Project

ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nkx2-6

Z-value: 0.67

Motif logo

Transcription factors associated with Nkx2-6

Gene Symbol	Gene ID	Gene Info
Nkx2-6 Ensembl NCBI MGI UniProt	ENSMUSG00000044186.9	Nkx2-6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Nkx2-6	chr14_69169089_69169240	2638	0.170934	0.25	5.4e-02	Click!
Nkx2-6	chr14_69169675_69169826	2052	0.197545	-0.20	1.3e-01	Click!
Nkx2-6	chr14_69171390_69172088	63	0.566269	-0.06	6.5e-01	Click!

Activity of the Nkx2-6 motif across conditions

Conditions sorted by the z-value of the Nkx2-6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_25941347_25942080	1.79	Retreg1	reticulophagy regulator 1	826	0.63
chr10_108434849_108435510	1.69	Gm36283	predicted gene, 36283	1486	0.41
chr8_28593556_28594184	1.68	Gm26795	predicted gene, 26795	338	0.92
chr11_22170917_22171472	1.58	Ehbp1	EH domain binding protein 1	216	0.96
chr1_40805583_40806390	1.54	Tmem182	transmembrane protein 182	385	0.84
chr11_5802324_5803834	1.51	Pgam2	phosphoglycerate mutase 2	654	0.56
chr3_59028229_59029161	1.42	Med12l	mediator complex subunit 12-like	21717	0.13
chr9_111055888_111057545	1.41	Ccrl2	chemokine (C-C motif) receptor-like 2	530	0.62
chr13_46422196_46422985	1.40	Rbm24	RNA binding motif protein 24	768	0.72
chr10_122987387_122988205	1.36	D630033A02Rik	RIKEN cDNA D630033A02 gene	1241	0.4
chr17_69395929_69396464	1.24	Gm49894	predicted gene, 49894	11988	0.14
chr19_34253411_34255499	1.21	Acta2	actin, alpha 2, smooth muscle, aorta	225	0.92
chr3_51708498_51709183	1.21	Gm10729	predicted gene 10729	15069	0.13
chrX_7670339_7671484	1.18	Plp2	proteolipid protein 2	402	0.64
chr6_142701068_142701298	1.18	Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	1035	0.58
chr15_80573378_80573655	1.16	Grap2	GRB2-related adaptor protein 2	922	0.53
chr13_52584896_52585203	1.16	Syk	spleen tyrosine kinase	1546	0.51
chr11_35006795_35007598	1.12	Gm25799	predicted gene, 25799	108179	0.06
chr10_25432250_25432950	1.12	Epb41l2	erythrocyte membrane protein band 4.1 like 2	1	0.98
chr10_13502765_13503111	1.08	Fuca2	fucosidase, alpha-L- 2, plasma	1854	0.34
chr3_98410919_98411390	1.08	Zfp697	zinc finger protein 697	28606	0.12
chr8_111502069_111502570	1.02	Wdr59	WD repeat domain 59	11566	0.17
chr3_60409216_60409437	1.01	Mbnl1	muscleblind like splicing factor 1	63504	0.12
chr3_94933041_94933856	1.01	Selenbp1	selenium binding protein 1	289	0.81
chr19_36732841_36733325	1.01	Ppp1r3c	protein phosphatase 1, regulatory subunit 3C	3570	0.26
chr10_56468695_56469687	1.00	Gm9118	predicted gene 9118	28150	0.16
chr3_144617679_144618017	1.00	Rpl9-ps8	ribosomal protein L9, pseudogene 8	8116	0.15
chr17_72937768_72938085	1.00	Lbh	limb-bud and heart	16738	0.22
chr1_55888894_55889264	1.00	9130227L01Rik	RIKEN cDNA 9130227L01 gene	42162	0.18
chr3_103139237_103140483	0.99	Dennd2c	DENN/MADD domain containing 2C	466	0.74
chr6_113748326_113749056	0.98	Sec13	SEC13 homolog, nuclear pore and COPII coat complex component	7948	0.1
chr9_77637137_77637792	0.98	Klhl31	kelch-like 31	964	0.54
chr6_17761675_17761826	0.96	St7	suppression of tumorigenicity 7	12358	0.15
chr2_69137426_69137980	0.94	Nostrin	nitric oxide synthase trafficker	1903	0.36
chr2_68896037_68896304	0.93	Gm37159	predicted gene, 37159	4804	0.17
chr3_57293411_57293693	0.93	Tm4sf1	transmembrane 4 superfamily member 1	151	0.96
chr3_97075891_97076211	0.93	4930573H18Rik	RIKEN cDNA 4930573H18 gene	16734	0.15
chr9_24642837_24642988	0.91	Cypt4	cysteine-rich perinuclear theca 4	17716	0.21
chr8_89879797_89879982	0.91	Gm24212	predicted gene, 24212	212585	0.02
chr2_91120400_91120551	0.90	Mybpc3	myosin binding protein C, cardiac	2331	0.18
chr4_117928946_117930077	0.89	Artn	artemin	14	0.96
chr9_69458888_69459208	0.88	Mir3109	microRNA 3109	2104	0.2
chr15_76666348_76670076	0.88	Foxh1	forkhead box H1	1590	0.15
chr5_100214650_100214858	0.88	2310034O05Rik	RIKEN cDNA 2310034O05 gene	4046	0.22
chr10_79824203_79824406	0.87	Misp	mitotic spindle positioning	383	0.64
chr6_112459682_112460792	0.87	Cav3	caveolin 3	732	0.65
chr13_41019834_41020226	0.87	Tmem14c	transmembrane protein 14C	3738	0.15
chr11_12308516_12308667	0.86	Gm12002	predicted gene 12002	5923	0.29
chr19_43916774_43917584	0.84	Gm50217	predicted gene, 50217	3294	0.17
chrX_141476575_141476992	0.84	Col4a5	collagen, type IV, alpha 5	1373	0.41
chr17_75435976_75437284	0.84	Rasgrp3	RAS, guanyl releasing protein 3	704	0.77
chr1_150984135_150984286	0.83	Hmcn1	hemicentin 1	8841	0.19
chr5_114146628_114147196	0.80	Acacb	acetyl-Coenzyme A carboxylase beta	377	0.78
chr4_32890178_32890640	0.80	Gm11941	predicted gene 11941	2277	0.29
chr19_6384347_6385874	0.79	Pygm	muscle glycogen phosphorylase	695	0.45
chr1_133492302_133493599	0.79	Gm8596	predicted gene 8596	36529	0.14
chr1_52251127_52251278	0.79	Gls	glutaminase	17970	0.19
chr15_75111128_75111422	0.78	Ly6c2	lymphocyte antigen 6 complex, locus C2	422	0.74
chr10_69571124_69572441	0.78	Gm46231	predicted gene, 46231	5421	0.27
chr5_77126646_77126869	0.77	Gm15831	predicted gene 15831	4409	0.15
chr13_5897408_5897746	0.76	Gm47507	predicted gene, 47507	10468	0.16
chr6_31114239_31115170	0.74	5330406M23Rik	RIKEN cDNA 5330406M23 gene	3784	0.15
chr1_74154525_74154676	0.73	Cxcr2	chemokine (C-X-C motif) receptor 2	609	0.64
chr10_95970803_95971600	0.73	Eea1	early endosome antigen 1	30444	0.15
chr14_79536799_79537268	0.71	Elf1	E74-like factor 1	21335	0.14
chr8_57320946_57324000	0.71	Hand2os1	Hand2, opposite strand 1	1245	0.3
chr5_117133717_117134877	0.70	Taok3	TAO kinase 3	656	0.62
chr10_63366309_63366946	0.70	Gm16145	predicted gene 16145	12774	0.12
chr6_51171741_51172819	0.69	Mir148a	microRNA 148a	97630	0.07
chr15_12323754_12324089	0.69	1810049J17Rik	RIKEN cDNA 1810049J17 gene	2022	0.26
chr19_25383229_25384087	0.69	Kank1	KN motif and ankyrin repeat domains 1	11645	0.21
chr2_119601570_119601760	0.68	Oip5os1	Opa interacting protein 5, opposite strand 1	7362	0.11
chr5_149068416_149068775	0.68	Hmgb1	high mobility group box 1	15082	0.11
chr10_42571122_42571273	0.68	Nr2e1	nuclear receptor subfamily 2, group E, member 1	2369	0.3
chr16_36157136_36157365	0.68	Stfa2l1	stefin A2 like 1	439	0.63
chr10_18886828_18886979	0.67	Gm48483	predicted gene, 48483	126	0.97
chr13_45731554_45731705	0.66	Gm47460	predicted gene, 47460	17943	0.26
chr12_51709478_51709629	0.65	Strn3	striatin, calmodulin binding protein 3	17656	0.16
chr5_67777924_67778180	0.65	Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	1293	0.4
chr11_32280517_32281064	0.64	Hba-a1	hemoglobin alpha, adult chain 1	2721	0.14
chr5_29030494_29030763	0.64	Rnf32	ring finger protein 32	165364	0.03
chr9_113970028_113970753	0.64	Gm47950	predicted gene, 47950	608	0.61
chr12_105034229_105034527	0.64	Glrx5	glutaredoxin 5	838	0.39
chr9_53850550_53850766	0.63	Sln	sarcolipin	494	0.79
chr18_10785293_10785854	0.63	Mir1a-2	microRNA 1a-2	21	0.55
chr8_70803797_70804348	0.63	Mast3	microtubule associated serine/threonine kinase 3	910	0.3
chrX_107149448_107150320	0.61	P2ry10b	purinergic receptor P2Y, G-protein coupled 10B	269	0.92
chrX_136144132_136144311	0.61	Bex4	brain expressed X-linked 4	5225	0.13
chr5_99339481_99340596	0.61	Gm35394	predicted gene, 35394	65943	0.12
chr8_26329826_26330767	0.61	Gm31784	predicted gene, 31784	17962	0.15
chr16_30520227_30520435	0.61	Tmem44	transmembrane protein 44	20578	0.18
chr18_74502159_74502310	0.60	1700120E14Rik	RIKEN cDNA 1700120E14 gene	28872	0.18
chr8_74871836_74872493	0.60	Isx	intestine specific homeobox	1009	0.61
chr9_40877257_40878943	0.60	Bsx	brain specific homeobox	3973	0.16
chr18_65083730_65084940	0.60	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	1281	0.54
chr13_107065067_107065474	0.59	Gm31452	predicted gene, 31452	1575	0.35
chr4_31404597_31405733	0.59	Gm11922	predicted gene 11922	24693	0.28
chr4_45965494_45966277	0.59	Tdrd7	tudor domain containing 7	551	0.79
chr11_49247391_49247809	0.59	Mgat1	mannoside acetylglucosaminyltransferase 1	117	0.94
chr4_115059803_115061295	0.57	Tal1	T cell acute lymphocytic leukemia 1	1041	0.47
chr17_81740807_81741112	0.57	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	2582	0.38
chrX_140540281_140540484	0.56	Tsc22d3	TSC22 domain family, member 3	2286	0.31
chr12_77483355_77483606	0.56	Gm48177	predicted gene, 48177	42918	0.13
chr11_65265838_65266454	0.56	Myocd	myocardin	3708	0.26
chr16_23028396_23028918	0.56	Kng2	kininogen 2	352	0.74
chr5_51923307_51923594	0.56	Gm43175	predicted gene 43175	12519	0.18
chr6_122609501_122610041	0.55	Gdf3	growth differentiation factor 3	53	0.95
chr8_68119212_68120289	0.55	Psd3	pleckstrin and Sec7 domain containing 3	1563	0.51
chr1_164048817_164048989	0.55	Sele	selectin, endothelial cell	669	0.62
chr8_79641995_79642830	0.55	Otud4	OTU domain containing 4	2708	0.24
chr19_55252255_55252406	0.55	Acsl5	acyl-CoA synthetase long-chain family member 5	370	0.85
chr8_94379515_94379666	0.55	Gm15889	predicted gene 15889	1669	0.22
chr8_53637135_53637740	0.54	Neil3	nei like 3 (E. coli)	1241	0.61
chr13_12320716_12320867	0.54	Actn2	actinin alpha 2	19933	0.16
chr12_33061431_33061850	0.53	Cdhr3	cadherin-related family member 3	152	0.89
chr10_7472533_7472784	0.53	Ulbp1	UL16 binding protein 1	683	0.71
chr1_165462988_165463362	0.53	Mpc2	mitochondrial pyruvate carrier 2	1810	0.18
chr6_53986001_53986442	0.53	4921529L05Rik	RIKEN cDNA 4921529L05 gene	7492	0.2
chr1_77213373_77213909	0.53	Gm38265	predicted gene, 38265	66649	0.12
chr2_145822082_145822862	0.52	Rin2	Ras and Rab interactor 2	183	0.96
chr1_50962507_50962885	0.52	Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	35177	0.17
chr14_34273565_34273716	0.52	Shld2	shieldin complex subunit 2	619	0.54
chrX_169688414_169688708	0.52	Mid1	midline 1	3362	0.28
chr8_45681436_45681587	0.52	Sorbs2	sorbin and SH3 domain containing 2	6822	0.23
chr17_88627411_88628033	0.52	Ston1	stonin 1	358	0.85
chr7_24851355_24851650	0.51	Gm18207	predicted gene, 18207	9444	0.09
chr9_75775275_75776608	0.51	Bmp5	bone morphogenetic protein 5	577	0.78
chr1_133799248_133799949	0.51	Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	1438	0.33
chr6_48707462_48707684	0.51	Gimap6	GTPase, IMAP family member 6	623	0.46
chr1_131638462_131638811	0.51	Ctse	cathepsin E	142	0.95
chr1_167269338_167269683	0.51	Uck2	uridine-cytidine kinase 2	15091	0.11
chr2_34944829_34945211	0.50	Traf1	TNF receptor-associated factor 1	13116	0.11
chr4_45489091_45489458	0.50	Shb	src homology 2 domain-containing transforming protein B	129	0.96
chr7_45233983_45235751	0.50	Cd37	CD37 antigen	591	0.44
chr6_87495313_87495551	0.49	Arhgap25	Rho GTPase activating protein 25	882	0.56
chr10_76621571_76623890	0.49	Col6a2	collagen, type VI, alpha 2	595	0.68
chr7_133700764_133701966	0.49	Uros	uroporphyrinogen III synthase	1173	0.35
chr17_70997929_70998765	0.48	Myl12a	myosin, light chain 12A, regulatory, non-sarcomeric	216	0.88
chr13_110882860_110883156	0.48	Gm38397	predicted gene, 38397	20491	0.14
chr14_54711789_54711940	0.48	Cebpe	CCAAT/enhancer binding protein (C/EBP), epsilon	310	0.79
chr10_118858762_118859192	0.48	4932442E05Rik	RIKEN cDNA 4932442E05 gene	1849	0.25
chr11_102145120_102148094	0.48	Nags	N-acetylglutamate synthase	241	0.58
chr7_112268841_112268992	0.47	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	2383	0.41
chr6_119194389_119194967	0.47	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	1553	0.37
chr6_125349409_125350825	0.47	Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	394	0.77
chr10_79988072_79989720	0.47	Cnn2	calponin 2	273	0.76
chr3_101395066_101395306	0.47	Gm42939	predicted gene 42939	12607	0.14
chr2_69672410_69673170	0.47	Klhl41	kelch-like 41	2670	0.21
chr7_98341637_98342055	0.46	Tsku	tsukushi, small leucine rich proteoglycan	18233	0.16
chr12_56695295_56695580	0.46	Pax9	paired box 9	202	0.92
chr14_119285808_119285959	0.46	Gm6087	predicted gene 6087	7459	0.3
chr10_68132791_68133177	0.46	Arid5b	AT rich interactive domain 5B (MRF1-like)	3642	0.31
chr6_33055424_33055891	0.46	Chchd3	coiled-coil-helix-coiled-coil-helix domain containing 3	4560	0.2
chr12_51350200_51351160	0.46	G2e3	G2/M-phase specific E3 ubiquitin ligase	2308	0.33
chr3_51042270_51042900	0.46	Gm29230	predicted gene 29230	32271	0.16
chr4_109664033_109664623	0.46	Cdkn2c	cyclin dependent kinase inhibitor 2C	1044	0.46
chr11_109343750_109344455	0.45	1700096J18Rik	RIKEN cDNA 1700096J18 gene	2737	0.2
chr5_119673827_119675890	0.45	Tbx3	T-box 3	587	0.67
chr16_38709840_38710271	0.45	Arhgap31	Rho GTPase activating protein 31	2843	0.21
chr2_97601844_97601995	0.44	Gm44320	predicted gene, 44320	25133	0.27
chr6_144480846_144480997	0.44	Sox5os2	SRY (sex determining region Y)-box 5, opposite strand 2	304	0.94
chr15_40673370_40673521	0.44	Zfpm2	zinc finger protein, multitype 2	8455	0.3
chr8_40905205_40905856	0.44	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	7092	0.17
chr4_120612414_120612969	0.44	Gm12860	predicted gene 12860	3149	0.19
chr14_54228146_54228679	0.44	Traj1	T cell receptor alpha joining 1	9598	0.08
chr17_47909108_47910390	0.43	Gm15556	predicted gene 15556	12629	0.13
chrX_99045264_99045888	0.42	Stard8	START domain containing 8	1592	0.43
chr5_17887492_17887771	0.42	Cd36	CD36 molecule	1116	0.65
chr1_91052629_91054398	0.42	Lrrfip1	leucine rich repeat (in FLII) interacting protein 1	6	0.98
chr4_46065775_46065926	0.41	Tmod1	tropomodulin 1	11277	0.19
chr6_142878886_142879637	0.41	St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	3779	0.24
chr16_55381050_55381215	0.41	Zpld1	zona pellucida like domain containing 1	83146	0.1
chr10_60828323_60829684	0.41	Unc5b	unc-5 netrin receptor B	2379	0.28
chr4_33379003_33379165	0.41	Rngtt	RNA guanylyltransferase and 5'-phosphatase	48070	0.12
chr14_14067690_14068738	0.40	Atxn7	ataxin 7	19255	0.17
chr3_53165376_53165642	0.40	Gm43803	predicted gene 43803	52098	0.09
chr4_89446020_89446496	0.40	Gm12608	predicted gene 12608	1614	0.4
chr18_39481253_39481404	0.40	Nr3c1	nuclear receptor subfamily 3, group C, member 1	5904	0.28
chr7_128527029_128527321	0.40	Bag3	BCL2-associated athanogene 3	3559	0.15
chr11_96318060_96319501	0.39	Hoxb4	homeobox B4	513	0.51
chr19_45223479_45224523	0.39	Lbx1	ladybird homeobox 1	11811	0.18
chr8_126833216_126834027	0.39	A630001O12Rik	RIKEN cDNA A630001O12 gene	5612	0.23
chr2_92486138_92486303	0.38	Gm13814	predicted gene 13814	2294	0.22
chr17_26841784_26842428	0.38	Nkx2-5	NK2 homeobox 5	541	0.65
chr2_83733967_83734585	0.38	Itgav	integrin alpha V	9721	0.15
chr10_56384887_56385255	0.38	Gja1	gap junction protein, alpha 1	5983	0.21
chr18_23748497_23748648	0.38	Gm15972	predicted gene 15972	3733	0.2
chr5_43981645_43981861	0.38	Fgfbp1	fibroblast growth factor binding protein 1	11	0.96
chr3_27690391_27690623	0.38	Fndc3b	fibronectin type III domain containing 3B	19891	0.25
chr18_50055297_50055988	0.38	C030005K06Rik	RIKEN cDNA C030005K06 gene	1798	0.32
chr16_32610201_32610589	0.38	Tfrc	transferrin receptor	1145	0.41
chr19_25607525_25608179	0.37	Dmrt3	doublesex and mab-3 related transcription factor 3	2449	0.33
chr10_42247495_42248433	0.37	Foxo3	forkhead box O3	10402	0.26
chr1_178798383_178799679	0.37	Kif26b	kinesin family member 26B	593	0.81
chr5_113648616_113649038	0.37	Cmklr1	chemokine-like receptor 1	1569	0.33
chr7_139991869_139992020	0.37	Adam8	a disintegrin and metallopeptidase domain 8	564	0.55
chr12_111421008_111421645	0.37	Exoc3l4	exocyst complex component 3-like 4	235	0.88
chr2_120147858_120148056	0.36	Ehd4	EH-domain containing 4	6505	0.18
chr5_20583581_20583870	0.36	Gm3544	predicted gene 3544	4871	0.26
chr2_148438023_148438174	0.36	Cd93	CD93 antigen	5465	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-6

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.3	0.8	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.2	0.6	GO:0032672	regulation of interleukin-3 production(GO:0032672) granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.2	0.9	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.1	0.5	GO:0003166	bundle of His development(GO:0003166)
0.1	0.6	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1	0.5	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.5	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.1	0.4	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.1	0.4	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.1	0.3	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.4	GO:2000065	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1	0.3	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.1	0.5	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.1	0.6	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.1	0.2	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1	0.4	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1	0.3	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.2	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1	0.2	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.5	GO:2000391	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1	0.2	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.2	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.1	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.2	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1	0.3	GO:0070842	aggresome assembly(GO:0070842)
0.1	0.2	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.1	0.1	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	0.1	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.1	0.5	GO:0044557	relaxation of smooth muscle(GO:0044557)
0.1	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.2	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.1	0.1	GO:0003195	tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
0.1	0.2	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.1	0.3	GO:0031034	myosin filament assembly(GO:0031034)
0.1	0.5	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.3	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.1	0.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.3	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.2	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.2	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	0.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	0.2	GO:1905206	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1	0.3	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	0.2	GO:0061325	cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.1	0.2	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	0.2	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.1	1.2	GO:0014829	vascular smooth muscle contraction(GO:0014829)
0.1	0.6	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.1	0.2	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	0.2	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	1.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.1	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.4	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.6	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.2	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.3	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.8	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.0	0.1	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.5	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0	0.0	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.2	GO:0021764	amygdala development(GO:0021764)
0.0	0.2	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.0	0.4	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0	0.2	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.0	GO:1901671	positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0	0.2	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.2	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.4	GO:0002836	positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.0	GO:0048769	sarcomerogenesis(GO:0048769)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.3	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0035905	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.0	0.1	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.0	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.1	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0003175	tricuspid valve development(GO:0003175)
0.0	0.4	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.5	GO:0044247	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0072672	neutrophil extravasation(GO:0072672)
0.0	0.1	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.3	GO:0051601	exocyst localization(GO:0051601)
0.0	0.0	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.6	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.1	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.4	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.0	GO:0061738	late endosomal microautophagy(GO:0061738)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.0	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0035696	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0	0.0	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.0	0.7	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0	0.1	GO:0015879	carnitine transport(GO:0015879)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.0	GO:0060268	negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.2	GO:0071281	cellular response to iron ion(GO:0071281)
0.0	0.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.0	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.1	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.5	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.1	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.3	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0019661	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.0	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.0	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.1	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.0	0.0	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.0	GO:0060374	mast cell differentiation(GO:0060374)
0.0	0.4	GO:0030225	macrophage differentiation(GO:0030225)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	0.8	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.2	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.0	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.3	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.0	GO:0071335	hair follicle cell proliferation(GO:0071335)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.0	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.0	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.0	0.0	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.0	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.1	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.0	GO:0003192	mitral valve formation(GO:0003192)
0.0	0.0	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269)
0.0	0.0	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.0	0.1	GO:2000020	positive regulation of male gonad development(GO:2000020)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0035989	tendon development(GO:0035989)
0.0	0.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.1	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.0	0.0	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.0	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0	0.0	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.0	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.0	GO:0045794	negative regulation of cell volume(GO:0045794)
0.0	0.0	GO:0061511	centriole elongation(GO:0061511)
0.0	0.0	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.0	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
0.0	0.0	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.3	GO:1900046	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0	0.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.2	GO:0003170	heart valve development(GO:0003170)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0044838	cell quiescence(GO:0044838)
0.0	0.0	GO:0006597	spermine biosynthetic process(GO:0006597)
0.0	0.0	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.0	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.0	GO:0033026	negative regulation of mast cell apoptotic process(GO:0033026)
0.0	0.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0010664	negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0033014	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.1	GO:0001780	neutrophil homeostasis(GO:0001780)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	1.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.2	0.6	GO:0019815	B cell receptor complex(GO:0019815)
0.1	0.3	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.5	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.5	GO:0042629	mast cell granule(GO:0042629)
0.1	0.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.5	GO:0016460	myosin II complex(GO:0016460)
0.0	0.5	GO:0033391	chromatoid body(GO:0033391)
0.0	1.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.6	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	0.2	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.0	GO:1990923	PET complex(GO:1990923)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.6	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.3	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.7	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.0	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.1	GO:0016528	sarcoplasm(GO:0016528)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	1.1	GO:0042383	sarcolemma(GO:0042383)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.0	GO:0090533	sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3	1.1	GO:0042731	PH domain binding(GO:0042731)
0.2	0.4	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.2	0.9	GO:0071253	connexin binding(GO:0071253)
0.2	0.5	GO:0019959	interleukin-8 binding(GO:0019959)
0.2	0.6	GO:0009374	biotin binding(GO:0009374)
0.1	0.4	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.4	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.8	GO:0008430	selenium binding(GO:0008430)
0.1	0.6	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.4	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.2	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.3	GO:0015265	urea channel activity(GO:0015265)
0.1	0.9	GO:0019956	chemokine binding(GO:0019956)
0.1	0.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.3	GO:0034618	arginine binding(GO:0034618)
0.1	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.9	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.4	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.3	GO:0018502	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.1	0.3	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.2	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.4	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.3	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.0	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.0	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.2	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0044682	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	1.0	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0019113	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.4	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.4	GO:0015928	fucosidase activity(GO:0015928)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.5	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.6	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.5	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0005537	mannose binding(GO:0005537)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.0	GO:2001070	starch binding(GO:2001070)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	1.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.8	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.5	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.7	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.5	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.5	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
1.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.7	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.7	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT