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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Nfat5

Z-value: 0.79

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Transcription factors associated with Nfat5

Gene Symbol	Gene ID	Gene Info
Nfat5 Ensembl NCBI MGI UniProt	ENSMUSG00000003847.10	nuclear factor of activated T cells 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_107336573_107336890	Nfat5	1777	0.363267	0.30	1.8e-02	Click!
chr8_107297033_107297184	Nfat5	3549	0.242841	0.26	4.1e-02	Click!
chr8_107344888_107345039	Nfat5	177	0.951000	-0.24	6.1e-02	Click!
chr8_107295537_107295867	Nfat5	2143	0.317928	0.23	7.9e-02	Click!
chr8_107292893_107293194	Nfat5	427	0.843177	0.10	4.3e-01	Click!

Activity of the Nfat5 motif across conditions

Conditions sorted by the z-value of the Nfat5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_139586816_139587911	1.58	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	126	0.96
chr3_19647545_19647696	1.53	Trim55	tripartite motif-containing 55	3112	0.2
chr1_164455819_164456603	1.45	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	1811	0.27
chr17_81734587_81734955	1.41	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	3606	0.34
chr17_72921491_72924008	1.37	Lbh	limb-bud and heart	1561	0.47
chr2_35691764_35692937	1.35	Dab2ip	disabled 2 interacting protein	17	0.98
chr14_59478693_59479244	1.33	Cab39l	calcium binding protein 39-like	152	0.96
chr1_130732649_130733832	1.24	AA986860	expressed sequence AA986860	1130	0.29
chr14_31166307_31168596	1.18	Stab1	stabilin 1	1144	0.34
chr18_4350648_4350799	1.14	Map3k8	mitogen-activated protein kinase kinase kinase 8	2234	0.19
chr18_12256920_12257106	1.14	Ankrd29	ankyrin repeat domain 29	14684	0.14
chrX_74248072_74248576	1.13	Flna	filamin, alpha	1496	0.18
chr8_28593556_28594184	1.10	Gm26795	predicted gene, 26795	338	0.92
chr13_106835269_106836682	1.10	Lrrc70	leucine rich repeat containing 70	173	0.7
chr16_74900702_74901266	1.08	Gm49674	predicted gene, 49674	25046	0.23
chr10_18447141_18447345	1.02	Nhsl1	NHS-like 1	22645	0.22
chr17_43389439_43390317	1.00	Adgrf5	adhesion G protein-coupled receptor F5	390	0.89
chr6_115982816_115983479	0.99	Plxnd1	plexin D1	11858	0.14
chr2_148856545_148856768	0.99	Cstdc2	cystatin domain containing 2	5722	0.13
chr1_164454554_164455430	0.94	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	1215	0.39
chr5_32140229_32140654	0.93	Fosl2	fos-like antigen 2	4268	0.18
chr5_39716146_39716373	0.92	Hs3st1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	39216	0.18
chr3_153783659_153783895	0.91	Gm10042	predicted gene 10042	1276	0.34
chr7_112217172_112217348	0.91	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	8596	0.27
chr7_130576739_130577783	0.89	Tacc2	transforming, acidic coiled-coil containing protein 2	177	0.94
chr16_50752363_50752789	0.89	Dubr	Dppa2 upstream binding RNA	19803	0.17
chr11_83849571_83850989	0.89	Hnf1b	HNF1 homeobox B	217	0.83
chr8_78771411_78771855	0.87	Gm47209	predicted gene, 47209	2912	0.24
chr6_17309182_17310034	0.87	Cav1	caveolin 1, caveolae protein	1885	0.33
chr6_119052982_119053231	0.86	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	26901	0.24
chr5_29477932_29478829	0.86	Mnx1	motor neuron and pancreas homeobox 1	90	0.96
chr18_76200378_76201192	0.86	Gm9028	predicted gene 9028	23398	0.15
chrX_82949777_82950054	0.85	Dmd	dystrophin, muscular dystrophy	1012	0.71
chr15_8967409_8968940	0.84	Ranbp3l	RAN binding protein 3-like	172	0.96
chr7_75655315_75655603	0.83	Akap13	A kinase (PRKA) anchor protein 13	11274	0.18
chr17_81736193_81736564	0.82	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	1999	0.44
chr9_105520039_105521535	0.82	Atp2c1	ATPase, Ca++-sequestering	360	0.86
chr14_63247276_63249044	0.81	Gata4	GATA binding protein 4	2889	0.24
chr19_27364312_27364550	0.81	Gm50113	predicted gene, 50113	1641	0.36
chr8_127499907_127500504	0.81	Pard3	par-3 family cell polarity regulator	52459	0.15
chr3_79885722_79887545	0.80	Gm36569	predicted gene, 36569	173	0.83
chr18_45269269_45269613	0.80	Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	436	0.85
chr14_20663037_20663711	0.80	Synpo2l	synaptopodin 2-like	1200	0.26
chr14_120296391_120298017	0.79	Mbnl2	muscleblind like splicing factor 2	470	0.87
chr14_54959527_54959749	0.78	Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	1731	0.13
chr1_144055657_144055889	0.78	Rgs2	regulator of G-protein signaling 2	51612	0.16
chr5_116419135_116419697	0.78	Hspb8	heat shock protein 8	3448	0.16
chr6_57533615_57533966	0.78	Ppm1k	protein phosphatase 1K (PP2C domain containing)	1636	0.32
chr6_124919073_124920498	0.77	Ptms	parathymosin	318	0.73
chr11_107335368_107335799	0.77	Pitpnc1	phosphatidylinositol transfer protein, cytoplasmic 1	1943	0.23
chr8_69887012_69889642	0.76	Yjefn3	YjeF N-terminal domain containing 3	142	0.84
chr1_138608112_138608354	0.76	Nek7	NIMA (never in mitosis gene a)-related expressed kinase 7	11441	0.18
chr3_66292264_66292972	0.76	Veph1	ventricular zone expressed PH domain-containing 1	4130	0.27
chr16_97606744_97607108	0.75	Tmprss2	transmembrane protease, serine 2	4043	0.25
chr19_57275523_57275688	0.74	4930449E18Rik	RIKEN cDNA 4930449E18 gene	1645	0.38
chr5_141414827_141414978	0.74	Gm16035	predicted gene 16035	33976	0.16
chr6_37431738_37432032	0.74	Creb3l2	cAMP responsive element binding protein 3-like 2	10261	0.27
chr13_97390464_97390915	0.74	Gm33447	predicted gene, 33447	14455	0.18
chr8_80811787_80812072	0.73	Gab1	growth factor receptor bound protein 2-associated protein 1	18955	0.18
chr8_111923307_111923610	0.73	Tmem231	transmembrane protein 231	4702	0.15
chr5_143558813_143558964	0.73	Fam220a	family with sequence similarity 220, member A	9848	0.14
chr1_23271255_23272383	0.72	Mir30a	microRNA 30a	450	0.73
chr3_151749374_151749990	0.72	Ifi44	interferon-induced protein 44	200	0.95
chr12_73587091_73587345	0.72	Prkch	protein kinase C, eta	2375	0.29
chr9_56866808_56868850	0.71	Cspg4	chondroitin sulfate proteoglycan 4	2796	0.18
chr7_126624812_126625701	0.69	Nupr1	nuclear protein transcription regulator 1	88	0.92
chr3_153689877_153690164	0.69	Gm22206	predicted gene, 22206	18891	0.16
chr7_137526118_137526299	0.69	Gm45397	predicted gene 45397	38380	0.18
chr1_188003839_188004226	0.69	9330162B11Rik	RIKEN cDNA 9330162B11 gene	4958	0.26
chr15_68937001_68937382	0.69	Khdrbs3	KH domain containing, RNA binding, signal transduction associated 3	7123	0.23
chr16_93938522_93938959	0.67	Cldn14	claudin 14	3644	0.18
chr1_23261578_23261729	0.67	Gm6420	predicted gene 6420	5246	0.13
chr16_23611686_23611850	0.67	Rtp4	receptor transporter protein 4	1843	0.39
chrX_71964243_71964394	0.67	Prrg3	proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)	1336	0.41
chr5_119841347_119842608	0.67	Tbx5	T-box 5	5822	0.19
chr13_89541543_89541900	0.66	Hapln1	hyaluronan and proteoglycan link protein 1	1925	0.42
chr11_96254039_96254881	0.66	Gm53	predicted gene 53	1928	0.15
chr13_108497868_108498217	0.66	Pde4d	phosphodiesterase 4D, cAMP specific	48033	0.17
chr6_134151167_134151791	0.66	Gm17088	predicted gene 17088	20528	0.18
chr17_50678196_50678377	0.66	Gm7334	predicted gene 7334	20402	0.25
chr8_14996081_14996572	0.66	Arhgef10	Rho guanine nucleotide exchange factor (GEF) 10	190	0.91
chr10_98624940_98625347	0.66	Gm5427	predicted gene 5427	74567	0.11
chr5_65157791_65158129	0.65	Klhl5	kelch-like 5	1890	0.3
chr6_32780587_32780883	0.65	Chchd3	coiled-coil-helix-coiled-coil-helix domain containing 3	23257	0.21
chr3_44001981_44002132	0.65	Gm37746	predicted gene, 37746	46335	0.18
chr2_79511880_79512425	0.65	Cerkl	ceramide kinase-like	55367	0.13
chr11_49185940_49186568	0.65	Btnl9	butyrophilin-like 9	783	0.5
chr7_83881977_83882131	0.64	Tlnrd1	talin rod domain containing 1	2251	0.16
chr18_80608643_80609126	0.64	Nfatc1	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1	91	0.97
chr6_5005475_5006221	0.64	Gm26556	predicted gene, 26556	46865	0.12
chr2_168589071_168590755	0.64	Nfatc2	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2	278	0.93
chr9_25255721_25255939	0.64	Septin7	septin 7	3164	0.23
chr10_12019489_12019746	0.64	Gm48721	predicted gene, 48721	9846	0.2
chr8_40964050_40964403	0.64	Mtus1	mitochondrial tumor suppressor 1	35979	0.12
chr13_107100937_107101851	0.63	Gm31452	predicted gene, 31452	37699	0.14
chr15_88758591_88758769	0.63	Zbed4	zinc finger, BED type containing 4	6920	0.18
chr5_90772565_90772911	0.63	Pf4	platelet factor 4	153	0.91
chr10_19613570_19613755	0.63	Ifngr1	interferon gamma receptor 1	7743	0.17
chr11_116108498_116109194	0.62	Trim47	tripartite motif-containing 47	727	0.48
chr3_8830830_8831235	0.62	Gm15467	predicted gene 15467	50167	0.11
chr6_143414967_143415230	0.62	Gm23272	predicted gene, 23272	50299	0.16
chrX_99042650_99043872	0.61	Stard8	START domain containing 8	680	0.74
chr13_110400077_110400840	0.61	Plk2	polo like kinase 2	2661	0.34
chr19_11484214_11484365	0.61	BE692007	expressed sequence BE692007	246	0.82
chr15_55120737_55121109	0.61	Gm9920	predicted gene 9920	7246	0.16
chr4_139853168_139853461	0.61	Pax7	paired box 7	19786	0.18
chr7_19011655_19012657	0.61	Irf2bp1	interferon regulatory factor 2 binding protein 1	8112	0.07
chr15_7222960_7224074	0.61	Egflam	EGF-like, fibronectin type III and laminin G domains	448	0.88
chr18_61785451_61786937	0.61	Afap1l1	actin filament associated protein 1-like 1	417	0.83
chr8_68556575_68557433	0.60	Csgalnact1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	27117	0.2
chr10_111594457_111595800	0.60	4933440J02Rik	RIKEN cDNA 4933440J02 gene	855	0.55
chr6_142980378_142980752	0.60	A930014E10Rik	RIKEN cDNA A930014E10 gene	8813	0.14
chr12_21755400_21755551	0.60	Mrto4-ps2	mRNA turnover 4, pseudogene 2	21232	0.25
chr13_63247351_63247556	0.60	Gm47586	predicted gene, 47586	3232	0.13
chrX_134275786_134276085	0.60	Trmt2b	TRM2 tRNA methyltransferase 2B	985	0.51
chr3_143742898_143743955	0.59	Gm42705	predicted gene 42705	49	0.97
chr5_62764802_62765190	0.59	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	1124	0.61
chrX_57337845_57338237	0.59	Arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	465	0.83
chr2_127728515_127728972	0.59	Mall	mal, T cell differentiation protein-like	1189	0.38
chr10_77449173_77450128	0.59	Gm35920	predicted gene, 35920	8267	0.17
chr7_34745303_34745454	0.59	Chst8	carbohydrate sulfotransferase 8	8434	0.21
chr17_69121690_69122267	0.58	Epb41l3	erythrocyte membrane protein band 4.1 like 3	5022	0.32
chr8_85360708_85361016	0.58	Mylk3	myosin light chain kinase 3	4462	0.15
chr8_34622034_34622185	0.58	Gm34096	predicted gene, 34096	13804	0.17
chr16_78456546_78456702	0.58	Gm49603	predicted gene, 49603	23915	0.15
chr16_23993405_23994148	0.58	Bcl6	B cell leukemia/lymphoma 6	4924	0.18
chr7_96899195_96899433	0.58	Gm22226	predicted gene, 22226	20788	0.15
chr3_90614243_90615549	0.58	S100a6	S100 calcium binding protein A6 (calcyclin)	1136	0.26
chr2_76808432_76808950	0.57	Ttn	titin	17851	0.23
chr5_88928873_88929323	0.57	Slc4a4	solute carrier family 4 (anion exchanger), member 4	5434	0.28
chrX_42540237_42540930	0.57	Sh2d1a	SH2 domain containing 1A	13998	0.25
chr17_34693537_34693688	0.56	Gm24389	predicted gene, 24389	5810	0.07
chr15_54413168_54413466	0.56	Colec10	collectin sub-family member 10	2543	0.32
chr1_168423148_168423974	0.56	Pbx1	pre B cell leukemia homeobox 1	7943	0.26
chr2_176121352_176121707	0.56	Gm16357	predicted gene 16357	3663	0.21
chr14_54959915_54960463	0.55	Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	2282	0.1
chr1_189340106_189340450	0.55	Kcnk2	potassium channel, subfamily K, member 2	3077	0.24
chr4_15883184_15883580	0.55	Calb1	calbindin 1	2075	0.27
chr4_106489848_106489999	0.55	Bsnd	barttin CLCNK type accessory beta subunit	2360	0.2
chr15_5927691_5927842	0.55	Gm49095	predicted gene, 49095	23678	0.2
chr6_74588312_74588463	0.55	Gm22254	predicted gene, 22254	83223	0.11
chr4_143238489_143238893	0.55	Eef2-ps2	eukaryotic translation elongation factor 2, pseudogene 2	4677	0.17
chr12_36137152_36137570	0.54	Gm48369	predicted gene, 48369	10561	0.12
chr4_16168304_16169243	0.54	A530072M11Rik	RIKEN cDNA gene A530072M11	4663	0.18
chr2_177032666_177033048	0.54	Gm14402	predicted gene 14402	202	0.91
chr15_7145070_7145221	0.54	Lifr	LIF receptor alpha	4596	0.31
chr5_24365290_24365969	0.54	Nos3	nitric oxide synthase 3, endothelial cell	819	0.41
chr6_59022486_59023190	0.53	Fam13a	family with sequence similarity 13, member A	1502	0.36
chr10_4611597_4612860	0.53	Esr1	estrogen receptor 1 (alpha)	207	0.95
chr12_40381138_40381829	0.53	Zfp277	zinc finger protein 277	18599	0.22
chr1_43182605_43182756	0.53	Gm8210	predicted pseudogene 8210	6476	0.19
chr6_86480161_86480975	0.53	A430078I02Rik	RIKEN cDNA A430078I02 gene	202	0.86
chr10_68541127_68542141	0.53	Cabcoco1	ciliary associated calcium binding coiled-coil 1	262	0.94
chr11_89066018_89066308	0.52	Dgkeos	diacylglycerol kinase, epsilon, opposite strand	75	0.91
chr3_101598645_101599448	0.52	Gm42941	predicted gene 42941	1916	0.31
chr8_11331313_11331580	0.52	Col4a1	collagen, type IV, alpha 1	18620	0.15
chr10_5287995_5289689	0.52	Gm23573	predicted gene, 23573	68331	0.12
chr6_91960417_91960897	0.52	4930590J08Rik	RIKEN cDNA 4930590J08 gene	16393	0.13
chr3_152191751_152192635	0.52	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	1652	0.26
chr4_141304021_141304172	0.52	Epha2	Eph receptor A2	1689	0.23
chr17_45620159_45620310	0.52	Gm25008	predicted gene, 25008	445	0.69
chr15_89425017_89425997	0.51	Cpt1b	carnitine palmitoyltransferase 1b, muscle	288	0.74
chr3_40509511_40509727	0.51	1700017G19Rik	RIKEN cDNA 1700017G19 gene	155	0.96
chr8_77523888_77524583	0.51	0610038B21Rik	RIKEN cDNA 0610038B21 gene	6120	0.15
chr15_91028535_91029324	0.51	Kif21a	kinesin family member 21A	20889	0.18
chr2_176831033_176831392	0.51	Gm14408	predicted gene 14408	72	0.97
chr3_41173045_41173450	0.51	Gm40038	predicted gene, 40038	584	0.8
chr7_132656285_132656853	0.51	Gm15582	predicted gene 15582	3315	0.23
chr4_63151303_63151507	0.51	Ambp	alpha 1 microglobulin/bikunin precursor	2768	0.24
chr15_40354440_40354591	0.51	Gm41311	predicted gene, 41311	11255	0.28
chr1_194940483_194941153	0.51	Cd34	CD34 antigen	1823	0.26
chr16_31695067_31695951	0.51	Dlg1	discs large MAGUK scaffold protein 1	11243	0.15
chr14_119260402_119261033	0.51	Gm6087	predicted gene 6087	17707	0.26
chr7_135604964_135605508	0.50	Ptpre	protein tyrosine phosphatase, receptor type, E	592	0.74
chr9_69092316_69092646	0.50	Rora	RAR-related orphan receptor alpha	103060	0.08
chr13_46503428_46503590	0.50	Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	1343	0.34
chr12_19201995_19202146	0.50	Gm48528	predicted gene, 48528	16012	0.14
chr17_26503687_26504320	0.50	Gm34455	predicted gene, 34455	803	0.47
chr13_59970938_59972210	0.50	Gm48390	predicted gene, 48390	52136	0.09
chr3_38015645_38016389	0.50	Gm22899	predicted gene, 22899	20782	0.16
chr13_38602280_38602560	0.50	Gm47400	predicted gene, 47400	32551	0.1
chr5_124960229_124960932	0.50	Rflna	refilin A	42641	0.13
chr5_77579867_77580744	0.50	Pea15b	phosphoprotein enriched in astrocytes 15B	68557	0.09
chr9_70567831_70568043	0.49	Sltm	SAFB-like, transcription modulator	7471	0.16
chr3_93568427_93569206	0.48	S100a10	S100 calcium binding protein A10 (calpactin)	8089	0.13
chr6_88189310_88190735	0.48	Gm38708	predicted gene, 38708	659	0.6
chr14_93306296_93306447	0.48	Gm48964	predicted gene, 48964	4766	0.32
chr10_89453189_89453411	0.48	Gas2l3	growth arrest-specific 2 like 3	9333	0.24
chr10_95725993_95726144	0.48	1110019B22Rik	RIKEN cDNA 1110019B22 gene	3568	0.14
chr8_11260160_11260311	0.48	Col4a1	collagen, type IV, alpha 1	14630	0.16
chr5_81509100_81509275	0.47	Gm43084	predicted gene 43084	26539	0.26
chr14_101886945_101887764	0.47	Lmo7	LIM domain only 7	3235	0.35
chr9_118488682_118489383	0.47	Gm33460	predicted gene, 33460	67	0.96
chr11_78984345_78985263	0.47	Lgals9	lectin, galactose binding, soluble 9	27	0.98
chr2_68435653_68436705	0.47	Stk39	serine/threonine kinase 39	35761	0.16
chr2_131129425_131129576	0.47	Hspa12b	heat shock protein 12B	2006	0.18
chr9_32341364_32342112	0.47	Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	2499	0.25
chr6_23462582_23462958	0.47	Gm27959	predicted gene, 27959	56976	0.14
chr19_53325039_53326410	0.46	Gm30541	predicted gene, 30541	1	0.97
chr17_86364752_86364903	0.46	2010106C02Rik	RIKEN cDNA 2010106C02 gene	77649	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfat5

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3	1.3	GO:0086064	cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.3	0.8	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.2	0.7	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.2	0.6	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2	0.6	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2	0.8	GO:1900212	mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.2	0.5	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.2	0.6	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.2	0.5	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.2	0.9	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.1	0.1	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.1	1.1	GO:0060539	diaphragm development(GO:0060539)
0.1	1.1	GO:0030953	astral microtubule organization(GO:0030953)
0.1	0.3	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.3	GO:0048769	sarcomerogenesis(GO:0048769)
0.1	0.3	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.1	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	0.3	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.3	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.1	0.3	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1	0.2	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
0.1	0.2	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.3	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	0.4	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	0.2	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.1	0.2	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1	0.3	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	1.6	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.1	0.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.3	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.1	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.3	GO:1903367	positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1	0.3	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.2	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.1	0.2	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1	0.2	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	0.2	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1	0.3	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.1	0.3	GO:0035902	response to immobilization stress(GO:0035902)
0.1	0.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.9	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.3	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	0.2	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.1	0.2	GO:0006083	acetate metabolic process(GO:0006083)
0.1	0.4	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.3	GO:0044539	long-chain fatty acid import(GO:0044539)
0.1	0.2	GO:0060486	Clara cell differentiation(GO:0060486)
0.1	0.2	GO:0021824	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1	0.2	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.6	GO:2000194	regulation of female gonad development(GO:2000194)
0.1	0.2	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.2	GO:0036394	amylase secretion(GO:0036394)
0.1	0.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	0.3	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1	0.2	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.2	GO:0032264	IMP salvage(GO:0032264)
0.0	0.3	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0	0.1	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.0	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.2	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.1	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.0	0.5	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.3	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.3	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.7	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.2	GO:2000650	negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0	0.1	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.2	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.3	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0	0.1	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.3	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0032763	regulation of mast cell cytokine production(GO:0032763)
0.0	0.1	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0	0.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.5	GO:1901739	regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.0	0.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.1	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.3	GO:0043144	snoRNA processing(GO:0043144)
0.0	0.1	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0	0.1	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.3	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.1	GO:0021764	amygdala development(GO:0021764)
0.0	0.1	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.1	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.1	GO:0003096	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0	0.0	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.0	0.3	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.2	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.2	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.5	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.0	0.1	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.0	0.1	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.1	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.0	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.0	GO:0003166	bundle of His development(GO:0003166)
0.0	0.0	GO:1900126	regulation of hyaluronan biosynthetic process(GO:1900125) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.6	GO:0033003	regulation of mast cell activation(GO:0033003)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.3	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.1	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.0	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.0	0.1	GO:0001765	membrane raft assembly(GO:0001765)
0.0	0.3	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0031077	post-embryonic camera-type eye development(GO:0031077)
0.0	0.2	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.0	GO:1904180	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.3	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.0	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	1.1	GO:0050818	regulation of coagulation(GO:0050818)
0.0	0.1	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0006848	pyruvate transport(GO:0006848)
0.0	0.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0002551	mast cell chemotaxis(GO:0002551)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.0	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.0	GO:1905065	positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:2000794	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.2	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.0	GO:2000611	positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0046959	habituation(GO:0046959)
0.0	0.1	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.1	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.0	GO:1900084	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0035912	dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0	0.0	GO:0060558	regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.0	0.0	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.1	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.0	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.4	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.1	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.0	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0015755	fructose transport(GO:0015755)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.0	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.1	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0	0.1	GO:0072710	response to hydroxyurea(GO:0072710) cellular response to hydroxyurea(GO:0072711)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.1	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.1	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.0	GO:0035993	deltoid tuberosity development(GO:0035993)
0.0	0.1	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0015822	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0	0.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.0	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0001692	histamine metabolic process(GO:0001692)
0.0	0.1	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.0	0.1	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0042407	cristae formation(GO:0042407)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.0	GO:0070488	neutrophil aggregation(GO:0070488)
0.0	0.0	GO:0060137	maternal process involved in parturition(GO:0060137)
0.0	0.2	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.0	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.0	GO:0043380	regulation of memory T cell differentiation(GO:0043380)
0.0	0.0	GO:1902475	L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.1	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:0032570	response to progesterone(GO:0032570)
0.0	0.0	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.3	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0000436	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.0	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.0	GO:0003163	sinoatrial node development(GO:0003163)
0.0	0.1	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.1	0.8	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.3	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	1.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.2	GO:0031523	Myb complex(GO:0031523)
0.1	0.6	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.4	GO:0098651	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.3	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	2.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.7	GO:0043034	costamere(GO:0043034)
0.0	0.4	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.3	GO:0071546	pi-body(GO:0071546)
0.0	0.6	GO:0031091	platelet alpha granule(GO:0031091)
0.0	0.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.2	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.3	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.0	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.0	GO:0032437	cuticular plate(GO:0032437)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005608	laminin-3 complex(GO:0005608)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0097449	astrocyte projection(GO:0097449)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.0	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.1	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.5	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.4	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.0	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.8	GO:0005901	caveola(GO:0005901)
0.0	0.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.7	GO:0030018	Z disc(GO:0030018)
0.0	0.4	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0014704	intercalated disc(GO:0014704)
0.0	0.3	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.0	GO:0005726	perichromatin fibrils(GO:0005726)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.7	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2	1.5	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	1.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.2	0.6	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	0.6	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.2	0.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.9	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.3	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.5	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.9	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.4	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.3	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.3	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.6	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	0.3	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	0.8	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.2	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.2	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	0.4	GO:0016936	galactoside binding(GO:0016936)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0019862	IgA binding(GO:0019862)
0.1	0.3	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	0.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.2	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.2	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1	0.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.5	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.1	0.2	GO:0043199	sulfate binding(GO:0043199)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.3	GO:0043731	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.4	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.2	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.2	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.2	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.7	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.2	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	1.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0002134	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.6	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.5	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0043912	D-lysine oxidase activity(GO:0043912)
0.0	0.0	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0001884	pyrimidine nucleoside binding(GO:0001884)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.0	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.1	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	1.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	1.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.4	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.4	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.6	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	1.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	0.8	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.6	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.1	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.6	REACTOME SEMAPHORIN INTERACTIONS	Genes involved in Semaphorin interactions
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling

Results for Nfat5

Z-value: 0.79

Motif logo

Transcription factors associated with Nfat5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nfat5 motif across conditions

Conditions sorted by the z-value of the Nfat5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfat5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: