Project

ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nr4a2

Z-value: 0.67

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Transcription factors associated with Nr4a2

Gene Symbol	Gene ID	Gene Info
Nr4a2 Ensembl NCBI MGI UniProt	ENSMUSG00000026826.7	Nr4a2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Nr4a2	chr2_57108369_57108639	4568	0.231462	-0.33	1.0e-02	Click!
Nr4a2	chr2_57108036_57108294	4907	0.227124	-0.32	1.3e-02	Click!
Nr4a2	chr2_57103499_57104216	9215	0.204004	0.27	4.0e-02	Click!
Nr4a2	chr2_57113017_57113298	85	0.974064	-0.24	6.0e-02	Click!
Nr4a2	chr2_57121724_57121895	2194	0.317606	0.24	6.1e-02	Click!

Activity of the Nr4a2 motif across conditions

Conditions sorted by the z-value of the Nr4a2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_32137776_32137927	2.22	Fosl2	fos-like antigen 2	1678	0.31
chr10_71158552_71158735	1.72	Bicc1	BicC family RNA binding protein 1	1047	0.39
chr11_90032262_90032532	1.70	Tmem100	transmembrane protein 100	2049	0.38
chr11_65266805_65267363	1.69	Myocd	myocardin	2770	0.29
chr3_133233594_133234317	1.48	Arhgef38	Rho guanine nucleotide exchange factor (GEF) 38	934	0.64
chr11_5802324_5803834	1.44	Pgam2	phosphoglycerate mutase 2	654	0.56
chr4_120813489_120813640	1.42	Nfyc	nuclear transcription factor-Y gamma	2148	0.21
chr3_5089996_5090891	1.27	Gm17308	predicted gene, 17308	167	0.97
chr12_35532487_35532918	1.26	Gm48236	predicted gene, 48236	1719	0.29
chr3_24609075_24609226	1.19	Gm24704	predicted gene, 24704	47076	0.2
chr13_12337560_12337849	1.10	Actn2	actinin alpha 2	3020	0.23
chr14_68581840_68582088	1.09	Adamdec1	ADAM-like, decysin 1	131	0.97
chr6_10612444_10612595	1.07	Gm2691	predicted gene 2691	162495	0.04
chr1_134802830_134803774	1.06	Ppp1r12b	protein phosphatase 1, regulatory subunit 12B	549	0.61
chr1_151347755_151347925	1.05	Gm10138	predicted gene 10138	2609	0.2
chr4_132655459_132655610	1.04	Eya3	EYA transcriptional coactivator and phosphatase 3	1166	0.45
chr6_125322165_125322764	1.02	Scnn1a	sodium channel, nonvoltage-gated 1 alpha	943	0.39
chr18_76200378_76201192	0.99	Gm9028	predicted gene 9028	23398	0.15
chr10_58396489_58397099	0.95	Lims1	LIM and senescent cell antigen-like domains 1	2406	0.3
chr4_140665169_140665889	0.92	Arhgef10l	Rho guanine nucleotide exchange factor (GEF) 10-like	483	0.74
chr6_34601698_34602422	0.91	Cald1	caldesmon 1	3440	0.25
chr4_123235360_123236060	0.90	Heyl	hairy/enhancer-of-split related with YRPW motif-like	1857	0.21
chr3_151762523_151763341	0.89	Ifi44l	interferon-induced protein 44 like	40	0.98
chr1_66861267_66861452	0.89	Acadl	acyl-Coenzyme A dehydrogenase, long-chain	1918	0.18
chr2_76805529_76805788	0.86	Ttn	titin	20884	0.22
chr8_57530953_57531157	0.86	Galnt7	polypeptide N-acetylgalactosaminyltransferase 7	7398	0.1
chr10_121263429_121264335	0.86	Gm35404	predicted gene, 35404	20880	0.14
chr6_37097381_37097532	0.86	Dgki	diacylglycerol kinase, iota	32946	0.23
chrX_117306580_117306731	0.85	Gm14918	predicted gene 14918	3853	0.35
chr6_44105722_44105873	0.83	Gm35216	predicted gene, 35216	22442	0.28
chr8_106607096_106607247	0.83	Cdh1	cadherin 1	3028	0.23
chr19_23143541_23144062	0.82	Klf9	Kruppel-like factor 9	157	0.95
chr5_35727822_35729089	0.81	Sh3tc1	SH3 domain and tetratricopeptide repeats 1	557	0.73
chr10_81328518_81330009	0.80	Tbxa2r	thromboxane A2 receptor	532	0.47
chr1_125431760_125432298	0.78	Actr3	ARP3 actin-related protein 3	2617	0.33
chr6_15405115_15405989	0.77	Gm25470	predicted gene, 25470	571	0.83
chr1_173801485_173801725	0.77	Ifi203-ps	interferon activated gene 203, pseudogene	3335	0.17
chr5_61905658_61905809	0.76	G6pd2	glucose-6-phosphate dehydrogenase 2	96917	0.08
chr19_36114670_36114821	0.72	Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	5165	0.21
chr5_46033018_46033485	0.72	4930405L22Rik	RIKEN cDNA 4930405L22 gene	100842	0.07
chr15_99848312_99848463	0.71	Lima1	LIM domain and actin binding 1	26284	0.07
chr10_126143996_126144329	0.71	Gm4510	predicted gene 4510	42161	0.18
chrX_164144317_164144468	0.70	Ace2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	3914	0.21
chr5_119846002_119846206	0.69	Tbx5	T-box 5	9949	0.17
chr14_99772626_99773392	0.67	Gm22970	predicted gene, 22970	799	0.67
chr3_131334397_131335246	0.67	Sgms2	sphingomyelin synthase 2	10112	0.15
chr5_36396690_36396841	0.67	Sorcs2	sortilin-related VPS10 domain containing receptor 2	1342	0.46
chr11_65143082_65143421	0.65	1700086D15Rik	RIKEN cDNA 1700086D15 gene	16639	0.13
chr7_134498821_134499325	0.63	D7Ertd443e	DNA segment, Chr 7, ERATO Doi 443, expressed	89	0.98
chr6_64649585_64650116	0.63	Grid2	glutamate receptor, ionotropic, delta 2	13338	0.27
chr18_38592430_38592730	0.63	Spry4	sprouty RTK signaling antagonist 4	8835	0.16
chr4_57571014_57571165	0.63	Pakap	paralemmin A kinase anchor protein	2759	0.37
chr5_101381446_101381597	0.63	Cycs-ps2	cytochrome c, pseudogene 2	75943	0.11
chr4_76453237_76453446	0.62	Gm42303	predicted gene, 42303	2110	0.34
chr16_97461693_97461844	0.61	Mx1	MX dynamin-like GTPase 1	910	0.47
chr4_41661471_41661697	0.61	Cntfr	ciliary neurotrophic factor receptor	2450	0.15
chr12_63552794_63553211	0.61	Gm48417	predicted gene, 48417	18861	0.25
chr5_14027948_14028480	0.59	Gm43519	predicted gene 43519	320	0.88
chr7_112681736_112682136	0.59	2310014F06Rik	RIKEN cDNA 2310014F06 gene	1855	0.27
chr16_4520955_4521652	0.58	Srl	sarcalumenin	1760	0.3
chr1_57613110_57613752	0.58	Gm17929	predicted gene, 17929	49380	0.14
chr1_59766087_59766553	0.57	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	2920	0.2
chr14_67229549_67230710	0.56	Gm20675	predicted gene 20675	3000	0.21
chr12_59129998_59130231	0.56	Mia2	MIA SH3 domain ER export factor 2	263	0.88
chr4_81566393_81566794	0.56	Gm11765	predicted gene 11765	104861	0.07
chr17_45689173_45689324	0.56	Tmem63b	transmembrane protein 63b	2343	0.17
chr3_89436767_89437632	0.55	Pbxip1	pre B cell leukemia transcription factor interacting protein 1	443	0.64
chr18_4923350_4923782	0.55	Svil	supervillin	1840	0.48
chr13_49608792_49609347	0.55	Ogn	osteoglycin	1023	0.44
chr10_80985153_80986200	0.55	Gng7	guanine nucleotide binding protein (G protein), gamma 7	12514	0.09
chr4_44776724_44776875	0.54	Zcchc7	zinc finger, CCHC domain containing 7	16355	0.16
chr5_147723576_147724353	0.54	Flt1	FMS-like tyrosine kinase 1	2024	0.35
chr10_43830540_43831081	0.54	4933404K13Rik	RIKEN cDNA 4933404K13 gene	4230	0.19
chr19_34253411_34255499	0.54	Acta2	actin, alpha 2, smooth muscle, aorta	225	0.92
chr3_79887847_79889192	0.53	Gm36569	predicted gene, 36569	1713	0.31
chr11_114185237_114185641	0.53	1700001J04Rik	RIKEN cDNA 1700001J04 gene	1235	0.46
chr14_103514572_103514723	0.53	Scel	sciellin	1226	0.53
chr10_28074317_28074675	0.53	Ptprk	protein tyrosine phosphatase, receptor type, K	324	0.91
chr8_125102195_125102676	0.52	Disc1	disrupted in schizophrenia 1	14448	0.19
chr11_96190174_96190661	0.52	Hoxb13	homeobox B13	3899	0.13
chr16_26369170_26369694	0.51	Cldn1	claudin 1	2409	0.41
chr3_60408400_60409132	0.51	Mbnl1	muscleblind like splicing factor 1	64064	0.12
chr11_51291972_51292123	0.51	Col23a1	collagen, type XXIII, alpha 1	2127	0.26
chr15_85205740_85207341	0.50	Fbln1	fibulin 1	535	0.78
chr6_36389491_36389642	0.50	9330158H04Rik	RIKEN cDNA 9330158H04 gene	139	0.94
chrX_157707743_157707894	0.50	Smpx	small muscle protein, X-linked	5220	0.17
chr19_3853794_3854481	0.50	Gm16066	predicted gene 16066	1718	0.18
chr12_110381274_110381502	0.50	Gm47195	predicted gene, 47195	56003	0.08
chr6_52005555_52005706	0.50	Skap2	src family associated phosphoprotein 2	6885	0.17
chr15_42623782_42623933	0.49	Gm17473	predicted gene, 17473	52384	0.15
chr17_81723281_81723432	0.49	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	15021	0.27
chr7_68278547_68278698	0.49	Gm16157	predicted gene 16157	2028	0.23
chr12_73586142_73586320	0.49	Prkch	protein kinase C, eta	1388	0.43
chr9_24766942_24767354	0.49	Tbx20	T-box 20	2532	0.28
chr10_20723991_20725012	0.48	Pde7b	phosphodiesterase 7B	195	0.96
chr15_56695618_56696135	0.48	Has2	hyaluronan synthase 2	1337	0.43
chr2_108131521_108131672	0.48	Gm23749	predicted gene, 23749	51554	0.18
chr13_23914209_23914456	0.48	Slc17a4	solute carrier family 17 (sodium phosphate), member 4	636	0.52
chr13_31627499_31628464	0.48	Gm27516	predicted gene, 27516	1438	0.26
chr6_39474108_39474259	0.48	Dennd2a	DENN/MADD domain containing 2A	3859	0.19
chr11_115836836_115837044	0.47	Llgl2	LLGL2 scribble cell polarity complex component	2617	0.15
chr13_51611070_51611510	0.47	Cks2	CDC28 protein kinase regulatory subunit 2	33942	0.13
chr13_81828595_81828746	0.46	Cetn3	centrin 3	36693	0.15
chr5_20451812_20452080	0.46	Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2	81554	0.1
chr11_36277031_36277877	0.46	Gm12127	predicted gene 12127	587	0.85
chr2_20521781_20522182	0.46	Etl4	enhancer trap locus 4	2153	0.43
chr10_88502011_88502741	0.45	Chpt1	choline phosphotransferase 1	1377	0.37
chr6_112273463_112275203	0.45	Lmcd1	LIM and cysteine-rich domains 1	575	0.71
chr8_12926230_12928559	0.45	Mcf2l	mcf.2 transforming sequence-like	762	0.52
chr10_81195163_81195734	0.45	Atcayos	ataxia, cerebellar, Cayman type, opposite strand	757	0.35
chr2_116075452_116076592	0.45	2810405F15Rik	RIKEN cDNA 2810405F15 gene	74	0.97
chr11_110968533_110968684	0.44	Kcnj16	potassium inwardly-rectifying channel, subfamily J, member 16	544	0.87
chr17_85375214_85375365	0.44	Rpl31-ps16	ribosomal protein L31, pseudogene 16	123344	0.05
chr5_24731546_24731845	0.44	Wdr86	WD repeat domain 86	968	0.47
chr5_66080287_66081072	0.44	Rbm47	RNA binding motif protein 47	305	0.84
chr19_17834325_17834699	0.44	Pcsk5	proprotein convertase subtilisin/kexin type 5	3105	0.24
chr3_19306199_19306444	0.43	Pde7a	phosphodiesterase 7A	4582	0.29
chr18_77776084_77776500	0.43	Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	2300	0.2
chr14_58073809_58074297	0.43	Fgf9	fibroblast growth factor 9	1062	0.51
chr11_83849571_83850989	0.43	Hnf1b	HNF1 homeobox B	217	0.83
chr14_20891990_20892476	0.42	Gm6128	predicted pseudogene 6128	35812	0.13
chr11_85427959_85428376	0.42	Bcas3	breast carcinoma amplified sequence 3	37992	0.17
chrX_41063710_41063861	0.42	Gm14576	predicted gene 14576	135674	0.05
chr13_46422196_46422985	0.42	Rbm24	RNA binding motif protein 24	768	0.72
chr15_6861862_6862444	0.41	Osmr	oncostatin M receptor	12104	0.28
chr1_45500349_45500721	0.41	Col5a2	collagen, type V, alpha 2	2747	0.22
chr14_60506229_60506951	0.41	Gm29266	predicted gene 29266	21382	0.2
chr2_138277835_138280637	0.40	Btbd3	BTB (POZ) domain containing 3	743	0.81
chr4_31877174_31877467	0.40	Map3k7	mitogen-activated protein kinase kinase kinase 7	86777	0.09
chr8_61902711_61903006	0.40	Palld	palladin, cytoskeletal associated protein	168	0.95
chr3_101598645_101599448	0.40	Gm42941	predicted gene 42941	1916	0.31
chr7_104314930_104315471	0.40	Trim12a	tripartite motif-containing 12A	143	0.53
chr17_65540372_65540935	0.40	Tmem232	transmembrane protein 232	91	0.96
chr10_33084458_33084609	0.40	Trdn	triadin	972	0.66
chrX_77616014_77616165	0.40	Gm23121	predicted gene, 23121	36602	0.15
chr13_45692562_45692845	0.40	Gm47460	predicted gene, 47460	56869	0.15
chr10_89769073_89769465	0.40	Uhrf1bp1l	UHRF1 (ICBP90) binding protein 1-like	17931	0.18
chr3_30514092_30514862	0.39	Mecom	MDS1 and EVI1 complex locus	4655	0.16
chr1_45765924_45766119	0.39	Gm8307	predicted gene 8307	2316	0.22
chr11_69419130_69420636	0.39	Kdm6b	KDM1 lysine (K)-specific demethylase 6B	6208	0.09
chr2_91119045_91119896	0.39	Mybpc3	myosin binding protein C, cardiac	1326	0.3
chr1_135839024_135839175	0.39	Tnnt2	troponin T2, cardiac	1600	0.28
chr5_147563744_147564584	0.38	Pan3	PAN3 poly(A) specific ribonuclease subunit	24887	0.17
chr16_78326082_78326665	0.38	Cxadr	coxsackie virus and adenovirus receptor	1166	0.43
chr9_97056372_97056523	0.38	Gm19325	predicted gene, 19325	10860	0.13
chr11_96326559_96328109	0.38	Hoxb3	homeobox B3	728	0.39
chr3_27687255_27687406	0.38	Fndc3b	fibronectin type III domain containing 3B	23068	0.24
chr6_4506970_4507670	0.38	Gm43921	predicted gene, 43921	1233	0.34
chr16_23102639_23103369	0.38	Eif4a2	eukaryotic translation initiation factor 4A2	4440	0.07
chr1_173739285_173739489	0.38	Ifi207	interferon activated gene 207	2360	0.2
chr3_122566763_122566972	0.38	Gm43569	predicted gene 43569	1817	0.23
chr3_128192124_128192781	0.38	D030025E07Rik	RIKEN cDNA D030025E07 gene	39101	0.18
chr11_108224470_108224622	0.37	Gm11655	predicted gene 11655	42696	0.17
chr14_121983497_121983648	0.37	Gpr183	G protein-coupled receptor 183	18377	0.16
chrX_9467805_9468124	0.37	Cybb	cytochrome b-245, beta polypeptide	1305	0.48
chr11_96306504_96308444	0.37	Hoxb5os	homeobox B5 and homeobox B6, opposite strand	564	0.48
chr12_108370973_108372659	0.37	Eml1	echinoderm microtubule associated protein like 1	859	0.58
chr5_103393811_103394094	0.37	Ptpn13	protein tyrosine phosphatase, non-receptor type 13	31240	0.14
chr9_44655251_44655818	0.37	Gm47238	predicted gene, 47238	4613	0.08
chr8_47994470_47995597	0.37	Wwc2	WW, C2 and coiled-coil domain containing 2	4109	0.22
chr4_15172194_15172551	0.37	Gm11845	predicted gene 11845	17980	0.21
chrX_169037778_169038469	0.37	Arhgap6	Rho GTPase activating protein 6	1512	0.52
chr5_77092587_77093501	0.37	Hopxos	HOP homeobox, opposite strand	1488	0.28
chr2_4917518_4918021	0.36	Phyh	phytanoyl-CoA hydroxylase	1250	0.37
chr10_45288857_45289008	0.36	Popdc3	popeye domain containing 3	373	0.55
chr6_48705812_48706743	0.36	Gimap6	GTPase, IMAP family member 6	41	0.93
chr8_57213759_57214585	0.36	Gm17994	predicted gene, 17994	77880	0.08
chr4_55533366_55533571	0.36	Klf4	Kruppel-like factor 4 (gut)	1002	0.5
chr16_52081920_52082231	0.36	Gm23513	predicted gene, 23513	23072	0.21
chr15_7574807_7574958	0.36	Gm49206	predicted gene, 49206	1360	0.56
chr10_91249578_91250191	0.36	Gm18705	predicted gene, 18705	9460	0.17
chr10_50900495_50901766	0.35	Sim1	single-minded family bHLH transcription factor 1	5479	0.29
chr17_81737002_81738450	0.35	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	651	0.81
chr10_78165962_78166113	0.35	Gatd3a	glutamine amidotransferase like class 1 domain containing 3A	1405	0.3
chr9_79875436_79876355	0.35	Gm3211	predicted gene 3211	37305	0.12
chr2_167691999_167692442	0.35	A530013C23Rik	RIKEN cDNA A530013C23 gene	1039	0.35
chr10_107901520_107901895	0.35	Otogl	otogelin-like	10427	0.26
chr3_151835993_151836144	0.35	Ptgfr	prostaglandin F receptor	45	0.88
chr2_163396823_163398215	0.34	Jph2	junctophilin 2	430	0.77
chr10_19170810_19170961	0.34	Gm20139	predicted gene, 20139	3647	0.24
chr3_9831684_9831843	0.34	Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	1600	0.33
chr3_51271701_51271852	0.34	4930577N17Rik	RIKEN cDNA 4930577N17 gene	4983	0.13
chr15_51083609_51083844	0.34	Gm48913	predicted gene, 48913	186087	0.03
chr9_49485451_49486485	0.34	Ttc12	tetratricopeptide repeat domain 12	247	0.93
chr2_29967054_29967205	0.34	Sptan1	spectrin alpha, non-erythrocytic 1	1446	0.28
chr9_77044568_77044781	0.34	Tinag	tubulointerstitial nephritis antigen	1075	0.46
chr19_46714952_46715103	0.34	As3mt	arsenic (+3 oxidation state) methyltransferase	3055	0.19
chr15_80367018_80367304	0.33	Cacna1i	calcium channel, voltage-dependent, alpha 1I subunit	22167	0.16
chr1_44217202_44217360	0.33	Mettl21e	methyltransferase like 21E	1632	0.34
chr10_80584595_80587584	0.33	Abhd17a	abhydrolase domain containing 17A	535	0.53
chr4_92859969_92860120	0.33	Gm22605	predicted gene, 22605	6538	0.32
chr4_141242265_141243901	0.33	Arhgef19	Rho guanine nucleotide exchange factor (GEF) 19	190	0.9
chr19_25249376_25249588	0.32	Kank1	KN motif and ankyrin repeat domains 1	12507	0.24
chr2_76980010_76980504	0.32	Ttn	titin	75	0.98
chr17_12760964_12761214	0.32	Igf2r	insulin-like growth factor 2 receptor	8575	0.12
chr2_65233164_65233335	0.32	Cobll1	Cobl-like 1	2746	0.25
chr5_30593992_30594194	0.32	Gm9899	predicted gene 9899	5474	0.14
chr14_63235525_63236294	0.32	Gata4	GATA binding protein 4	9339	0.17
chr13_81351343_81352153	0.32	Adgrv1	adhesion G protein-coupled receptor V1	122	0.98
chr10_4080039_4080600	0.32	Gm25515	predicted gene, 25515	23994	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.2	0.6	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.2	0.8	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.1	0.4	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.4	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.1	0.5	GO:1900212	mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.1	0.2	GO:0048793	pronephros development(GO:0048793)
0.1	0.4	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	0.5	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	0.4	GO:0031033	myosin filament organization(GO:0031033)
0.1	0.6	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.1	0.4	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.1	0.3	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.4	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.1	0.3	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1	0.5	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.3	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.3	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.4	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
0.1	1.3	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.2	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1	0.3	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.1	0.3	GO:1903416	response to glycoside(GO:1903416)
0.1	0.2	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.1	0.2	GO:0003180	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.1	0.2	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.8	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.4	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.1	0.3	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	0.3	GO:0030035	microspike assembly(GO:0030035)
0.1	0.2	GO:0032439	endosome localization(GO:0032439)
0.1	0.2	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1	0.2	GO:0014738	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1	0.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.3	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1	0.1	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.1	0.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.1	0.2	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.1	0.1	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1	0.2	GO:0046959	habituation(GO:0046959)
0.1	0.2	GO:0060066	oviduct development(GO:0060066)
0.1	0.1	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.4	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.1	GO:0021557	oculomotor nerve development(GO:0021557) trochlear nerve development(GO:0021558)
0.0	0.6	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0	0.1	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
0.0	0.2	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.2	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.1	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.7	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.0	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.2	GO:0033153	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0	0.1	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.0	GO:0014820	tonic smooth muscle contraction(GO:0014820)
0.0	0.1	GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.0	0.2	GO:0034351	negative regulation of glial cell apoptotic process(GO:0034351)
0.0	0.1	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0	0.1	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.0	0.1	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.1	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.7	GO:0014829	vascular smooth muscle contraction(GO:0014829)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.3	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.3	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.2	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0003177	pulmonary valve development(GO:0003177) pulmonary valve morphogenesis(GO:0003184)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.1	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.3	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:2000591	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.3	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.1	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.1	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0032252	secretory granule localization(GO:0032252)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	1.8	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.1	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0	0.1	GO:0051385	response to mineralocorticoid(GO:0051385)
0.0	0.0	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.1	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.2	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.0	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.2	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.2	GO:0035994	response to muscle stretch(GO:0035994)
0.0	0.1	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.0	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.1	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.1	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.2	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.0	GO:0060847	endothelial cell fate specification(GO:0060847)
0.0	0.0	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.0	GO:1901535	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0	0.2	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.0	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.0	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.0	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.5	GO:0006940	regulation of smooth muscle contraction(GO:0006940)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.4	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
0.0	0.0	GO:0003175	tricuspid valve development(GO:0003175)
0.0	0.0	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.0	GO:0007494	midgut development(GO:0007494)
0.0	0.2	GO:0007625	grooming behavior(GO:0007625)
0.0	0.0	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0	0.3	GO:0055090	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.0	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.0	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.1	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0	0.0	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.0	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.0	0.0	GO:0052041	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.0	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.0	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.0	GO:0035799	ureter maturation(GO:0035799)
0.0	0.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.0	GO:1904238	pericyte cell differentiation(GO:1904238)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.0	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.0	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	1.0	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.4	GO:0071953	elastic fiber(GO:0071953)
0.1	0.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	0.2	GO:1990696	USH2 complex(GO:1990696)
0.1	0.2	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0043219	lateral loop(GO:0043219)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.6	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0000802	transverse filament(GO:0000802)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.6	GO:0036379	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0	0.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.1	GO:0044462	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0016460	myosin II complex(GO:0016460)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.3	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.7	GO:0031672	A band(GO:0031672)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.1	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.4	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	1.3	GO:0044449	contractile fiber part(GO:0044449)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.4	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2	0.9	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.3	GO:0051373	FATZ binding(GO:0051373)
0.1	0.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.2	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.4	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.7	GO:0004954	prostanoid receptor activity(GO:0004954)
0.1	0.3	GO:1990239	steroid hormone binding(GO:1990239)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.2	GO:0009374	biotin binding(GO:0009374)
0.1	0.4	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	2.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.2	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.7	GO:0052714	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.5	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.2	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.2	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.6	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.6	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.1	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0038100	nodal binding(GO:0038100)
0.0	0.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.4	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.0	GO:0036403	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.0	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.0	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.2	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.7	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
1.3	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.4	NABA COLLAGENS	Genes encoding collagen proteins
0.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.6	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC