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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Gzf1

Z-value: 0.33

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Transcription factors associated with Gzf1

Gene Symbol	Gene ID	Gene Info
Gzf1 Ensembl NCBI MGI UniProt	ENSMUSG00000027439.9	Gzf1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Gzf1	chr2_148680576_148680950	260	0.897015	0.38	2.6e-03	Click!
Gzf1	chr2_148678935_148679497	1807	0.288201	-0.33	9.9e-03	Click!
Gzf1	chr2_148678060_148678476	2755	0.213132	-0.27	3.8e-02	Click!
Gzf1	chr2_148682624_148682775	1488	0.339850	0.14	2.9e-01	Click!
Gzf1	chr2_148677237_148678042	3384	0.190726	-0.07	5.8e-01	Click!

Activity of the Gzf1 motif across conditions

Conditions sorted by the z-value of the Gzf1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_80258361_80258974	1.18	Slc66a2	solute carrier family 66 member 2	2349	0.18
chr1_9776842_9777028	0.72	1700034P13Rik	RIKEN cDNA 1700034P13 gene	6843	0.14
chr17_25089311_25089630	0.62	Ift140	intraflagellar transport 140	1201	0.31
chr1_40430303_40430529	0.61	Il1rl1	interleukin 1 receptor-like 1	846	0.63
chr9_43234131_43234830	0.54	Oaf	out at first homolog	5431	0.16
chr15_75906413_75907979	0.51	Eef1d	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	1833	0.15
chr12_111445027_111446639	0.51	Tnfaip2	tumor necrosis factor, alpha-induced protein 2	251	0.87
chr4_132396755_132396912	0.47	Phactr4	phosphatase and actin regulator 4	1366	0.24
chr16_91466045_91466196	0.45	Gm49626	predicted gene, 49626	995	0.24
chr19_60871718_60871869	0.44	Prdx3	peroxiredoxin 3	2763	0.19
chr8_13108983_13109168	0.43	Cul4a	cullin 4A	3139	0.13
chr2_109281814_109282372	0.43	Kif18a	kinesin family member 18A	1224	0.4
chr3_127931525_127931952	0.43	9830132P13Rik	RIKEN cDNA 9830132P13 gene	15566	0.14
chr3_4796861_4798079	0.42	1110015O18Rik	RIKEN cDNA 1110015O18 gene	88	0.98
chr11_95012524_95013312	0.42	Samd14	sterile alpha motif domain containing 14	2637	0.16
chr15_80081033_80081744	0.41	Rpl3	ribosomal protein L3	907	0.27
chr11_103102696_103105788	0.39	Acbd4	acyl-Coenzyme A binding domain containing 4	463	0.7
chr2_155990244_155990644	0.38	Cep250	centrosomal protein 250	4529	0.12
chr6_87765679_87766248	0.35	Gm5879	predicted gene 5879	241	0.82
chr2_26576901_26577217	0.34	Egfl7	EGF-like domain 7	2955	0.12
chr2_30185302_30185471	0.34	Spout1	SPOUT domain containing methyltransferase 1	6927	0.1
chr13_115529338_115529813	0.33	Gm6035	predicted gene 6035	197	0.97
chr12_17539903_17540224	0.33	Odc1	ornithine decarboxylase, structural 1	4731	0.16
chr1_97656733_97656884	0.32	AC099860.1	proline rich protein BstNI subfamily 4 (PRB4), pseudogene	4023	0.23
chr15_45112888_45113052	0.32	Kcnv1	potassium channel, subfamily V, member 1	1857	0.43
chr4_154024246_154024397	0.32	Smim1	small integral membrane protein 1	2	0.95
chr19_55125788_55126185	0.31	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	1217	0.49
chr13_37826269_37827832	0.31	Rreb1	ras responsive element binding protein 1	118	0.96
chr9_95554372_95554523	0.31	Gm32281	predicted gene, 32281	50	0.96
chr4_112955735_112956277	0.31	Gm12816	predicted gene 12816	280	0.92
chr13_98810152_98810868	0.30	Fcho2	FCH domain only 2	4643	0.14
chr18_21283979_21284139	0.30	Garem1	GRB2 associated regulator of MAPK1 subtype 1	16064	0.17
chr9_66182641_66182896	0.30	Dapk2	death-associated protein kinase 2	24533	0.17
chrX_13202535_13203215	0.29	Rpl3-ps1	ribosomal protein L3, pseudogene 1	304	0.82
chr5_150642312_150642463	0.29	N4bp2l2	NEDD4 binding protein 2-like 2	5132	0.13
chr15_76666348_76670076	0.29	Foxh1	forkhead box H1	1590	0.15
chr12_95693703_95697493	0.28	Flrt2	fibronectin leucine rich transmembrane protein 2	241	0.92
chr11_69945712_69946013	0.28	Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	2112	0.1
chr16_56036340_56036491	0.27	Gm22422	predicted gene, 22422	528	0.58
chr15_80098310_80099146	0.27	Syngr1	synaptogyrin 1	858	0.41
chr15_36606762_36607275	0.26	Pabpc1	poly(A) binding protein, cytoplasmic 1	1552	0.29
chr1_131274859_131275440	0.26	Ikbke	inhibitor of kappaB kinase epsilon	1564	0.27
chr12_111833317_111833616	0.25	Zfyve21	zinc finger, FYVE domain containing 21	8701	0.11
chr8_94174521_94174806	0.25	Gm45774	predicted gene 45774	1251	0.25
chrX_140956935_140957373	0.25	Atg4a	autophagy related 4A, cysteine peptidase	204	0.73
chr9_103228079_103228881	0.24	Trf	transferrin	38	0.97
chr11_84701121_84702313	0.24	1700109G15Rik	RIKEN cDNA 1700109G15 gene	18715	0.2
chr4_155847422_155848255	0.24	Dvl1	dishevelled segment polarity protein 1	167	0.85
chr13_23695605_23696868	0.23	H1f6	H1.6 linker histone, cluster member	422	0.53
chr5_67845808_67845959	0.23	Gm15477	predicted gene 15477	1182	0.26
chr1_178321962_178322153	0.23	Hnrnpu	heterogeneous nuclear ribonucleoprotein U	2114	0.17
chr8_13038721_13039033	0.22	F10	coagulation factor X	1039	0.34
chr6_54008580_54009014	0.21	4921529L05Rik	RIKEN cDNA 4921529L05 gene	915	0.6
chr6_119009028_119009204	0.21	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	70891	0.12
chr4_123286782_123287699	0.21	Gm25788	predicted gene, 25788	4104	0.11
chr17_31057450_31058949	0.21	Abcg1	ATP binding cassette subfamily G member 1	425	0.72
chr6_8208939_8210019	0.20	Mios	meiosis regulator for oocyte development	257	0.91
chr2_181081653_181082036	0.20	Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	13577	0.13
chr7_120176025_120176210	0.20	Anks4b	ankyrin repeat and sterile alpha motif domain containing 4B	2259	0.22
chr4_118080461_118080612	0.20	St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	48654	0.11
chr19_45779130_45779398	0.20	Oga	O-GlcNAcase	4287	0.16
chr9_113915715_113915866	0.19	Ubp1	upstream binding protein 1	15144	0.21
chr1_90216532_90216683	0.19	Gm38277	predicted gene, 38277	11919	0.16
chr2_57613916_57615034	0.19	Gm13532	predicted gene 13532	14753	0.2
chr8_109250241_109250821	0.19	D030068K23Rik	RIKEN cDNA D030068K23 gene	665	0.8
chr12_86881882_86884741	0.19	Irf2bpl	interferon regulatory factor 2 binding protein-like	1487	0.4
chr15_61365878_61366029	0.19	Gm24696	predicted gene, 24696	7949	0.28
chr4_59233833_59234326	0.19	Ugcg	UDP-glucose ceramide glucosyltransferase	21423	0.16
chr3_89458801_89459905	0.19	Pmvk	phosphomevalonate kinase	22	0.95
chr12_55303747_55303898	0.18	Prorp	protein only RNase P catalytic subunit	536	0.54
chr19_9896568_9896747	0.18	Incenp	inner centromere protein	1197	0.24
chr2_79268859_79269010	0.18	Itga4	integrin alpha 4	12987	0.22
chr15_83366703_83367634	0.18	1700001L05Rik	RIKEN cDNA 1700001L05 gene	109	0.96
chr3_40745266_40746433	0.18	Hspa4l	heat shock protein 4 like	19	0.97
chr1_24349529_24350209	0.18	Col19a1	collagen, type XIX, alpha 1	102876	0.06
chr2_93456061_93456647	0.17	Gm10804	predicted gene 10804	3533	0.2
chr5_122291128_122291986	0.17	Pptc7	PTC7 protein phosphatase homolog	4215	0.13
chr6_22878521_22878977	0.16	Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1	2972	0.31
chr5_36733334_36733545	0.16	Gm43701	predicted gene 43701	15179	0.12
chr11_85132321_85132613	0.16	Usp32	ubiquitin specific peptidase 32	7462	0.14
chr8_105855169_105856239	0.15	Thap11	THAP domain containing 11	572	0.5
chr13_64149393_64149567	0.15	Zfp367	zinc finger protein 367	734	0.52
chr16_52303393_52303591	0.15	Alcam	activated leukocyte cell adhesion molecule	6568	0.33
chr15_74516560_74519631	0.15	Adgrb1	adhesion G protein-coupled receptor B1	1264	0.47
chr15_85677376_85679232	0.15	Lncppara	long noncoding RNA near Ppara	24688	0.12
chr15_27994630_27995403	0.15	Trio	triple functional domain (PTPRF interacting)	347	0.9
chr3_152198770_152199020	0.15	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	5050	0.14
chr10_80141919_80142171	0.15	Atp5d	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	270	0.76
chr17_46817734_46818115	0.14	Bicral	BRD4 interacting chromatin remodeling complex associated protein like	5739	0.14
chr8_35596914_35597077	0.14	Gm16793	predicted gene, 16793	8023	0.19
chr4_148149332_148150056	0.14	Fbxo6	F-box protein 6	25	0.95
chr9_94538014_94538635	0.14	Dipk2a	divergent protein kinase domain 2A	243	0.94
chr7_144132849_144134003	0.14	Gm44999	predicted gene 44999	22341	0.2
chr4_145245818_145247120	0.14	Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	401	0.87
chr17_29660688_29661601	0.14	Cmtr1	cap methyltransferase 1	337	0.79
chr9_21836571_21836722	0.14	Angptl8	angiopoietin-like 8	1136	0.32
chr9_71163629_71163837	0.14	Gm32511	predicted gene, 32511	61	0.87
chr6_120914700_120915049	0.14	Gm44260	predicted gene, 44260	119	0.93
chr10_111249619_111250191	0.13	Osbpl8	oxysterol binding protein-like 8	1837	0.35
chr1_91252025_91252209	0.13	Ube2f	ubiquitin-conjugating enzyme E2F (putative)	1461	0.34
chr17_33715168_33715319	0.13	Marchf2	membrane associated ring-CH-type finger 2	1862	0.19
chr2_117440042_117440467	0.13	Gm13982	predicted gene 13982	22557	0.24
chr18_67563907_67564259	0.13	Gm17669	predicted gene, 17669	1689	0.34
chr11_102894553_102894704	0.13	Gfap	glial fibrillary acidic protein	2503	0.15
chr10_127643084_127644231	0.12	Stat6	signal transducer and activator of transcription 6	655	0.49
chr10_59800628_59800855	0.12	Gm17059	predicted gene 17059	487	0.74
chr4_117121385_117121536	0.12	Btbd19	BTB (POZ) domain containing 19	195	0.83
chr14_31020004_31020155	0.12	Pbrm1	polybromo 1	871	0.28
chr17_57246789_57247636	0.12	Gpr108	G protein-coupled receptor 108	451	0.69
chr15_82792748_82793304	0.12	Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	1196	0.3
chr2_77515617_77516160	0.12	Zfp385b	zinc finger protein 385B	3647	0.32
chr15_102516242_102517900	0.12	Map3k12	mitogen-activated protein kinase kinase kinase 12	7	0.93
chr8_10928168_10928319	0.12	3930402G23Rik	RIKEN cDNA 3930402G23 gene	201	0.87
chr13_9095816_9096692	0.12	Larp4b	La ribonucleoprotein domain family, member 4B	2272	0.25
chr12_40842378_40842529	0.11	Gm19441	predicted gene, 19441	33084	0.14
chr13_36613015_36613742	0.11	Gm46409	predicted gene, 46409	406	0.82
chr14_118768312_118768652	0.11	Gm22379	predicted gene, 22379	6670	0.17
chr2_92458690_92458841	0.11	Slc35c1	solute carrier family 35, member C1	944	0.45
chr5_124094995_124096382	0.11	Abcb9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	98	0.94
chr2_164912255_164912427	0.11	Zfp335	zinc finger protein 335	584	0.5
chr11_29527773_29527935	0.11	Mtif2	mitochondrial translational initiation factor 2	1397	0.27
chr4_134982769_134983159	0.11	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	51954	0.11
chr2_120404274_120404845	0.11	Ganc	glucosidase, alpha; neutral C	209	0.72
chr15_79691713_79691926	0.11	n-R5s40	nuclear encoded rRNA 5S 40	683	0.38
chr2_162931631_162931821	0.11	Srsf6	serine and arginine-rich splicing factor 6	65	0.96
chr16_20619702_20620440	0.11	Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2	1216	0.19
chr12_102757998_102758734	0.11	Gm20604	predicted gene 20604	306	0.39
chr4_46720937_46721311	0.11	Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	3267	0.31
chr13_51649766_51650138	0.11	Secisbp2	SECIS binding protein 2	1745	0.26
chr11_83227446_83227655	0.10	Gm11427	predicted gene 11427	3064	0.12
chr2_18056806_18058206	0.10	Mir7655	microRNA 7655	340	0.69
chrY_90828377_90829257	0.10	Gm21742	predicted gene, 21742	8596	0.19
chr15_95702325_95702476	0.10	Gm8843	predicted gene 8843	12793	0.16
chr7_60960862_60961355	0.10	Gm44643	predicted gene 44643	277	0.94
chr3_30407909_30408060	0.10	Gm37024	predicted gene, 37024	80442	0.07
chr7_25176596_25177413	0.10	Pou2f2	POU domain, class 2, transcription factor 2	2722	0.15
chr19_57357866_57358369	0.10	Fam160b1	family with sequence similarity 160, member B1	2563	0.21
chr4_137927893_137928360	0.10	Ece1	endothelin converting enzyme 1	14444	0.2
chr8_94874074_94874812	0.10	Dok4	docking protein 4	1653	0.23
chr1_69759441_69760065	0.10	Gm37930	predicted gene, 37930	11115	0.24
chr19_46396930_46398133	0.10	Sufu	SUFU negative regulator of hedgehog signaling	505	0.64
chr7_61980139_61980379	0.10	A330076H08Rik	RIKEN cDNA A330076H08 gene	2044	0.2
chr11_101936838_101937005	0.10	Rpl27-ps2	ribosomal protein L27, pseudogene 2	2580	0.16
chr1_173366699_173367980	0.09	Cadm3	cell adhesion molecule 3	294	0.89
chr11_97745312_97745500	0.09	Mir8102	microRNA 8102	509	0.43
chr3_145923629_145924032	0.09	Bcl10	B cell leukemia/lymphoma 10	432	0.82
chr15_82243863_82244385	0.09	Cenpm	centromere protein M	208	0.85
chr4_133016211_133017810	0.09	Ahdc1	AT hook, DNA binding motif, containing 1	4806	0.2
chr10_84917701_84918233	0.09	Ric8b	RIC8 guanine nucleotide exchange factor B	311	0.93
chr8_94035053_94035555	0.09	Nudt21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	1702	0.22
chr1_64731523_64731946	0.09	Gm38058	predicted gene, 38058	4506	0.18
chr11_77800451_77802048	0.09	Myo18a	myosin XVIIIA	49	0.97
chr4_100123667_100123818	0.09	Gm12701	predicted gene 12701	4121	0.26
chr18_76469370_76469521	0.09	Gm50360	predicted gene, 50360	147621	0.04
chr2_25290133_25293095	0.09	Grin1os	glutamate receptor, ionotropic, NMDA1 (zeta 1), opposite strand	394	0.57
chr19_41345332_41345831	0.09	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	39515	0.17
chr11_117115216_117116282	0.09	Sec14l1	SEC14-like lipid binding 1	497	0.68
chr3_89225214_89225991	0.08	Thbs3	thrombospondin 3	425	0.52
chr2_122364330_122364498	0.08	Shf	Src homology 2 domain containing F	2414	0.2
chr13_117605053_117605376	0.08	Hcn1	hyperpolarization activated cyclic nucleotide gated potassium channel 1	2734	0.39
chr2_73910369_73911256	0.08	Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	353	0.88
chr15_58933816_58934225	0.08	Ndufb9	NADH:ubiquinone oxidoreductase subunit B9	212	0.57
chr8_76898913_76900466	0.08	Nr3c2	nuclear receptor subfamily 3, group C, member 2	83	0.77
chr7_19562594_19562787	0.08	Ppp1r37	protein phosphatase 1, regulatory subunit 37	386	0.71
chr16_36453993_36454231	0.08	Stfa3	stefin A3	1280	0.27
chr11_84592794_84593319	0.08	Lhx1os	LIM homeobox 1, opposite strand	67372	0.1
chr5_38503165_38503316	0.08	Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	97	0.96
chr7_29308550_29309973	0.08	Dpf1	D4, zinc and double PHD fingers family 1	252	0.86
chr6_83325542_83325912	0.08	Mthfd2	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase	181	0.62
chr13_81783279_81784146	0.07	Gm17259	predicted gene, 17259	37	0.6
chr14_12191443_12191651	0.07	Ptprg	protein tyrosine phosphatase, receptor type, G	1604	0.41
chrX_162017252_162017925	0.07	Gm26317	predicted gene, 26317	51869	0.15
chr8_25753750_25754361	0.07	Ddhd2	DDHD domain containing 2	225	0.66
chr16_35810940_35811264	0.07	Gm26838	predicted gene, 26838	2156	0.22
chr15_76713644_76714446	0.07	Lrrc14	leucine rich repeat containing 14	3314	0.09
chr14_121359067_121359218	0.07	Stk24	serine/threonine kinase 24	726	0.7
chr7_130367477_130367756	0.07	Gm5903	predicted gene 5903	13254	0.22
chr11_101277950_101278906	0.07	Coa3	cytochrome C oxidase assembly factor 3	515	0.36
chr11_93103184_93103429	0.07	Car10	carbonic anhydrase 10	4016	0.37
chr19_8710109_8710483	0.07	Slc3a2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	2689	0.07
chr8_117261523_117261917	0.07	Cmip	c-Maf inducing protein	4603	0.29
chr5_124048455_124048606	0.07	Gm43661	predicted gene 43661	3822	0.12
chr10_69351583_69352885	0.07	Cdk1	cyclin-dependent kinase 1	669	0.68
chr18_60927346_60927498	0.07	Camk2a	calcium/calmodulin-dependent protein kinase II alpha	473	0.75
chr1_72710929_72711175	0.07	Rpl37a	ribosomal protein L37a	238	0.9
chr4_117891166_117892323	0.07	Dph2	DPH2 homolog	242	0.84
chr2_167337310_167337492	0.07	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	11782	0.18
chr1_81133034_81133185	0.07	Nyap2	neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2	55526	0.17
chr10_79681285_79681959	0.07	Cdc34	cell division cycle 34	573	0.51
chr9_88520550_88520755	0.06	Snord50a	small nucleolar RNA, C/D box 50A	948	0.28
chr16_96122312_96122501	0.06	Hmgn1	high mobility group nucleosomal binding domain 1	2933	0.17
chr18_9449055_9449747	0.06	Ccny	cyclin Y	285	0.9
chr16_3907313_3907961	0.06	1700037C18Rik	RIKEN cDNA 1700037C18 gene	14	0.91
chr7_46639032_46639734	0.06	Sergef	secretion regulating guanine nucleotide exchange factor	197	0.91
chr11_115698285_115698728	0.06	Grb2	growth factor receptor bound protein 2	801	0.46
chr19_41906848_41907300	0.06	Gm46644	predicted gene, 46644	4185	0.12
chr1_66386919_66387899	0.06	Map2	microtubule-associated protein 2	398	0.87
chr17_46282048_46282988	0.06	Tjap1	tight junction associated protein 1	138	0.92
chr7_107594370_107595799	0.06	Ppfibp2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	123	0.95
chr17_17294036_17294239	0.06	Gm6712	predicted gene 6712	306	0.9

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Gzf1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	0.4	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
0.1	0.3	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1	0.2	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1	0.2	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.2	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.1	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.2	GO:0051697	protein delipidation(GO:0051697)
0.0	0.2	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.4	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.2	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.0	0.1	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:1904587	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.1	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0	0.1	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.1	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.0	0.1	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.1	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.0	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.0	GO:0071351	cellular response to interleukin-18(GO:0071351)
0.0	0.0	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.0	GO:1903238	positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0	0.2	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.2	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.0	GO:0002484	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.0	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0097433	dense body(GO:0097433)
0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4	GO:0000145	exocyst(GO:0000145)
0.2	GO:0061700	GATOR2 complex(GO:0061700)
0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	GO:0072534	perineuronal net(GO:0072534)
0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling