Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Nr3c2

Z-value: 0.75

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Transcription factors associated with Nr3c2

Gene Symbol Gene ID Gene Info
Nr3c2
ENSMUSG00000031618.7 nuclear receptor subfamily 3, group C, member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr8_77132765_77133214Nr3c249760.2321460.512.9e-05Click!
chr8_77044923_77045251Nr3c2829260.0889380.411.3e-03Click!
chr8_76902707_76902893Nr3c23240.8823970.392.0e-03Click!
chr8_76912612_76912763Nr3c244150.2457490.339.5e-03Click!
chr8_76901608_76902608Nr3c21800.933412-0.238.2e-02Click!

Activity of the Nr3c2 motif across conditions

Conditions sorted by the z-value of the Nr3c2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_101448217_101448875 4.30 Ifi35
 interferon-induced protein 35
 24
 0.92
chr5_143625482_143626083 3.48 Cyth3
 cytohesin 3
 3248
 0.24
chr16_38374654_38375717 2.81 Popdc2
 popeye domain containing 2
 3187
 0.17
chrX_13469647_13469909 2.70 Nyx
 nyctalopin
 3668
 0.23
chr6_34862829_34863673 2.66 Tmem140
 transmembrane protein 140
 11
 0.96
chr2_158141899_158142209 2.46 Tgm2
 transglutaminase 2, C polypeptide
 2318
 0.24
chr18_12257613_12257833 2.16 Ankrd29
 ankyrin repeat domain 29
 13974
 0.14
chr12_12488453_12488685 2.11 4921511I17Rik
 RIKEN cDNA 4921511I17 gene
 95954
 0.08
chr11_115899671_115901427 2.10 Smim5
 small integral membrane protein 5
 347
 0.75
chr10_43518568_43518757 2.10 Gm47889
 predicted gene, 47889
 91
 0.95
chr10_117281690_117282226 2.08 Lyz2
 lysozyme 2
 363
 0.81
chr8_94178564_94180490 2.06 Mt1
 metallothionein 1
 286
 0.81
chr4_115828937_115829088 2.05 Mob3c
 MOB kinase activator 3C
 354
 0.81
chr12_103630582_103631271 1.96 Serpina10
 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
 495
 0.69
chr6_90624636_90625023 1.95 Slc41a3
 solute carrier family 41, member 3
 5682
 0.15
chr13_112046443_112047142 1.92 Gm15323
 predicted gene 15323
 41290
 0.14
chr15_5243498_5243891 1.86 Ptger4
 prostaglandin E receptor 4 (subtype EP4)
 478
 0.75
chr15_36715797_36716780 1.81 Gm49263
 predicted gene, 49263
 7359
 0.15
chr4_155468952_155469786 1.74 Tmem52
 transmembrane protein 52
 222
 0.87
chr11_102437215_102438375 1.74 Fam171a2
 family with sequence similarity 171, member A2
 1982
 0.17
chr16_36934847_36935880 1.73 Hcls1
 hematopoietic cell specific Lyn substrate 1
 380
 0.77
chr7_97748212_97748509 1.70 Aqp11
 aquaporin 11
 10071
 0.16
chr11_90686079_90686230 1.70 Tom1l1
 target of myb1-like 1 (chicken)
 1425
 0.46
chr1_165717936_165719081 1.68 Gm37073
 predicted gene, 37073
 3048
 0.14
chr12_76709422_76710754 1.66 Sptb
 spectrin beta, erythrocytic
 65
 0.98
chr1_87650650_87651222 1.64 Inpp5d
 inositol polyphosphate-5-phosphatase D
 25303
 0.15
chr2_167671877_167672567 1.62 Gm14320
 predicted gene 14320
 10113
 0.1
chr15_102102083_102102892 1.61 Tns2
 tensin 2
 259
 0.86
chr16_21826993_21827376 1.60 Map3k13
 mitogen-activated protein kinase kinase kinase 13
 1242
 0.33
chr4_154024404_154026596 1.55 Smim1
 small integral membrane protein 1
 116
 0.93
chr19_53194082_53195694 1.50 Add3
 adducin 3 (gamma)
 65
 0.97
chr17_27056910_27058117 1.47 Itpr3
 inositol 1,4,5-triphosphate receptor 3
 209
 0.87
chr11_69096707_69097996 1.47 Per1
 period circadian clock 1
 1597
 0.16
chr14_46536264_46536434 1.45 Gm48912
 predicted gene, 48912
 19907
 0.11
chr2_181079821_181080027 1.44 Kcnq2
 potassium voltage-gated channel, subfamily Q, member 2
 15497
 0.13
chr8_71406049_71406500 1.41 Ankle1
 ankyrin repeat and LEM domain containing 1
 250
 0.83
chr11_34845636_34846358 1.40 Gm22022
 predicted gene, 22022
 3643
 0.22
chr18_54436599_54436760 1.40 Redrum
 Redrum, erythroid developmental long intergenic non-protein coding transcript
 14384
 0.22
chr1_191956577_191957080 1.36 Rd3
 retinal degeneration 3
 20542
 0.11
chr16_34922552_34923302 1.30 Mylk
 myosin, light polypeptide kinase
 7415
 0.19
chr3_51661793_51662907 1.29 Mgst2
 microsomal glutathione S-transferase 2
 1125
 0.38
chr9_22136067_22136415 1.27 Acp5
 acid phosphatase 5, tartrate resistant
 530
 0.54
chr8_111295256_111295437 1.27 Rfwd3
 ring finger and WD repeat domain 3
 4845
 0.16
chr2_174159770_174159921 1.27 Gm10714
 predicted gene 10714
 24073
 0.16
chr10_70127596_70128163 1.26 Ccdc6
 coiled-coil domain containing 6
 30758
 0.2
chr17_27018044_27018864 1.26 Ggnbp1
 gametogenetin binding protein 1
 392
 0.71
chr10_128743161_128743519 1.24 Dgka
 diacylglycerol kinase, alpha
 735
 0.43
chr12_40016524_40017443 1.24 Arl4a
 ADP-ribosylation factor-like 4A
 2499
 0.29
chr3_145591307_145591663 1.23 Znhit6
 zinc finger, HIT type 6
 4383
 0.23
chr11_69915606_69917001 1.22 Gps2
 G protein pathway suppressor 2
 262
 0.72
chr5_112288747_112288992 1.21 Tpst2
 protein-tyrosine sulfotransferase 2
 107
 0.94
chr4_104913144_104913947 1.21 Fyb2
 FYN binding protein 2
 21
 0.98
chr9_32342355_32342506 1.18 Kcnj5
 potassium inwardly-rectifying channel, subfamily J, member 5
 1807
 0.31
chr3_52029454_52030701 1.17 Gm37465
 predicted gene, 37465
 26052
 0.1
chr7_80995833_80996208 1.16 Gm44967
 predicted gene 44967
 1337
 0.26
chr7_78914724_78915335 1.12 Isg20
 interferon-stimulated protein
 700
 0.57
chr15_6081136_6081368 1.10 Gm8047
 predicted gene 8047
 46291
 0.16
chr19_5306588_5308182 1.09 Gm42064
 predicted gene, 42064
 31
 0.93
chr3_89570102_89570404 1.09 Kcnn3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
 50089
 0.1
chr1_75144472_75144783 1.08 Retreg2
 reticulophagy regulator family member 2
 677
 0.43
chr17_47507886_47508650 1.08 Ccnd3
 cyclin D3
 3027
 0.19
chr16_15889582_15890122 1.08 Cebpd
 CCAAT/enhancer binding protein (C/EBP), delta
 1436
 0.42
chr1_172510177_172510457 1.07 Gm37125
 predicted gene, 37125
 2932
 0.14
chr8_121904943_121905414 1.07 Slc7a5
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
 2516
 0.15
chr13_51846753_51848355 1.06 Gadd45g
 growth arrest and DNA-damage-inducible 45 gamma
 810
 0.69
chr8_105831399_105831715 1.05 Tsnaxip1
 translin-associated factor X (Tsnax) interacting protein 1
 3805
 0.1
chr5_66079108_66079628 1.04 Rbm47
 RNA binding motif protein 47
 1616
 0.27
chr4_40849281_40849945 1.04 Mir5123
 microRNA 5123
 525
 0.38
chr1_181255916_181257436 1.04 Rpl35a-ps2
 ribosomal protein L35A, pseudogene 2
 14356
 0.14
chr19_5559639_5561263 1.03 1810058N15Rik
 RIKEN cDNA 1810058N15 gene
 191
 0.47
chr11_44510011_44510178 1.01 Rnf145
 ring finger protein 145
 8870
 0.17
chr2_30716357_30717429 0.99 Gm14488
 predicted gene 14488
 150
 0.94
chr14_48133184_48133904 0.99 Gm49310
 predicted gene, 49310
 680
 0.61
chr13_108670846_108671019 0.98 Rps3a3
 ribosomal protein S3A3
 329
 0.92
chr17_45599296_45600146 0.97 Slc29a1
 solute carrier family 29 (nucleoside transporters), member 1
 115
 0.92
chr9_21352648_21353105 0.96 Slc44a2
 solute carrier family 44, member 2
 4513
 0.11
chr5_118480209_118480360 0.95 Gm15754
 predicted gene 15754
 6683
 0.21
chr13_52986026_52986367 0.94 Nfil3
 nuclear factor, interleukin 3, regulated
 5123
 0.19
chr14_76149541_76149852 0.93 Nufip1
 nuclear fragile X mental retardation protein interacting protein 1
 38805
 0.15
chr3_84475488_84475639 0.93 Fhdc1
 FH2 domain containing 1
 3419
 0.29
chr11_64839925_64840124 0.92 Gm12292
 predicted gene 12292
 3729
 0.32
chr12_117744512_117744705 0.92 Rapgef5
 Rap guanine nucleotide exchange factor (GEF) 5
 4013
 0.25
chr12_110975345_110976350 0.92 Ankrd9
 ankyrin repeat domain 9
 2408
 0.19
chr17_56756624_56758021 0.91 Nrtn
 neurturin
 208
 0.88
chr2_104498055_104498315 0.91 Hipk3
 homeodomain interacting protein kinase 3
 3739
 0.19
chr8_116501999_116502150 0.90 Dynlrb2
 dynein light chain roadblock-type 2
 2900
 0.32
chr15_83606896_83607158 0.90 Scube1
 signal peptide, CUB domain, EGF-like 1
 6712
 0.15
chr13_75707504_75708793 0.89 Ell2
 elongation factor RNA polymerase II 2
 437
 0.65
chr11_72429181_72429515 0.88 Ggt6
 gamma-glutamyltransferase 6
 6178
 0.13
chr16_15948263_15948760 0.86 Cebpd
 CCAAT/enhancer binding protein (C/EBP), delta
 60095
 0.1
chr17_26509441_26509592 0.85 Dusp1
 dual specificity phosphatase 1
 997
 0.39
chr4_59196198_59196829 0.81 Ugcg
 UDP-glucose ceramide glucosyltransferase
 6955
 0.18
chr4_89524955_89525174 0.81 Gm12608
 predicted gene 12608
 80420
 0.09
chr7_128296590_128296741 0.80 BC017158
 cDNA sequence BC017158
 911
 0.38
chr7_127800319_127801635 0.79 Hsd3b7
 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
 36
 0.92
chr13_99100172_99101285 0.79 Gm807
 predicted gene 807
 22
 0.98
chr4_24216144_24216295 0.78 Gm11892
 predicted gene 11892
 21881
 0.28
chr6_34862527_34862817 0.78 Tmem140
 transmembrane protein 140
 474
 0.7
chr12_73507259_73507518 0.78 Gm34016
 predicted gene, 34016
 1282
 0.42
chr18_54907818_54907969 0.78 Zfp608
 zinc finger protein 608
 12331
 0.2
chr11_85799424_85800600 0.77 Bcas3
 breast carcinoma amplified sequence 3
 1809
 0.24
chr19_9978713_9979183 0.76 Fth1
 ferritin heavy polypeptide 1
 1650
 0.22
chr1_154117439_154118596 0.76 A830008E24Rik
 RIKEN cDNA A830008E24 gene
 66
 0.97
chr1_174171241_174171450 0.75 Spta1
 spectrin alpha, erythrocytic 1
 1431
 0.24
chr11_95104821_95105967 0.75 Dlx3
 distal-less homeobox 3
 14725
 0.12
chr12_58265531_58265740 0.74 Clec14a
 C-type lectin domain family 14, member a
 3655
 0.34
chr15_82406468_82407080 0.74 Gm27331
 predicted gene, 27331
 379
 0.39
chr4_40781630_40781889 0.74 Psenen-ps
 presenilin enhancer gamma secretase subunit, pseudogene
 6195
 0.14
chr5_33216392_33216677 0.74 Spon2
 spondin 2, extracellular matrix protein
 574
 0.72
chr18_10839643_10840307 0.73 Gm18764
 predicted gene, 18764
 19705
 0.14
chr7_80994626_80994777 0.72 Gm44967
 predicted gene 44967
 18
 0.93
chr4_133007332_133008511 0.72 Ahdc1
 AT hook, DNA binding motif, containing 1
 3339
 0.22
chr17_5091693_5091844 0.71 Gm15599
 predicted gene 15599
 20342
 0.23
chr13_37346508_37346993 0.71 Ly86
 lymphocyte antigen 86
 1361
 0.39
chr10_85128093_85128664 0.70 Mterf2
 mitochondrial transcription termination factor 2
 351
 0.86
chr6_31124166_31124436 0.70 5330406M23Rik
 RIKEN cDNA 5330406M23 gene
 13381
 0.11
chr3_87900872_87901055 0.70 Hdgf
 heparin binding growth factor
 5358
 0.11
chr17_40806812_40807076 0.69 Crisp2
 cysteine-rich secretory protein 2
 59
 0.97
chr2_34565012_34565383 0.69 Gm13408
 predicted gene 13408
 198
 0.95
chr10_81359308_81359697 0.69 Mfsd12
 major facilitator superfamily domain containing 12
 1950
 0.11
chr16_49839981_49840391 0.67 Cd47
 CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
 15180
 0.25
chr11_32296600_32297646 0.67 Hba-a2
 hemoglobin alpha, adult chain 2
 495
 0.66
chr5_123397462_123398184 0.67 Gm15747
 predicted gene 15747
 134
 0.82
chr7_45126094_45126702 0.67 Snord35a
 small nucleolar RNA, C/D box 35A
 37
 0.47
chr3_87767082_87768667 0.66 Pear1
 platelet endothelial aggregation receptor 1
 1061
 0.43
chr11_32283784_32284776 0.65 Hba-a1
 hemoglobin alpha, adult chain 1
 469
 0.66
chr14_88123382_88123800 0.65 Rps3a2
 ribosomal protein S3A2
 217
 0.93
chr2_4560599_4561970 0.65 Frmd4a
 FERM domain containing 4A
 1509
 0.43
chr1_181838056_181838455 0.65 Gm26004
 predicted gene, 26004
 2313
 0.2
chr11_84872602_84872983 0.63 Ggnbp2
 gametogenetin binding protein 2
 1975
 0.2
chr2_170148791_170149171 0.62 Zfp217
 zinc finger protein 217
 878
 0.72
chr10_77440841_77441276 0.62 Gm35920
 predicted gene, 35920
 16859
 0.15
chr19_8714838_8715424 0.61 Slc3a2
 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
 698
 0.32
chr1_164405360_164405594 0.61 Gm37411
 predicted gene, 37411
 19236
 0.14
chr7_71711939_71712090 0.61 Gm17988
 predicted gene, 17988
 5823
 0.18
chr5_125392659_125393102 0.60 Ubc
 ubiquitin C
 2678
 0.17
chrX_162727288_162727912 0.60 Gm15201
 predicted gene 15201
 9013
 0.14
chr2_143889252_143889441 0.60 Gm11686
 predicted gene 11686
 8169
 0.14
chr18_84412019_84412170 0.60 Zfp407
 zinc finger protein 407
 326
 0.92
chr14_65805868_65806583 0.60 Pbk
 PDZ binding kinase
 7
 0.98
chr15_12375225_12376436 0.59 Pdzd2
 PDZ domain containing 2
 36550
 0.14
chr1_33645834_33645985 0.59 Gm17813
 predicted gene, 17813
 11872
 0.13
chr11_32245145_32245675 0.59 Nprl3
 nitrogen permease regulator-like 3
 4768
 0.12
chr2_38997767_38998606 0.58 Gm13496
 predicted gene 13496
 72
 0.57
chr10_19186197_19186616 0.58 Gm20139
 predicted gene, 20139
 19168
 0.18
chr15_82378536_82379272 0.58 Cyp2d22
 cytochrome P450, family 2, subfamily d, polypeptide 22
 1339
 0.18
chr6_82770788_82771321 0.57 Hk2
 hexokinase 2
 1934
 0.25
chr18_34362164_34362756 0.57 Reep5
 receptor accessory protein 5
 10037
 0.17
chr11_49764573_49765151 0.57 Gm23813
 predicted gene, 23813
 6971
 0.14
chr9_53609339_53609759 0.57 Acat1
 acetyl-Coenzyme A acetyltransferase 1
 781
 0.57
chr5_92933209_92933495 0.57 Shroom3
 shroom family member 3
 5285
 0.23
chr17_47332265_47332516 0.56 Mrps10
 mitochondrial ribosomal protein S10
 36497
 0.1
chr6_38835149_38835559 0.56 Hipk2
 homeodomain interacting protein kinase 2
 1870
 0.4
chr12_78205797_78206679 0.56 Gm6657
 predicted gene 6657
 5272
 0.17
chr6_91116004_91117353 0.56 Nup210
 nucleoporin 210
 118
 0.95
chr2_25577192_25580600 0.55 Ajm1
 apical junction component 1
 1001
 0.25
chr16_38370407_38370971 0.55 Popdc2
 popeye domain containing 2
 1263
 0.34
chr6_146501386_146502829 0.54 Itpr2
 inositol 1,4,5-triphosphate receptor 2
 71
 0.97
chr9_66305145_66305804 0.54 Dapk2
 death-associated protein kinase 2
 37100
 0.14
chr5_134314919_134315630 0.54 Gtf2i
 general transcription factor II I
 514
 0.7
chr7_28865529_28866495 0.54 Lgals7
 lectin, galactose binding, soluble 7
 1557
 0.2
chrX_154974620_154974827 0.54 Gm6645
 predicted gene 6645
 2
 0.96
chr5_149643277_149643428 0.54 Gm20005
 predicted gene, 20005
 1742
 0.28
chr6_134928964_134929556 0.54 Lockd
 lncRNA downstream of Cdkn1b
 105
 0.9
chr8_109613033_109613184 0.53 Pkd1l3
 polycystic kidney disease 1 like 3
 1409
 0.33
chr2_158166874_158167121 0.53 Tgm2
 transglutaminase 2, C polypeptide
 20561
 0.13
chr3_146407041_146407816 0.53 Ssx2ip
 synovial sarcoma, X 2 interacting protein
 2450
 0.2
chr9_106198580_106199667 0.52 Ppm1m
 protein phosphatase 1M
 17
 0.95
chr17_29093963_29095348 0.52 1700023B13Rik
 RIKEN cDNA 1700023B13 gene
 194
 0.82
chr5_137290070_137291279 0.52 Ache
 acetylcholinesterase
 1427
 0.17
chr2_39008141_39008933 0.52 Arpc5l
 actin related protein 2/3 complex, subunit 5-like
 380
 0.72
chr14_25377750_25379085 0.52 Gm26660
 predicted gene, 26660
 218
 0.94
chr5_31697163_31697872 0.51 Rbks
 ribokinase
 110
 0.58
chr2_119333754_119334576 0.51 Dll4
 delta like canonical Notch ligand 4
 5627
 0.13
chr11_59960539_59961087 0.51 Rasd1
 RAS, dexamethasone-induced 1
 4131
 0.14
chr4_130173825_130175545 0.50 Tinagl1
 tubulointerstitial nephritis antigen-like 1
 6
 0.97
chr4_106798811_106800382 0.50 Acot11
 acyl-CoA thioesterase 11
 194
 0.93
chr12_44270345_44270549 0.50 Pnpla8
 patatin-like phospholipase domain containing 8
 1280
 0.31
chr2_128700549_128700956 0.50 Mertk
 MER proto-oncogene tyrosine kinase
 1796
 0.3
chr4_154926533_154926891 0.50 Tnfrsf14
 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
 1365
 0.31
chr5_129730231_129730850 0.49 Gm15903
 predicted gene 15903
 2368
 0.17
chr3_148958783_148960002 0.48 Adgrl2
 adhesion G protein-coupled receptor L2
 4605
 0.24
chr16_58498366_58498517 0.48 St3gal6
 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
 900
 0.59
chr9_32940723_32941376 0.48 Gm27162
 predicted gene 27162
 12083
 0.21
chr2_70425556_70425707 0.48 Rpl9-ps7
 ribosomal protein L9, pseudogene 7
 33351
 0.14
chr19_57361091_57362043 0.47 Fam160b1
 family with sequence similarity 160, member B1
 537
 0.55
chr8_94035053_94035555 0.47 Nudt21
 nudix (nucleoside diphosphate linked moiety X)-type motif 21
 1702
 0.22
chr4_63557098_63557688 0.47 Tmem268
 transmembrane protein 268
 1388
 0.3
chr12_47139542_47139693 0.47 Gm36971
 predicted gene, 36971
 25425
 0.24
chr15_77931320_77931782 0.47 Txn2
 thioredoxin 2
 2545
 0.21
chr17_35896363_35897367 0.46 Gm16279
 predicted gene 16279
 81
 0.64
chr19_15941445_15941936 0.46 Gm3329
 predicted gene 3329
 1920
 0.31
chr16_96192359_96192600 0.46 Lca5l
 Leber congenital amaurosis 5-like
 208
 0.92
chr5_31048714_31049304 0.45 Slc5a6
 solute carrier family 5 (sodium-dependent vitamin transporter), member 6
 85
 0.68
chr8_84203803_84204350 0.45 Gm37352
 predicted gene, 37352
 3207
 0.07
chr14_30921218_30921369 0.45 Itih3
 inter-alpha trypsin inhibitor, heavy chain 3
 2256
 0.18
chr17_57248057_57248976 0.45 Gpr108
 G protein-coupled receptor 108
 70
 0.92
chr5_113945581_113945982 0.45 Gm42797
 predicted gene 42797
 15647
 0.11
chr14_101872557_101872708 0.44 Lmo7
 LIM domain only 7
 3162
 0.35
chr7_25385870_25386460 0.44 Lipe
 lipase, hormone sensitive
 1239
 0.23

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr3c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.5 1.8 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.4 1.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.2 0.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 0.6 GO:0060931 sinoatrial node cell development(GO:0060931)
0.2 1.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.2 0.6 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.2 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.4 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.1 1.3 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.1 0.4 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.4 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.9 GO:0015858 nucleoside transport(GO:0015858)
0.1 0.2 GO:0032672 regulation of interleukin-3 production(GO:0032672)
0.1 0.6 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.8 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.1 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1 0.3 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0071462 cellular response to water stimulus(GO:0071462)
0.1 0.3 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.8 GO:0019835 cytolysis(GO:0019835)
0.1 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:0008228 opsonization(GO:0008228)
0.1 0.5 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.2 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.1 0.2 GO:0002432 granuloma formation(GO:0002432)
0.1 0.2 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.7 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 0.1 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 1.8 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 1.0 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 1.0 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.5 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0016553 adenosine to inosine editing(GO:0006382) base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.0 0.6 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0 0.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0 0.3 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0060068 vagina development(GO:0060068)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.0 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.0 GO:0060264 regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0 0.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0097286 iron ion import(GO:0097286)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.0 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.0 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.2 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.0 GO:0090156 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.8 GO:0021675 nerve development(GO:0021675)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.0 GO:1903147 negative regulation of mitophagy(GO:1903147)
0.0 0.0 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.0 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.0 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0030825 positive regulation of cGMP metabolic process(GO:0030825)
0.0 0.0 GO:0010535 positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0002192 IRES-dependent translational initiation(GO:0002192) IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.0 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.3 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.0 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0008091 spectrin(GO:0008091)
0.3 1.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0005712 chiasma(GO:0005712)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.0 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 1.0 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 1.7 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0015265 urea channel activity(GO:0015265)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.3 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 1.5 GO:0030487 inositol-4,5-bisphosphate 5-phosphatase activity(GO:0030487)
0.1 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0034843 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0 2.0 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 2.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.2 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0016662 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0018572 2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.0 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 1.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 4.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis