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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Nr0b1

Z-value: 0.51

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Transcription factors associated with Nr0b1

Gene Symbol Gene ID Gene Info
Nr0b1
ENSMUSG00000025056.4 nuclear receptor subfamily 0, group B, member 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chrX_86191680_86192868Nr0b15100.8161890.255.5e-02Click!

Activity of the Nr0b1 motif across conditions

Conditions sorted by the z-value of the Nr0b1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_119803355_119804193 0.63 1700021F13Rik
 RIKEN cDNA 1700021F13 gene
 3893
 0.21
chr2_172936311_172937024 0.56 Bmp7
 bone morphogenetic protein 7
 3425
 0.23
chr17_32165675_32166119 0.51 Notch3
 notch 3
 955
 0.45
chr3_9347262_9347787 0.48 C030034L19Rik
 RIKEN cDNA C030034L19 gene
 55540
 0.13
chr6_63256981_63257723 0.46 9330118I20Rik
 RIKEN cDNA 9330118I20 gene
 273
 0.71
chr11_5802324_5803834 0.37 Pgam2
 phosphoglycerate mutase 2
 654
 0.56
chr18_76544225_76544908 0.36 Gm31933
 predicted gene, 31933
 88304
 0.1
chr4_134370897_134371720 0.34 Extl1
 exostosin-like glycosyltransferase 1
 1250
 0.33
chr14_54986330_54986529 0.33 Myh7
 myosin, heavy polypeptide 7, cardiac muscle, beta
 989
 0.26
chr10_78787171_78788340 0.33 Slc1a6
 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
 7053
 0.14
chr16_94721948_94722518 0.33 Gm41505
 predicted gene, 41505
 339
 0.89
chr17_26840808_26841709 0.32 Nkx2-5
 NK2 homeobox 5
 307
 0.83
chr6_29434692_29436459 0.31 Flnc
 filamin C, gamma
 2299
 0.16
chr9_53402629_53402979 0.30 4930550C14Rik
 RIKEN cDNA 4930550C14 gene
 479
 0.73
chr2_167239298_167240893 0.30 Ptgis
 prostaglandin I2 (prostacyclin) synthase
 494
 0.75
chr3_138066011_138066302 0.30 1110002E22Rik
 RIKEN cDNA 1110002E22 gene
 1104
 0.33
chr15_54278043_54279091 0.29 Tnfrsf11b
 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
 83
 0.98
chr14_55826099_55826996 0.29 Nfatc4
 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
 491
 0.63
chr9_21851806_21852608 0.29 Dock6
 dedicator of cytokinesis 6
 409
 0.74
chr8_57324050_57324269 0.29 Hand2os1
 Hand2, opposite strand 1
 74
 0.96
chr10_109921017_109921811 0.28 Nav3
 neuron navigator 3
 17391
 0.27
chr6_54329128_54329297 0.28 9130019P16Rik
 RIKEN cDNA 9130019P16 gene
 1871
 0.29
chr16_4522019_4522667 0.28 Srl
 sarcalumenin
 720
 0.62
chr16_4641802_4643186 0.28 Dnaja3
 DnaJ heat shock protein family (Hsp40) member A3
 2505
 0.16
chr10_22813360_22814229 0.28 Gm10824
 predicted gene 10824
 1955
 0.28
chr13_93612831_93613054 0.28 Gm15622
 predicted gene 15622
 12440
 0.16
chr13_46419789_46420118 0.27 Rbm24
 RNA binding motif protein 24
 139
 0.97
chr7_112225854_112227329 0.27 Mical2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 701
 0.78
chr3_85186481_85187125 0.27 Gm38313
 predicted gene, 38313
 9644
 0.24
chr2_30995683_30996883 0.27 Usp20
 ubiquitin specific peptidase 20
 235
 0.9
chr15_8279541_8279705 0.26 Cplane1
 ciliogenesis and planar polarity effector 1
 32520
 0.18
chr6_82772676_82772834 0.26 Hk2
 hexokinase 2
 233
 0.9
chr1_162219410_162219749 0.26 Dnm3os
 dynamin 3, opposite strand
 289
 0.86
chr3_34795242_34796350 0.26 Gm38509
 predicted gene, 38509
 23721
 0.17
chr7_25787527_25787868 0.26 Axl
 AXL receptor tyrosine kinase
 125
 0.92
chr9_95256675_95257394 0.25 Slc9a9
 solute carrier family 9 (sodium/hydrogen exchanger), member 9
 135348
 0.04
chr4_126627040_126627629 0.25 5730409E04Rik
 RIKEN cDNA 5730409E04Rik gene
 17480
 0.12
chr11_102606785_102607497 0.25 Fzd2
 frizzled class receptor 2
 2745
 0.14
chr1_134036991_134037429 0.25 Fmod
 fibromodulin
 44
 0.97
chr3_138069501_138070764 0.25 1110002E22Rik
 RIKEN cDNA 1110002E22 gene
 1465
 0.3
chr9_77345728_77346390 0.25 Mlip
 muscular LMNA-interacting protein
 1734
 0.32
chr1_69107020_69107405 0.25 Gm16076
 predicted gene 16076
 472
 0.52
chr5_19228089_19228240 0.25 Magi2
 membrane associated guanylate kinase, WW and PDZ domain containing 2
 767
 0.56
chr3_82144651_82145810 0.25 Gucy1a1
 guanylate cyclase 1, soluble, alpha 1
 157
 0.96
chr8_48843313_48843722 0.24 Gm19744
 predicted gene, 19744
 148
 0.81
chr6_53288842_53289356 0.24 Creb5
 cAMP responsive element binding protein 5
 1324
 0.55
chr2_85049344_85049658 0.24 Tnks1bp1
 tankyrase 1 binding protein 1
 959
 0.42
chr2_110361610_110361920 0.24 Fibin
 fin bud initiation factor homolog (zebrafish)
 1418
 0.47
chr13_38153771_38154277 0.23 Gm10129
 predicted gene 10129
 2232
 0.25
chr17_11912724_11913972 0.23 Prkn
 parkin RBR E3 ubiquitin protein ligase
 68138
 0.13
chr3_84189998_84191469 0.23 Trim2
 tripartite motif-containing 2
 210
 0.94
chr19_11818257_11818813 0.23 Stx3
 syntaxin 3
 186
 0.9
chr2_79646122_79646273 0.23 Itprid2
 ITPR interacting domain containing 2
 7015
 0.28
chr19_4439491_4439665 0.23 A930001C03Rik
 RIKEN cDNA A930001C03 gene
 19
 0.64
chr8_81856918_81857264 0.23 Inpp4b
 inositol polyphosphate-4-phosphatase, type II
 723
 0.73
chr7_107665595_107666983 0.22 Ppfibp2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
 978
 0.52
chrX_12116163_12116355 0.22 Bcor
 BCL6 interacting corepressor
 12091
 0.26
chr8_102780577_102781067 0.22 Gm45258
 predicted gene 45258
 220
 0.93
chr13_103355936_103356429 0.22 Gm5454
 predicted gene 5454
 70
 0.97
chr2_31313954_31314959 0.22 Hmcn2
 hemicentin 2
 41
 0.98
chr5_18360537_18360783 0.22 Gnai1
 guanine nucleotide binding protein (G protein), alpha inhibiting 1
 305
 0.93
chr5_132541084_132542037 0.22 Auts2
 autism susceptibility candidate 2
 263
 0.87
chr8_22507762_22508195 0.22 Slc20a2
 solute carrier family 20, member 2
 1752
 0.29
chr14_46389448_46390599 0.22 Bmp4
 bone morphogenetic protein 4
 512
 0.7
chr19_53808045_53808428 0.22 Rbm20
 RNA binding motif protein 20
 14928
 0.16
chr17_42975571_42975917 0.22 Tnfrsf21
 tumor necrosis factor receptor superfamily, member 21
 40811
 0.19
chr6_138171729_138171880 0.22 Mgst1
 microsomal glutathione S-transferase 1
 28950
 0.23
chr13_74362852_74363978 0.22 Lrrc14b
 leucine rich repeat containing 14B
 590
 0.54
chr6_4506970_4507670 0.22 Gm43921
 predicted gene, 43921
 1233
 0.34
chr11_116885438_116886127 0.22 Mfsd11
 major facilitator superfamily domain containing 11
 17414
 0.12
chr7_142472156_142472970 0.22 Lsp1
 lymphocyte specific 1
 412
 0.73
chr2_91120847_91121416 0.22 Mybpc3
 myosin binding protein C, cardiac
 2987
 0.16
chr12_108837523_108838185 0.21 Slc25a47
 solute carrier family 25, member 47
 790
 0.33
chr15_89557488_89558668 0.21 Shank3
 SH3 and multiple ankyrin repeat domains 3
 1376
 0.31
chr5_13280340_13280537 0.21 Sema3a
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 116346
 0.06
chr2_30902329_30903582 0.21 Ptges
 prostaglandin E synthase
 342
 0.83
chr2_163285470_163285918 0.21 Tox2
 TOX high mobility group box family member 2
 34684
 0.16
chr1_134513098_134514080 0.21 Gm15454
 predicted gene 15454
 4492
 0.12
chr10_111419452_111420510 0.21 Nap1l1
 nucleosome assembly protein 1-like 1
 53242
 0.1
chr17_66232919_66233799 0.21 Gm49932
 predicted gene, 49932
 1586
 0.29
chr18_58210827_58211095 0.21 Fbn2
 fibrillin 2
 474
 0.86
chr16_14705845_14706609 0.21 Snai2
 snail family zinc finger 2
 375
 0.9
chr16_35659651_35660734 0.21 Sema5b
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
 757
 0.67
chr17_68002299_68002969 0.21 Arhgap28
 Rho GTPase activating protein 28
 1486
 0.54
chr2_4298620_4299406 0.21 Frmd4a
 FERM domain containing 4A
 1505
 0.32
chr8_120231782_120232001 0.21 Gse1
 genetic suppressor element 1, coiled-coil protein
 3435
 0.2
chr5_125139990_125141281 0.21 Ncor2
 nuclear receptor co-repressor 2
 15735
 0.2
chr2_180332745_180333375 0.21 Gata5os
 GATA binding protein 5, opposite strand
 203
 0.89
chr5_43515484_43516406 0.20 C1qtnf7
 C1q and tumor necrosis factor related protein 7
 183
 0.94
chr9_30921334_30922737 0.20 Adamts15
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
 417
 0.86
chr5_24601266_24602082 0.20 Smarcd3
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
 226
 0.86
chr5_129854658_129854926 0.20 Sumf2
 sulfatase modifying factor 2
 2281
 0.16
chr9_56712934_56713139 0.20 Lingo1
 leucine rich repeat and Ig domain containing 1
 27783
 0.18
chr10_103367601_103367825 0.20 Slc6a15
 solute carrier family 6 (neurotransmitter transporter), member 15
 70
 0.98
chr14_51740214_51741404 0.20 Gm49261
 predicted gene, 49261
 296
 0.81
chr3_128990459_128991248 0.20 Gm9387
 predicted pseudogene 9387
 35755
 0.19
chr5_66746743_66746894 0.20 Limch1
 LIM and calponin homology domains 1
 929
 0.55
chr6_88200114_88201718 0.20 Gata2
 GATA binding protein 2
 3
 0.96
chr7_24499513_24500150 0.20 Cadm4
 cell adhesion molecule 4
 130
 0.91
chr19_34253411_34255499 0.20 Acta2
 actin, alpha 2, smooth muscle, aorta
 225
 0.92
chr13_32966469_32966620 0.20 Serpinb6b
 serine (or cysteine) peptidase inhibitor, clade B, member 6b
 1041
 0.43
chr2_30469737_30470841 0.20 Ier5l
 immediate early response 5-like
 3930
 0.16
chr4_155839735_155840422 0.20 Mxra8os
 matrix-remodelling associated 8, opposite strand
 100
 0.67
chr2_67565793_67566876 0.19 B3galt1
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
 463
 0.84
chr10_22158248_22159850 0.19 H60b
 histocompatibility 60b
 463
 0.42
chr7_30291325_30291668 0.19 Clip3
 CAP-GLY domain containing linker protein 3
 232
 0.8
chr7_112180336_112180681 0.19 Dkk3
 dickkopf WNT signaling pathway inhibitor 3
 21451
 0.22
chr10_67939481_67939695 0.19 Zfp365
 zinc finger protein 365
 26926
 0.16
chr14_105893244_105894185 0.19 Spry2
 sprouty RTK signaling antagonist 2
 3105
 0.29
chr16_30540363_30541394 0.19 Tmem44
 transmembrane protein 44
 31
 0.98
chr11_105293049_105293533 0.19 Mrc2
 mannose receptor, C type 2
 623
 0.74
chr4_31823845_31825033 0.19 Map3k7
 mitogen-activated protein kinase kinase kinase 7
 139658
 0.05
chr4_34436178_34436537 0.19 Gm12351
 predicted gene 12351
 21533
 0.16
chr1_74090075_74091356 0.19 Tns1
 tensin 1
 636
 0.71
chr7_18957439_18958650 0.19 Nanos2
 nanos C2HC-type zinc finger 2
 29356
 0.06
chr15_76194294_76195998 0.19 Plec
 plectin
 564
 0.56
chr4_42950234_42951162 0.19 Dnajb5
 DnaJ heat shock protein family (Hsp40) member B5
 258
 0.87
chr6_128285700_128286493 0.19 Gm21893
 predicted gene, 21893
 8006
 0.09
chr1_134801190_134801791 0.18 Gm37949
 predicted gene, 37949
 495
 0.7
chr1_135793443_135794350 0.18 Tnni1
 troponin I, skeletal, slow 1
 5506
 0.15
chr4_11705100_11705674 0.18 Gem
 GTP binding protein (gene overexpressed in skeletal muscle)
 420
 0.85
chr12_71229100_71229280 0.18 Gm19045
 predicted gene, 19045
 23746
 0.15
chr15_3581853_3582700 0.18 Ghr
 growth hormone receptor
 320
 0.92
chr7_16581555_16581911 0.18 Gm29443
 predicted gene 29443
 32091
 0.08
chr5_103426807_103426958 0.18 Ptpn13
 protein tyrosine phosphatase, non-receptor type 13
 1381
 0.47
chr12_113185913_113186788 0.18 Tmem121
 transmembrane protein 121
 420
 0.74
chr3_87172043_87172207 0.18 Kirrel
 kirre like nephrin family adhesion molecule 1
 2425
 0.26
chr3_82073600_82074661 0.18 Gucy1b1
 guanylate cyclase 1, soluble, beta 1
 543
 0.77
chr18_35034038_35034310 0.18 Gm36037
 predicted gene, 36037
 51204
 0.09
chr17_46444584_46445824 0.18 Gm5093
 predicted gene 5093
 5107
 0.11
chr11_72406421_72408105 0.18 Smtnl2
 smoothelin-like 2
 4155
 0.15
chr15_61770777_61771058 0.18 D030024E09Rik
 RIKEN cDNA D030024E09 gene
 3534
 0.33
chr7_3367594_3368044 0.18 Gm44257
 predicted gene, 44257
 22261
 0.07
chr10_66901546_66901931 0.18 Gm47903
 predicted gene, 47903
 10126
 0.15
chr2_113217092_113217461 0.18 Ryr3
 ryanodine receptor 3
 180
 0.96
chrX_99044012_99044163 0.18 Stard8
 START domain containing 8
 103
 0.97
chr9_119982824_119983895 0.18 1700019L13Rik
 RIKEN cDNA 1700019L13 gene
 80
 0.79
chr17_71782384_71783600 0.18 Clip4
 CAP-GLY domain containing linker protein family, member 4
 375
 0.84
chr6_47044703_47045103 0.18 Cntnap2
 contactin associated protein-like 2
 157
 0.64
chr5_134746440_134747928 0.18 Eln
 elastin
 62
 0.61
chr9_64014385_64014870 0.18 Smad6
 SMAD family member 6
 2360
 0.24
chr7_101394207_101396000 0.18 Arap1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
 448
 0.73
chr4_97776884_97777081 0.17 Nfia
 nuclear factor I/A
 626
 0.6
chr3_141491675_141491844 0.17 Unc5c
 unc-5 netrin receptor C
 26088
 0.21
chr2_167542817_167543436 0.17 Snai1
 snail family zinc finger 1
 4931
 0.13
chr9_48986724_48987891 0.17 Usp28
 ubiquitin specific peptidase 28
 1842
 0.32
chr1_128592817_128593419 0.17 Cxcr4
 chemokine (C-X-C motif) receptor 4
 825
 0.66
chr6_118479444_118479781 0.17 Zfp9
 zinc finger protein 9
 292
 0.88
chr5_124529436_124529809 0.17 Gm43034
 predicted gene 43034
 1511
 0.21
chr8_110805706_110805934 0.17 Il34
 interleukin 34
 52
 0.67
chr18_37172243_37172684 0.17 Gm38097
 predicted gene, 38097
 101
 0.95
chr9_71591283_71592381 0.17 Myzap
 myocardial zonula adherens protein
 433
 0.84
chr11_105292145_105293042 0.17 Mrc2
 mannose receptor, C type 2
 50
 0.98
chr10_76583951_76585206 0.17 Ftcd
 formiminotransferase cyclodeaminase
 2555
 0.18
chr11_114479225_114479452 0.17 4932435O22Rik
 RIKEN cDNA 4932435O22 gene
 30478
 0.2
chr13_48662866_48663051 0.17 Barx1
 BarH-like homeobox 1
 40
 0.97
chr11_70232254_70232932 0.17 Mir497
 microRNA 497
 2124
 0.1
chr2_74681727_74681878 0.17 Hoxd11
 homeobox D11
 521
 0.45
chr14_51738531_51739887 0.17 Gm49261
 predicted gene, 49261
 1896
 0.19
chr9_89497628_89497779 0.17 Gm47403
 predicted gene, 47403
 62681
 0.11
chr4_48407474_48407947 0.17 Invs
 inversin
 25522
 0.19
chr7_126248023_126249285 0.17 Sbk1
 SH3-binding kinase 1
 208
 0.69
chr15_42962907_42963107 0.17 Rspo2
 R-spondin 2
 207811
 0.02
chr13_31810556_31811961 0.17 Foxc1
 forkhead box C1
 4625
 0.19
chr17_26847878_26848155 0.17 Nkx2-5
 NK2 homeobox 5
 3007
 0.15
chr6_94281635_94282188 0.17 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 1114
 0.58
chr1_193508615_193509882 0.17 Mir205hg
 Mir205 host gene
 926
 0.47
chr6_112273463_112275203 0.16 Lmcd1
 LIM and cysteine-rich domains 1
 575
 0.71
chr2_94263215_94263820 0.16 Mir670hg
 MIR670 host gene (non-protein coding)
 1091
 0.4
chr7_100924536_100925334 0.16 Arhgef17
 Rho guanine nucleotide exchange factor (GEF) 17
 7172
 0.15
chr13_3709021_3709715 0.16 Gm47695
 predicted gene, 47695
 50457
 0.09
chr10_75174015_75174616 0.16 Bcr
 BCR activator of RhoGEF and GTPase
 350
 0.89
chr2_71367675_71367887 0.16 Slc25a12
 solute carrier family 25 (mitochondrial carrier, Aralar), member 12
 32
 0.97
chr1_12691898_12692734 0.16 Sulf1
 sulfatase 1
 7
 0.98
chr16_16217315_16217547 0.16 Pkp2
 plakophilin 2
 4113
 0.23
chr2_35557994_35559313 0.16 Gm13446
 predicted gene 13446
 49
 0.85
chr2_35621752_35623107 0.16 Dab2ip
 disabled 2 interacting protein
 269
 0.93
chr7_104314930_104315471 0.16 Trim12a
 tripartite motif-containing 12A
 143
 0.53
chr10_68282341_68283288 0.16 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 4074
 0.25
chr19_47313387_47314780 0.16 Sh3pxd2a
 SH3 and PX domains 2A
 668
 0.69
chr7_104352827_104353391 0.16 Trim12c
 tripartite motif-containing 12C
 229
 0.84
chr6_114918735_114919212 0.16 Vgll4
 vestigial like family member 4
 2843
 0.31
chr7_45215829_45217292 0.16 Tead2
 TEA domain family member 2
 113
 0.88
chr17_26451915_26452093 0.16 Gm50269
 predicted gene, 50269
 12153
 0.13
chr15_85670939_85672357 0.16 Lncppara
 long noncoding RNA near Ppara
 18032
 0.13
chr11_103096614_103097909 0.16 Plcd3
 phospholipase C, delta 3
 4330
 0.13
chr9_77917044_77917252 0.16 Elovl5
 ELOVL family member 5, elongation of long chain fatty acids (yeast)
 216
 0.92
chr7_4520460_4522358 0.16 Tnni3
 troponin I, cardiac 3
 842
 0.35
chr6_14902200_14902426 0.16 Foxp2
 forkhead box P2
 835
 0.77
chr10_62338281_62338607 0.16 Hk1os
 hexokinase 1, opposite strand
 1812
 0.27
chr2_153224755_153225797 0.16 Tspyl3
 TSPY-like 3
 165
 0.93
chr5_142819565_142820054 0.16 Tnrc18
 trinucleotide repeat containing 18
 2147
 0.28
chr5_91402281_91403314 0.16 Btc
 betacellulin, epidermal growth factor family member
 25
 0.99
chr11_85833878_85836704 0.15 Tbx2
 T-box 2
 2740
 0.17
chr4_148001445_148002010 0.15 Nppa
 natriuretic peptide type A
 1005
 0.33
chr4_152096248_152097724 0.15 Plekhg5
 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
 267
 0.86
chr1_135788611_135788952 0.15 Tnni1
 troponin I, skeletal, slow 1
 5716
 0.15
chr5_103693169_103693605 0.15 Aff1
 AF4/FMR2 family, member 1
 1013
 0.5
chr7_75141792_75142655 0.15 Sv2b
 synaptic vesicle glycoprotein 2 b
 5503
 0.3
chr7_19747051_19747276 0.15 Nectin2
 nectin cell adhesion molecule 2
 2370
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr0b1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.5 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.2 GO:0035993 deltoid tuberosity development(GO:0035993)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.4 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.1 0.3 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.2 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.3 GO:2000618 regulation of histone H4-K16 acetylation(GO:2000618)
0.1 0.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.1 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.0 0.2 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.2 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.0 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.0 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 0.1 GO:1903261 regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.2 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.0 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.3 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.0 0.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.0 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.0 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.1 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.0 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.2 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0060509 Type I pneumocyte differentiation(GO:0060509)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.0 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.1 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.1 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.0 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.0 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0021747 cochlear nucleus development(GO:0021747)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.0 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.0 0.0 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.0 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.1 GO:0060973 cell migration involved in heart development(GO:0060973)
0.0 0.1 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.0 GO:0046909 intermembrane transport(GO:0046909)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.0 0.0 GO:1904528 regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0 0.0 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.0 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.0 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.0 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.0 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.0 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.0 GO:0042525 tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.3 GO:1990462 omegasome(GO:1990462)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.3 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0018638 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.4 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 ST ADRENERGIC Adrenergic Pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha