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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Klf3

Z-value: 0.58

Motif logo

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Transcription factors associated with Klf3

Gene Symbol Gene ID Gene Info
Klf3
ENSMUSG00000029178.8 Kruppel-like factor 3 (basic)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_64809367_64809770Klf327710.2072710.292.4e-02Click!
chr5_64802596_64803261Klf34600.576944-0.264.9e-02Click!
chr5_64809804_64809955Klf324600.2241550.255.1e-02Click!
chr5_64813848_64814093Klf315860.3226680.247.0e-02Click!
chr5_64781139_64781290Klf3221740.1339050.142.7e-01Click!

Activity of the Klf3 motif across conditions

Conditions sorted by the z-value of the Klf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_102360845_102363484 1.22 Slc4a1
 solute carrier family 4 (anion exchanger), member 1
 1540
 0.24
chr4_155893812_155895517 1.20 Acap3
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
 2352
 0.11
chr11_90677181_90677343 1.16 Tom1l1
 target of myb1-like 1 (chicken)
 10317
 0.2
chr18_67573133_67573367 1.05 Gm17669
 predicted gene, 17669
 10856
 0.17
chr16_23058440_23059079 0.99 Kng1
 kininogen 1
 366
 0.69
chr2_74713120_74713846 0.91 Hoxd3os1
 homeobox D3, opposite strand 1
 957
 0.21
chr17_56241459_56242409 0.77 A230051N06Rik
 RIKEN cDNA A230051N06 gene
 218
 0.81
chr7_45047563_45050465 0.76 Prr12
 proline rich 12
 3867
 0.07
chr19_47017426_47018238 0.75 Nt5c2
 5'-nucleotidase, cytosolic II
 2679
 0.17
chr17_48450856_48451498 0.75 Tspo2
 translocator protein 2
 315
 0.83
chr14_66344363_66345813 0.72 Stmn4
 stathmin-like 4
 707
 0.65
chr10_127167223_127168270 0.69 B4galnt1
 beta-1,4-N-acetyl-galactosaminyl transferase 1
 1887
 0.15
chr11_102364387_102365146 0.67 Slc4a1
 solute carrier family 4 (anion exchanger), member 1
 481
 0.67
chr6_90551160_90552107 0.64 Aldh1l1
 aldehyde dehydrogenase 1 family, member L1
 785
 0.56
chr17_48272521_48272834 0.63 Treml4
 triggering receptor expressed on myeloid cells-like 4
 238
 0.88
chr6_52229552_52230397 0.61 Mir196b
 microRNA 196b
 191
 0.57
chr7_79502506_79503035 0.61 Mir9-3
 microRNA 9-3
 2494
 0.13
chr2_27981777_27982295 0.61 Col5a1
 collagen, type V, alpha 1
 35405
 0.15
chr1_130732649_130733832 0.60 AA986860
 expressed sequence AA986860
 1130
 0.29
chr1_172894740_172894971 0.59 Apcs
 serum amyloid P-component
 186
 0.93
chr17_88460455_88460676 0.57 Foxn2
 forkhead box N2
 19790
 0.17
chr1_74949307_74952042 0.56 Ihh
 Indian hedgehog
 768
 0.5
chr19_5842574_5845856 0.56 Neat1
 nuclear paraspeckle assembly transcript 1 (non-protein coding)
 1044
 0.25
chr11_6413239_6413536 0.56 Ppia
 peptidylprolyl isomerase A
 2056
 0.17
chr7_101422402_101423202 0.55 Pde2a
 phosphodiesterase 2A, cGMP-stimulated
 956
 0.45
chr13_54607077_54607512 0.55 Cltb
 clathrin, light polypeptide (Lcb)
 3998
 0.12
chr5_139382341_139382984 0.54 Gpr146
 G protein-coupled receptor 146
 2081
 0.2
chr7_27448641_27448983 0.53 Blvrb
 biliverdin reductase B (flavin reductase (NADPH))
 751
 0.39
chrX_7640827_7641363 0.53 Syp
 synaptophysin
 1334
 0.21
chr6_83068298_83071797 0.52 Tlx2
 T cell leukemia, homeobox 2
 178
 0.81
chr7_126702563_126704731 0.51 Coro1a
 coronin, actin binding protein 1A
 473
 0.55
chr16_42275550_42276525 0.50 Gap43
 growth associated protein 43
 35
 0.98
chr5_123150083_123151176 0.50 Setd1b
 SET domain containing 1B
 7672
 0.08
chr17_85686512_85689764 0.49 Six2
 sine oculis-related homeobox 2
 116
 0.96
chr5_124451141_124451723 0.49 Kmt5a
 lysine methyltransferase 5A
 261
 0.84
chr7_19022230_19023942 0.49 Foxa3
 forkhead box A3
 452
 0.57
chr2_127362687_127364202 0.49 Adra2b
 adrenergic receptor, alpha 2b
 158
 0.94
chr13_43261355_43261506 0.48 Gfod1
 glucose-fructose oxidoreductase domain containing 1
 41975
 0.15
chr17_78248797_78249192 0.48 Crim1
 cysteine rich transmembrane BMP regulator 1 (chordin like)
 11222
 0.18
chr15_100402856_100403333 0.47 Slc11a2
 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
 149
 0.92
chr5_112345255_112345758 0.47 Hps4
 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
 2406
 0.14
chr19_7421074_7423945 0.47 Mir6991
 microRNA 6991
 64
 0.94
chr17_12378732_12379615 0.46 Plg
 plasminogen
 514
 0.75
chr15_102976255_102978005 0.46 Hoxc9
 homeobox C9
 98
 0.92
chr13_21776625_21776982 0.44 H1f5
 H1.5 linker histone, cluster member
 3822
 0.06
chr4_152349775_152350796 0.44 Gm13645
 predicted gene 13645
 3356
 0.16
chr9_74865733_74868961 0.44 Onecut1
 one cut domain, family member 1
 863
 0.54
chr3_66486206_66486617 0.44 Gm17952
 predicted gene, 17952
 77140
 0.1
chr19_6398611_6400187 0.44 Rasgrp2
 RAS, guanyl releasing protein 2
 57
 0.93
chr2_24951893_24952139 0.43 Zmynd19
 zinc finger, MYND domain containing 19
 1806
 0.16
chr17_27183697_27183996 0.43 Lemd2
 LEM domain containing 2
 9634
 0.1
chrX_74426690_74427045 0.43 Ikbkg
 inhibitor of kappaB kinase gamma
 1035
 0.31
chr16_91219818_91221532 0.42 Gm49614
 predicted gene, 49614
 2251
 0.2
chr5_73246539_73246690 0.41 Fryl
 FRY like transcription coactivator
 9811
 0.11
chr7_25674373_25675380 0.41 Tmem91
 transmembrane protein 91
 171
 0.89
chr10_81024569_81025640 0.41 Gm16099
 predicted gene 16099
 21
 0.8
chr10_81091601_81092278 0.41 Creb3l3
 cAMP responsive element binding protein 3-like 3
 33
 0.94
chr2_102867441_102867713 0.41 Gm23731
 predicted gene, 23731
 30383
 0.18
chr7_49398916_49399175 0.40 Nav2
 neuron navigator 2
 34324
 0.18
chr5_22341020_22341652 0.40 Reln
 reelin
 3354
 0.18
chr11_17007546_17008653 0.40 Plek
 pleckstrin
 603
 0.7
chr4_125122525_125123430 0.40 Zc3h12a
 zinc finger CCCH type containing 12A
 457
 0.77
chr15_75892413_75892732 0.40 Naprt
 nicotinate phosphoribosyltransferase
 4
 0.94
chr11_84520959_84524590 0.40 Lhx1
 LIM homeobox protein 1
 63
 0.97
chr18_64265796_64267074 0.39 St8sia3
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
 47
 0.97
chr8_71700550_71701837 0.39 B3gnt3
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
 596
 0.52
chr16_49775252_49775761 0.39 Gm15518
 predicted gene 15518
 23364
 0.2
chr5_139211825_139211976 0.39 Sun1
 Sad1 and UNC84 domain containing 1
 41
 0.97
chr11_77783639_77784980 0.39 Gm10277
 predicted gene 10277
 3438
 0.18
chr8_123410787_123412789 0.38 Tubb3
 tubulin, beta 3 class III
 198
 0.84
chr1_166130460_166130958 0.37 Gpa33
 glycoprotein A33 (transmembrane)
 242
 0.91
chr2_121357946_121359451 0.37 Ckmt1
 creatine kinase, mitochondrial 1, ubiquitous
 32
 0.95
chr10_95880189_95880470 0.36 Gm47724
 predicted gene, 47724
 9530
 0.13
chr1_63655959_63656110 0.36 Gm12748
 predicted gene 12748
 15434
 0.15
chr1_132384306_132384539 0.36 Gm15849
 predicted gene 15849
 3293
 0.17
chr7_16275527_16275803 0.36 Ccdc9
 coiled-coil domain containing 9
 106
 0.93
chr6_108659051_108660392 0.36 Bhlhe40
 basic helix-loop-helix family, member e40
 908
 0.41
chr9_44396453_44399065 0.35 Slc37a4
 solute carrier family 37 (glucose-6-phosphate transporter), member 4
 417
 0.53
chr7_98493200_98493540 0.35 Lrrc32
 leucine rich repeat containing 32
 852
 0.49
chr3_8509825_8511666 0.35 Stmn2
 stathmin-like 2
 1159
 0.54
chr12_101026829_101027420 0.35 Ccdc88c
 coiled-coil domain containing 88C
 1785
 0.23
chr10_128400690_128401219 0.35 Slc39a5
 solute carrier family 39 (metal ion transporter), member 5
 256
 0.73
chr1_177411902_177412443 0.35 Gm26801
 predicted gene, 26801
 16912
 0.17
chr5_130022581_130023074 0.35 Asl
 argininosuccinate lyase
 1473
 0.28
chr11_99176689_99176840 0.35 Ccr7
 chemokine (C-C motif) receptor 7
 21687
 0.13
chr13_112043719_112044107 0.35 Gm15323
 predicted gene 15323
 38411
 0.15
chr2_26576075_26576641 0.34 Egfl7
 EGF-like domain 7
 3656
 0.11
chr7_46396141_46398423 0.34 Kcnc1
 potassium voltage gated channel, Shaw-related subfamily, member 1
 366
 0.84
chr4_155162564_155162715 0.34 Ski
 ski sarcoma viral oncogene homolog (avian)
 25657
 0.14
chr2_153345876_153347096 0.34 2500004C02Rik
 RIKEN cDNA 2500004C02 gene
 413
 0.6
chr19_45230983_45235468 0.34 Lbx1
 ladybird homeobox 1
 2587
 0.27
chr11_96308497_96309471 0.34 Hoxb5os
 homeobox B5 and homeobox B6, opposite strand
 2074
 0.12
chr4_62479845_62481162 0.33 Bspry
 B-box and SPRY domain containing
 414
 0.75
chr1_120598097_120600876 0.33 En1
 engrailed 1
 2932
 0.29
chr10_80879874_80880283 0.33 Tmprss9
 transmembrane protease, serine 9
 358
 0.72
chr2_70921160_70921456 0.33 Gm13632
 predicted gene 13632
 43479
 0.14
chr10_49779879_49781120 0.33 Grik2
 glutamate receptor, ionotropic, kainate 2 (beta 2)
 2760
 0.23
chr3_51518589_51518921 0.33 Setd7
 SET domain containing (lysine methyltransferase) 7
 17892
 0.09
chr2_152085191_152085589 0.32 Scrt2
 scratch family zinc finger 2
 3861
 0.17
chr8_121590486_121591687 0.32 Map1lc3b
 microtubule-associated protein 1 light chain 3 beta
 374
 0.77
chr16_93366361_93366682 0.32 1810053B23Rik
 RIKEN cDNA 1810053B23 gene
 147
 0.94
chr7_30531338_30531929 0.32 Arhgap33
 Rho GTPase activating protein 33
 1768
 0.12
chr6_143832506_143833713 0.32 Sox5
 SRY (sex determining region Y)-box 5
 113979
 0.06
chr5_123222744_123223261 0.31 Psmd9
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
 5188
 0.12
chr12_16632574_16632725 0.31 Lpin1
 lipin 1
 14317
 0.17
chr7_19082814_19086200 0.31 Dmpk
 dystrophia myotonica-protein kinase
 203
 0.83
chr8_106336310_106337932 0.31 Smpd3
 sphingomyelin phosphodiesterase 3, neutral
 867
 0.61
chr19_8709801_8709987 0.31 Slc3a2
 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
 3091
 0.07
chr11_83850990_83852424 0.30 Hnf1b
 HNF1 homeobox B
 535
 0.69
chr4_130171697_130173536 0.30 Tinagl1
 tubulointerstitial nephritis antigen-like 1
 2075
 0.27
chr1_89467693_89468170 0.30 Agap1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 12675
 0.19
chr3_146101204_146101488 0.29 Wdr63
 WD repeat domain 63
 6784
 0.16
chr4_140584429_140584695 0.29 Arhgef10l
 Rho guanine nucleotide exchange factor (GEF) 10-like
 219
 0.94
chr14_54408224_54410842 0.29 Slc7a7
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
 73
 0.94
chr13_110094155_110094306 0.29 Pde4d
 phosphodiesterase 4D, cAMP specific
 158918
 0.04
chr17_36019108_36019278 0.29 H2-T24
 histocompatibility 2, T region locus 24
 1332
 0.17
chr7_24369840_24369991 0.29 Kcnn4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
 348
 0.74
chr9_41156579_41157745 0.28 Ubash3b
 ubiquitin associated and SH3 domain containing, B
 340
 0.82
chr6_136547141_136547342 0.28 Atf7ip
 activating transcription factor 7 interacting protein
 3946
 0.19
chr5_88564689_88565985 0.28 Rufy3
 RUN and FYVE domain containing 3
 297
 0.87
chr10_17651311_17651462 0.28 Gm47771
 predicted gene, 47771
 7127
 0.25
chrX_161719845_161720465 0.28 Rai2
 retinoic acid induced 2
 2528
 0.41
chr2_74692311_74693685 0.28 Hoxd10
 homeobox D10
 1074
 0.19
chr11_16503427_16503928 0.28 Sec61g
 SEC61, gamma subunit
 1367
 0.46
chr7_142474634_142476734 0.28 Lsp1
 lymphocyte specific 1
 690
 0.52
chr2_31638722_31641540 0.27 Prdm12
 PR domain containing 12
 94
 0.84
chr10_81145829_81146966 0.27 Zbtb7a
 zinc finger and BTB domain containing 7a
 8444
 0.07
chr14_32600761_32600912 0.27 Prrxl1
 paired related homeobox protein-like 1
 878
 0.56
chr2_158401974_158402125 0.27 Gm14201
 predicted gene 14201
 966
 0.34
chr15_8967409_8968940 0.27 Ranbp3l
 RAN binding protein 3-like
 172
 0.96
chr9_22049418_22049658 0.27 Elavl3
 ELAV like RNA binding protein 3
 2472
 0.12
chr11_84519041_84519440 0.27 Lhx1
 LIM homeobox protein 1
 2827
 0.25
chr2_66632905_66633478 0.27 Scn9a
 sodium channel, voltage-gated, type IX, alpha
 1462
 0.53
chr16_31754278_31755029 0.27 Dlg1
 discs large MAGUK scaffold protein 1
 303
 0.86
chr5_123201326_123201494 0.27 Gm43409
 predicted gene 43409
 9822
 0.1
chr1_152807871_152808731 0.26 Ncf2
 neutrophil cytosolic factor 2
 323
 0.86
chr11_61075424_61076210 0.26 Kcnj12
 potassium inwardly-rectifying channel, subfamily J, member 12
 10013
 0.17
chr17_28237484_28238264 0.26 Ppard
 peroxisome proliferator activator receptor delta
 5067
 0.12
chr3_89386729_89388779 0.26 Zbtb7b
 zinc finger and BTB domain containing 7B
 83
 0.91
chr7_35553510_35553693 0.26 Nudt19
 nudix (nucleoside diphosphate linked moiety X)-type motif 19
 1558
 0.24
chr2_155992156_155992465 0.26 Cep250
 centrosomal protein 250
 6395
 0.11
chr7_144238658_144240098 0.26 Shank2
 SH3 and multiple ankyrin repeat domains 2
 653
 0.8
chr2_174283563_174287177 0.26 Gnas
 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
 12
 0.53
chr11_77892631_77894065 0.26 Pipox
 pipecolic acid oxidase
 748
 0.58
chr6_118757785_118758013 0.26 Cacna1c
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 75
 0.98
chr14_70106795_70107014 0.25 Bin3
 bridging integrator 3
 6739
 0.15
chrX_48204804_48205976 0.25 Zdhhc9
 zinc finger, DHHC domain containing 9
 2938
 0.23
chr1_75212400_75213683 0.25 Stk16
 serine/threonine kinase 16
 20
 0.92
chr11_74555781_74555954 0.25 Rap1gap2
 RAP1 GTPase activating protein 2
 33116
 0.15
chr9_45202291_45202442 0.25 Tmprss4
 transmembrane protease, serine 4
 1620
 0.23
chr10_39736016_39736307 0.25 Rev3l
 REV3 like, DNA directed polymerase zeta catalytic subunit
 3797
 0.16
chr7_25152042_25153378 0.25 D930028M14Rik
 RIKEN cDNA D930028M14 gene
 253
 0.87
chr1_130731543_130732516 0.25 AA986860
 expressed sequence AA986860
 53
 0.94
chr18_74733826_74734119 0.25 Myo5b
 myosin VB
 207
 0.94
chr6_60827248_60827682 0.25 Snca
 synuclein, alpha
 91
 0.97
chr2_25459014_25459284 0.25 Paxx
 non-homologous end joining factor
 1051
 0.23
chr11_104234777_104235157 0.25 Mapt
 microtubule-associated protein tau
 3383
 0.19
chr5_64159427_64160996 0.25 Tbc1d1
 TBC1 domain family, member 1
 0
 0.97
chr17_78290191_78290620 0.24 Crim1
 cysteine rich transmembrane BMP regulator 1 (chordin like)
 10222
 0.18
chr4_119027493_119027644 0.24 Gm12862
 predicted gene 12862
 27083
 0.08
chr18_82489298_82489862 0.24 Mbp
 myelin basic protein
 14210
 0.17
chr4_125488664_125489133 0.24 Grik3
 glutamate receptor, ionotropic, kainate 3
 1802
 0.36
chr17_49436615_49437040 0.24 Mocs1
 molybdenum cofactor synthesis 1
 3631
 0.26
chr18_83192582_83193531 0.24 1700095A13Rik
 RIKEN cDNA 1700095A13 gene
 85166
 0.08
chr15_80190031_80190182 0.24 Mgat3
 mannoside acetylglucosaminyltransferase 3
 16385
 0.11
chr7_24370279_24371432 0.24 Kcnn4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
 517
 0.59
chr1_167375050_167375216 0.24 Aldh9a1
 aldehyde dehydrogenase 9, subfamily A1
 10967
 0.13
chr12_4873247_4874779 0.24 Mfsd2b
 major facilitator superfamily domain containing 2B
 332
 0.82
chr3_96576165_96577539 0.24 Gm16253
 predicted gene 16253
 132
 0.89
chr2_158308324_158308475 0.24 Lbp
 lipopolysaccharide binding protein
 1787
 0.24
chr6_113282134_113283787 0.24 Cpne9
 copine family member IX
 595
 0.55
chr15_102981032_102982455 0.24 Hoxc9
 homeobox C9
 4711
 0.09
chr3_87913699_87914234 0.23 Hdgf
 heparin binding growth factor
 5
 0.95
chr12_102355566_102356003 0.23 Rin3
 Ras and Rab interactor 3
 1004
 0.59
chr14_34623313_34624132 0.23 Opn4
 opsin 4 (melanopsin)
 23580
 0.11
chr9_120481695_120481846 0.23 Eif1b
 eukaryotic translation initiation factor 1B
 10462
 0.14
chr14_56100230_56100381 0.23 Ctsg
 cathepsin G
 1470
 0.21
chr19_4058692_4059651 0.23 Gstp3
 glutathione S-transferase pi 3
 124
 0.88
chr16_18418352_18418503 0.23 Gm15764
 predicted gene 15764
 1542
 0.24
chr4_140244024_140245271 0.23 Igsf21
 immunoglobulin superfamily, member 21
 2137
 0.36
chr3_89138382_89138543 0.23 Pklr
 pyruvate kinase liver and red blood cell
 1839
 0.14
chr4_46391513_46391664 0.23 Trmo
 tRNA methyltransferase O
 2151
 0.22
chr2_181767278_181768191 0.23 Myt1
 myelin transcription factor 1
 222
 0.91
chr12_13180179_13180570 0.23 Gm24208
 predicted gene, 24208
 16611
 0.16
chr2_20736484_20738247 0.23 Etl4
 enhancer trap locus 4
 51
 0.98
chr1_136445067_136445535 0.23 Ddx59
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
 12899
 0.14
chr10_12963484_12964773 0.23 Stx11
 syntaxin 11
 130
 0.96
chr11_117946846_117947224 0.23 Socs3
 suppressor of cytokine signaling 3
 22151
 0.11
chr3_57426561_57426712 0.22 Tm4sf4
 transmembrane 4 superfamily member 4
 1322
 0.5
chr16_30387562_30389582 0.22 Atp13a3
 ATPase type 13A3
 42
 0.98
chrX_137118132_137120673 0.22 Esx1
 extraembryonic, spermatogenesis, homeobox 1
 769
 0.36
chr11_97511052_97512791 0.22 Gm11611
 predicted gene 11611
 9974
 0.12
chr1_132365874_132366736 0.22 Tmcc2
 transmembrane and coiled-coil domains 2
 767
 0.54
chr1_194676054_194676333 0.22 Gm38036
 predicted gene, 38036
 809
 0.58
chr1_42707054_42709031 0.22 Pantr2
 POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2
 10
 0.97
chr18_23807443_23808685 0.22 Mapre2
 microtubule-associated protein, RP/EB family, member 2
 3961
 0.2
chr10_42533045_42533196 0.22 Snx3
 sorting nexin 3
 30830
 0.14
chr5_140614430_140614581 0.22 Lfng
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 2820
 0.18
chr16_97658836_97658987 0.22 Tmprss2
 transmembrane protease, serine 2
 47716
 0.14
chr10_44011393_44011544 0.22 Crybg1
 crystallin beta-gamma domain containing 1
 7099
 0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.2 0.6 GO:0072050 S-shaped body morphogenesis(GO:0072050)
0.2 0.6 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.3 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.1 0.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.4 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:0097503 sialylation(GO:0097503)
0.1 0.3 GO:1902075 cellular response to salt(GO:1902075)
0.1 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.4 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.3 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.1 0.2 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:1900211 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.1 0.4 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.1 0.2 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.5 GO:0043173 nucleotide salvage(GO:0043173)
0.1 0.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.3 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:0043320 natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.2 GO:0010046 response to mycotoxin(GO:0010046)
0.1 0.2 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.1 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.2 GO:0043622 cortical microtubule organization(GO:0043622)
0.1 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:0070268 cornification(GO:0070268)
0.1 0.2 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 0.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.8 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.3 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0010288 response to lead ion(GO:0010288)
0.0 0.3 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.0 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.0 0.1 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.1 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.1 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.4 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 1.0 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0097466 glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0 0.2 GO:0002591 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.4 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.2 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.0 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0010513 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.0 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0007614 short-term memory(GO:0007614)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.0 0.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0022615 protein to membrane docking(GO:0022615)
0.0 0.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.0 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0 0.0 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.0 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.0 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.0 GO:0043096 purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0051938 L-glutamate import(GO:0051938)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.1 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.0 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.1 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:1903859 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.0 GO:0071873 response to norepinephrine(GO:0071873)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 2.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.0 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.0 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.4 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.4 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.2 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.8 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.4 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0019767 IgE receptor activity(GO:0019767)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.0 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.0 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0034784 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.0 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0052717 N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)