Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Foxo3

Z-value: 0.55

Motif logo

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Transcription factors associated with Foxo3

Gene Symbol Gene ID Gene Info
Foxo3
ENSMUSG00000048756.5 forkhead box O3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr10_42272287_42272486Foxo343100.288598-0.392.1e-03Click!
chr10_42244059_42244384Foxo3141450.250140-0.311.6e-02Click!
chr10_42251868_42252252Foxo363060.275620-0.311.6e-02Click!
chr10_42247495_42248433Foxo3104020.259004-0.301.9e-02Click!
chr10_42262321_42262472Foxo340300.300609-0.301.9e-02Click!

Activity of the Foxo3 motif across conditions

Conditions sorted by the z-value of the Foxo3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_150261018_150262108 0.78 Fry
 FRY microtubule binding protein
 1796
 0.34
chr5_150260534_150260992 0.71 Fry
 FRY microtubule binding protein
 996
 0.55
chr8_25521556_25521707 0.60 Fgfr1
 fibroblast growth factor receptor 1
 1794
 0.24
chr18_69521278_69522871 0.60 Tcf4
 transcription factor 4
 73
 0.98
chr8_23669376_23670424 0.54 Zmat4
 zinc finger, matrin type 4
 226
 0.95
chr5_3432895_3433605 0.53 Cdk6
 cyclin-dependent kinase 6
 37699
 0.12
chr8_84765171_84766430 0.52 Nfix
 nuclear factor I/X
 7596
 0.11
chr6_55617797_55618517 0.51 Neurod6
 neurogenic differentiation 6
 63106
 0.11
chr6_8352545_8353207 0.49 Gm16055
 predicted gene 16055
 11260
 0.18
chr2_4300456_4301144 0.49 Frmd4a
 FERM domain containing 4A
 85
 0.78
chr5_57728215_57728366 0.49 Gm42635
 predicted gene 42635
 3897
 0.15
chr7_12421647_12422940 0.47 Zfp551
 zinc fingr protein 551
 146
 0.92
chr18_49543238_49543945 0.46 1700044K03Rik
 RIKEN cDNA 1700044K03 gene
 20302
 0.23
chr13_4662525_4663068 0.46 Gm40658
 predicted gene, 40658
 18889
 0.18
chr3_82141940_82142375 0.44 Gucy1a1
 guanylate cyclase 1, soluble, alpha 1
 2916
 0.3
chr6_136167149_136168437 0.42 Grin2b
 glutamate receptor, ionotropic, NMDA2B (epsilon 2)
 4096
 0.25
chr7_144132849_144134003 0.42 Gm44999
 predicted gene 44999
 22341
 0.2
chr2_27539183_27539675 0.41 Gm25541
 predicted gene, 25541
 501
 0.63
chr7_30291688_30292446 0.41 Clip3
 CAP-GLY domain containing linker protein 3
 109
 0.9
chr11_109649280_109649701 0.41 Prkar1a
 protein kinase, cAMP dependent regulatory, type I, alpha
 85
 0.97
chr5_57721137_57722906 0.40 Pcdh7
 protocadherin 7
 108
 0.94
chr3_63296309_63296634 0.39 Mme
 membrane metallo endopeptidase
 376
 0.91
chr2_20339506_20340619 0.38 Etl4
 enhancer trap locus 4
 238
 0.94
chr1_153328595_153328920 0.38 Lamc1
 laminin, gamma 1
 4029
 0.2
chr5_107167246_107168359 0.38 Gm43423
 predicted gene 43423
 7231
 0.17
chr9_10903843_10905236 0.38 Cntn5
 contactin 5
 90
 0.65
chr11_93818459_93818772 0.36 Utp18
 UTP18 small subunit processome component
 57528
 0.12
chr18_69125035_69125283 0.36 Gm23536
 predicted gene, 23536
 48961
 0.13
chr13_44946033_44946635 0.36 Dtnbp1
 dystrobrevin binding protein 1
 810
 0.7
chr1_23490694_23490976 0.36 Gm7784
 predicted gene 7784
 11296
 0.24
chr14_50896223_50897440 0.35 Klhl33
 kelch-like 33
 625
 0.49
chr18_69349496_69350227 0.35 Tcf4
 transcription factor 4
 917
 0.69
chr2_134787876_134788027 0.35 Plcb1
 phospholipase C, beta 1
 1421
 0.42
chr16_50380747_50382000 0.35 Bbx
 bobby sox HMG box containing
 48539
 0.18
chr13_93307758_93308718 0.34 Homer1
 homer scaffolding protein 1
 204
 0.92
chr9_81629834_81629994 0.34 D430036J16Rik
 RIKEN cDNA D430036J16 gene
 1637
 0.38
chr19_32866529_32866680 0.34 Pten
 phosphatase and tensin homolog
 55379
 0.14
chr8_109250884_109251908 0.33 D030068K23Rik
 RIKEN cDNA D030068K23 gene
 1530
 0.52
chr17_70521708_70522843 0.33 Dlgap1
 DLG associated protein 1
 113
 0.98
chr2_120244697_120245562 0.33 Pla2g4e
 phospholipase A2, group IVE
 21
 0.89
chr2_167233751_167233909 0.33 Ptgis
 prostaglandin I2 (prostacyclin) synthase
 6759
 0.15
chr8_45109829_45110486 0.33 Gm30504
 predicted gene, 30504
 324
 0.88
chr7_87584791_87585125 0.32 Grm5
 glutamate receptor, metabotropic 5
 560
 0.85
chr2_92198196_92198596 0.31 Mir1955
 microRNA 1955
 6419
 0.17
chr11_63412437_63413498 0.31 B130011K05Rik
 RIKEN cDNA B130011K05 gene
 202
 0.96
chr7_91092040_91092191 0.31 Dlg2
 discs large MAGUK scaffold protein 2
 1387
 0.4
chr7_109783136_109783287 0.30 Nrip3
 nuclear receptor interacting protein 3
 1186
 0.34
chr16_42782105_42782459 0.30 4932412D23Rik
 RIKEN cDNA 4932412D23 gene
 93305
 0.08
chr13_28416755_28419194 0.30 Gm40841
 predicted gene, 40841
 1889
 0.42
chr15_74679054_74679804 0.30 Arc
 activity regulated cytoskeletal-associated protein
 6859
 0.1
chr19_16061967_16062187 0.29 Rpl37-ps1
 ribosomal protein 37, pseudogene 1
 36626
 0.15
chr2_74699510_74699661 0.29 Gm44463
 predicted gene, 44463
 1557
 0.11
chr4_25798002_25798171 0.29 Fut9
 fucosyltransferase 9
 1769
 0.36
chr4_153110438_153110637 0.29 Gm13173
 predicted gene 13173
 36406
 0.21
chr1_35849717_35849997 0.29 1110002O04Rik
 RIKEN cDNA 1110002O04 gene
 29988
 0.16
chr2_96319240_96319943 0.29 Lrrc4c
 leucine rich repeat containing 4C
 1375
 0.61
chr4_137043562_137044547 0.29 Zbtb40
 zinc finger and BTB domain containing 40
 4641
 0.19
chr3_34773718_34774341 0.28 Gm38509
 predicted gene, 38509
 1954
 0.34
chrX_51678321_51678764 0.28 Hs6st2
 heparan sulfate 6-O-sulfotransferase 2
 2023
 0.41
chr2_59438036_59438472 0.28 Gm13549
 predicted gene 13549
 38473
 0.13
chr12_54702794_54702945 0.28 Rpl31-ps17
 ribosomal protein L31, pseudogene 17
 1163
 0.21
chr16_10447447_10447926 0.28 Tvp23a
 trans-golgi network vesicle protein 23A
 324
 0.87
chr15_85674019_85674170 0.28 Lncppara
 long noncoding RNA near Ppara
 20478
 0.13
chr2_64172800_64172951 0.28 Fign
 fidgetin
 74837
 0.13
chr18_54988564_54988904 0.27 Zfp608
 zinc finger protein 608
 1432
 0.35
chr13_46420548_46420948 0.27 Rbm24
 RNA binding motif protein 24
 197
 0.96
chr5_14515030_14515887 0.27 Pclo
 piccolo (presynaptic cytomatrix protein)
 465
 0.81
chr14_57132708_57133925 0.27 Gjb6
 gap junction protein, beta 6
 35
 0.97
chr2_145862226_145862910 0.27 Rin2
 Ras and Rab interactor 2
 76
 0.97
chr18_38928285_38929463 0.27 Fgf1
 fibroblast growth factor 1
 283
 0.92
chr3_100804632_100805148 0.26 Vtcn1
 V-set domain containing T cell activation inhibitor 1
 20569
 0.2
chr1_38987342_38987601 0.26 Pdcl3
 phosducin-like 3
 370
 0.84
chr17_17448568_17449744 0.26 Lix1
 limb and CNS expressed 1
 336
 0.88
chr1_185193564_185193767 0.26 Rab3gap2
 RAB3 GTPase activating protein subunit 2
 10452
 0.15
chr10_85389057_85389718 0.26 Btbd11
 BTB (POZ) domain containing 11
 2560
 0.31
chr5_146921086_146921291 0.26 Gtf3a
 general transcription factor III A
 27469
 0.14
chr8_109185308_109186079 0.25 D030068K23Rik
 RIKEN cDNA D030068K23 gene
 64173
 0.13
chr2_167239298_167240893 0.25 Ptgis
 prostaglandin I2 (prostacyclin) synthase
 494
 0.75
chr2_180388160_180389480 0.25 Mir1a-1
 microRNA 1a-1
 228
 0.89
chr11_42181406_42181557 0.25 Gabra1
 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
 623
 0.84
chr4_123406736_123407057 0.25 Macf1
 microtubule-actin crosslinking factor 1
 5332
 0.18
chr4_14621039_14622190 0.25 Slc26a7
 solute carrier family 26, member 7
 55
 0.99
chr6_53817061_53817543 0.25 Gm16499
 predicted gene 16499
 1441
 0.39
chr9_52680840_52680991 0.25 Gm1715
 predicted gene 1715
 1052
 0.41
chr10_111100028_111100179 0.25 Gm48851
 predicted gene, 48851
 2768
 0.22
chr2_65846012_65846807 0.25 Csrnp3
 cysteine-serine-rich nuclear protein 3
 554
 0.79
chr14_86261599_86262221 0.25 4930529K09Rik
 RIKEN cDNA 4930529K09 gene
 15907
 0.12
chrX_7821779_7823061 0.25 Kcnd1
 potassium voltage-gated channel, Shal-related family, member 1
 113
 0.92
chr7_78569130_78569412 0.25 Ntrk3
 neurotrophic tyrosine kinase, receptor, type 3
 2620
 0.26
chr17_8388660_8390136 0.25 Gm5491
 predicted gene 5491
 4738
 0.15
chr19_37907678_37907926 0.24 Myof
 myoferlin
 1978
 0.37
chr17_67303669_67304273 0.24 Ptprm
 protein tyrosine phosphatase, receptor type, M
 50102
 0.18
chr16_89957880_89958031 0.24 Tiam1
 T cell lymphoma invasion and metastasis 1
 1848
 0.47
chr16_20692791_20694082 0.24 Fam131a
 family with sequence similarity 131, member A
 156
 0.88
chr2_160367750_160367926 0.24 Mafb
 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
 773
 0.73
chr18_73696846_73697208 0.23 Smad4
 SMAD family member 4
 6753
 0.16
chr5_21865389_21865953 0.23 Slc26a5
 solute carrier family 26, member 5
 67
 0.96
chr14_78678524_78678680 0.23 Gm18368
 predicted gene, 18368
 25208
 0.16
chr4_91376198_91376448 0.23 Elavl2
 ELAV like RNA binding protein 1
 16
 0.98
chr18_64889550_64889704 0.23 Nedd4l
 neural precursor cell expressed, developmentally down-regulated gene 4-like
 598
 0.62
chr2_59438620_59439113 0.23 Gm13549
 predicted gene 13549
 39085
 0.13
chr14_84437974_84438125 0.23 Pcdh17
 protocadherin 17
 5514
 0.26
chr9_120098696_120098847 0.23 Gm47050
 predicted gene, 47050
 3108
 0.11
chr19_46643484_46643643 0.23 Wbp1l
 WW domain binding protein 1 like
 20162
 0.11
chr3_31026652_31026803 0.23 Prkci
 protein kinase C, iota
 4995
 0.18
chr9_78504198_78504349 0.23 Eef1a1
 eukaryotic translation elongation factor 1 alpha 1
 15122
 0.11
chr18_65393136_65393441 0.23 Alpk2
 alpha-kinase 2
 606
 0.6
chr15_44752328_44752563 0.23 Sybu
 syntabulin (syntaxin-interacting)
 13
 0.67
chr13_98534689_98535089 0.23 Gm37425
 predicted gene, 37425
 16951
 0.12
chr9_4794566_4795419 0.22 Gria4
 glutamate receptor, ionotropic, AMPA4 (alpha 4)
 527
 0.88
chr9_117870768_117871285 0.22 Rbms3
 RNA binding motif, single stranded interacting protein
 1558
 0.39
chr10_71127422_71127648 0.22 Bicc1
 BicC family RNA binding protein 1
 19325
 0.12
chr17_64346137_64346566 0.22 Pja2
 praja ring finger ubiquitin ligase 2
 14435
 0.23
chr4_53442042_53442694 0.22 Slc44a1
 solute carrier family 44, member 1
 1684
 0.42
chr19_25343674_25344266 0.22 Gm34432
 predicted gene, 34432
 3233
 0.31
chr14_91896039_91896190 0.22 Gm48943
 predicted gene, 48943
 219666
 0.02
chr18_69563797_69564227 0.22 Tcf4
 transcription factor 4
 677
 0.76
chr4_117913262_117913510 0.22 Ipo13
 importin 13
 1613
 0.23
chr12_72285979_72286146 0.22 Rtn1
 reticulon 1
 49338
 0.15
chr19_28165559_28166176 0.22 Gm35781
 predicted gene, 35781
 19564
 0.23
chr2_60036508_60037747 0.22 Gm13572
 predicted gene 13572
 14
 0.98
chr1_189910816_189911265 0.22 Gm38245
 predicted gene, 38245
 4919
 0.19
chr4_47609604_47609755 0.22 Sec61b
 Sec61 beta subunit
 134731
 0.05
chr14_31662695_31662846 0.22 Hacl1
 2-hydroxyacyl-CoA lyase 1
 21484
 0.13
chr10_102515341_102515492 0.21 Rassf9
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
 3160
 0.25
chr5_83352776_83353067 0.21 Tecrl
 trans-2,3-enoyl-CoA reductase-like
 2035
 0.43
chr6_54539408_54539559 0.21 Scrn1
 secernin 1
 14963
 0.17
chr1_163301248_163301399 0.21 Gm37644
 predicted gene, 37644
 7744
 0.18
chr10_60800688_60800996 0.21 Gm19972
 predicted gene, 19972
 13481
 0.18
chr17_17910234_17910768 0.21 Gm7535
 predicted gene 7535
 2315
 0.16
chr8_22508392_22509319 0.21 Slc20a2
 solute carrier family 20, member 2
 2629
 0.22
chr2_64074730_64075670 0.21 Fign
 fidgetin
 22788
 0.29
chr3_102224536_102224803 0.21 Vangl1
 VANGL planar cell polarity 1
 19976
 0.13
chr2_112591399_112591550 0.21 Gm44374
 predicted gene, 44374
 22556
 0.16
chr12_117163848_117163999 0.21 Gm10421
 predicted gene 10421
 12272
 0.28
chr13_32008957_32009151 0.21 Gm35732
 predicted gene, 35732
 37968
 0.18
chr2_63454866_63455043 0.21 Gm23503
 predicted gene, 23503
 22760
 0.24
chr8_66700179_66700330 0.21 Npy1r
 neuropeptide Y receptor Y1
 2832
 0.28
chr10_112270073_112271254 0.21 Kcnc2
 potassium voltage gated channel, Shaw-related subfamily, member 2
 458
 0.85
chr9_44877057_44877237 0.21 Gm39326
 predicted gene, 39326
 744
 0.44
chr9_66004589_66004841 0.21 Csnk1g1
 casein kinase 1, gamma 1
 3025
 0.23
chr11_96297868_96298678 0.20 Hoxb6
 homeobox B6
 898
 0.3
chr9_45370028_45371246 0.20 Fxyd6
 FXYD domain-containing ion transport regulator 6
 195
 0.91
chr6_8952771_8953600 0.20 Nxph1
 neurexophilin 1
 3509
 0.38
chr19_14591939_14592995 0.20 Tle4
 transducin-like enhancer of split 4
 3072
 0.36
chr2_6868272_6868550 0.20 Celf2
 CUGBP, Elav-like family member 2
 3561
 0.25
chr15_85676712_85677176 0.20 Lncppara
 long noncoding RNA near Ppara
 23328
 0.12
chr6_51844040_51844803 0.20 Skap2
 src family associated phosphoprotein 2
 27508
 0.2
chr10_120721676_120722691 0.20 Gm37505
 predicted gene, 37505
 9632
 0.13
chr2_10008087_10008238 0.20 C630004M23Rik
 RIKEN cDNA C630004M23 gene
 39676
 0.09
chr14_49176028_49176179 0.20 Naa30
 N(alpha)-acetyltransferase 30, NatC catalytic subunit
 1796
 0.31
chr17_44623731_44624125 0.20 n-R5s27
 nuclear encoded rRNA 5S 27
 17215
 0.22
chr8_121730928_121732115 0.20 Jph3
 junctophilin 3
 954
 0.49
chr14_64834470_64835221 0.20 Gm20111
 predicted gene, 20111
 4255
 0.18
chr3_53043747_53045351 0.20 Gm42901
 predicted gene 42901
 2794
 0.16
chr11_88619965_88620857 0.20 Msi2
 musashi RNA-binding protein 2
 30264
 0.2
chr19_36118883_36119585 0.20 Ankrd1
 ankyrin repeat domain 1 (cardiac muscle)
 676
 0.71
chr6_86032524_86032675 0.20 Add2
 adducin 2 (beta)
 3852
 0.13
chr17_22339851_22340002 0.20 Gm49951
 predicted gene, 49951
 6932
 0.15
chr18_38598277_38598596 0.20 Spry4
 sprouty RTK signaling antagonist 4
 2979
 0.2
chr17_79451074_79451933 0.19 Cdc42ep3
 CDC42 effector protein (Rho GTPase binding) 3
 96412
 0.07
chr4_5645693_5646152 0.19 Fam110b
 family with sequence similarity 110, member B
 1687
 0.36
chr2_137356841_137357676 0.19 Gm14055
 predicted gene 14055
 68755
 0.13
chr2_9869939_9870090 0.19 Gata3
 GATA binding protein 3
 3658
 0.15
chr3_87767082_87768667 0.19 Pear1
 platelet endothelial aggregation receptor 1
 1061
 0.43
chr16_72905751_72905902 0.19 Robo1
 roundabout guidance receptor 1
 70523
 0.14
chrX_51678767_51679193 0.19 Hs6st2
 heparan sulfate 6-O-sulfotransferase 2
 1585
 0.48
chr16_46493311_46493865 0.19 Nectin3
 nectin cell adhesion molecule 3
 3184
 0.34
chr4_25796073_25796399 0.19 Fut9
 fucosyltransferase 9
 3619
 0.24
chr14_110753127_110753447 0.19 Slitrk6
 SLIT and NTRK-like family, member 6
 1862
 0.32
chr7_54835204_54836499 0.19 Luzp2
 leucine zipper protein 2
 236
 0.94
chr7_122044795_122044946 0.19 Ears2
 glutamyl-tRNA synthetase 2, mitochondrial
 22141
 0.1
chrX_159259045_159259196 0.19 Rps6ka3
 ribosomal protein S6 kinase polypeptide 3
 2994
 0.34
chr5_25098295_25098663 0.19 Prkag2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 2163
 0.24
chr4_46202294_46203178 0.19 Xpa
 xeroderma pigmentosum, complementation group A
 6425
 0.17
chr8_84770692_84772567 0.19 Nfix
 nuclear factor I/X
 1767
 0.22
chr6_138365294_138365445 0.19 Lmo3
 LIM domain only 3
 56083
 0.13
chr5_75247144_75247638 0.19 Gm42799
 predicted gene 42799
 948
 0.57
chr3_79576778_79577000 0.19 Gm35067
 predicted gene, 35067
 5699
 0.12
chr17_22360731_22361353 0.19 Zfp944
 zinc finger protein 944
 358
 0.51
chr18_41860653_41861741 0.19 Gm50410
 predicted gene, 50410
 13637
 0.22
chr9_76014472_76015728 0.18 Hmgcll1
 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1
 45
 0.55
chr1_83517764_83517915 0.18 Gm37989
 predicted gene, 37989
 90441
 0.08
chr4_23829464_23829682 0.18 Gm28448
 predicted gene 28448
 104381
 0.08
chr10_24312237_24312511 0.18 Moxd1
 monooxygenase, DBH-like 1
 88829
 0.07
chr9_101401666_101401952 0.18 Gm24638
 predicted gene, 24638
 8699
 0.18
chr19_36115709_36115956 0.18 Ankrd1
 ankyrin repeat domain 1 (cardiac muscle)
 4078
 0.23
chr6_92532985_92533460 0.18 Prickle2
 prickle planar cell polarity protein 2
 1639
 0.46
chr6_116056244_116057282 0.18 Tmcc1
 transmembrane and coiled coil domains 1
 192
 0.94
chr6_48626698_48627876 0.18 AI854703
 expressed sequence AI854703
 6
 0.93
chr18_54984578_54984982 0.18 Zfp608
 zinc finger protein 608
 5386
 0.22
chr9_45404342_45404493 0.18 Fxyd2
 FXYD domain-containing ion transport regulator 2
 441
 0.75
chr14_79450824_79451101 0.18 Kbtbd6
 kelch repeat and BTB (POZ) domain containing 6
 873
 0.51
chr2_74694827_74695683 0.18 Gm14396
 predicted gene 14396
 265
 0.7
chr13_59431296_59431956 0.18 4930455M05Rik
 RIKEN cDNA 4930455M05 gene
 12229
 0.14
chr11_81148614_81148842 0.18 Asic2
 acid-sensing (proton-gated) ion channel 2
 4593
 0.3
chr6_128596921_128597883 0.18 Gm44009
 predicted gene, 44009
 9377
 0.09
chr6_32584464_32585789 0.18 Plxna4
 plexin A4
 3066
 0.3
chr1_23490467_23490664 0.17 Gm7784
 predicted gene 7784
 11026
 0.24
chr8_50120264_50120415 0.17 Gm45323
 predicted gene 45323
 106955
 0.07

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxo3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.2 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.6 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.2 GO:0015755 fructose transport(GO:0015755)
0.1 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.2 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.2 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0035564 regulation of kidney size(GO:0035564)
0.0 0.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.1 GO:0061110 dense core granule biogenesis(GO:0061110)
0.0 0.0 GO:1900451 positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.1 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.0 0.1 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.1 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0060618 nipple development(GO:0060618)
0.0 0.2 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:2000392 regulation of lamellipodium morphogenesis(GO:2000392) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0042160 lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.0 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0003133 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0 0.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.0 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0072262 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.2 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.0 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.0 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.0 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.0 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.0 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.0 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.0 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.1 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.0 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:1903286 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 0.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.0 GO:0060931 sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.0 GO:1904526 regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0035907 dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:1903887 motile primary cilium assembly(GO:1903887)
0.0 0.0 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0060482 lobar bronchus development(GO:0060482)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.0 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.0 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.0 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:0060112 generation of ovulation cycle rhythm(GO:0060112)
0.0 0.0 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026)
0.0 0.0 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.0 0.0 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.0 GO:0090032 negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0 0.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0070671 response to interleukin-12(GO:0070671)
0.0 0.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0009445 putrescine metabolic process(GO:0009445)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.0 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.4 GO:0097001 ceramide binding(GO:0097001)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0034824 enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0 0.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0008251 tRNA-specific adenosine deaminase activity(GO:0008251)
0.0 0.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.0 GO:0038064 collagen receptor activity(GO:0038064)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0004118 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME CELL CELL COMMUNICATION Genes involved in Cell-Cell communication
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins