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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Myod1

Z-value: 0.52

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Transcription factors associated with Myod1

Gene Symbol	Gene ID	Gene Info
Myod1 Ensembl NCBI MGI UniProt	ENSMUSG00000009471.3	Myod1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Myod1	chr7_46376321_46379126	1249	0.401431	0.28	2.9e-02	Click!
Myod1	chr7_46375692_46376219	519	0.741117	0.18	1.6e-01	Click!
Myod1	chr7_46375296_46375447	1103	0.446948	0.08	5.5e-01	Click!

Activity of the Myod1 motif across conditions

Conditions sorted by the z-value of the Myod1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_162217585_162219370	0.94	Dnm3os	dynamin 3, opposite strand	601	0.46
chr16_38363598_38364152	0.42	Popdc2	popeye domain containing 2	1630	0.26
chr9_115096411_115096891	0.42	Osbpl10	oxysterol binding protein-like 10	7810	0.23
chr8_57326741_57329467	0.40	Hand2os1	Hand2, opposite strand 1	3871	0.15
chr4_11385045_11386187	0.38	Esrp1	epithelial splicing regulatory protein 1	778	0.6
chr13_55835316_55837389	0.37	Pitx1	paired-like homeodomain transcription factor 1	160	0.62
chr18_65348348_65348930	0.37	Gm41757	predicted gene, 41757	518	0.56
chr3_128990459_128991248	0.35	Gm9387	predicted pseudogene 9387	35755	0.19
chr12_73039135_73040425	0.33	Six1	sine oculis-related homeobox 1	3035	0.27
chr9_20972154_20973375	0.33	S1pr2	sphingosine-1-phosphate receptor 2	1214	0.26
chr13_63273798_63275383	0.32	Gm47585	predicted gene, 47585	990	0.28
chr12_112747021_112747471	0.32	Cep170b	centrosomal protein 170B	3282	0.12
chr18_65083730_65084940	0.31	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	1281	0.54
chr8_87938260_87939386	0.31	Zfp423	zinc finger protein 423	5229	0.29
chr1_135324343_135325907	0.31	Lmod1	leiomodin 1 (smooth muscle)	318	0.83
chr9_87729583_87731038	0.31	Tbx18	T-box18	187	0.9
chr17_68002299_68002969	0.31	Arhgap28	Rho GTPase activating protein 28	1486	0.54
chr7_44474127_44475010	0.31	5430431A17Rik	RIKEN cDNA 5430431A17 gene	1030	0.25
chr12_9573836_9576858	0.30	Osr1	odd-skipped related transcription factor 1	906	0.56
chr2_180389757_180390438	0.29	Mir1a-1	microRNA 1a-1	1049	0.41
chr16_44015370_44016774	0.29	Gramd1c	GRAM domain containing 1C	364	0.83
chr10_39614434_39615372	0.29	Gm16364	predicted gene 16364	1221	0.36
chr9_120021835_120022273	0.29	Xirp1	xin actin-binding repeat containing 1	1544	0.23
chr12_4523121_4523682	0.29	Gm31938	predicted gene, 31938	712	0.6
chr9_21851806_21852608	0.28	Dock6	dedicator of cytokinesis 6	409	0.74
chr11_47377104_47378325	0.27	Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	1808	0.52
chr11_85885788_85887022	0.27	Tbx4	T-box 4	17	0.97
chr11_100144835_100146198	0.27	Krt19	keratin 19	604	0.52
chr1_106629982_106630261	0.27	Gm37053	predicted gene, 37053	23251	0.19
chr5_113798574_113798890	0.27	Tmem119	transmembrane protein 119	1714	0.21
chr1_14303973_14305599	0.26	Eya1	EYA transcriptional coactivator and phosphatase 1	158	0.97
chr7_6727103_6728704	0.26	Peg3	paternally expressed 3	2516	0.14
chr2_35623294_35623923	0.26	Dab2ip	disabled 2 interacting protein	1448	0.46
chr8_107545084_107547731	0.26	Wwp2	WW domain containing E3 ubiquitin protein ligase 2	1395	0.4
chr16_21207155_21207444	0.26	Ephb3	Eph receptor B3	2544	0.25
chr6_24599678_24600100	0.25	Lmod2	leiomodin 2 (cardiac)	2127	0.25
chr4_43520861_43521689	0.25	Tpm2	tropomyosin 2, beta	1606	0.17
chr14_101886064_101886474	0.25	Lmo7	LIM domain only 7	2150	0.43
chr11_69714656_69715350	0.25	Gm12307	predicted gene 12307	15581	0.05
chr8_121118797_121121438	0.24	Foxc2	forkhead box C2	3946	0.14
chr17_42741899_42742151	0.24	Adgrf2	adhesion G protein-coupled receptor F2	154	0.96
chr17_44301052_44301539	0.24	Clic5	chloride intracellular channel 5	64189	0.12
chr9_92276388_92276986	0.23	Plscr2	phospholipid scramblase 2	941	0.48
chr3_105815846_105816287	0.23	Gm5547	predicted gene 5547	499	0.69
chr7_114103782_114104353	0.23	Rras2	related RAS viral (r-ras) oncogene 2	13697	0.21
chr3_146117173_146118635	0.23	Mcoln3	mucolipin 3	454	0.73
chr9_66512511_66514532	0.23	Fbxl22	F-box and leucine-rich repeat protein 22	1088	0.47
chr13_55825087_55826711	0.23	Gm47071	predicted gene, 47071	351	0.82
chr17_24752448_24753648	0.23	Hs3st6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	32	0.93
chr4_43399011_43400247	0.23	Rusc2	RUN and SH3 domain containing 2	1609	0.28
chr15_101293230_101294713	0.23	Smim41	small integral membrane protein 41	739	0.47
chr11_114216624_114216941	0.22	1700092K14Rik	RIKEN cDNA 1700092K14 gene	18524	0.15
chr1_75360071_75361415	0.22	Des	desmin	414	0.72
chr14_34585878_34586349	0.22	Ldb3	LIM domain binding 3	2368	0.19
chr2_163694015_163694536	0.22	Pkig	protein kinase inhibitor, gamma	237	0.89
chr11_115974294_115975742	0.22	Itgb4	integrin beta 4	39	0.95
chr4_114907257_114907947	0.22	Foxd2	forkhead box D2	1271	0.3
chr6_51193157_51193734	0.22	Mir148a	microRNA 148a	76465	0.1
chr13_72629730_72632045	0.22	Irx2	Iroquois homeobox 2	1062	0.51
chr8_41015082_41015919	0.21	Mtus1	mitochondrial tumor suppressor 1	820	0.53
chr17_88791510_88792237	0.21	Lhcgr	luteinizing hormone/choriogonadotropin receptor	98	0.98
chr9_74110075_74111065	0.21	Wdr72	WD repeat domain 72	166	0.97
chr19_55746711_55749175	0.21	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	5098	0.32
chr9_56712934_56713139	0.21	Lingo1	leucine rich repeat and Ig domain containing 1	27783	0.18
chr3_87951379_87952516	0.21	Crabp2	cellular retinoic acid binding protein II	197	0.87
chr4_141302731_141302975	0.21	Epha2	Eph receptor A2	446	0.71
chr8_111745500_111746511	0.21	Bcar1	breast cancer anti-estrogen resistance 1	2196	0.3
chr4_134237503_134238650	0.20	Cnksr1	connector enhancer of kinase suppressor of Ras 1	263	0.8
chr7_140899782_140900558	0.20	Cox8b	cytochrome c oxidase subunit 8B	276	0.74
chr18_29242584_29242819	0.20	Gm34743	predicted gene, 34743	2646	0.43
chr11_8622429_8622770	0.20	Tns3	tensin 3	2288	0.45
chr2_173057598_173057795	0.20	Gm14453	predicted gene 14453	23116	0.12
chr5_137610176_137611504	0.20	Pcolce	procollagen C-endopeptidase enhancer protein	138	0.86
chr5_30913519_30915234	0.20	Emilin1	elastin microfibril interfacer 1	637	0.48
chr13_31625167_31627270	0.20	Gm27516	predicted gene, 27516	325	0.4
chr11_102623866_102624954	0.20	2810433D01Rik	RIKEN cDNA 2810433D01 gene	6	0.95
chr9_44136029_44136582	0.20	Mcam	melanoma cell adhesion molecule	239	0.78
chr18_76542618_76543294	0.20	Gm31933	predicted gene, 31933	89914	0.09
chr2_70083482_70084035	0.20	Myo3b	myosin IIIB	684	0.74
chr16_26041199_26042258	0.20	AU015336	expressed sequence AU015336	460	0.86
chr13_102903771_102904870	0.20	Mast4	microtubule associated serine/threonine kinase family member 4	1466	0.56
chr4_124276838_124278353	0.20	Gm37667	predicted gene, 37667	1582	0.35
chr2_69673818_69673969	0.19	Klhl41	kelch-like 41	3773	0.18
chr3_138069501_138070764	0.19	1110002E22Rik	RIKEN cDNA 1110002E22 gene	1465	0.3
chr7_17061715_17062460	0.19	Hif3a	hypoxia inducible factor 3, alpha subunit	297	0.82
chr9_45203520_45204009	0.19	Tmprss4	transmembrane protease, serine 4	222	0.87
chr2_84423814_84425562	0.19	Calcrl	calcitonin receptor-like	578	0.75
chr7_18957439_18958650	0.19	Nanos2	nanos C2HC-type zinc finger 2	29356	0.06
chr1_74035856_74036007	0.19	Tns1	tensin 1	1202	0.53
chr19_25411022_25411281	0.19	Kank1	KN motif and ankyrin repeat domains 1	4452	0.24
chr10_79988072_79989720	0.19	Cnn2	calponin 2	273	0.76
chr19_24861287_24862270	0.19	Pgm5	phosphoglucomutase 5	77	0.96
chr1_51291546_51292409	0.19	Cavin2	caveolae associated 2	2851	0.27
chr12_33966605_33968831	0.19	Twist1	twist basic helix-loop-helix transcription factor 1	10047	0.22
chr11_96334278_96335532	0.19	Hoxb3	homeobox B3	6040	0.08
chr4_124701261_124701890	0.19	Fhl3	four and a half LIM domains 3	855	0.37
chr8_80119316_80119579	0.19	Gm5909	predicted gene 5909	7361	0.19
chr2_28138697_28138848	0.18	F730016J06Rik	RIKEN cDNA F730016J06 gene	20565	0.17
chr14_67271890_67272768	0.18	Gm23178	predicted gene, 23178	2634	0.24
chr9_24874511_24875131	0.18	Amd-ps6	S-adenosylmethionine decarboxylase, pseudogene 6	47476	0.12
chr2_35627849_35628114	0.18	Dab2ip	disabled 2 interacting protein	5821	0.24
chr7_112228733_112229227	0.18	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	3090	0.35
chr1_40874622_40874941	0.18	Gm5973	predicted gene 5973	10549	0.23
chr15_89425017_89425997	0.18	Cpt1b	carnitine palmitoyltransferase 1b, muscle	288	0.74
chr13_92425754_92427030	0.18	Ankrd34b	ankyrin repeat domain 34B	51	0.94
chr1_88639699_88640131	0.18	Gm38130	predicted gene, 38130	13170	0.17
chr4_148960341_148961414	0.18	Gm17029	predicted gene 17029	517	0.74
chr9_21311433_21311747	0.18	Ap1m2	adaptor protein complex AP-1, mu 2 subunit	721	0.46
chr7_70280148_70281631	0.18	Gm29327	predicted gene 29327	31113	0.13
chr3_133233594_133234317	0.18	Arhgef38	Rho guanine nucleotide exchange factor (GEF) 38	934	0.64
chr3_68585286_68585461	0.18	Schip1	schwannomin interacting protein 1	1194	0.53
chr9_59947366_59947592	0.18	Nr2e3	nuclear receptor subfamily 2, group E, member 3	1312	0.32
chr11_113611912_113612498	0.18	Sstr2	somatostatin receptor 2	7137	0.18
chr3_8736196_8736672	0.18	C230057A21Rik	RIKEN cDNA C230057A21 gene	74	0.97
chr6_145942273_145942684	0.18	Gm43931	predicted gene, 43931	4598	0.18
chr8_71684084_71684803	0.18	Insl3	insulin-like 3	4771	0.09
chr18_60963369_60963520	0.18	Camk2a	calcium/calmodulin-dependent protein kinase II alpha	110	0.95
chr3_30104992_30105810	0.17	Mecom	MDS1 and EVI1 complex locus	35022	0.17
chr6_14903005_14903973	0.17	Foxp2	forkhead box P2	32	0.99
chr14_63236760_63237176	0.17	Gata4	GATA binding protein 4	8280	0.17
chr9_71770829_71771315	0.17	Cgnl1	cingulin-like 1	488	0.81
chr3_135285527_135285798	0.17	Bdh2	3-hydroxybutyrate dehydrogenase, type 2	2996	0.21
chr17_62655730_62656448	0.17	Gm25800	predicted gene, 25800	198969	0.03
chr2_93177441_93177592	0.17	Trp53i11	transformation related protein 53 inducible protein 11	10032	0.22
chr7_49522042_49523415	0.17	Nav2	neuron navigator 2	25464	0.21
chr6_120275123_120275344	0.17	B4galnt3	beta-1,4-N-acetyl-galactosaminyl transferase 3	19326	0.19
chr5_119842721_119843952	0.17	Tbx5	T-box 5	7181	0.18
chr1_18961494_18962019	0.17	Gm24075	predicted gene, 24075	8077	0.26
chr16_87553258_87554074	0.17	Map3k7cl	Map3k7 C-terminal like	336	0.84
chr7_121735353_121735504	0.17	Scnn1g	sodium channel, nonvoltage-gated 1 gamma	949	0.56
chr16_38360437_38360588	0.17	Popdc2	popeye domain containing 2	1697	0.25
chr3_19622651_19622802	0.17	1700064H15Rik	RIKEN cDNA 1700064H15 gene	5951	0.17
chr16_78326082_78326665	0.17	Cxadr	coxsackie virus and adenovirus receptor	1166	0.43
chr16_42152536_42153083	0.17	Lsamp	limbic system-associated membrane protein	8784	0.22
chr8_18740237_18741640	0.17	Angpt2	angiopoietin 2	624	0.75
chr10_75174015_75174616	0.17	Bcr	BCR activator of RhoGEF and GTPase	350	0.89
chr11_55414788_55415644	0.17	Sparc	secreted acidic cysteine rich glycoprotein	4682	0.18
chr6_54272742_54273928	0.17	Chn2	chimerin 2	427	0.82
chr2_30850400_30850833	0.17	Prrx2	paired related homeobox 2	5172	0.14
chr1_75362633_75362784	0.17	Des	desmin	678	0.52
chr7_141117549_141118467	0.17	Ano9	anoctamin 9	202	0.85
chr3_69548831_69549124	0.17	Ppm1l	protein phosphatase 1 (formerly 2C)-like	2	0.98
chr5_113136296_113136937	0.17	2900026A02Rik	RIKEN cDNA 2900026A02 gene	1370	0.27
chr11_106365272_106365607	0.17	Prr29	proline rich 29	33	0.96
chr16_18696451_18696829	0.16	Rps2-ps7	ribosomal protein S2, pseudogene 7	14424	0.15
chr1_189924428_189924893	0.16	Smyd2	SET and MYND domain containing 2	2297	0.28
chr5_81519288_81520108	0.16	Gm43084	predicted gene 43084	16028	0.29
chr17_12744783_12745031	0.16	Airn	antisense Igf2r RNA	3509	0.17
chr15_73707761_73707912	0.16	Gpr20	G protein-coupled receptor 20	331	0.86
chr4_57295053_57295204	0.16	Gm12536	predicted gene 12536	4968	0.2
chr9_40325276_40326082	0.16	1700110K17Rik	RIKEN cDNA 1700110K17 gene	2253	0.19
chr8_26272856_26273881	0.16	Gm31727	predicted gene, 31727	6391	0.14
chr1_93190721_93191081	0.16	Crocc2	ciliary rootlet coiled-coil, rootletin family member 2	22176	0.11
chr8_113433901_113434458	0.16	Gm25766	predicted gene, 25766	85427	0.09
chr13_23497689_23499269	0.16	Btn2a2	butyrophilin, subfamily 2, member A2	9622	0.06
chr6_139586816_139587911	0.16	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	126	0.96
chr7_100926314_100930096	0.16	Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17	3902	0.17
chr2_84634714_84636973	0.16	Ctnnd1	catenin (cadherin associated protein), delta 1	2262	0.17
chr3_131110318_131112630	0.16	Lef1os1	LEF1 opposite strand RNA 1	616	0.56
chr9_107550029_107550198	0.16	Zmynd10	zinc finger, MYND domain containing 10	376	0.48
chr15_96135146_96135802	0.16	D030018L15Rik	RIKEN cDNA D030018L15 gene	55921	0.13
chr13_46428917_46429384	0.16	Rbm24	RNA binding motif protein 24	7328	0.24
chr12_38778127_38778471	0.16	Etv1	ets variant 1	1081	0.56
chr3_55779960_55781204	0.16	Mab21l1	mab-21-like 1	1928	0.32
chr3_57576670_57576821	0.16	Wwtr1	WW domain containing transcription regulator 1	835	0.56
chr18_66344941_66345611	0.16	Ccbe1	collagen and calcium binding EGF domains 1	42535	0.1
chr13_60455009_60455742	0.16	Gm35333	predicted gene, 35333	20644	0.15
chr1_189775009_189775805	0.16	Ptpn14	protein tyrosine phosphatase, non-receptor type 14	11229	0.19
chr7_19461513_19461793	0.16	Gm23099	predicted gene, 23099	718	0.38
chr1_58713328_58714310	0.16	Cflar	CASP8 and FADD-like apoptosis regulator	67	0.96
chr8_121086245_121087227	0.16	Gm27530	predicted gene, 27530	2030	0.19
chr3_51778939_51779197	0.16	Gm37342	predicted gene, 37342	16980	0.11
chr4_148780321_148780472	0.16	Casz1	castor zinc finger 1	24033	0.18
chr15_101139270_101139421	0.16	Acvrl1	activin A receptor, type II-like 1	1745	0.23
chr12_23188694_23189971	0.16	Gm47385	predicted gene, 47385	66	0.96
chr7_28070851_28071079	0.15	Fcgbp	Fc fragment of IgG binding protein	271	0.86
chr2_13577101_13577578	0.15	Vim	vimentin	2030	0.37
chr8_25343082_25343881	0.15	5430421F17Rik	RIKEN cDNA 5430421F17 gene	37211	0.12
chr5_38549575_38549794	0.15	Gm22249	predicted gene, 22249	3226	0.2
chr10_79639823_79639974	0.15	Shc2	SHC (Src homology 2 domain containing) transforming protein 2	1980	0.14
chr12_26068051_26068784	0.15	Gm47750	predicted gene, 47750	81899	0.09
chr10_94520068_94521446	0.15	Tmcc3	transmembrane and coiled coil domains 3	5900	0.23
chr2_13579434_13579672	0.15	Vim	vimentin	184	0.96
chr10_88336673_88337098	0.15	Dram1	DNA-damage regulated autophagy modulator 1	20111	0.14
chr5_127227734_127228696	0.15	Tmem132c	transmembrane protein 132C	13593	0.18
chr5_123059978_123060693	0.15	Gm6444	predicted gene 6444	5907	0.09
chr9_14675747_14675965	0.15	Gm19790	predicted gene, 19790	4114	0.11
chr6_89345563_89345754	0.15	Gm44207	predicted gene, 44207	518	0.74
chr2_132944858_132946039	0.15	Fermt1	fermitin family member 1	181	0.93
chr19_28504036_28504436	0.15	Glis3	GLIS family zinc finger 3	36184	0.2
chr16_85797660_85797940	0.15	Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	1838	0.41
chr16_32486028_32486482	0.15	Slc51a	solute carrier family 51, alpha subunit	1448	0.3
chr6_56617179_56617515	0.15	Gm22493	predicted gene, 22493	16398	0.17
chr5_111221096_111221247	0.15	Ttc28	tetratricopeptide repeat domain 28	4287	0.22
chr9_44085798_44086457	0.15	Usp2	ubiquitin specific peptidase 2	1063	0.25
chr17_34497017_34497248	0.15	Btnl5-ps	butyrophilin-like 5, pseudogene	297	0.75
chr18_50087652_50087803	0.15	C030005K06Rik	RIKEN cDNA C030005K06 gene	33883	0.13
chr18_35739288_35740804	0.15	Sting1	stimulator of interferon response cGAMP interactor 1	30	0.95
chr5_113335226_113336256	0.15	Mir7230	microRNA 7230	1904	0.22
chr10_24958395_24959363	0.15	Gm36172	predicted gene, 36172	31260	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Myod1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	0.2	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.1	0.2	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	0.3	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.2	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.1	0.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.2	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1	0.2	GO:0060931	sinoatrial node cell development(GO:0060931)
0.1	0.3	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.2	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1	0.2	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.1	0.2	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.3	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.2	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.3	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0	0.1	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.0	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.2	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.4	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.2	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.1	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.1	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0	0.1	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.2	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.1	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.2	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.2	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.0	GO:0072095	regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.0	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.0	0.3	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0	0.1	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.0	0.2	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.0	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.1	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.0	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.0	0.1	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0061074	regulation of neural retina development(GO:0061074)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.0	GO:0072179	nephric duct formation(GO:0072179)
0.0	0.1	GO:0060066	oviduct development(GO:0060066)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.0	GO:1902338	negative regulation of apoptotic process involved in morphogenesis(GO:1902338)
0.0	0.1	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.0	GO:1900135	positive regulation of renin secretion into blood stream(GO:1900135)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.2	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
0.0	0.0	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.3	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.0	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.0	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.0	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.0	0.0	GO:1901166	neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0	0.0	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.2	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.0	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.0	0.3	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.0	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.0	0.0	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.2	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.0	GO:0060486	Clara cell differentiation(GO:0060486)
0.0	0.0	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.0	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.1	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.0	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.1	GO:0099624	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0	0.0	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.1	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0090032	negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0	0.1	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.1	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.0	GO:0010912	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.0	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.0	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:0090220	chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0	0.0	GO:0032439	endosome localization(GO:0032439)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.2	GO:0005914	spot adherens junction(GO:0005914)
0.1	0.2	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.1	0.3	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:1990357	terminal web(GO:1990357)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.5	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.5	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.2	GO:1990254	keratin filament binding(GO:1990254)
0.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	GO:0070840	dynein complex binding(GO:0070840)
0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	GO:0038132	neuregulin binding(GO:0038132)
0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.2	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1	GO:0030274	LIM domain binding(GO:0030274)
0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	GO:0034711	inhibin binding(GO:0034711)
0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.2	GO:0016918	retinal binding(GO:0016918)
0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	GO:0039706	co-receptor binding(GO:0039706)
0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.2	GO:0043274	phospholipase binding(GO:0043274)
0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	GO:0018641	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.7	PID AURORA B PATHWAY	Aurora B signaling
0.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII