Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Hivep1

Z-value: 0.60

Motif logo

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Transcription factors associated with Hivep1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021366.7 Hivep1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Hivep1chr13_42102879_42104009510400.1417710.445.0e-04Click!
Hivep1chr13_42093838_42093989415090.1617170.264.6e-02Click!
Hivep1chr13_42193094_4219329089280.2720950.229.5e-02Click!
Hivep1chr13_42108593_42108844484160.150451-0.201.3e-01Click!
Hivep1chr13_42051086_420517576000.7322980.152.5e-01Click!

Activity of the Hivep1 motif across conditions

Conditions sorted by the z-value of the Hivep1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_7421074_7423945 1.33 Mir6991
microRNA 6991
64
0.94
chr19_44406059_44406210 1.13 Scd1
stearoyl-Coenzyme A desaturase 1
556
0.7
chr15_25416360_25416622 1.02 Gm48957
predicted gene, 48957
1428
0.31
chr7_100465236_100467118 0.81 C2cd3
C2 calcium-dependent domain containing 3
770
0.37
chr9_95560936_95561583 0.68 Paqr9
progestin and adipoQ receptor family member IX
1602
0.28
chr2_152081612_152083149 0.67 Scrt2
scratch family zinc finger 2
851
0.52
chr5_97222612_97223731 0.67 Gm2861
predicted gene 2861
27585
0.16
chr6_125361206_125362192 0.64 Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
1272
0.34
chr1_23380807_23381185 0.61 Ogfrl1
opioid growth factor receptor-like 1
195
0.95
chr6_31614524_31614772 0.60 Gm43154
predicted gene 43154
9359
0.19
chr15_66239150_66239501 0.60 Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
46726
0.14
chr3_17791475_17791708 0.60 Mir124-2hg
Mir124-2 host gene (non-protein coding)
1634
0.35
chr7_51621596_51622924 0.59 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
39
0.98
chr3_17790851_17791260 0.59 Mir124-2hg
Mir124-2 host gene (non-protein coding)
1098
0.49
chr2_27027194_27027995 0.58 Slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
315
0.79
chr2_167054833_167055386 0.57 Znfx1
zinc finger, NFX1-type containing 1
5316
0.1
chr2_165471993_165472731 0.57 Slc13a3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
837
0.54
chr1_21243770_21243921 0.57 Gsta3
glutathione S-transferase, alpha 3
3216
0.15
chr8_106336310_106337932 0.56 Smpd3
sphingomyelin phosphodiesterase 3, neutral
867
0.61
chr1_171225202_171226411 0.55 Apoa2
apolipoprotein A-II
715
0.4
chr9_44400740_44400898 0.51 Mir7085
microRNA 7085
396
0.53
chr11_119671153_119671590 0.50 Rptor
regulatory associated protein of MTOR, complex 1
15427
0.17
chr18_60925301_60926809 0.50 Camk2a
calcium/calmodulin-dependent protein kinase II alpha
330
0.84
chr1_74154867_74155069 0.50 Cxcr2
chemokine (C-X-C motif) receptor 2
977
0.45
chr16_91229951_91230102 0.49 Olig2
oligodendrocyte transcription factor 2
4569
0.14
chr8_122292467_122292618 0.49 Zfpm1
zinc finger protein, multitype 1
10401
0.15
chr5_146686924_146687505 0.48 4930573C15Rik
RIKEN cDNA 4930573C15 gene
19408
0.16
chr15_73747800_73749334 0.48 Ptp4a3
protein tyrosine phosphatase 4a3
193
0.94
chr7_101421730_101422385 0.47 Pde2a
phosphodiesterase 2A, cGMP-stimulated
211
0.91
chr2_70564530_70567543 0.47 Gad1
glutamate decarboxylase 1
341
0.83
chr2_143546820_143547517 0.46 Pcsk2os1
proprotein convertase subtilisin/kexin type 2, opposite strand 1
669
0.53
chr14_67236008_67239452 0.46 Ebf2
early B cell factor 2
3086
0.21
chr11_96328165_96328613 0.46 Hoxb3
homeobox B3
327
0.72
chr11_75436536_75436866 0.46 Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
2199
0.14
chr7_142088584_142090929 0.45 Dusp8
dual specificity phosphatase 8
5516
0.09
chr7_99383478_99385192 0.44 Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
1563
0.33
chr9_65577421_65577761 0.44 Plekho2
pleckstrin homology domain containing, family O member 2
491
0.74
chr2_158606690_158608449 0.44 Gm14204
predicted gene 14204
3021
0.15
chr11_102372614_102373077 0.43 Bloodlinc
Bloodlinc, erythroid developmental long intergenic non-protein coding transcript
4175
0.11
chr3_132015202_132015378 0.43 Gm22421
predicted gene, 22421
67102
0.11
chr15_96709976_96710732 0.42 Gm38144
predicted gene, 38144
10181
0.17
chr13_83739310_83740387 0.42 C130071C03Rik
RIKEN cDNA C130071C03 gene
985
0.29
chr6_120666289_120667501 0.42 Cecr2
CECR2, histone acetyl-lysine reader
313
0.9
chr8_87471412_87471563 0.42 Cbln1
cerebellin 1 precursor protein
419
0.7
chr14_69273653_69274347 0.42 Gm20236
predicted gene, 20236
8140
0.09
chr3_14889110_14890285 0.42 Car2
carbonic anhydrase 2
3058
0.25
chr13_46616900_46617141 0.42 Gm47523
predicted gene, 47523
2760
0.25
chr9_111022301_111022797 0.41 Ltf
lactotransferrin
133
0.92
chr14_69491925_69492597 0.41 Gm37094
predicted gene, 37094
8129
0.1
chr8_88301330_88302008 0.41 Adcy7
adenylate cyclase 7
1290
0.46
chr12_72374494_72375432 0.41 Rtn1
reticulon 1
34091
0.18
chr13_69736281_69736725 0.41 Ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
3386
0.16
chr15_82230034_82230311 0.41 Gm49503
predicted gene, 49503
3359
0.1
chr13_42093838_42093989 0.41 Hivep1
human immunodeficiency virus type I enhancer binding protein 1
41509
0.16
chr9_63148290_63148906 0.41 Skor1
SKI family transcriptional corepressor 1
363
0.86
chr8_54954519_54955779 0.40 Gpm6a
glycoprotein m6a
306
0.88
chr15_48788061_48788679 0.40 Csmd3
CUB and Sushi multiple domains 3
3563
0.34
chr19_36111787_36111969 0.39 Ankrd1
ankyrin repeat domain 1 (cardiac muscle)
8032
0.19
chr7_74006482_74006835 0.39 St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
7016
0.2
chr10_95112638_95112789 0.39 Gm48868
predicted gene, 48868
3666
0.21
chr9_91366433_91367646 0.39 Zic1
zinc finger protein of the cerebellum 1
1229
0.26
chr9_111351872_111352351 0.39 Trank1
tetratricopeptide repeat and ankyrin repeat containing 1
22709
0.17
chr5_22747292_22747672 0.39 A930003O13Rik
RIKEN cDNA A930003O13 gene
575
0.59
chr3_26329790_26330404 0.38 A830092H15Rik
RIKEN cDNA A830092H15 gene
1053
0.5
chr11_62575451_62576728 0.38 Trpv2
transient receptor potential cation channel, subfamily V, member 2
36
0.94
chr18_82567966_82568510 0.38 Mbp
myelin basic protein
4976
0.19
chr7_120879515_120880256 0.38 Eef2k
eukaryotic elongation factor-2 kinase
3665
0.15
chr7_36706015_36706419 0.38 Gm37452
predicted gene, 37452
3957
0.16
chr12_87026152_87027307 0.38 Tmem63c
transmembrane protein 63c
113
0.95
chr13_112289274_112289896 0.38 Ankrd55
ankyrin repeat domain 55
765
0.56
chr16_38092274_38092425 0.37 Gsk3b
glycogen synthase kinase 3 beta
2061
0.37
chr6_134886811_134888239 0.37 Gpr19
G protein-coupled receptor 19
243
0.87
chr14_40992016_40992401 0.37 Prxl2a
peroxiredoxin like 2A
10896
0.17
chr4_100995628_100995943 0.37 Cachd1
cache domain containing 1
1075
0.53
chr6_136938496_136939168 0.37 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
759
0.55
chr11_87756102_87757558 0.37 Mir142
microRNA 142
34
0.59
chr12_103628225_103628382 0.37 Serpina10
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
3118
0.16
chr7_98170981_98171280 0.36 Capn5
calpain 5
5689
0.15
chr3_88458101_88459325 0.36 Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
163
0.88
chr2_146414905_146415144 0.36 Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
2148
0.42
chr16_77417791_77418279 0.35 Gm38071
predicted gene, 38071
1411
0.28
chr4_138677505_138678048 0.35 Vwa5b1
von Willebrand factor A domain containing 5B1
41892
0.11
chr11_109613776_109614095 0.35 Wipi1
WD repeat domain, phosphoinositide interacting 1
1968
0.25
chr5_122643939_122644639 0.35 P2rx7
purinergic receptor P2X, ligand-gated ion channel, 7
124
0.95
chr10_86023427_86024178 0.35 A230060F14Rik
RIKEN cDNA A230060F14 gene
1473
0.24
chr17_35262769_35262981 0.35 H2-D1
histocompatibility 2, D region locus 1
145
0.85
chr2_38355912_38358148 0.35 Lhx2
LIM homeobox protein 2
3228
0.18
chr5_137569837_137570642 0.35 Tfr2
transferrin receptor 2
370
0.67
chr6_146220976_146221548 0.34 Itpr2
inositol 1,4,5-triphosphate receptor 2
6281
0.26
chr10_111250333_111250593 0.34 Osbpl8
oxysterol binding protein-like 8
2395
0.29
chr17_56466957_56467510 0.34 Ptprs
protein tyrosine phosphatase, receptor type, S
5017
0.17
chr4_9269280_9270516 0.34 Clvs1
clavesin 1
551
0.81
chr14_98957075_98957508 0.34 Gm18148
predicted gene, 18148
34637
0.13
chr7_80201202_80201353 0.34 Sema4b
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
2741
0.14
chrX_20290867_20291587 0.34 Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
543
0.77
chr9_110989233_110989717 0.34 Gm10030
predicted gene 10030
24
0.62
chr10_89453471_89453684 0.34 Gas2l3
growth arrest-specific 2 like 3
9610
0.24
chr2_93460789_93461036 0.34 Cd82
CD82 antigen
1000
0.52
chr10_60280149_60280703 0.34 Psap
prosaposin
2798
0.26
chr5_120426542_120426693 0.33 Lhx5
LIM homeobox protein 5
5082
0.14
chr1_89926124_89928011 0.33 Gbx2
gastrulation brain homeobox 2
2118
0.3
chr2_52555939_52556090 0.33 Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
695
0.69
chr17_29395290_29395481 0.32 Fgd2
FYVE, RhoGEF and PH domain containing 2
18884
0.11
chr17_50469810_50471023 0.32 Plcl2
phospholipase C-like 2
38987
0.2
chr15_39391612_39392273 0.32 Rims2
regulating synaptic membrane exocytosis 2
142
0.97
chr1_92849002_92850443 0.32 Mir149
microRNA 149
656
0.43
chr4_83284107_83285357 0.32 Ttc39b
tetratricopeptide repeat domain 39B
437
0.75
chr7_121071517_121071723 0.32 Igsf6
immunoglobulin superfamily, member 6
2952
0.12
chr10_67296874_67297090 0.32 Gm49454
predicted gene, 49454
424
0.82
chr17_30590733_30590922 0.31 Gm50244
predicted gene, 50244
681
0.53
chr9_110306106_110306257 0.31 Elp6
elongator acetyltransferase complex subunit 6
685
0.54
chr8_121901506_121902885 0.31 Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
5499
0.11
chr1_64115967_64116210 0.31 Klf7
Kruppel-like factor 7 (ubiquitous)
5394
0.21
chr2_127369985_127371247 0.30 Adra2b
adrenergic receptor, alpha 2b
7330
0.15
chr3_101828763_101828914 0.30 Mab21l3
mab-21-like 3
7385
0.23
chr15_103105344_103105529 0.30 Gm28265
predicted gene 28265
834
0.41
chr3_117577175_117577458 0.30 Plppr5
phospholipid phosphatase related 5
2089
0.46
chr8_109337659_109338724 0.30 Gm1943
predicted gene 1943
2673
0.35
chr1_132377740_132377939 0.30 Gm15849
predicted gene 15849
3290
0.17
chr5_148152589_148153094 0.30 Gm10167
predicted pseudogene 10167
31536
0.17
chr1_58964778_58965097 0.29 Trak2
trafficking protein, kinesin binding 2
8492
0.15
chr15_91752129_91752280 0.29 Lrrk2
leucine-rich repeat kinase 2
13256
0.22
chr1_23282787_23283466 0.29 Gm27028
predicted gene, 27028
8411
0.12
chr11_61653052_61653203 0.29 Grap
GRB2-related adaptor protein
138
0.96
chr15_83758810_83759041 0.29 Mpped1
metallophosphoesterase domain containing 1
20542
0.19
chr6_99694538_99694689 0.29 Gpr27
G protein-coupled receptor 27
1934
0.25
chr9_119718076_119718227 0.29 Scn10a
sodium channel, voltage-gated, type X, alpha
812
0.7
chr1_161968893_161969150 0.29 4930558K02Rik
RIKEN cDNA 4930558K02 gene
127
0.39
chr7_127660532_127660683 0.29 Gm44760
predicted gene 44760
2373
0.14
chr7_144238658_144240098 0.29 Shank2
SH3 and multiple ankyrin repeat domains 2
653
0.8
chr1_72534545_72535249 0.29 Marchf4
membrane associated ring-CH-type finger 4
2033
0.35
chr11_7198841_7199124 0.29 Igfbp1
insulin-like growth factor binding protein 1
1200
0.44
chr9_44339477_44339803 0.29 Hmbs
hydroxymethylbilane synthase
76
0.9
chr8_118286278_118286943 0.29 Cdh13
cadherin 13
2813
0.38
chr11_102264393_102264544 0.29 Hrob
homologous recombination factor with OB-fold
2504
0.14
chr2_38354292_38355594 0.28 Lhx2
LIM homeobox protein 2
1141
0.41
chr17_53587769_53587951 0.28 Kat2b
K(lysine) acetyltransferase 2B
3734
0.19
chr17_24202438_24203465 0.28 Tbc1d24
TBC1 domain family, member 24
2531
0.12
chr19_38263947_38265363 0.28 Lgi1
leucine-rich repeat LGI family, member 1
5
0.97
chr10_52742602_52743261 0.28 Gm47624
predicted gene, 47624
49093
0.11
chr9_110989935_110990508 0.28 Rtp3
receptor transporter protein 3
362
0.61
chr2_70558567_70559918 0.28 Gad1
glutamate decarboxylase 1
2800
0.19
chr10_105689563_105689778 0.28 n-R5s80
nuclear encoded rRNA 5S 80
114527
0.05
chr5_111874198_111874349 0.28 Gm42488
predicted gene 42488
69962
0.1
chr1_156986339_156986825 0.28 4930439D14Rik
RIKEN cDNA 4930439D14 gene
46744
0.11
chr4_44701489_44702654 0.28 5730488B01Rik
RIKEN cDNA 5730488B01 gene
729
0.51
chr5_148389491_148389720 0.27 Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
3210
0.3
chr2_70557968_70558533 0.27 Gad1
glutamate decarboxylase 1
3792
0.17
chr17_86379664_86379984 0.27 2010106C02Rik
RIKEN cDNA 2010106C02 gene
92646
0.08
chr15_85566918_85567069 0.27 Wnt7b
wingless-type MMTV integration site family, member 7B
29
0.97
chr3_68499533_68499761 0.27 Schip1
schwannomin interacting protein 1
5439
0.26
chr12_88723574_88724074 0.27 Nrxn3
neurexin III
715
0.73
chr15_102461035_102461435 0.27 Prr13
proline rich 13
1152
0.29
chr16_78019925_78020076 0.27 Gm49589
predicted gene, 49589
26986
0.18
chr10_59403301_59404650 0.27 Pla2g12b
phospholipase A2, group XIIB
315
0.88
chr2_131495750_131496064 0.27 Smox
spermine oxidase
3643
0.22
chr13_83985373_83985609 0.27 Gm4241
predicted gene 4241
2500
0.29
chr9_37527353_37531611 0.27 Esam
endothelial cell-specific adhesion molecule
701
0.51
chr11_57011668_57012922 0.27 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
339
0.94
chr4_99654507_99655298 0.27 Gm12688
predicted gene 12688
81
0.94
chr2_72180632_72181101 0.27 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
1173
0.5
chr11_102364387_102365146 0.27 Slc4a1
solute carrier family 4 (anion exchanger), member 1
481
0.67
chr7_51624664_51625766 0.27 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
67
0.98
chr16_36420450_36420601 0.27 Gm49652
predicted gene, 49652
396
0.64
chr1_174175177_174176129 0.27 Spta1
spectrin alpha, erythrocytic 1
2877
0.14
chr8_99414293_99414856 0.27 Cdh8
cadherin 8
1745
0.36
chr1_86441904_86443224 0.27 Tex44
testis expressed 44
16235
0.11
chr3_154816919_154817899 0.26 Gm18589
predicted gene, 18589
22198
0.2
chr19_45238691_45239432 0.26 Lbx1
ladybird homeobox 1
3249
0.24
chr1_120269879_120270612 0.26 Steap3
STEAP family member 3
178
0.96
chr14_39469812_39470401 0.26 Nrg3
neuregulin 3
2560
0.44
chr7_141945515_141946556 0.26 Gm20501
predicted gene 20501
78
0.96
chr3_153849347_153849498 0.26 Asb17os
ankyrin repeat and SOCS box-containing 17, opposite strand
2979
0.13
chr7_141047534_141048391 0.26 Gm45299
predicted gene 45299
3627
0.1
chr7_19177965_19179153 0.26 Eml2
echinoderm microtubule associated protein like 2
2138
0.13
chr4_133874039_133874368 0.26 Rps6ka1
ribosomal protein S6 kinase polypeptide 1
528
0.63
chr2_52557337_52558561 0.26 Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
611
0.74
chr5_62764277_62764487 0.26 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
1738
0.46
chr6_122391330_122392825 0.26 1700063H04Rik
RIKEN cDNA 1700063H04 gene
698
0.58
chr1_133049808_133049959 0.26 Pik3c2b
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
3871
0.17
chr17_36874163_36874364 0.26 Trim10
tripartite motif-containing 10
4689
0.09
chr14_17171919_17173346 0.26 Gm48312
predicted gene, 48312
51129
0.16
chr6_54224153_54224304 0.26 Gm15527
predicted gene 15527
30683
0.15
chr10_75063274_75064120 0.25 Bcr
BCR activator of RhoGEF and GTPase
3105
0.22
chr11_24452380_24452616 0.25 Gm12068
predicted gene 12068
26252
0.18
chr13_59818297_59819205 0.25 Tut7
terminal uridylyl transferase 7
3837
0.13
chr5_139543263_139545139 0.25 Uncx
UNC homeobox
303
0.89
chr4_137047648_137048101 0.25 Zbtb40
zinc finger and BTB domain containing 40
821
0.59
chr12_17538828_17539186 0.25 Odc1
ornithine decarboxylase, structural 1
5787
0.16
chr13_83737592_83739114 0.25 Gm33366
predicted gene, 33366
182
0.66
chr11_4122925_4123415 0.25 Sec14l2
SEC14-like lipid binding 2
245
0.83
chr11_113291921_113292072 0.25 4732490B19Rik
RIKEN cDNA 4732490B19 gene
82327
0.1
chr5_39641486_39642467 0.25 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
2621
0.3
chr6_29694287_29695938 0.25 Tspan33
tetraspanin 33
878
0.58
chrX_12005788_12007643 0.25 Gm14512
predicted gene 14512
22247
0.22
chr7_46013267_46013496 0.25 Abcc6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
12312
0.11
chr14_99521583_99522333 0.25 Gm41230
predicted gene, 41230
587
0.8
chr12_91745342_91746056 0.25 Ston2
stonin 2
385
0.85
chr1_154725000_154725176 0.25 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
832
0.76
chr1_153654196_153654347 0.25 Rgs8
regulator of G-protein signaling 8
1246
0.39

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Hivep1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.8 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.5 GO:0097460 ferrous iron import into cell(GO:0097460)
0.1 0.3 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.3 GO:0061511 centriole elongation(GO:0061511)
0.1 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.1 0.1 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.3 GO:0072053 renal inner medulla development(GO:0072053)
0.1 1.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.1 0.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.8 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.3 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.2 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.4 GO:0001842 neural fold formation(GO:0001842)
0.1 0.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.2 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 0.2 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.1 0.5 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.3 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.1 0.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.2 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.9 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.3 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.3 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.1 GO:0098828 modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0070488 neutrophil aggregation(GO:0070488)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0051385 response to mineralocorticoid(GO:0051385)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.1 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:0019230 proprioception(GO:0019230)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.2 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 0.1 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0035482 gastric motility(GO:0035482)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.0 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.0 0.2 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.2 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:1903140 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.1 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.0 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.0 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.0 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.0 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:1902804 negative regulation of synaptic vesicle transport(GO:1902804)
0.0 0.0 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.4 GO:0007616 long-term memory(GO:0007616)
0.0 0.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:1902065 response to L-glutamate(GO:1902065)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.0 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.0 0.0 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.0 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.0 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.0 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.0 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.0 GO:0052041 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.0 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.0 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.0 GO:0072235 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0 0.0 GO:0040031 snRNA modification(GO:0040031)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.0 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0033504 floor plate development(GO:0033504)
0.0 0.0 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.1 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0070922 small RNA loading onto RISC(GO:0070922)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0014744 positive regulation of muscle adaptation(GO:0014744)
0.0 0.0 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0 0.1 GO:1901660 calcium ion export(GO:1901660)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.0 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.0 GO:0015888 thiamine transport(GO:0015888)
0.0 0.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.0 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.0 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.0 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.0 0.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.6 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0042567 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.0 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.0 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.0 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 0.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.7 GO:0015172 acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.3 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0043176 amine binding(GO:0043176)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0010851 cyclase regulator activity(GO:0010851)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.0 GO:0019976 interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0018640 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.0 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.0 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor