Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Insm1

Z-value: 0.93

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Transcription factors associated with Insm1

Gene Symbol Gene ID Gene Info
ENSMUSG00000068154.4 Insm1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Insm1chr2_146224758_14622490929120.2397710.681.8e-09Click!
Insm1chr2_146225143_14622564134710.2202060.675.6e-09Click!
Insm1chr2_146224129_14622428022830.2776620.676.1e-09Click!
Insm1chr2_146221972_1462236999140.5639830.651.5e-08Click!
Insm1chr2_146226178_14622644043880.2015180.531.2e-05Click!

Activity of the Insm1 motif across conditions

Conditions sorted by the z-value of the Insm1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_41070697_41071486 4.67 Gpr6
G protein-coupled receptor 6
1194
0.41
chr1_42697532_42698715 3.86 Pou3f3
POU domain, class 3, transcription factor 3
2355
0.2
chr11_118908287_118909561 3.18 Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
626
0.73
chr9_106147912_106149765 3.10 D030055H07Rik
RIKEN cDNA D030055H07 gene
151
0.9
chr8_123891512_123893657 2.88 Acta1
actin, alpha 1, skeletal muscle
2167
0.16
chr9_57941167_57941414 2.74 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
1177
0.43
chr7_79501250_79502506 2.70 Mir9-3hg
Mir9-3 host gene
1757
0.18
chr15_103026302_103028215 2.68 Hoxc4
homeobox C4
7137
0.09
chr13_34075859_34076222 2.59 Tubb2a
tubulin, beta 2A class IIA
1967
0.19
chr10_86491670_86492273 2.50 Syn3
synapsin III
74
0.96
chr2_52557337_52558561 2.49 Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
611
0.74
chr9_91378153_91379783 2.47 Zic4
zinc finger protein of the cerebellum 4
326
0.81
chr17_43954528_43954986 2.46 Rcan2
regulator of calcineurin 2
1506
0.53
chr2_178141581_178143125 2.40 Phactr3
phosphatase and actin regulator 3
420
0.88
chr4_106914283_106915196 2.26 Ssbp3
single-stranded DNA binding protein 3
2441
0.31
chr12_117153278_117156362 2.25 Gm10421
predicted gene 10421
3169
0.37
chr3_88206822_88208169 2.22 Gm3764
predicted gene 3764
183
0.86
chr3_45379351_45381850 2.20 Pcdh10
protocadherin 10
2033
0.25
chr5_111421306_111422790 2.11 Gm43119
predicted gene 43119
1541
0.35
chr6_107532409_107532560 2.04 Lrrn1
leucine rich repeat protein 1, neuronal
2716
0.32
chr6_91409540_91411888 2.03 Wnt7a
wingless-type MMTV integration site family, member 7A
649
0.42
chr10_80300884_80302968 2.03 Apc2
APC regulator of WNT signaling pathway 2
106
0.9
chr15_88561170_88561806 2.00 Zdhhc25
zinc finger, DHHC domain containing 25
38814
0.19
chr4_22479026_22480517 1.99 Pou3f2
POU domain, class 3, transcription factor 2
8595
0.17
chr5_111418246_111419747 1.98 Mn1
meningioma 1
1554
0.34
chr11_98962463_98964377 1.90 Rara
retinoic acid receptor, alpha
3008
0.14
chr19_6829828_6831569 1.89 Mir5046
microRNA 5046
754
0.39
chr6_105676979_105678296 1.89 Cntn4
contactin 4
23
0.52
chr7_51624664_51625766 1.85 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
67
0.98
chr4_49844475_49845850 1.76 Grin3a
glutamate receptor ionotropic, NMDA3A
387
0.91
chr12_85150310_85151505 1.75 Rps6kl1
ribosomal protein S6 kinase-like 1
329
0.81
chr7_51626624_51628140 1.70 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
2098
0.31
chrX_170674573_170675954 1.67 Asmt
acetylserotonin O-methyltransferase
2619
0.41
chr2_158606690_158608449 1.66 Gm14204
predicted gene 14204
3021
0.15
chr3_28265727_28265948 1.64 Tnik
TRAF2 and NCK interacting kinase
2194
0.33
chr2_152081612_152083149 1.63 Scrt2
scratch family zinc finger 2
851
0.52
chr10_85389057_85389718 1.60 Btbd11
BTB (POZ) domain containing 11
2560
0.31
chr5_9724633_9726223 1.60 Grm3
glutamate receptor, metabotropic 3
258
0.93
chr1_18057820_18058958 1.60 Gm45784
predicted gene 45784
120
0.8
chr1_98046701_98047306 1.56 B230216N24Rik
RIKEN cDNA B230216N24 gene
751
0.61
chr19_6418703_6419936 1.48 Nrxn2
neurexin II
554
0.44
chr1_168426195_168428871 1.48 Pbx1
pre B cell leukemia homeobox 1
3971
0.3
chr1_177446374_177448525 1.48 Zbtb18
zinc finger and BTB domain containing 18
1628
0.31
chr19_24134495_24135463 1.45 Tjp2
tight junction protein 2
8103
0.17
chr7_141428600_141429722 1.45 Cend1
cell cycle exit and neuronal differentiation 1
190
0.82
chr11_55607331_55608633 1.45 Glra1
glycine receptor, alpha 1 subunit
161
0.96
chr1_166255711_166256817 1.44 Ildr2
immunoglobulin-like domain containing receptor 2
2071
0.3
chr17_56241459_56242409 1.43 A230051N06Rik
RIKEN cDNA A230051N06 gene
218
0.81
chr4_125493964_125494986 1.39 Grik3
glutamate receptor, ionotropic, kainate 3
3775
0.23
chr9_43069102_43069597 1.37 Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
26717
0.17
chr17_43157421_43159105 1.36 E130008D07Rik
RIKEN cDNA E130008D07 gene
3
0.99
chr5_135248496_135249658 1.36 Fzd9
frizzled class receptor 9
2153
0.21
chr19_60146143_60147364 1.33 E330013P04Rik
RIKEN cDNA E330013P04 gene
2049
0.34
chr8_12399326_12400483 1.33 Gm25239
predicted gene, 25239
3501
0.16
chr5_30718180_30718893 1.33 Dpysl5
dihydropyrimidinase-like 5
6635
0.15
chr10_89256685_89257951 1.31 Ano4
anoctamin 4
18
0.99
chr4_148286849_148288201 1.31 Disp3
dispatched RND transporter family member 3
440
0.81
chr15_99579884_99580035 1.30 Aqp2
aquaporin 2
904
0.41
chr2_22626812_22627730 1.30 Gad2
glutamic acid decarboxylase 2
3967
0.16
chr9_91369028_91370469 1.29 Zic4
zinc finger protein of the cerebellum 4
250
0.86
chr16_72027587_72029370 1.27 Gm49667
predicted gene, 49667
149434
0.04
chr11_69558887_69560206 1.26 Efnb3
ephrin B3
659
0.46
chr15_98169300_98169725 1.26 Ccdc184
coiled-coil domain containing 184
2354
0.18
chr5_66675564_66677315 1.25 Uchl1os
ubiquitin carboxy-terminal hydrolase L1, opposite strand
59
0.69
chr6_89355842_89356077 1.24 Plxna1
plexin A1
1758
0.32
chr15_25756012_25756679 1.23 Myo10
myosin X
2420
0.34
chr3_156561493_156562639 1.23 Negr1
neuronal growth regulator 1
80
0.8
chr1_25832036_25832712 1.22 Gm9884
predicted gene 9884
1717
0.22
chr5_100908642_100908798 1.22 Gm36793
predicted gene, 36793
4987
0.17
chr2_136713069_136714459 1.22 Snap25
synaptosomal-associated protein 25
286
0.92
chr4_155409208_155409931 1.21 Cfap74
cilia and flagella associated protein 74
311
0.83
chr3_56181373_56181654 1.21 Nbea
neurobeachin
2188
0.32
chr7_25003389_25003696 1.20 Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
2353
0.17
chr9_26806442_26806962 1.19 Glb1l2
galactosidase, beta 1-like 2
234
0.93
chr17_35681826_35681977 1.19 Gtf2h4
general transcription factor II H, polypeptide 4
8162
0.08
chr11_118907285_118907593 1.19 Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
566
0.76
chr3_88210226_88210408 1.19 Gm3764
predicted gene 3764
845
0.35
chr6_128030323_128030501 1.18 Tspan9
tetraspanin 9
4180
0.22
chr9_106655308_106656548 1.18 Grm2
glutamate receptor, metabotropic 2
152
0.93
chr8_58911260_58911448 1.17 Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
222
0.7
chr9_87015230_87016430 1.16 Ripply2
ripply transcriptional repressor 2
194
0.94
chr11_88100783_88100934 1.15 Cuedc1
CUE domain containing 1
1568
0.32
chr15_68931535_68932379 1.14 Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
1889
0.38
chr6_83185720_83187846 1.14 Dctn1
dynactin 1
837
0.39
chr3_83127129_83128908 1.13 Dchs2
dachsous cadherin related 2
70
0.96
chr18_79023064_79023215 1.12 Setbp1
SET binding protein 1
86252
0.1
chr1_146494200_146495557 1.11 Gm29514
predicted gene 29514
73
0.56
chr13_21897738_21897959 1.11 Mir1983
microRNA 1983
799
0.35
chr10_3863416_3864702 1.10 Gm16149
predicted gene 16149
5548
0.21
chr5_120433178_120434996 1.09 Gm27199
predicted gene 27199
2320
0.19
chr5_27048872_27050274 1.08 Dpp6
dipeptidylpeptidase 6
180
0.97
chr14_14345697_14346878 1.08 Il3ra
interleukin 3 receptor, alpha chain
12
0.94
chr7_131966504_131967699 1.08 Gpr26
G protein-coupled receptor 26
641
0.75
chr2_17730363_17731639 1.08 Nebl
nebulette
42
0.98
chrX_140278669_140278820 1.08 Gm15046
predicted gene 15046
882
0.64
chr7_16135529_16135904 1.07 Slc8a2
solute carrier family 8 (sodium/calcium exchanger), member 2
5368
0.13
chr18_59176268_59176419 1.07 Chsy3
chondroitin sulfate synthase 3
693
0.81
chr13_63554202_63556305 1.06 Ptch1
patched 1
8562
0.14
chr9_52676918_52677560 1.06 AI593442
expressed sequence AI593442
2190
0.3
chr10_81024569_81025640 1.06 Gm16099
predicted gene 16099
21
0.8
chr18_60925301_60926809 1.06 Camk2a
calcium/calmodulin-dependent protein kinase II alpha
330
0.84
chr9_102545261_102545799 1.05 Gm25669
predicted gene, 25669
2236
0.18
chr2_70564530_70567543 1.05 Gad1
glutamate decarboxylase 1
341
0.83
chrX_99141766_99142562 1.05 Efnb1
ephrin B1
4033
0.29
chr1_34582116_34582629 1.05 1700101I19Rik
RIKEN cDNA 1700101I19 gene
2661
0.13
chr18_69518292_69518443 1.04 Tcf4
transcription factor 4
1112
0.61
chr14_64594009_64594633 1.04 Mir3078
microRNA 3078
3136
0.2
chr7_82871690_82872524 1.03 Mex3b
mex3 RNA binding family member B
4774
0.17
chr13_47042124_47042275 1.03 Tpmt
thiopurine methyltransferase
618
0.52
chr7_28303020_28303539 1.02 Dll3
delta like canonical Notch ligand 3
1041
0.28
chr13_83724319_83724624 1.01 C130071C03Rik
RIKEN cDNA C130071C03 gene
3090
0.17
chr7_130696527_130696728 1.00 Tacc2
transforming, acidic coiled-coil containing protein 2
3862
0.23
chr14_111676787_111676972 1.00 Slitrk5
SLIT and NTRK-like family, member 5
1030
0.58
chr9_46388989_46390269 0.99 Gm47141
predicted gene, 47141
7733
0.16
chr7_60938135_60938329 0.98 Gm44644
predicted gene 44644
15322
0.23
chr15_79328330_79328657 0.98 Pla2g6
phospholipase A2, group VI
103
0.94
chr8_81341679_81342941 0.97 Inpp4b
inositol polyphosphate-4-phosphatase, type II
246
0.94
chrX_5467696_5468887 0.97 Mycs
myc-like oncogene, s-myc protein
974
0.62
chr6_7556446_7556887 0.96 Tac1
tachykinin 1
575
0.78
chr18_86712592_86713744 0.96 Cbln2
cerebellin 2 precursor protein
120
0.98
chr10_79612978_79614016 0.95 C2cd4c
C2 calcium-dependent domain containing 4C
503
0.62
chr7_127823788_127824540 0.95 Stx4a
syntaxin 4A (placental)
130
0.74
chr11_55604582_55604890 0.94 Glra1
glycine receptor, alpha 1 subunit
2997
0.27
chr12_81332229_81333505 0.94 Slc8a3
solute carrier family 8 (sodium/calcium exchanger), member 3
92
0.97
chr13_102957440_102958679 0.93 Mast4
microtubule associated serine/threonine kinase family member 4
287
0.95
chr15_54745390_54746471 0.93 Ccn3
cellular communication network factor 3
228
0.95
chr7_79517534_79518210 0.93 Gm37608
predicted gene, 37608
990
0.32
chr9_124441736_124442440 0.93 Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
658
0.65
chr4_124881258_124882719 0.93 Epha10
Eph receptor A10
1089
0.34
chr7_137297687_137298458 0.93 Ebf3
early B cell factor 3
15844
0.18
chrX_98149736_98151206 0.92 Ar
androgen receptor
1702
0.52
chr14_67229549_67230710 0.91 Gm20675
predicted gene 20675
3000
0.21
chr16_35542503_35542768 0.91 Sema5b
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
1064
0.49
chr16_39109478_39110008 0.91 Gm36742
predicted gene, 36742
79163
0.1
chr11_95231710_95232418 0.91 Gm11515
predicted gene 11515
6432
0.15
chr11_120046502_120047174 0.90 Aatk
apoptosis-associated tyrosine kinase
232
0.86
chr7_70328144_70328411 0.89 Gm29683
predicted gene, 29683
9545
0.13
chr16_28564192_28565135 0.89 Fgf12
fibroblast growth factor 12
288
0.94
chr13_34128849_34129198 0.89 Tubb2b
tubulin, beta 2B class IIB
1331
0.28
chr9_96837919_96838070 0.89 Pxylp1
2-phosphoxylose phosphatase 1
16930
0.13
chr7_27339048_27339745 0.88 Ltbp4
latent transforming growth factor beta binding protein 4
1704
0.22
chr5_112575866_112576017 0.88 Sez6l
seizure related 6 homolog like
927
0.51
chr16_18129524_18129878 0.88 Rtn4r
reticulon 4 receptor
2059
0.22
chr15_78709935_78710827 0.88 Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
398
0.81
chr15_79161202_79161377 0.87 Sox10
SRY (sex determining region Y)-box 10
3185
0.12
chr8_83938585_83938736 0.87 Adgrl1
adhesion G protein-coupled receptor L1
1005
0.32
chr16_97167039_97167850 0.87 Dscam
DS cell adhesion molecule
3308
0.37
chrX_143930842_143933141 0.86 Dcx
doublecortin
1059
0.64
chr10_84437396_84437950 0.86 Nuak1
NUAK family, SNF1-like kinase, 1
2924
0.2
chr9_83803848_83804133 0.86 Elovl4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
2262
0.32
chr2_157431812_157432077 0.85 Src
Rous sarcoma oncogene
7552
0.19
chr9_108824114_108825614 0.85 Gm35025
predicted gene, 35025
3
0.87
chr3_17793835_17795104 0.85 Mir124-2hg
Mir124-2 host gene (non-protein coding)
427
0.75
chrX_105390628_105392456 0.85 5330434G04Rik
RIKEN cDNA 5330434G04 gene
212
0.93
chr14_21992049_21992761 0.85 C130012C08Rik
RIKEN cDNA C130012C08 gene
31
0.97
chrX_99140845_99141717 0.84 Efnb1
ephrin B1
3150
0.32
chr9_63144078_63146888 0.84 Skor1
SKI family transcriptional corepressor 1
1497
0.38
chr7_16611263_16612711 0.84 Gm29443
predicted gene 29443
1837
0.17
chr7_127017759_127019737 0.84 Prrt2
proline-rich transmembrane protein 2
847
0.23
chr15_95653733_95655035 0.84 Dbx2
developing brain homeobox 2
1576
0.4
chr15_99056560_99057587 0.83 Prph
peripherin
1103
0.3
chr7_44606065_44607042 0.81 Myh14
myosin, heavy polypeptide 14
7572
0.08
chr9_58135040_58135292 0.81 Stra6
stimulated by retinoic acid gene 6
356
0.8
chr17_45546681_45547495 0.81 Tmem151b
transmembrane protein 151B
2589
0.14
chr12_33927803_33927954 0.80 Ferd3l
Fer3 like bHLH transcription factor
547
0.47
chr6_47879804_47880414 0.79 Zfp282
zinc finger protein 282
2453
0.19
chr11_98797866_98798017 0.79 Msl1
male specific lethal 1
713
0.49
chr17_15207684_15208974 0.79 Gm5091
predicted gene 5091
32454
0.15
chr11_97572309_97572897 0.78 Srcin1
SRC kinase signaling inhibitor 1
1326
0.33
chr11_96296491_96297669 0.78 Hoxb6
homeobox B6
2091
0.12
chr15_82982691_82984011 0.78 Gm29019
predicted gene 29019
4361
0.15
chr7_4920681_4922210 0.78 Nat14
N-acetyltransferase 14
583
0.48
chr10_64085785_64086050 0.78 Lrrtm3
leucine rich repeat transmembrane neuronal 3
4330
0.36
chr7_79498955_79500626 0.78 Mir9-3hg
Mir9-3 host gene
236
0.84
chr2_158611997_158612747 0.78 Gm14205
predicted gene 14205
552
0.57
chr19_46034115_46034266 0.78 Ldb1
LIM domain binding 1
688
0.58
chr8_84934277_84934726 0.77 Mast1
microtubule associated serine/threonine kinase 1
2843
0.09
chr17_72602980_72604745 0.77 Alk
anaplastic lymphoma kinase
35
0.99
chr11_103773284_103774731 0.77 Wnt3
wingless-type MMTV integration site family, member 3
143
0.95
chr12_83044808_83045343 0.77 Rgs6
regulator of G-protein signaling 6
1915
0.37
chr2_164967685_164969910 0.77 Slc12a5
solute carrier family 12, member 5
516
0.7
chr6_124915605_124915906 0.76 Ptms
parathymosin
226
0.79
chr15_84662838_84664037 0.76 Prr5
proline rich 5 (renal)
6183
0.21
chr7_24508610_24508761 0.76 Zfp428
zinc finger protein 428
1555
0.19
chr4_45824847_45825701 0.76 Igfbpl1
insulin-like growth factor binding protein-like 1
1649
0.31
chr1_135583494_135584229 0.76 Gm4793
predicted gene 4793
912
0.48
chr7_126952524_126952951 0.76 Sez6l2
seizure related 6 homolog like 2
1130
0.2
chr8_124433385_124434495 0.76 Pgbd5
piggyBac transposable element derived 5
4
0.98
chr17_17830776_17830949 0.76 Spaca6
sperm acrosome associated 6
31
0.45
chr7_25359927_25360078 0.76 Cnfn
cornifelin
9701
0.09
chr2_154557851_154559156 0.76 Necab3
N-terminal EF-hand calcium binding protein 3
341
0.79
chr7_78882466_78883900 0.76 Mir7-2
microRNA 7-2
5094
0.13
chr2_109693096_109694906 0.76 Bdnf
brain derived neurotrophic factor
408
0.85
chr5_136881600_136883223 0.75 Col26a1
collagen, type XXVI, alpha 1
332
0.82
chr11_115364077_115364228 0.75 Hid1
HID1 domain containing
3457
0.11
chr4_127986376_127987202 0.75 Csmd2
CUB and Sushi multiple domains 2
1068
0.6
chr6_93911862_93913573 0.74 Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
213
0.95
chr9_91366433_91367646 0.74 Zic1
zinc finger protein of the cerebellum 1
1229
0.26
chr9_16499783_16502054 0.74 Fat3
FAT atypical cadherin 3
367
0.92
chr6_125111760_125111911 0.74 Chd4
chromodomain helicase DNA binding protein 4
1706
0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Insm1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.4 1.1 GO:0001757 somite specification(GO:0001757)
0.4 1.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.3 1.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.3 0.9 GO:0072240 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.3 1.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.3 1.5 GO:0061038 uterus morphogenesis(GO:0061038)
0.3 0.9 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 0.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.2 GO:0007412 axon target recognition(GO:0007412)
0.3 1.1 GO:0061643 chemorepulsion of axon(GO:0061643)
0.3 0.5 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 1.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.3 2.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 0.8 GO:0043309 regulation of eosinophil degranulation(GO:0043309)
0.3 0.8 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.3 0.8 GO:0061144 alveolar secondary septum development(GO:0061144)
0.3 0.8 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 0.5 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 1.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.2 0.6 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.2 2.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.2 GO:0030916 otic vesicle formation(GO:0030916)
0.2 0.6 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.2 0.4 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.2 0.6 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.2 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.5 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 0.6 GO:0072553 terminal button organization(GO:0072553)
0.2 0.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 0.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.2 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.7 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.6 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.5 GO:1903818 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.9 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.2 GO:1903011 negative regulation of bone development(GO:1903011)
0.1 1.9 GO:0001504 neurotransmitter uptake(GO:0001504)
0.1 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.5 GO:0046959 habituation(GO:0046959)
0.1 0.4 GO:0008355 olfactory learning(GO:0008355)
0.1 0.4 GO:0002930 trabecular meshwork development(GO:0002930)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 3.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 1.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.6 GO:0098598 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.1 0.3 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.3 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
0.1 0.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.1 GO:1902302 regulation of potassium ion export(GO:1902302)
0.1 0.4 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.1 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.1 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.2 GO:0097476 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.1 0.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.4 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.1 0.3 GO:0042851 L-alanine metabolic process(GO:0042851)
0.1 0.2 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.1 0.2 GO:2000599 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1 1.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.2 GO:0021570 rhombomere 4 development(GO:0021570)
0.1 0.7 GO:0045176 apical protein localization(GO:0045176)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.2 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.2 GO:0060618 nipple development(GO:0060618)
0.1 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.2 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.9 GO:0070977 bone maturation(GO:0070977)
0.1 0.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 2.3 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.1 0.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.1 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.2 GO:1900238 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.1 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.6 GO:0021756 striatum development(GO:0021756)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.2 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.1 0.6 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.0 GO:0010842 retina layer formation(GO:0010842)
0.1 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:0001975 response to amphetamine(GO:0001975)
0.1 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.4 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.2 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.4 GO:0046541 saliva secretion(GO:0046541)
0.1 0.2 GO:0015879 carnitine transport(GO:0015879)
0.1 0.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.5 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.2 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.1 0.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.1 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.1 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.1 2.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.1 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.0 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 3.7 GO:0099531 presynaptic process involved in chemical synaptic transmission(GO:0099531)
0.1 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0072051 juxtaglomerular apparatus development(GO:0072051)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.8 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:1902855 regulation of nonmotile primary cilium assembly(GO:1902855)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.1 GO:0010288 response to lead ion(GO:0010288)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.0 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.0 0.1 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 1.1 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 1.0 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.6 GO:0051904 establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402) pigment granule transport(GO:0051904) establishment of pigment granule localization(GO:0051905)
0.0 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.3 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.4 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0061156 pulmonary artery morphogenesis(GO:0061156)
0.0 0.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.0 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.0 GO:1904938 dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.0 0.9 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.2 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 2.0 GO:0050905 neuromuscular process(GO:0050905)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.0 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.0 0.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.0 0.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.0 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.0 0.2 GO:0030432 peristalsis(GO:0030432)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.4 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.0 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:2000391 regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.4 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.0 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.2 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0072143 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) pericyte cell differentiation(GO:1904238)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:1990000 amyloid fibril formation(GO:1990000)
0.0 0.1 GO:0071865 regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0071435 potassium ion export(GO:0071435)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.0 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.0 0.1 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0 0.4 GO:0021766 hippocampus development(GO:0021766)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0070662 mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.0 GO:0071724 response to diacyl bacterial lipopeptide(GO:0071724) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to diacyl bacterial lipopeptide(GO:0071726) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.0 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:1903859 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.0 GO:0043307 eosinophil activation(GO:0043307)
0.0 0.2 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.0 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.0 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430) regulation of tau-protein kinase activity(GO:1902947) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:1903660 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.3 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.0 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0032095 regulation of response to food(GO:0032095)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0048819 regulation of hair follicle maturation(GO:0048819)
0.0 0.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 1.1 GO:0007411 axon guidance(GO:0007411)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0051645 Golgi localization(GO:0051645)
0.0 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.0 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.0 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.0 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0 0.0 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.7 GO:0007631 feeding behavior(GO:0007631)
0.0 0.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.0 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.2 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.0 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.0 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.0 GO:1904526 regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.0 0.2 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0042044 fluid transport(GO:0042044)
0.0 0.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0 0.0 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.1 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0035728 response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.0 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.0 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.1 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.0 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.0 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3 1.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 0.8 GO:0000322 storage vacuole(GO:0000322)
0.2 4.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 6.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 1.6 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 0.3 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.1 1.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.3 GO:0044299 C-fiber(GO:0044299)
0.1 0.1 GO:0097513 myosin II filament(GO:0097513)
0.1 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 6.4 GO:0043204 perikaryon(GO:0043204)
0.1 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.3 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.6 GO:0032433 filopodium tip(GO:0032433)
0.1 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.8 GO:0031231 intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 4.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0097060 synaptic membrane(GO:0097060)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576)
0.0 0.1 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 0.0 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 2.5 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 3.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.0 GO:0042567 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.0 GO:0000444 MIS12/MIND type complex(GO:0000444)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.4 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 2.9 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.4 1.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 2.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.3 1.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 2.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.2 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 2.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 1.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.2 GO:0086056 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 0.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 1.7 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.1 1.1 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0038064 collagen receptor activity(GO:0038064)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.1 1.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0008430 selenium binding(GO:0008430)
0.1 0.8 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.1 0.3 GO:0052796 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.1 GO:0030507 spectrin binding(GO:0030507)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 0.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0016015 morphogen activity(GO:0016015)
0.1 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 1.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.1 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.0 GO:0016751 S-succinyltransferase activity(GO:0016751)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.6 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0034889 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0008147 structural constituent of bone(GO:0008147)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0019976 interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0015189 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.4 GO:0045502 dynein binding(GO:0045502)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.0 GO:0038100 nodal binding(GO:0038100)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.2 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.0 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.0 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.0 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.0 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.7 GO:0019838 growth factor binding(GO:0019838)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0016415 octanoyltransferase activity(GO:0016415)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 2.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.2 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 2.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.0 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway