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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Nfe2l1_Mafg

Z-value: 0.40

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Transcription factors associated with Nfe2l1_Mafg

Gene Symbol Gene ID Gene Info
Nfe2l1
ENSMUSG00000038615.11 nuclear factor, erythroid derived 2,-like 1
Mafg
ENSMUSG00000051510.7 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
Mafg
ENSMUSG00000053906.4 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_120635927_120636078Mafg24020.087462-0.401.4e-03Click!
chr11_120637299_120637552Mafg38250.065678-0.191.5e-01Click!
chr11_120633726_120633919Mafg2220.7739770.162.2e-01Click!
chr11_120632083_120632234Mafg13610.1542420.152.4e-01Click!
chr11_120628347_120628498Mafg17260.1146800.123.5e-01Click!
chr11_96837393_96837544Nfe2l175000.097092-0.453.4e-04Click!
chr11_96818178_96818461Nfe2l144060.116272-0.392.3e-03Click!
chr11_96830243_96830655Nfe2l14810.6606340.292.4e-02Click!
chr11_96828944_96829908Nfe2l1750.9437840.228.5e-02Click!
chr11_96823513_96824552Nfe2l1190.954431-0.211.0e-01Click!

Activity of the Nfe2l1_Mafg motif across conditions

Conditions sorted by the z-value of the Nfe2l1_Mafg motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_75577269_75578512 0.25 Kit
 KIT proto-oncogene receptor tyrosine kinase
 2935
 0.29
chr13_109928298_109928867 0.22 Pde4d
 phosphodiesterase 4D, cAMP specific
 1738
 0.46
chr16_91466275_91466861 0.22 Gm49626
 predicted gene, 49626
 1443
 0.19
chr15_78116860_78117881 0.22 A730060N03Rik
 RIKEN cDNA A730060N03 gene
 2336
 0.22
chr11_101011506_101011900 0.18 Atp6v0a1
 ATPase, H+ transporting, lysosomal V0 subunit A1
 118
 0.94
chr9_95561747_95561983 0.18 Paqr9
 progestin and adipoQ receptor family member IX
 2208
 0.22
chr9_74977325_74977617 0.18 Fam214a
 family with sequence similarity 214, member A
 1360
 0.45
chrX_165326400_165326667 0.17 Glra2
 glycine receptor, alpha 2 subunit
 860
 0.76
chr15_13367879_13368144 0.17 Gm8238
 predicted gene 8238
 50845
 0.16
chr4_13754294_13755025 0.17 Runx1t1
 RUNX1 translocation partner 1
 3362
 0.37
chr1_136132801_136134260 0.17 Kif21b
 kinesin family member 21B
 2076
 0.19
chr9_10903129_10903698 0.16 Gm32710
 predicted gene, 32710
 932
 0.44
chr1_164454554_164455430 0.16 Atp1b1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
 1215
 0.39
chr11_61453075_61454398 0.15 Rnf112
 ring finger protein 112
 183
 0.92
chr11_62005417_62006894 0.15 Specc1
 sperm antigen with calponin homology and coiled-coil domains 1
 805
 0.61
chr10_101682665_101683088 0.15 Mgat4c
 MGAT4 family, member C
 1130
 0.6
chr15_85675143_85675686 0.15 Lncppara
 long noncoding RNA near Ppara
 21798
 0.12
chr6_28827182_28827949 0.14 Lrrc4
 leucine rich repeat containing 4
 2780
 0.27
chr9_95562029_95562400 0.14 Paqr9
 progestin and adipoQ receptor family member IX
 2557
 0.2
chr4_82589377_82589629 0.14 Gm11267
 predicted gene 11267
 2184
 0.36
chr10_90577565_90578158 0.14 Anks1b
 ankyrin repeat and sterile alpha motif domain containing 1B
 869
 0.72
chr8_86615787_86615938 0.13 Lonp2
 lon peptidase 2, peroxisomal
 8181
 0.17
chr1_146500124_146500296 0.13 Brinp3
 bone morphogenetic protein/retinoic acid inducible neural specific 3
 2472
 0.28
chr2_97470022_97470462 0.13 Lrrc4c
 leucine rich repeat containing 4C
 2153
 0.46
chr9_21196536_21198489 0.13 Pde4a
 phosphodiesterase 4A, cAMP specific
 807
 0.45
chr10_77112255_77113959 0.13 Col18a1
 collagen, type XVIII, alpha 1
 598
 0.73
chr12_71048661_71048812 0.13 Arid4a
 AT rich interactive domain 4A (RBP1-like)
 395
 0.84
chr9_112232861_112233588 0.13 Arpp21
 cyclic AMP-regulated phosphoprotein, 21
 402
 0.75
chr5_43236032_43236320 0.13 Gm7854
 predicted gene 7854
 821
 0.45
chr18_31445651_31446131 0.13 Syt4
 synaptotagmin IV
 1515
 0.34
chr3_80798105_80798468 0.13 Gria2
 glutamate receptor, ionotropic, AMPA2 (alpha 2)
 4293
 0.29
chr6_87424489_87424700 0.12 Bmp10
 bone morphogenetic protein 10
 4400
 0.17
chr11_28582033_28582291 0.12 Ccdc85a
 coiled-coil domain containing 85A
 1833
 0.45
chr8_54957960_54958420 0.12 Gm45263
 predicted gene 45263
 1629
 0.32
chr1_173941256_173941415 0.12 Ifi203
 interferon activated gene 203
 1119
 0.39
chr8_9767652_9767828 0.12 Fam155a
 family with sequence similarity 155, member A
 2364
 0.22
chr13_69736057_69736269 0.12 Ube2ql1
 ubiquitin-conjugating enzyme E2Q family-like 1
 3726
 0.16
chr5_84412572_84412901 0.12 Epha5
 Eph receptor A5
 4070
 0.29
chr6_55338294_55340060 0.12 Aqp1
 aquaporin 1
 2745
 0.22
chr16_97168993_97169144 0.12 Dscam
 DS cell adhesion molecule
 1684
 0.52
chr3_136673390_136673717 0.12 Ppp3ca
 protein phosphatase 3, catalytic subunit, alpha isoform
 2783
 0.31
chr7_103825389_103825783 0.12 Hbb-bs
 hemoglobin, beta adult s chain
 2139
 0.11
chr19_5842574_5845856 0.12 Neat1
 nuclear paraspeckle assembly transcript 1 (non-protein coding)
 1044
 0.25
chr4_36948006_36948454 0.12 Lingo2
 leucine rich repeat and Ig domain containing 2
 2237
 0.35
chr4_70532291_70532442 0.11 Megf9
 multiple EGF-like-domains 9
 2562
 0.43
chr1_124042617_124042950 0.11 Dpp10
 dipeptidylpeptidase 10
 2380
 0.44
chr11_46440995_46441189 0.11 Med7
 mediator complex subunit 7
 1440
 0.31
chr5_135806693_135807939 0.11 Srrm3
 serine/arginine repetitive matrix 3
 419
 0.73
chr9_19994680_19994831 0.11 Olfr864-ps1
 olfactory receptor 864, pseudogene 1
 1678
 0.24
chr14_55054880_55055132 0.11 Gm20687
 predicted gene 20687
 49
 0.92
chr1_81076133_81076284 0.11 Nyap2
 neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
 742
 0.79
chr6_142962344_142962495 0.11 St8sia1
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
 1722
 0.29
chr6_137253502_137253687 0.11 Ptpro
 protein tyrosine phosphatase, receptor type, O
 1129
 0.6
chr1_173801485_173801725 0.11 Ifi203-ps
 interferon activated gene 203, pseudogene
 3335
 0.17
chr14_60381648_60381975 0.11 Amer2
 APC membrane recruitment 2
 3525
 0.27
chr18_69599939_69600665 0.11 Tcf4
 transcription factor 4
 766
 0.75
chr11_104234777_104235157 0.11 Mapt
 microtubule-associated protein tau
 3383
 0.19
chr12_108605770_108606876 0.11 Evl
 Ena-vasodilator stimulated phosphoprotein
 557
 0.74
chr7_80200040_80200211 0.11 Sema4b
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
 1589
 0.23
chr18_31442020_31442171 0.11 Gm26658
 predicted gene, 26658
 1777
 0.3
chr7_61981610_61982350 0.11 A330076H08Rik
 RIKEN cDNA A330076H08 gene
 323
 0.52
chr8_46472677_46473081 0.11 Gm45244
 predicted gene 45244
 711
 0.56
chr16_76318105_76318441 0.10 Nrip1
 nuclear receptor interacting protein 1
 5385
 0.27
chr14_34675529_34675753 0.10 Wapl
 WAPL cohesin release factor
 1468
 0.27
chr7_51630779_51630985 0.10 Gm45072
 predicted gene 45072
 843
 0.52
chr11_31874060_31874636 0.10 Cpeb4
 cytoplasmic polyadenylation element binding protein 4
 1073
 0.55
chr18_43390784_43391261 0.10 Dpysl3
 dihydropyrimidinase-like 3
 2355
 0.34
chr7_131968717_131968868 0.10 Gpr26
 G protein-coupled receptor 26
 2332
 0.32
chr2_103958009_103958847 0.10 Lmo2
 LIM domain only 2
 433
 0.78
chr3_149069217_149069368 0.10 Gm25127
 predicted gene, 25127
 40360
 0.16
chr10_12611642_12612156 0.10 Utrn
 utrophin
 2932
 0.38
chr2_138277835_138280637 0.10 Btbd3
 BTB (POZ) domain containing 3
 743
 0.81
chr14_108909489_108909909 0.10 Slitrk1
 SLIT and NTRK-like family, member 1
 4459
 0.37
chr9_37527353_37531611 0.10 Esam
 endothelial cell-specific adhesion molecule
 701
 0.51
chr3_89522754_89523224 0.10 Kcnn3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
 2825
 0.22
chr9_68888905_68889137 0.10 Rora
 RAR-related orphan receptor alpha
 233718
 0.02
chr16_92824962_92826063 0.10 Runx1
 runt related transcription factor 1
 266
 0.94
chr7_87588060_87588319 0.10 Grm5
 glutamate receptor, metabotropic 5
 3791
 0.35
chr13_42711375_42711526 0.10 Phactr1
 phosphatase and actin regulator 1
 1869
 0.43
chr3_136672766_136672917 0.10 Ppp3ca
 protein phosphatase 3, catalytic subunit, alpha isoform
 2071
 0.37
chr18_62176067_62177775 0.10 Adrb2
 adrenergic receptor, beta 2
 3038
 0.24
chr2_134825693_134826026 0.10 Gm14036
 predicted gene 14036
 21910
 0.2
chr8_46496910_46497239 0.10 Acsl1
 acyl-CoA synthetase long-chain family member 1
 4242
 0.18
chr6_67034885_67035063 0.10 E230016M11Rik
 RIKEN cDNA E230016M11 gene
 1625
 0.23
chr8_90869910_90870860 0.10 Gm45640
 predicted gene 45640
 6196
 0.14
chr15_54572723_54573229 0.10 Mal2
 mal, T cell differentiation protein 2
 1784
 0.45
chr2_94055302_94055453 0.10 Hsd17b12
 hydroxysteroid (17-beta) dehydrogenase 12
 11092
 0.18
chrX_23283125_23283785 0.10 Klhl13
 kelch-like 13
 1374
 0.57
chr14_101841859_101842332 0.10 Lmo7
 LIM domain only 7
 1276
 0.57
chr8_109245493_109246323 0.10 D030068K23Rik
 RIKEN cDNA D030068K23 gene
 3958
 0.33
chr8_61515132_61515409 0.10 Palld
 palladin, cytoskeletal associated protein
 630
 0.77
chr15_59079090_59079241 0.10 Mtss1
 MTSS I-BAR domain containing 1
 2824
 0.32
chrX_144686917_144687223 0.09 Trpc5
 transient receptor potential cation channel, subfamily C, member 5
 933
 0.55
chr16_42907540_42907820 0.09 Zbtb20
 zinc finger and BTB domain containing 20
 28
 0.98
chrX_111443823_111443974 0.09 Rps6ka6
 ribosomal protein S6 kinase polypeptide 6
 18741
 0.28
chr1_79437828_79438003 0.09 Scg2
 secretogranin II
 2127
 0.4
chr8_121730928_121732115 0.09 Jph3
 junctophilin 3
 954
 0.49
chr13_20474951_20475127 0.09 Gm32036
 predicted gene, 32036
 1549
 0.33
chr16_46008622_46009173 0.09 Plcxd2
 phosphatidylinositol-specific phospholipase C, X domain containing 2
 1321
 0.41
chr3_96181539_96182795 0.09 Sv2a
 synaptic vesicle glycoprotein 2 a
 1016
 0.22
chr2_82055274_82055801 0.09 Zfp804a
 zinc finger protein 804A
 2315
 0.43
chr3_152866007_152866344 0.09 Gm16232
 predicted gene 16232
 10042
 0.2
chr10_81426043_81427197 0.09 Nfic
 nuclear factor I/C
 494
 0.54
chr11_87762635_87763192 0.09 Tspoap1
 TSPO associated protein 1
 1818
 0.17
chr11_90196330_90196540 0.09 Gm45883
 predicted gene 45883
 8260
 0.16
chr5_66678971_66679451 0.09 Uchl1
 ubiquitin carboxy-terminal hydrolase L1
 2319
 0.2
chr13_117022581_117022756 0.09 Parp8
 poly (ADP-ribose) polymerase family, member 8
 2605
 0.3
chr19_38265533_38266016 0.09 Lgi1
 leucine-rich repeat LGI family, member 1
 364
 0.85
chr1_3667888_3668100 0.09 Xkr4
 X-linked Kx blood group related 4
 3504
 0.21
chr15_78404813_78404964 0.09 Tst
 thiosulfate sulfurtransferase, mitochondrial
 964
 0.32
chr12_5372599_5372750 0.09 Klhl29
 kelch-like 29
 3008
 0.28
chr11_115511512_115512231 0.09 Jpt1
 Jupiter microtubule associated homolog 1
 2245
 0.14
chr1_70725543_70726581 0.09 Vwc2l
 von Willebrand factor C domain-containing protein 2-like
 139
 0.98
chr13_59819810_59820064 0.09 Tut7
 terminal uridylyl transferase 7
 2651
 0.15
chr2_23562980_23563209 0.09 Spopl
 speckle-type BTB/POZ protein-like
 8884
 0.24
chr16_77236514_77236677 0.09 Mir99ahg
 Mir99a and Mirlet7c-1 host gene (non-protein coding)
 276
 0.93
chr18_56922535_56922923 0.09 Marchf3
 membrane associated ring-CH-type finger 3
 2786
 0.27
chr12_56253431_56254088 0.09 Gm19990
 predicted gene, 19990
 516
 0.47
chr7_122673354_122673569 0.09 Cacng3
 calcium channel, voltage-dependent, gamma subunit 3
 2043
 0.32
chr6_120819578_120819729 0.09 Atp6v1e1
 ATPase, H+ transporting, lysosomal V1 subunit E1
 1254
 0.37
chr15_36275796_36275947 0.09 Rnf19a
 ring finger protein 19A
 7227
 0.13
chr5_151188598_151188749 0.09 Stard13
 StAR-related lipid transfer (START) domain containing 13
 1477
 0.48
chr14_64575803_64576191 0.09 Mir124a-1hg
 Mir124-1 host gene (non-protein coding)
 11334
 0.15
chr6_24047175_24047352 0.09 Slc13a1
 solute carrier family 13 (sodium/sulfate symporters), member 1
 61308
 0.12
chr4_32862939_32864770 0.09 Ankrd6
 ankyrin repeat domain 6
 3171
 0.24
chr8_121904943_121905414 0.09 Slc7a5
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
 2516
 0.15
chr2_148404766_148404943 0.09 Thbd
 thrombomodulin
 3334
 0.2
chr10_111166520_111166791 0.09 Osbpl8
 oxysterol binding protein-like 8
 1853
 0.27
chr3_94412462_94413013 0.09 1700040D17Rik
 RIKEN cDNA 1700040D17 gene
 182
 0.67
chr15_78571734_78572724 0.09 Rac2
 Rac family small GTPase 2
 552
 0.62
chr1_75277211_75278430 0.09 Resp18
 regulated endocrine-specific protein 18
 464
 0.62
chr4_138251495_138252773 0.09 Sh2d5
 SH2 domain containing 5
 1670
 0.22
chr19_26751454_26751605 0.09 Smarca2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 407
 0.88
chr19_8840785_8841292 0.09 Bscl2
 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
 503
 0.44
chr7_126823319_126824529 0.09 Fam57b
 family with sequence similarity 57, member B
 621
 0.41
chr5_9721072_9721322 0.09 Grm3
 glutamate receptor, metabotropic 3
 3973
 0.27
chr8_93814307_93815014 0.09 4930488L21Rik
 RIKEN cDNA 4930488L21 gene
 938
 0.54
chrX_85870254_85870648 0.09 5430427O19Rik
 RIKEN cDNA 5430427O19 gene
 97
 0.97
chr1_162898137_162898420 0.09 Fmo2
 flavin containing monooxygenase 2
 206
 0.94
chr2_60960139_60960473 0.09 Rbms1
 RNA binding motif, single stranded interacting protein 1
 2886
 0.3
chr2_24385363_24386049 0.09 Psd4
 pleckstrin and Sec7 domain containing 4
 353
 0.84
chr5_150261018_150262108 0.09 Fry
 FRY microtubule binding protein
 1796
 0.34
chr6_67228511_67229348 0.09 Gm44052
 predicted gene, 44052
 6385
 0.13
chr1_172501767_172503923 0.09 Tagln2
 transgelin 2
 1593
 0.22
chr11_15096657_15096828 0.09 Gm12009
 predicted gene 12009
 47584
 0.2
chr3_51636519_51637197 0.08 Gm38247
 predicted gene, 38247
 70
 0.96
chr2_6870837_6870988 0.08 Celf2
 CUGBP, Elav-like family member 2
 1060
 0.55
chr1_38012822_38013138 0.08 Eif5b
 eukaryotic translation initiation factor 5B
 14851
 0.14
chr1_140182842_140183316 0.08 Cfh
 complement component factor h
 201
 0.96
chr11_20331076_20331227 0.08 Slc1a4
 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
 1533
 0.37
chr15_37457581_37457955 0.08 Ncald
 neurocalcin delta
 773
 0.56
chrX_167207304_167207608 0.08 Tmsb4x
 thymosin, beta 4, X chromosome
 1371
 0.45
chr11_43834010_43835381 0.08 Adra1b
 adrenergic receptor, alpha 1b
 1637
 0.47
chr10_33256172_33256374 0.08 D830005E20Rik
 RIKEN cDNA D830005E20 gene
 84
 0.97
chr1_115687470_115687621 0.08 Cntnap5a
 contactin associated protein-like 5A
 2789
 0.31
chr17_44809334_44809504 0.08 Runx2
 runt related transcription factor 2
 4807
 0.23
chr15_98674837_98676155 0.08 Rnd1
 Rho family GTPase 1
 1962
 0.18
chr17_91085493_91086001 0.08 Gm47307
 predicted gene, 47307
 2659
 0.21
chr3_14890853_14891237 0.08 Car2
 carbonic anhydrase 2
 4406
 0.22
chr14_101842332_101842898 0.08 Lmo7
 LIM domain only 7
 1796
 0.46
chr16_46008308_46008480 0.08 Plcxd2
 phosphatidylinositol-specific phospholipase C, X domain containing 2
 1824
 0.32
chr13_90844060_90844211 0.08 Gm18518
 predicted gene, 18518
 23471
 0.19
chr6_39874717_39875333 0.08 Tmem178b
 transmembrane protein 178B
 1954
 0.27
chrX_93430021_93430176 0.08 Pola1
 polymerase (DNA directed), alpha 1
 60848
 0.12
chr13_116298582_116298733 0.08 Isl1
 ISL1 transcription factor, LIM/homeodomain
 4694
 0.26
chr14_27876139_27876947 0.08 Erc2
 ELKS/RAB6-interacting/CAST family member 2
 129
 0.75
chr3_4800881_4801176 0.08 1110015O18Rik
 RIKEN cDNA 1110015O18 gene
 1535
 0.47
chr16_20098725_20098876 0.08 Klhl24
 kelch-like 24
 1208
 0.49
chr13_116214509_116214705 0.08 Rpl34-ps2
 ribosomal protein L34, pseudogene 2
 60826
 0.13
chr5_146232824_146233169 0.08 Cdk8
 cyclin-dependent kinase 8
 1611
 0.25
chr10_96623801_96623952 0.08 Btg1
 BTG anti-proliferation factor 1
 6322
 0.22
chr16_31423409_31423642 0.08 Bdh1
 3-hydroxybutyrate dehydrogenase, type 1
 1245
 0.34
chr12_117805814_117806560 0.08 Cdca7l
 cell division cycle associated 7 like
 1898
 0.37
chr16_36366547_36366698 0.08 Gm15845
 predicted gene 15845
 448
 0.53
chrX_95194864_95195015 0.08 Arhgef9
 CDC42 guanine nucleotide exchange factor (GEF) 9
 1513
 0.42
chr10_63977869_63978469 0.08 Gm10118
 predicted gene 10118
 50735
 0.17
chr12_113426567_113426898 0.08 Gm22175
 predicted gene, 22175
 1505
 0.16
chr10_42273694_42273969 0.08 Foxo3
 forkhead box O3
 2865
 0.34
chr2_103971594_103971745 0.08 Lmo2
 LIM domain only 2
 490
 0.74
chr14_70618232_70619317 0.08 Dmtn
 dematin actin binding protein
 229
 0.88
chrX_88113433_88114223 0.08 Il1rapl1
 interleukin 1 receptor accessory protein-like 1
 1817
 0.46
chr1_130721109_130721366 0.08 Yod1
 YOD1 deubiquitinase
 3910
 0.11
chr14_27380191_27380512 0.08 Gm23633
 predicted gene, 23633
 499
 0.8
chr7_127767459_127768302 0.08 Orai3
 ORAI calcium release-activated calcium modulator 3
 1935
 0.14
chr11_34047188_34048526 0.08 Lcp2
 lymphocyte cytosolic protein 2
 689
 0.72
chr16_54635653_54635804 0.08 Gm23180
 predicted gene, 23180
 7300
 0.29
chr18_56756025_56756589 0.08 Gm15345
 predicted gene 15345
 13410
 0.18
chr16_79109471_79109622 0.08 Tmprss15
 transmembrane protease, serine 15
 18449
 0.28
chr12_86424576_86424958 0.08 Esrrb
 estrogen related receptor, beta
 2884
 0.33
chr2_65848318_65848473 0.08 Csrnp3
 cysteine-serine-rich nuclear protein 3
 2540
 0.31
chr18_32539971_32540198 0.08 Gypc
 glycophorin C
 4666
 0.22
chr10_81497570_81499812 0.08 S1pr4
 sphingosine-1-phosphate receptor 4
 1441
 0.16
chr12_113141740_113143605 0.08 Crip2
 cysteine rich protein 2
 136
 0.92
chr9_121403057_121404479 0.08 Trak1
 trafficking protein, kinesin binding 1
 290
 0.91
chrX_128439905_128440056 0.08 Gm38390
 predicted gene, 38390
 64073
 0.12
chr7_99537223_99537701 0.08 Arrb1
 arrestin, beta 1
 1758
 0.23
chr11_37083444_37083595 0.08 Tenm2
 teneurin transmembrane protein 2
 139353
 0.05
chr6_83171941_83172736 0.08 Gm15624
 predicted gene 15624
 216
 0.83
chr3_88501925_88503550 0.08 Lmna
 lamin A
 570
 0.53
chr1_182281173_182281731 0.08 Degs1
 delta(4)-desaturase, sphingolipid 1
 772
 0.62

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0098828 modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0010612 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.0 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.1 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.0 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0 0.1 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 0.0 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.0 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.0 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.0 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.1 GO:0071280 cellular response to copper ion(GO:0071280)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0070488 neutrophil aggregation(GO:0070488)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.0 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.0 0.0 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.0 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.0 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.0 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0097466 glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0 0.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.0 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.0 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.0 0.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.0 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.0 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0 0.0 GO:2000520 regulation of immunological synapse formation(GO:2000520)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.0 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.0 GO:0006538 glutamate catabolic process(GO:0006538)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.0 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0052714 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:1990190 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.0 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0016937 short-branched-chain-acyl-CoA dehydrogenase activity(GO:0016937)
0.0 0.1 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism