Project

ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nr4a3

Z-value: 0.34

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Transcription factors associated with Nr4a3

Gene Symbol	Gene ID	Gene Info
Nr4a3 Ensembl NCBI MGI UniProt	ENSMUSG00000028341.3	Nr4a3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Nr4a3	chr4_48045374_48045835	373	0.892613	0.47	1.7e-04	Click!
Nr4a3	chr4_48046053_48046770	1180	0.547031	0.43	5.6e-04	Click!
Nr4a3	chr4_48046885_48047647	1848	0.400614	0.38	2.5e-03	Click!
Nr4a3	chr4_48047901_48049197	565	0.804093	0.35	6.3e-03	Click!
Nr4a3	chr4_48051161_48052389	527	0.823037	0.27	3.5e-02	Click!

Activity of the Nr4a3 motif across conditions

Conditions sorted by the z-value of the Nr4a3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrX_170674573_170675954	1.51	Asmt	acetylserotonin O-methyltransferase	2619	0.41
chr6_53817061_53817543	0.73	Gm16499	predicted gene 16499	1441	0.39
chr19_59461344_59461892	0.73	Emx2	empty spiracles homeobox 2	1184	0.42
chr7_99270744_99271357	0.55	Map6	microtubule-associated protein 6	1918	0.23
chr13_28948354_28948958	0.52	Sox4	SRY (sex determining region Y)-box 4	5057	0.24
chr13_53469792_53470715	0.50	Msx2	msh homeobox 2	2821	0.27
chr12_72234504_72235243	0.47	Rtn1	reticulon 1	866	0.66
chr3_84303363_84303817	0.47	Trim2	tripartite motif-containing 2	1151	0.59
chr14_59626952_59628434	0.44	Shisa2	shisa family member 2	504	0.76
chr5_107498769_107499247	0.41	Btbd8	BTB (POZ) domain containing 8	1229	0.33
chr2_6883618_6884699	0.41	Gm13389	predicted gene 13389	112	0.85
chr9_41376046_41377501	0.39	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	212	0.93
chr10_21882056_21883261	0.38	Sgk1	serum/glucocorticoid regulated kinase 1	289	0.9
chr9_91386509_91387874	0.37	Zic4	zinc finger protein of the cerebellum 4	4781	0.14
chr3_5213504_5214063	0.37	Gm10748	predicted gene 10748	945	0.56
chr13_31627499_31628464	0.36	Gm27516	predicted gene, 27516	1438	0.26
chr18_15060980_15061427	0.35	Kctd1	potassium channel tetramerisation domain containing 1	686	0.74
chr15_101438228_101439215	0.35	Krt87	keratin 87	83	0.92
chr15_98983254_98984205	0.35	4930578M01Rik	RIKEN cDNA 4930578M01 gene	102	0.93
chrX_136957431_136958031	0.35	Tmsb15b2	thymosin beta 15b2	294	0.8
chr1_62709496_62710533	0.34	Nrp2	neuropilin 2	6312	0.18
chr3_152106774_152107680	0.34	Gipc2	GIPC PDZ domain containing family, member 2	195	0.8
chr10_14759598_14760682	0.33	Nmbr	neuromedin B receptor	17	0.91
chr1_120604474_120605877	0.32	En1	engrailed 1	2757	0.3
chr11_85838795_85841602	0.32	Tbx2	T-box 2	7647	0.13
chr2_52860105_52860808	0.30	Fmnl2	formin-like 2	2588	0.39
chr12_117153278_117156362	0.30	Gm10421	predicted gene 10421	3169	0.37
chr9_43310784_43311614	0.29	Trim29	tripartite motif-containing 29	351	0.87
chr19_44496549_44496948	0.29	Wnt8b	wingless-type MMTV integration site family, member 8B	3276	0.18
chr3_34641628_34643070	0.29	Gm42692	predicted gene 42692	915	0.41
chr10_39532030_39532710	0.29	Fyn	Fyn proto-oncogene	900	0.6
chr2_32605823_32605974	0.28	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	1063	0.28
chr18_54493213_54493765	0.28	4933434P08Rik	RIKEN cDNA 4933434P08 gene	3095	0.29
chr1_93158156_93158394	0.28	Mab21l4	mab-21-like 4	2595	0.19
chr2_91930544_91931926	0.27	Mdk	midkine	453	0.69
chr2_165137192_165137398	0.27	Gm14397	predicted gene 14397	22117	0.14
chr15_86028772_86030702	0.27	Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1	4466	0.22
chr8_94995272_94995731	0.27	Adgrg1	adhesion G protein-coupled receptor G1	160	0.93
chr5_134101487_134102203	0.27	Castor2	cytosolic arginine sensor for mTORC1 subunit 2	1840	0.26
chr9_27303775_27304036	0.27	Igsf9b	immunoglobulin superfamily, member 9B	4677	0.22
chr10_91967800_91968283	0.27	Gm31592	predicted gene, 31592	79212	0.1
chr9_71896189_71896351	0.26	Tcf12	transcription factor 12	126	0.93
chr3_53043747_53045351	0.26	Gm42901	predicted gene 42901	2794	0.16
chr4_150730352_150730536	0.25	Gm16079	predicted gene 16079	51652	0.12
chr15_77303570_77303965	0.25	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	2838	0.22
chr1_167687127_167687278	0.25	Lmx1a	LIM homeobox transcription factor 1 alpha	2035	0.44
chr9_91352783_91353195	0.25	A730094K22Rik	RIKEN cDNA A730094K22 gene	2036	0.19
chr16_11068986_11070445	0.25	Snn	stannin	3385	0.13
chrX_136976179_136976867	0.25	Tmsb15l	thymosin beta 15b like	346	0.41
chr7_29310756_29310907	0.24	Dpf1	D4, zinc and double PHD fingers family 1	1225	0.31
chr5_111580966_111582197	0.24	C130026L21Rik	RIKEN cDNA C130026L21 gene	13	0.98
chrX_7919510_7921219	0.24	Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor	542	0.52
chr11_79662174_79662700	0.24	Rab11fip4	RAB11 family interacting protein 4 (class II)	1875	0.21
chr2_29046202_29046836	0.23	Cfap77	cilia and flagella associated protein 77	7159	0.17
chr4_154600279_154600535	0.23	Gm13134	predicted gene 13134	790	0.58
chr1_188149633_188149810	0.23	Gm38315	predicted gene, 38315	10986	0.27
chr5_103393811_103394094	0.23	Ptpn13	protein tyrosine phosphatase, non-receptor type 13	31240	0.14
chr5_45638962_45640180	0.22	Fam184b	family with sequence similarity 184, member B	43	0.69
chr1_106710395_106710955	0.22	Bcl2	B cell leukemia/lymphoma 2	2504	0.31
chr9_111440499_111440650	0.22	Dclk3	doublecortin-like kinase 3	1493	0.42
chr3_156564902_156565177	0.22	Negr1	neuronal growth regulator 1	2889	0.27
chr11_88071226_88071740	0.22	Vezf1	vascular endothelial zinc finger 1	2105	0.21
chr17_33962389_33962540	0.22	Vps52	VPS52 GARP complex subunit	716	0.29
chr10_79636527_79636678	0.21	Gm47163	predicted gene, 47163	1254	0.21
chr2_110949491_110950578	0.21	Ano3	anoctamin 3	338	0.92
chr1_44199495_44199646	0.21	Gm15833	predicted gene 15833	12592	0.15
chr16_95673997_95674148	0.21	Ets2	E26 avian leukemia oncogene 2, 3' domain	28003	0.19
chr4_22480645_22481269	0.21	Pou3f2	POU domain, class 3, transcription factor 2	7409	0.17
chr11_21999976_22000574	0.21	Otx1	orthodenticle homeobox 1	1340	0.53
chr12_3891782_3892977	0.21	Dnmt3a	DNA methyltransferase 3A	635	0.69
chr14_98164357_98165375	0.21	Dach1	dachshund family transcription factor 1	4677	0.28
chr2_25708979_25709130	0.21	A230005M16Rik	RIKEN cDNA A230005M16 gene	662	0.44
chr2_181313043_181314281	0.21	Stmn3	stathmin-like 3	838	0.42
chr6_13835523_13837039	0.21	Gpr85	G protein-coupled receptor 85	960	0.59
chr7_93085111_93085503	0.21	Gm9934	predicted gene 9934	4280	0.2
chr10_45808761_45809150	0.20	D030045P18Rik	RIKEN cDNA D030045P18 gene	1251	0.49
chr3_87949543_87950464	0.20	Crabp2	cellular retinoic acid binding protein II	1337	0.25
chr19_5606660_5606811	0.20	Kat5	K(lysine) acetyltransferase 5	1535	0.19
chr15_103522891_103523042	0.20	Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	752	0.57
chr6_55010251_55010633	0.20	Ggct	gamma-glutamyl cyclotransferase	17492	0.15
chr3_86858235_86858443	0.20	Gm37025	predicted gene, 37025	6153	0.21
chr5_144547334_144548656	0.20	Nptx2	neuronal pentraxin 2	2093	0.41
chr11_77936512_77937218	0.20	Sez6	seizure related gene 6	5826	0.14
chr18_43175442_43176118	0.20	4930588A03Rik	RIKEN cDNA 4930588A03 gene	4506	0.2
chr6_127870846_127870997	0.20	Gm38901	predicted gene, 38901	6325	0.16
chr17_17830971_17831711	0.19	Spaca6	sperm acrosome associated 6	103	0.78
chr8_25545899_25546050	0.19	Gm16159	predicted gene 16159	7586	0.11
chr8_47284401_47285223	0.19	Stox2	storkhead box 2	4550	0.27
chr10_81417616_81418054	0.19	Mir1191b	microRNA 1191b	1538	0.15
chr13_46161372_46162144	0.19	Gm10113	predicted gene 10113	29288	0.21
chr19_15903714_15904400	0.19	Psat1	phosphoserine aminotransferase 1	5655	0.23
chr12_73043242_73043393	0.19	Six1	sine oculis-related homeobox 1	502	0.81
chr11_23495316_23495877	0.18	Ahsa2	AHA1, activator of heat shock protein ATPase 2	1942	0.18
chr1_194622071_194623282	0.18	Plxna2	plexin A2	2851	0.26
chr2_74691003_74692289	0.18	Hoxd10	homeobox D10	278	0.7
chr10_80188763_80188923	0.18	Efna2	ephrin A2	9361	0.08
chr2_13129875_13130250	0.18	Gm38156	predicted gene, 38156	11627	0.19
chr13_72632318_72633242	0.18	Irx2	Iroquois homeobox 2	183	0.95
chr2_170734259_170734932	0.18	Dok5	docking protein 5	2788	0.35
chr8_84178723_84178952	0.18	Mir181d	microRNA 181d	50	0.57
chr2_157696327_157696590	0.18	Gm25407	predicted gene, 25407	17343	0.16
chr5_26210819_26210970	0.18	Gm7361	predicted gene 7361	46797	0.13
chr7_128474182_128474654	0.18	Gm32816	predicted gene, 32816	200	0.89
chr11_120293329_120293641	0.18	Bahcc1	BAH domain and coiled-coil containing 1	3692	0.13
chr10_67094914_67095382	0.18	Jmjd1c	jumonji domain containing 1C	977	0.49
chr2_33369536_33369687	0.18	Ralgps1	Ral GEF with PH domain and SH3 binding motif 1	1818	0.3
chr7_126364984_126365135	0.17	Lat	linker for activation of T cells	173	0.89
chr11_101084072_101084686	0.17	Coasy	Coenzyme A synthase	484	0.59
chr7_45304558_45305606	0.17	Trpm4	transient receptor potential cation channel, subfamily M, member 4	122	0.9
chr1_159524626_159524870	0.17	Tnr	tenascin R	907	0.65
chr5_138606179_138606361	0.17	Gm24082	predicted gene, 24082	429	0.59
chr16_94141250_94141643	0.17	Sim2	single-minded family bHLH transcription factor 2	16265	0.12
chr13_52976109_52977372	0.17	Nfil3	nuclear factor, interleukin 3, regulated	4333	0.2
chr6_120716777_120717027	0.17	Cecr2	CECR2, histone acetyl-lysine reader	17656	0.17
chr3_132017605_132018083	0.17	Gm22421	predicted gene, 22421	64548	0.12
chr18_37755572_37756990	0.17	Gm26672	predicted gene, 26672	67	0.83
chr2_27353287_27353438	0.17	Vav2	vav 2 oncogene	8882	0.17
chr13_23552480_23553015	0.17	H1f3	H1.3 linker histone, cluster member	515	0.38
chr9_42121573_42122781	0.17	Sorl1	sortilin-related receptor, LDLR class A repeats-containing	2120	0.33
chr4_24245083_24245586	0.17	Gm11892	predicted gene 11892	7234	0.32
chr1_118983510_118983661	0.17	Gli2	GLI-Kruppel family member GLI2	997	0.6
chr2_180343222_180343937	0.16	Gata5	GATA binding protein 5	8880	0.12
chr17_35909041_35910037	0.16	Atat1	alpha tubulin acetyltransferase 1	34	0.91
chr6_37592234_37592983	0.16	Gm7463	predicted gene 7463	51194	0.14
chr17_35244956_35245392	0.16	Mir6975	microRNA 6975	1099	0.17
chr18_43394505_43395255	0.16	Dpysl3	dihydropyrimidinase-like 3	1503	0.46
chr19_17834325_17834699	0.16	Pcsk5	proprotein convertase subtilisin/kexin type 5	3105	0.24
chr12_111694916_111695235	0.16	Gm36635	predicted gene, 36635	8007	0.1
chr12_118855278_118855595	0.16	Sp8	trans-acting transcription factor 8	7850	0.22
chr14_52016551_52017265	0.16	Tmem253	transmembrane protein 253	11	0.93
chr8_114603657_114603808	0.16	Wwox	WW domain-containing oxidoreductase	4704	0.23
chr16_33941271_33941422	0.16	Itgb5	integrin beta 5	5178	0.18
chr3_94480513_94480707	0.16	Riiad1	regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1	269	0.78
chr1_75313516_75313667	0.16	Dnpep	aspartyl aminopeptidase	168	0.9
chr2_74732545_74733279	0.16	Hoxd3	homeobox D3	1	0.92
chr4_106915225_106915605	0.15	Ssbp3	single-stranded DNA binding protein 3	3117	0.27
chr15_83710142_83710772	0.15	Scube1	signal peptide, CUB domain, EGF-like 1	14469	0.21
chr18_60645927_60646078	0.15	Synpo	synaptopodin	2270	0.28
chr16_6841576_6842071	0.15	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	32601	0.26
chr2_25353478_25353940	0.15	Dpp7	dipeptidylpeptidase 7	835	0.33
chr2_127401705_127401856	0.15	Gpat2	glycerol-3-phosphate acyltransferase 2, mitochondrial	23419	0.12
chr4_139819504_139819950	0.15	Pax7	paired box 7	13280	0.22
chr19_22692617_22693990	0.15	Trpm3	transient receptor potential cation channel, subfamily M, member 3	481	0.87
chr19_46152579_46153392	0.15	Gbf1	golgi-specific brefeldin A-resistance factor 1	405	0.77
chr2_93641010_93641161	0.15	Alx4	aristaless-like homeobox 4	1299	0.54
chr2_74737192_74739622	0.15	Hoxd3	homeobox D3	1212	0.2
chr14_50896223_50897440	0.15	Klhl33	kelch-like 33	625	0.49
chr5_115585775_115585926	0.15	Gcn1	GCN1 activator of EIF2AK4	3453	0.13
chr13_94912810_94913359	0.15	Otp	orthopedia homeobox	30484	0.15
chr3_129194633_129194876	0.15	Pitx2	paired-like homeodomain transcription factor 2	5124	0.2
chr4_129226645_129228191	0.15	C77080	expressed sequence C77080	62	0.96
chr2_30137332_30137483	0.14	Tbc1d13	TBC1 domain family, member 13	377	0.75
chr2_4303011_4303677	0.14	Gm13187	predicted gene 13187	2177	0.24
chr5_96071564_96071715	0.14	Cnot6l	CCR4-NOT transcription complex, subunit 6-like	15294	0.23
chr17_44810813_44811180	0.14	Runx2	runt related transcription factor 2	3230	0.26
chr16_21205203_21206094	0.14	Ephb3	Eph receptor B3	893	0.56
chr5_13127277_13127474	0.14	Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	1782	0.32
chr2_30808018_30809041	0.14	Ntmt1	N-terminal Xaa-Pro-Lys N-methyltransferase 1	339	0.81
chr16_29054299_29054758	0.14	Gm8253	predicted gene 8253	103173	0.07
chr17_16483864_16484015	0.14	Gm4786	predicted gene 4786	73307	0.12
chr12_99229579_99229730	0.14	Gm19898	predicted gene, 19898	16017	0.18
chr10_13982681_13983672	0.14	Hivep2	human immunodeficiency virus type I enhancer binding protein 2	16152	0.19
chr11_69911679_69911838	0.14	Neurl4	neuralized E3 ubiquitin protein ligase 4	722	0.32
chr1_172485277_172486996	0.14	Igsf9	immunoglobulin superfamily, member 9	3822	0.12
chr13_78174144_78174519	0.14	3110006O06Rik	RIKEN cDNA 3110006O06 gene	2701	0.19
chr1_172206683_172207090	0.14	Pea15a	phosphoprotein enriched in astrocytes 15A	82	0.94
chr14_67414469_67414620	0.14	4930438E09Rik	RIKEN cDNA 4930438E09 gene	16802	0.17
chr6_84134951_84135267	0.14	Dysf	dysferlin	11638	0.19
chr10_110454344_110454630	0.13	Nav3	neuron navigator 3	1717	0.42
chr13_54685334_54685505	0.13	Rnf44	ring finger protein 44	1012	0.43
chr1_92177475_92177971	0.13	Hdac4	histone deacetylase 4	2574	0.37
chr1_172204323_172204753	0.13	Pea15a	phosphoprotein enriched in astrocytes 15A	2159	0.17
chr19_59452548_59452741	0.13	Emx2	empty spiracles homeobox 2	5728	0.17
chr1_106629507_106629751	0.13	Gm37053	predicted gene, 37053	22759	0.19
chr7_25402412_25402872	0.13	Lipe	lipase, hormone sensitive	3932	0.11
chr15_100825105_100825748	0.13	Gm35569	predicted gene, 35569	6965	0.16
chr2_157561445_157562129	0.13	Gm23134	predicted gene, 23134	660	0.4
chr4_129495840_129495991	0.13	Fam229a	family with sequence similarity 229, member A	4675	0.1
chr15_102512807_102512958	0.13	Map3k12	mitogen-activated protein kinase kinase kinase 12	2090	0.16
chr7_145222634_145222785	0.13	Smim38	small integral membrane protein 38	14590	0.2
chr7_126276115_126276973	0.13	Sbk1	SH3-binding kinase 1	3144	0.16
chr13_113918234_113918803	0.13	Arl15	ADP-ribosylation factor-like 15	123896	0.05
chr7_19634772_19634923	0.13	Clptm1	cleft lip and palate associated transmembrane protein 1	1330	0.24
chr2_164792559_164792710	0.13	Snx21	sorting nexin family member 21	982	0.28
chr11_109478129_109478280	0.13	Slc16a6	solute carrier family 16 (monocarboxylic acid transporters), member 6	4606	0.13
chr12_111412598_111413452	0.13	Exoc3l4	exocyst complex component 3-like 4	3992	0.14
chr11_120616897_120617872	0.13	Pcyt2	phosphate cytidylyltransferase 2, ethanolamine	485	0.48
chr16_34744940_34746455	0.13	Mylk	myosin, light polypeptide kinase	487	0.85
chr13_18948406_18949248	0.13	Amph	amphiphysin	429	0.8
chr15_79161202_79161377	0.13	Sox10	SRY (sex determining region Y)-box 10	3185	0.12
chr3_66972322_66972982	0.12	Shox2	short stature homeobox 2	5795	0.18
chr17_35907096_35907253	0.12	Atat1	alpha tubulin acetyltransferase 1	1787	0.11
chr4_134779342_134779493	0.12	Ldlrap1	low density lipoprotein receptor adaptor protein 1	11393	0.19
chr15_25407259_25407806	0.12	Basp1	brain abundant, membrane attached signal protein 1	6166	0.16
chr7_46399032_46399239	0.12	Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	1487	0.35
chr1_192190419_192191087	0.12	Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	21	0.98
chr7_28814945_28816569	0.12	Hnrnpl	heterogeneous nuclear ribonucleoprotein L	651	0.47
chr19_46714952_46715103	0.12	As3mt	arsenic (+3 oxidation state) methyltransferase	3055	0.19
chr6_137570111_137570964	0.12	Eps8	epidermal growth factor receptor pathway substrate 8	222	0.95
chr15_37432615_37433119	0.12	Gm15941	predicted gene 15941	203	0.91

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.1	0.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.2	GO:0030421	defecation(GO:0030421)
0.1	0.2	GO:0021586	pons maturation(GO:0021586)
0.1	0.2	GO:2001055	positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1	0.2	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.3	GO:0061551	trigeminal ganglion development(GO:0061551)
0.1	0.2	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.1	0.2	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.0	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.1	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.2	GO:0061591	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0	0.6	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.0	GO:0048880	sensory system development(GO:0048880)
0.0	0.1	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.4	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.0	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:2001201	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0	0.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.1	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:1902996	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.1	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.1	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.2	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0046959	habituation(GO:0046959)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.3	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.1	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.0	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.0	0.1	GO:0036005	response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.0	0.1	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.0	GO:0060460	left lung morphogenesis(GO:0060460) endodermal digestive tract morphogenesis(GO:0061031)
0.0	0.2	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.0	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.0	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.0	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.0	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.0	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.0	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.2	GO:0016486	peptide hormone processing(GO:0016486)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0072534	perineuronal net(GO:0072534)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)
0.0	0.1	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.4	GO:0031941	filamentous actin(GO:0031941)
0.0	0.0	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0097542	ciliary tip(GO:0097542)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.3	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.3	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.0	GO:0004083	bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.6	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR