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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Foxn1

Z-value: 0.43

Motif logo

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Transcription factors associated with Foxn1

Gene Symbol Gene ID Gene Info
Foxn1
ENSMUSG00000002057.4 forkhead box N1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_78384887_78385288Foxn114710.236917-0.229.8e-02Click!
chr11_78386075_78386548Foxn12470.847600-0.201.2e-01Click!
chr11_78383526_78383677Foxn129570.133104-0.152.5e-01Click!
chr11_78378001_78378152Foxn184820.094759-0.085.3e-01Click!
chr11_78385731_78386019Foxn16830.508496-0.066.2e-01Click!

Activity of the Foxn1 motif across conditions

Conditions sorted by the z-value of the Foxn1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_83721518_83722206 0.52 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 481
 0.73
chrX_23285148_23285871 0.43 Klhl13
 kelch-like 13
 50
 0.99
chr10_34301557_34301950 0.42 Tspyl4
 TSPY-like 4
 2497
 0.16
chr9_96758931_96759244 0.41 Zbtb38
 zinc finger and BTB domain containing 38
 6256
 0.16
chr5_22746211_22746970 0.38 A930003O13Rik
 RIKEN cDNA A930003O13 gene
 297
 0.65
chr9_113708285_113708476 0.38 Pdcd6ip
 programmed cell death 6 interacting protein
 121
 0.97
chr2_20966052_20966447 0.35 Arhgap21
 Rho GTPase activating protein 21
 1471
 0.39
chr13_13785297_13785737 0.35 Gng4
 guanine nucleotide binding protein (G protein), gamma 4
 1188
 0.47
chr8_123333278_123333633 0.33 Spire2
 spire type actin nucleation factor 2
 742
 0.47
chr2_126675916_126676238 0.32 Gm27003
 predicted gene, 27003
 161
 0.62
chr14_70577418_70577686 0.32 Nudt18
 nudix (nucleoside diphosphate linked moiety X)-type motif 18
 85
 0.95
chr7_36705087_36705327 0.31 Gm37452
 predicted gene, 37452
 4967
 0.15
chr10_40257841_40258099 0.31 Gtf3c6
 general transcription factor IIIC, polypeptide 6, alpha
 138
 0.81
chr19_27217816_27218252 0.31 Vldlr
 very low density lipoprotein receptor
 576
 0.77
chr6_105676979_105678296 0.29 Cntn4
 contactin 4
 23
 0.52
chr9_62040106_62040360 0.29 Paqr5
 progestin and adipoQ receptor family member V
 13377
 0.2
chr6_121183940_121184503 0.29 Pex26
 peroxisomal biogenesis factor 26
 323
 0.84
chr1_188003839_188004226 0.28 9330162B11Rik
 RIKEN cDNA 9330162B11 gene
 4958
 0.26
chr8_104629629_104629943 0.27 Gm33023
 predicted gene, 33023
 1046
 0.27
chr18_11657869_11658260 0.27 Rbbp8
 retinoblastoma binding protein 8, endonuclease
 222
 0.57
chr8_87539918_87540560 0.27 4933402J07Rik
 RIKEN cDNA 4933402J07 gene
 23614
 0.14
chr14_55055435_55055869 0.26 Gm20687
 predicted gene 20687
 159
 0.87
chr17_34295833_34296830 0.26 H2-Aa
 histocompatibility 2, class II antigen A, alpha
 8508
 0.08
chr12_5373600_5373751 0.26 Klhl29
 kelch-like 29
 2007
 0.33
chr17_55447566_55447717 0.25 St6gal2
 beta galactoside alpha 2,6 sialyltransferase 2
 1397
 0.51
chr17_28176724_28177079 0.23 Zfp523
 zinc finger protein 523
 228
 0.79
chr9_35558084_35558540 0.23 Ddx25
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
 216
 0.55
chr16_38741987_38742274 0.23 B4galt4
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
 134
 0.95
chr19_53661907_53662408 0.23 Rbm20
 RNA binding motif protein 20
 15149
 0.16
chr5_145191000_145191535 0.22 Atp5j2
 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
 244
 0.85
chr1_180387684_180387967 0.22 Gm36933
 predicted gene, 36933
 11381
 0.14
chr14_80901423_80902185 0.22 Gm49044
 predicted gene, 49044
 28933
 0.21
chr2_51753080_51753275 0.22 Gm13490
 predicted gene 13490
 21168
 0.21
chr5_80706733_80706963 0.22 Gm22974
 predicted gene, 22974
 186806
 0.03
chr9_78447914_78448215 0.21 Mto1
 mitochondrial tRNA translation optimization 1
 144
 0.85
chr5_120435825_120436608 0.21 Gm27199
 predicted gene 27199
 4449
 0.14
chrX_135210129_135210918 0.20 Tceal6
 transcription elongation factor A (SII)-like 6
 164
 0.93
chr9_75313853_75314949 0.20 Gnb5
 guanine nucleotide binding protein (G protein), beta 5
 260
 0.66
chr6_85587353_85587505 0.20 Alms1
 ALMS1, centrosome and basal body associated
 102
 0.96
chr2_127008729_127009233 0.19 Ap4e1
 adaptor-related protein complex AP-4, epsilon 1
 227
 0.93
chr1_171360132_171360778 0.19 Klhdc9
 kelch domain containing 9
 343
 0.67
chr14_18271212_18271647 0.19 Rpl15
 ribosomal protein L15
 38
 0.66
chr7_127470523_127470867 0.18 Prr14
 proline rich 14
 324
 0.69
chr11_70239069_70239790 0.18 Rnasek
 ribonuclease, RNase K
 351
 0.42
chr13_64312809_64313057 0.18 Prxl2c
 peroxiredoxin like 2C
 223
 0.87
chr14_111677526_111678136 0.18 Slitrk5
 SLIT and NTRK-like family, member 5
 1982
 0.36
chr16_16896578_16897698 0.18 Ppm1f
 protein phosphatase 1F (PP2C domain containing)
 564
 0.59
chr7_4137072_4137259 0.18 Leng8
 leukocyte receptor cluster (LRC) member 8
 81
 0.7
chr2_128125371_128125665 0.18 Bcl2l11
 BCL2-like 11 (apoptosis facilitator)
 520
 0.81
chr13_77046468_77046715 0.17 Slf1
 SMC5-SMC6 complex localization factor 1
 806
 0.74
chr18_69563283_69563781 0.17 Tcf4
 transcription factor 4
 197
 0.96
chr16_50689551_50689950 0.17 Gm9575
 predicted gene 9575
 23404
 0.17
chr17_6476493_6476766 0.17 Tmem181b-ps
 transmembrane protein 181B, pseudogene
 9607
 0.17
chr7_12949824_12950412 0.17 1810019N24Rik
 RIKEN cDNA 1810019N24 gene
 52
 0.93
chr10_33083500_33083959 0.17 Trdn
 triadin
 168
 0.97
chr11_121014589_121015240 0.17 Gm11774
 predicted gene 11774
 11130
 0.09
chr19_5913025_5913204 0.17 Dpf2
 D4, zinc and double PHD fingers family 2
 104
 0.51
chr3_122274436_122274925 0.17 Dnttip2
 deoxynucleotidyltransferase, terminal, interacting protein 2
 262
 0.83
chr17_80061806_80062276 0.17 Hnrnpll
 heterogeneous nuclear ribonucleoprotein L-like
 94
 0.96
chr7_74013813_74014080 0.17 St8sia2
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
 256
 0.92
chr11_94993223_94993531 0.17 Ppp1r9b
 protein phosphatase 1, regulatory subunit 9B
 497
 0.67
chr7_57386487_57387529 0.17 Gabrg3
 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
 137
 0.68
chr11_53707522_53707690 0.17 Rad50
 RAD50 double strand break repair protein
 287
 0.84
chr2_30285852_30286279 0.17 Dolk
 dolichol kinase
 269
 0.52
chr6_113482507_113483177 0.17 Creld1
 cysteine-rich with EGF-like domains 1
 455
 0.61
chr12_112644112_112644465 0.16 Siva1
 SIVA1, apoptosis-inducing factor
 391
 0.74
chrX_74085086_74085553 0.16 Mecp2
 methyl CpG binding protein 2
 278
 0.86
chr9_13297922_13298581 0.16 Maml2
 mastermind like transcriptional coactivator 2
 294
 0.88
chr9_42264436_42264649 0.16 Sc5d
 sterol-C5-desaturase
 286
 0.9
chr3_52180562_52180887 0.16 Gm30074
 predicted gene, 30074
 752
 0.55
chr8_17534365_17535810 0.16 Csmd1
 CUB and Sushi multiple domains 1
 194
 0.97
chr1_57429727_57430347 0.16 Gm22371
 predicted gene, 22371
 7664
 0.15
chr3_62603065_62604257 0.16 Gpr149
 G protein-coupled receptor 149
 887
 0.72
chr7_125445497_125445648 0.16 Kdm8
 lysine (K)-specific demethylase 8
 888
 0.57
chr18_65490174_65490449 0.16 Gm50246
 predicted gene, 50246
 11095
 0.13
chr2_180953875_180955091 0.16 Gm14341
 predicted gene 14341
 19
 0.62
chr8_63951776_63952541 0.16 Sgo2b
 shugoshin 2B
 12
 0.98
chr11_43834010_43835381 0.16 Adra1b
 adrenergic receptor, alpha 1b
 1637
 0.47
chr3_158561890_158562423 0.15 Lrrc7
 leucine rich repeat containing 7
 22
 0.99
chr1_93511429_93512004 0.15 Farp2
 FERM, RhoGEF and pleckstrin domain protein 2
 363
 0.82
chr8_113635587_113636301 0.15 Mon1b
 MON1 homolog B, secretory traffciking associated
 109
 0.96
chr6_38552191_38552670 0.15 Luc7l2
 LUC7-like 2 (S. cerevisiae)
 587
 0.68
chr2_181864457_181865175 0.15 Polr3k
 polymerase (RNA) III (DNA directed) polypeptide K
 456
 0.79
chr6_112929880_112930575 0.15 Srgap3
 SLIT-ROBO Rho GTPase activating protein 3
 16527
 0.14
chr17_46856362_46856796 0.15 Bicral
 BRD4 interacting chromatin remodeling complex associated protein like
 1903
 0.28
chr8_70896352_70896974 0.15 Rpl18a
 ribosomal protein L18A
 620
 0.33
chr16_32658548_32658939 0.15 Tnk2
 tyrosine kinase, non-receptor, 2
 182
 0.93
chr4_13754294_13755025 0.15 Runx1t1
 RUNX1 translocation partner 1
 3362
 0.37
chr9_47533054_47533827 0.15 Cadm1
 cell adhesion molecule 1
 3067
 0.25
chr15_44787203_44788294 0.15 A930017M01Rik
 RIKEN cDNA A930017M01 gene
 21
 0.83
chr9_27027276_27028031 0.15 Vps26b
 VPS26 retromer complex component B
 2377
 0.17
chr2_64853261_64853765 0.15 Gm13578
 predicted gene 13578
 15075
 0.27
chr15_27467790_27468148 0.15 Ank
 progressive ankylosis
 1292
 0.39
chr5_120711312_120711715 0.14 Dtx1
 deltex 1, E3 ubiquitin ligase
 414
 0.73
chr14_26639283_26639494 0.14 Arf4
 ADP-ribosylation factor 4
 1041
 0.32
chr4_155891860_155892180 0.14 Acap3
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
 118
 0.64
chr1_55088037_55088229 0.14 Hspe1
 heat shock protein 1 (chaperonin 10)
 1
 0.59
chr11_41999400_42000640 0.14 Gabrg2
 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
 336
 0.92
chrX_102020230_102020400 0.14 Gm27843
 predicted gene, 27843
 7163
 0.16
chr11_100738402_100738693 0.14 Rab5c
 RAB5C, member RAS oncogene family
 332
 0.77
chr15_72807706_72808811 0.14 Peg13
 paternally expressed 13
 2066
 0.4
chr17_25239740_25240111 0.14 Gnptg
 N-acetylglucosamine-1-phosphotransferase, gamma subunit
 191
 0.53
chr19_6241712_6242757 0.14 Atg2a
 autophagy related 2A
 566
 0.52
chr7_36604988_36605635 0.14 Gm29129
 predicted gene 29129
 36568
 0.17
chr4_82509049_82510307 0.14 Gm11266
 predicted gene 11266
 1662
 0.38
chr4_43499187_43499622 0.14 Arhgef39
 Rho guanine nucleotide exchange factor (GEF) 39
 204
 0.84
chr8_87974200_87975457 0.14 Zfp423
 zinc finger protein 423
 15233
 0.24
chr11_101641133_101641480 0.14 Gm24950
 predicted gene, 24950
 442
 0.64
chr11_46057942_46058389 0.14 Adam19
 a disintegrin and metallopeptidase domain 19 (meltrin beta)
 2107
 0.23
chr12_9029981_9031052 0.14 Ttc32
 tetratricopeptide repeat domain 32
 488
 0.82
chr4_13749333_13749927 0.14 Runx1t1
 RUNX1 translocation partner 1
 1667
 0.52
chr12_113140557_113141515 0.14 Crip2
 cysteine rich protein 2
 464
 0.68
chr13_48261032_48261213 0.14 Id4
 inhibitor of DNA binding 4
 106
 0.92
chr11_84915695_84916573 0.14 Znhit3
 zinc finger, HIT type 3
 171
 0.93
chr11_70240387_70240647 0.14 Rnasek
 ribonuclease, RNase K
 675
 0.3
chr14_51089768_51090539 0.13 Rnase4
 ribonuclease, RNase A family 4
 924
 0.27
chr6_128803150_128803507 0.13 Klrb1c
 killer cell lectin-like receptor subfamily B member 1C
 14113
 0.09
chr8_84102100_84102251 0.13 Dcaf15
 DDB1 and CUL4 associated factor 15
 2587
 0.11
chr7_47050631_47051464 0.13 Tmem86a
 transmembrane protein 86A
 446
 0.55
chr6_7693227_7693490 0.13 Asns
 asparagine synthetase
 104
 0.97
chr13_77975252_77975403 0.13 Pou5f2
 POU domain class 5, transcription factor 2
 49575
 0.15
chr3_131564120_131564526 0.13 Papss1
 3'-phosphoadenosine 5'-phosphosulfate synthase 1
 445
 0.87
chr10_81192796_81193377 0.13 Atcayos
 ataxia, cerebellar, Cayman type, opposite strand
 1523
 0.14
chr3_51415620_51415911 0.13 Naa15
 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
 251
 0.84
chr4_122958691_122959270 0.13 Mfsd2a
 major facilitator superfamily domain containing 2A
 1010
 0.42
chr3_95928548_95928975 0.13 Anp32e
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
 485
 0.63
chr1_77501424_77502014 0.13 Mir6352
 microRNA 6352
 4951
 0.21
chr19_45812760_45812972 0.13 Kcnip2
 Kv channel-interacting protein 2
 575
 0.7
chr5_108629016_108629687 0.13 Gak
 cyclin G associated kinase
 72
 0.84
chr16_94996546_94998023 0.13 Kcnj6
 potassium inwardly-rectifying channel, subfamily J, member 6
 32
 0.99
chr4_102254418_102255744 0.13 Pde4b
 phosphodiesterase 4B, cAMP specific
 78
 0.99
chr15_83172415_83172866 0.12 Cyb5r3
 cytochrome b5 reductase 3
 48
 0.78
chr6_113442622_113443115 0.12 Jagn1
 jagunal homolog 1
 258
 0.77
chr17_56141491_56142567 0.12 Sema6b
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 1686
 0.19
chr5_111421306_111422790 0.12 Gm43119
 predicted gene 43119
 1541
 0.35
chr7_112954380_112955414 0.12 Rassf10
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
 935
 0.58
chr1_65178523_65179140 0.12 Idh1
 isocitrate dehydrogenase 1 (NADP+), soluble
 350
 0.84
chr2_66408526_66409644 0.12 Gm13630
 predicted gene 13630
 409
 0.72
chr7_79148061_79149306 0.12 Mfge8
 milk fat globule-EGF factor 8 protein
 306
 0.89
chr11_101646166_101646629 0.12 Gm23971
 predicted gene, 23971
 467
 0.62
chr16_32099114_32099696 0.12 Pigx
 phosphatidylinositol glycan anchor biosynthesis, class X
 288
 0.56
chr6_97938208_97938822 0.12 Mitf
 melanogenesis associated transcription factor
 2403
 0.38
chr6_122309029_122310024 0.12 M6pr
 mannose-6-phosphate receptor, cation dependent
 527
 0.67
chr11_98981811_98983058 0.12 Gjd3
 gap junction protein, delta 3
 582
 0.6
chr6_121184526_121184909 0.12 Pex26
 peroxisomal biogenesis factor 26
 819
 0.52
chr11_47988311_47989415 0.12 Sgcd
 sarcoglycan, delta (dystrophin-associated glycoprotein)
 106
 0.98
chr16_11176493_11176867 0.12 Zc3h7a
 zinc finger CCCH type containing 7 A
 287
 0.77
chr4_156035263_156035900 0.12 Gm16008
 predicted gene 16008
 3938
 0.08
chr12_83987542_83988596 0.12 Acot2
 acyl-CoA thioesterase 2
 208
 0.87
chr18_3507019_3507669 0.12 Bambi
 BMP and activin membrane-bound inhibitor
 579
 0.7
chrX_12916494_12917181 0.12 Gm14524
 predicted gene 14524
 2245
 0.27
chr4_86734155_86734345 0.12 Dennd4c
 DENN/MADD domain containing 4C
 14305
 0.2
chr17_8368706_8369049 0.12 T2
 brachyury 2
 3519
 0.15
chr9_122571597_122571748 0.11 9530059O14Rik
 RIKEN cDNA 9530059O14 gene
 827
 0.55
chr11_69991633_69992222 0.11 Gabarap
 gamma-aminobutyric acid receptor associated protein
 120
 0.87
chr18_66291045_66291813 0.11 Ccbe1
 collagen and calcium binding EGF domains 1
 17
 0.66
chr13_99724294_99724631 0.11 Gm24471
 predicted gene, 24471
 31933
 0.2
chr4_120715702_120717192 0.11 Kcnq4
 potassium voltage-gated channel, subfamily Q, member 4
 30801
 0.11
chr11_60178073_60178451 0.11 Rai1
 retinoic acid induced 1
 2383
 0.2
chr8_86624092_86625039 0.11 Lonp2
 lon peptidase 2, peroxisomal
 460
 0.8
chr2_164910537_164911246 0.11 Zfp335os
 zinc finger protein 335, opposite strand
 463
 0.57
chr15_81872520_81873197 0.11 Aco2
 aconitase 2, mitochondrial
 168
 0.85
chr1_189921588_189922055 0.11 Smyd2
 SET and MYND domain containing 2
 432
 0.82
chr3_8923882_8924255 0.11 Mrps28
 mitochondrial ribosomal protein S28
 150
 0.96
chr3_70874375_70874526 0.11 Gm10780
 predicted gene 10780
 185358
 0.03
chr13_43158853_43159330 0.11 Tbc1d7
 TBC1 domain family, member 7
 217
 0.94
chr11_116652562_116653193 0.11 Prcd
 photoreceptor disc component
 657
 0.45
chr5_111429061_111430219 0.11 Gm43119
 predicted gene 43119
 6051
 0.18
chr11_116586983_116587414 0.11 Aanat
 arylalkylamine N-acetyltransferase
 766
 0.46
chr4_82489730_82490472 0.11 Nfib
 nuclear factor I/B
 9215
 0.21
chr7_133776817_133777117 0.11 Fank1
 fibronectin type 3 and ankyrin repeat domains 1
 25
 0.67
chr8_14384129_14384280 0.11 Dlgap2
 DLG associated protein 2
 2208
 0.37
chr2_71983646_71983797 0.11 Rapgef4
 Rap guanine nucleotide exchange factor (GEF) 4
 2434
 0.28
chr7_110163999_110164879 0.11 1600010M07Rik
 RIKEN cDNA 1600010M07 gene
 13237
 0.15
chr4_137388448_137388745 0.11 2810405F17Rik
 RIKEN cDNA 2810405F17 gene
 214
 0.89
chr11_50210297_50211093 0.10 Sqstm1
 sequestosome 1
 70
 0.67
chr2_116063125_116063508 0.10 Meis2
 Meis homeobox 2
 786
 0.59
chr11_76763713_76763912 0.10 Gosr1
 golgi SNAP receptor complex member 1
 233
 0.93
chr2_152395546_152396207 0.10 Sox12
 SRY (sex determining region Y)-box 12
 2170
 0.15
chr1_93100315_93101980 0.10 Kif1a
 kinesin family member 1A
 675
 0.62
chr11_28365090_28365896 0.10 Gm12081
 predicted gene 12081
 5131
 0.26
chr1_139929330_139929725 0.10 Gm5837
 predicted gene 5837
 81
 0.97
chr2_153071959_153072358 0.10 Ccm2l
 cerebral cavernous malformation 2-like
 6156
 0.15
chr2_174463176_174464054 0.10 Atp5e
 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
 434
 0.73
chr1_95666998_95667591 0.10 St8sia4
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
 241
 0.93
chr10_5824069_5824916 0.10 Mtrf1l
 mitochondrial translational release factor 1-like
 582
 0.79
chr9_96733821_96734335 0.10 Zbtb38
 zinc finger and BTB domain containing 38
 1308
 0.4
chr13_54621866_54622790 0.10 Faf2
 Fas associated factor family member 2
 490
 0.69
chr7_141228533_141229727 0.10 Phrf1
 PHD and ring finger domains 1
 341
 0.71
chr18_37496992_37497992 0.10 Pcdhb19
 protocadherin beta 19
 501
 0.54
chr1_190911845_190912265 0.10 Rps6kc1
 ribosomal protein S6 kinase polypeptide 1
 285
 0.89
chr19_3768976_3769359 0.10 Kmt5b
 lysine methyltransferase 5B
 620
 0.58
chr11_3451898_3452279 0.10 Rnf185
 ring finger protein 185
 246
 0.5
chr9_72985588_72986210 0.10 Ccpg1
 cell cycle progression 1
 280
 0.62
chr3_105053107_105053623 0.10 Cttnbp2nl
 CTTNBP2 N-terminal like
 219
 0.93
chr1_152399580_152399796 0.10 Colgalt2
 collagen beta(1-O)galactosyltransferase 2
 142
 0.96
chr19_49741229_49741380 0.10 Gm6975
 predicted gene 6975
 31180
 0.19
chr3_57735567_57735933 0.10 Rnf13
 ring finger protein 13
 312
 0.85
chr13_51848386_51848617 0.10 Gadd45g
 growth arrest and DNA-damage-inducible 45 gamma
 1757
 0.42
chr17_34204505_34204720 0.10 Tap2
 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
 45
 0.88

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxn1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.3 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.1 0.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.3 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.2 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0 0.1 GO:0019230 proprioception(GO:0019230)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.3 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.0 GO:1902488 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.0 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.0 GO:0060486 Clara cell differentiation(GO:0060486)
0.0 0.2 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0 0.1 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0008355 olfactory learning(GO:0008355)
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.0 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0008251 tRNA-specific adenosine deaminase activity(GO:0008251)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.0 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins