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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Nr2c1

Z-value: 0.59

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Transcription factors associated with Nr2c1

Gene Symbol	Gene ID	Gene Info
Nr2c1 Ensembl NCBI MGI UniProt	ENSMUSG00000005897.8	nuclear receptor subfamily 2, group C, member 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_94149504_94150012	Nr2c1	1339	0.351064	-0.28	2.9e-02	Click!
chr10_94148808_94148959	Nr2c1	464	0.755356	-0.08	5.4e-01	Click!
chr10_94150806_94150977	Nr2c1	2472	0.212914	-0.08	5.6e-01	Click!
chr10_94147624_94148712	Nr2c1	145	0.941655	0.04	7.5e-01	Click!
chr10_94165488_94165639	Nr2c1	9277	0.140757	0.04	7.7e-01	Click!

Activity of the Nr2c1 motif across conditions

Conditions sorted by the z-value of the Nr2c1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_144547334_144548656	1.40	Nptx2	neuronal pentraxin 2	2093	0.41
chr9_120021605_120021794	1.18	Xirp1	xin actin-binding repeat containing 1	1884	0.19
chr18_76855816_76857376	1.16	Skor2	SKI family transcriptional corepressor 2	191	0.96
chr7_78575006_78575482	1.14	Gm39038	predicted gene, 39038	12	0.97
chrX_170674573_170675954	1.11	Asmt	acetylserotonin O-methyltransferase	2619	0.41
chr9_87739615_87740838	1.10	Gm37374	predicted gene, 37374	206	0.93
chr2_83758891_83759726	0.99	Gm13684	predicted gene 13684	557	0.73
chr5_34182980_34183403	0.92	Mxd4	Max dimerization protein 4	1179	0.3
chr11_55604950_55605292	0.91	Glra1	glycine receptor, alpha 1 subunit	2612	0.3
chr10_41070697_41071486	0.90	Gpr6	G protein-coupled receptor 6	1194	0.41
chr13_53469792_53470715	0.88	Msx2	msh homeobox 2	2821	0.27
chr17_43954528_43954986	0.86	Rcan2	regulator of calcineurin 2	1506	0.53
chr5_113490881_113491656	0.85	Wscd2	WSC domain containing 2	516	0.83
chr6_82091782_82092469	0.82	Gm15864	predicted gene 15864	39544	0.14
chr4_153481347_153482221	0.82	Ajap1	adherens junction associated protein 1	395	0.92
chr4_141010412_141011785	0.81	Mfap2	microfibrillar-associated protein 2	454	0.71
chr14_122459815_122460898	0.80	Zic5	zinc finger protein of the cerebellum 5	335	0.81
chr1_194622071_194623282	0.80	Plxna2	plexin A2	2851	0.26
chr9_121299469_121300553	0.79	Trak1	trafficking protein, kinesin binding 1	2182	0.23
chr5_24334809_24334960	0.78	Gm15589	predicted gene 15589	961	0.39
chr9_41376046_41377501	0.76	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	212	0.93
chr1_95662771_95663208	0.76	St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	4546	0.23
chr8_108406602_108407498	0.76	Gm39244	predicted gene, 39244	129897	0.05
chr18_31443497_31444446	0.73	Syt4	synaptotagmin IV	3435	0.19
chr7_99272446_99273539	0.72	Map6	microtubule-associated protein 6	3860	0.15
chr10_79806462_79808470	0.71	Palm	paralemmin	785	0.35
chr10_81021201_81021561	0.69	Gm16099	predicted gene 16099	3430	0.11
chr7_46097493_46097815	0.68	Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	772	0.46
chr14_25586887_25588082	0.67	Zmiz1	zinc finger, MIZ-type containing 1	19873	0.17
chr15_89532557_89533956	0.67	Shank3	SH3 and multiple ankyrin repeat domains 3	366	0.78
chr15_73839069_73840200	0.66	Mroh5	maestro heat-like repeat family member 5	37	0.97
chr15_103026302_103028215	0.65	Hoxc4	homeobox C4	7137	0.09
chr5_142811476_142811629	0.64	Tnrc18	trinucleotide repeat containing 18	5828	0.19
chr2_158375202_158376961	0.64	Snhg11	small nucleolar RNA host gene 11	319	0.74
chr17_35505957_35506108	0.64	Pou5f1	POU domain, class 5, transcription factor 1	14	0.93
chr8_125897868_125898882	0.63	Pcnx2	pecanex homolog 2	58	0.88
chr8_47284401_47285223	0.63	Stox2	storkhead box 2	4550	0.27
chr16_6841576_6842071	0.63	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	32601	0.26
chr7_49914124_49915124	0.61	Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	2924	0.34
chr9_124441736_124442440	0.61	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	658	0.65
chr7_128205575_128206445	0.61	Cox6a2	cytochrome c oxidase subunit 6A2	377	0.67
chr18_36939256_36940257	0.60	Pcdha2	protocadherin alpha 2	532	0.46
chr3_152980951_152982389	0.60	St6galnac5	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	382	0.86
chr11_59138017_59138780	0.59	Obscn	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	772	0.52
chr4_151127830_151127981	0.59	Camta1	calmodulin binding transcription activator 1	1590	0.42
chr2_158609356_158610186	0.59	Gm14204	predicted gene 14204	819	0.36
chr8_12947702_12949640	0.59	Mcf2l	mcf.2 transforming sequence-like	718	0.37
chr7_105785466_105785617	0.58	Dchs1	dachsous cadherin related 1	2011	0.18
chr8_62952744_62952895	0.58	Spock3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3	894	0.63
chr7_27957807_27957958	0.58	Gm10651	predicted pseudogene 10651	8119	0.11
chr8_22508392_22509319	0.58	Slc20a2	solute carrier family 20, member 2	2629	0.22
chr9_124439879_124441093	0.58	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	382	0.83
chr13_64035278_64035429	0.57	Hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	27780	0.16
chr9_110051810_110053856	0.57	Map4	microtubule-associated protein 4	781	0.54
chr3_88210226_88210408	0.56	Gm3764	predicted gene 3764	845	0.35
chr9_91352783_91353195	0.56	A730094K22Rik	RIKEN cDNA A730094K22 gene	2036	0.19
chrX_110811626_110812334	0.56	Gm44593	predicted gene 44593	344	0.89
chr15_31296980_31298102	0.55	Ankrd33b	ankyrin repeat domain 33B	10653	0.14
chr11_9118055_9119445	0.54	Upp1	uridine phosphorylase 1	37	0.98
chr13_94876260_94878233	0.54	Otp	orthopedia homeobox	1644	0.4
chr8_123894797_123895120	0.54	Acta1	actin, alpha 1, skeletal muscle	207	0.85
chr11_3504903_3505132	0.54	Inpp5j	inositol polyphosphate 5-phosphatase J	196	0.87
chr2_26339437_26339737	0.53	Gpsm1	G-protein signalling modulator 1 (AGS3-like, C. elegans)	139	0.91
chr9_117837070_117837361	0.53	Rbms3	RNA binding motif, single stranded interacting protein	35369	0.18
chr12_106080982_106081684	0.53	Gm46378	predicted gene, 46378	3037	0.25
chr14_24616899_24617392	0.52	4930542C16Rik	RIKEN cDNA 4930542C16 gene	159	0.78
chr16_31943940_31944452	0.52	Pigz	phosphatidylinositol glycan anchor biosynthesis, class Z	2283	0.13
chr17_55970296_55971683	0.52	Shd	src homology 2 domain-containing transforming protein D	400	0.68
chr10_80009830_80009981	0.51	Arhgap45	Rho GTPase activating protein 45	6748	0.07
chr2_32605823_32605974	0.51	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	1063	0.28
chr13_83715222_83716973	0.51	C130071C03Rik	RIKEN cDNA C130071C03 gene	5284	0.15
chr5_115431565_115432258	0.51	Msi1	musashi RNA-binding protein 1	1306	0.22
chr3_17798321_17798878	0.51	Mir124-2hg	Mir124-2 host gene (non-protein coding)	2855	0.23
chr1_134339239_134339390	0.50	Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	6386	0.13
chr6_52965291_52965504	0.50	Gm26215	predicted gene, 26215	45135	0.14
chr7_79504311_79505700	0.50	Mir9-3	microRNA 9-3	259	0.82
chr2_170734259_170734932	0.50	Dok5	docking protein 5	2788	0.35
chr12_118852808_118853969	0.50	Sp8	trans-acting transcription factor 8	5802	0.24
chr6_83404978_83405260	0.49	Mir6374	microRNA 6374	4017	0.14
chr12_76081146_76082447	0.49	Syne2	spectrin repeat containing, nuclear envelope 2	140	0.97
chr10_76344505_76344665	0.49	Dip2a	disco interacting protein 2 homolog A	647	0.64
chr3_105706804_105707390	0.48	Inka2	inka box actin regulator 2	1639	0.26
chr2_26634084_26634235	0.48	Dipk1b	divergent protein kinase domain 1B	44	0.94
chr5_23429149_23429300	0.48	5031425E22Rik	RIKEN cDNA 5031425E22 gene	4085	0.16
chr5_102100207_102100695	0.48	Gm29707	predicted gene, 29707	29601	0.14
chr1_172018523_172018674	0.47	Vangl2	VANGL planar cell polarity 2	8113	0.14
chr17_45920036_45920187	0.47	Gm41584	predicted gene, 41584	34765	0.12
chr12_105453821_105454975	0.47	D430019H16Rik	RIKEN cDNA D430019H16 gene	542	0.76
chr7_79498955_79500626	0.47	Mir9-3hg	Mir9-3 host gene	236	0.84
chr2_136713069_136714459	0.47	Snap25	synaptosomal-associated protein 25	286	0.92
chr2_113327774_113328199	0.46	Fmn1	formin 1	204	0.94
chr5_134101487_134102203	0.46	Castor2	cytosolic arginine sensor for mTORC1 subunit 2	1840	0.26
chr4_154945869_154946537	0.46	Hes5	hes family bHLH transcription factor 5	14720	0.11
chr17_8429499_8430158	0.46	T	brachyury, T-box transcription factor T	4595	0.19
chr5_112520948_112521383	0.45	Sez6l	seizure related 6 homolog like	46038	0.1
chr13_34133417_34134151	0.45	Gm36500	predicted gene, 36500	76	0.95
chr1_132316080_132316995	0.45	Nuak2	NUAK family, SNF1-like kinase, 2	372	0.79
chr16_77417791_77418279	0.45	Gm38071	predicted gene, 38071	1411	0.28
chr7_25068107_25069005	0.45	Grik5	glutamate receptor, ionotropic, kainate 5 (gamma 2)	3363	0.14
chr4_22478508_22478806	0.45	Pou3f2	POU domain, class 3, transcription factor 2	9709	0.17
chr2_163206219_163206674	0.45	Tox2	TOX high mobility group box family member 2	1893	0.35
chr12_12693706_12694681	0.44	Gm25538	predicted gene, 25538	5846	0.17
chr8_23132120_23132667	0.44	Gm15815	predicted gene 15815	4937	0.11
chr2_167537717_167538031	0.44	Snai1	snail family zinc finger 1	321	0.81
chr7_139086002_139087206	0.44	Dpysl4	dihydropyrimidinase-like 4	576	0.74
chr2_30097085_30097294	0.44	Zdhhc12	zinc finger, DHHC domain containing 12	3541	0.12
chr2_6883618_6884699	0.44	Gm13389	predicted gene 13389	112	0.85
chrX_99137870_99138145	0.44	Efnb1	ephrin B1	124	0.97
chr13_99513069_99513554	0.43	Map1b	microtubule-associated protein 1B	3207	0.2
chr18_79071481_79071862	0.43	Setbp1	SET binding protein 1	37720	0.22
chr1_159524626_159524870	0.43	Tnr	tenascin R	907	0.65
chr3_89763591_89764832	0.43	Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	397	0.76
chr8_87037668_87038705	0.43	Rps13-ps1	ribosomal protein S13, pseudogene 1	9503	0.17
chr5_136238361_136238512	0.43	Sh2b2	SH2B adaptor protein 2	6401	0.14
chr16_60602088_60602266	0.43	Gm9017	predicted gene 9017	2589	0.24
chr11_5802324_5803834	0.43	Pgam2	phosphoglycerate mutase 2	654	0.56
chr7_44973695_44975193	0.43	Cpt1c	carnitine palmitoyltransferase 1c	331	0.61
chr3_95696412_95696933	0.43	Adamtsl4	ADAMTS-like 4	8755	0.1
chr13_64315557_64315911	0.42	Prxl2c	peroxiredoxin like 2C	3024	0.13
chr5_24982764_24982915	0.42	1500035N22Rik	RIKEN cDNA 1500035N22 gene	3003	0.24
chr7_78575992_78576673	0.42	Gm39038	predicted gene, 39038	1100	0.39
chr5_134238122_134238273	0.42	Gtf2i	general transcription factor II I	2848	0.18
chr18_37663804_37664034	0.41	Gm37118	predicted gene, 37118	1287	0.14
chr8_120575933_120576084	0.41	Gse1	genetic suppressor element 1, coiled-coil protein	4679	0.11
chr18_59062200_59063436	0.41	Minar2	membrane integral NOTCH2 associated receptor 2	307	0.94
chr18_67511489_67511640	0.41	Spire1	spire type actin nucleation factor 1	5830	0.18
chr5_111424407_111425623	0.41	Gm43119	predicted gene 43119	1426	0.38
chr5_110545528_110545748	0.41	Galnt9	polypeptide N-acetylgalactosaminyltransferase 9	1283	0.39
chr11_120020575_120020893	0.40	Aatk	apoptosis-associated tyrosine kinase	566	0.59
chr18_84074730_84075170	0.40	Tshz1	teashirt zinc finger family member 1	10125	0.16
chr8_95354616_95354905	0.40	Mmp15	matrix metallopeptidase 15	2492	0.19
chr13_81944263_81944829	0.40	F830210D05Rik	RIKEN cDNA F830210D05 gene	14859	0.26
chr1_194621653_194621902	0.40	Plxna2	plexin A2	1952	0.34
chr12_8495918_8496727	0.40	Rhob	ras homolog family member B	3687	0.18
chr4_135174988_135175978	0.39	Runx3	runt related transcription factor 3	21047	0.15
chr3_156564902_156565177	0.39	Negr1	neuronal growth regulator 1	2889	0.27
chr6_48537635_48538183	0.39	Atp6v0e2	ATPase, H+ transporting, lysosomal V0 subunit E2	244	0.61
chr8_71685721_71686960	0.38	Insl3	insulin-like 3	2874	0.12
chr10_13982681_13983672	0.38	Hivep2	human immunodeficiency virus type I enhancer binding protein 2	16152	0.19
chr3_84217272_84217435	0.38	Trim2	tripartite motif-containing 2	3492	0.28
chr5_118929922_118930545	0.38	Gm43342	predicted gene 43342	2110	0.32
chr10_80177626_80177980	0.38	Efna2	ephrin A2	1679	0.18
chr12_111353800_111353990	0.38	Cdc42bpb	CDC42 binding protein kinase beta	23724	0.13
chr4_33716448_33717151	0.38	Gm24341	predicted gene, 24341	35308	0.2
chr9_57696029_57697476	0.38	Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	861	0.48
chr2_168447547_168447953	0.38	Gm14234	predicted gene 14234	29176	0.19
chr11_55601469_55602112	0.38	Glra1	glycine receptor, alpha 1 subunit	5943	0.22
chr19_4758474_4759201	0.38	Rbm4b	RNA binding motif protein 4B	1932	0.18
chr11_102394791_102396113	0.38	Rundc3a	RUN domain containing 3A	2049	0.17
chr13_72298974_72299125	0.37	Gm4052	predicted gene 4052	51172	0.15
chr1_89457566_89457902	0.37	Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	2478	0.29
chr1_135374257_135375340	0.37	Shisa4	shisa family member 4	279	0.86
chr3_96424839_96424993	0.37	Gm24136	predicted gene, 24136	2183	0.1
chr15_103038687_103039944	0.37	Hoxc4	homeobox C4	4920	0.1
chr4_126464266_126464731	0.37	Ago1	argonaute RISC catalytic subunit 1	2716	0.17
chr7_45304558_45305606	0.37	Trpm4	transient receptor potential cation channel, subfamily M, member 4	122	0.9
chr12_106474400_106475045	0.37	Gm3191	predicted gene 3191	15572	0.17
chr3_3507690_3508493	0.37	Hnf4g	hepatocyte nuclear factor 4, gamma	61	0.98
chr17_12762808_12762986	0.37	Igf2r	insulin-like growth factor 2 receptor	6767	0.13
chr3_105962812_105962963	0.37	Wdr77	WD repeat domain 77	1265	0.24
chr1_69790500_69791180	0.36	Gm37930	predicted gene, 37930	19972	0.21
chr5_132394811_132395242	0.36	Gm42989	predicted gene 42989	22345	0.15
chr4_149075794_149076058	0.35	Gm9506	predicted gene 9506	20457	0.12
chr1_172218328_172218648	0.35	Casq1	calsequestrin 1	1227	0.28
chr2_119268931_119270073	0.35	Rhov	ras homolog family member V	1770	0.21
chr19_53793336_53793637	0.35	Rbm20	RNA binding motif protein 20	178	0.94
chr10_8761475_8762950	0.35	Sash1	SAM and SH3 domain containing 1	262	0.93
chr9_32835753_32835904	0.35	Gm37167	predicted gene, 37167	4094	0.24
chr12_55438453_55439133	0.35	Psma6	proteasome subunit alpha 6	31410	0.13
chr2_49619321_49620607	0.35	Kif5c	kinesin family member 5C	666	0.78
chr6_136167149_136168437	0.34	Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	4096	0.25
chr17_35140108_35141075	0.34	Bag6	BCL2-associated athanogene 6	360	0.57
chr11_98360332_98361761	0.34	Stard3	START domain containing 3	2602	0.12
chr11_3910058_3910209	0.34	Slc35e4	solute carrier family 35, member E4	4531	0.11
chr1_66467636_66468234	0.34	Unc80	unc-80, NALCN activator	432	0.85
chr9_72665710_72665959	0.34	Nedd4	neural precursor cell expressed, developmentally down-regulated 4	2835	0.14
chr6_5725575_5726689	0.34	Dync1i1	dynein cytoplasmic 1 intermediate chain 1	314	0.94
chr11_117436519_117437340	0.34	Gm11732	predicted gene 11732	10751	0.14
chr10_128381063_128381470	0.34	Mir6914	microRNA 6914	1572	0.14
chrX_105390628_105392456	0.33	5330434G04Rik	RIKEN cDNA 5330434G04 gene	212	0.93
chr3_109286535_109286686	0.33	Vav3	vav 3 oncogene	54043	0.14
chr3_34656299_34657721	0.33	Sox2ot	SOX2 overlapping transcript (non-protein coding)	974	0.4
chr2_29046202_29046836	0.33	Cfap77	cilia and flagella associated protein 77	7159	0.17
chr9_108824114_108825614	0.33	Gm35025	predicted gene, 35025	3	0.87
chr17_37002443_37003493	0.33	Zfp57	zinc finger protein 57	70	0.93
chr5_117068973_117069842	0.33	Gm7478	predicted gene 7478	10595	0.17
chr2_163392737_163392895	0.33	Jph2	junctophilin 2	5133	0.15
chr7_65157281_65157432	0.33	Fam189a1	family with sequence similarity 189, member A1	786	0.63
chr17_80148180_80148718	0.33	Galm	galactose mutarotase	3297	0.21
chr8_125349587_125349941	0.33	Gm16237	predicted gene 16237	122441	0.05
chr13_48155311_48155462	0.32	Gm36346	predicted gene, 36346	81865	0.08
chr11_101471331_101471482	0.32	Rnd2	Rho family GTPase 2	3231	0.09
chrX_41404646_41404797	0.32	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)	1981	0.42
chr4_82510609_82512039	0.32	Gm11266	predicted gene 11266	3308	0.25
chr19_4440980_4441188	0.32	A930001C03Rik	RIKEN cDNA A930001C03 gene	1525	0.24
chr8_87838025_87838279	0.32	Zfp423	zinc finger protein 423	33713	0.22
chr19_16873202_16873655	0.32	Foxb2	forkhead box B2	377	0.85
chr7_34569925_34571186	0.32	Gm12784	predicted gene 12784	23349	0.15
chr12_71048832_71049275	0.32	Arid4a	AT rich interactive domain 4A (RBP1-like)	712	0.65
chr8_71377836_71378740	0.32	Nr2f6	nuclear receptor subfamily 2, group F, member 6	2498	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2c1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0003130	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.2	0.5	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.2	0.8	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.1	0.4	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.4	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1	0.6	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.1	0.4	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.1	0.3	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.1	0.3	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	0.3	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.3	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.1	0.3	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1	0.3	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1	1.1	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
0.1	0.2	GO:2001055	positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1	0.3	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.5	GO:0099515	actin filament-based transport(GO:0099515)
0.1	0.4	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1	0.3	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.1	0.7	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.2	GO:0006533	aspartate catabolic process(GO:0006533)
0.1	0.2	GO:0061642	chemoattraction of axon(GO:0061642)
0.1	0.2	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.2	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.1	0.2	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.5	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.1	0.2	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1	0.4	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1	0.2	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.1	0.4	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.1	0.4	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1	0.3	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.1	0.6	GO:0007614	short-term memory(GO:0007614)
0.1	0.1	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.2	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.3	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.2	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.2	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
0.0	0.3	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.2	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.2	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.2	GO:0061590	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0051582	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0	0.5	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.1	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.3	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.6	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	0.1	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.2	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.2	GO:0051013	microtubule severing(GO:0051013)
0.0	0.3	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.0	0.1	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.2	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.1	GO:2000821	regulation of grooming behavior(GO:2000821)
0.0	0.2	GO:0014028	notochord formation(GO:0014028)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0030035	microspike assembly(GO:0030035)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.3	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0045794	negative regulation of cell volume(GO:0045794)
0.0	0.2	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.2	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.2	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.3	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.3	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.5	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.1	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.2	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.1	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.0	0.1	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.2	GO:0015816	glycine transport(GO:0015816)
0.0	0.3	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.0	0.1	GO:0030421	defecation(GO:0030421)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.2	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.0	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.3	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:0050975	sensory perception of touch(GO:0050975)
0.0	0.0	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0052151	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.0	0.1	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0	0.2	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.1	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	0.3	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.0	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0003284	septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.0	GO:0003190	atrioventricular valve formation(GO:0003190)
0.0	0.0	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.2	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.0	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.3	GO:0030220	platelet formation(GO:0030220)
0.0	0.1	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.0	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0	0.0	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0098828	modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.2	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.0	GO:0009180	purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0	0.0	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.0	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.0	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.8	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0	0.0	GO:1902659	pharyngeal arch artery morphogenesis(GO:0061626) regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.1	GO:0006868	glutamine transport(GO:0006868)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0003175	tricuspid valve development(GO:0003175)
0.0	0.0	GO:0061198	fungiform papilla formation(GO:0061198)
0.0	0.1	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.0	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0009068	aspartate family amino acid catabolic process(GO:0009068)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.0	GO:1903365	regulation of fear response(GO:1903365) positive regulation of fear response(GO:1903367) regulation of behavioral fear response(GO:2000822) positive regulation of behavioral fear response(GO:2000987)
0.0	0.0	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.0	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.1	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.3	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.0	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.9	GO:0008306	associative learning(GO:0008306)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0070640	vitamin D3 metabolic process(GO:0070640)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0	0.2	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.1	GO:0060770	regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.0	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	0.1	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.0	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.2	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	0.0	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0	0.0	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.3	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.0	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0	0.0	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.0	GO:1900238	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.2	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.2	GO:0043153	photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.1	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.0	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0036344	platelet morphogenesis(GO:0036344)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.1	GO:0006337	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.4	GO:0009395	phospholipid catabolic process(GO:0009395)
0.0	0.1	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.0	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.0	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.0	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.2	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.0	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	0.0	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0	0.0	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.1	GO:1903817	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.1	GO:0042428	serotonin metabolic process(GO:0042428)
0.0	0.0	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.0	0.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.1	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.1	GO:0001771	immunological synapse formation(GO:0001771)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0072534	perineuronal net(GO:0072534)
0.1	0.3	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.4	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.2	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.2	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	0.2	GO:0030478	actin cap(GO:0030478)
0.0	0.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.2	GO:0071817	MMXD complex(GO:0071817)
0.0	0.8	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.7	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.4	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.1	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.1	GO:0044393	microspike(GO:0044393)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.0	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.3	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.0	0.2	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.0	GO:0000811	GINS complex(GO:0000811)
0.0	0.0	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.0	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.4	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:1990716	axonemal central apparatus(GO:1990716)
0.0	0.5	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.2	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0016460	myosin II complex(GO:0016460)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0071565	nBAF complex(GO:0071565)
0.0	0.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0031941	filamentous actin(GO:0031941)
0.0	0.4	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.0	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.0	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.0	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.3	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.0	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0032281	AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.2	0.5	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2	0.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.7	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.6	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.3	GO:0045503	dynein light chain binding(GO:0045503)
0.1	0.2	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.3	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.1	0.3	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.1	GO:0051373	FATZ binding(GO:0051373)
0.1	0.2	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1	0.3	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.1	0.2	GO:0070573	metallodipeptidase activity(GO:0070573)
0.1	0.6	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.8	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	0.4	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.5	GO:0031432	titin binding(GO:0031432)
0.1	0.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.2	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.3	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.2	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.5	GO:0031005	filamin binding(GO:0031005)
0.0	0.2	GO:0031433	telethonin binding(GO:0031433)
0.0	0.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.3	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.0	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.0	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.7	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.3	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.3	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0004083	bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.4	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.1	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0015922	aspartate oxidase activity(GO:0015922)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.4	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.3	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.4	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.2	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	1.2	GO:0046332	SMAD binding(GO:0046332)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.3	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.0	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.0	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.0	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.0	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.0	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.0	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.0	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.3	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.4	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly

Results for Nr2c1

Z-value: 0.59

Motif logo

Transcription factors associated with Nr2c1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nr2c1 motif across conditions

Conditions sorted by the z-value of the Nr2c1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2c1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: