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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Foxn1

Z-value: 0.43

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Transcription factors associated with Foxn1

Gene Symbol	Gene ID	Gene Info
Foxn1 Ensembl NCBI MGI UniProt	ENSMUSG00000002057.4	Foxn1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Foxn1	chr11_78384887_78385288	1471	0.236917	-0.22	9.8e-02	Click!
Foxn1	chr11_78386075_78386548	247	0.847600	-0.20	1.2e-01	Click!
Foxn1	chr11_78383526_78383677	2957	0.133104	-0.15	2.5e-01	Click!
Foxn1	chr11_78378001_78378152	8482	0.094759	-0.08	5.3e-01	Click!
Foxn1	chr11_78385731_78386019	683	0.508496	-0.06	6.2e-01	Click!

Activity of the Foxn1 motif across conditions

Conditions sorted by the z-value of the Foxn1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr13_83721518_83722206	0.52	C130071C03Rik	RIKEN cDNA C130071C03 gene	481	0.73
chrX_23285148_23285871	0.43	Klhl13	kelch-like 13	50	0.99
chr10_34301557_34301950	0.42	Tspyl4	TSPY-like 4	2497	0.16
chr9_96758931_96759244	0.41	Zbtb38	zinc finger and BTB domain containing 38	6256	0.16
chr5_22746211_22746970	0.38	A930003O13Rik	RIKEN cDNA A930003O13 gene	297	0.65
chr9_113708285_113708476	0.38	Pdcd6ip	programmed cell death 6 interacting protein	121	0.97
chr2_20966052_20966447	0.35	Arhgap21	Rho GTPase activating protein 21	1471	0.39
chr13_13785297_13785737	0.35	Gng4	guanine nucleotide binding protein (G protein), gamma 4	1188	0.47
chr8_123333278_123333633	0.33	Spire2	spire type actin nucleation factor 2	742	0.47
chr2_126675916_126676238	0.32	Gm27003	predicted gene, 27003	161	0.62
chr14_70577418_70577686	0.32	Nudt18	nudix (nucleoside diphosphate linked moiety X)-type motif 18	85	0.95
chr7_36705087_36705327	0.31	Gm37452	predicted gene, 37452	4967	0.15
chr10_40257841_40258099	0.31	Gtf3c6	general transcription factor IIIC, polypeptide 6, alpha	138	0.81
chr19_27217816_27218252	0.31	Vldlr	very low density lipoprotein receptor	576	0.77
chr6_105676979_105678296	0.29	Cntn4	contactin 4	23	0.52
chr9_62040106_62040360	0.29	Paqr5	progestin and adipoQ receptor family member V	13377	0.2
chr6_121183940_121184503	0.29	Pex26	peroxisomal biogenesis factor 26	323	0.84
chr1_188003839_188004226	0.28	9330162B11Rik	RIKEN cDNA 9330162B11 gene	4958	0.26
chr8_104629629_104629943	0.27	Gm33023	predicted gene, 33023	1046	0.27
chr18_11657869_11658260	0.27	Rbbp8	retinoblastoma binding protein 8, endonuclease	222	0.57
chr8_87539918_87540560	0.27	4933402J07Rik	RIKEN cDNA 4933402J07 gene	23614	0.14
chr14_55055435_55055869	0.26	Gm20687	predicted gene 20687	159	0.87
chr17_34295833_34296830	0.26	H2-Aa	histocompatibility 2, class II antigen A, alpha	8508	0.08
chr12_5373600_5373751	0.26	Klhl29	kelch-like 29	2007	0.33
chr17_55447566_55447717	0.25	St6gal2	beta galactoside alpha 2,6 sialyltransferase 2	1397	0.51
chr17_28176724_28177079	0.23	Zfp523	zinc finger protein 523	228	0.79
chr9_35558084_35558540	0.23	Ddx25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25	216	0.55
chr16_38741987_38742274	0.23	B4galt4	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4	134	0.95
chr19_53661907_53662408	0.23	Rbm20	RNA binding motif protein 20	15149	0.16
chr5_145191000_145191535	0.22	Atp5j2	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2	244	0.85
chr1_180387684_180387967	0.22	Gm36933	predicted gene, 36933	11381	0.14
chr14_80901423_80902185	0.22	Gm49044	predicted gene, 49044	28933	0.21
chr2_51753080_51753275	0.22	Gm13490	predicted gene 13490	21168	0.21
chr5_80706733_80706963	0.22	Gm22974	predicted gene, 22974	186806	0.03
chr9_78447914_78448215	0.21	Mto1	mitochondrial tRNA translation optimization 1	144	0.85
chr5_120435825_120436608	0.21	Gm27199	predicted gene 27199	4449	0.14
chrX_135210129_135210918	0.20	Tceal6	transcription elongation factor A (SII)-like 6	164	0.93
chr9_75313853_75314949	0.20	Gnb5	guanine nucleotide binding protein (G protein), beta 5	260	0.66
chr6_85587353_85587505	0.20	Alms1	ALMS1, centrosome and basal body associated	102	0.96
chr2_127008729_127009233	0.19	Ap4e1	adaptor-related protein complex AP-4, epsilon 1	227	0.93
chr1_171360132_171360778	0.19	Klhdc9	kelch domain containing 9	343	0.67
chr14_18271212_18271647	0.19	Rpl15	ribosomal protein L15	38	0.66
chr7_127470523_127470867	0.18	Prr14	proline rich 14	324	0.69
chr11_70239069_70239790	0.18	Rnasek	ribonuclease, RNase K	351	0.42
chr13_64312809_64313057	0.18	Prxl2c	peroxiredoxin like 2C	223	0.87
chr14_111677526_111678136	0.18	Slitrk5	SLIT and NTRK-like family, member 5	1982	0.36
chr16_16896578_16897698	0.18	Ppm1f	protein phosphatase 1F (PP2C domain containing)	564	0.59
chr7_4137072_4137259	0.18	Leng8	leukocyte receptor cluster (LRC) member 8	81	0.7
chr2_128125371_128125665	0.18	Bcl2l11	BCL2-like 11 (apoptosis facilitator)	520	0.81
chr13_77046468_77046715	0.17	Slf1	SMC5-SMC6 complex localization factor 1	806	0.74
chr18_69563283_69563781	0.17	Tcf4	transcription factor 4	197	0.96
chr16_50689551_50689950	0.17	Gm9575	predicted gene 9575	23404	0.17
chr17_6476493_6476766	0.17	Tmem181b-ps	transmembrane protein 181B, pseudogene	9607	0.17
chr7_12949824_12950412	0.17	1810019N24Rik	RIKEN cDNA 1810019N24 gene	52	0.93
chr10_33083500_33083959	0.17	Trdn	triadin	168	0.97
chr11_121014589_121015240	0.17	Gm11774	predicted gene 11774	11130	0.09
chr19_5913025_5913204	0.17	Dpf2	D4, zinc and double PHD fingers family 2	104	0.51
chr3_122274436_122274925	0.17	Dnttip2	deoxynucleotidyltransferase, terminal, interacting protein 2	262	0.83
chr17_80061806_80062276	0.17	Hnrnpll	heterogeneous nuclear ribonucleoprotein L-like	94	0.96
chr7_74013813_74014080	0.17	St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	256	0.92
chr11_94993223_94993531	0.17	Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	497	0.67
chr7_57386487_57387529	0.17	Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	137	0.68
chr11_53707522_53707690	0.17	Rad50	RAD50 double strand break repair protein	287	0.84
chr2_30285852_30286279	0.17	Dolk	dolichol kinase	269	0.52
chr6_113482507_113483177	0.17	Creld1	cysteine-rich with EGF-like domains 1	455	0.61
chr12_112644112_112644465	0.16	Siva1	SIVA1, apoptosis-inducing factor	391	0.74
chrX_74085086_74085553	0.16	Mecp2	methyl CpG binding protein 2	278	0.86
chr9_13297922_13298581	0.16	Maml2	mastermind like transcriptional coactivator 2	294	0.88
chr9_42264436_42264649	0.16	Sc5d	sterol-C5-desaturase	286	0.9
chr3_52180562_52180887	0.16	Gm30074	predicted gene, 30074	752	0.55
chr8_17534365_17535810	0.16	Csmd1	CUB and Sushi multiple domains 1	194	0.97
chr1_57429727_57430347	0.16	Gm22371	predicted gene, 22371	7664	0.15
chr3_62603065_62604257	0.16	Gpr149	G protein-coupled receptor 149	887	0.72
chr7_125445497_125445648	0.16	Kdm8	lysine (K)-specific demethylase 8	888	0.57
chr18_65490174_65490449	0.16	Gm50246	predicted gene, 50246	11095	0.13
chr2_180953875_180955091	0.16	Gm14341	predicted gene 14341	19	0.62
chr8_63951776_63952541	0.16	Sgo2b	shugoshin 2B	12	0.98
chr11_43834010_43835381	0.16	Adra1b	adrenergic receptor, alpha 1b	1637	0.47
chr3_158561890_158562423	0.15	Lrrc7	leucine rich repeat containing 7	22	0.99
chr1_93511429_93512004	0.15	Farp2	FERM, RhoGEF and pleckstrin domain protein 2	363	0.82
chr8_113635587_113636301	0.15	Mon1b	MON1 homolog B, secretory traffciking associated	109	0.96
chr6_38552191_38552670	0.15	Luc7l2	LUC7-like 2 (S. cerevisiae)	587	0.68
chr2_181864457_181865175	0.15	Polr3k	polymerase (RNA) III (DNA directed) polypeptide K	456	0.79
chr6_112929880_112930575	0.15	Srgap3	SLIT-ROBO Rho GTPase activating protein 3	16527	0.14
chr17_46856362_46856796	0.15	Bicral	BRD4 interacting chromatin remodeling complex associated protein like	1903	0.28
chr8_70896352_70896974	0.15	Rpl18a	ribosomal protein L18A	620	0.33
chr16_32658548_32658939	0.15	Tnk2	tyrosine kinase, non-receptor, 2	182	0.93
chr4_13754294_13755025	0.15	Runx1t1	RUNX1 translocation partner 1	3362	0.37
chr9_47533054_47533827	0.15	Cadm1	cell adhesion molecule 1	3067	0.25
chr15_44787203_44788294	0.15	A930017M01Rik	RIKEN cDNA A930017M01 gene	21	0.83
chr9_27027276_27028031	0.15	Vps26b	VPS26 retromer complex component B	2377	0.17
chr2_64853261_64853765	0.15	Gm13578	predicted gene 13578	15075	0.27
chr15_27467790_27468148	0.15	Ank	progressive ankylosis	1292	0.39
chr5_120711312_120711715	0.14	Dtx1	deltex 1, E3 ubiquitin ligase	414	0.73
chr14_26639283_26639494	0.14	Arf4	ADP-ribosylation factor 4	1041	0.32
chr4_155891860_155892180	0.14	Acap3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	118	0.64
chr1_55088037_55088229	0.14	Hspe1	heat shock protein 1 (chaperonin 10)	1	0.59
chr11_41999400_42000640	0.14	Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	336	0.92
chrX_102020230_102020400	0.14	Gm27843	predicted gene, 27843	7163	0.16
chr11_100738402_100738693	0.14	Rab5c	RAB5C, member RAS oncogene family	332	0.77
chr15_72807706_72808811	0.14	Peg13	paternally expressed 13	2066	0.4
chr17_25239740_25240111	0.14	Gnptg	N-acetylglucosamine-1-phosphotransferase, gamma subunit	191	0.53
chr19_6241712_6242757	0.14	Atg2a	autophagy related 2A	566	0.52
chr7_36604988_36605635	0.14	Gm29129	predicted gene 29129	36568	0.17
chr4_82509049_82510307	0.14	Gm11266	predicted gene 11266	1662	0.38
chr4_43499187_43499622	0.14	Arhgef39	Rho guanine nucleotide exchange factor (GEF) 39	204	0.84
chr8_87974200_87975457	0.14	Zfp423	zinc finger protein 423	15233	0.24
chr11_101641133_101641480	0.14	Gm24950	predicted gene, 24950	442	0.64
chr11_46057942_46058389	0.14	Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	2107	0.23
chr12_9029981_9031052	0.14	Ttc32	tetratricopeptide repeat domain 32	488	0.82
chr4_13749333_13749927	0.14	Runx1t1	RUNX1 translocation partner 1	1667	0.52
chr12_113140557_113141515	0.14	Crip2	cysteine rich protein 2	464	0.68
chr13_48261032_48261213	0.14	Id4	inhibitor of DNA binding 4	106	0.92
chr11_84915695_84916573	0.14	Znhit3	zinc finger, HIT type 3	171	0.93
chr11_70240387_70240647	0.14	Rnasek	ribonuclease, RNase K	675	0.3
chr14_51089768_51090539	0.13	Rnase4	ribonuclease, RNase A family 4	924	0.27
chr6_128803150_128803507	0.13	Klrb1c	killer cell lectin-like receptor subfamily B member 1C	14113	0.09
chr8_84102100_84102251	0.13	Dcaf15	DDB1 and CUL4 associated factor 15	2587	0.11
chr7_47050631_47051464	0.13	Tmem86a	transmembrane protein 86A	446	0.55
chr6_7693227_7693490	0.13	Asns	asparagine synthetase	104	0.97
chr13_77975252_77975403	0.13	Pou5f2	POU domain class 5, transcription factor 2	49575	0.15
chr3_131564120_131564526	0.13	Papss1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	445	0.87
chr10_81192796_81193377	0.13	Atcayos	ataxia, cerebellar, Cayman type, opposite strand	1523	0.14
chr3_51415620_51415911	0.13	Naa15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	251	0.84
chr4_122958691_122959270	0.13	Mfsd2a	major facilitator superfamily domain containing 2A	1010	0.42
chr3_95928548_95928975	0.13	Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	485	0.63
chr1_77501424_77502014	0.13	Mir6352	microRNA 6352	4951	0.21
chr19_45812760_45812972	0.13	Kcnip2	Kv channel-interacting protein 2	575	0.7
chr5_108629016_108629687	0.13	Gak	cyclin G associated kinase	72	0.84
chr16_94996546_94998023	0.13	Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	32	0.99
chr4_102254418_102255744	0.13	Pde4b	phosphodiesterase 4B, cAMP specific	78	0.99
chr15_83172415_83172866	0.12	Cyb5r3	cytochrome b5 reductase 3	48	0.78
chr6_113442622_113443115	0.12	Jagn1	jagunal homolog 1	258	0.77
chr17_56141491_56142567	0.12	Sema6b	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	1686	0.19
chr5_111421306_111422790	0.12	Gm43119	predicted gene 43119	1541	0.35
chr7_112954380_112955414	0.12	Rassf10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10	935	0.58
chr1_65178523_65179140	0.12	Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	350	0.84
chr2_66408526_66409644	0.12	Gm13630	predicted gene 13630	409	0.72
chr7_79148061_79149306	0.12	Mfge8	milk fat globule-EGF factor 8 protein	306	0.89
chr11_101646166_101646629	0.12	Gm23971	predicted gene, 23971	467	0.62
chr16_32099114_32099696	0.12	Pigx	phosphatidylinositol glycan anchor biosynthesis, class X	288	0.56
chr6_97938208_97938822	0.12	Mitf	melanogenesis associated transcription factor	2403	0.38
chr6_122309029_122310024	0.12	M6pr	mannose-6-phosphate receptor, cation dependent	527	0.67
chr11_98981811_98983058	0.12	Gjd3	gap junction protein, delta 3	582	0.6
chr6_121184526_121184909	0.12	Pex26	peroxisomal biogenesis factor 26	819	0.52
chr11_47988311_47989415	0.12	Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	106	0.98
chr16_11176493_11176867	0.12	Zc3h7a	zinc finger CCCH type containing 7 A	287	0.77
chr4_156035263_156035900	0.12	Gm16008	predicted gene 16008	3938	0.08
chr12_83987542_83988596	0.12	Acot2	acyl-CoA thioesterase 2	208	0.87
chr18_3507019_3507669	0.12	Bambi	BMP and activin membrane-bound inhibitor	579	0.7
chrX_12916494_12917181	0.12	Gm14524	predicted gene 14524	2245	0.27
chr4_86734155_86734345	0.12	Dennd4c	DENN/MADD domain containing 4C	14305	0.2
chr17_8368706_8369049	0.12	T2	brachyury 2	3519	0.15
chr9_122571597_122571748	0.11	9530059O14Rik	RIKEN cDNA 9530059O14 gene	827	0.55
chr11_69991633_69992222	0.11	Gabarap	gamma-aminobutyric acid receptor associated protein	120	0.87
chr18_66291045_66291813	0.11	Ccbe1	collagen and calcium binding EGF domains 1	17	0.66
chr13_99724294_99724631	0.11	Gm24471	predicted gene, 24471	31933	0.2
chr4_120715702_120717192	0.11	Kcnq4	potassium voltage-gated channel, subfamily Q, member 4	30801	0.11
chr11_60178073_60178451	0.11	Rai1	retinoic acid induced 1	2383	0.2
chr8_86624092_86625039	0.11	Lonp2	lon peptidase 2, peroxisomal	460	0.8
chr2_164910537_164911246	0.11	Zfp335os	zinc finger protein 335, opposite strand	463	0.57
chr15_81872520_81873197	0.11	Aco2	aconitase 2, mitochondrial	168	0.85
chr1_189921588_189922055	0.11	Smyd2	SET and MYND domain containing 2	432	0.82
chr3_8923882_8924255	0.11	Mrps28	mitochondrial ribosomal protein S28	150	0.96
chr3_70874375_70874526	0.11	Gm10780	predicted gene 10780	185358	0.03
chr13_43158853_43159330	0.11	Tbc1d7	TBC1 domain family, member 7	217	0.94
chr11_116652562_116653193	0.11	Prcd	photoreceptor disc component	657	0.45
chr5_111429061_111430219	0.11	Gm43119	predicted gene 43119	6051	0.18
chr11_116586983_116587414	0.11	Aanat	arylalkylamine N-acetyltransferase	766	0.46
chr4_82489730_82490472	0.11	Nfib	nuclear factor I/B	9215	0.21
chr7_133776817_133777117	0.11	Fank1	fibronectin type 3 and ankyrin repeat domains 1	25	0.67
chr8_14384129_14384280	0.11	Dlgap2	DLG associated protein 2	2208	0.37
chr2_71983646_71983797	0.11	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	2434	0.28
chr7_110163999_110164879	0.11	1600010M07Rik	RIKEN cDNA 1600010M07 gene	13237	0.15
chr4_137388448_137388745	0.11	2810405F17Rik	RIKEN cDNA 2810405F17 gene	214	0.89
chr11_50210297_50211093	0.10	Sqstm1	sequestosome 1	70	0.67
chr2_116063125_116063508	0.10	Meis2	Meis homeobox 2	786	0.59
chr11_76763713_76763912	0.10	Gosr1	golgi SNAP receptor complex member 1	233	0.93
chr2_152395546_152396207	0.10	Sox12	SRY (sex determining region Y)-box 12	2170	0.15
chr1_93100315_93101980	0.10	Kif1a	kinesin family member 1A	675	0.62
chr11_28365090_28365896	0.10	Gm12081	predicted gene 12081	5131	0.26
chr1_139929330_139929725	0.10	Gm5837	predicted gene 5837	81	0.97
chr2_153071959_153072358	0.10	Ccm2l	cerebral cavernous malformation 2-like	6156	0.15
chr2_174463176_174464054	0.10	Atp5e	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit	434	0.73
chr1_95666998_95667591	0.10	St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	241	0.93
chr10_5824069_5824916	0.10	Mtrf1l	mitochondrial translational release factor 1-like	582	0.79
chr9_96733821_96734335	0.10	Zbtb38	zinc finger and BTB domain containing 38	1308	0.4
chr13_54621866_54622790	0.10	Faf2	Fas associated factor family member 2	490	0.69
chr7_141228533_141229727	0.10	Phrf1	PHD and ring finger domains 1	341	0.71
chr18_37496992_37497992	0.10	Pcdhb19	protocadherin beta 19	501	0.54
chr1_190911845_190912265	0.10	Rps6kc1	ribosomal protein S6 kinase polypeptide 1	285	0.89
chr19_3768976_3769359	0.10	Kmt5b	lysine methyltransferase 5B	620	0.58
chr11_3451898_3452279	0.10	Rnf185	ring finger protein 185	246	0.5
chr9_72985588_72986210	0.10	Ccpg1	cell cycle progression 1	280	0.62
chr3_105053107_105053623	0.10	Cttnbp2nl	CTTNBP2 N-terminal like	219	0.93
chr1_152399580_152399796	0.10	Colgalt2	collagen beta(1-O)galactosyltransferase 2	142	0.96
chr19_49741229_49741380	0.10	Gm6975	predicted gene 6975	31180	0.19
chr3_57735567_57735933	0.10	Rnf13	ring finger protein 13	312	0.85
chr13_51848386_51848617	0.10	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	1757	0.42
chr17_34204505_34204720	0.10	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	45	0.88

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxn1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0034436	glycoprotein transport(GO:0034436)
0.1	0.3	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.1	0.4	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.1	0.2	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.1	0.3	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1	0.2	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.2	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.2	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0	0.1	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.1	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0	0.1	GO:0019230	proprioception(GO:0019230)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.3	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
0.0	0.1	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0	0.0	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.1	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.0	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.0	0.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.1	GO:0021764	amygdala development(GO:0021764)
0.0	0.0	GO:0060486	Clara cell differentiation(GO:0060486)
0.0	0.2	GO:0043574	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0	0.1	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0	0.1	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.1	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.1	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.2	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.0	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.0	0.2	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0061074	regulation of neural retina development(GO:0061074)
0.0	0.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.4	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.0	GO:0001827	inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0	0.1	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.1	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.4	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.0	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.2	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0002081	outer acrosomal membrane(GO:0002081)
0.0	0.2	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.0	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.2	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.2	GO:0097225	sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	0.2	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.3	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0034951	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0008251	tRNA-specific adenosine deaminase activity(GO:0008251)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.1	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.0	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.2	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	PID ATM PATHWAY	ATM pathway
0.4	PID AURORA B PATHWAY	Aurora B signaling
0.3	PID REELIN PATHWAY	Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.3	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins