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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Hmx1

Z-value: 0.62

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Transcription factors associated with Hmx1

Gene Symbol	Gene ID	Gene Info
Hmx1 Ensembl NCBI MGI UniProt	ENSMUSG00000067438.3	H6 homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_35388341_35389287	Hmx1	294	0.512607	-0.29	2.7e-02	Click!
chr5_35389371_35389565	Hmx1	351	0.725062	-0.20	1.3e-01	Click!
chr5_35389846_35390469	Hmx1	1040	0.338614	-0.12	3.7e-01	Click!

Activity of the Hmx1 motif across conditions

Conditions sorted by the z-value of the Hmx1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_129216664_129219042	1.35	Pitx2	paired-like homeodomain transcription factor 2	3578	0.2
chr6_39494466_39494617	1.33	Dennd2a	DENN/MADD domain containing 2A	5375	0.17
chr13_4233789_4234486	1.31	Akr1c19	aldo-keto reductase family 1, member C19	397	0.81
chr7_120880267_120880570	1.30	Eef2k	eukaryotic elongation factor-2 kinase	4198	0.14
chr11_96343236_96346574	1.19	Hoxb3	homeobox B3	1136	0.24
chr2_158174901_158175285	1.07	1700060C20Rik	RIKEN cDNA 1700060C20 gene	16915	0.14
chr7_132778272_132778793	0.95	Fam53b	family with sequence similarity 53, member B	1616	0.39
chr8_121088119_121090419	0.95	Gm27530	predicted gene, 27530	4563	0.13
chr19_58453572_58455406	0.94	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	23	0.98
chr9_55282826_55283068	0.93	Nrg4	neuregulin 4	625	0.71
chr17_48448887_48449311	0.92	Tspo2	translocator protein 2	971	0.43
chr4_139336568_139337223	0.87	AL807811.1	aldo-keto reductase family 7 member A2 (AKR7A2) pseudogene	285	0.73
chr4_119188012_119188665	0.86	Ermap	erythroblast membrane-associated protein	409	0.69
chr5_75075112_75077490	0.85	Gsx2	GS homeobox 2	699	0.56
chr17_57227821_57228041	0.85	C3	complement component 3	72	0.95
chr7_105762080_105763247	0.82	Gm15645	predicted gene 15645	342	0.76
chr7_133700764_133701966	0.82	Uros	uroporphyrinogen III synthase	1173	0.35
chr19_25505518_25507191	0.81	Dmrt1	doublesex and mab-3 related transcription factor 1	647	0.72
chr12_103862299_103862565	0.79	Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	1119	0.32
chr12_103826543_103826975	0.76	Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	3614	0.12
chr2_167688724_167690153	0.75	Tmem189	transmembrane protein 189	384	0.52
chr8_84703616_84705950	0.72	Nfix	nuclear factor I/X	2933	0.13
chr12_84203794_84203995	0.72	Gm31513	predicted gene, 31513	7925	0.11
chr11_58927689_58928812	0.68	Btnl10	butyrophilin-like 10	10193	0.06
chr3_90368038_90368189	0.68	Gatad2b	GATA zinc finger domain containing 2B	16695	0.09
chr13_91461118_91462460	0.67	Ssbp2	single-stranded DNA binding protein 2	608	0.81
chr11_35951046_35951261	0.67	Wwc1	WW, C2 and coiled-coil domain containing 1	29374	0.19
chr2_168617972_168618123	0.65	Nfatc2	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2	16390	0.19
chr8_119437065_119437967	0.65	Osgin1	oxidative stress induced growth inhibitor 1	327	0.86
chr7_133114831_133116529	0.65	Ctbp2	C-terminal binding protein 2	2981	0.2
chr3_37987146_37987297	0.65	Gm42751	predicted gene 42751	4429	0.19
chr7_74421986_74422217	0.64	Gm7580	predicted gene 7580	29403	0.22
chr15_31529901_31531020	0.62	Marchf6	membrane associated ring-CH-type finger 6	593	0.65
chr8_46473091_46473536	0.62	Gm45244	predicted gene 45244	277	0.87
chr19_10015065_10016667	0.62	Rab3il1	RAB3A interacting protein (rabin3)-like 1	822	0.48
chr7_16416990_16417583	0.62	Gm45510	predicted gene 45510	665	0.51
chr16_85797970_85798654	0.61	Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	1326	0.51
chr8_72665204_72665522	0.61	Nwd1	NACHT and WD repeat domain containing 1	8277	0.15
chr15_80624523_80624695	0.60	Grap2	GRB2-related adaptor protein 2	1087	0.43
chr6_138143280_138143517	0.59	Mgst1	microsomal glutathione S-transferase 1	544	0.85
chr12_111833749_111833971	0.59	Zfyve21	zinc finger, FYVE domain containing 21	9095	0.11
chr11_98766918_98767150	0.59	Nr1d1	nuclear receptor subfamily 1, group D, member 1	3392	0.13
chr19_6634111_6634262	0.59	Gm14968	predicted gene 14968	11501	0.14
chr7_141654914_141655534	0.59	Muc6	mucin 6, gastric	84	0.96
chrX_53055829_53057122	0.58	C430049B03Rik	RIKEN cDNA C430049B03 gene	685	0.41
chr19_10523211_10524258	0.58	Sdhaf2	succinate dehydrogenase complex assembly factor 2	1358	0.25
chr5_64807638_64809344	0.56	Klf3	Kruppel-like factor 3 (basic)	3848	0.17
chr5_92236564_92236761	0.55	Ppef2	protein phosphatase, EF hand calcium-binding domain 2	7641	0.11
chr11_96939648_96939799	0.55	Pnpo	pyridoxine 5'-phosphate oxidase	4056	0.1
chr6_122391330_122392825	0.53	1700063H04Rik	RIKEN cDNA 1700063H04 gene	698	0.58
chr1_160306832_160307632	0.53	Rabgap1l	RAB GTPase activating protein 1-like	107	0.95
chr1_85933280_85934264	0.53	Gm28884	predicted gene 28884	3560	0.15
chr1_173330607_173330937	0.53	Ackr1	atypical chemokine receptor 1 (Duffy blood group)	2730	0.2
chr2_38286593_38287645	0.52	Dennd1a	DENN/MADD domain containing 1A	69	0.96
chr11_33202043_33204837	0.52	Tlx3	T cell leukemia, homeobox 3	149	0.86
chr5_8894454_8894838	0.52	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	697	0.63
chr7_67972762_67974418	0.52	Igf1r	insulin-like growth factor I receptor	20763	0.21
chr9_66505109_66505930	0.52	Herc1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	5265	0.18
chr11_46440435_46440727	0.52	Med7	mediator complex subunit 7	929	0.46
chr15_102955712_102957246	0.52	Hoxc11	homeobox C11	2052	0.15
chr17_33638155_33638934	0.51	Pram1	PML-RAR alpha-regulated adaptor molecule 1	449	0.7
chr11_96199669_96200892	0.51	Hoxb13	homeobox B13	5964	0.11
chr10_127177322_127177474	0.49	Slc26a10	solute carrier family 26, member 10	409	0.66
chr4_41271157_41271308	0.49	Ubap2	ubiquitin-associated protein 2	3884	0.13
chr17_36189137_36189654	0.48	H2-T3	histocompatibility 2, T region locus 3	727	0.28
chr17_35194091_35194242	0.48	Ltb	lymphotoxin B	273	0.61
chr17_25127118_25127513	0.47	Clcn7	chloride channel, voltage-sensitive 7	6076	0.1
chr19_60871718_60871869	0.47	Prdx3	peroxiredoxin 3	2763	0.19
chr17_28007198_28009699	0.46	Anks1	ankyrin repeat and SAM domain containing 1	1103	0.37
chr14_25841885_25843222	0.46	Anxa11	annexin A11	370	0.81
chr3_9767592_9767781	0.46	Gm16337	predicted gene 16337	10079	0.22
chr16_68205625_68205776	0.46	Gm49650	predicted gene, 49650	40845	0.21
chr19_4130763_4131308	0.45	Tmem134	transmembrane protein 134	3463	0.07
chr6_91116004_91117353	0.45	Nup210	nucleoporin 210	118	0.95
chr2_164432432_164433231	0.45	Sdc4	syndecan 4	10355	0.08
chr5_97000494_97000645	0.44	Bmp2k	BMP2 inducible kinase	2880	0.18
chr18_65802028_65802182	0.44	Sec11c	SEC11 homolog C, signal peptidase complex subunit	803	0.51
chr9_62340666_62341173	0.43	Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	374	0.87
chr9_48362869_48363160	0.43	Nxpe4	neurexophilin and PC-esterase domain family, member 4	973	0.55
chr3_51230467_51230944	0.43	Gm38357	predicted gene, 38357	1212	0.38
chr4_135727528_135728972	0.43	Il22ra1	interleukin 22 receptor, alpha 1	78	0.96
chr11_107992735_107992914	0.43	Gm11657	predicted gene 11657	1198	0.42
chr15_78571734_78572724	0.42	Rac2	Rac family small GTPase 2	552	0.62
chr7_16844794_16846016	0.42	Prkd2	protein kinase D2	172	0.9
chr15_62158174_62158844	0.42	Pvt1	Pvt1 oncogene	19666	0.25
chr13_114342850_114343360	0.42	Ndufs4	NADH:ubiquinone oxidoreductase core subunit S4	44944	0.12
chr4_132064709_132064928	0.42	Epb41	erythrocyte membrane protein band 4.1	7279	0.12
chr7_28584162_28584331	0.42	Pak4	p21 (RAC1) activated kinase 4	13840	0.08
chr5_143819014_143819653	0.42	Eif2ak1	eukaryotic translation initiation factor 2 alpha kinase 1	1386	0.38
chr6_67161907_67162479	0.41	A430010J10Rik	RIKEN cDNA A430010J10 gene	2731	0.23
chr6_87808529_87808706	0.41	Rab43	RAB43, member RAS oncogene family	1137	0.24
chr7_83651297_83652259	0.41	Il16	interleukin 16	3547	0.15
chr2_39002991_39003196	0.41	Rpl35	ribosomal protein L35	1950	0.16
chr10_118633408_118633559	0.41	Ifngas1	Ifng antisense RNA 1	76958	0.08
chr16_93129255_93129653	0.41	Gm28003	predicted gene, 28003	56699	0.15
chr15_50361344_50361976	0.40	Gm49198	predicted gene, 49198	74762	0.13
chr4_141617213_141618510	0.40	Tmem82	transmembrane protein 82	120	0.93
chr15_82166254_82166950	0.40	Srebf2	sterol regulatory element binding factor 2	18577	0.08
chr5_139812274_139812441	0.39	Tmem184a	transmembrane protein 184a	886	0.46
chr5_146686924_146687505	0.39	4930573C15Rik	RIKEN cDNA 4930573C15 gene	19408	0.16
chr7_120879515_120880256	0.39	Eef2k	eukaryotic elongation factor-2 kinase	3665	0.15
chr6_86078066_86079298	0.38	Add2	adducin 2 (beta)	598	0.65
chr5_145115755_145116764	0.38	Arpc1b	actin related protein 2/3 complex, subunit 1B	1943	0.18
chr8_121082801_121085531	0.38	Foxf1	forkhead box F1	220	0.71
chr13_117033409_117033738	0.38	Parp8	poly (ADP-ribose) polymerase family, member 8	8036	0.2
chr5_105527486_105528761	0.38	Lrrc8c	leucine rich repeat containing 8 family, member C	8650	0.2
chr18_32543718_32543992	0.38	Gypc	glycophorin C	8437	0.2
chr9_50922410_50922924	0.37	Gm25558	predicted gene, 25558	34717	0.13
chrX_143825863_143827628	0.37	Capn6	calpain 6	587	0.46
chr18_65246605_65246956	0.37	Mir122	microRNA 122	2081	0.24
chr9_46351879_46352155	0.37	Gm31374	predicted gene, 31374	9242	0.12
chr11_96294128_96295421	0.36	Hoxb6	homeobox B6	2298	0.11
chr1_136952214_136953356	0.36	Nr5a2	nuclear receptor subfamily 5, group A, member 2	845	0.67
chr13_56748368_56748842	0.36	Gm45623	predicted gene 45623	5222	0.24
chr1_191431994_191432741	0.36	Gm2272	predicted gene 2272	24701	0.12
chr5_115531466_115532555	0.36	Pxn	paxillin	10904	0.09
chr4_144423294_144423445	0.36	Pramef12	PRAME family member 12	14905	0.09
chr15_76368582_76369737	0.36	Hgh1	HGH1 homolog	261	0.77
chr19_5724002_5724609	0.36	Ehbp1l1	EH domain binding protein 1-like 1	1965	0.11
chrX_169915854_169917220	0.36	Mid1	midline 1	10414	0.22
chr18_76242126_76242702	0.36	Smad2	SMAD family member 2	240	0.92
chr2_36198146_36199404	0.36	Gm13429	predicted gene 13429	3539	0.16
chr1_160049724_160049981	0.35	4930523C07Rik	RIKEN cDNA 4930523C07 gene	5405	0.17
chr7_5029343_5032174	0.35	Zfp865	zinc finger protein 865	1434	0.15
chr2_91635021_91635643	0.35	F2	coagulation factor II	1063	0.36
chr13_24947671_24947822	0.35	Gpld1	glycosylphosphatidylinositol specific phospholipase D1	4594	0.15
chr9_99874679_99877472	0.35	Sox14	SRY (sex determining region Y)-box 14	95	0.97
chr3_9853920_9854071	0.35	Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	20316	0.17
chr10_94520068_94521446	0.35	Tmcc3	transmembrane and coiled coil domains 3	5900	0.23
chr7_101820668_101822582	0.35	Phox2a	paired-like homeobox 2a	879	0.38
chr1_138579548_138580048	0.35	Gm37101	predicted gene, 37101	8442	0.18
chr11_48873284_48874119	0.35	Irgm1	immunity-related GTPase family M member 1	2018	0.18
chr2_122237098_122237979	0.34	Sord	sorbitol dehydrogenase	2789	0.15
chr4_118544360_118544725	0.34	Tmem125	transmembrane protein 125	498	0.69
chr2_74725203_74725767	0.34	Mir10b	microRNA 10b	585	0.37
chr2_32061832_32061983	0.34	Gm16534	predicted gene 16534	2257	0.18
chr11_102318146_102319152	0.34	Ubtf	upstream binding transcription factor, RNA polymerase I	447	0.7
chr18_69665931_69667348	0.34	Tcf4	transcription factor 4	9972	0.29
chr4_134868934_134869297	0.34	Rhd	Rh blood group, D antigen	4579	0.19
chr16_18424546_18424973	0.34	Txnrd2	thioredoxin reductase 2	1625	0.21
chr13_93388547_93389010	0.34	Gm47155	predicted gene, 47155	22005	0.14
chr11_98581326_98581888	0.34	Ormdl3	ORM1-like 3 (S. cerevisiae)	5761	0.11
chr16_92489115_92489751	0.34	Clic6	chloride intracellular channel 6	3697	0.18
chr6_103674240_103674525	0.34	Chl1	cell adhesion molecule L1-like	23368	0.19
chr12_117729655_117729806	0.34	Gm18955	predicted gene, 18955	5758	0.23
chr10_82991418_82991936	0.33	Chst11	carbohydrate sulfotransferase 11	6179	0.19
chr6_141091497_141091720	0.33	Gm7384	predicted gene 7384	46439	0.16
chr11_40732046_40732503	0.33	Hmmr	hyaluronan mediated motility receptor (RHAMM)	1117	0.37
chr2_167588684_167589456	0.33	Gm11475	predicted gene 11475	2325	0.19
chr4_132040221_132040736	0.33	Gm13063	predicted gene 13063	7700	0.12
chr7_118853034_118853185	0.33	Knop1	lysine rich nucleolar protein 1	2504	0.19
chr9_72439224_72439615	0.33	Mns1	meiosis-specific nuclear structural protein 1	884	0.3
chr16_49798750_49798901	0.33	Gm15518	predicted gene 15518	45	0.97
chr17_33913300_33914237	0.33	Daxx	Fas death domain-associated protein	209	0.74
chr4_108217222_108218259	0.33	Zyg11a	zyg-11 family member A, cell cycle regulator	182	0.94
chr9_21015148_21016366	0.33	Icam1	intercellular adhesion molecule 1	228	0.81
chr15_79209083_79209599	0.33	Gm10863	predicted gene 10863	30	0.95
chr8_121570277_121571228	0.33	Fbxo31	F-box protein 31	7995	0.11
chr11_48869797_48870455	0.32	Irgm1	immunity-related GTPase family M member 1	1248	0.29
chr9_44340460_44342952	0.32	Hmbs	hydroxymethylbilane synthase	473	0.51
chr15_81585550_81586926	0.32	Ep300	E1A binding protein p300	18	0.58
chr15_91610712_91610863	0.32	4933438A12Rik	RIKEN cDNA 4933438A12 gene	13204	0.17
chr3_144759210_144759685	0.32	Clca3a1	chloride channel accessory 3A1	1394	0.3
chr16_92699485_92700446	0.32	Runx1	runt related transcription factor 1	2637	0.36
chr5_64803350_64804590	0.32	C230096K16Rik	RIKEN cDNA C230096K16 gene	44	0.56
chr12_108855592_108855779	0.32	Slc25a47	solute carrier family 25, member 47	4546	0.11
chr3_145987511_145989209	0.31	Syde2	synapse defective 1, Rho GTPase, homolog 2 (C. elegans)	223	0.93
chr4_3877971_3878122	0.31	Mos	Moloney sarcoma oncogene	5941	0.14
chr1_155736856_155738497	0.31	Lhx4	LIM homeobox protein 4	4351	0.18
chr8_61731359_61731510	0.31	Palld	palladin, cytoskeletal associated protein	28655	0.22
chr8_122480707_122480858	0.31	Ctu2	cytosolic thiouridylase subunit 2	140	0.89
chr14_44033999_44034275	0.31	Gm3287	predicted gene 3287	586	0.5
chr1_89921735_89923880	0.31	Gbx2	gastrulation brain homeobox 2	6378	0.21
chr4_49481203_49481354	0.31	Gm26424	predicted gene, 26424	6971	0.13
chr14_67263564_67263804	0.31	Gm23178	predicted gene, 23178	11279	0.16
chr9_63144078_63146888	0.31	Skor1	SKI family transcriptional corepressor 1	1497	0.38
chr16_23061643_23061794	0.31	Kng1	kininogen 1	3325	0.1
chr7_67655369_67656000	0.31	Ttc23	tetratricopeptide repeat domain 23	237	0.9
chr4_57914999_57916744	0.31	D630039A03Rik	RIKEN cDNA D630039A03 gene	426	0.84
chr16_92058346_92059208	0.31	Mrps6	mitochondrial ribosomal protein S6	36	0.8
chr13_31546831_31546982	0.31	Foxq1	forkhead box Q1	9228	0.14
chr8_121791189_121791340	0.30	Klhdc4	kelch domain containing 4	6164	0.13
chr5_130016232_130016383	0.30	Asl	argininosuccinate lyase	1585	0.26
chr10_81563960_81565660	0.30	Tle5	TLE family member 5, transcriptional modulator	205	0.84
chr2_162967542_162967693	0.30	Gm11453	predicted gene 11453	15644	0.11
chr1_153413763_153413914	0.30	E330020D12Rik	Riken cDNA E330020D12 gene	395	0.81
chr6_52239036_52239383	0.30	Hoxa10	homeobox A10	1586	0.13
chr4_77911888_77912039	0.30	Ptprd	protein tyrosine phosphatase, receptor type, D	299776	0.01
chr7_118742325_118742557	0.30	1700016B15Rik	RIKEN cDNA 1700016B15 gene	1260	0.29
chr7_68189508_68190188	0.30	Igf1r	insulin-like growth factor I receptor	3223	0.28
chr10_59873887_59874700	0.30	Gm7413	predicted gene 7413	2611	0.21
chr17_26117534_26117685	0.29	Tmem8	transmembrane protein 8	220	0.84
chr19_9954351_9955257	0.29	Gm50346	predicted gene, 50346	11972	0.09
chr4_106924547_106925049	0.29	Ssbp3	single-stranded DNA binding protein 3	1573	0.42
chr16_44174924_44175152	0.29	Usf3	upstream transcription factor family member 3	1641	0.38
chr14_30942231_30942467	0.29	Itih1	inter-alpha trypsin inhibitor, heavy chain 1	928	0.4
chr19_34744341_34744492	0.29	Slc16a12	solute carrier family 16 (monocarboxylic acid transporters), member 12	2873	0.17
chrX_101256637_101256923	0.29	Foxo4	forkhead box O4	1959	0.16
chr9_107375414_107375565	0.29	4930429P21Rik	RIKEN cDNA 4930429P21 gene	21503	0.09
chr4_44778425_44778576	0.29	Zcchc7	zinc finger, CCHC domain containing 7	18056	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.2	0.5	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.2	0.5	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.4	GO:0048371	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.1	0.9	GO:1900107	regulation of nodal signaling pathway(GO:1900107)
0.1	0.4	GO:0089700	protein kinase D signaling(GO:0089700)
0.1	0.4	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.1	0.5	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.3	GO:0045472	response to ether(GO:0045472)
0.1	0.3	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1	0.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.2	GO:0018992	germ-line sex determination(GO:0018992)
0.1	0.2	GO:0002432	granuloma formation(GO:0002432)
0.1	0.5	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.1	0.4	GO:0021546	rhombomere development(GO:0021546)
0.1	0.4	GO:0034227	tRNA thio-modification(GO:0034227)
0.1	0.2	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1	0.2	GO:0036166	phenotypic switching(GO:0036166)
0.1	0.2	GO:0061144	alveolar secondary septum development(GO:0061144)
0.1	0.2	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.1	0.3	GO:0030035	microspike assembly(GO:0030035)
0.1	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1	0.2	GO:1902065	response to L-glutamate(GO:1902065)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.4	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.2	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.1	0.2	GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.1	1.0	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.2	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	0.2	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.3	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.1	0.3	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.2	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.1	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1	0.3	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.1	0.2	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1	0.2	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.1	0.4	GO:0015825	L-serine transport(GO:0015825)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.4	GO:0018065	protein-cofactor linkage(GO:0018065)
0.1	0.2	GO:0002325	natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0	0.1	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.6	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0021558	trochlear nerve development(GO:0021558)
0.0	0.1	GO:0072050	S-shaped body morphogenesis(GO:0072050)
0.0	0.1	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.1	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0	0.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.2	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.0	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.2	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.0	0.1	GO:0090272	negative regulation of fibroblast growth factor production(GO:0090272)
0.0	0.2	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.0	0.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.1	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.1	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0048818	positive regulation of hair follicle maturation(GO:0048818)
0.0	0.1	GO:0061043	regulation of vascular wound healing(GO:0061043)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.3	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.2	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.3	GO:0060347	heart trabecula formation(GO:0060347)
0.0	0.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.2	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.1	GO:0021550	medulla oblongata development(GO:0021550)
0.0	0.4	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.2	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.0	GO:0001905	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0	0.1	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.3	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.1	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0042519	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.2	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.5	GO:0033014	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0	0.1	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.0	GO:0032672	regulation of interleukin-3 production(GO:0032672)
0.0	0.1	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.4	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.2	GO:0070944	neutrophil mediated killing of bacterium(GO:0070944)
0.0	0.5	GO:0048665	neuron fate specification(GO:0048665)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.0	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0034633	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.1	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.0	GO:0021843	substrate-independent telencephalic tangential migration(GO:0021826) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.0	0.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.3	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.1	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0	0.1	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.2	GO:0097421	liver regeneration(GO:0097421)
0.0	0.2	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.0	GO:0060847	endothelial cell fate specification(GO:0060847)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.1	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0	0.2	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.0	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.0	0.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.1	GO:0071684	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0	0.1	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990)
0.0	0.1	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.3	GO:0046688	response to copper ion(GO:0046688)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.0	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.1	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.0	GO:1905063	regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.5	GO:0006953	acute-phase response(GO:0006953)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.0	0.1	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.2	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
0.0	0.3	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.0	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.0	GO:0070384	Harderian gland development(GO:0070384)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.1	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.1	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.2	GO:0008272	sulfate transport(GO:0008272)
0.0	0.0	GO:0070488	neutrophil aggregation(GO:0070488)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0032532	regulation of microvillus length(GO:0032532)
0.0	0.0	GO:0046016	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0	0.1	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:0042168	heme metabolic process(GO:0042168)
0.0	0.1	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0071801	regulation of podosome assembly(GO:0071801)
0.0	0.0	GO:0048819	regulation of hair follicle maturation(GO:0048819)
0.0	0.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.0	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.0	0.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.0	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.0	GO:0097460	ferrous iron import into cell(GO:0097460)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0033121	regulation of purine nucleotide catabolic process(GO:0033121)
0.0	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.0	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.3	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.0	GO:0061626	pharyngeal arch artery morphogenesis(GO:0061626)
0.0	0.1	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0	0.0	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.0	GO:0015684	ferrous iron transport(GO:0015684)
0.0	0.0	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.0	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0	0.1	GO:0035437	maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0060717	chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0051446	positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0014870	response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.1	GO:0044598	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.0	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	0.0	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0036065	fucosylation(GO:0036065)
0.0	0.1	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392)
0.0	0.1	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.0	0.0	GO:0090194	negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
0.0	0.0	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.3	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.1	0.2	GO:0044393	microspike(GO:0044393)
0.0	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.2	GO:0032437	cuticular plate(GO:0032437)
0.0	0.4	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.3	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.1	GO:0033010	paranodal junction(GO:0033010)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.5	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0036128	CatSper complex(GO:0036128)
0.0	0.2	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.4	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.3	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.1	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.0	0.1	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.0	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.1	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	1.3	GO:0072562	blood microparticle(GO:0072562)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.6	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.0	GO:1990246	uniplex complex(GO:1990246)
0.0	0.0	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.4	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.2	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.1	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.2	GO:0042731	PH domain binding(GO:0042731)
0.1	0.3	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.2	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.3	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.2	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.3	GO:0043559	insulin binding(GO:0043559)
0.0	0.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	1.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.3	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.4	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	1.7	GO:0005178	integrin binding(GO:0005178)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0034805	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0	0.0	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0	0.2	GO:0043176	amine binding(GO:0043176)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.3	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.0	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.0	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.4	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.0	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	1.8	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	0.0	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.3	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.0	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.5	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.6	PID FGF PATHWAY	FGF signaling pathway
0.0	0.2	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.1	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.4	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.0	REACTOME PI 3K CASCADE	Genes involved in PI-3K cascade
0.0	0.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK

Results for Hmx1

Z-value: 0.62

Motif logo

Transcription factors associated with Hmx1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hmx1 motif across conditions

Conditions sorted by the z-value of the Hmx1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: