 1.50 Mecom
MDS1 and EVI1 complex locus
33541
0.17
chr1_23271255_23272383 1.50 Mir30a
microRNA 30a
450
0.73
chr17_43390382_43390611 1.50 Adgrf5
adhesion G protein-coupled receptor F5
1008
0.62
chr12_73012750_73012901 1.48 Six1
sine oculis-related homeobox 1
29990
0.15
chr9_25201672_25202276 1.48 Gm8031
predicted gene 8031
27095
0.14
chr15_25364028_25365185 1.48 4930445E18Rik
RIKEN cDNA 4930445E18 gene
31947
0.14
chr10_116276295_116276851 1.48 Ptprb
protein tyrosine phosphatase, receptor type, B
1023
0.54
chr18_41860653_41861741 1.47 Gm50410
predicted gene, 50410
13637
0.22
chr6_48739497_48740057 1.47 Gimap1
GTPase, IMAP family member 1
670
0.27
chr1_187910901_187911320 1.47 Esrrg
estrogen-related receptor gamma
86717
0.09
chr10_3368375_3368998 1.46 Ppp1r14c
protein phosphatase 1, regulatory inhibitor subunit 14C
2142
0.36
chr8_33925892_33926043 1.45 Rbpms
RNA binding protein gene with multiple splicing
3309
0.23
chr17_48096260_48098177 1.44 Gm49946
predicted gene, 49946
4439
0.13
chr9_24769617_24771807 1.43 Tbx20
T-box 20
962
0.56
chr5_104113204_104114091 1.43 Sparcl1
SPARC-like 1
86
0.71
chr9_24772390_24773199 1.42 Tbx20
T-box 20
1490
0.39
chr3_41522196_41522994 1.42 2400006E01Rik
RIKEN cDNA 2400006E01 gene
622
0.65
chr7_112225854_112227329 1.41 Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
701
0.78
chr11_72409443_72409692 1.41 Smtnl2
smoothelin-like 2
2144
0.21
chr12_106378438_106379564 1.40 Gm17032
predicted gene 17032
51633
0.13
chr4_127311434_127313205 1.40 Gja4
gap junction protein, alpha 4
1720
0.26
chr3_142496513_142497790 1.39 Gbp5
guanylate binding protein 5
209
0.93
chr1_112456627_112457016 1.39 Gm22331
predicted gene, 22331
11090
0.28
chr6_142701786_142702806 1.39 Abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
19
0.98
chr8_119844749_119844973 1.39 Cotl1
coactosin-like 1 (Dictyostelium)
4317
0.19
chrX_96456094_96457321 1.39 Heph
hephaestin
279
0.62
chr4_48754722_48754946 1.38 Gm24573
predicted gene, 24573
8128
0.2
chr12_73913244_73913533 1.38 Hif1a
hypoxia inducible factor 1, alpha subunit
5484
0.17
chr2_35431827_35432962 1.38 Ggta1
glycoprotein galactosyltransferase alpha 1, 3
239
0.89
chr11_18754415_18755437 1.38 Gm28401
predicted gene 28401
1812
0.33
chr10_93446886_93447075 1.38 Lta4h
leukotriene A4 hydrolase
6431
0.16
chr13_74120960_74122199 1.37 Slc9a3
solute carrier family 9 (sodium/hydrogen exchanger), member 3
64
0.97
chr2_105122763_105123433 1.37 Wt1os
Wilms tumor 1 homolog, opposite strand
3305
0.21
chr11_46057942_46058389 1.36 Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
2107
0.23
chr9_77637137_77637792 1.36 Klhl31
kelch-like 31
964
0.54
chr16_85549016_85550538 1.36 Cyyr1
cysteine and tyrosine-rich protein 1
640
0.75
chr2_84423814_84425562 1.36 Calcrl
calcitonin receptor-like
578
0.75
chr10_53338934_53339122 1.36 Pln
phospholamban
1323
0.32
chr14_63234859_63235070 1.36 Gata4
GATA binding protein 4
10284
0.17
chr5_75539140_75539420 1.35 Gm24502
predicted gene, 24502
21870
0.19
chr4_150937866_150938220 1.35 Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
8246
0.15
chr4_13833042_13833616 1.34 Runx1t1
RUNX1 translocation partner 1
48547
0.18
chr6_48676737_48676890 1.34 Gimap9
GTPase, IMAP family member 9
684
0.43
chr8_89726781_89726932 1.34 Gm24212
predicted gene, 24212
59552
0.16
chr1_187999444_187999905 1.34 Esrrg
estrogen-related receptor gamma
1806
0.42
chr5_74197172_74198949 1.34 Rasl11b
RAS-like, family 11, member B
169
0.94
chr14_103679657_103680888 1.34 Slain1
SLAIN motif family, member 1
15774
0.19
chr12_9580218_9581715 1.34 Osr1
odd-skipped related transcription factor 1
6525
0.19
chr2_76804052_76804549 1.34 Ttn
titin
22242
0.22
chr12_34527603_34529023 1.34 Hdac9
histone deacetylase 9
9
0.99
chr5_104111427_104113181 1.33 Sparcl1
SPARC-like 1
1135
0.33
chr9_67670151_67670404 1.33 Gm47110
predicted gene, 47110
29904
0.15
chr1_40224749_40225907 1.33 Il1r1
interleukin 1 receptor, type I
248
0.93
chr14_121697242_121698803 1.32 Dock9
dedicator of cytokinesis 9
395
0.9
chr1_91054645_91055420 1.32 Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
1446
0.43
chr3_152262616_152262926 1.32 Nexn
nexilin
241
0.89
chr16_87554734_87554885 1.32 Map3k7cl
Map3k7 C-terminal like
1479
0.33
chr19_44837256_44838138 1.31 1700039E22Rik
RIKEN cDNA 1700039E22 gene
1759
0.28
chr6_99203165_99203959 1.31 Foxp1
forkhead box P1
40544
0.2
chr3_84925424_84926533 1.30 Fbxw7
F-box and WD-40 domain protein 7
498
0.86
chr9_77637824_77638260 1.30 Klhl31
kelch-like 31
1542
0.38
chr16_44015370_44016774 1.30 Gramd1c
GRAM domain containing 1C
364
0.83
chr14_101841178_101841822 1.30 Lmo7
LIM domain only 7
681
0.79
chr15_58323594_58324160 1.30 Klhl38
kelch-like 38
292
0.91
chr11_77350862_77351013 1.29 Ssh2
slingshot protein phosphatase 2
2649
0.28
chr13_46422196_46422985 1.29 Rbm24
RNA binding motif protein 24
768
0.72
chr3_121955508_121955659 1.29 Arhgap29
Rho GTPase activating protein 29
2353
0.31
chr11_111067503_111068134 1.28 Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
1654
0.5
chr13_71960720_71961584 1.28 Irx1
Iroquois homeobox 1
436
0.87
chr8_104608784_104609059 1.28 Cdh16
cadherin 16
4343
0.11
chr16_72444168_72445169 1.28 Gm49670
predicted gene, 49670
72227
0.13
chr4_94741041_94742202 1.28 Tek
TEK receptor tyrosine kinase
2103
0.34
chr2_75149459_75150258 1.27 2600014E21Rik
RIKEN cDNA 2600014E21 gene
10978
0.15
chr2_19661271_19661512 1.27 Otud1
OTU domain containing 1
3639
0.16
chr4_102257323_102258061 1.27 Pde4b
phosphodiesterase 4B, cAMP specific
2462
0.42
chr12_9573836_9576858 1.27 Osr1
odd-skipped related transcription factor 1
906
0.56
chr2_115858978_115861125 1.27 Meis2
Meis homeobox 2
8816
0.31
chr18_54452409_54453689 1.27 Gm50361
predicted gene, 50361
23716
0.19
chr1_62795476_62796303 1.26 Gm37121
predicted gene, 37121
13413
0.19
chr11_101791673_101791824 1.26 Etv4
ets variant 4
6377
0.16
chr10_14542031_14542623 1.26 Gm46212
predicted gene, 46212
2163
0.25
chr7_67421454_67422158 1.26 Gm33926
predicted gene, 33926
22127
0.17
chr3_123324647_123325145 1.25 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
9930
0.18
chr4_123787646_123788940 1.25 Rhbdl2
rhomboid like 2
418
0.8
chr3_79884429_79885439 1.25 Gask1b
golgi associated kinase 1B
3
0.97
chr4_152316569_152316720 1.25 Rnf207
ring finger protein 207
316
0.82
chrX_168778779_168779062 1.25 Gm15233
predicted gene 15233
3664
0.28
chr14_89826815_89826966 1.25 Gm10110
predicted gene 10110
71576
0.13
chr17_30467511_30468177 1.24 Gm9874
predicted gene 9874
16817
0.14
chr6_97457802_97459465 1.24 Frmd4b
FERM domain containing 4B
653
0.74
chr8_102780577_102781067 1.24 Gm45258
predicted gene 45258
220
0.93
chr11_38157027_38157290 1.23 Gm12129
predicted gene 12129
61911
0.15
chr10_53340367_53340889 1.23 Pln
phospholamban
2923
0.17
chr1_153329741_153330128 1.22 Lamc1
laminin, gamma 1
2852
0.24
chr2_34873990_34875403 1.22 Cutal
cutA divalent cation tolerance homolog-like
178
0.6
chr12_37110777_37111603 1.22 Meox2
mesenchyme homeobox 2
2650
0.27
chr8_57335453_57336294 1.22 Gm34030
predicted gene, 34030
1288
0.34
chr2_163392737_163392895 1.22 Jph2
junctophilin 2
5133
0.15
chr16_92632222_92632736 1.22 Gm26626
predicted gene, 26626
19665
0.2
chr12_9570099_9571217 1.22 1700022H16Rik
RIKEN cDNA 1700022H16 gene
73
0.9
chr15_92520747_92521652 1.21 Pdzrn4
PDZ domain containing RING finger 4
34538
0.23
chr18_15280955_15281588 1.21 E430002N23Rik
RIKEN cDNA E430002N23 gene
31428
0.17
chr3_121969276_121969790 1.21 Arhgap29
Rho GTPase activating protein 29
1704
0.38
chr17_12766020_12767485 1.21 Igf2r
insulin-like growth factor 2 receptor
2912
0.17
chr9_100506428_100506720 1.20 Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
282
0.88
chr6_48705812_48706743 1.20 Gimap6
GTPase, IMAP family member 6
41
0.93
chr13_110397628_110399698 1.20 Plk2
polo like kinase 2
866
0.68

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Foxf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
1.4 7.0 GO:0003175 tricuspid valve development(GO:0003175)
1.3 4.0 GO:0007525 somatic muscle development(GO:0007525)
1.3 3.8 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.1 2.1 GO:0003166 bundle of His development(GO:0003166)
0.9 3.5 GO:0035995 detection of muscle stretch(GO:0035995)
0.8 3.3 GO:0060486 Clara cell differentiation(GO:0060486)
0.8 2.3 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.8 2.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.7 1.4 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.7 1.4 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.7 0.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 5.6 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.7 2.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.7 2.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.7 2.0 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.7 1.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.7 2.0 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.6 1.2 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.6 3.0 GO:0007494 midgut development(GO:0007494)
0.6 0.6 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.6 1.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 2.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 2.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.5 3.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.5 2.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 1.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 1.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.5 1.5 GO:0060618 nipple development(GO:0060618)
0.5 1.0 GO:0098911 regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.5 2.0 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.5 2.3 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.5 1.4 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.5 0.9 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.5 0.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.5 0.5 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.5 1.4 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.4 2.6 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.4 2.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.4 1.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.4 0.4 GO:0098901 regulation of cardiac muscle cell action potential(GO:0098901)
0.4 2.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 0.8 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.4 1.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.4 0.8 GO:0060931 sinoatrial node cell development(GO:0060931)
0.4 1.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.4 1.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.4 3.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.4 1.1 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.4 3.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.4 1.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.4 1.1 GO:0060437 lung growth(GO:0060437)
0.4 3.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.3 1.4 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.3 1.0 GO:0001757 somite specification(GO:0001757)
0.3 1.0 GO:1900200 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.3 0.7 GO:0016095 polyprenol catabolic process(GO:0016095)
0.3 1.0 GO:1902744 negative regulation of lamellipodium organization(GO:1902744)
0.3 0.7 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.3 3.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.3 1.3 GO:0032347 regulation of aldosterone biosynthetic process(GO:0032347) regulation of cortisol biosynthetic process(GO:2000064)
0.3 2.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.3 0.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 0.9 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.3 0.6 GO:0071673 regulation of smooth muscle cell chemotaxis(GO:0071671) positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.3 1.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.3 0.9 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.3 0.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.5 GO:1904424 regulation of GTP binding(GO:1904424)
0.3 1.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.3 1.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 0.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 0.9 GO:0061156 pulmonary artery morphogenesis(GO:0061156)
0.3 0.3 GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.3 0.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.3 0.3 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.3 2.5 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.3 1.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.3 1.3 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.3 1.0 GO:0061074 regulation of neural retina development(GO:0061074)
0.3 0.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 1.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.3 0.8 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.3 0.8 GO:0061355 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.3 0.8 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 2.0 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.2 0.5 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.2 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 1.0 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.2 2.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 0.7 GO:1902946 protein localization to early endosome(GO:1902946) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.2 1.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.7 GO:0046208 spermine catabolic process(GO:0046208)
0.2 1.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2 0.7 GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
0.2 0.5 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.2 0.5 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.2 0.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 0.7 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.2 0.7 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 0.4 GO:0010912 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.2 1.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 0.7 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2 0.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 0.2 GO:0060379 cardiac muscle cell myoblast differentiation(GO:0060379)
0.2 0.4 GO:0003163 sinoatrial node development(GO:0003163)
0.2 0.6 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 0.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 1.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 0.6 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.2 0.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 0.6 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.4 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 0.6 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.2 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.8 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.2 0.4 GO:1902996 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.2 1.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 2.6 GO:0014741 negative regulation of muscle hypertrophy(GO:0014741)
0.2 1.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.2 0.6 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 1.0 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000341) positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.2 0.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 2.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.4 GO:0061439 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439)
0.2 1.3 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of heart growth(GO:0061117)
0.2 0.8 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.2 0.2 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 0.8 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.4 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.2 0.7 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.2 1.3 GO:0097264 self proteolysis(GO:0097264)
0.2 0.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 0.4 GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
0.2 0.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.7 GO:0072675 osteoclast fusion(GO:0072675)
0.2 0.5 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.2 0.5 GO:0050904 diapedesis(GO:0050904)
0.2 0.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 0.5 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.7 GO:0071694 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.2 2.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.2 3.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.2 2.6 GO:0030325 adrenal gland development(GO:0030325)
0.2 1.0 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 0.2 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.2 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.5 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 0.3 GO:0018992 germ-line sex determination(GO:0018992)
0.2 0.2 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.2 0.8 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.2 0.3 GO:0055006 cardiac cell development(GO:0055006)
0.2 4.1 GO:0010107 potassium ion import(GO:0010107)
0.2 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.2 GO:0035799 ureter maturation(GO:0035799)
0.2 0.6 GO:0009115 xanthine catabolic process(GO:0009115)
0.2 1.0 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.2 1.8 GO:0060420 regulation of heart growth(GO:0060420)
0.2 1.3 GO:0030953 astral microtubule organization(GO:0030953)
0.2 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.0 GO:1902913 positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.2 0.3 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.2 0.6 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.5 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.2 0.8 GO:0032817 regulation of natural killer cell proliferation(GO:0032817)
0.2 0.8 GO:0032596 protein transport into membrane raft(GO:0032596)
0.2 0.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.2 0.5 GO:0003383 apical constriction(GO:0003383)
0.2 0.9 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 0.5 GO:0006768 biotin metabolic process(GO:0006768)
0.1 0.3 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.6 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.3 GO:0097369 sodium ion import(GO:0097369)
0.1 0.7 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 0.7 GO:0032196 transposition(GO:0032196)
0.1 0.6 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1 1.2 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.1 0.3 GO:0035787 cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.3 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512)
0.1 0.4 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:0046103 inosine biosynthetic process(GO:0046103)
0.1 1.2 GO:0001553 luteinization(GO:0001553)
0.1 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1 1.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 0.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:1903975 regulation of glial cell migration(GO:1903975)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.5 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1 0.4 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.1 1.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0046449 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.2 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 1.2 GO:1990845 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.1 0.6 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 0.3 GO:0045297 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.1 1.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.7 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.1 GO:0002339 B cell selection(GO:0002339)
0.1 0.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.1 GO:1902669 positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.1 0.3 GO:0072093 metanephric renal vesicle formation(GO:0072093)
0.1 0.9 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.1 GO:2000316 regulation of T-helper 17 type immune response(GO:2000316)
0.1 0.1 GO:0060911 cardiac cell fate commitment(GO:0060911)
0.1 1.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 0.5 GO:0099515 actin filament-based transport(GO:0099515)
0.1 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.1 GO:0003174 mitral valve development(GO:0003174)
0.1 0.6 GO:0097531 mast cell migration(GO:0097531)
0.1 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.6 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.1 0.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.4 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.1 1.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.1 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.1 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.4 GO:0015884 folic acid transport(GO:0015884)
0.1 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.2 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.3 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.1 0.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.1 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.2 GO:2001182 regulation of interleukin-12 secretion(GO:2001182)
0.1 0.4 GO:1903887 motile primary cilium assembly(GO:1903887)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.1 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.1 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.1 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.1 GO:0048880 sensory system development(GO:0048880)
0.1 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.3 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.6 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.2 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.1 0.4 GO:0019732 antifungal humoral response(GO:0019732)
0.1 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:1901077 regulation of relaxation of muscle(GO:1901077)
0.1 0.2 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.4 GO:0035826 rubidium ion transport(GO:0035826)
0.1 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.2 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.2 GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis(GO:0072038)
0.1 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.2 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0051775 response to redox state(GO:0051775)
0.1 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0015819 lysine transport(GO:0015819)
0.1 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.5 GO:0002664 regulation of T cell tolerance induction(GO:0002664)
0.1 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.1 GO:0072602 interleukin-4 secretion(GO:0072602)
0.1 0.4 GO:0031000 response to caffeine(GO:0031000)
0.1 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.1 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.6 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 1.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.1 GO:0051451 myoblast migration(GO:0051451)
0.1 0.4 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.1 GO:0061643 chemorepulsion of axon(GO:0061643)
0.1 0.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.3 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:0045909 positive regulation of vasodilation(GO:0045909)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.9 GO:0001945 lymph vessel development(GO:0001945)
0.1 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.1 GO:0086103 G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
0.1 0.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.2 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.6 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 1.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.2 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.1 GO:0014028 notochord formation(GO:0014028)
0.1 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.1 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.1 0.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 1.3 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.1 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.1 GO:2001026 regulation of endothelial cell chemotaxis(GO:2001026)
0.1 0.1 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.1 GO:0035973 aggrephagy(GO:0035973)
0.1 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.2 GO:0019532 oxalate transport(GO:0019532)
0.1 1.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.2 GO:0006573 valine metabolic process(GO:0006573)
0.1 0.2 GO:1904751 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.1 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.1 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239)
0.1 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.1 GO:0033034 positive regulation of myeloid cell apoptotic process(GO:0033034)
0.1 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.1 GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.1 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.7 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin(GO:0003081)
0.1 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.1 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.1 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.1 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.1 GO:0032351 negative regulation of hormone metabolic process(GO:0032351)
0.1 0.9 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.1 1.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.1 GO:0055017 cardiac muscle tissue growth(GO:0055017)
0.1 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.1 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.2 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.1 0.1 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.1 GO:0003348 cardiac endothelial cell differentiation(GO:0003348)
0.1 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.1 GO:0003177 pulmonary valve development(GO:0003177) pulmonary valve morphogenesis(GO:0003184)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.5 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.8 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.0 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.6 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.3 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 0.2 GO:0060600 dichotomous subdivision of an epithelial terminal unit(GO:0060600)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0 0.0 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 1.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.0 0.0 GO:0042504 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.0 0.1 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.0 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.0 0.9 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.6 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0035935 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.1 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.4 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.0 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0060112 generation of ovulation cycle rhythm(GO:0060112)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.1 GO:0051794 regulation of catagen(GO:0051794)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.0 GO:0060973 cell migration involved in heart development(GO:0060973)
0.0 0.1 GO:2001260 regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0 0.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.0 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.5 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.0 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.0 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 1.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.1 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0086001 cardiac muscle cell action potential(GO:0086001)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014)
0.0 0.1 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.3 GO:0002828 regulation of type 2 immune response(GO:0002828)
0.0 0.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.1 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 2.5 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:0070255 regulation of mucus secretion(GO:0070255)
0.0 0.0 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0007530 sex determination(GO:0007530)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.0 GO:2001212 regulation of vasculogenesis(GO:2001212)
0.0 0.0 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.0 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.0 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.1 GO:0042748 circadian sleep/wake cycle, non-REM sleep(GO:0042748)
0.0 0.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.0 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0051284 positive regulation of sequestering of calcium ion(GO:0051284)
0.0 0.1 GO:0044116 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117)
0.0 0.0 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.0 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.0 GO:0002155 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.1 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 0.0 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084)
0.0 0.0 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056)
0.0 0.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.0 GO:0007227 signal transduction downstream of smoothened(GO:0007227)
0.0 0.0 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.0 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0010878 cholesterol storage(GO:0010878)
0.0 0.0 GO:1902302 regulation of potassium ion export(GO:1902302)
0.0 0.1 GO:0032095 regulation of response to food(GO:0032095)
0.0 0.2 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0060914 heart formation(GO:0060914)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.1 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.0 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.0 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.0 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.0 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143)
0.0 0.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.0 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.0 0.1 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)
0.0 0.0 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.0 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.0 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.1 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.0 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.0 GO:0002645 positive regulation of tolerance induction(GO:0002645)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 0.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.0 GO:0051956 negative regulation of amino acid transport(GO:0051956)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.0 GO:0032660 regulation of interleukin-17 production(GO:0032660) positive regulation of interleukin-17 production(GO:0032740)
0.0 0.0 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:0046950 cellular ketone body metabolic process(GO:0046950) ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0021855 hypothalamus cell migration(GO:0021855)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.0 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.1 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.0 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.0 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0044243 multicellular organism catabolic process(GO:0044243)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.0 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0 0.1 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 5.1 GO:0005861 troponin complex(GO:0005861)
0.4 1.3 GO:0048179 activin receptor complex(GO:0048179)
0.4 1.8 GO:0044316 cone cell pedicle(GO:0044316)
0.4 1.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.4 5.0 GO:0005916 fascia adherens(GO:0005916)
0.4 1.5 GO:1990696 USH2 complex(GO:1990696)
0.4 2.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 5.7 GO:0031430 M band(GO:0031430)
0.3 1.0 GO:0005606 laminin-1 complex(GO:0005606)
0.3 0.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.1 GO:0030478 actin cap(GO:0030478)
0.3 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 20.9 GO:0030018 Z disc(GO:0030018)
0.2 0.7 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.2 4.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.2 1.2 GO:0005915 zonula adherens(GO:0005915)
0.2 2.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 0.8 GO:0071953 elastic fiber(GO:0071953)
0.2 1.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.2 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 2.4 GO:0031674 I band(GO:0031674)
0.2 1.6 GO:0016460 myosin II complex(GO:0016460)
0.2 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.9 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 2.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.8 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0000802 transverse filament(GO:0000802)
0.1 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 2.3 GO:0097440 apical dendrite(GO:0097440)
0.1 0.4 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.3 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.2 GO:0005605 basal lamina(GO:0005605)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 7.9 GO:0005604 basement membrane(GO:0005604)
0.1 4.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 3.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.8 GO:0001527 microfibril(GO:0001527)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.2 GO:0000322 storage vacuole(GO:0000322)
0.1 6.5 GO:0042383 sarcolemma(GO:0042383)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:1990357 terminal web(GO:1990357)
0.1 0.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.2 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.1 GO:0043511 inhibin complex(GO:0043511)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.1 GO:0042611 MHC protein complex(GO:0042611)
0.1 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0009279 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0005767 secondary lysosome(GO:0005767)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 3.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.0 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 1.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 5.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:1904949 ATPase complex(GO:1904949)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.7 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 1.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 1.5 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0070538 oleic acid binding(GO:0070538)
1.1 4.4 GO:0031433 telethonin binding(GO:0031433)
1.0 2.9 GO:0030172 troponin C binding(GO:0030172)
0.8 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 2.7 GO:0051525 NFAT protein binding(GO:0051525)
0.5 2.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 1.6 GO:0004948 calcitonin receptor activity(GO:0004948)
0.5 1.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.5 1.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 2.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 1.3 GO:0031013 troponin I binding(GO:0031013)
0.4 1.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 1.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 1.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3 1.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 1.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 1.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 0.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 4.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 1.8 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.3 2.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.3 0.9 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.3 1.1 GO:0019808 polyamine binding(GO:0019808)
0.3 0.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 2.5 GO:0031432 titin binding(GO:0031432)
0.3 3.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 1.6 GO:0034805 enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.3 1.1 GO:0009374 biotin binding(GO:0009374)
0.3 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 1.6 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 0.8 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.7 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 0.7 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.2 1.0 GO:0030984 kininogen binding(GO:0030984)
0.2 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 0.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.9 GO:0042731 PH domain binding(GO:0042731)
0.2 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 4.6 GO:0030552 cAMP binding(GO:0030552)
0.2 1.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 2.1 GO:0070700 BMP receptor binding(GO:0070700)
0.2 3.3 GO:0008143 poly(A) binding(GO:0008143)
0.2 0.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.2 2.2 GO:0031005 filamin binding(GO:0031005)
0.2 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.0 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.2 1.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 1.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 0.6 GO:0070052 collagen V binding(GO:0070052)
0.2 1.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.3 GO:0008688 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.2 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.2 2.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.2 1.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.9 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.7 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.2 GO:0017166 vinculin binding(GO:0017166)
0.2 0.7 GO:0038064 collagen receptor activity(GO:0038064)
0.2 0.5 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 14.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 1.9 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 2.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.3 GO:0043199 sulfate binding(GO:0043199)
0.1 1.4 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.5 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.7 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.1 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.3 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 6.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.5 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.3 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.1 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1 8.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 2.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.2 GO:0036122 BMP binding(GO:0036122)
0.1 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.4 GO:0051400 BH domain binding(GO:0051400)
0.1 1.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0030553 cGMP binding(GO:0030553)
0.1 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.0 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 4.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.4 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.3 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 1.0 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 1.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 1.8 GO:0060090 binding, bridging(GO:0060090)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0019002 GMP binding(GO:0019002)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0034549 N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0019976 interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.3 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.0 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 4.7 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.0 GO:0016615 malate dehydrogenase activity(GO:0016615)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 2.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 2.1 PID ALK2 PATHWAY ALK2 signaling events
0.2 2.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 1.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 3.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 5.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 4.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.1 ST ADRENERGIC Adrenergic Pathway
0.1 3.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 5.0 PID FGF PATHWAY FGF signaling pathway
0.1 3.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.6 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 9.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.3 PID BMP PATHWAY BMP receptor signaling
0.1 8.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.8 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 3.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.2 3.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 0.8 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.2 3.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 0.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 2.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.2 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 0.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 4.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.6 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 1.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.1 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.2 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.1 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 6.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 3.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.1 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines