Project

ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Mecom

Z-value: 0.87

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Transcription factors associated with Mecom

Gene Symbol	Gene ID	Gene Info
Mecom Ensembl NCBI MGI UniProt	ENSMUSG00000027684.10	Mecom

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Mecom	chr3_29968672_29968833	28911	0.155077	0.34	8.5e-03	Click!
Mecom	chr3_30247202_30247388	8976	0.164604	0.33	1.1e-02	Click!
Mecom	chr3_30007396_30007925	3779	0.237591	-0.29	2.2e-02	Click!
Mecom	chr3_30006216_30006441	5111	0.219775	-0.27	3.6e-02	Click!
Mecom	chr3_30512512_30512969	2918	0.192299	-0.27	3.6e-02	Click!

Activity of the Mecom motif across conditions

Conditions sorted by the z-value of the Mecom motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_45887181_45888227	2.20	Pdlim3	PDZ and LIM domain 3	2184	0.22
chr2_76981844_76982498	2.00	Ttn	titin	284	0.93
chr16_4520955_4521652	1.87	Srl	sarcalumenin	1760	0.3
chr19_36117589_36118325	1.80	Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	1953	0.34
chr13_30521440_30521935	1.77	Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	23675	0.22
chr14_41104910_41105574	1.75	Mat1a	methionine adenosyltransferase I, alpha	91	0.95
chr3_41522196_41522994	1.69	2400006E01Rik	RIKEN cDNA 2400006E01 gene	622	0.65
chr8_48920957_48921275	1.64	Gm25830	predicted gene, 25830	37365	0.18
chr1_87573319_87573846	1.57	Ngef	neuronal guanine nucleotide exchange factor	288	0.62
chr16_38361999_38362192	1.51	Popdc2	popeye domain containing 2	114	0.94
chr1_43193607_43193938	1.50	Fhl2	four and a half LIM domains 2	2989	0.23
chr7_44481287_44481705	1.46	5430431A17Rik	RIKEN cDNA 5430431A17 gene	3021	0.09
chr6_6004743_6005171	1.39	Dync1i1	dynein cytoplasmic 1 intermediate chain 1	1109	0.59
chr11_83020412_83020824	1.37	Slfn8	schlafen 8	104	0.91
chr3_129220683_129222367	1.34	Gm43697	predicted gene 43697	4003	0.19
chr8_121088119_121090419	1.33	Gm27530	predicted gene, 27530	4563	0.13
chr10_69872455_69872784	1.32	Ank3	ankyrin 3, epithelial	25512	0.26
chr19_25343674_25344266	1.31	Gm34432	predicted gene, 34432	3233	0.31
chr3_138127768_138128154	1.30	Mttp	microsomal triglyceride transfer protein	3416	0.17
chr1_181921937_181922658	1.27	Enah	ENAH actin regulator	1467	0.35
chr13_49544431_49544711	1.27	Aspn	asporin	84	0.96
chr3_117867252_117867585	1.25	Snx7	sorting nexin 7	1403	0.44
chr6_56920828_56921008	1.24	Nt5c3	5'-nucleotidase, cytosolic III	2806	0.17
chr8_126056070_126056237	1.24	Gm45876	predicted gene 45876	4371	0.23
chr9_77385312_77385845	1.19	5730403I07Rik	RIKEN cDNA 5730403I07 gene	13840	0.16
chr13_19177941_19178164	1.19	Gm31887	predicted gene, 31887	15506	0.21
chr8_24351673_24352600	1.18	Gm45164	predicted gene 45164	7300	0.22
chr12_108370973_108372659	1.15	Eml1	echinoderm microtubule associated protein like 1	859	0.58
chr5_24890083_24890395	1.15	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	1087	0.45
chr15_25364028_25365185	1.13	4930445E18Rik	RIKEN cDNA 4930445E18 gene	31947	0.14
chr8_85360708_85361016	1.13	Mylk3	myosin light chain kinase 3	4462	0.15
chr19_17328038_17328313	1.11	Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	7261	0.23
chr3_144627862_144628115	1.11	Rpl9-ps8	ribosomal protein L9, pseudogene 8	2024	0.27
chr18_69216998_69217533	1.11	Gm4402	predicted gene 4402	236	0.92
chr3_53674479_53674630	1.09	Gm6073	predicted gene 6073	7226	0.15
chr2_38164437_38165018	1.07	Dennd1a	DENN/MADD domain containing 1A	1354	0.47
chr15_74932950_74933101	1.07	Gm39556	predicted gene, 39556	3588	0.11
chr5_44307398_44307644	1.06	Gm43114	predicted gene 43114	48184	0.09
chr11_117798237_117798922	1.06	6030468B19Rik	RIKEN cDNA 6030468B19 gene	919	0.33
chr3_146700203_146700695	1.05	Gm9480	predicted gene 9480	4230	0.17
chr11_107336801_107337006	1.04	Pitpnc1	phosphatidylinositol transfer protein, cytoplasmic 1	623	0.55
chr1_135842037_135842332	1.03	Tnnt2	troponin T2, cardiac	1309	0.34
chr12_83072442_83073418	1.03	Rgs6	regulator of G-protein signaling 6	25940	0.15
chr3_116863008_116863275	1.01	Frrs1	ferric-chelate reductase 1	3574	0.16
chr8_68953760_68954364	1.00	Gm45780	predicted gene 45780	3741	0.24
chr6_49149587_49149738	1.00	Gm18010	predicted gene, 18010	23097	0.13
chr2_86314811_86314962	1.00	Olfr1053	olfactory receptor 1053	398	0.64
chr7_75595593_75596793	1.00	Akap13	A kinase (PRKA) anchor protein 13	13846	0.19
chr4_139387342_139387738	0.98	Ubr4	ubiquitin protein ligase E3 component n-recognin 4	6871	0.12
chr7_81562979_81564174	0.95	Fsd2	fibronectin type III and SPRY domain containing 2	3368	0.13
chr2_58160296_58160447	0.95	Cytip	cytohesin 1 interacting protein	124	0.96
chr4_123564242_123564871	0.94	Macf1	microtubule-actin crosslinking factor 1	138	0.96
chr5_51446665_51446816	0.91	Gm42614	predicted gene 42614	37565	0.15
chr13_9223348_9223897	0.91	Gm8784	predicted gene 8784	85	0.96
chr3_97289091_97289336	0.91	Bcl9	B cell CLL/lymphoma 9	8704	0.18
chr9_50752994_50754649	0.91	Cryab	crystallin, alpha B	574	0.54
chr2_105686247_105688467	0.90	Pax6	paired box 6	2035	0.28
chr3_35746693_35746863	0.90	Atp11b	ATPase, class VI, type 11B	7328	0.19
chr11_90726819_90728183	0.89	Tom1l1	target of myb1-like 1 (chicken)	39135	0.15
chr10_53342534_53342748	0.89	Gm47644	predicted gene, 47644	1593	0.27
chr8_13195945_13196096	0.88	Grtp1	GH regulated TBC protein 1	3765	0.12
chr5_66080287_66081072	0.87	Rbm47	RNA binding motif protein 47	305	0.84
chr3_146044950_146045559	0.87	Wdr63	WD repeat domain 63	1931	0.29
chr3_60529662_60530216	0.87	Mbnl1	muscleblind like splicing factor 1	308	0.91
chr10_108088455_108089113	0.87	Gm47999	predicted gene, 47999	53648	0.15
chr10_40629573_40630564	0.86	Ddo	D-aspartate oxidase	9	0.98
chr18_68230321_68230918	0.85	Ldlrad4	low density lipoprotein receptor class A domain containing 4	2552	0.27
chr1_107590023_107591215	0.84	Serpinb8	serine (or cysteine) peptidase inhibitor, clade B, member 8	573	0.79
chr13_73345903_73346186	0.84	Eprn	ephemeron, early developmental lncRNA	1340	0.37
chr17_44134755_44136009	0.83	Clic5	chloride intracellular channel 5	614	0.77
chr14_26441045_26441600	0.82	Slmap	sarcolemma associated protein	1333	0.39
chr19_23152215_23152476	0.82	Mir1192	microRNA 1192	2914	0.22
chr11_113799046_113799503	0.82	Sdk2	sidekick cell adhesion molecule 2	11149	0.19
chrX_159840542_159840905	0.81	Sh3kbp1	SH3-domain kinase binding protein 1	241	0.96
chr7_45574320_45575183	0.81	Bcat2	branched chain aminotransferase 2, mitochondrial	349	0.43
chr19_56389633_56389987	0.80	Nrap	nebulin-related anchoring protein	67	0.97
chr8_27061859_27062317	0.80	Plpbp	pyridoxal phosphate binding protein	11314	0.1
chr5_53469318_53470522	0.79	Rbpj	recombination signal binding protein for immunoglobulin kappa J region	3768	0.25
chr16_20424286_20424979	0.78	Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	1354	0.34
chr3_159847473_159847769	0.78	Wls	wntless WNT ligand secretion mediator	830	0.7
chr1_160987520_160988086	0.78	Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	716	0.38
chrX_160136536_160136761	0.78	Pdha1	pyruvate dehydrogenase E1 alpha 1	1661	0.46
chr8_123980288_123980565	0.78	Abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10	2696	0.15
chr16_91917498_91918270	0.78	Gm25245	predicted gene, 25245	3531	0.14
chr6_35254240_35255185	0.77	1810058I24Rik	RIKEN cDNA 1810058I24 gene	1980	0.27
chr3_84668864_84669138	0.77	Tmem154	transmembrane protein 154	2631	0.34
chr14_63234252_63234403	0.77	Gata4	GATA binding protein 4	10921	0.17
chr4_43522717_43524714	0.77	Tpm2	tropomyosin 2, beta	50	0.93
chr3_82370577_82370801	0.76	Map9	microtubule-associated protein 9	9023	0.29
chr13_52283527_52283880	0.76	Gm48199	predicted gene, 48199	103292	0.07
chr7_112742068_112742484	0.76	Tead1	TEA domain family member 1	231	0.94
chr5_122104473_122104883	0.75	Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	765	0.56
chr7_30333339_30333572	0.74	Gm50483	predicted gene, 50483	1343	0.19
chr7_16793181_16794023	0.74	Slc1a5	solute carrier family 1 (neutral amino acid transporter), member 5	425	0.73
chr18_10532272_10533276	0.73	Gm24894	predicted gene, 24894	18632	0.16
chr9_120116479_120116744	0.73	Slc25a38	solute carrier family 25, member 38	1622	0.18
chr19_5257020_5257171	0.73	Gm50189	predicted gene, 50189	1655	0.19
chr17_87638013_87638249	0.72	Epcam	epithelial cell adhesion molecule	1449	0.42
chr10_12961671_12962169	0.72	Stx11	syntaxin 11	2338	0.29
chr2_130576014_130578077	0.72	Oxt	oxytocin	872	0.39
chr5_107874374_107875235	0.72	Evi5	ecotropic viral integration site 5	240	0.86
chr11_31949668_31949862	0.72	4930524B15Rik	RIKEN cDNA 4930524B15 gene	15827	0.2
chr18_84998858_84999011	0.71	Gm50369	predicted gene, 50369	14401	0.18
chr10_84885973_84886950	0.71	Ric8b	RIC8 guanine nucleotide exchange factor B	31155	0.17
chr9_103010058_103010293	0.71	n-R5s89	nuclear encoded rRNA 5S 89	1345	0.32
chr1_135836492_135836762	0.70	Tnnt2	troponin T2, cardiac	214	0.9
chr16_97659180_97659389	0.70	Tmprss2	transmembrane protease, serine 2	48089	0.14
chr7_103915483_103915851	0.69	Olfr65	olfactory receptor 65	9325	0.06
chr3_142560872_142561094	0.69	Gbp3	guanylate binding protein 3	251	0.89
chr11_87667241_87667392	0.69	Rnf43	ring finger protein 43	2767	0.18
chr2_70838589_70839075	0.69	Tlk1	tousled-like kinase 1	13104	0.18
chr2_101624764_101625056	0.69	Rag2	recombination activating gene 2	164	0.94
chr19_43609438_43610955	0.69	Gm20467	predicted gene 20467	429	0.71
chr16_50689310_50689541	0.68	Gm9575	predicted gene 9575	23079	0.17
chr14_54984318_54984469	0.68	Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	3025	0.08
chr16_44965326_44965477	0.67	Cd200r3	CD200 receptor 3	147	0.97
chr15_36280712_36280964	0.67	Rnf19a	ring finger protein 19A	2260	0.2
chr9_59297388_59297539	0.67	Adpgk	ADP-dependent glucokinase	5880	0.22
chr2_128427966_128429191	0.65	Morrbid	myeloid RNA regulator of BCL2L11 induced cell death	504	0.77
chr17_48419331_48419482	0.65	Gm49893	predicted gene, 49893	2126	0.19
chr12_34473392_34473685	0.65	Hdac9	histone deacetylase 9	36231	0.23
chr3_71563880_71564444	0.65	Gm38305	predicted gene, 38305	98493	0.08
chr2_84944401_84944615	0.65	Slc43a3	solute carrier family 43, member 3	7618	0.13
chr7_44350602_44354420	0.65	Shank1	SH3 and multiple ankyrin repeat domains 1	1749	0.15
chr18_37694128_37695315	0.65	Pcdhga5	protocadherin gamma subfamily A, 5	341	0.59
chr10_3395166_3395468	0.65	Ppp1r14c	protein phosphatase 1, regulatory inhibitor subunit 14C	28773	0.17
chr18_78817794_78818013	0.65	Gm23895	predicted gene, 23895	169775	0.03
chr15_67114976_67115726	0.64	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	1359	0.54
chr10_111168463_111168874	0.64	Osbpl8	oxysterol binding protein-like 8	3866	0.17
chr8_28257674_28257825	0.64	Gm8100	predicted gene 8100	71909	0.12
chr3_87512098_87512912	0.63	Etv3	ets variant 3	12902	0.17
chr12_84180427_84180695	0.63	Gm19327	predicted gene, 19327	7245	0.11
chr1_43195232_43195467	0.63	Fhl2	four and a half LIM domains 2	1412	0.4
chr4_95871146_95871383	0.63	Fggy	FGGY carbohydrate kinase domain containing	21639	0.22
chr2_84519147_84519986	0.63	Gm13710	predicted gene 13710	11756	0.16
chr10_97566192_97567945	0.63	Lum	lumican	1940	0.32
chr2_22775095_22775607	0.62	Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	906	0.52
chr18_4995057_4995360	0.62	Svil	supervillin	272	0.95
chr7_68302525_68303434	0.62	Fam169b	family with sequence similarity 169, member B	2866	0.19
chr16_91374590_91374741	0.62	Ifnar2	interferon (alpha and beta) receptor 2	1766	0.23
chr8_60956707_60957423	0.61	Clcn3	chloride channel, voltage-sensitive 3	1832	0.3
chr15_41751298_41752572	0.61	Oxr1	oxidation resistance 1	234	0.95
chr4_109987871_109988544	0.61	Dmrta2	doublesex and mab-3 related transcription factor like family A2	10154	0.23
chr2_39325776_39326109	0.61	Vmn2r-ps2	vomeronasal 2, receptor, pseudogene 2	51836	0.11
chr1_183793942_183794202	0.61	Gm34068	predicted gene, 34068	45095	0.17
chr1_64918841_64919088	0.60	Plekhm3	pleckstrin homology domain containing, family M, member 3	9133	0.17
chr12_110695218_110696251	0.60	Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	62	0.96
chr7_49882511_49882708	0.60	Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	27537	0.2
chr3_147287952_147288173	0.60	Gm6074	predicted gene 6074	95144	0.08
chr18_39519741_39519892	0.60	Nr3c1	nuclear receptor subfamily 3, group C, member 1	395	0.9
chrX_160504591_160505378	0.59	Phka2	phosphorylase kinase alpha 2	2519	0.26
chr8_120883355_120884273	0.59	Gm26878	predicted gene, 26878	3608	0.28
chr2_163357123_163357274	0.59	Tox2	TOX high mobility group box family member 2	36820	0.11
chr12_64692630_64692817	0.59	Gm24066	predicted gene, 24066	43679	0.17
chr17_48269349_48269500	0.58	Treml4	triggering receptor expressed on myeloid cells-like 4	3015	0.16
chr6_139586816_139587911	0.58	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	126	0.96
chr9_69454872_69455904	0.58	Anxa2	annexin A2	1322	0.26
chr4_46032306_46032829	0.58	Tmod1	tropomodulin 1	6368	0.2
chr13_81690387_81690773	0.58	Polr3g	polymerase (RNA) III (DNA directed) polypeptide G	3295	0.21
chr6_21822751_21823961	0.58	Tspan12	tetraspanin 12	28472	0.16
chr8_60980850_60981283	0.58	Clcn3	chloride channel, voltage-sensitive 3	2173	0.22
chr16_32487079_32487647	0.58	Slc51a	solute carrier family 51, alpha subunit	340	0.82
chr3_108306156_108306424	0.57	Gm43099	predicted gene 43099	18409	0.08
chr10_40131516_40131699	0.57	Slc16a10	solute carrier family 16 (monocarboxylic acid transporters), member 10	10647	0.13
chr9_24762516_24762667	0.57	Tbx20	T-box 20	7089	0.2
chr5_83906513_83906664	0.56	Gm4866	predicted gene 4866	43425	0.2
chr4_123285872_123286357	0.56	Pabpc4	poly(A) binding protein, cytoplasmic 4	3019	0.13
chr5_99970736_99971131	0.56	Hnrnpd	heterogeneous nuclear ribonucleoprotein D	4546	0.16
chr6_57531398_57531878	0.56	Ppm1k	protein phosphatase 1K (PP2C domain containing)	3788	0.19
chr7_92706839_92707290	0.56	Gm45199	predicted gene 45199	291	0.86
chr2_32648870_32649298	0.56	Eng	endoglin	2091	0.13
chr4_41388141_41388689	0.56	Kif24	kinesin family member 24	16371	0.12
chr17_46451587_46451738	0.56	Gm5093	predicted gene 5093	11565	0.09
chr3_115815642_115816181	0.56	Dph5	diphthamide biosynthesis 5	71926	0.07
chr6_41535508_41535739	0.56	Trbj1-7	T cell receptor beta joining 1-7	19	0.94
chr17_26849670_26851386	0.55	Nkx2-5	NK2 homeobox 5	5519	0.11
chr10_44526709_44528700	0.55	Prdm1	PR domain containing 1, with ZNF domain	797	0.61
chr3_20153383_20154068	0.55	Gyg	glycogenin	1344	0.46
chr2_75964404_75965219	0.55	Ttc30a2	tetratricopeptide repeat domain 30A2	13359	0.15
chr12_73044500_73046647	0.55	Six1	sine oculis-related homeobox 1	282	0.92
chr9_117902271_117902429	0.54	Gm26614	predicted gene, 26614	29206	0.18
chr10_93672331_93673286	0.54	Gm8580	predicted gene 8580	6962	0.14
chr5_66115020_66115171	0.54	Rbm47	RNA binding motif protein 47	16904	0.11
chr10_98704817_98705484	0.54	Gm5427	predicted gene 5427	5440	0.32
chr3_80056247_80056720	0.54	A330069K06Rik	RIKEN cDNA A330069K06 gene	1591	0.43
chr14_40992448_40992681	0.54	Prxl2a	peroxiredoxin like 2A	10540	0.17
chr12_84922303_84922934	0.53	Gm17193	predicted gene 17193	894	0.45
chr5_134945425_134947032	0.53	Cldn4	claudin 4	706	0.44
chr6_88514706_88514857	0.53	Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	880	0.5
chr5_83352448_83352645	0.52	Tecrl	trans-2,3-enoyl-CoA reductase-like	2410	0.39
chr13_74743048_74743199	0.52	Cast	calpastatin	6077	0.21
chr9_24874511_24875131	0.52	Amd-ps6	S-adenosylmethionine decarboxylase, pseudogene 6	47476	0.12
chr3_57626342_57626493	0.52	Gm26671	predicted gene, 26671	593	0.62
chr16_34926590_34926891	0.52	Mylk	myosin, light polypeptide kinase	3602	0.23
chr13_111929026_111929215	0.52	Gm9025	predicted gene 9025	44943	0.11
chr10_33085602_33085934	0.52	Trdn	triadin	2207	0.39
chr5_149245583_149246503	0.51	Gm29264	predicted gene 29264	1639	0.19
chr3_53461338_53461793	0.51	Nhlrc3	NHL repeat containing 3	418	0.74
chr2_45034480_45035185	0.51	Zeb2	zinc finger E-box binding homeobox 2	11162	0.21
chr2_51072525_51072965	0.51	Rnd3	Rho family GTPase 3	76349	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mecom

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0048769	sarcomerogenesis(GO:0048769)
0.6	1.7	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.5	1.5	GO:0060931	sinoatrial node cell development(GO:0060931)
0.3	1.3	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.3	0.9	GO:0006533	aspartate catabolic process(GO:0006533)
0.3	0.8	GO:0016554	cytidine to uridine editing(GO:0016554)
0.3	0.8	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.3	0.8	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2	0.4	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.2	0.6	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.2	1.0	GO:0003175	tricuspid valve development(GO:0003175)
0.2	1.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.2	0.6	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.2	0.6	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.2	0.5	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.2	0.5	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2	1.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.2	0.9	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1	0.7	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.4	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.5	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1	0.4	GO:0006549	isoleucine metabolic process(GO:0006549)
0.1	0.2	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.7	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.1	0.4	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	0.3	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.3	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.2	GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1	0.1	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.4	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.3	GO:0043133	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.1	0.3	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.1	0.1	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.6	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.3	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.5	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.1	0.6	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.1	0.4	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.1	0.3	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.3	GO:0061144	alveolar secondary septum development(GO:0061144)
0.1	0.3	GO:0070673	response to interleukin-18(GO:0070673)
0.1	0.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.6	GO:0015825	L-serine transport(GO:0015825)
0.1	0.2	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.1	0.2	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.1	0.6	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.2	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.4	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	0.4	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.1	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.2	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.6	GO:0043312	neutrophil degranulation(GO:0043312)
0.1	0.2	GO:0000101	sulfur amino acid transport(GO:0000101)
0.1	0.2	GO:0061010	gall bladder development(GO:0061010)
0.1	0.3	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.3	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.8	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.1	0.2	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	0.5	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	0.5	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.3	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	0.7	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.3	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1	0.2	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.1	0.4	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1	0.2	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
0.1	0.2	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	0.2	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.1	0.3	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.3	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	0.3	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.2	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1	0.1	GO:0061511	centriole elongation(GO:0061511)
0.1	0.2	GO:0019042	viral latency(GO:0019042)
0.1	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.1	0.5	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.5	GO:0060352	cell adhesion molecule production(GO:0060352)
0.1	0.2	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.1	0.3	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.1	0.2	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1	0.3	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.2	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.2	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	0.7	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.1	0.2	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.4	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.4	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.2	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.1	GO:0045472	response to ether(GO:0045472)
0.0	0.4	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.3	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.1	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.3	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.7	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.2	GO:0046959	habituation(GO:0046959)
0.0	0.2	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.7	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.2	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0	0.2	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.2	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0001905	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0	0.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.3	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.1	GO:1905206	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.0	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.1	GO:0035822	meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.0	0.7	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.2	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0046103	inosine biosynthetic process(GO:0046103)
0.0	0.3	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.3	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.1	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.2	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.9	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.0	0.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.6	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.2	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.2	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.2	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.2	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.1	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.2	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.4	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.2	GO:0001865	NK T cell differentiation(GO:0001865)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.1	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.8	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.1	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
0.0	0.1	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.1	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0	0.4	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.0	0.3	GO:0002827	positive regulation of T-helper 1 type immune response(GO:0002827)
0.0	0.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.5	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.1	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.2	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0050904	diapedesis(GO:0050904)
0.0	0.0	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.0	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0	0.1	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.0	0.0	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.4	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0072672	neutrophil extravasation(GO:0072672)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.1	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.2	GO:0061526	acetylcholine secretion(GO:0061526)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.1	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.0	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.1	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.2	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.5	GO:0006110	regulation of glycolytic process(GO:0006110)
0.0	0.1	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0	0.1	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.2	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0	0.5	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	1.4	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.1	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.0	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.3	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.0	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.1	GO:0046135	pyrimidine ribonucleoside catabolic process(GO:0046133) pyrimidine nucleoside catabolic process(GO:0046135)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.0	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.0	0.1	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.1	GO:0010885	regulation of cholesterol storage(GO:0010885)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.7	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.0	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.0	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.0	0.1	GO:0036295	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0099624	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0	0.1	GO:0071236	cellular response to antibiotic(GO:0071236)
0.0	0.0	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.0	GO:1904193	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.0	GO:0032348	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.0	GO:1903298	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.0	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.1	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.2	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.3	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.0	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0	0.1	GO:0009068	aspartate family amino acid catabolic process(GO:0009068)
0.0	0.0	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.0	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.0	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.0	GO:0060215	primitive hemopoiesis(GO:0060215)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.2	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.0	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.1	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0	0.0	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.0	0.0	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.0	0.1	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.0	GO:0002339	B cell selection(GO:0002339)
0.0	0.0	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.5	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0052646	alditol phosphate metabolic process(GO:0052646)
0.0	0.1	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	0.2	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.2	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0072102	glomerulus morphogenesis(GO:0072102)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0040031	snRNA modification(GO:0040031)
0.0	0.0	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.0	0.1	GO:0019441	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.0	GO:0042706	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)
0.0	0.0	GO:1902659	glial cell fate determination(GO:0007403) carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0	0.2	GO:0033363	secretory granule organization(GO:0033363)
0.0	0.0	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0034616	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0	0.0	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.1	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.0	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.3	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.0	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.1	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.0	0.0	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
0.0	0.0	GO:0031034	myosin filament assembly(GO:0031034)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.0	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.0	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0035932	mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0	0.0	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.0	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.4	GO:0042073	intraciliary transport(GO:0042073)
0.0	0.0	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.0	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.0	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.0	0.0	GO:0039535	regulation of RIG-I signaling pathway(GO:0039535)
0.0	0.0	GO:0097278	complement-dependent cytotoxicity(GO:0097278)
0.0	0.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.0	GO:0021747	cochlear nucleus development(GO:0021747)
0.0	0.0	GO:0015810	aspartate transport(GO:0015810)
0.0	0.0	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.0	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.2	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0	0.0	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.2	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.0	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0044598	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.0	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.0	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
0.0	0.0	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.0	GO:0002825	regulation of T-helper 1 type immune response(GO:0002825)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.0	GO:0007386	compartment pattern specification(GO:0007386)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.5	GO:0005859	muscle myosin complex(GO:0005859)
0.2	1.6	GO:0005861	troponin complex(GO:0005861)
0.2	0.8	GO:0005927	muscle tendon junction(GO:0005927)
0.2	0.5	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.5	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.8	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.1	0.4	GO:0035363	histone locus body(GO:0035363)
0.1	0.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	0.9	GO:0031430	M band(GO:0031430)
0.1	0.8	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	0.2	GO:1990923	PET complex(GO:1990923)
0.1	0.5	GO:0001739	sex chromatin(GO:0001739)
0.1	0.5	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.2	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.1	0.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.4	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.4	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.9	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	0.3	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.2	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	0.4	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	0.4	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.8	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:0005915	zonula adherens(GO:0005915)
0.0	0.8	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0032010	phagolysosome(GO:0032010)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.8	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.2	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	2.4	GO:0031674	I band(GO:0031674)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.4	GO:0097440	apical dendrite(GO:0097440)
0.0	0.2	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.8	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:1990716	axonemal central apparatus(GO:1990716)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.0	GO:0033269	internode region of axon(GO:0033269)
0.0	0.3	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.6	GO:0030016	myofibril(GO:0030016)
0.0	0.0	GO:0016460	myosin II complex(GO:0016460)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	1.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.4	GO:0032420	stereocilium(GO:0032420)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0000802	transverse filament(GO:0000802)
0.0	1.4	GO:0042383	sarcolemma(GO:0042383)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	1.2	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.6	GO:0031985	Golgi cisterna(GO:0031985)
0.0	0.1	GO:0097422	tubular endosome(GO:0097422)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.0	GO:0000235	astral microtubule(GO:0000235)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0032982	myosin filament(GO:0032982)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.4	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0036128	CatSper complex(GO:0036128)
0.0	1.8	GO:0005938	cell cortex(GO:0005938)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	0.0	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.1	GO:0072546	ER membrane protein complex(GO:0072546)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.3	1.0	GO:0030172	troponin C binding(GO:0030172)
0.3	0.8	GO:0045503	dynein light chain binding(GO:0045503)
0.3	0.8	GO:0001069	regulatory region RNA binding(GO:0001069)
0.2	0.5	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.4	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.4	GO:0051373	FATZ binding(GO:0051373)
0.1	0.6	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	0.4	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.6	GO:1990239	steroid hormone binding(GO:1990239)
0.1	0.5	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	1.1	GO:0015922	aspartate oxidase activity(GO:0015922)
0.1	0.4	GO:0031014	troponin T binding(GO:0031014)
0.1	0.4	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.5	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	0.6	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.4	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.1	0.6	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	0.2	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.3	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.3	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.6	GO:0031432	titin binding(GO:0031432)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.6	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.2	GO:0034618	arginine binding(GO:0034618)
0.1	0.2	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.4	GO:0004977	melanocortin receptor activity(GO:0004977)
0.1	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.3	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.6	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	0.4	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.3	GO:0000146	microfilament motor activity(GO:0000146)
0.1	0.2	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	1.9	GO:0043531	ADP binding(GO:0043531)
0.1	0.3	GO:0043426	MRF binding(GO:0043426)
0.1	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.2	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.2	GO:0009374	biotin binding(GO:0009374)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0019961	interferon binding(GO:0019961)
0.1	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.2	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.4	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.2	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.3	GO:0034868	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.4	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.2	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.8	GO:0030552	cAMP binding(GO:0030552)
0.0	0.2	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.3	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.4	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.6	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.2	GO:0018499	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.4	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0043199	sulfate binding(GO:0043199)
0.0	0.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	1.8	GO:0005518	collagen binding(GO:0005518)
0.0	0.7	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.5	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.3	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.3	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.0	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	0.1	GO:0034943	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.0	GO:0097001	ceramide binding(GO:0097001)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	1.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.0	GO:0001884	pyrimidine nucleoside binding(GO:0001884)
0.0	0.0	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.1	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.3	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.0	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.0	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.3	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.0	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.2	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.0	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	0.1	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.1	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.1	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.0	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.0	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.4	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.0	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	1.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.6	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.0	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.0	0.0	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.0	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.0	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	0.3	GO:0070330	aromatase activity(GO:0070330)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.6	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.1	1.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.6	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	1.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.7	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.2	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.4	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.5	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.8	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	0.4	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	1.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.6	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	1.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism