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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Irx4

Z-value: 0.94

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Transcription factors associated with Irx4

Gene Symbol	Gene ID	Gene Info
Irx4 Ensembl NCBI MGI UniProt	ENSMUSG00000021604.9	Iroquois homeobox 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr13_73264474_73265993	Irx4	4736	0.175386	0.50	5.4e-05	Click!
chr13_73262153_73264451	Irx4	2805	0.220576	0.30	1.9e-02	Click!
chr13_73266702_73266853	Irx4	6280	0.162190	0.24	7.0e-02	Click!
chr13_73260273_73261531	Irx4	405	0.820890	0.18	1.6e-01	Click!
chr13_73266364_73266515	Irx4	5942	0.164474	-0.06	6.4e-01	Click!

Activity of the Irx4 motif across conditions

Conditions sorted by the z-value of the Irx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_40724876_40726660	3.07	Dnaja1	DnaJ heat shock protein family (Hsp40) member A1	1719	0.23
chr2_9880695_9881908	2.29	4930412O13Rik	RIKEN cDNA 4930412O13 gene	49	0.95
chr1_78186833_78187893	2.23	Pax3	paired box 3	9475	0.23
chr10_68278824_68280301	1.92	Arid5b	AT rich interactive domain 5B (MRF1-like)	822	0.67
chr10_102513522_102514467	1.72	Rassf9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	1738	0.36
chr14_98164357_98165375	1.67	Dach1	dachshund family transcription factor 1	4677	0.28
chr8_109360134_109360931	1.65	Gm1943	predicted gene 1943	19668	0.22
chr9_69763544_69764965	1.49	B230323A14Rik	RIKEN cDNA B230323A14 gene	3108	0.23
chr11_105758864_105759427	1.44	Gm11652	predicted gene 11652	14373	0.21
chr14_99296244_99296506	1.38	Klf5	Kruppel-like factor 5	2316	0.26
chr16_17122394_17122914	1.36	2610318N02Rik	RIKEN cDNA 2610318N02 gene	894	0.27
chr4_40772571_40773117	1.32	Psenen-ps	presenilin enhancer gamma secretase subunit, pseudogene	2720	0.18
chr9_41611530_41612990	1.29	Gm48737	predicted gene, 48737	6732	0.12
chr3_30008541_30009027	1.28	Mecom	MDS1 and EVI1 complex locus	2655	0.27
chr7_89405888_89406433	1.26	Fzd4	frizzled class receptor 4	1805	0.24
chr11_102607669_102607862	1.22	Fzd2	frizzled class receptor 2	3369	0.13
chr13_23505562_23506916	1.21	n-TStga1	nuclear encoded tRNA serine 1 (anticodon TGA)	11903	0.05
chr5_100689374_100689525	1.20	Coq2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	14309	0.13
chr11_60810014_60810742	1.19	Shmt1	serine hydroxymethyltransferase 1 (soluble)	713	0.45
chr1_119996644_119997759	1.18	Cfap221	cilia and flagella associated protein 221	11	0.97
chr9_78476606_78478437	1.17	Gm26377	predicted gene, 26377	1114	0.3
chr5_53592640_53593680	1.16	Rbpj	recombination signal binding protein for immunoglobulin kappa J region	2179	0.36
chr18_82888592_82889295	1.16	Gm30889	predicted gene, 30889	13135	0.14
chr18_62927171_62927454	1.16	Apcdd1	adenomatosis polyposis coli down-regulated 1	4806	0.22
chr13_23575053_23575204	1.14	Gm44359	predicted gene, 44359	275	0.5
chr19_24675275_24675426	1.14	Tmem252	transmembrane protein 252	1342	0.46
chr12_36313868_36315206	1.11	Sostdc1	sclerostin domain containing 1	398	0.82
chr12_100177619_100177946	1.11	Gm48296	predicted gene, 48296	9229	0.13
chr19_53460190_53461095	1.11	4833407H14Rik	RIKEN cDNA 4833407H14 gene	20	0.97
chr17_85485071_85487191	1.10	Rpl31-ps16	ribosomal protein L31, pseudogene 16	12502	0.23
chr10_125785515_125788000	1.08	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	179411	0.03
chr2_60672831_60673749	1.08	Itgb6	integrin beta 6	403	0.88
chr11_95990052_95990605	1.07	Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	7717	0.1
chr2_31770592_31771657	1.06	Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	10951	0.15
chr13_3890794_3891171	1.06	Net1	neuroepithelial cell transforming gene 1	2451	0.19
chr15_63626797_63626948	1.04	Gm5473	predicted pseudogene 5473	4825	0.25
chr1_162222542_162222984	1.03	Mir214	microRNA 214	605	0.68
chr11_99366480_99366631	1.02	Krt28	keratin 28	8348	0.09
chr7_66115594_66116946	1.02	Gm23042	predicted gene, 23042	3133	0.16
chr18_3509793_3510792	1.01	Bambi	BMP and activin membrane-bound inhibitor	2369	0.24
chr7_127909951_127910102	1.00	Kat8	K(lysine) acetyltransferase 8	2490	0.1
chr8_45658542_45659771	0.99	Sorbs2	sorbin and SH3 domain containing 2	352	0.89
chr11_113120692_113120843	0.99	2610035D17Rik	RIKEN cDNA 2610035D17 gene	52310	0.16
chr14_95354605_95355258	0.98	Gm48994	predicted gene, 48994	15301	0.19
chr1_19240831_19241749	0.97	Gm28340	predicted gene 28340	1435	0.44
chr7_70365047_70366578	0.97	B130024G19Rik	RIKEN cDNA B130024G19 gene	653	0.47
chr1_68046479_68047396	0.96	Gm15671	predicted gene 15671	22694	0.22
chr4_107732796_107732947	0.95	1700047F07Rik	RIKEN cDNA 1700047F07 gene	25814	0.09
chr1_136231257_136232167	0.95	Inava	innate immunity activator	1402	0.26
chr11_77702697_77702848	0.95	Nufip2	nuclear fragile X mental retardation protein interacting protein 2	15171	0.12
chr7_143051480_143051631	0.94	Cd81	CD81 antigen	1184	0.3
chr9_107697806_107698451	0.94	Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	5414	0.1
chr12_54759420_54759571	0.94	Snx6	sorting nexin 6	988	0.33
chr7_62417849_62418010	0.94	Mkrn3	makorin, ring finger protein, 3	2210	0.26
chr10_97566192_97567945	0.93	Lum	lumican	1940	0.32
chrX_51035742_51036099	0.93	Gm5387	predicted gene 5387	8043	0.22
chr13_48540456_48540998	0.91	Mirlet7a-1	microRNA let7a-1	2455	0.12
chr6_52231944_52233433	0.91	Hoxa10	homeobox A10	636	0.35
chr3_24782863_24783977	0.90	Naaladl2	N-acetylated alpha-linked acidic dipeptidase-like 2	202	0.97
chr2_20547166_20548761	0.90	Etl4	enhancer trap locus 4	17	0.99
chr8_68082976_68083127	0.90	Psd3	pleckstrin and Sec7 domain containing 3	20765	0.24
chrX_100729323_100729474	0.89	Gdpd2	glycerophosphodiester phosphodiesterase domain containing 2	475	0.74
chr3_8866866_8867164	0.89	Gm15467	predicted gene 15467	14184	0.18
chr18_37178155_37179152	0.88	Gm10544	predicted gene 10544	131	0.94
chr17_22866063_22866815	0.88	Zfp945	zinc finger protein 945	666	0.63
chr2_34878591_34878742	0.88	Psmd5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	3698	0.13
chr8_108819814_108820929	0.87	Gm38318	predicted gene, 38318	47191	0.15
chr13_91878420_91878571	0.87	Ckmt2	creatine kinase, mitochondrial 2	1610	0.39
chr2_115213236_115213465	0.86	Gm28494	predicted gene 28494	7358	0.28
chr17_34111979_34112156	0.86	Brd2	bromodomain containing 2	1665	0.12
chr9_63959278_63959939	0.86	Gm36033	predicted gene, 36033	22487	0.16
chr13_72400649_72401264	0.86	Gm47836	predicted gene, 47836	29309	0.16
chr9_72812558_72813462	0.85	Prtg	protogenin	6136	0.13
chr8_12382712_12383684	0.85	Sox1ot	Sox1 overlapping transcript	2573	0.2
chr13_111484767_111485766	0.85	Gpbp1	GC-rich promoter binding protein 1	2446	0.28
chr12_54316589_54317566	0.85	Gm47552	predicted gene, 47552	62	0.97
chr7_142662290_142664788	0.85	Igf2os	insulin-like growth factor 2, opposite strand	1599	0.21
chrX_96457400_96457738	0.84	Heph	hephaestin	1141	0.37
chr9_64017614_64019400	0.84	Smad6	SMAD family member 6	1520	0.33
chr8_8640607_8640758	0.84	Efnb2	ephrin B2	1319	0.23
chr9_45042261_45043690	0.83	Mpzl2	myelin protein zero-like 2	279	0.8
chr13_21930797_21931759	0.83	Gm44456	predicted gene, 44456	6262	0.07
chr17_70747438_70748697	0.83	5031415H12Rik	RIKEN cDNA 5031415H12 gene	7515	0.19
chr4_83048206_83048487	0.82	Frem1	Fras1 related extracellular matrix protein 1	3821	0.26
chr6_120496083_120496234	0.82	Tmem121b	transmembrane protein 121B	2351	0.2
chr8_44997847_44999430	0.82	Gm2366	predicted gene 2366	23747	0.17
chr13_28295328_28295479	0.81	Gm47172	predicted gene, 47172	9834	0.23
chr3_31098961_31099226	0.81	Skil	SKI-like	2260	0.31
chr12_119236519_119236678	0.81	Itgb8	integrin beta 8	2172	0.36
chr3_31099281_31100546	0.80	Skil	SKI-like	3080	0.26
chr14_16554767_16555445	0.78	Rarb	retinoic acid receptor, beta	19939	0.21
chr1_152084503_152085500	0.78	1700025G04Rik	RIKEN cDNA 1700025G04 gene	4969	0.28
chr6_113081923_113082765	0.78	Setd5	SET domain containing 5	4705	0.13
chr9_29943252_29944148	0.78	Ntm	neurotrimin	19419	0.28
chr11_88118661_88119834	0.77	Cuedc1	CUE domain containing 1	19957	0.14
chr6_22002725_22003422	0.76	Cped1	cadherin-like and PC-esterase domain containing 1	13993	0.24
chr8_84068425_84069043	0.76	C330011M18Rik	RIKEN cDNA C330011M18 gene	1447	0.17
chr1_182016916_182017691	0.75	Enah	ENAH actin regulator	2358	0.22
chr14_22168418_22168574	0.75	Gm7480	predicted gene 7480	132393	0.04
chr11_87462490_87462776	0.75	Rnu3b4	U3B small nuclear RNA 4	347	0.75
chr3_154329308_154331090	0.74	Lhx8	LIM homeobox protein 8	140	0.88
chr3_54358382_54359181	0.74	Postn	periostin, osteoblast specific factor	2328	0.42
chr9_71895839_71896117	0.73	Tcf12	transcription factor 12	7	0.96
chr6_47925497_47925648	0.73	Zfp212	Zinc finger protein 212	734	0.56
chr6_4738402_4738555	0.73	Sgce	sarcoglycan, epsilon	1729	0.31
chr6_48705812_48706743	0.72	Gimap6	GTPase, IMAP family member 6	41	0.93
chr6_92480350_92481798	0.72	Prickle2	prickle planar cell polarity protein 2	318	0.93
chr7_25185974_25186125	0.71	Pou2f2	POU domain, class 2, transcription factor 2	6323	0.1
chr6_52224029_52224693	0.71	Hoxa9	homeobox A9	1828	0.1
chrX_164374431_164375504	0.71	Vegfd	vascular endothelial growth factor D	1589	0.39
chr9_71891771_71892231	0.71	Tcf12	transcription factor 12	3984	0.14
chr1_156838616_156839715	0.70	Angptl1	angiopoietin-like 1	223	0.86
chr1_191300499_191300650	0.70	Nenf	neuron derived neurotrophic factor	17620	0.13
chr6_30733644_30733830	0.70	Mest	mesoderm specific transcript	231	0.88
chr13_24760759_24760932	0.70	Gmnn	geminin	595	0.68
chr3_55786777_55788366	0.70	Nbea	neurobeachin	374	0.87
chr10_28114251_28114402	0.69	Ptprk	protein tyrosine phosphatase, receptor type, K	39316	0.17
chr15_11897737_11898020	0.69	Npr3	natriuretic peptide receptor 3	6890	0.2
chr15_77301305_77301614	0.69	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	5146	0.17
chr3_19622651_19622802	0.68	1700064H15Rik	RIKEN cDNA 1700064H15 gene	5951	0.17
chr15_83734436_83734715	0.68	Scube1	signal peptide, CUB domain, EGF-like 1	9554	0.22
chr13_55962186_55963636	0.67	Gm47071	predicted gene, 47071	39354	0.14
chr10_81340294_81340452	0.67	Gipc3	GIPC PDZ domain containing family, member 3	2893	0.08
chr11_106781197_106781348	0.67	Mir3064	microRNA 3064	1487	0.18
chr8_124099096_124099358	0.67	Gm45732	predicted gene 45732	50815	0.09
chr10_99556033_99556477	0.67	Gm48085	predicted gene, 48085	18186	0.17
chr13_90012041_90013007	0.67	Xrcc4	X-ray repair complementing defective repair in Chinese hamster cells 4	76558	0.09
chr14_122465313_122465487	0.67	Zic5	zinc finger protein of the cerebellum 5	277	0.85
chr13_54623790_54623941	0.67	Faf2	Fas associated factor family member 2	2027	0.2
chr17_36783693_36783844	0.65	H2-M10.5	histocompatibility 2, M region locus 10.5	10858	0.08
chr9_21900907_21901058	0.65	Rab3d	RAB3D, member RAS oncogene family	17107	0.08
chr1_118630581_118630732	0.64	Tfcp2l1	transcription factor CP2-like 1	2710	0.21
chr18_60528205_60528373	0.64	Dctn4	dynactin 4	2071	0.27
chr4_44710605_44711261	0.64	Pax5	paired box 5	446	0.78
chr12_101080889_101081491	0.64	D130020L05Rik	RIKEN cDNA D130020L05 gene	1261	0.3
chr11_102631042_102631688	0.63	2810433D01Rik	RIKEN cDNA 2810433D01 gene	6949	0.1
chr14_55658543_55658694	0.63	Gm49299	predicted gene, 49299	410	0.53
chr5_75148315_75152589	0.63	Pdgfra	platelet derived growth factor receptor, alpha polypeptide	1840	0.2
chr9_33233802_33233953	0.63	Gm47775	predicted gene, 47775	62367	0.12
chr11_89175150_89175777	0.62	Gm11497	predicted gene 11497	48757	0.12
chr10_81237497_81237648	0.62	Zfr2	zinc finger RNA binding protein 2	4385	0.07
chr17_28107084_28107235	0.62	Tcp11	t-complex protein 11	26520	0.09
chr4_48680671_48681073	0.62	Gm12439	predicted gene 12439	5716	0.2
chr18_55133490_55134601	0.62	Gm34073	predicted gene, 34073	9529	0.19
chrX_53052299_53053294	0.61	Gm28730	predicted gene 28730	181	0.73
chr17_73948968_73950593	0.61	Xdh	xanthine dehydrogenase	312	0.89
chr16_94179302_94180102	0.61	Hlcs	holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)	4702	0.13
chr1_106629982_106630261	0.60	Gm37053	predicted gene, 37053	23251	0.19
chr2_31691580_31691731	0.60	Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	2044	0.18
chr14_28165088_28165346	0.60	Erc2	ELKS/RAB6-interacting/CAST family member 2	118789	0.06
chr17_71186478_71186817	0.60	Lpin2	lipin 2	2669	0.23
chr9_83686101_83687074	0.60	Gm36120	predicted gene, 36120	938	0.58
chr2_146834060_146838027	0.60	Gm14114	predicted gene 14114	3689	0.27
chr2_49719816_49720541	0.60	Kif5c	kinesin family member 5C	2389	0.34
chr11_62077966_62078226	0.60	Specc1	sperm antigen with calponin homology and coiled-coil domains 1	999	0.57
chr10_121295275_121295426	0.59	Tbc1d30	TBC1 domain family, member 30	702	0.64
chr11_84520959_84524590	0.59	Lhx1	LIM homeobox protein 1	63	0.97
chr15_79779036_79779187	0.59	Dnal4	dynein, axonemal, light chain 4	1262	0.28
chr8_26747332_26748017	0.59	Gm45646	predicted gene 45646	12887	0.18
chr5_37895892_37896442	0.59	Gm20052	predicted gene, 20052	1460	0.47
chr9_64918332_64919221	0.59	Dennd4a	DENN/MADD domain containing 4A	6293	0.16
chr10_38553439_38554580	0.58	Gm22911	predicted gene, 22911	61472	0.14
chr12_117844767_117845215	0.58	Cdca7l	cell division cycle associated 7 like	1103	0.55
chr10_103114994_103115145	0.58	Gm25376	predicted gene, 25376	6167	0.23
chr2_45103994_45106973	0.58	Zeb2	zinc finger E-box binding homeobox 2	4593	0.23
chr11_75458165_75458341	0.58	Mir22hg	Mir22 host gene (non-protein coding)	3286	0.1
chr11_6441857_6442008	0.57	H2az2	H2A.Z histone variant 2	2420	0.13
chr8_71402576_71402783	0.57	Babam1	BRISC and BRCA1 A complex member 1	105	0.92
chr9_35424475_35426234	0.57	Cdon	cell adhesion molecule-related/down-regulated by oncogenes	1766	0.31
chr1_58112719_58113882	0.57	Aox3	aldehyde oxidase 3	114	0.97
chr4_150120468_150120782	0.57	Slc2a5	solute carrier family 2 (facilitated glucose transporter), member 5	1342	0.24
chr10_19443494_19443750	0.56	Gm33104	predicted gene, 33104	43093	0.15
chr16_89958962_89959698	0.56	Tiam1	T cell lymphoma invasion and metastasis 1	1407	0.55
chr19_39333834_39333985	0.56	Cyp2c72-ps	cytochrome P450, family 2, subfamily c, polypeptide 72, pseudogene	13458	0.22
chr13_21789171_21790009	0.56	Hist1h2bp	histone cluster 1, H2bp	2082	0.08
chr10_80787587_80787738	0.56	Dot1l	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	1401	0.2
chr5_115153313_115153764	0.56	Mlec	malectin	2492	0.15
chr5_125215421_125215673	0.56	Ncor2	nuclear receptor co-repressor 2	36328	0.14
chr19_45695467_45696472	0.55	Fbxw4	F-box and WD-40 domain protein 4	35657	0.12
chr9_42881375_42881659	0.55	Gm27509	predicted gene, 27509	19388	0.2
chr13_116705228_116706295	0.55	Gm47914	predicted gene, 47914	28056	0.17
chr17_50643550_50643771	0.54	Plcl2	phospholipase C-like 2	36666	0.2
chr9_91407021_91407470	0.54	Gm29478	predicted gene 29478	2771	0.2
chr13_55923232_55923960	0.54	Gm47071	predicted gene, 47071	78669	0.07
chr6_127079642_127080865	0.54	Fgf23	fibroblast growth factor 23	7351	0.12
chr15_101039576_101041027	0.53	Tmdd1	transmembrane and death domain 1	7096	0.15
chr9_61944794_61945642	0.53	Kif23	kinesin family member 23	1518	0.41
chr14_120390247_120390398	0.53	Gm26679	predicted gene, 26679	1337	0.49
chr11_51389668_51390213	0.53	Col23a1	collagen, type XXIII, alpha 1	100020	0.06
chr5_113463755_113463993	0.53	Wscd2	WSC domain containing 2	26459	0.18
chr4_108218802_108219449	0.53	Zyg11a	zyg-11 family member A, cell cycle regulator	1077	0.46
chr17_15702797_15702948	0.53	Chd1	chromodomain helicase DNA binding protein 1	2095	0.33
chr17_80576758_80577835	0.53	Cdkl4	cyclin-dependent kinase-like 4	188	0.94
chr11_5151571_5152721	0.53	Emid1	EMI domain containing 1	91	0.97
chr5_150195744_150197001	0.52	Fry	FRY microtubule binding protein	94	0.97
chr3_95933143_95933294	0.52	Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	417	0.69
chr8_88140381_88140532	0.52	Gm9988	predicted gene 9988	1939	0.19
chr1_161183632_161183900	0.52	Gm6185	predicted gene 6185	6830	0.14
chr16_95456632_95459094	0.52	Erg	ETS transcription factor	1382	0.55
chr5_48089221_48089372	0.52	Gm43426	predicted gene 43426	31245	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx4

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.6	GO:0060594	mammary gland specification(GO:0060594)
0.3	1.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.2	1.1	GO:0009115	xanthine catabolic process(GO:0009115)
0.2	1.5	GO:0060613	fat pad development(GO:0060613)
0.2	1.2	GO:0090527	actin filament reorganization(GO:0090527)
0.2	0.6	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.2	0.5	GO:0009177	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.2	0.7	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2	0.5	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2	0.5	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.2	0.5	GO:0060847	endothelial cell fate specification(GO:0060847)
0.2	0.8	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	0.6	GO:1904528	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.1	0.5	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	1.0	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	0.4	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.2	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.1	0.3	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.1	0.3	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.3	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1	0.4	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.1	0.2	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.1	0.3	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.1	0.6	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	0.6	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.3	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.3	GO:0051697	protein delipidation(GO:0051697)
0.1	0.2	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1	0.2	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1	0.2	GO:0030035	microspike assembly(GO:0030035)
0.1	0.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.4	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.1	0.2	GO:0033058	directional locomotion(GO:0033058)
0.1	0.1	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1	0.2	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1	0.4	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.1	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1	0.5	GO:0003264	cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264) regulation of secondary heart field cardioblast proliferation(GO:0003266)
0.1	0.1	GO:0038091	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1	0.3	GO:0003383	apical constriction(GO:0003383)
0.1	0.1	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.1	0.6	GO:0021670	lateral ventricle development(GO:0021670)
0.1	0.4	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.1	0.4	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.1	0.2	GO:0015755	fructose transport(GO:0015755)
0.1	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.1	0.3	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.1	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.2	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1	0.2	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.1	0.1	GO:0042706	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.1	0.2	GO:1903416	response to glycoside(GO:1903416)
0.1	0.1	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.1	0.2	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	0.2	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.4	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.4	GO:0051451	myoblast migration(GO:0051451)
0.1	0.3	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.1	1.1	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.2	GO:0002468	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.2	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.1	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0	0.2	GO:0060058	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.2	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.4	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.2	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.2	GO:0070836	caveola assembly(GO:0070836)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.0	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0	1.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0071655	macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0	0.2	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.2	GO:0072017	distal tubule development(GO:0072017)
0.0	0.2	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.1	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.3	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.3	GO:0000012	single strand break repair(GO:0000012)
0.0	0.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.4	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.4	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.1	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.1	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.1	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.5	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.1	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.1	GO:0071899	regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.1	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.3	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0072038	mesenchymal stem cell maintenance involved in nephron morphogenesis(GO:0072038)
0.0	0.9	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.3	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.0	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0	0.1	GO:1904180	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.1	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.2	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.0	0.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.0	GO:0003140	determination of left/right asymmetry in lateral mesoderm(GO:0003140) nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0	0.1	GO:2001055	positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.0	0.1	GO:0061046	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.0	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0	0.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.1	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.1	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.1	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0006868	glutamine transport(GO:0006868)
0.0	0.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.1	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.2	GO:0070932	histone H3 deacetylation(GO:0070932)
0.0	0.4	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.2	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.2	GO:1904869	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0	0.1	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.5	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.0	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.4	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.1	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.0	GO:0050883	cerebellum maturation(GO:0021590) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.1	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.2	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.2	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.2	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.1	GO:0043308	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0034350	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0	0.1	GO:0021871	forebrain regionalization(GO:0021871)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.1	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.0	1.2	GO:0003341	cilium movement(GO:0003341)
0.0	0.1	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.0	GO:0021855	hypothalamus cell migration(GO:0021855)
0.0	0.4	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:2000726	negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.1	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.5	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.0	0.0	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.0	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.1	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0	0.0	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	0.1	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
0.0	0.1	GO:0045655	regulation of monocyte differentiation(GO:0045655) positive regulation of monocyte differentiation(GO:0045657)
0.0	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.0	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
0.0	0.1	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.1	GO:0033504	floor plate development(GO:0033504)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.2	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.0	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.0	0.2	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.2	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0	0.0	GO:0070350	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.0	GO:0060026	convergent extension(GO:0060026)
0.0	0.0	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.0	0.2	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0061355	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.1	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.1	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0	0.2	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.0	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.0	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.0	0.1	GO:0010446	response to alkaline pH(GO:0010446)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.4	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.0	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.0	0.0	GO:0061043	regulation of vascular wound healing(GO:0061043)
0.0	0.1	GO:0010624	regulation of Schwann cell proliferation(GO:0010624)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.2	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.8	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	0.4	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.0	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.0	0.1	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.5	GO:1903845	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.0	0.0	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	0.0	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.2	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.5	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.0	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.0	GO:0060439	trachea morphogenesis(GO:0060439)
0.0	0.1	GO:0060770	epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0043397	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0	0.0	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.0	GO:0003160	endocardium morphogenesis(GO:0003160)
0.0	0.0	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.2	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	1.0	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.2	GO:0001967	suckling behavior(GO:0001967)
0.0	0.2	GO:0006921	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0	0.1	GO:1902946	protein localization to early endosome(GO:1902946)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0048769	sarcomerogenesis(GO:0048769)
0.0	0.0	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.0	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.7	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.0	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.4	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.0	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.2	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	0.0	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0042525	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.2	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0030578	PML body organization(GO:0030578)
0.0	0.6	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.0	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.0	0.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.1	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:0072160	nephron tubule epithelial cell differentiation(GO:0072160)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.1	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.0	GO:0060161	positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0001709	cell fate determination(GO:0001709)
0.0	0.0	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.1	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0	0.0	GO:0035697	CD8-positive, alpha-beta T cell extravasation(GO:0035697) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0	0.2	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.0	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.0	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.0	GO:0061511	centriole elongation(GO:0061511)
0.0	0.4	GO:0035113	embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0	0.0	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.0	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.0	0.1	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.0	GO:0002584	negative regulation of antigen processing and presentation(GO:0002578) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.2	GO:1903427	negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0	0.4	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.5	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.4	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.0	GO:0043970	histone H3-K9 acetylation(GO:0043970)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.3	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.1	GO:0001765	membrane raft assembly(GO:0001765)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090)
0.0	0.2	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0001825	blastocyst formation(GO:0001825)
0.0	0.0	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.0	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.1	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.0	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.0	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.1	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.0	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.0	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.0	GO:0035927	RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
0.0	0.0	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.0	0.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.0	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.0	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.1	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.1	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070552	BRISC complex(GO:0070552)
0.1	0.4	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.7	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	0.3	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.3	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.3	GO:1990246	uniplex complex(GO:1990246)
0.1	0.3	GO:0097422	tubular endosome(GO:0097422)
0.1	0.2	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.2	GO:0071953	elastic fiber(GO:0071953)
0.1	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.5	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.4	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.2	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	1.3	GO:0008305	integrin complex(GO:0008305)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.3	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.3	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.3	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.3	GO:0060091	kinocilium(GO:0060091)
0.0	0.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0070847	core mediator complex(GO:0070847)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.3	GO:0016460	myosin II complex(GO:0016460)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:0033010	paranodal junction(GO:0033010)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.3	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.0	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.0	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.2	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.0	GO:0036396	MIS complex(GO:0036396)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.0	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	1.0	GO:0005884	actin filament(GO:0005884)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.0	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:1904949	ATPase complex(GO:1904949)
0.0	0.1	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.0	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.0	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.8	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.0	GO:1990357	terminal web(GO:1990357)
0.0	0.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.2	0.5	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2	0.8	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	0.9	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.4	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	0.4	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.3	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	0.3	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.6	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	2.0	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.7	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.3	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.3	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.3	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.2	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.2	GO:0031433	telethonin binding(GO:0031433)
0.1	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.2	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	0.1	GO:0043199	sulfate binding(GO:0043199)
0.1	0.2	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.7	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.2	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.2	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.2	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	1.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0005113	patched binding(GO:0005113)
0.0	0.3	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.4	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.2	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.0	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.2	GO:0034784	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0	0.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.3	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
0.0	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.4	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
0.0	0.1	GO:0036122	BMP binding(GO:0036122)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.0	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	1.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.9	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.6	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.3	GO:0000987	core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0	0.1	GO:0003916	DNA topoisomerase activity(GO:0003916)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.4	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.0	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.3	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.1	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.0	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0008147	structural constituent of bone(GO:0008147)
0.0	0.0	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.5	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.5	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.7	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0001164	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0008193	tRNA guanylyltransferase activity(GO:0008193)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	1.8	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.0	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.0	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.0	GO:0042731	PH domain binding(GO:0042731)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	3.4	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.5	GO:0016875	ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0055102	lipase inhibitor activity(GO:0055102)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.2	GO:0008579	JUN kinase phosphatase activity(GO:0008579) phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.0	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.0	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.0	GO:0051870	methotrexate binding(GO:0051870)
0.0	0.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	2.1	PID BMP PATHWAY	BMP receptor signaling
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	1.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.8	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.6	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	0.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.7	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.6	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	1.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR

Results for Irx4

Z-value: 0.94

Motif logo

Transcription factors associated with Irx4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Irx4 motif across conditions

Conditions sorted by the z-value of the Irx4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: