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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Foxg1

Z-value: 0.67

Motif logo

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Transcription factors associated with Foxg1

Gene Symbol Gene ID Gene Info
Foxg1
ENSMUSG00000020950.9 forkhead box G1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_49382714_49384085Foxg13920.722333-0.028.9e-01Click!

Activity of the Foxg1 motif across conditions

Conditions sorted by the z-value of the Foxg1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_57784547_57786586 2.14 Fabp7
 fatty acid binding protein 7, brain
 643
 0.68
chr16_18429039_18430122 1.61 Txnrd2
 thioredoxin reductase 2
 655
 0.54
chr8_80494890_80495139 1.35 Gypa
 glycophorin A
 1233
 0.53
chr7_78914724_78915335 1.33 Isg20
 interferon-stimulated protein
 700
 0.57
chr8_80497324_80498362 1.31 Gypa
 glycophorin A
 4062
 0.27
chr6_118757029_118757180 1.29 Cacna1c
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 870
 0.71
chr7_62422629_62423664 1.25 Gm32061
 predicted gene, 32061
 99
 0.96
chr1_168287219_168287370 1.04 Gm37524
 predicted gene, 37524
 50377
 0.16
chr11_102364387_102365146 1.03 Slc4a1
 solute carrier family 4 (anion exchanger), member 1
 481
 0.67
chr11_54026747_54027441 0.96 Slc22a4
 solute carrier family 22 (organic cation transporter), member 4
 858
 0.54
chr2_105680581_105683424 0.94 Pax6
 paired box 6
 290
 0.89
chr7_143004834_143005031 0.87 Tspan32
 tetraspanin 32
 114
 0.94
chr8_80868370_80868642 0.87 Gm31105
 predicted gene, 31105
 11434
 0.18
chr13_41236642_41237224 0.84 Gm32063
 predicted gene, 32063
 588
 0.6
chr7_90083908_90084239 0.79 Gm5341
 predicted pseudogene 5341
 23895
 0.11
chr6_87776091_87777171 0.78 Gm43904
 predicted gene, 43904
 488
 0.55
chr9_91378153_91379783 0.76 Zic4
 zinc finger protein of the cerebellum 4
 326
 0.81
chr6_128526086_128526400 0.72 Pzp
 PZP, alpha-2-macroglobulin like
 460
 0.65
chr17_24202438_24203465 0.71 Tbc1d24
 TBC1 domain family, member 24
 2531
 0.12
chr6_52162888_52164000 0.70 Hoxa2
 homeobox A2
 1387
 0.15
chr2_74713881_74716227 0.69 Hoxd3os1
 homeobox D3, opposite strand 1
 942
 0.23
chr10_12962620_12962953 0.68 Stx11
 syntaxin 11
 1472
 0.41
chr10_91967800_91968283 0.67 Gm31592
 predicted gene, 31592
 79212
 0.1
chr11_74572004_74572226 0.66 Rap1gap2
 RAP1 GTPase activating protein 2
 18009
 0.18
chr12_116407284_116407647 0.66 Ncapg2
 non-SMC condensin II complex, subunit G2
 2031
 0.24
chr9_70934045_70934653 0.65 Lipc
 lipase, hepatic
 264
 0.92
chr4_119183706_119183857 0.65 Ermap
 erythroblast membrane-associated protein
 4966
 0.1
chr17_71525336_71525487 0.64 Ndc80
 NDC80 kinetochore complex component
 1379
 0.24
chr4_141076285_141076997 0.64 Necap2
 NECAP endocytosis associated 2
 1584
 0.24
chr13_47104855_47106138 0.63 Dek
 DEK oncogene (DNA binding)
 334
 0.73
chr4_143045346_143045497 0.62 6330411D24Rik
 RIKEN cDNA 6330411D24 gene
 28345
 0.19
chr10_80570596_80572042 0.61 Klf16
 Kruppel-like factor 16
 6002
 0.08
chr5_116021804_116022431 0.61 Prkab1
 protein kinase, AMP-activated, beta 1 non-catalytic subunit
 471
 0.73
chr14_109511936_109512087 0.60 Gm18977
 predicted gene, 18977
 11088
 0.28
chr18_63727695_63728070 0.59 Wdr7
 WD repeat domain 7
 11182
 0.16
chr3_85991395_85991798 0.59 Prss48
 protease, serine 48
 10895
 0.12
chr11_97471430_97471581 0.58 Arhgap23
 Rho GTPase activating protein 23
 19375
 0.13
chr9_107301461_107301858 0.58 Gm17041
 predicted gene 17041
 179
 0.88
chr2_26349516_26349790 0.57 Dnlz
 DNL-type zinc finger
 2447
 0.12
chr4_129463918_129464422 0.57 Bsdc1
 BSD domain containing 1
 372
 0.74
chr15_77756117_77756516 0.56 Apol8
 apolipoprotein L 8
 666
 0.54
chr12_24645782_24646298 0.55 Klf11
 Kruppel-like factor 11
 5234
 0.16
chr10_80569864_80570541 0.55 Klf16
 Kruppel-like factor 16
 7119
 0.08
chr6_54851742_54852146 0.54 Znrf2
 zinc and ring finger 2
 34496
 0.15
chr16_20713558_20714737 0.54 Clcn2
 chloride channel, voltage-sensitive 2
 479
 0.59
chr19_36896833_36896984 0.53 Tnks2
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
 16335
 0.17
chr4_119189472_119189950 0.53 Ermap
 erythroblast membrane-associated protein
 240
 0.84
chr5_116573497_116573648 0.53 Gm42854
 predicted gene 42854
 77
 0.97
chr7_45238275_45239242 0.53 Cd37
 CD37 antigen
 38
 0.92
chr7_99803412_99803631 0.53 F730035P03Rik
 RIKEN cDNA F730035P03 gene
 21982
 0.1
chr9_43746633_43747189 0.52 Gm30015
 predicted gene, 30015
 811
 0.54
chr11_27966865_27967016 0.52 Gm12080
 predicted gene 12080
 79095
 0.11
chr4_130006445_130007362 0.51 Adgrb2
 adhesion G protein-coupled receptor B2
 2973
 0.19
chr12_69783268_69783598 0.51 4930512B01Rik
 RIKEN cDNA 4930512B01 gene
 6855
 0.13
chr14_25536740_25537143 0.51 Mir3075
 microRNA 3075
 2502
 0.26
chr16_8687825_8687976 0.51 Gm5767
 predicted gene 5767
 5070
 0.14
chr14_69282071_69282727 0.51 Gm20236
 predicted gene, 20236
 259
 0.8
chr14_69500320_69500976 0.50 Gm37094
 predicted gene, 37094
 258
 0.81
chr5_74064229_74066220 0.50 Usp46
 ubiquitin specific peptidase 46
 524
 0.65
chr15_73182349_73182927 0.49 Ago2
 argonaute RISC catalytic subunit 2
 2297
 0.3
chr12_118650955_118651106 0.49 Gm9267
 predicted gene 9267
 48353
 0.15
chr11_4487067_4487818 0.49 Mtmr3
 myotubularin related protein 3
 924
 0.59
chr3_95517184_95517335 0.48 Ctss
 cathepsin S
 9527
 0.1
chr14_118229781_118230155 0.48 Gm4675
 predicted gene 4675
 6264
 0.13
chr10_19483385_19484135 0.48 Gm33104
 predicted gene, 33104
 2955
 0.29
chr11_69399334_69402458 0.48 Kdm6bos
 KDM1 lysine (K)-specific demethylase 6B, opposite strand
 617
 0.47
chr6_89355649_89355800 0.47 Plxna1
 plexin A1
 1993
 0.29
chr10_78427526_78427677 0.47 4921516A02Rik
 RIKEN cDNA 4921516A02 gene
 670
 0.41
chr10_81153659_81153953 0.46 Pias4
 protein inhibitor of activated STAT 4
 2318
 0.11
chr17_15501788_15502060 0.46 Tbp
 TATA box binding protein
 1065
 0.34
chr3_154092419_154093223 0.46 Gm3076
 predicted gene 3076
 39519
 0.13
chr5_137290070_137291279 0.46 Ache
 acetylcholinesterase
 1427
 0.17
chr16_8670580_8670942 0.45 Carhsp1
 calcium regulated heat stable protein 1
 1394
 0.29
chr13_75715151_75715379 0.45 Ell2
 elongation factor RNA polymerase II 2
 7554
 0.13
chr13_23417840_23417991 0.45 Abt1
 activator of basal transcription 1
 5951
 0.09
chr18_54422355_54422833 0.44 Redrum
 Redrum, erythroid developmental long intergenic non-protein coding transcript
 299
 0.93
chr13_100676259_100676561 0.44 Ccdc125
 coiled-coil domain containing 125
 6637
 0.12
chr14_115046048_115046375 0.44 Mir92-1
 microRNA 92-1
 1784
 0.14
chr5_139391800_139391951 0.43 Gpr146
 G protein-coupled receptor 146
 2090
 0.2
chr11_94264019_94264170 0.43 Gm21885
 predicted gene, 21885
 17779
 0.14
chr15_103250315_103251530 0.43 Nfe2
 nuclear factor, erythroid derived 2
 543
 0.62
chr7_62414907_62415687 0.42 Mkrn3
 makorin, ring finger protein, 3
 4842
 0.18
chr1_90947541_90947692 0.42 Prlh
 prolactin releasing hormone
 5492
 0.15
chr10_127323007_127323393 0.42 Arhgap9
 Rho GTPase activating protein 9
 507
 0.55
chr11_4488078_4488309 0.42 Mtmr3
 myotubularin related protein 3
 173
 0.95
chr2_116056837_116059755 0.41 Meis2
 Meis homeobox 2
 546
 0.75
chr7_16103274_16103425 0.41 Napa
 N-ethylmaleimide sensitive fusion protein attachment protein alpha
 4267
 0.14
chr11_116647941_116648526 0.41 Prcd
 photoreceptor disc component
 5301
 0.09
chr1_9780296_9780452 0.41 1700034P13Rik
 RIKEN cDNA 1700034P13 gene
 3404
 0.17
chr16_91222072_91224159 0.41 Gm49614
 predicted gene, 49614
 189
 0.9
chr4_108060098_108060443 0.40 Scp2
 sterol carrier protein 2, liver
 11093
 0.13
chrX_42155222_42155373 0.40 Stag2
 stromal antigen 2
 3117
 0.24
chr10_57499477_57499901 0.40 Hsf2
 heat shock factor 2
 685
 0.68
chr5_137382579_137382730 0.40 Zan
 zonadhesin
 19084
 0.09
chr6_90333325_90334527 0.40 Uroc1
 urocanase domain containing 1
 637
 0.57
chr17_34950362_34951201 0.40 Snord52
 small nucleolar RNA, C/D box 52
 236
 0.58
chr4_154966258_154966899 0.39 Pank4
 pantothenate kinase 4
 2445
 0.18
chr16_8612946_8613812 0.39 Abat
 4-aminobutyrate aminotransferase
 501
 0.67
chr3_89209863_89210054 0.39 Mtx1
 metaxin 1
 136
 0.74
chr11_48803049_48803584 0.39 Rack1
 receptor for activated C kinase 1
 164
 0.48
chr6_88501831_88502191 0.39 Gm44170
 predicted gene, 44170
 1594
 0.29
chr8_71377836_71378740 0.39 Nr2f6
 nuclear receptor subfamily 2, group F, member 6
 2498
 0.14
chr12_103735553_103735704 0.39 Serpina1b
 serine (or cysteine) preptidase inhibitor, clade A, member 1B
 2530
 0.16
chr6_41702817_41703169 0.39 Kel
 Kell blood group
 1346
 0.32
chr18_14459496_14459647 0.39 Gm50098
 predicted gene, 50098
 32434
 0.17
chr1_67125661_67125812 0.39 Cps1
 carbamoyl-phosphate synthetase 1
 2710
 0.34
chr7_127661632_127661895 0.38 Gm44760
 predicted gene 44760
 3529
 0.11
chr13_73483496_73483773 0.38 Lpcat1
 lysophosphatidylcholine acyltransferase 1
 11883
 0.21
chr2_152785455_152786223 0.38 Gm23802
 predicted gene, 23802
 12950
 0.11
chr7_19691393_19692666 0.38 Apoc1
 apolipoprotein C-I
 462
 0.59
chr1_136960004_136960405 0.38 Nr5a2
 nuclear receptor subfamily 5, group A, member 2
 176
 0.96
chr19_14889594_14889745 0.38 Gm5513
 predicted pseudogene 5513
 71097
 0.13
chr11_96202439_96204563 0.38 Hoxb13
 homeobox B13
 9185
 0.1
chrX_150554562_150554911 0.37 Alas2
 aminolevulinic acid synthase 2, erythroid
 699
 0.62
chrX_96241467_96241787 0.37 Mir223
 microRNA 223
 1190
 0.35
chr15_12203564_12203715 0.37 Mtmr12
 myotubularin related protein 12
 1389
 0.28
chr5_35609246_35609861 0.37 Acox3
 acyl-Coenzyme A oxidase 3, pristanoyl
 546
 0.71
chr9_79823449_79823600 0.36 Filip1
 filamin A interacting protein 1
 7474
 0.15
chr1_168381191_168381418 0.36 Gm38381
 predicted gene, 38381
 30496
 0.18
chr13_59668566_59668950 0.36 Golm1
 golgi membrane protein 1
 7014
 0.1
chr14_98164357_98165375 0.36 Dach1
 dachshund family transcription factor 1
 4677
 0.28
chr9_70502649_70503336 0.36 Rnf111
 ring finger 111
 362
 0.81
chr4_154960570_154962200 0.36 Gm20421
 predicted gene 20421
 293
 0.57
chr12_29529828_29531185 0.36 Gm20208
 predicted gene, 20208
 609
 0.74
chr1_121177384_121178460 0.36 Gm29359
 predicted gene 29359
 46354
 0.15
chr11_58868459_58868610 0.35 2810021J22Rik
 RIKEN cDNA 2810021J22 gene
 1267
 0.21
chr8_70656342_70656817 0.35 Pgpep1
 pyroglutamyl-peptidase I
 859
 0.37
chr2_84735706_84738103 0.35 Ypel4
 yippee like 4
 2677
 0.11
chr14_61650328_61650516 0.35 Gm27017
 predicted gene, 27017
 1472
 0.19
chr16_17949655_17949806 0.35 Slc25a1
 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
 21511
 0.09
chr8_61515132_61515409 0.35 Palld
 palladin, cytoskeletal associated protein
 630
 0.77
chr15_96292843_96292994 0.34 Arid2
 AT rich interactive domain 2 (ARID, RFX-like)
 5345
 0.21
chr11_3488055_3488462 0.34 Pla2g3
 phospholipase A2, group III
 26
 0.95
chr1_71100990_71101619 0.34 Bard1
 BRCA1 associated RING domain 1
 1842
 0.43
chr15_76179745_76180476 0.34 Plec
 plectin
 7933
 0.09
chr11_60538080_60539333 0.34 Alkbh5
 alkB homolog 5, RNA demethylase
 728
 0.48
chr8_47531539_47531690 0.34 Trappc11
 trafficking protein particle complex 11
 1853
 0.25
chr4_130108875_130109149 0.34 Pef1
 penta-EF hand domain containing 1
 1456
 0.34
chr5_64588253_64588408 0.34 Gm3716
 predicted gene 3716
 14830
 0.11
chr9_114562215_114562607 0.34 Trim71
 tripartite motif-containing 71
 1958
 0.3
chr2_33867715_33867866 0.34 Mvb12b
 multivesicular body subunit 12B
 19055
 0.2
chr3_108573576_108574011 0.33 Taf13
 TATA-box binding protein associated factor 13
 2082
 0.15
chr13_97778790_97779019 0.33 Gm47577
 predicted gene, 47577
 11660
 0.15
chr9_110653127_110654518 0.33 Nbeal2
 neurobeachin-like 2
 320
 0.77
chr13_83741336_83742027 0.33 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 2818
 0.16
chr10_80834399_80836114 0.33 Mir1982
 microRNA 1982
 6459
 0.07
chr10_43580494_43581222 0.33 Cd24a
 CD24a antigen
 923
 0.48
chr11_55449682_55449833 0.33 Atox1
 antioxidant 1 copper chaperone
 11440
 0.11
chr1_75235806_75235957 0.33 Dnajb2
 DnaJ heat shock protein family (Hsp40) member B2
 525
 0.5
chr18_54436033_54436373 0.32 Redrum
 Redrum, erythroid developmental long intergenic non-protein coding transcript
 13908
 0.23
chr5_34369874_34370083 0.32 Fam193a
 family with sequence homology 193, member A
 45
 0.97
chr17_26974792_26975099 0.32 Zbtb9
 zinc finger and BTB domain containing 9
 1728
 0.14
chr1_130732649_130733832 0.32 AA986860
 expressed sequence AA986860
 1130
 0.29
chr16_8687033_8687675 0.32 Gm5767
 predicted gene 5767
 4524
 0.14
chr10_81349455_81350420 0.32 Hmg20b
 high mobility group 20B
 254
 0.74
chr13_59763390_59763779 0.32 Isca1
 iron-sulfur cluster assembly 1
 17
 0.94
chr1_23282787_23283466 0.31 Gm27028
 predicted gene, 27028
 8411
 0.12
chr19_53332272_53332423 0.31 Mxi1
 MAX interactor 1, dimerization protein
 1939
 0.25
chr2_105908509_105908660 0.31 Immp1l
 IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
 3946
 0.21
chr9_59660933_59662180 0.31 Pkm
 pyruvate kinase, muscle
 3246
 0.17
chr4_100995628_100995943 0.31 Cachd1
 cache domain containing 1
 1075
 0.53
chrX_153501207_153502250 0.31 Ubqln2
 ubiquilin 2
 3501
 0.22
chr5_112001842_112002220 0.31 Gm42488
 predicted gene 42488
 57796
 0.13
chr11_95013727_95013935 0.30 Samd14
 sterile alpha motif domain containing 14
 3550
 0.13
chr5_104043873_104044030 0.30 Nudt9
 nudix (nucleoside diphosphate linked moiety X)-type motif 9
 2355
 0.16
chr1_177150233_177151142 0.30 Gm38146
 predicted gene, 38146
 15234
 0.16
chr5_142589584_142589802 0.30 Mmd2
 monocyte to macrophage differentiation-associated 2
 6825
 0.15
chr9_107723003_107723309 0.30 Sema3f
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
 12681
 0.09
chr1_139375797_139376462 0.30 Crb1
 crumbs family member 1, photoreceptor morphogenesis associated
 912
 0.52
chr3_84219260_84219630 0.30 Trim2
 tripartite motif-containing 2
 1400
 0.49
chr3_27146047_27146198 0.30 Ect2
 ect2 oncogene
 1079
 0.48
chr2_147180654_147181518 0.30 Nkx2-2os
 NK2 homeobox 2, opposite strand
 2997
 0.2
chr3_105054815_105055585 0.29 Cttnbp2nl
 CTTNBP2 N-terminal like
 2054
 0.3
chr11_57791079_57791485 0.29 2010001A14Rik
 RIKEN cDNA 2010001A14 gene
 10116
 0.14
chr16_30129996_30130199 0.29 Gm6029
 predicted gene 6029
 9362
 0.15
chr10_50891809_50893729 0.29 Sim1
 single-minded family bHLH transcription factor 1
 1985
 0.43
chrX_12067726_12070081 0.29 Bcor
 BCL6 interacting corepressor
 11650
 0.26
chr7_100492685_100494805 0.29 Ucp2
 uncoupling protein 2 (mitochondrial, proton carrier)
 50
 0.95
chr4_132274460_132275262 0.29 Taf12
 TATA-box binding protein associated factor 12
 445
 0.57
chr4_140704067_140704218 0.29 Rcc2
 regulator of chromosome condensation 2
 2669
 0.17
chr8_26384770_26384921 0.29 Gm31898
 predicted gene, 31898
 50868
 0.1
chr16_96441846_96442164 0.29 Itgb2l
 integrin beta 2-like
 1607
 0.32
chr11_102023682_102023894 0.29 Mpp3
 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
 2069
 0.17
chr1_161734865_161735433 0.28 Gm15429
 predicted pseudogene 15429
 7660
 0.15
chr8_92364963_92367136 0.28 Irx5
 Iroquois homeobox 5
 8300
 0.18
chr14_34373709_34374792 0.28 Sncg
 synuclein, gamma
 539
 0.58
chr15_76666348_76670076 0.28 Foxh1
 forkhead box H1
 1590
 0.15
chr5_117122436_117122623 0.28 Taok3
 TAO kinase 3
 2400
 0.21
chr6_31124166_31124436 0.28 5330406M23Rik
 RIKEN cDNA 5330406M23 gene
 13381
 0.11
chr1_13574325_13574563 0.28 Tram1
 translocating chain-associating membrane protein 1
 5354
 0.24
chr6_122609501_122610041 0.28 Gdf3
 growth differentiation factor 3
 53
 0.95
chr11_106312219_106312370 0.28 Cd79b
 CD79B antigen
 2235
 0.17
chr11_100627464_100627615 0.28 Nkiras2
 NFKB inhibitor interacting Ras-like protein 2
 4528
 0.11
chr12_91747422_91747591 0.27 Ston2
 stonin 2
 1422
 0.4
chr11_45855533_45856802 0.27 Clint1
 clathrin interactor 1
 4203
 0.18
chr19_55285309_55285619 0.27 Acsl5
 acyl-CoA synthetase long-chain family member 5
 1130
 0.48
chr14_30942231_30942467 0.27 Itih1
 inter-alpha trypsin inhibitor, heavy chain 1
 928
 0.4
chr15_98843609_98844032 0.27 Kmt2d
 lysine (K)-specific methyltransferase 2D
 5417
 0.09
chr3_68695313_68695505 0.27 Il12a
 interleukin 12a
 1388
 0.42
chr4_53633406_53634189 0.27 Fsd1l
 fibronectin type III and SPRY domain containing 1-like
 2081
 0.3

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxg1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.3 0.9 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.2 0.8 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.2 1.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 0.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.6 GO:0015879 carnitine transport(GO:0015879)
0.1 0.6 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.1 1.6 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.2 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.3 GO:2000981 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.2 GO:0001555 oocyte growth(GO:0001555)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.2 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.1 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.3 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.0 GO:0010535 positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0 0.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 1.1 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.7 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0071864 positive regulation of cell proliferation in bone marrow(GO:0071864)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.4 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.1 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.0 GO:1901873 regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.0 0.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.0 GO:0060847 endothelial cell fate specification(GO:0060847)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0070922 small RNA loading onto RISC(GO:0070922)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.1 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.0 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.0 GO:0000087 mitotic M phase(GO:0000087)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:1904220 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.0 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.0 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.0 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.0 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.0 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.0 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.0 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0 0.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0051938 L-glutamate import(GO:0051938)
0.0 0.0 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0097503 sialylation(GO:0097503)
0.0 0.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.1 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.0 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0043293 apoptosome(GO:0043293)
0.1 0.2 GO:0000125 PCAF complex(GO:0000125)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.8 GO:0008305 integrin complex(GO:0008305)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.0 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 0.8 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 0.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.6 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.8 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 1.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0018593 mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.0 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.0 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.1 GO:0008932 lytic endotransglycosylase activity(GO:0008932)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation