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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Pax1_Pax9

Z-value: 0.72

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Transcription factors associated with Pax1_Pax9

Gene Symbol	Gene ID	Gene Info
Pax1 Ensembl NCBI MGI UniProt	ENSMUSG00000037034.9	paired box 1
Pax9 Ensembl NCBI MGI UniProt	ENSMUSG00000001497.12	paired box 9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_147364303_147364454	Pax1	616	0.631823	0.37	4.0e-03	Click!
chr2_147364921_147366397	Pax1	665	0.645814	0.34	8.0e-03	Click!
chr2_147364524_147364675	Pax1	395	0.796401	0.31	1.7e-02	Click!
chr2_147366625_147368623	Pax1	658	0.665183	0.21	1.1e-01	Click!
chr2_147370862_147371013	Pax1	2655	0.236025	0.20	1.3e-01	Click!
chr12_56680898_56682238	Pax9	10199	0.137937	0.29	2.5e-02	Click!
chr12_56704273_56704424	Pax9	8619	0.158329	0.22	9.0e-02	Click!
chr12_56695295_56695580	Pax9	202	0.917043	0.20	1.3e-01	Click!
chr12_56689059_56689356	Pax9	2560	0.210570	-0.19	1.4e-01	Click!
chr12_56699459_56700760	Pax9	4380	0.177339	0.15	2.4e-01	Click!

Activity of the Pax1_Pax9 motif across conditions

Conditions sorted by the z-value of the Pax1_Pax9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_38783979_38784442	1.93	Etv1	ets variant 1	701	0.73
chr3_84334737_84334991	1.93	Trim2	tripartite motif-containing 2	27987	0.19
chrX_86191680_86192868	1.76	Nr0b1	nuclear receptor subfamily 0, group B, member 1	510	0.82
chr18_13968574_13969239	1.73	Zfp521	zinc finger protein 521	2814	0.38
chr2_69129033_69129476	1.43	Nostrin	nitric oxide synthase trafficker	6546	0.22
chr3_122026883_122027085	1.42	Gm42544	predicted gene 42544	3154	0.22
chr1_187439655_187439905	1.36	Gm37896	predicted gene, 37896	8097	0.26
chr3_117360462_117360799	1.29	Plppr4	phospholipid phosphatase related 4	246	0.94
chr10_118415370_118415521	1.22	Ifng	interferon gamma	25601	0.12
chr3_142168419_142169229	1.19	Bmpr1b	bone morphogenetic protein receptor, type 1B	389	0.89
chr9_108479869_108480980	1.17	Lamb2	laminin, beta 2	543	0.5
chr18_69343988_69344332	1.15	Tcf4	transcription factor 4	14	0.99
chr11_43836528_43836860	1.08	Adra1b	adrenergic receptor, alpha 1b	362	0.91
chr7_144175485_144176434	1.07	Shank2	SH3 and multiple ankyrin repeat domains 2	430	0.88
chr17_56605990_56606141	1.03	Safb	scaffold attachment factor B	325	0.78
chr17_91085493_91086001	1.01	Gm47307	predicted gene, 47307	2659	0.21
chr7_48789069_48789872	1.01	Zdhhc13	zinc finger, DHHC domain containing 13	438	0.8
chr3_138069501_138070764	1.00	1110002E22Rik	RIKEN cDNA 1110002E22 gene	1465	0.3
chr11_69235499_69236586	0.97	Gucy2e	guanylate cyclase 2e	980	0.38
chr16_18628939_18629866	0.97	Septin5	septin 5	302	0.83
chr8_69328876_69329533	0.96	Gm7688	predicted gene 7688	14	0.97
chr18_62930968_62931119	0.96	Apcdd1	adenomatosis polyposis coli down-regulated 1	2467	0.29
chr2_156196155_156196567	0.95	Phf20	PHD finger protein 20	105	0.95
chr11_119251895_119252111	0.95	Ccdc40	coiled-coil domain containing 40	1550	0.27
chr16_75447524_75447796	0.94	Gm49678	predicted gene, 49678	367	0.91
chr6_21857914_21858140	0.92	Gm3289	predicted gene 3289	151	0.95
chr3_89322074_89322814	0.90	Efna3	ephrin A3	443	0.59
chr19_55380884_55381130	0.89	Vti1a	vesicle transport through interaction with t-SNAREs 1A	7	0.99
chr9_43744471_43744923	0.89	Nectin1	nectin cell adhesion molecule 1	53	0.93
chr6_124996427_124996698	0.86	Pianp	PILR alpha associated neural protein	132	0.9
chr1_154204657_154205754	0.85	Zfp648	zinc finger protein 648	4018	0.23
chr6_125690060_125690822	0.84	Ano2	anoctamin 2	22	0.98
chr11_87442706_87442946	0.84	Rnu3b1	U3B small nuclear RNA 1	411	0.65
chr13_96180631_96181081	0.83	Gm29543	predicted gene 29543	47487	0.12
chr5_142904389_142904540	0.82	Actb	actin, beta	810	0.55
chr17_75551472_75551866	0.82	Fam98a	family with sequence similarity 98, member A	127	0.98
chr4_137993078_137993287	0.82	Eif4g3	eukaryotic translation initiation factor 4 gamma, 3	160	0.97
chr2_4152602_4153854	0.81	Frmd4a	FERM domain containing 4A	356	0.79
chr12_28589414_28590093	0.81	Allc	allantoicase	7230	0.16
chr11_76849707_76849858	0.80	Cpd	carboxypeptidase D	2764	0.28
chr2_167189983_167190399	0.80	Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	36	0.9
chr5_111725272_111726064	0.80	Gm26897	predicted gene, 26897	8256	0.19
chr6_89345129_89345500	0.79	Gm44207	predicted gene, 44207	174	0.93
chr15_89147414_89148183	0.77	Mapk11	mitogen-activated protein kinase 11	621	0.51
chr6_145048452_145048971	0.76	Bcat1	branched chain aminotransferase 1, cytosolic	101	0.93
chr18_38992539_38992916	0.76	Arhgap26	Rho GTPase activating protein 26	418	0.79
chr1_25034283_25034476	0.76	Gm29414	predicted gene 29414	7147	0.21
chr13_49127551_49128199	0.76	Wnk2	WNK lysine deficient protein kinase 2	19357	0.2
chr6_47044703_47045103	0.76	Cntnap2	contactin associated protein-like 2	157	0.64
chr7_78884387_78884983	0.74	Mir7-2	microRNA 7-2	3592	0.14
chr9_35211266_35212010	0.74	Srpr	signal recognition particle receptor ('docking protein')	256	0.71
chr15_84104886_84106159	0.73	Sult4a1	sulfotransferase family 4A, member 1	87	0.93
chr2_84648361_84648948	0.73	Ctnnd1	catenin (cadherin associated protein), delta 1	117	0.92
chr9_63295779_63296191	0.72	Map2k5	mitogen-activated protein kinase kinase 5	7158	0.25
chr4_11558571_11558808	0.71	Rad54b	RAD54 homolog B (S. cerevisiae)	233	0.92
chr8_95533588_95534657	0.70	Ccdc113	coiled-coil domain containing 113	37	0.96
chr18_50035394_50035758	0.69	Tnfaip8	tumor necrosis factor, alpha-induced protein 8	4547	0.23
chr1_37719267_37719774	0.69	2010300C02Rik	RIKEN cDNA 2010300C02 gene	275	0.91
chr1_168393023_168393351	0.69	Pbx1	pre B cell leukemia homeobox 1	38317	0.16
chr4_140630650_140631291	0.68	Arhgef10l	Rho guanine nucleotide exchange factor (GEF) 10-like	13905	0.17
chr4_55928799_55929534	0.68	Gm12519	predicted gene 12519	64573	0.14
chr7_77132082_77132358	0.67	Gm44879	predicted gene 44879	166776	0.04
chr19_40894409_40894644	0.67	Mir8092	microRNA 8092	177	0.49
chr2_66100750_66100901	0.67	Galnt3	polypeptide N-acetylgalactosaminyltransferase 3	1658	0.38
chr6_49821912_49823056	0.66	Npy	neuropeptide Y	226	0.95
chr16_52448749_52449233	0.66	Alcam	activated leukocyte cell adhesion molecule	3474	0.38
chr8_125235887_125236799	0.66	Gm16237	predicted gene 16237	9020	0.28
chr2_77775323_77775836	0.64	Zfp385b	zinc finger protein 385B	41237	0.17
chr19_8839622_8840720	0.62	Bscl2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)	348	0.56
chr2_156477003_156477154	0.62	Epb41l1	erythrocyte membrane protein band 4.1 like 1	1544	0.28
chr14_32683979_32684180	0.62	3425401B19Rik	RIKEN cDNA 3425401B19 gene	1193	0.39
chr18_25067221_25067481	0.62	Fhod3	formin homology 2 domain containing 3	57010	0.14
chr7_44467574_44467873	0.61	Josd2	Josephin domain containing 2	257	0.57
chr2_168441196_168441347	0.60	Gm14234	predicted gene 14234	22697	0.2
chrX_146962362_146963776	0.60	Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	46	0.97
chr11_78034745_78034901	0.60	Dhrs13os	dehydrogenase/reductase (SDR family) member 13, opposite strand	2158	0.14
chr6_88519047_88519558	0.60	Gm44430	predicted gene, 44430	289	0.58
chr8_64691882_64692436	0.60	Cpe	carboxypeptidase E	895	0.57
chr19_6995553_6996110	0.58	Nudt22	nudix (nucleoside diphosphate linked moiety X)-type motif 22	206	0.56
chr8_66697150_66698637	0.58	Npy1r	neuropeptide Y receptor Y1	471	0.82
chr10_115251625_115252192	0.58	Tbc1d15	TBC1 domain family, member 15	441	0.82
chr5_129908865_129909017	0.58	Nupr1l	nuclear protein transcriptional regulator 1 like	373	0.74
chr5_111256050_111256270	0.58	Ttc28	tetratricopeptide repeat domain 28	20845	0.18
chr6_122669328_122669812	0.57	Gm10420	predicted gene 10420	26431	0.1
chr6_126938580_126939554	0.56	Rad51ap1	RAD51 associated protein 1	479	0.58
chr17_24205669_24205953	0.56	Tbc1d24	TBC1 domain family, member 24	249	0.8
chr4_143298537_143299593	0.55	Pdpn	podoplanin	398	0.83
chr2_91119045_91119896	0.55	Mybpc3	myosin binding protein C, cardiac	1326	0.3
chr15_68931535_68932379	0.55	Khdrbs3	KH domain containing, RNA binding, signal transduction associated 3	1889	0.38
chr3_123448089_123448441	0.55	Gm35065	predicted gene, 35065	818	0.45
chr1_79450112_79451070	0.55	Scg2	secretogranin II	10471	0.24
chr16_63863108_63864179	0.54	Epha3	Eph receptor A3	230	0.96
chr5_24365983_24366141	0.54	Nos3	nitric oxide synthase 3, endothelial cell	1252	0.26
chr6_119669819_119669970	0.53	Erc1	ELKS/RAB6-interacting/CAST family member 1	47789	0.16
chr13_36283360_36283511	0.52	Gm48766	predicted gene, 48766	31076	0.17
chr9_96889529_96889927	0.52	Pxylp1	2-phosphoxylose phosphatase 1	254	0.9
chr18_54125378_54126373	0.52	Gm8594	predicted gene 8594	94567	0.09
chr10_127259299_127259459	0.52	Kif5a	kinesin family member 5A	3701	0.09
chr17_64602299_64602450	0.51	Man2a1	mannosidase 2, alpha 1	1638	0.47
chr5_84281287_84281877	0.51	Epha5	Eph receptor A5	80484	0.11
chr18_20609699_20610303	0.51	Dsg2	desmoglein 2	51755	0.1
chr10_29535419_29536227	0.51	Rspo3	R-spondin 3	44	0.96
chr15_64177808_64178416	0.51	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	30379	0.19
chr7_80339234_80339763	0.50	Unc45a	unc-45 myosin chaperone A	68	0.94
chr9_75541655_75541806	0.50	Tmod3	tropomodulin 3	23	0.97
chr6_145481872_145482220	0.50	Gm25373	predicted gene, 25373	17857	0.16
chr4_32916089_32916240	0.50	Ankrd6	ankyrin repeat domain 6	7291	0.17
chr11_87447972_87448598	0.50	Rnu3b3	U3B small nuclear RNA 3	342	0.74
chr10_34299043_34301066	0.50	Tspyl4	TSPY-like 4	798	0.4
chr3_38886705_38888202	0.50	Fat4	FAT atypical cadherin 4	513	0.62
chr1_175625783_175626003	0.49	Fh1	fumarate hydratase 1	258	0.91
chr9_30918491_30920140	0.48	Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	1635	0.4
chrX_168779063_168779495	0.48	Gm15233	predicted gene 15233	4023	0.27
chr11_69412589_69413874	0.48	Kdm6b	KDM1 lysine (K)-specific demethylase 6B	444	0.64
chr14_54959915_54960463	0.48	Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	2282	0.1
chr16_4267685_4268655	0.48	Gm5766	predicted gene 5766	37869	0.13
chr8_33711249_33711400	0.47	Gm24727	predicted gene, 24727	19523	0.12
chr14_67229549_67230710	0.47	Gm20675	predicted gene 20675	3000	0.21
chr6_83038262_83039190	0.47	Loxl3	lysyl oxidase-like 3	326	0.68
chr8_106717968_106718245	0.47	Tango6	transport and golgi organization 6	34960	0.16
chr5_134746440_134747928	0.47	Eln	elastin	62	0.61
chr2_69586896_69588383	0.46	Lrp2	low density lipoprotein receptor-related protein 2	1574	0.42
chr14_101532225_101532447	0.46	Tbc1d4	TBC1 domain family, member 4	25010	0.19
chr13_71458632_71459335	0.45	1700112M02Rik	RIKEN cDNA 1700112M02 gene	28624	0.25
chr19_16872320_16872916	0.45	Foxb2	forkhead box B2	1187	0.41
chr16_74404583_74404887	0.45	Robo2	roundabout guidance receptor 2	6177	0.28
chr6_90763313_90763904	0.45	Iqsec1	IQ motif and Sec7 domain 1	533	0.77
chr13_92530321_92530813	0.44	Zfyve16	zinc finger, FYVE domain containing 16	301	0.91
chr2_135439627_135440202	0.44	9630028H03Rik	RIKEN cDNA 9630028H03 gene	143382	0.04
chr2_137115145_137115830	0.44	Jag1	jagged 1	1157	0.62
chr17_57769126_57770140	0.44	Cntnap5c	contactin associated protein-like 5C	63	0.97
chr2_152636550_152636849	0.44	Rem1	rad and gem related GTP binding protein 1	3732	0.1
chr7_79466586_79467287	0.43	Gm10616	predicted gene 10616	527	0.42
chr13_69481908_69482542	0.43	Gm48676	predicted gene, 48676	31775	0.13
chr4_134102645_134103058	0.43	Ubxn11	UBX domain protein 11	232	0.87
chr2_166359933_166360116	0.43	Gm14268	predicted gene 14268	38133	0.16
chr8_54239099_54239565	0.42	Vegfc	vascular endothelial growth factor C	161553	0.04
chr12_27334769_27335068	0.42	Sox11	SRY (sex determining region Y)-box 11	7656	0.29
chrX_94212994_94213232	0.42	Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked	251	0.91
chr7_130260560_130262022	0.42	Fgfr2	fibroblast growth factor receptor 2	566	0.84
chr15_23035608_23036941	0.42	Cdh18	cadherin 18	181	0.97
chr2_26442534_26442685	0.41	Sec16a	SEC16 homolog A, endoplasmic reticulum export factor	2591	0.13
chr17_57148993_57149872	0.41	Cd70	CD70 antigen	345	0.79
chr8_11314471_11315722	0.41	Col4a1	collagen, type IV, alpha 1	2270	0.23
chr2_4154106_4154733	0.41	Frmd4a	FERM domain containing 4A	1547	0.26
chr15_98093657_98093849	0.41	Senp1	SUMO1/sentrin specific peptidase 1	9	0.87
chr7_109438401_109439524	0.40	Stk33	serine/threonine kinase 33	36	0.83
chr9_77344436_77344707	0.40	Mlip	muscular LMNA-interacting protein	3222	0.21
chr16_34744940_34746455	0.40	Mylk	myosin, light polypeptide kinase	487	0.85
chr4_124575007_124576219	0.40	4933407E24Rik	RIKEN cDNA 4933407E24 gene	6423	0.2
chr12_33027311_33027589	0.40	Cdhr3	cadherin-related family member 3	25536	0.12
chr4_134245643_134245910	0.40	Zfp593	zinc finger protein 593	184	0.83
chr17_72925143_72925481	0.39	Lbh	limb-bud and heart	4124	0.28
chr2_90474974_90475432	0.39	Ptprj	protein tyrosine phosphatase, receptor type, J	3867	0.21
chr12_37880304_37881575	0.39	Dgkb	diacylglycerol kinase, beta	223	0.96
chr17_45506891_45507081	0.39	Aars2	alanyl-tRNA synthetase 2, mitochondrial	145	0.92
chr2_60722236_60722934	0.39	Itgb6	integrin beta 6	58	0.98
chr4_66404373_66404645	0.38	Astn2	astrotactin 2	26	0.99
chr12_89812406_89813090	0.38	Nrxn3	neurexin III	265	0.96
chr9_104062615_104063123	0.38	Uba5	ubiquitin-like modifier activating enzyme 5	36	0.88
chr6_135011636_135012016	0.38	Ddx47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	173	0.94
chr11_23067183_23067334	0.37	Gm12059	predicted gene 12059	740	0.6
chr14_108909943_108910203	0.37	Slitrk1	SLIT and NTRK-like family, member 1	4085	0.37
chr11_78163229_78163523	0.37	Traf4	TNF receptor associated factor 4	2140	0.11
chr2_59438620_59439113	0.37	Gm13549	predicted gene 13549	39085	0.13
chr10_117023795_117024543	0.37	Gm10747	predicted gene 10747	19577	0.11
chr2_19344903_19345364	0.36	4930447M23Rik	RIKEN cDNA 4930447M23 gene	196	0.94
chr12_85178232_85178383	0.36	Pgf	placental growth factor	517	0.66
chr8_31150331_31150537	0.36	Tti2	TELO2 interacting protein 2	94	0.85
chr1_153652756_153654124	0.36	Rgs8	regulator of G-protein signaling 8	415	0.8
chr6_143100273_143100480	0.36	C2cd5	C2 calcium-dependent domain containing 5	235	0.92
chr8_22506948_22507557	0.36	Slc20a2	solute carrier family 20, member 2	1026	0.46
chrX_161907356_161907507	0.36	Gm15202	predicted gene 15202	792	0.75
chr8_121382840_121383267	0.35	Gm26815	predicted gene, 26815	26217	0.16
chr9_7176368_7177410	0.35	Dync2h1	dynein cytoplasmic 2 heavy chain 1	68	0.98
chr5_92698277_92699272	0.35	Shroom3	shroom family member 3	15149	0.16
chr15_96271638_96271789	0.35	2610037D02Rik	RIKEN cDNA 2610037D02 gene	11895	0.18
chr11_43528323_43528679	0.35	Ccnjl	cyclin J-like	283	0.89
chr17_35867106_35867524	0.35	Ppp1r18os	protein phosphatase 1, regulatory subunit 18, opposite strand	429	0.42
chr19_37877611_37878244	0.34	Gm4757	predicted gene 4757	7657	0.21
chr18_35834043_35834925	0.34	Gm29417	predicted gene 29417	3391	0.13
chr5_90902965_90904167	0.34	Cxcl2	chemokine (C-X-C motif) ligand 2	305	0.84
chr18_47365019_47365190	0.34	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	3164	0.28
chr13_12565430_12565777	0.33	Ero1lb	ERO1-like beta (S. cerevisiae)	271	0.88
chr8_56932747_56932927	0.33	Gm7328	predicted gene 7328	19992	0.23
chr19_7398904_7399138	0.33	Rab11b-ps2	RAB11B, member RAS oncogene family, pseudogene 2	56	0.95
chr6_85332444_85333044	0.33	Sfxn5	sideroflexin 5	6	0.97
chr3_106730147_106730298	0.33	Lrif1	ligand dependent nuclear receptor interacting factor 1	2692	0.25
chr2_73213682_73214373	0.33	Ola1	Obg-like ATPase 1	306	0.89
chr9_96537234_96537629	0.33	Gm8495	predicted gene 8495	270	0.86
chr7_141069915_141071420	0.33	B4galnt4	beta-1,4-N-acetyl-galactosaminyl transferase 4	65	0.93
chr5_135078421_135078620	0.33	Vps37d	vacuolar protein sorting 37D	254	0.82
chr10_76468272_76468799	0.33	Ybey	ybeY metallopeptidase	328	0.51
chr4_128428742_128429295	0.33	Csmd2	CUB and Sushi multiple domains 2	48136	0.16
chr18_10706006_10706729	0.32	Abhd3	abhydrolase domain containing 3	339	0.59
chr4_124570892_124571307	0.32	4933407E24Rik	RIKEN cDNA 4933407E24 gene	1909	0.33
chr1_82586379_82587667	0.32	Col4a3	collagen, type IV, alpha 3	47	0.67
chr18_5333704_5334306	0.32	Zfp438	zinc finger protein 438	408	0.86
chr6_85373595_85374585	0.32	Rab11fip5	RAB11 family interacting protein 5 (class I)	474	0.76
chr12_46814495_46815083	0.31	Nova1	NOVA alternative splicing regulator 1	2171	0.31

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax1_Pax9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2	1.4	GO:0035902	response to immobilization stress(GO:0035902)
0.2	1.6	GO:0042118	endothelial cell activation(GO:0042118)
0.2	1.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.2	0.6	GO:0030070	insulin processing(GO:0030070)
0.2	0.6	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2	0.6	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.2	0.5	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.2	0.7	GO:0006551	leucine metabolic process(GO:0006551)
0.2	1.0	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	0.5	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.2	0.5	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.7	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.1	0.4	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.7	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.1	0.8	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.1	0.5	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	1.5	GO:0007638	mechanosensory behavior(GO:0007638)
0.1	0.3	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.1	1.0	GO:0071625	vocalization behavior(GO:0071625)
0.1	0.9	GO:0019732	antifungal humoral response(GO:0019732)
0.1	0.3	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.4	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1	0.2	GO:1990791	dorsal root ganglion development(GO:1990791)
0.1	0.5	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.9	GO:0002934	desmosome organization(GO:0002934)
0.1	0.3	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.1	0.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.3	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1	0.1	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.1	0.4	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.2	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	1.1	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.6	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.1	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1	0.4	GO:0031034	myosin filament assembly(GO:0031034)
0.1	0.4	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.1	0.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.1	0.2	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.1	0.2	GO:0015755	fructose transport(GO:0015755)
0.1	0.3	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	0.2	GO:0035482	gastric motility(GO:0035482)
0.1	0.3	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.1	0.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.1	0.2	GO:0070375	ERK5 cascade(GO:0070375)
0.1	0.2	GO:0021557	oculomotor nerve development(GO:0021557)
0.1	0.2	GO:0097113	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1	0.3	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.2	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1	0.4	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.1	0.2	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.1	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.5	GO:0030432	peristalsis(GO:0030432)
0.1	0.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	0.1	GO:0030035	microspike assembly(GO:0030035)
0.1	0.3	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1	0.4	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.3	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:2000821	regulation of grooming behavior(GO:2000821)
0.0	0.1	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0	0.4	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.6	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	0.1	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.6	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.7	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.2	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.4	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.2	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	1.2	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.2	GO:0072017	distal tubule development(GO:0072017)
0.0	0.1	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0	0.1	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.8	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.4	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.3	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.0	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.4	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.3	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.2	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.2	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.0	0.0	GO:2000974	negative regulation of pro-B cell differentiation(GO:2000974)
0.0	0.3	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0	0.3	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.1	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.0	0.1	GO:0071435	potassium ion export(GO:0071435)
0.0	0.4	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.2	GO:0061525	hindgut development(GO:0061525)
0.0	0.9	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.0	0.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.2	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.0	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.3	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.4	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.2	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.7	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0090128	regulation of synapse maturation(GO:0090128)
0.0	0.1	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0002086	diaphragm contraction(GO:0002086)
0.0	0.2	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.1	GO:0042851	alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078) L-alanine metabolic process(GO:0042851)
0.0	0.2	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.0	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.0	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.1	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.1	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.0	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.1	GO:0042436	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.0	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.0	0.0	GO:0003166	bundle of His development(GO:0003166)
0.0	0.0	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.3	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.1	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0021559	trigeminal nerve development(GO:0021559)
0.0	0.1	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0	0.0	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.2	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.1	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.1	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.0	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.1	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.1	GO:0070922	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) small RNA loading onto RISC(GO:0070922)
0.0	0.1	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.0	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.0	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.0	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.6	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.3	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.0	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.0	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0033574	response to testosterone(GO:0033574)
0.0	0.0	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.0	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.1	GO:0006862	nucleotide transport(GO:0006862)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.0	0.0	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.2	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.0	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.1	GO:0036065	fucosylation(GO:0036065)
0.0	0.1	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.0	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0005608	laminin-3 complex(GO:0005608)
0.2	1.5	GO:0042788	polysomal ribosome(GO:0042788)
0.2	0.5	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	1.1	GO:0005883	neurofilament(GO:0005883)
0.1	0.8	GO:0005915	zonula adherens(GO:0005915)
0.1	0.8	GO:0032584	growth cone membrane(GO:0032584)
0.1	0.8	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.9	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	0.5	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.3	GO:0071953	elastic fiber(GO:0071953)
0.1	0.4	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.5	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.3	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.4	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.5	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.2	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	1.0	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	1.0	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.5	GO:0031045	dense core granule(GO:0031045)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.7	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.3	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.6	GO:0036379	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	1.3	GO:0014704	intercalated disc(GO:0014704)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	0.8	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.0	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.1	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.9	GO:0043195	terminal bouton(GO:0043195)
0.0	0.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0044393	microspike(GO:0044393)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.3	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.0	GO:0005914	spot adherens junction(GO:0005914)
0.0	0.1	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.3	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.0	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.1	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.3	1.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	1.3	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.1	0.5	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.5	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.1	1.1	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	1.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.4	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.4	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	0.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.8	GO:0046790	virion binding(GO:0046790)
0.1	0.3	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.6	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.1	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.5	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.4	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	0.5	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.4	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.2	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.1	1.3	GO:0000217	DNA secondary structure binding(GO:0000217)
0.1	0.6	GO:0051378	serotonin binding(GO:0051378)
0.1	0.3	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	0.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.3	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.1	0.2	GO:0031433	telethonin binding(GO:0031433)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.8	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.4	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.8	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.2	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0034920	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.2	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0033265	choline binding(GO:0033265)
0.0	1.0	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.3	GO:0043912	D-lysine oxidase activity(GO:0043912)
0.0	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.4	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.9	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.7	GO:0008483	transaminase activity(GO:0008483)
0.0	0.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.2	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	1.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.3	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0010851	cyclase regulator activity(GO:0010851)
0.0	0.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.5	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.6	GO:0016232	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.0	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.0	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	0.0	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	1.1	GO:0005178	integrin binding(GO:0005178)
0.0	0.3	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.2	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.1	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	1.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	1.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.5	PID BMP PATHWAY	BMP receptor signaling
0.0	1.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.5	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.9	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.5	PID FGF PATHWAY	FGF signaling pathway
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.2	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.0	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	1.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.1	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME PLATELET HOMEOSTASIS	Genes involved in Platelet homeostasis
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	1.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	1.8	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors

Results for Pax1_Pax9

Z-value: 0.72

Motif logo

Transcription factors associated with Pax1_Pax9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Pax1_Pax9 motif across conditions

Conditions sorted by the z-value of the Pax1_Pax9 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax1_Pax9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: