Project

ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Msx3

Z-value: 0.90

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Transcription factors associated with Msx3

Gene Symbol	Gene ID	Gene Info
Msx3 Ensembl NCBI MGI UniProt	ENSMUSG00000025469.9	Msx3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Msx3	chr7_140060622_140060773	11608	0.084238	-0.27	3.8e-02	Click!
Msx3	chr7_140048576_140049822	110	0.924623	0.25	5.1e-02	Click!
Msx3	chr7_140047755_140048553	934	0.360646	0.21	1.1e-01	Click!
Msx3	chr7_140046752_140046903	2261	0.149192	-0.18	1.8e-01	Click!
Msx3	chr7_140047010_140047161	2003	0.165125	-0.18	1.8e-01	Click!

Activity of the Msx3 motif across conditions

Conditions sorted by the z-value of the Msx3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_33083500_33083959	3.85	Trdn	triadin	168	0.97
chr8_85361454_85361605	2.65	Mylk3	myosin light chain kinase 3	3795	0.16
chr15_40656769_40657228	2.48	Zfpm2	zinc finger protein, multitype 2	1647	0.51
chr9_79976568_79977294	2.42	Filip1	filamin A interacting protein 1	728	0.66
chr1_153330166_153330548	2.33	Lamc1	laminin, gamma 1	2429	0.26
chr10_3368375_3368998	2.33	Ppp1r14c	protein phosphatase 1, regulatory inhibitor subunit 14C	2142	0.36
chr18_43436329_43436751	2.14	Dpysl3	dihydropyrimidinase-like 3	1746	0.35
chrX_164437518_164437860	2.12	Asb11	ankyrin repeat and SOCS box-containing 11	369	0.85
chr1_187999444_187999905	2.06	Esrrg	estrogen-related receptor gamma	1806	0.42
chr10_30838379_30838546	2.04	Hey2	hairy/enhancer-of-split related with YRPW motif 2	3553	0.21
chr5_75975434_75975824	2.02	Kdr	kinase insert domain protein receptor	2829	0.25
chr14_63235525_63236294	1.99	Gata4	GATA binding protein 4	9339	0.17
chr1_140182332_140182724	1.93	Cfh	complement component factor h	752	0.73
chr7_109191327_109192334	1.92	Lmo1	LIM domain only 1	16623	0.17
chr5_138609015_138609166	1.81	Gm15497	predicted gene 15497	1649	0.2
chr15_85673548_85673944	1.79	Lncppara	long noncoding RNA near Ppara	20130	0.13
chr1_40806618_40806769	1.78	Tmem182	transmembrane protein 182	1092	0.48
chrX_138915472_138915880	1.76	Nrk	Nik related kinase	1245	0.61
chr3_19646421_19646748	1.66	Trim55	tripartite motif-containing 55	2076	0.26
chr14_59478693_59479244	1.56	Cab39l	calcium binding protein 39-like	152	0.96
chr2_143959771_143959922	1.55	Rrbp1	ribosome binding protein 1	2201	0.29
chr2_45001616_45002114	1.53	Zeb2	zinc finger E-box binding homeobox 2	21050	0.19
chr10_128178900_128179051	1.51	Rbms2	RNA binding motif, single stranded interacting protein 2	1322	0.23
chr13_29628489_29628949	1.48	Cdkal1	CDK5 regulatory subunit associated protein 1-like 1	111265	0.07
chr16_43503039_43503193	1.47	Zbtb20	zinc finger and BTB domain containing 20	498	0.85
chr16_43504464_43505047	1.45	Zbtb20	zinc finger and BTB domain containing 20	1058	0.61
chr5_75975825_75977229	1.45	Kdr	kinase insert domain protein receptor	1931	0.31
chr1_169745785_169746010	1.45	Rgs4	regulator of G-protein signaling 4	1726	0.41
chr14_57034631_57034809	1.43	B020004C17Rik	RIKEN cDNA B020004C17 gene	19586	0.15
chr10_23686915_23687430	1.42	4930520K02Rik	RIKEN cDNA 4930520K02 gene	65024	0.09
chr5_57945633_57945798	1.41	Gm42639	predicted gene 42639	673	0.56
chr13_46423537_46423785	1.39	Rbm24	RNA binding motif protein 24	1839	0.41
chr13_46420548_46420948	1.39	Rbm24	RNA binding motif protein 24	197	0.96
chr5_138608490_138608879	1.32	Zfp68	zinc finger protein 68	1627	0.2
chr2_14825138_14825659	1.31	Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	1306	0.4
chr13_83566010_83566411	1.29	Mef2c	myocyte enhancer factor 2C	6138	0.29
chr10_39165752_39166209	1.29	Ccn6	cellular communication network factor 6	2186	0.23
chr3_30009457_30010152	1.28	Mecom	MDS1 and EVI1 complex locus	1635	0.36
chr6_98525524_98525718	1.26	4930595L18Rik	RIKEN cDNA 4930595L18 gene	26486	0.26
chr2_20942943_20943436	1.26	Arhgap21	Rho GTPase activating protein 21	230	0.93
chr8_106985656_106985807	1.26	Gm22085	predicted gene, 22085	23880	0.1
chr12_60595918_60596185	1.24	Gm6068	predicted gene 6068	47813	0.16
chr16_96205810_96206739	1.20	Sh3bgr	SH3-binding domain glutamic acid-rich protein	369	0.83
chr18_37694128_37695315	1.20	Pcdhga5	protocadherin gamma subfamily A, 5	341	0.59
chr16_77502046_77502387	1.19	Mir99ahg	Mir99a and Mirlet7c-1 host gene (non-protein coding)	1832	0.24
chr13_73262153_73264451	1.18	Irx4	Iroquois homeobox 4	2805	0.22
chr14_91522550_91522701	1.17	Gm48942	predicted gene, 48942	125214	0.06
chr3_65635958_65636417	1.17	Gm38233	predicted gene, 38233	20013	0.12
chr10_93307247_93307878	1.16	Elk3	ELK3, member of ETS oncogene family	3249	0.21
chr6_14753955_14754106	1.16	Ppp1r3a	protein phosphatase 1, regulatory subunit 3A	1244	0.63
chr13_71961770_71962476	1.15	Irx1	Iroquois homeobox 1	1407	0.5
chr15_40167052_40167633	1.15	Gm33301	predicted gene, 33301	4735	0.21
chr5_102727171_102727322	1.13	Arhgap24	Rho GTPase activating protein 24	2273	0.45
chr3_16818309_16818538	1.13	Gm26485	predicted gene, 26485	4889	0.36
chr2_55439535_55439810	1.12	Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	2507	0.37
chr16_28898704_28899105	1.11	Mb21d2	Mab-21 domain containing 2	30769	0.21
chr14_49793886_49794107	1.10	Gm22989	predicted gene, 22989	5712	0.15
chr9_115096411_115096891	1.08	Osbpl10	oxysterol binding protein-like 10	7810	0.23
chr3_60530332_60531570	1.07	Mbnl1	muscleblind like splicing factor 1	1320	0.48
chr4_40851422_40852119	1.06	Gm25931	predicted gene, 25931	1368	0.21
chr13_83529350_83529841	1.06	Mef2c	myocyte enhancer factor 2C	543	0.86
chr10_96744086_96744687	1.06	Gm6859	predicted gene 6859	25442	0.15
chr1_107590023_107591215	1.05	Serpinb8	serine (or cysteine) peptidase inhibitor, clade B, member 8	573	0.79
chr5_72796212_72796844	1.05	Tec	tec protein tyrosine kinase	10508	0.15
chr12_34529024_34529175	1.04	Hdac9	histone deacetylase 9	225	0.96
chr5_116456914_116457389	1.04	Gm42853	predicted gene 42853	333	0.83
chr15_102997344_102997495	1.03	Hoxc6	homeobox C6	838	0.37
chr18_11060814_11061287	1.03	Gata6	GATA binding protein 6	2003	0.37
chr1_177199086_177199237	1.02	Gm37706	predicted gene, 37706	28299	0.14
chr1_81593421_81594539	1.00	Gm6198	predicted gene 6198	36497	0.2
chr12_66935099_66935250	1.00	Gm47989	predicted gene, 47989	7237	0.29
chr6_146500226_146500471	1.00	Itpr2	inositol 1,4,5-triphosphate receptor 2	1530	0.4
chr10_39612918_39613668	0.99	Traf3ip2	TRAF3 interacting protein 2	359	0.48
chr12_31264979_31266396	0.99	Lamb1	laminin B1	390	0.78
chr9_83664457_83665200	0.98	Gm36120	predicted gene, 36120	22697	0.17
chr8_57315271_57316273	0.98	Hand2os1	Hand2, opposite strand 1	62	0.96
chr5_147722674_147723044	0.98	Flt1	FMS-like tyrosine kinase 1	3129	0.27
chr15_18282470_18282621	0.97	4921515E04Rik	RIKEN cDNA 4921515E04 gene	22745	0.24
chr1_188002104_188003122	0.97	Esrrg	estrogen-related receptor gamma	4745	0.26
chr2_107292125_107293014	0.97	Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	1174	0.64
chr9_86438288_86439112	0.97	Ube2cbp	ubiquitin-conjugating enzyme E2C binding protein	26250	0.17
chr10_71028206_71028357	0.96	Gm48025	predicted gene, 48025	35241	0.14
chr10_128173680_128173831	0.96	Rbms2	RNA binding motif, single stranded interacting protein 2	2724	0.12
chr18_75372210_75374418	0.96	Smad7	SMAD family member 7	1600	0.41
chr3_79180505_79180656	0.95	Rapgef2	Rap guanine nucleotide exchange factor (GEF) 2	760	0.66
chr10_30845489_30845963	0.95	Hey2	hairy/enhancer-of-split related with YRPW motif 2	2925	0.24
chr18_60375901_60376327	0.93	Iigp1	interferon inducible GTPase 1	67	0.96
chr3_79144294_79146166	0.93	Rapgef2	Rap guanine nucleotide exchange factor (GEF) 2	253	0.94
chr10_115306134_115306562	0.93	Rab21	RAB21, member RAS oncogene family	9243	0.15
chr14_119602272_119602445	0.93	Gm6212	predicted gene 6212	41654	0.2
chr5_97387372_97387523	0.92	Naa11	N(alpha)-acetyltransferase 11, NatA catalytic subunit	4932	0.21
chr17_81723922_81724212	0.91	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	14310	0.27
chr9_77344708_77344864	0.91	Mlip	muscular LMNA-interacting protein	3007	0.22
chr3_9573681_9573832	0.90	Zfp704	zinc finger protein 704	8457	0.25
chr15_100635478_100635706	0.90	Smagp	small cell adhesion glycoprotein	33	0.94
chr7_48842956_48843247	0.89	Csrp3	cysteine and glycine-rich protein 3	550	0.71
chr9_67261068_67261449	0.89	Tln2	talin 2	835	0.67
chr2_104467722_104467873	0.89	Hipk3	homeodomain interacting protein kinase 3	25893	0.14
chr12_72441609_72442616	0.88	Lrrc9	leucine rich repeat containing 9	77	0.97
chr5_5261065_5262223	0.88	Cdk14	cyclin-dependent kinase 14	3665	0.25
chr10_58394969_58395625	0.88	Lims1	LIM and senescent cell antigen-like domains 1	909	0.6
chr3_76077829_76078163	0.86	Fstl5	follistatin-like 5	2413	0.35
chr10_22815720_22817074	0.86	Gm10824	predicted gene 10824	648	0.66
chr15_50870065_50870337	0.86	Trps1	transcriptional repressor GATA binding 1	12605	0.21
chrY_3871382_3871533	0.86	Gm18177	predicted gene, 18177	4471	0.13
chr4_116073957_116074118	0.85	Uqcrh	ubiquinol-cytochrome c reductase hinge protein	994	0.31
chr4_112748048_112748199	0.85	Skint10	selection and upkeep of intraepithelial T cells 10	26702	0.2
chr18_55375824_55376307	0.84	Gm37828	predicted gene, 37828	36553	0.21
chr16_85807463_85807781	0.84	Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	4509	0.26
chr18_60439220_60439471	0.84	BC023105	cDNA sequence BC023105	2420	0.24
chr1_140180086_140180415	0.83	Cfh	complement component factor h	3030	0.32
chr10_84968503_84968659	0.83	Ric8b	RIC8 guanine nucleotide exchange factor B	31188	0.19
chr17_17448568_17449744	0.82	Lix1	limb and CNS expressed 1	336	0.88
chr6_87495688_87496317	0.82	Arhgap25	Rho GTPase activating protein 25	312	0.88
chr7_98678348_98678798	0.81	Gm45132	predicted gene 45132	2074	0.24
chr1_23321078_23322043	0.81	Gm20954	predicted gene, 20954	25039	0.11
chr10_99263341_99263492	0.81	Dusp6	dual specificity phosphatase 6	185	0.9
chr10_110922562_110923038	0.80	Csrp2	cysteine and glycine-rich protein 2	2595	0.22
chr3_9947586_9947797	0.80	Gm17877	predicted gene, 17877	24310	0.16
chr3_116966712_116967946	0.80	4930455H04Rik	RIKEN cDNA 4930455H04 gene	938	0.41
chr5_124192601_124192752	0.80	Pitpnm2os2	phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 2	2231	0.19
chr10_45338438_45338763	0.80	Bves	blood vessel epicardial substance	2828	0.24
chr4_137863933_137864084	0.80	Ece1	endothelin converting enzyme 1	1711	0.38
chr3_78594754_78595081	0.80	Gm15442	predicted gene 15442	106280	0.07
chr13_9494460_9495468	0.79	Gm48871	predicted gene, 48871	49064	0.12
chr9_73967774_73969221	0.79	Unc13c	unc-13 homolog C	469	0.88
chr1_34439512_34439753	0.79	Ccdc115	coiled-coil domain containing 115	40	0.71
chr13_102957440_102958679	0.78	Mast4	microtubule associated serine/threonine kinase family member 4	287	0.95
chr6_39055880_39056082	0.78	1700025N23Rik	RIKEN cDNA 1700025N23 gene	11617	0.15
chr16_37779366_37779517	0.78	Fstl1	follistatin-like 1	2289	0.31
chr14_66147812_66148016	0.77	Chrna2	cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)	6981	0.17
chr5_14026773_14026948	0.77	Gm43519	predicted gene 43519	1034	0.45
chr15_51854353_51854609	0.77	Eif3h	eukaryotic translation initiation factor 3, subunit H	10973	0.17
chr2_67568406_67568614	0.77	B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	2639	0.3
chr7_136275874_136276030	0.77	C030029H02Rik	RIKEN cDNA C030029H02 gene	7618	0.21
chr18_47370463_47370942	0.77	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	1832	0.37
chr8_125186745_125187429	0.77	Gm16237	predicted gene 16237	40236	0.17
chr6_29351906_29352057	0.76	Calu	calumenin	3862	0.13
chr8_45901486_45902198	0.76	Pdlim3	PDZ and LIM domain 3	13190	0.12
chr1_162000010_162000265	0.76	Dnm3	dynamin 3	4123	0.16
chr13_71967461_71968595	0.76	Irx1	Iroquois homeobox 1	4305	0.28
chr4_31468474_31468780	0.75	Gm11922	predicted gene 11922	88155	0.1
chr6_16316653_16317675	0.75	Gm3148	predicted gene 3148	79537	0.1
chrX_13208320_13208567	0.75	Rpl3-ps1	ribosomal protein L3, pseudogene 1	5872	0.11
chr10_56106927_56107500	0.75	Msl3l2	MSL3 like 2	296	0.92
chr17_88597076_88597227	0.75	Ston1	stonin 1	533	0.74
chr6_94592745_94593176	0.75	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	12433	0.18
chr1_168429421_168430005	0.74	Pbx1	pre B cell leukemia homeobox 1	1791	0.44
chr13_104948155_104948442	0.73	Gm4938	predicted pseudogene 4938	29518	0.2
chr14_28533395_28533564	0.73	Wnt5a	wingless-type MMTV integration site family, member 5A	22028	0.19
chrX_159943977_159944189	0.72	Sh3kbp1	SH3-domain kinase binding protein 1	1065	0.59
chr18_24711980_24712131	0.72	Fhod3	formin homology 2 domain containing 3	2610	0.23
chr5_16630062_16630213	0.72	Gm42975	predicted gene 42975	24415	0.2
chrX_83936299_83936450	0.72	Dmd	dystrophin, muscular dystrophy	8474	0.32
chr3_42111234_42111590	0.72	Gm37846	predicted gene, 37846	52453	0.16
chr13_52528312_52528571	0.72	Diras2	DIRAS family, GTP-binding RAS-like 2	2838	0.37
chrX_142684293_142684706	0.71	Tmem164	transmembrane protein 164	1611	0.4
chr9_53850790_53851038	0.71	Sln	sarcolipin	750	0.65
chr9_56416072_56416694	0.71	Gm36940	predicted gene, 36940	317	0.81
chr13_95765042_95765602	0.71	Iqgap2	IQ motif containing GTPase activating protein 2	925	0.57
chr1_131232374_131233673	0.70	Rassf5	Ras association (RalGDS/AF-6) domain family member 5	552	0.67
chr18_61783794_61784202	0.70	Afap1l1	actin filament associated protein 1-like 1	2613	0.25
chr8_13491946_13492269	0.70	Gas6	growth arrest specific 6	2383	0.25
chr1_65186243_65186463	0.70	Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	85	0.79
chr19_31764456_31765203	0.70	Prkg1	protein kinase, cGMP-dependent, type I	144	0.98
chr10_14017752_14018957	0.70	Hivep2	human immunodeficiency virus type I enhancer binding protein 2	51330	0.13
chr12_91551959_91552341	0.69	Tshr	thyroid stimulating hormone receptor	14084	0.16
chr11_118744160_118745307	0.69	Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3	16308	0.21
chr3_96562001_96562194	0.69	Txnip	thioredoxin interacting protein	2043	0.13
chr10_20776929_20777274	0.68	Gm48651	predicted gene, 48651	20984	0.21
chr15_97765080_97766053	0.68	Rapgef3os2	Rap guanine nucleotide exchange factor (GEF) 3, opposite strand 2	983	0.36
chr8_34994050_34994306	0.68	Gm34368	predicted gene, 34368	14304	0.16
chr5_20583581_20583870	0.68	Gm3544	predicted gene 3544	4871	0.26
chr7_35948219_35949093	0.67	Gm28514	predicted gene 28514	110396	0.06
chr9_60742965_60743393	0.67	1700036A12Rik	RIKEN cDNA 1700036A12 gene	59	0.97
chr3_142390298_142390537	0.67	Pdlim5	PDZ and LIM domain 5	1391	0.52
chr11_110358024_110358368	0.67	Abca5	ATP-binding cassette, sub-family A (ABC1), member 5	20480	0.22
chr17_63865820_63865971	0.67	Fer	fer (fms/fps related) protein kinase	1880	0.34
chr1_62795476_62796303	0.67	Gm37121	predicted gene, 37121	13413	0.19
chr11_65266805_65267363	0.67	Myocd	myocardin	2770	0.29
chr7_61309034_61309202	0.67	A230006K03Rik	RIKEN cDNA A230006K03 gene	2595	0.4
chr11_70018020_70018411	0.67	Dlg4	discs large MAGUK scaffold protein 4	226	0.8
chr15_57659816_57660144	0.67	Zhx2	zinc fingers and homeoboxes 2	34685	0.17
chrX_166344270_166344507	0.66	Gpm6b	glycoprotein m6b	304	0.92
chr8_35592634_35593539	0.66	Gm16793	predicted gene, 16793	4114	0.21
chr16_59599420_59599980	0.65	Crybg3	beta-gamma crystallin domain containing 3	1279	0.47
chr13_110396048_110396669	0.65	Plk2	polo like kinase 2	346	0.91
chr19_45855235_45855499	0.65	Gm50196	predicted gene, 50196	11750	0.15
chr1_90204802_90205464	0.65	Ackr3	atypical chemokine receptor 3	1127	0.47
chr14_118080663_118081120	0.65	Dct	dopachrome tautomerase	28647	0.15
chr5_105052746_105052954	0.65	Gbp8	guanylate-binding protein 8	706	0.66
chr10_103015192_103015343	0.65	Alx1	ALX homeobox 1	7307	0.21
chr2_70315394_70315699	0.64	Rpl9-ps7	ribosomal protein L9, pseudogene 7	143436	0.04
chr11_31875409_31875592	0.64	Cpeb4	cytoplasmic polyadenylation element binding protein 4	2225	0.33
chr17_81480235_81480868	0.64	Gm11096	predicted gene 11096	38788	0.2
chr11_120186805_120187341	0.64	2810410L24Rik	RIKEN cDNA 2810410L24 gene	1678	0.23
chr2_57997628_57998772	0.63	Galnt5	polypeptide N-acetylgalactosaminyltransferase 5	316	0.9
chr17_10293681_10293832	0.63	Qk	quaking	10823	0.25
chr6_118194255_118194406	0.63	Ret	ret proto-oncogene	2803	0.25
chr9_95597786_95598558	0.62	Gm28164	predicted gene 28164	24247	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.6	1.9	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.6	2.4	GO:0003195	tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
0.6	1.7	GO:0048022	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.5	1.4	GO:0051684	maintenance of Golgi location(GO:0051684)
0.4	1.1	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.3	1.0	GO:0048769	sarcomerogenesis(GO:0048769)
0.3	0.6	GO:0035995	detection of muscle stretch(GO:0035995)
0.2	0.7	GO:1902608	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2	1.4	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2	0.8	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.2	0.4	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.2	1.0	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.2	0.6	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2	0.9	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.2	0.5	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.2	0.7	GO:1900378	regulation of melanin biosynthetic process(GO:0048021) positive regulation of melanin biosynthetic process(GO:0048023) regulation of secondary metabolite biosynthetic process(GO:1900376) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.2	0.5	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.2	0.5	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2	0.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	0.5	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.1	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	1.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.4	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1	0.4	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.1	0.7	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	1.7	GO:0030449	regulation of complement activation(GO:0030449)
0.1	0.4	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.4	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.4	GO:0042938	dipeptide transport(GO:0042938)
0.1	0.6	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.7	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1	0.7	GO:0006102	isocitrate metabolic process(GO:0006102)
0.1	0.3	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	1.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.3	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.1	0.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1	0.3	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
0.1	0.3	GO:0035907	dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.1	0.6	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.3	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	0.4	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.5	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.1	0.3	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1	0.8	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.4	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1	0.3	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	2.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.3	GO:0032345	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1	0.4	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1	0.2	GO:2000847	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1	0.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.3	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.1	0.3	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0060300	regulation of cytokine activity(GO:0060300)
0.1	0.1	GO:0089700	protein kinase D signaling(GO:0089700)
0.1	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1	0.3	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.2	GO:0035799	ureter maturation(GO:0035799)
0.1	0.3	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.1	0.3	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.1	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.2	GO:0061355	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.1	0.9	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.2	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1	0.2	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	0.2	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.1	0.2	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.1	0.2	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.1	0.2	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	1.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.2	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.1	0.3	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.3	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.1	0.2	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.1	0.1	GO:0035564	regulation of kidney size(GO:0035564)
0.1	0.3	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.2	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0060435	bronchiole development(GO:0060435)
0.0	0.2	GO:0044849	estrous cycle(GO:0044849)
0.0	0.1	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.2	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.0	0.2	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.5	GO:0030432	peristalsis(GO:0030432)
0.0	0.3	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0060921	sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0	0.1	GO:0033026	negative regulation of mast cell apoptotic process(GO:0033026)
0.0	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.1	GO:0060399	regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.6	GO:0001780	neutrophil homeostasis(GO:0001780)
0.0	0.2	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:0010912	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.0	GO:0072553	terminal button organization(GO:0072553)
0.0	0.2	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	1.1	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	0.2	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0003163	sinoatrial node development(GO:0003163)
0.0	0.2	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.3	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.2	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.1	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.1	GO:0002554	serotonin secretion by platelet(GO:0002554)
0.0	0.2	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.4	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0	0.1	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.4	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:1900200	mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.2	GO:0032026	response to magnesium ion(GO:0032026)
0.0	0.0	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.3	GO:0032060	bleb assembly(GO:0032060)
0.0	0.6	GO:0097352	autophagosome maturation(GO:0097352)
0.0	0.1	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.0	0.2	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.2	GO:0035811	negative regulation of urine volume(GO:0035811)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.0	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0061642	chemoattraction of axon(GO:0061642)
0.0	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.3	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.2	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.0	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.0	GO:0072298	regulation of metanephric glomerulus development(GO:0072298)
0.0	0.2	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:1903818	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	1.4	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.0	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.0	0.1	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.2	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.0	GO:0043379	memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.3	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.2	GO:0097369	sodium ion import(GO:0097369)
0.0	0.2	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0045226	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0	0.1	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.2	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.3	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.1	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.1	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.1	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.6	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	0.2	GO:0060347	heart trabecula formation(GO:0060347)
0.0	1.1	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0060618	nipple development(GO:0060618)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.3	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.2	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.1	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.1	GO:0060279	positive regulation of ovulation(GO:0060279)
0.0	0.4	GO:0048305	immunoglobulin secretion(GO:0048305)
0.0	0.2	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.0	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0	0.1	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.0	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0019054	modulation by virus of host process(GO:0019054)
0.0	0.0	GO:0046016	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0	0.6	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.2	GO:0007614	short-term memory(GO:0007614)
0.0	0.0	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.1	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
0.0	0.1	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.0	GO:0036295	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.4	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	0.0	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.2	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.3	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.1	GO:0071295	cellular response to vitamin(GO:0071295)
0.0	0.1	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.0	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0	0.2	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0	0.0	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.0	GO:1901859	regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.1	GO:0002934	desmosome organization(GO:0002934)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0071435	potassium ion export(GO:0071435)
0.0	0.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.2	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.0	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.0	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.0	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.0	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.0	GO:1901723	negative regulation of cell proliferation involved in kidney development(GO:1901723)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.0	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.1	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.2	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.3	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0021756	striatum development(GO:0021756)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.0	0.1	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	0.1	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.0	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0	0.0	GO:0006868	glutamine transport(GO:0006868)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.0	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.0	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.0	GO:0042504	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0010543	regulation of platelet activation(GO:0010543)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.2	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.1	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.2	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.0	GO:0045794	negative regulation of cell volume(GO:0045794)
0.0	0.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.0	GO:0051187	cofactor catabolic process(GO:0051187)
0.0	0.0	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.0	0.1	GO:0072102	glomerulus morphogenesis(GO:0072102)
0.0	0.2	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.0	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.0	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.0	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.0	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.0	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0	0.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.0	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0071732	cellular response to nitric oxide(GO:0071732)
0.0	0.0	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.0	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.0	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.0	0.1	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.0	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.2	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.3	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.1	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.0	1.2	GO:0035304	regulation of protein dephosphorylation(GO:0035304)
0.0	0.0	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.0	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.0	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.0	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.1	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.0	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.5	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.5	1.4	GO:0043259	laminin-10 complex(GO:0043259)
0.3	1.0	GO:0097443	sorting endosome(GO:0097443)
0.1	1.1	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.1	0.8	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	0.3	GO:0046691	intracellular canaliculus(GO:0046691)
0.1	0.4	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.5	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	0.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1	0.6	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.5	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.4	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1	1.1	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.1	0.2	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.5	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.6	GO:0005916	fascia adherens(GO:0005916)
0.0	0.8	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.1	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0097255	R2TP complex(GO:0097255)
0.0	0.3	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.3	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	1.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.3	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.2	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	2.7	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.3	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.2	GO:0097422	tubular endosome(GO:0097422)
0.0	0.5	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.3	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	1.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.6	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.3	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.0	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.2	GO:0000124	SAGA complex(GO:0000124)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	1.9	GO:0030139	endocytic vesicle(GO:0030139)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.0	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.1	GO:0090543	Flemming body(GO:0090543)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0043511	inhibin complex(GO:0043511)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.1	GO:0031674	I band(GO:0031674)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.2	GO:0005605	basal lamina(GO:0005605)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.0	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.8	GO:0042383	sarcolemma(GO:0042383)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.0	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.0	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.0	GO:0016607	nuclear speck(GO:0016607)
0.0	0.0	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.2	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.4	GO:0016459	myosin complex(GO:0016459)
0.0	0.5	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.0	GO:0005745	m-AAA complex(GO:0005745)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.3	1.0	GO:0035939	microsatellite binding(GO:0035939)
0.3	1.3	GO:0031433	telethonin binding(GO:0031433)
0.3	1.9	GO:0003680	AT DNA binding(GO:0003680)
0.2	1.4	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2	1.4	GO:0043208	glycosphingolipid binding(GO:0043208)
0.2	0.2	GO:0003696	satellite DNA binding(GO:0003696)
0.2	1.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	0.7	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	0.4	GO:0042895	antibiotic transporter activity(GO:0042895)
0.1	1.6	GO:0001846	opsonin binding(GO:0001846)
0.1	0.8	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.5	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.1	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.3	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	0.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.6	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.4	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.5	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.2	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.1	GO:0030519	snoRNP binding(GO:0030519)
0.1	0.3	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.9	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	0.4	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.8	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	0.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.3	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.3	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.2	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.2	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.2	GO:0004359	glutaminase activity(GO:0004359)
0.1	0.2	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	0.6	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.2	GO:0015368	calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.1	0.2	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	0.3	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.1	0.2	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.7	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.3	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	2.5	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.2	GO:0043955	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.2	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.4	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	4.9	GO:0044325	ion channel binding(GO:0044325)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.8	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.7	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.8	GO:0042805	actinin binding(GO:0042805)
0.0	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0036122	BMP binding(GO:0036122)
0.0	0.2	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.4	GO:0031005	filamin binding(GO:0031005)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.3	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.3	GO:0034821	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.1	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.3	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	1.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.2	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.0	2.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.0	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.3	GO:0044688	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.0	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0022821	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.4	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.1	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.0	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	1.3	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.8	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	3.5	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0016937	short-branched-chain-acyl-CoA dehydrogenase activity(GO:0016937)
0.0	0.0	GO:0030984	kininogen binding(GO:0030984)
0.0	0.0	GO:0034786	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	1.2	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.0	GO:0050733	RS domain binding(GO:0050733)
0.0	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.0	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0	0.3	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.2	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0044466	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.0	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.0	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.4	GO:0050661	NADP binding(GO:0050661)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.0	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.2	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	1.0	GO:0004222	metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	2.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	0.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	1.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.5	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.9	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.9	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.5	PID MYC PATHWAY	C-MYC pathway
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.5	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.3	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.2	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.3	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	1.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	0.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.6	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.8	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.5	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	2.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	1.0	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	1.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation