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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Irf3

Z-value: 1.69

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Transcription factors associated with Irf3

Gene Symbol	Gene ID	Gene Info
Irf3 Ensembl NCBI MGI UniProt	ENSMUSG00000003184.8	interferon regulatory factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_45003548_45003726	Irf3	2250	0.095857	-0.46	2.3e-04	Click!
chr7_45004199_45004870	Irf3	3147	0.075572	-0.42	7.5e-04	Click!
chr7_45006204_45006534	Irf3	4982	0.061856	-0.40	1.5e-03	Click!
chr7_45005376_45006035	Irf3	4318	0.065028	-0.39	2.1e-03	Click!
chr7_45001404_45002263	Irf3	446	0.541911	-0.37	3.7e-03	Click!

Activity of the Irf3 motif across conditions

Conditions sorted by the z-value of the Irf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_86581322_86581839	8.23	Mir21a	microRNA 21a	2578	0.21
chr4_11146992_11147797	6.62	Gm11830	predicted gene 11830	2684	0.17
chr5_120812597_120813108	6.37	Oas1b	2'-5' oligoadenylate synthetase 1B	214	0.61
chr19_31868788_31869365	5.82	A1cf	APOBEC1 complementation factor	295	0.93
chr2_18821363_18822378	5.76	Carlr	cardiac and apoptosis-related long non-coding RNA	20052	0.17
chr16_84621188_84621719	5.73	Gm2477	predicted gene 2477	20247	0.15
chr11_119394258_119394694	5.58	Rnf213	ring finger protein 213	1376	0.33
chr13_59820073_59820550	5.53	Tut7	terminal uridylyl transferase 7	2277	0.17
chr7_78913499_78914279	5.52	Isg20	interferon-stimulated protein	92	0.95
chr15_81199540_81199753	5.29	4930483J18Rik	RIKEN cDNA 4930483J18 gene	8793	0.13
chr5_92353176_92354033	5.23	Cxcl10	chemokine (C-X-C motif) ligand 10	4715	0.11
chr7_104287615_104288174	5.12	Trim5	tripartite motif-containing 5	200	0.86
chr13_40859651_40861342	4.93	Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	742	0.5
chr14_99772626_99773392	4.90	Gm22970	predicted gene, 22970	799	0.67
chr17_36020346_36021134	4.81	H2-T24	histocompatibility 2, T region locus 24	180	0.83
chr4_86885709_86886839	4.78	Acer2	alkaline ceramidase 2	11860	0.21
chr10_59636764_59637076	4.78	Mcu	mitochondrial calcium uniporter	20228	0.17
chr12_70136349_70136831	4.68	Abhd12b	abhydrolase domain containing 12B	17552	0.14
chr13_94382387_94382639	4.66	Ap3b1	adaptor-related protein complex 3, beta 1 subunit	23553	0.16
chr2_79087179_79088090	4.64	Gm14469	predicted gene 14469	48900	0.14
chr11_20132956_20133378	4.39	Gm12030	predicted gene 12030	9401	0.16
chr11_58214604_58215588	4.38	Irgm2	immunity-related GTPase family M member 2	68	0.95
chr3_142496513_142497790	4.25	Gbp5	guanylate binding protein 5	209	0.93
chr1_66838249_66838716	4.24	Gm15793	predicted gene 15793	11120	0.08
chr12_111514659_111515318	4.22	Gm40578	predicted gene, 40578	14148	0.1
chr9_84107007_84107680	4.20	Bckdhb	branched chain ketoacid dehydrogenase E1, beta polypeptide	164	0.97
chr3_127893429_127894301	4.11	Fam241a	family with sequence similarity 241, member A	2423	0.2
chr19_41345332_41345831	4.06	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	39515	0.17
chr4_134093888_134094276	4.00	Cd52	CD52 antigen	956	0.38
chr7_75612178_75613652	3.93	Akap13	A kinase (PRKA) anchor protein 13	631	0.75
chr5_120906763_120907625	3.87	Oas1a	2'-5' oligoadenylate synthetase 1A	327	0.8
chr16_97534630_97535746	3.87	Mx2	MX dynamin-like GTPase 2	120	0.95
chr9_20868528_20869547	3.85	Shfl	shiftless antiviral inhibitor of ribosomal frameshifting	240	0.82
chr1_176836732_176837286	3.85	Gm38158	predicted gene, 38158	1285	0.31
chr12_55465326_55465841	3.79	Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	26227	0.14
chr6_129450832_129451818	3.69	Clec1a	C-type lectin domain family 1, member a	510	0.65
chr3_151749374_151749990	3.68	Ifi44	interferon-induced protein 44	200	0.95
chr2_44988425_44989191	3.65	Zeb2	zinc finger E-box binding homeobox 2	34107	0.17
chr13_37853570_37853733	3.61	Rreb1	ras responsive element binding protein 1	4283	0.24
chr10_44003353_44004622	3.57	Gm10812	predicted gene 10812	167	0.74
chr11_21549928_21550553	3.52	Mdh1	malate dehydrogenase 1, NAD (soluble)	9489	0.14
chr7_102564580_102565487	3.51	Trim21	tripartite motif-containing 21	412	0.62
chr8_72303671_72303933	3.49	Gm10282	predicted pseudogene 10282	1458	0.28
chr10_88336673_88337098	3.48	Dram1	DNA-damage regulated autophagy modulator 1	20111	0.14
chr19_35126831_35127081	3.48	Gm50140	predicted gene, 50140	2572	0.32
chr11_72301272_72302549	3.43	Xaf1	XIAP associated factor 1	245	0.87
chr8_122429671_122429928	3.41	Cyba	cytochrome b-245, alpha polypeptide	3106	0.11
chr19_29940390_29940617	3.37	Il33	interleukin 33	5287	0.21
chr4_135313499_135314239	3.37	Gm12982	predicted gene 12982	5899	0.12
chr1_138517267_138517596	3.31	Gm28501	predicted gene 28501	1816	0.36
chr6_57582472_57582776	3.29	Herc6	hect domain and RLD 6	1616	0.33
chr14_64501457_64502171	3.24	Gm47202	predicted gene, 47202	35724	0.15
chr16_55816801_55817114	3.22	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta	1558	0.38
chr15_76118017_76119354	3.20	Eppk1	epiplakin 1	1510	0.2
chr11_95339521_95340359	3.20	Fam117a	family with sequence similarity 117, member A	7	0.96
chr6_39380969_39382023	3.14	Rab19	RAB19, member RAS oncogene family	321	0.84
chr6_134932752_134933213	3.14	Gm44238	predicted gene, 44238	2870	0.15
chr2_101733066_101733288	3.14	Traf6	TNF receptor-associated factor 6	48962	0.13
chr2_62645458_62646847	3.13	Ifih1	interferon induced with helicase C domain 1	1	0.98
chr9_92265520_92266260	3.11	Plscr1	phospholipid scramblase 1	405	0.75
chr4_156200257_156201200	3.11	Isg15	ISG15 ubiquitin-like modifier	68	0.93
chr4_102573848_102574668	3.11	Pde4b	phosphodiesterase 4B, cAMP specific	4163	0.35
chr18_32559244_32560302	3.10	Gypc	glycophorin C	207	0.95
chr18_73541549_73542304	3.07	n-R5-8s1	nuclear encoded rRNA 5.8S 1	8376	0.22
chr1_180261995_180262146	3.06	Psen2	presenilin 2	1368	0.35
chr12_103656514_103657055	3.06	Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	318	0.81
chr12_40018053_40018384	2.98	Arl4a	ADP-ribosylation factor-like 4A	3734	0.23
chr5_120887135_120887643	2.97	Oas1g	2'-5' oligoadenylate synthetase 1G	193	0.89
chr11_49081444_49081768	2.91	Ifi47	interferon gamma inducible protein 47	5019	0.1
chrX_94033102_94033396	2.89	Gm14798	predicted gene 14798	4395	0.18
chr5_114897030_114897905	2.89	Oasl2	2'-5' oligoadenylate synthetase-like 2	65	0.94
chr5_88981527_88982249	2.87	Slc4a4	solute carrier family 4 (anion exchanger), member 4	46078	0.17
chr17_36023604_36024247	2.87	H2-T24	histocompatibility 2, T region locus 24	3365	0.08
chr6_87531320_87531883	2.86	Arhgap25	Rho GTPase activating protein 25	1634	0.27
chr13_48977850_48978331	2.85	Fam120a	family with sequence similarity 120, member A	10073	0.24
chr16_78540388_78540947	2.83	D16Ertd472e	DNA segment, Chr 16, ERATO Doi 472, expressed	19577	0.16
chr1_105971547_105972390	2.81	Gm18801	predicted gene, 18801	15658	0.14
chr13_45871849_45872363	2.77	Atxn1	ataxin 1	182	0.96
chr2_38997767_38998606	2.77	Gm13496	predicted gene 13496	72	0.57
chr9_45417234_45417420	2.73	Gm48135	predicted gene, 48135	3237	0.16
chr12_11203931_11204342	2.73	9530020I12Rik	RIKEN cDNA 9530020I12 gene	245	0.9
chr5_101239366_101239752	2.72	Cycs-ps2	cytochrome c, pseudogene 2	66019	0.13
chr2_170153321_170154276	2.72	Zfp217	zinc finger protein 217	5695	0.31
chr7_104352827_104353391	2.71	Trim12c	tripartite motif-containing 12C	229	0.84
chr17_33919393_33920922	2.70	Gm19412	predicted gene, 19412	132	0.67
chr9_58249301_58249714	2.69	Pml	promyelocytic leukemia	116	0.94
chr19_34640515_34641380	2.69	Ifit1	interferon-induced protein with tetratricopeptide repeats 1	76	0.67
chr3_142619966_142621017	2.67	Gbp2	guanylate binding protein 2	111	0.95
chr12_99406813_99407850	2.62	Foxn3	forkhead box N3	5274	0.18
chr6_126701984_126702357	2.61	Gm26673	predicted gene, 26673	16514	0.17
chr6_6004743_6005171	2.58	Dync1i1	dynein cytoplasmic 1 intermediate chain 1	1109	0.59
chr17_29493756_29495031	2.57	Pim1	proviral integration site 1	986	0.37
chr6_143750987_143751675	2.56	1700060C16Rik	RIKEN cDNA 1700060C16 gene	100043	0.08
chr9_66305145_66305804	2.56	Dapk2	death-associated protein kinase 2	37100	0.14
chr5_20944999_20945510	2.54	Rsbn1l	round spermatid basic protein 1-like	250	0.91
chr4_59546414_59547011	2.49	Ptbp3	polypyrimidine tract binding protein 3	2025	0.25
chr4_86875543_86876182	2.48	Acer2	alkaline ceramidase 2	1448	0.44
chr8_71536912_71538170	2.48	Bst2	bone marrow stromal cell antigen 2	85	0.92
chr15_4817024_4817255	2.46	Gm49073	predicted gene, 49073	6528	0.2
chr10_120363079_120363749	2.45	1700006J14Rik	RIKEN cDNA 1700006J14 gene	743	0.64
chr9_96713030_96713604	2.44	Zbtb38	zinc finger and BTB domain containing 38	6248	0.17
chr18_62168994_62169415	2.44	Adrb2	adrenergic receptor, beta 2	10755	0.19
chr6_97222827_97223144	2.44	Arl6ip5	ADP-ribosylation factor-like 6 interacting protein 5	12296	0.14
chr13_120096056_120097072	2.43	Gm21378	predicted gene, 21378	3768	0.15
chr18_78805197_78805419	2.42	Gm23895	predicted gene, 23895	157180	0.04
chr17_27342483_27343284	2.41	Gm10505	predicted gene 10505	421	0.67
chr6_67170260_67170833	2.41	A430010J10Rik	RIKEN cDNA A430010J10 gene	5343	0.17
chr13_119965491_119966496	2.40	Gm20784	predicted gene, 20784	3749	0.13
chr2_74678970_74680401	2.39	Hoxd11	homeobox D11	128	0.86
chr10_51405160_51405552	2.39	Gm46189	predicted gene, 46189	50624	0.11
chr11_83039798_83040490	2.39	Slfn10-ps	schlafen 10, pseudogene	102	0.91
chr17_34197631_34198714	2.38	Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	198	0.82
chr2_11192452_11193359	2.37	Gm37520	predicted gene, 37520	407	0.78
chr2_49771169_49771384	2.36	Lypd6b	LY6/PLAUR domain containing 6B	16412	0.19
chr5_36726034_36726843	2.36	Gm43701	predicted gene 43701	22180	0.11
chr7_90060194_90061467	2.34	Gm44861	predicted gene 44861	18133	0.12
chr6_34862829_34863673	2.29	Tmem140	transmembrane protein 140	11	0.96
chr2_174748654_174748982	2.29	Edn3	endothelin 3	11801	0.22
chr12_114378743_114379451	2.29	Ighv1-1	immunoglobulin heavy variable V1-1	27102	0.1
chr15_79693581_79694713	2.29	Gtpbp1	GTP binding protein 1	33	0.94
chr18_81426872_81427316	2.28	Gm30288	predicted gene, 30288	26878	0.21
chr6_30508580_30508840	2.25	Tmem209	transmembrane protein 209	994	0.35
chr10_62500909_62501268	2.24	Srgn	serglycin	6667	0.14
chr12_117545618_117545769	2.23	Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5	11805	0.22
chr11_102207669_102208475	2.23	Hdac5	histone deacetylase 5	7256	0.09
chr11_22871567_22872514	2.22	Gm24917	predicted gene, 24917	3139	0.16
chr8_116581220_116581574	2.21	Dynlrb2	dynein light chain roadblock-type 2	76382	0.1
chr1_193152798_193154089	2.21	Irf6	interferon regulatory factor 6	289	0.85
chr3_86758659_86759213	2.19	Gm37876	predicted gene, 37876	19717	0.19
chr11_117598702_117599975	2.19	2900041M22Rik	RIKEN cDNA 2900041M22 gene	11909	0.18
chr17_46162527_46163464	2.19	Gtpbp2	GTP binding protein 2	38	0.95
chr15_103250315_103251530	2.17	Nfe2	nuclear factor, erythroid derived 2	543	0.62
chr2_31143765_31144353	2.15	Fnbp1	formin binding protein 1	2051	0.25
chr18_21821900_21822125	2.14	Klhl14	kelch-like 14	167294	0.04
chr2_122164344_122164495	2.13	Trim69	tripartite motif-containing 69	3617	0.14
chr1_156037391_156037734	2.12	Tor1aip1	torsin A interacting protein 1	1082	0.37
chr6_34317495_34318174	2.10	Akr1b3	aldo-keto reductase family 1, member B3 (aldose reductase)	356	0.85
chr18_56756025_56756589	2.07	Gm15345	predicted gene 15345	13410	0.18
chr19_21714352_21714509	2.05	Gm50129	predicted gene, 50129	14840	0.19
chr11_119392783_119393622	2.05	Rnf213	ring finger protein 213	102	0.95
chr2_52377779_52377938	2.05	Neb	nebulin	616	0.68
chr3_105808615_105808957	2.04	Gm5547	predicted gene 5547	6754	0.11
chr12_35038598_35039444	2.03	Snx13	sorting nexin 13	8165	0.2
chr4_154926952_154928851	2.03	Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	176	0.92
chr15_3274516_3274905	2.02	Selenop	selenoprotein P	2625	0.3
chr12_63552794_63553211	2.02	Gm48417	predicted gene, 48417	18861	0.25
chr3_148998731_148998918	2.01	Gm43572	predicted gene 43572	6672	0.18
chr2_73484519_73485212	1.99	Wipf1	WAS/WASL interacting protein family, member 1	898	0.55
chr12_55491283_55491469	1.99	Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	434	0.82
chr15_102976255_102978005	1.96	Hoxc9	homeobox C9	98	0.92
chr2_118599857_118600417	1.96	Bub1b	BUB1B, mitotic checkpoint serine/threonine kinase	19	0.97
chr2_157131218_157131461	1.95	Samhd1	SAM domain and HD domain, 1	1282	0.39
chr15_97110664_97111016	1.95	Slc38a4	solute carrier family 38, member 4	54884	0.13
chr15_103305396_103305995	1.94	Gm49482	predicted gene, 49482	4630	0.11
chr3_97931938_97932089	1.93	Gm5544	predicted gene 5544	1840	0.31
chr1_161748349_161748500	1.93	Gm5049	predicted gene 5049	2368	0.23
chr4_33245981_33246490	1.92	Pnrc1	proline-rich nuclear receptor coactivator 1	1340	0.4
chr6_57822563_57823744	1.91	Vopp1	vesicular, overexpressed in cancer, prosurvival protein 1	1487	0.3
chr3_127123282_127124895	1.90	Ank2	ankyrin 2, brain	774	0.59
chr7_127992791_127993997	1.90	Gm45205	predicted gene 45205	125	0.49
chr11_95896737_95897369	1.89	B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	17838	0.09
chr8_34158216_34158638	1.89	Saraf	store-operated calcium entry-associated regulatory factor	54	0.95
chr17_36189137_36189654	1.88	H2-T3	histocompatibility 2, T region locus 3	727	0.28
chr4_56221989_56222579	1.87	2310081O03Rik	RIKEN cDNA 2310081O03 gene	2237	0.41
chr16_23609555_23610281	1.87	Rtp4	receptor transporter protein 4	1	0.98
chr8_46546525_46546715	1.86	Cenpu	centromere protein U	5408	0.17
chr3_60408400_60409132	1.84	Mbnl1	muscleblind like splicing factor 1	64064	0.12
chr5_100567625_100568203	1.84	Plac8	placenta-specific 8	4278	0.16
chr3_90537286_90538406	1.83	S100a16	S100 calcium binding protein A16	521	0.54
chr19_30030495_30031760	1.83	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	538	0.78
chr8_111630457_111630683	1.83	Ldhd	lactate dehydrogenase D	196	0.93
chr17_57234704_57235202	1.82	C3	complement component 3	6817	0.11
chr2_11375041_11375228	1.80	Gm37730	predicted gene, 37730	7683	0.1
chr14_103033283_103033652	1.80	4933432I03Rik	RIKEN cDNA 4933432I03 gene	336	0.83
chr6_57580700_57581747	1.80	Herc6	hect domain and RLD 6	215	0.92
chrX_145516085_145516305	1.80	Amot	angiomotin	11014	0.26
chr13_23709997_23710919	1.79	Hfe	homeostatic iron regulator	256	0.71
chr3_95906616_95907337	1.78	Car14	carbonic anhydrase 14	2285	0.13
chr17_49436615_49437040	1.77	Mocs1	molybdenum cofactor synthesis 1	3631	0.26
chr19_32179674_32180543	1.77	Sgms1	sphingomyelin synthase 1	16320	0.21
chrX_101428861_101429464	1.77	Nono	non-POU-domain-containing, octamer binding protein	156	0.93
chr4_124714467_124714687	1.76	Sf3a3	splicing factor 3a, subunit 3	199	0.86
chr2_5995574_5995725	1.76	Upf2	UPF2 regulator of nonsense transcripts homolog (yeast)	27690	0.17
chr3_36531782_36532903	1.75	Gm11549	predicted gene 11549	11	0.96
chr5_3646763_3647946	1.75	Gatad1	GATA zinc finger domain containing 1	452	0.65
chr19_32491135_32491491	1.75	Minpp1	multiple inositol polyphosphate histidine phosphatase 1	5390	0.16
chr1_38218052_38218593	1.74	Gm16150	predicted gene 16150	17098	0.18
chr1_136685464_136685771	1.73	Gm19705	predicted gene, 19705	1988	0.24
chr1_194879772_194880217	1.72	Mir3962	microRNA 3962	57993	0.08
chr4_66414553_66415137	1.72	Astn2	astrotactin 2	10234	0.28
chr5_53564312_53564803	1.71	Rbpj	recombination signal binding protein for immunoglobulin kappa J region	8723	0.2
chr6_31125380_31126701	1.71	5330406M23Rik	RIKEN cDNA 5330406M23 gene	15120	0.11
chr15_65744522_65744909	1.70	Efr3a	EFR3 homolog A	42319	0.15
chr10_70096002_70096153	1.70	Ccdc6	coiled-coil domain containing 6	1044	0.64
chr19_46863355_46863576	1.69	Cnnm2	cyclin M2	2195	0.29
chr4_98436713_98437393	1.69	Patj	PATJ, crumbs cell polarity complex component	110	0.97
chr9_120027465_120028032	1.69	Xirp1	xin actin-binding repeat containing 1	4150	0.11
chr2_145794490_145794641	1.69	Rin2	Ras and Rab interactor 2	8403	0.24
chr19_34253411_34255499	1.67	Acta2	actin, alpha 2, smooth muscle, aorta	225	0.92
chr2_6444924_6445246	1.66	Gm13388	predicted gene 13388	9052	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:0016554	cytidine to uridine editing(GO:0016554)
1.0	2.9	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.8	2.4	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.8	4.0	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.8	2.3	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.8	3.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.8	2.3	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.7	2.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.6	2.5	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.6	1.8	GO:0006059	hexitol metabolic process(GO:0006059)
0.6	2.5	GO:0036438	maintenance of lens transparency(GO:0036438)
0.6	2.3	GO:0002584	negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.6	1.7	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.5	2.2	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.5	3.8	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.5	2.1	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.5	2.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.5	3.0	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.5	1.0	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.5	1.4	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.5	1.9	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.5	15.7	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.5	0.9	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
0.5	1.4	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.4	0.9	GO:0002586	regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.4	0.8	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.4	1.2	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.4	1.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.4	1.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.4	4.0	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.3	2.0	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.3	1.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.3	8.9	GO:0035456	response to interferon-beta(GO:0035456)
0.3	1.6	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.3	2.7	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3	1.2	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.3	2.6	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.3	1.2	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.3	0.8	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.3	0.8	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3	1.1	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.3	0.8	GO:0089700	protein kinase D signaling(GO:0089700)
0.3	0.8	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.3	0.8	GO:0006203	dGTP catabolic process(GO:0006203)
0.2	0.7	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.2	1.8	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.2	1.6	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2	1.3	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.2	1.5	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.2	0.4	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.2	0.6	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.2	7.0	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2	0.2	GO:0002445	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.2	1.8	GO:0034501	protein localization to kinetochore(GO:0034501)
0.2	1.4	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.2	8.5	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.2	0.4	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.2	0.8	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2	0.8	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.2	0.6	GO:0002086	diaphragm contraction(GO:0002086)
0.2	1.3	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.2	0.4	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.2	0.5	GO:0001692	histamine metabolic process(GO:0001692)
0.2	0.7	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.2	0.3	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.2	0.9	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.2	0.3	GO:0010159	specification of organ position(GO:0010159)
0.2	0.7	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.2	1.8	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.2	1.2	GO:0007220	Notch receptor processing(GO:0007220)
0.2	1.3	GO:0046069	cGMP catabolic process(GO:0046069)
0.2	1.0	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.2	0.9	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.2	0.6	GO:0008228	opsonization(GO:0008228)
0.2	0.9	GO:0071763	nuclear membrane organization(GO:0071763)
0.2	0.8	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.2	0.3	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.2	0.6	GO:0060066	oviduct development(GO:0060066)
0.2	0.3	GO:1902075	cellular response to salt(GO:1902075)
0.2	0.5	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1	0.6	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.1	2.6	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.1	0.7	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.5	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.1	0.7	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	0.7	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	0.4	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.1	0.5	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.1	0.5	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.1	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.3	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.1	0.4	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1	0.5	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	3.9	GO:0048525	negative regulation of viral process(GO:0048525)
0.1	0.4	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.4	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.1	2.7	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.5	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	0.8	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.6	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.7	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1	0.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.2	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.1	1.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.6	GO:1902222	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.4	GO:0030091	protein repair(GO:0030091)
0.1	0.3	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.1	0.4	GO:0042701	progesterone secretion(GO:0042701)
0.1	0.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.3	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.2	GO:2000834	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.1	0.4	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.2	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.1	0.7	GO:0071318	cellular response to ATP(GO:0071318)
0.1	2.0	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.1	0.3	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.1	0.2	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.1	0.9	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.3	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.1	0.3	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1	0.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	1.7	GO:0014829	vascular smooth muscle contraction(GO:0014829)
0.1	0.6	GO:0035459	cargo loading into vesicle(GO:0035459)
0.1	1.2	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.1	0.7	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.3	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.6	GO:0097264	self proteolysis(GO:0097264)
0.1	0.2	GO:0002432	granuloma formation(GO:0002432)
0.1	0.6	GO:0070269	pyroptosis(GO:0070269)
0.1	0.9	GO:0000042	protein targeting to Golgi(GO:0000042)
0.1	0.2	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	0.5	GO:0001302	replicative cell aging(GO:0001302)
0.1	0.4	GO:0018101	protein citrullination(GO:0018101)
0.1	0.3	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.1	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.1	0.9	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	0.5	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.1	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
0.1	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1	0.6	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	0.4	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.1	0.6	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.1	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	0.3	GO:0036295	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1	0.4	GO:0044539	long-chain fatty acid import(GO:0044539)
0.1	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	1.7	GO:0047496	vesicle transport along microtubule(GO:0047496)
0.1	0.1	GO:0014820	tonic smooth muscle contraction(GO:0014820)
0.1	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	0.3	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.1	0.3	GO:0003164	His-Purkinje system development(GO:0003164)
0.1	0.2	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1	0.7	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.1	0.1	GO:0007494	midgut development(GO:0007494)
0.1	1.0	GO:0002093	auditory receptor cell morphogenesis(GO:0002093)
0.1	0.1	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1	0.1	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.1	0.4	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.1	0.2	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.2	GO:0070889	platelet alpha granule organization(GO:0070889)
0.1	0.2	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.1	0.5	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.4	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.1	0.1	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1	0.4	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.3	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.3	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	2.4	GO:0019882	antigen processing and presentation(GO:0019882)
0.1	0.2	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.1	0.3	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.1	0.2	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.1	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.1	0.2	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1	0.2	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.2	GO:0033216	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.1	0.5	GO:0019985	translesion synthesis(GO:0019985)
0.1	0.3	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1	0.3	GO:0007035	vacuolar acidification(GO:0007035)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.1	1.6	GO:0006754	ATP biosynthetic process(GO:0006754)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1	0.6	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.1	0.3	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.2	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.2	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.2	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.7	GO:1901739	regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.0	0.1	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.2	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0044090	positive regulation of vacuole organization(GO:0044090)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.0	GO:1901859	regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.1	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.7	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.4	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.6	GO:0009992	cellular water homeostasis(GO:0009992)
0.0	0.1	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:1903011	negative regulation of bone development(GO:1903011)
0.0	0.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.1	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0060312	regulation of blood vessel remodeling(GO:0060312)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.1	GO:0048757	endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0	0.1	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0060872	semicircular canal development(GO:0060872)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.6	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.4	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.0	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694)
0.0	0.4	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.4	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	1.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.0	0.0	GO:0086043	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.2	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.2	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.1	GO:1901874	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.2	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.1	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.1	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.6	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.0	GO:0044854	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0	0.3	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.2	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.1	GO:0050904	diapedesis(GO:0050904)
0.0	0.2	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.0	GO:0043320	natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:1903333	negative regulation of protein folding(GO:1903333)
0.0	0.7	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	1.0	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.3	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.0	0.1	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.0	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0009197	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0	0.4	GO:0008272	sulfate transport(GO:0008272)
0.0	0.3	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0097286	iron ion import(GO:0097286)
0.0	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.1	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.1	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.0	0.2	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.4	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.2	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	4.1	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.3	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.0	0.1	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.1	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.1	GO:0006533	fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0030035	microspike assembly(GO:0030035)
0.0	0.1	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.0	0.2	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.2	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:2000739	regulation of mesenchymal stem cell differentiation(GO:2000739)
0.0	0.1	GO:0009074	aromatic amino acid family catabolic process(GO:0009074)
0.0	0.5	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.1	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.6	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.8	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.2	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.0	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.3	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.5	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	0.0	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0071503	response to heparin(GO:0071503) cellular response to heparin(GO:0071504) positive regulation of metanephric glomerulus development(GO:0072300)
0.0	0.1	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.0	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0	0.0	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.0	0.1	GO:2000316	regulation of T-helper 17 type immune response(GO:2000316)
0.0	0.0	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.0	0.1	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.2	GO:2000671	motor neuron apoptotic process(GO:0097049) regulation of motor neuron apoptotic process(GO:2000671)
0.0	0.7	GO:1901184	regulation of ERBB signaling pathway(GO:1901184)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	2.6	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	0.1	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.7	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115)
0.0	0.8	GO:0007569	cell aging(GO:0007569)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.2	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.2	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0030220	platelet formation(GO:0030220)
0.0	0.0	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.4	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.1	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.0	0.0	GO:0015744	succinate transport(GO:0015744)
0.0	0.1	GO:0014857	regulation of skeletal muscle cell proliferation(GO:0014857)
0.0	0.0	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.0	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0	0.0	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.4	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:2000002	negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
0.0	0.1	GO:0071042	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.1	GO:2000811	negative regulation of anoikis(GO:2000811)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.2	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.3	GO:0060688	regulation of morphogenesis of a branching structure(GO:0060688)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.5	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.1	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0031643	positive regulation of myelination(GO:0031643)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.0	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.1	GO:0032570	response to progesterone(GO:0032570)
0.0	0.0	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.0	0.0	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.0	0.1	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:1902306	negative regulation of sodium ion transmembrane transport(GO:1902306)
0.0	0.2	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.0	GO:0070100	regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.3	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0	0.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.0	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:1902608	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.0	0.0	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.8	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.0	0.1	GO:0046060	dATP metabolic process(GO:0046060)
0.0	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.0	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0015867	ATP transport(GO:0015867)
0.0	0.3	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.0	0.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.1	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.1	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0	0.0	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.0	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.0	GO:1901858	regulation of mitochondrial DNA metabolic process(GO:1901858)
0.0	0.2	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.1	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0	0.3	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.1	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.0	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.0	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.1	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.0	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.2	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.0	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.0	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.0	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.4	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.1	GO:0048242	epinephrine secretion(GO:0048242)
0.0	0.0	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.0	GO:0002838	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0	0.0	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.0	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0044546	NLRP3 inflammasome complex assembly(GO:0044546)
0.0	0.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.1	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.0	GO:0015886	heme transport(GO:0015886)
0.0	0.2	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.1	GO:0010666	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101)
0.0	0.1	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.0	0.0	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.0	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0001765	membrane raft assembly(GO:0001765)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.0	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.0	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.2	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.0	GO:0035590	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.3	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0	0.0	GO:0061010	primary lung bud formation(GO:0060431) gall bladder development(GO:0061010)
0.0	0.2	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0021590	cerebellum maturation(GO:0021590)
0.0	0.0	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.0	0.9	GO:0006302	double-strand break repair(GO:0006302)
0.0	0.2	GO:0033014	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	5.3	GO:0045293	mRNA editing complex(GO:0045293)
1.1	6.7	GO:1990462	omegasome(GO:1990462)
1.0	4.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.6	5.6	GO:0020003	symbiont-containing vacuole(GO:0020003)
0.6	1.8	GO:0097454	Schwann cell microvillus(GO:0097454)
0.5	2.7	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.5	2.5	GO:1990111	spermatoproteasome complex(GO:1990111)
0.4	1.5	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.4	1.8	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.3	1.6	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.3	0.9	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.3	1.2	GO:1990246	uniplex complex(GO:1990246)
0.3	2.8	GO:0042405	nuclear inclusion body(GO:0042405)
0.2	0.9	GO:0002079	inner acrosomal membrane(GO:0002079)
0.2	1.5	GO:0042382	paraspeckles(GO:0042382)
0.2	0.8	GO:0042825	TAP complex(GO:0042825)
0.2	0.6	GO:0070552	BRISC complex(GO:0070552)
0.2	2.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.2	2.1	GO:0042612	MHC class I protein complex(GO:0042612)
0.2	0.9	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	0.7	GO:0030478	actin cap(GO:0030478)
0.2	5.6	GO:0015030	Cajal body(GO:0015030)
0.2	2.4	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.2	0.6	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.6	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.4	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.8	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	1.0	GO:0035253	ciliary rootlet(GO:0035253)
0.1	0.3	GO:0043511	inhibin complex(GO:0043511)
0.1	7.6	GO:0030863	cortical cytoskeleton(GO:0030863)
0.1	0.3	GO:0005745	m-AAA complex(GO:0005745)
0.1	1.2	GO:0000421	autophagosome membrane(GO:0000421)
0.1	1.2	GO:0031430	M band(GO:0031430)
0.1	1.5	GO:0097225	sperm midpiece(GO:0097225)
0.1	1.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	0.2	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.1	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.9	GO:0097386	glial cell projection(GO:0097386)
0.1	0.1	GO:0031523	Myb complex(GO:0031523)
0.1	0.1	GO:0071203	WASH complex(GO:0071203)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.1	2.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	0.2	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.1	0.3	GO:0097422	tubular endosome(GO:0097422)
0.1	0.3	GO:0042629	mast cell granule(GO:0042629)
0.1	0.7	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	2.0	GO:0005720	nuclear heterochromatin(GO:0005720)
0.1	1.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	0.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.3	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.1	0.2	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.1	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	2.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.5	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.1	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	1.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.6	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	1.4	GO:0005776	autophagosome(GO:0005776)
0.0	0.3	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.2	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.8	GO:0030057	desmosome(GO:0030057)
0.0	0.3	GO:0001527	microfibril(GO:0001527)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.9	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.1	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.4	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.1	GO:0044393	microspike(GO:0044393)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.1	GO:0000802	transverse filament(GO:0000802)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	2.8	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	1.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	2.7	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.6	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	1.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.7	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.0	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.3	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	1.7	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	1.4	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.2	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.4	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	3.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.3	GO:0032155	cell division site(GO:0032153) cell division site part(GO:0032155)
0.0	0.0	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.5	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	1.1	GO:0005770	late endosome(GO:0005770)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.0	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	12.5	GO:0005615	extracellular space(GO:0005615)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.0	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.0	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.4	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.5	16.2	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.7	2.7	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.5	1.5	GO:0045503	dynein light chain binding(GO:0045503)
0.5	7.0	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.5	4.3	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.5	2.3	GO:0042609	CD4 receptor binding(GO:0042609)
0.4	2.6	GO:0050897	cobalt ion binding(GO:0050897)
0.4	1.8	GO:0031849	olfactory receptor binding(GO:0031849)
0.4	1.4	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.3	2.8	GO:0034046	poly(G) binding(GO:0034046)
0.3	0.7	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.3	1.7	GO:0017040	ceramidase activity(GO:0017040)
0.3	1.6	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.3	2.9	GO:0031386	protein tag(GO:0031386)
0.3	0.9	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.3	0.9	GO:0042296	ISG15 transferase activity(GO:0042296)
0.3	5.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	9.0	GO:0042605	peptide antigen binding(GO:0042605)
0.3	0.8	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.2	0.7	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2	7.0	GO:0005132	type I interferon receptor binding(GO:0005132)
0.2	0.6	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	0.6	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.2	4.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.2	0.6	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.2	0.8	GO:0034548	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.2	1.0	GO:0070883	pre-miRNA binding(GO:0070883)
0.2	1.4	GO:0050700	CARD domain binding(GO:0050700)
0.2	0.6	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	0.7	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.2	2.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	1.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.2	0.6	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.2	0.5	GO:0031711	bradykinin receptor binding(GO:0031711)
0.2	0.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	1.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.2	0.5	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	0.7	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	1.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.7	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	3.6	GO:0052715	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1	1.3	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1	0.4	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.8	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.1	8.0	GO:0003727	single-stranded RNA binding(GO:0003727)
0.1	0.2	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.1	2.6	GO:0030332	cyclin binding(GO:0030332)
0.1	1.3	GO:0001671	ATPase activator activity(GO:0001671)
0.1	2.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	2.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.2	GO:0043199	sulfate binding(GO:0043199)
0.1	0.3	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.5	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	16.7	GO:0003924	GTPase activity(GO:0003924)
0.1	0.8	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.9	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.4	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.1	0.6	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.1	0.5	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.5	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.1	0.3	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.3	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.6	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.5	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.3	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.1	1.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.4	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.9	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	0.8	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.7	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.1	0.4	GO:0043814	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.1	0.3	GO:0030984	kininogen binding(GO:0030984)
0.1	0.3	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.1	0.6	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	1.1	GO:0001848	complement binding(GO:0001848)
0.1	0.1	GO:0019187	beta-1,4-mannosyltransferase activity(GO:0019187)
0.1	0.4	GO:0035198	miRNA binding(GO:0035198)
0.1	0.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.9	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1	0.2	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.1	0.4	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.7	GO:0001223	transcription coactivator binding(GO:0001223)
0.1	0.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	0.3	GO:0008494	translation activator activity(GO:0008494)
0.1	0.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.1	GO:0035276	alcohol dehydrogenase activity, zinc-dependent(GO:0004024) ethanol binding(GO:0035276)
0.1	0.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.1	0.6	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	2.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.4	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.7	GO:0005521	lamin binding(GO:0005521)
0.0	2.1	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors(GO:0016903)
0.0	0.9	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	2.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.6	GO:0043274	phospholipase binding(GO:0043274)
0.0	2.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.4	GO:0070513	death domain binding(GO:0070513)
0.0	8.9	GO:0070735	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.2	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.5	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.4	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.2	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.4	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.4	GO:0008758	thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0	0.9	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.2	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	1.0	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	1.8	GO:0046921	alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.5	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.4	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.0	0.7	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	2.2	GO:0005496	steroid binding(GO:0005496)
0.0	0.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.9	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.0	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	2.6	GO:0005525	GTP binding(GO:0005525)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.7	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.0	GO:0001031	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.2	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.7	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.0	0.0	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.1	GO:0015265	urea channel activity(GO:0015265)
0.0	0.8	GO:0016209	antioxidant activity(GO:0016209)
0.0	0.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	1.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0034618	arginine binding(GO:0034618)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.8	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.5	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.0	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.1	GO:0034882	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0	0.0	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.0	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.4	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.0	GO:0070815	procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.5	GO:0005518	collagen binding(GO:0005518)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.0	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.0	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	3.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	1.5	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	2.4	PID MYC PATHWAY	C-MYC pathway
0.1	2.7	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	3.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	3.0	PID PLK1 PATHWAY	PLK1 signaling events
0.1	0.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	0.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	1.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	ST STAT3 PATHWAY	STAT3 Pathway
0.0	1.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	1.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	1.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.8	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.9	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.8	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.4	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.7	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.9	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	1.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	1.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.9	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.6	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	4.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.4	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.3	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	PID ATM PATHWAY	ATM pathway
0.0	0.0	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	2.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	27.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.3	3.7	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.3	6.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.3	2.6	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	4.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2	1.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.2	1.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	1.7	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	1.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	1.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	1.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.9	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	0.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	0.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	1.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	7.4	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	3.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	2.3	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	0.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.7	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	2.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	1.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.6	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	1.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	2.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.8	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.0	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.5	REACTOME TRANSLATION	Genes involved in Translation
0.0	1.2	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements

Results for Irf3

Z-value: 1.69

Motif logo

Transcription factors associated with Irf3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Irf3 motif across conditions

Conditions sorted by the z-value of the Irf3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: