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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Hsf1

Z-value: 0.84

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Transcription factors associated with Hsf1

Gene Symbol	Gene ID	Gene Info
Hsf1 Ensembl NCBI MGI UniProt	ENSMUSG00000022556.9	heat shock factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr15_76477842_76478617	Hsf1	543	0.467598	-0.34	8.1e-03	Click!
chr15_76480396_76480562	Hsf1	2793	0.108724	-0.22	9.3e-02	Click!
chr15_76480965_76481116	Hsf1	3354	0.098436	-0.17	1.8e-01	Click!
chr15_76478890_76479041	Hsf1	1279	0.209534	-0.14	2.9e-01	Click!
chr15_76483200_76483351	Hsf1	5589	0.082258	-0.14	3.0e-01	Click!

Activity of the Hsf1 motif across conditions

Conditions sorted by the z-value of the Hsf1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_48300015_48301474	3.27	Treml2	triggering receptor expressed on myeloid cells-like 2	358	0.8
chr4_142017816_142018715	2.94	4930455G09Rik	RIKEN cDNA 4930455G09 gene	367	0.8
chr3_14889110_14890285	2.92	Car2	carbonic anhydrase 2	3058	0.25
chr5_139793988_139794176	2.73	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	2548	0.18
chr6_120819964_120820819	2.23	Atp6v1e1	ATPase, H+ transporting, lysosomal V1 subunit E1	1992	0.25
chr6_135199945_135200188	1.99	Fam234b	family with sequence similarity 234, member B	1654	0.23
chr17_45592643_45594205	1.98	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	210	0.86
chr2_163548522_163549154	1.88	Hnf4a	hepatic nuclear factor 4, alpha	1245	0.35
chr2_4560599_4561970	1.79	Frmd4a	FERM domain containing 4A	1509	0.43
chr6_31612888_31614126	1.78	Gm43154	predicted gene 43154	8218	0.19
chr11_58199579_58200256	1.78	Irgm2	immunity-related GTPase family M member 2	299	0.49
chrX_157701658_157702782	1.64	Smpx	small muscle protein, X-linked	378	0.83
chr10_80330985_80331440	1.62	Reep6	receptor accessory protein 6	1010	0.24
chr17_84728381_84728656	1.61	Lrpprc	leucine-rich PPR-motif containing	2666	0.24
chr3_28698049_28698538	1.61	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	276	0.91
chr7_66196444_66196724	1.59	Gm45080	predicted gene 45080	6029	0.17
chr8_117297360_117297630	1.58	Cmip	c-Maf inducing protein	40378	0.17
chr19_5842021_5842539	1.58	Neat1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	2979	0.1
chr11_115804413_115805142	1.56	Caskin2	CASK-interacting protein 2	3325	0.12
chr13_49308099_49309227	1.56	Fgd3	FYVE, RhoGEF and PH domain containing 3	577	0.76
chr16_91086509_91086728	1.50	4932438H23Rik	RIKEN cDNA 4932438H23 gene	8504	0.12
chr11_109613330_109613686	1.47	Wipi1	WD repeat domain, phosphoinositide interacting 1	1541	0.32
chr10_8944239_8945864	1.47	Gm48728	predicted gene, 48728	6898	0.2
chr6_88637167_88637346	1.45	Kbtbd12	kelch repeat and BTB (POZ) domain containing 12	694	0.69
chr10_12962231_12962395	1.45	Stx11	syntaxin 11	1945	0.33
chr13_94382387_94382639	1.44	Ap3b1	adaptor-related protein complex 3, beta 1 subunit	23553	0.16
chr2_32650084_32650827	1.43	Mir1954	microRNA 1954	1874	0.14
chr19_5842574_5845856	1.42	Neat1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	1044	0.25
chr13_24420457_24420628	1.41	Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	3318	0.18
chr4_47294936_47295168	1.39	Col15a1	collagen, type XV, alpha 1	6765	0.24
chr6_34599135_34600037	1.38	Cald1	caldesmon 1	966	0.58
chr11_102892824_102894139	1.36	Gfap	glial fibrillary acidic protein	3650	0.12
chr9_50752994_50754649	1.36	Cryab	crystallin, alpha B	574	0.54
chr6_51129516_51130052	1.34	Mir148a	microRNA 148a	140126	0.04
chr8_68211695_68212166	1.34	Psd3	pleckstrin and Sec7 domain containing 3	97	0.98
chr13_41019834_41020226	1.33	Tmem14c	transmembrane protein 14C	3738	0.15
chr14_75069008_75069423	1.33	Rubcnl	RUN and cysteine rich domain containing beclin 1 interacting protein like	32593	0.14
chr11_49186633_49187052	1.32	Btnl9	butyrophilin-like 9	195	0.9
chr1_171681296_171681488	1.32	A630035G10Rik	RIKEN cDNA A630035G10 gene	541	0.38
chr19_3986544_3987096	1.31	Acy3	aspartoacylase (aminoacylase) 3	159	0.85
chr18_82490406_82490701	1.29	Mbp	myelin basic protein	15183	0.17
chr12_84962187_84962549	1.29	Arel1	apoptosis resistant E3 ubiquitin protein ligase 1	3662	0.16
chr1_33668089_33668370	1.29	Prim2	DNA primase, p58 subunit	1566	0.23
chr15_78246088_78246239	1.29	Ncf4	neutrophil cytosolic factor 4	1319	0.35
chr2_166080710_166081069	1.29	Sulf2	sulfatase 2	2770	0.25
chr8_119798276_119799129	1.28	Meak7	MTOR associated protein , eak-7 homolog	20286	0.14
chr11_43900050_43900201	1.27	Adra1b	adrenergic receptor, alpha 1b	1085	0.62
chr11_55417729_55419811	1.27	Sparc	secreted acidic cysteine rich glycoprotein	1128	0.44
chr15_66811887_66812132	1.25	Sla	src-like adaptor	584	0.76
chrX_53053916_53055220	1.25	Mir322	microRNA 322	219	0.66
chr10_54038077_54038509	1.25	Gm47917	predicted gene, 47917	25518	0.18
chr4_129272158_129273149	1.25	Gm12976	predicted gene 12976	8923	0.11
chr9_71215350_71216642	1.24	Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	207	0.95
chr2_167539777_167540513	1.24	Snai1	snail family zinc finger 1	1950	0.22
chr1_136469566_136469940	1.24	Kif14	kinesin family member 14	750	0.59
chr12_28622635_28623340	1.24	Colec11	collectin sub-family member 11	273	0.88
chr1_189687202_189688055	1.23	Cenpf	centromere protein F	407	0.82
chr19_47384312_47384494	1.23	Sh3pxd2a	SH3 and PX domains 2A	25956	0.18
chr3_146328120_146328802	1.22	Gm43334	predicted gene 43334	4041	0.21
chr2_129233051_129233346	1.21	9830144P21Rik	RIKEN cDNA 9830144P21 gene	2619	0.14
chr6_120174764_120175262	1.20	Ninj2	ninjurin 2	18810	0.18
chr10_69151959_69152320	1.19	Rhobtb1	Rho-related BTB domain containing 1	705	0.5
chr12_109455257_109457986	1.18	Dlk1	delta like non-canonical Notch ligand 1	2426	0.16
chr4_156058523_156059788	1.18	Ttll10	tubulin tyrosine ligase-like family, member 10	189	0.76
chr8_84021064_84022448	1.18	Palm3	paralemmin 3	285	0.75
chr8_36608403_36609754	1.18	Dlc1	deleted in liver cancer 1	4796	0.31
chr9_76237840_76238320	1.18	Gfral	GDNF family receptor alpha like	24423	0.21
chr16_87712189_87713161	1.16	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	13671	0.21
chr9_107982030_107984233	1.15	Gm20661	predicted gene 20661	38	0.54
chr5_118360340_118360644	1.14	Gm28563	predicted gene 28563	36838	0.15
chr5_114173960_114175108	1.14	Acacb	acetyl-Coenzyme A carboxylase beta	1372	0.35
chr6_136940269_136941762	1.14	Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	488	0.73
chr7_70280148_70281631	1.13	Gm29327	predicted gene 29327	31113	0.13
chr2_64975471_64975858	1.13	Grb14	growth factor receptor bound protein 14	82	0.98
chr3_14877670_14878139	1.13	Car2	carbonic anhydrase 2	8369	0.19
chr4_129463918_129464422	1.12	Bsdc1	BSD domain containing 1	372	0.74
chr2_10128810_10129045	1.12	Itih2	inter-alpha trypsin inhibitor, heavy chain 2	1736	0.25
chr17_43025924_43026123	1.12	Tnfrsf21	tumor necrosis factor receptor superfamily, member 21	9455	0.29
chr14_69273653_69274347	1.11	Gm20236	predicted gene, 20236	8140	0.09
chr14_48538424_48539155	1.09	4930572G02Rik	RIKEN cDNA 4930572G02 gene	430	0.76
chr19_37696064_37698588	1.09	Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	472	0.8
chr5_113798574_113798890	1.08	Tmem119	transmembrane protein 119	1714	0.21
chr13_21933713_21934661	1.06	Gm44456	predicted gene, 44456	9171	0.06
chr14_69491925_69492597	1.04	Gm37094	predicted gene, 37094	8129	0.1
chr7_24400757_24400977	1.03	Smg9	smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)	946	0.37
chr2_73059799_73060049	1.02	Gm13665	predicted gene 13665	56824	0.09
chr18_80259007_80259392	1.02	Slc66a2	solute carrier family 66 member 2	2881	0.16
chr16_88561792_88563295	1.02	Cldn8	claudin 8	640	0.64
chr10_58395820_58396456	1.00	Lims1	LIM and senescent cell antigen-like domains 1	1750	0.37
chr3_102086617_102087454	1.00	Casq2	calsequestrin 2	396	0.81
chr18_11051784_11053949	1.00	Gata6	GATA binding protein 6	178	0.66
chr15_77338142_77338550	0.99	Gm49436	predicted gene, 49436	28353	0.1
chr1_33756799_33758007	0.99	Bag2	BCL2-associated athanogene 2	324	0.84
chr13_37860695_37860981	0.99	Rreb1	ras responsive element binding protein 1	2904	0.28
chr16_92692883_92693516	0.99	Runx1	runt related transcription factor 1	2296	0.38
chr6_134933502_134933685	0.97	Gm44238	predicted gene, 44238	3481	0.14
chr3_149497202_149497672	0.97	Gm30382	predicted gene, 30382	52136	0.17
chr6_38355123_38355426	0.95	Zc3hav1	zinc finger CCCH type, antiviral 1	671	0.59
chr13_52986026_52986367	0.94	Nfil3	nuclear factor, interleukin 3, regulated	5123	0.19
chr13_60737782_60738368	0.94	Dapk1	death associated protein kinase 1	15921	0.15
chr7_37336508_37338401	0.94	6720469O03Rik	RIKEN cDNA 6720469O03 gene	29176	0.19
chr10_45473706_45474109	0.94	Lin28b	lin-28 homolog B (C. elegans)	3706	0.27
chr5_119676904_119677966	0.93	Tbx3	T-box 3	1990	0.25
chr8_121170748_121171459	0.93	Gm37609	predicted gene, 37609	30160	0.12
chr17_88628874_88630550	0.92	Ston1	stonin 1	2348	0.25
chr4_46038779_46040179	0.91	Tmod1	tropomodulin 1	270	0.92
chr11_99437637_99438403	0.91	Krt20	keratin 20	130	0.92
chr4_136175397_136175565	0.90	E2f2	E2F transcription factor 2	3087	0.19
chr15_78402289_78402941	0.89	Tst	thiosulfate sulfurtransferase, mitochondrial	3237	0.12
chr19_5847515_5849685	0.89	Frmd8os	FERM domain containing 8, opposite strand	92	0.92
chr11_32280517_32281064	0.89	Hba-a1	hemoglobin alpha, adult chain 1	2721	0.14
chr1_150991583_150991734	0.88	Hmcn1	hemicentin 1	1393	0.42
chr18_84854414_84854902	0.87	Cyb5a	cytochrome b5 type A (microsomal)	311	0.87
chr8_68954395_68954546	0.87	Gm45780	predicted gene 45780	4149	0.23
chr6_138143888_138144427	0.87	Mgst1	microsomal glutathione S-transferase 1	1303	0.58
chr18_81426872_81427316	0.87	Gm30288	predicted gene, 30288	26878	0.21
chr7_75609900_75610850	0.87	Akap13	A kinase (PRKA) anchor protein 13	336	0.9
chr14_46830775_46830938	0.87	Gm10101	predicted gene 10101	1171	0.24
chr16_91864599_91864796	0.87	Itsn1	intersectin 1 (SH3 domain protein 1A)	2671	0.23
chr19_43888532_43890580	0.86	Dnmbp	dynamin binding protein	1135	0.42
chr10_86302733_86303435	0.86	Timp3	tissue inhibitor of metalloproteinase 3	230	0.95
chr6_87152805_87153055	0.86	Gm44415	predicted gene, 44415	12078	0.15
chr1_91227573_91227939	0.85	Ube2f	ubiquitin-conjugating enzyme E2F (putative)	22548	0.13
chr16_36364816_36365168	0.85	Gm15845	predicted gene 15845	2078	0.12
chr5_116420481_116421179	0.85	Hspb8	heat shock protein 8	2034	0.22
chr7_27448641_27448983	0.84	Blvrb	biliverdin reductase B (flavin reductase (NADPH))	751	0.39
chr18_36342529_36342821	0.84	Cystm1	cysteine-rich transmembrane module containing 1	3	0.98
chr14_76520833_76521078	0.84	E130202H07Rik	RIKEN cDNA E130202H07 gene	5637	0.21
chr7_6694119_6695702	0.84	Zim1	zinc finger, imprinted 1	1519	0.27
chr10_69344778_69344971	0.83	Cdk1	cyclin-dependent kinase 1	560	0.74
chr4_46402358_46402517	0.82	Hemgn	hemogen	1799	0.25
chr12_7978894_7979569	0.82	Apob	apolipoprotein B	1452	0.45
chr1_78202945_78204367	0.81	Pax3	paired box 3	6522	0.23
chr4_150568510_150568661	0.81	Gm13091	predicted gene 13091	41	0.96
chr6_129275114_129275355	0.80	Cd69	CD69 antigen	132	0.94
chr14_65832957_65833923	0.79	Esco2	establishment of sister chromatid cohesion N-acetyltransferase 2	468	0.79
chr5_32461820_32462037	0.79	Gm43312	predicted gene 43312	2100	0.19
chr13_60497532_60497707	0.78	A530001N23Rik	RIKEN cDNA A530001N23 gene	8811	0.17
chr3_51232410_51232571	0.78	Gm38357	predicted gene, 38357	573	0.68
chr8_10996746_10997038	0.77	9530052E02Rik	RIKEN cDNA 9530052E02 gene	10958	0.12
chr12_16836096_16836591	0.77	E2f6	E2F transcription factor 6	12192	0.14
chr15_53202547_53202898	0.77	Ext1	exostosin glycosyltransferase 1	6467	0.33
chr12_99349391_99349819	0.76	3300002A11Rik	RIKEN cDNA 3300002A11 gene	3207	0.17
chr5_38501689_38501958	0.76	Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	256	0.9
chr11_58961317_58962255	0.76	H3f4	H3.4 histone	26	0.92
chr11_94999021_94999698	0.76	Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	3295	0.14
chr15_67172735_67173470	0.76	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	3610	0.32
chr19_37555723_37555955	0.75	Exoc6	exocyst complex component 6	5380	0.23
chr1_33753963_33754137	0.75	Bag2	BCL2-associated athanogene 2	3677	0.16
chr7_75587930_75588234	0.75	Akap13	A kinase (PRKA) anchor protein 13	21957	0.17
chr15_78447752_78448542	0.75	Tmprss6	transmembrane serine protease 6	3768	0.13
chr7_28867501_28867875	0.74	Lgals7	lectin, galactose binding, soluble 7	3233	0.11
chr2_28619735_28619886	0.74	Gfi1b	growth factor independent 1B	2135	0.19
chr12_84150828_84152588	0.74	Pnma1	paraneoplastic antigen MA1	3219	0.13
chr5_116026440_116026761	0.74	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	2092	0.2
chr1_133689442_133689593	0.74	Lax1	lymphocyte transmembrane adaptor 1	569	0.67
chr7_115859429_115859864	0.73	Sox6	SRY (sex determining region Y)-box 6	206	0.97
chr8_87656224_87657234	0.73	4933402J07Rik	RIKEN cDNA 4933402J07 gene	92876	0.07
chr15_78926966_78928482	0.73	Lgals1	lectin, galactose binding, soluble 1	998	0.29
chr11_101551182_101551915	0.73	Brca1	breast cancer 1, early onset	34	0.9
chr11_98446534_98448432	0.73	Grb7	growth factor receptor bound protein 7	415	0.68
chr16_55555475_55555702	0.73	Gm23003	predicted gene, 23003	39300	0.18
chr9_110989233_110989717	0.73	Gm10030	predicted gene 10030	24	0.62
chr8_121114339_121115833	0.72	Foxc2	forkhead box C2	1085	0.37
chr15_25942218_25942426	0.72	Retreg1	reticulophagy regulator 1	357	0.88
chr2_163550072_163550262	0.71	Hnf4a	hepatic nuclear factor 4, alpha	84	0.96
chr4_108360061_108360767	0.71	Shisal2a	shisa like 2A	22935	0.11
chr10_80834399_80836114	0.71	Mir1982	microRNA 1982	6459	0.07
chr10_89769073_89769465	0.71	Uhrf1bp1l	UHRF1 (ICBP90) binding protein 1-like	17931	0.18
chr11_95012524_95013312	0.71	Samd14	sterile alpha motif domain containing 14	2637	0.16
chr6_88916373_88916858	0.71	Gm44178	predicted gene, 44178	3093	0.16
chr7_4509417_4510506	0.71	Tnnt1	troponin T1, skeletal, slow	23	0.94
chr7_140767252_140767403	0.70	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	2846	0.13
chr14_20663037_20663711	0.70	Synpo2l	synaptopodin 2-like	1200	0.26
chr2_28597559_28598147	0.70	Gm22675	predicted gene, 22675	2726	0.15
chr4_58992141_58992399	0.70	Dnajc25	DnaJ heat shock protein family (Hsp40) member C25	2792	0.19
chr1_89015582_89015939	0.70	1700067G17Rik	RIKEN cDNA 1700067G17 gene	353	0.88
chr5_114374300_114374658	0.70	Kctd10	potassium channel tetramerisation domain containing 10	2337	0.21
chrX_52783996_52784386	0.69	Gm7851	predicted gene 7851	1175	0.3
chr2_146098163_146098385	0.69	Cfap61	cilia and flagella associated protein 61	51023	0.15
chr13_51648729_51649046	0.68	Gm22806	predicted gene, 22806	688	0.62
chr5_123877664_123878528	0.68	Hcar1	hydrocarboxylic acid receptor 1	1924	0.23
chr3_105701142_105701902	0.68	Inka2	inka box actin regulator 2	3077	0.16
chr18_61651079_61652393	0.68	Mir143	microRNA 143	2478	0.16
chr10_40141207_40142674	0.68	Slc16a10	solute carrier family 16 (monocarboxylic acid transporters), member 10	314	0.85
chr6_60826003_60826617	0.67	Snca	synuclein, alpha	1246	0.48
chr10_130322862_130323013	0.67	Tespa1	thymocyte expressed, positive selection associated 1	58	0.97
chr5_109557571_109558777	0.67	Crlf2	cytokine receptor-like factor 2	762	0.58
chr1_133470621_133470772	0.67	Sox13	SRY (sex determining region Y)-box 13	46319	0.12
chr10_25253128_25253550	0.67	Gm7791	predicted gene 7791	1839	0.31
chr6_35277861_35278262	0.67	Slc13a4	solute carrier family 13 (sodium/sulfate symporters), member 4	10113	0.15
chr17_30626621_30627197	0.67	1700097N02Rik	RIKEN cDNA 1700097N02 gene	4	0.34
chr15_102955712_102957246	0.66	Hoxc11	homeobox C11	2052	0.15
chr17_78300253_78300404	0.66	Gm25069	predicted gene, 25069	2333	0.3
chr11_61075424_61076210	0.66	Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	10013	0.17
chr19_17348783_17349185	0.66	Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	7683	0.23
chr7_19361226_19361886	0.66	Ppp1r13l	protein phosphatase 1, regulatory subunit 13 like	340	0.68
chrX_143822347_143822757	0.66	Capn6	calpain 6	4780	0.24
chr8_23035959_23037041	0.66	Ank1	ankyrin 1, erythroid	1269	0.45
chr13_4233789_4234486	0.66	Akr1c19	aldo-keto reductase family 1, member C19	397	0.81

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.5	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.4	1.5	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.3	1.3	GO:0035799	ureter maturation(GO:0035799)
0.3	1.0	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.3	0.9	GO:0042938	dipeptide transport(GO:0042938)
0.3	0.9	GO:0018094	protein polyglycylation(GO:0018094)
0.3	0.8	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3	0.8	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3	0.8	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2	0.9	GO:0003166	bundle of His development(GO:0003166)
0.2	0.9	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.2	0.9	GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.2	0.9	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.2	0.6	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.2	0.6	GO:0034421	post-translational protein acetylation(GO:0034421)
0.2	0.8	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.2	0.6	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.2	0.4	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.2	0.5	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2	0.9	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.2	0.5	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.2	0.7	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.2	0.5	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.2	0.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2	0.6	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.2	0.5	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.2	0.6	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.2	0.5	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2	2.1	GO:0015858	nucleoside transport(GO:0015858)
0.2	0.5	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.4	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.1	0.4	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.6	GO:0052055	modulation by symbiont of host molecular function(GO:0052055)
0.1	0.4	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.1	0.4	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.7	GO:0010957	negative regulation of vitamin D biosynthetic process(GO:0010957)
0.1	0.7	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.1	0.4	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1	0.3	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.1	0.5	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.1	0.5	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1	0.9	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	0.5	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.2	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.5	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.1	0.7	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.4	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.1	0.4	GO:0007418	ventral midline development(GO:0007418)
0.1	0.4	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1	0.3	GO:0018992	germ-line sex determination(GO:0018992)
0.1	0.3	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	0.3	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1	0.7	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.3	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.1	0.3	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.6	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.5	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.5	GO:0009249	protein lipoylation(GO:0009249)
0.1	0.3	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.1	0.5	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.6	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	1.4	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	0.6	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.2	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.1	0.4	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.1	0.4	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	0.3	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1	0.2	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.1	0.4	GO:0072675	osteoclast fusion(GO:0072675)
0.1	0.6	GO:0043320	natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1	0.2	GO:0009826	unidimensional cell growth(GO:0009826)
0.1	0.3	GO:0006742	NADP catabolic process(GO:0006742)
0.1	0.4	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.2	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.2	GO:0042908	xenobiotic transport(GO:0042908)
0.1	0.2	GO:0071233	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1	0.3	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1	0.3	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1	0.2	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1	0.2	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.1	0.4	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
0.1	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.1	0.7	GO:0046415	urate metabolic process(GO:0046415)
0.1	0.3	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.2	GO:0072697	protein localization to cell cortex(GO:0072697)
0.1	0.5	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.1	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1	0.5	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.6	GO:0030575	nuclear body organization(GO:0030575)
0.1	0.4	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.1	0.2	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
0.1	0.3	GO:0018214	protein carboxylation(GO:0018214)
0.1	0.3	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.3	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.1	0.4	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.1	0.2	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.1	0.4	GO:0002911	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1	0.1	GO:0046102	inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1	0.2	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.1	0.1	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.1	0.3	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	0.4	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.4	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.3	GO:0030916	otic vesicle formation(GO:0030916)
0.1	0.2	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.1	0.4	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.1	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.1	0.1	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.1	0.2	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1	0.1	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.1	GO:0006680	glucosylceramide catabolic process(GO:0006680)
0.1	0.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1	0.1	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.1	0.2	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	0.2	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1	0.4	GO:0036089	cleavage furrow formation(GO:0036089)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.2	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.2	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.2	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888)
0.0	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.2	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.6	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.3	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.2	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.1	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.4	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.3	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.3	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.3	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.2	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.9	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:2000389	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0	0.1	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.2	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.2	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.2	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.3	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.1	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	1.2	GO:0006778	porphyrin-containing compound metabolic process(GO:0006778)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.9	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	1.0	GO:0021591	ventricular system development(GO:0021591)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	1.3	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	0.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.4	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.2	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.2	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.0	0.4	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.0	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.2	GO:0050812	regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.0	GO:0010958	regulation of amino acid import(GO:0010958)
0.0	0.4	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0072672	neutrophil extravasation(GO:0072672)
0.0	0.1	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.2	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0	0.4	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:1902023	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.4	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.2	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.1	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.2	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.3	GO:0019054	modulation by virus of host process(GO:0019054)
0.0	0.1	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.0	0.2	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.2	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.7	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.3	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.6	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:0033216	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.4	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.5	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.2	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.1	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.0	GO:0002363	alpha-beta T cell lineage commitment(GO:0002363)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.1	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.0	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.9	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.3	GO:0060346	bone trabecula formation(GO:0060346)
0.0	0.1	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.0	0.3	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.2	GO:0060352	cell adhesion molecule production(GO:0060352)
0.0	0.2	GO:1903012	positive regulation of bone development(GO:1903012)
0.0	0.1	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.1	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.2	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.2	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.3	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.2	GO:0070269	pyroptosis(GO:0070269)
0.0	0.2	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:1903671	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
0.0	0.2	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.0	0.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.4	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0035739	CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.6	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.2	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.5	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.0	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.0	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.5	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.0	GO:0030953	astral microtubule organization(GO:0030953)
0.0	0.1	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.1	GO:0050904	diapedesis(GO:0050904)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.1	GO:0071888	macrophage apoptotic process(GO:0071888) regulation of macrophage apoptotic process(GO:2000109)
0.0	0.0	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.2	GO:0036035	osteoclast development(GO:0036035)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.0	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
0.0	0.0	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0051464	positive regulation of cortisol secretion(GO:0051464)
0.0	0.2	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.0	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.0	0.1	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
0.0	0.3	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0052428	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.3	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.0	0.0	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.0	GO:2000855	mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0	0.1	GO:0071435	potassium ion export(GO:0071435)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.1	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.0	GO:0060416	response to growth hormone(GO:0060416)
0.0	0.7	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.8	GO:0006940	regulation of smooth muscle contraction(GO:0006940)
0.0	0.3	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.0	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.1	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.0	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.1	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.1	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.1	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
0.0	0.0	GO:0060931	sinoatrial node cell development(GO:0060931)
0.0	0.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.4	GO:1901099	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:1905048	regulation of metallopeptidase activity(GO:1905048)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.2	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.0	GO:0060268	negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.0	0.2	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.0	GO:0003266	cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264) regulation of secondary heart field cardioblast proliferation(GO:0003266)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.0	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0	0.1	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.0	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.0	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	0.0	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.0	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.2	GO:0051444	negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0	0.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.1	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.1	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.2	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.6	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.0	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.0	GO:0048880	sensory system development(GO:0048880)
0.0	0.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.0	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.0	0.1	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0	0.0	GO:0032202	telomere assembly(GO:0032202)
0.0	0.1	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.0	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.4	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.2	GO:0006301	postreplication repair(GO:0006301)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.0	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.0	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.0	0.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.2	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.1	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.1	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.0	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0006825	copper ion transport(GO:0006825)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0021778	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934)
0.0	0.0	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.1	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.0	0.0	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.2	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.0	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.0	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0	0.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.0	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.0	0.3	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.0	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.2	GO:0032611	interleukin-1 beta production(GO:0032611)
0.0	0.0	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.0	0.0	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0	0.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.7	GO:0006941	striated muscle contraction(GO:0006941)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.0	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.0	GO:0015817	histidine transport(GO:0015817)
0.0	0.0	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0	0.1	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.0	0.0	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0097512	cardiac myofibril(GO:0097512)
0.3	0.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.3	1.3	GO:0005927	muscle tendon junction(GO:0005927)
0.2	0.7	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	0.6	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2	0.8	GO:0030478	actin cap(GO:0030478)
0.2	0.5	GO:0042585	germinal vesicle(GO:0042585)
0.1	0.6	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.8	GO:0030314	junctional membrane complex(GO:0030314)
0.1	0.6	GO:0031415	NatA complex(GO:0031415)
0.1	0.9	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.6	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.8	GO:0036157	outer dynein arm(GO:0036157)
0.1	0.9	GO:0020003	symbiont-containing vacuole(GO:0020003)
0.1	0.7	GO:0005861	troponin complex(GO:0005861)
0.1	0.4	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.4	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.9	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	1.3	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.5	GO:0042382	paraspeckles(GO:0042382)
0.1	0.3	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.4	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.5	GO:0097542	ciliary tip(GO:0097542)
0.1	0.4	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.2	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.2	GO:0033269	internode region of axon(GO:0033269)
0.1	0.5	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.7	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.2	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0097450	astrocyte end-foot(GO:0097450)
0.0	0.1	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	0.4	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.4	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:1990745	EARP complex(GO:1990745)
0.0	1.5	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	1.9	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	2.0	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0000235	astral microtubule(GO:0000235)
0.0	1.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.0	GO:0005914	spot adherens junction(GO:0005914)
0.0	0.2	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.7	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	1.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	1.0	GO:0005902	microvillus(GO:0005902)
0.0	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	1.2	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.4	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.7	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.4	GO:0051233	spindle midzone(GO:0051233)
0.0	0.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0019815	B cell receptor complex(GO:0019815)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.3	GO:0030894	replisome(GO:0030894)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.9	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	1.0	GO:0005604	basement membrane(GO:0005604)
0.0	0.0	GO:0005767	secondary lysosome(GO:0005767)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	3.3	GO:0045177	apical part of cell(GO:0045177)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.4	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0005903	brush border(GO:0005903)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.9	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.0	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.0	GO:0070938	contractile ring(GO:0070938)
0.0	1.6	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.0	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.0	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.2	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.5	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.2	GO:0000786	nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.5	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.3	0.8	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3	1.1	GO:0004046	aminoacylase activity(GO:0004046)
0.3	0.8	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.2	0.7	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2	0.7	GO:0018595	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.2	1.2	GO:0004064	arylesterase activity(GO:0004064)
0.2	0.7	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2	0.5	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.2	1.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2	1.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.2	0.6	GO:0031014	troponin T binding(GO:0031014)
0.2	0.6	GO:0032564	dATP binding(GO:0032564)
0.1	1.9	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.6	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.4	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.1	0.4	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.1	0.8	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1	0.6	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1	0.6	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.4	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.1	0.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.6	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.5	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.1	0.7	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.3	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.3	GO:0035877	death effector domain binding(GO:0035877)
0.1	1.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	1.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.7	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.3	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1	0.4	GO:0009374	biotin binding(GO:0009374)
0.1	0.4	GO:0005534	galactose binding(GO:0005534)
0.1	0.9	GO:0005523	tropomyosin binding(GO:0005523)
0.1	1.0	GO:0017166	vinculin binding(GO:0017166)
0.1	1.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	0.2	GO:0070698	type I activin receptor binding(GO:0070698)
0.1	0.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.3	GO:0015265	urea channel activity(GO:0015265)
0.1	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	1.3	GO:0035173	histone kinase activity(GO:0035173)
0.1	0.3	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	0.3	GO:0031720	haptoglobin binding(GO:0031720)
0.1	0.3	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.2	GO:0070573	metallodipeptidase activity(GO:0070573)
0.1	1.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.1	0.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	1.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.2	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.1	0.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.2	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.1	0.3	GO:0035473	lipase binding(GO:0035473)
0.1	0.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	1.1	GO:0005537	mannose binding(GO:0005537)
0.1	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.3	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.3	GO:0043910	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.4	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.3	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.6	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.3	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.4	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.6	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.3	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.8	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	1.9	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	1.0	GO:0045502	dynein binding(GO:0045502)
0.0	0.6	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.3	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.6	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	1.5	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.6	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.5	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.3	GO:0019825	oxygen binding(GO:0019825)
0.0	0.2	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.3	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0015181	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.1	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.1	GO:2001070	starch binding(GO:2001070)
0.0	0.1	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.6	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	1.3	GO:0051087	chaperone binding(GO:0051087)
0.0	0.0	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.4	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.6	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.4	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.0	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.0	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.6	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.3	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0034889	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	1.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.8	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0016631	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0	0.5	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.2	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0	0.0	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.5	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.1	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.0	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.0	0.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.2	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.0	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.0	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.0	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.3	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.0	GO:0032142	single guanine insertion binding(GO:0032142)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.0	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.1	GO:0031005	filamin binding(GO:0031005)
0.0	0.0	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0008828	thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0	0.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.0	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.5	GO:0005518	collagen binding(GO:0005518)
0.0	0.0	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	3.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	1.0	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	1.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.6	PID EPO PATHWAY	EPO signaling pathway
0.0	1.0	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.9	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.7	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.5	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.1	PID ATR PATHWAY	ATR signaling pathway
0.0	0.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	ST ADRENERGIC	Adrenergic Pathway
0.0	0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.5	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID AP1 PATHWAY	AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	1.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	1.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	0.2	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	2.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	0.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.0	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.1	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.6	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	1.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.5	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.0	0.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	1.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.5	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events

Results for Hsf1

Z-value: 0.84

Motif logo

Transcription factors associated with Hsf1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hsf1 motif across conditions

Conditions sorted by the z-value of the Hsf1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: