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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Phox2a

Z-value: 0.44

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Transcription factors associated with Phox2a

Gene Symbol	Gene ID	Gene Info
Phox2a Ensembl NCBI MGI UniProt	ENSMUSG00000007946.9	Phox2a

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Phox2a	chr7_101817270_101817487	935	0.370259	-0.12	3.6e-01	Click!
Phox2a	chr7_101816943_101817222	1231	0.277841	-0.11	4.1e-01	Click!
Phox2a	chr7_101819111_101819732	1108	0.305302	-0.11	4.2e-01	Click!
Phox2a	chr7_101819812_101819963	859	0.396288	0.07	5.9e-01	Click!
Phox2a	chr7_101820668_101822582	879	0.377239	0.06	6.5e-01	Click!

Activity of the Phox2a motif across conditions

Conditions sorted by the z-value of the Phox2a motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_63249784_63250324	1.23	Gata4	GATA binding protein 4	4783	0.2
chr13_96986050_96986201	0.87	Gm48609	predicted gene, 48609	29174	0.13
chr13_73262153_73264451	0.86	Irx4	Iroquois homeobox 4	2805	0.22
chr14_111166555_111166800	0.79	Gm22802	predicted gene, 22802	115369	0.07
chr10_33083500_33083959	0.76	Trdn	triadin	168	0.97
chr2_155611238_155612364	0.75	Myh7b	myosin, heavy chain 7B, cardiac muscle, beta	589	0.53
chr13_12132755_12132906	0.69	Ryr2	ryanodine receptor 2, cardiac	25885	0.13
chr5_138608490_138608879	0.65	Zfp68	zinc finger protein 68	1627	0.2
chr7_103809605_103809899	0.65	Hbb-bt	hemoglobin, beta adult t chain	4244	0.07
chr17_71290536_71290920	0.64	Emilin2	elastin microfibril interfacer 2	6519	0.15
chr2_154631717_154631891	0.64	Gm14198	predicted gene 14198	832	0.46
chr14_32684282_32684433	0.63	3425401B19Rik	RIKEN cDNA 3425401B19 gene	915	0.46
chr16_96205810_96206739	0.60	Sh3bgr	SH3-binding domain glutamic acid-rich protein	369	0.83
chr17_85485071_85487191	0.57	Rpl31-ps16	ribosomal protein L31, pseudogene 16	12502	0.23
chr7_136275874_136276030	0.55	C030029H02Rik	RIKEN cDNA C030029H02 gene	7618	0.21
chr10_40135263_40135524	0.54	Slc16a10	solute carrier family 16 (monocarboxylic acid transporters), member 10	6861	0.14
chr3_134236641_134237783	0.54	Cxxc4	CXXC finger 4	392	0.78
chr13_7239804_7239955	0.51	Gm40663	predicted gene, 40663	63954	0.12
chr16_20594716_20594867	0.50	Vwa5b2	von Willebrand factor A domain containing 5B2	3635	0.07
chr19_53794096_53794765	0.50	Rbm20	RNA binding motif protein 20	1122	0.48
chr19_28037121_28037467	0.49	Gm5517	predicted gene 5517	3830	0.23
chr5_138609015_138609166	0.49	Gm15497	predicted gene 15497	1649	0.2
chrX_142684293_142684706	0.48	Tmem164	transmembrane protein 164	1611	0.4
chr5_64807638_64809344	0.48	Klf3	Kruppel-like factor 3 (basic)	3848	0.17
chr4_149990023_149990174	0.47	H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	11167	0.15
chr4_123563270_123563441	0.47	Macf1	microtubule-actin crosslinking factor 1	1339	0.45
chr4_84637359_84638298	0.46	Bnc2	basonuclin 2	37168	0.19
chr3_149088208_149089249	0.46	Gm25127	predicted gene, 25127	59796	0.12
chr4_137863933_137864084	0.46	Ece1	endothelin converting enzyme 1	1711	0.38
chr11_117059965_117061040	0.46	Gm11731	predicted gene 11731	2077	0.18
chr4_116073957_116074118	0.44	Uqcrh	ubiquinol-cytochrome c reductase hinge protein	994	0.31
chr3_95740644_95740875	0.43	Ecm1	extracellular matrix protein 1	1190	0.25
chr18_68228785_68229512	0.43	Ldlrad4	low density lipoprotein receptor class A domain containing 4	1081	0.51
chr11_88840326_88840785	0.43	Akap1	A kinase (PRKA) anchor protein 1	985	0.51
chr6_118759013_118759164	0.43	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	1114	0.62
chr15_11741805_11742688	0.42	Gm41271	predicted gene, 41271	38543	0.18
chr15_5555660_5555811	0.42	5430437J10Rik	RIKEN cDNA 5430437J10 gene	24477	0.23
chr5_116456914_116457389	0.42	Gm42853	predicted gene 42853	333	0.83
chr14_99366007_99366683	0.41	Gm49218	predicted gene, 49218	328	0.85
chr13_83522624_83522907	0.41	Mef2c	myocyte enhancer factor 2C	708	0.79
chr17_47909108_47910390	0.41	Gm15556	predicted gene 15556	12629	0.13
chr3_53730067_53730769	0.41	Gm30735	predicted gene, 30735	4941	0.16
chr3_63899898_63900049	0.41	Plch1	phospholipase C, eta 1	501	0.73
chr4_134514105_134514256	0.40	Aunip	aurora kinase A and ninein interacting protein	3181	0.14
chrX_138915472_138915880	0.40	Nrk	Nik related kinase	1245	0.61
chr1_131232374_131233673	0.40	Rassf5	Ras association (RalGDS/AF-6) domain family member 5	552	0.67
chrX_114816407_114816558	0.40	Gm14897	predicted gene 14897	41405	0.14
chr5_65900728_65900879	0.39	Gm43769	predicted gene 43769	10821	0.11
chr3_122243418_122243576	0.38	Gclm	glutamate-cysteine ligase, modifier subunit	2060	0.17
chr18_64492934_64493085	0.37	Fech	ferrochelatase	2758	0.22
chr14_30530906_30531057	0.37	Dcp1a	decapping mRNA 1A	7274	0.15
chr10_42634471_42634622	0.37	Ostm1	osteopetrosis associated transmembrane protein 1	44370	0.13
chr9_103364095_103364246	0.37	Cdv3	carnitine deficiency-associated gene expressed in ventricle 3	727	0.6
chr3_155052033_155052416	0.37	Tnni3k	TNNI3 interacting kinase	3126	0.26
chr2_155894612_155894870	0.37	Uqcc1	ubiquinol-cytochrome c reductase complex assembly factor 1	15863	0.12
chr4_132513569_132513723	0.36	Sesn2	sestrin 2	3145	0.12
chr4_123990305_123991528	0.36	Gm12902	predicted gene 12902	64682	0.08
chr1_135840170_135841177	0.35	Tnnt2	troponin T2, cardiac	26	0.97
chr5_106463547_106465134	0.35	Barhl2	BarH like homeobox 2	6174	0.18
chr11_61142924_61143667	0.35	Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	630	0.65
chr19_6919975_6920251	0.34	Esrra	estrogen related receptor, alpha	938	0.29
chr2_132427542_132428080	0.34	4921508D12Rik	RIKEN cDNA 4921508D12 gene	3070	0.25
chr15_89168947_89170050	0.34	Plxnb2	plexin B2	1190	0.27
chr1_135715343_135715494	0.33	Csrp1	cysteine and glycine-rich protein 1	4643	0.19
chr6_14754259_14754642	0.33	Ppp1r3a	protein phosphatase 1, regulatory subunit 3A	824	0.77
chrX_164437518_164437860	0.33	Asb11	ankyrin repeat and SOCS box-containing 11	369	0.85
chr13_37859653_37859927	0.32	Rreb1	ras responsive element binding protein 1	1856	0.37
chr8_27263249_27263470	0.32	Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	1055	0.37
chr8_39011566_39011717	0.32	Tusc3	tumor suppressor candidate 3	5731	0.26
chr5_76778953_76779779	0.32	C530008M17Rik	RIKEN cDNA C530008M17 gene	26998	0.16
chr3_35332632_35333522	0.32	Gm25442	predicted gene, 25442	7463	0.26
chr16_96202794_96202945	0.32	Sh3bgr	SH3-binding domain glutamic acid-rich protein	2140	0.24
chr14_20918784_20918935	0.32	Vcl	vinculin	10539	0.2
chr18_54719777_54720132	0.32	Gm5821	predicted gene 5821	46178	0.16
chr4_44663567_44664953	0.32	Gm12462	predicted gene 12462	155	0.94
chr10_95297621_95297998	0.31	Gm48880	predicted gene, 48880	17044	0.14
chr1_184675496_184676152	0.31	Gm38358	predicted gene, 38358	19210	0.14
chr1_56974277_56974569	0.31	Satb2	special AT-rich sequence binding protein 2	1921	0.24
chr17_30187860_30188415	0.31	Zfand3	zinc finger, AN1-type domain 3	9439	0.17
chr9_64918332_64919221	0.30	Dennd4a	DENN/MADD domain containing 4A	6293	0.16
chr2_38784133_38784675	0.30	Nr6a1	nuclear receptor subfamily 6, group A, member 1	65	0.95
chr12_91383730_91384393	0.30	Cep128	centrosomal protein 128	292	0.68
chr16_4519120_4519560	0.30	Srl	sarcalumenin	3723	0.19
chr11_64656679_64656830	0.30	Gm24275	predicted gene, 24275	66114	0.13
chr5_121184834_121185467	0.30	Gm42930	predicted gene 42930	154	0.93
chr8_116919844_116920132	0.30	Cmc2	COX assembly mitochondrial protein 2	1377	0.33
chrX_103472886_103473037	0.30	Xist	inactive X specific transcripts	5705	0.09
chr14_69279140_69279312	0.30	Gm20236	predicted gene, 20236	2914	0.13
chr12_69195806_69195957	0.30	Gm49383	predicted gene, 49383	1223	0.17
chr11_99243687_99244404	0.29	Krt222	keratin 222	22	0.97
chr12_100242288_100242784	0.29	Gm40557	predicted gene, 40557	92	0.96
chr6_87422198_87422649	0.29	Bmp10	bone morphogenetic protein 10	6571	0.15
chr13_30338441_30338963	0.29	Agtr1a	angiotensin II receptor, type 1a	2258	0.33
chr8_46216441_46216738	0.29	Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4	5305	0.12
chr12_49387532_49388566	0.29	3110039M20Rik	RIKEN cDNA 3110039M20 gene	1603	0.26
chr11_62629548_62630855	0.29	Lrrc75aos1	leucine rich repeat containing 75A, opposite strand 1	4503	0.09
chr8_127552716_127553166	0.29	Gm6921	predicted pseudogene 6921	8494	0.23
chr15_101191724_101192125	0.29	Mir6962	microRNA 6962	1945	0.2
chr4_107004970_107005270	0.29	Gm12786	predicted gene 12786	17379	0.15
chr18_69608508_69609200	0.29	Tcf4	transcription factor 4	3590	0.33
chr3_58419356_58419775	0.28	Tsc22d2	TSC22 domain family, member 2	2081	0.31
chr19_28580015_28580320	0.28	4933413C19Rik	RIKEN cDNA 4933413C19 gene	3127	0.3
chr2_63982565_63982778	0.28	Fign	fidgetin	115317	0.07
chr12_117743931_117744082	0.28	Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5	3411	0.26
chr2_93008102_93008253	0.28	Prdm11	PR domain containing 11	5733	0.21
chr15_77202946_77203567	0.28	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	180	0.94
chr4_109677685_109677836	0.28	Faf1	Fas-associated factor 1	763	0.61
chr5_106705019_106705272	0.28	Zfp644	zinc finger protein 644	7858	0.14
chr1_155526845_155527426	0.27	Gm5532	predicted gene 5532	8	0.98
chr15_40661942_40662224	0.27	Zfpm2	zinc finger protein, multitype 2	2907	0.38
chr1_139459017_139459540	0.27	Aspm	abnormal spindle microtubule assembly	4459	0.2
chrX_10992282_10993226	0.27	Gm14485	predicted gene 14485	28253	0.23
chr7_109191327_109192334	0.27	Lmo1	LIM domain only 1	16623	0.17
chr10_37988715_37989307	0.27	Gm24710	predicted gene, 24710	57331	0.15
chr5_106757360_106758250	0.26	Gm8365	predicted gene 8365	19041	0.17
chr1_190928081_190928453	0.26	Angel2	angel homolog 2	225	0.91
chr15_40115274_40115425	0.26	9330182O14Rik	RIKEN cDNA 9330182O14 gene	19016	0.17
chr4_151083338_151083489	0.26	Camta1	calmodulin binding transcription activator 1	3620	0.2
chr8_106890881_106891378	0.26	Chtf8	CTF8, chromosome transmission fidelity factor 8	2086	0.18
chr5_99970736_99971131	0.25	Hnrnpd	heterogeneous nuclear ribonucleoprotein D	4546	0.16
chr2_133739629_133739780	0.25	Gm25258	predicted gene, 25258	155283	0.04
chr6_86683779_86684487	0.25	Snrnp27	small nuclear ribonucleoprotein 27 (U4/U6.U5)	358	0.77
chrY_3871382_3871533	0.25	Gm18177	predicted gene, 18177	4471	0.13
chr5_75083070_75083610	0.25	Gsx2	GS homeobox 2	7738	0.12
chr15_85463399_85463550	0.25	7530416G11Rik	RIKEN cDNA 7530416G11 gene	39753	0.14
chr15_9529382_9529634	0.25	Il7r	interleukin 7 receptor	258	0.94
chr18_42252337_42252647	0.25	Rps19-ps4	ribosomal protein S19, pseudogene 4	94	0.95
chr12_101978605_101978756	0.25	Ndufb1-ps	NADH:ubiquinone oxidoreductase subunit B1	1612	0.3
chr3_135421547_135421698	0.25	Cisd2	CDGSH iron sulfur domain 2	1457	0.26
chr17_40811481_40812037	0.25	Rhag	Rhesus blood group-associated A glycoprotein	575	0.7
chr4_131844041_131844267	0.24	Mecr	mitochondrial trans-2-enoyl-CoA reductase	649	0.61
chr17_10293681_10293832	0.24	Qk	quaking	10823	0.25
chr17_14959778_14960235	0.24	Phf10	PHD finger protein 10	479	0.69
chr11_117414820_117416356	0.24	Gm11729	predicted gene 11729	1199	0.39
chr12_56298063_56298592	0.24	Gm47682	predicted gene, 47682	43929	0.1
chr2_119619277_119620230	0.24	Nusap1	nucleolar and spindle associated protein 1	1024	0.3
chr16_23780715_23780866	0.24	Gm49515	predicted gene, 49515	663	0.75
chr18_56715299_56715450	0.24	Lmnb1	lamin B1	7561	0.19
chr19_34165708_34165981	0.24	Ankrd22	ankyrin repeat domain 22	209	0.93
chr8_81856300_81856587	0.23	Inpp4b	inositol polyphosphate-4-phosphatase, type II	75	0.98
chr9_77344708_77344864	0.23	Mlip	muscular LMNA-interacting protein	3007	0.22
chr7_69891593_69891960	0.23	Gm44690	predicted gene 44690	7416	0.25
chr3_9573681_9573832	0.23	Zfp704	zinc finger protein 704	8457	0.25
chr8_33916300_33917561	0.23	Rbpms	RNA binding protein gene with multiple splicing	12346	0.17
chr16_92478627_92479097	0.23	2410124H12Rik	RIKEN cDNA 2410124H12 gene	120	0.95
chr13_76999543_76999694	0.23	Slf1	SMC5-SMC6 complex localization factor 1	47779	0.16
chr4_40851422_40852119	0.23	Gm25931	predicted gene, 25931	1368	0.21
chrX_143825863_143827628	0.23	Capn6	calpain 6	587	0.46
chr14_47299300_47299451	0.23	Mapk1ip1l	mitogen-activated protein kinase 1 interacting protein 1-like	604	0.41
chr8_48596222_48596652	0.23	Gm45772	predicted gene 45772	34732	0.19
chr12_9253584_9253735	0.23	Gm46323	predicted gene, 46323	117779	0.06
chr1_127676820_127678197	0.23	Tmem163	transmembrane protein 163	513	0.83
chr7_113249773_113249924	0.23	Arntl	aryl hydrocarbon receptor nuclear translocator-like	10094	0.2
chr12_84589686_84590923	0.23	Abcd4	ATP-binding cassette, sub-family D (ALD), member 4	13748	0.15
chr2_58509453_58510324	0.23	Acvr1	activin A receptor, type 1	6384	0.23
chr16_33060324_33060635	0.22	Lmln	leishmanolysin-like (metallopeptidase M8 family)	2042	0.19
chr8_119490510_119491264	0.22	Slc38a8	solute carrier family 38, member 8	4008	0.17
chr7_6281481_6281771	0.22	Gm45069	predicted gene 45069	1984	0.19
chr17_44136324_44136532	0.22	Clic5	chloride intracellular channel 5	1660	0.43
chr6_24599678_24600100	0.22	Lmod2	leiomodin 2 (cardiac)	2127	0.25
chr13_12033129_12034063	0.22	Gm47493	predicted gene, 47493	18459	0.21
chr6_145276027_145276999	0.22	Rps25-ps1	ribosomal protein S25, pseudogene 1	10113	0.1
chrX_16816049_16816282	0.22	Maob	monoamine oxidase B	1110	0.65
chr10_42613700_42614446	0.22	Ostm1	osteopetrosis associated transmembrane protein 1	30235	0.16
chr3_21935032_21935297	0.22	Gm43674	predicted gene 43674	63304	0.12
chr13_94595583_94596884	0.22	Gm36991	predicted gene, 36991	23047	0.16
chr2_31692679_31692830	0.22	Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	3143	0.14
chr3_70104094_70104909	0.22	Gm37585	predicted gene, 37585	12031	0.22
chr3_66982218_66983084	0.22	Shox2	short stature homeobox 2	880	0.47
chr7_75781306_75781612	0.21	AU020206	expressed sequence AU020206	640	0.66
chr12_50111378_50111869	0.21	Gm40418	predicted gene, 40418	8686	0.33
chr2_20966839_20967346	0.21	Arhgap21	Rho GTPase activating protein 21	628	0.68
chr10_61413178_61413819	0.21	Nodal	nodal	4474	0.13
chr6_45096373_45096524	0.21	Gm43879	predicted gene, 43879	15702	0.16
chr10_31386394_31386545	0.21	Gm48094	predicted gene, 48094	12454	0.13
chr9_72791334_72791686	0.21	Gm27204	predicted gene 27204	15285	0.11
chr6_5392568_5392891	0.21	Asb4	ankyrin repeat and SOCS box-containing 4	2302	0.38
chr10_122388056_122388209	0.21	Gm36041	predicted gene, 36041	1240	0.53
chr10_121625316_121626404	0.21	Xpot	exportin, tRNA (nuclear export receptor for tRNAs)	456	0.76
chr12_69157543_69157739	0.21	Rps29	ribosomal protein S29	1413	0.15
chr9_25150579_25151803	0.21	Herpud2	HERPUD family member 2	507	0.62
chr3_53465387_53466092	0.21	Proser1	proline and serine rich 1	1807	0.22
chr14_54362334_54362485	0.21	Oxa1l	oxidase assembly 1-like	1364	0.25
chr9_87406338_87406888	0.21	Gm9540	predicted gene 9540	12363	0.26
chr9_67261068_67261449	0.21	Tln2	talin 2	835	0.67
chr15_80784467_80785284	0.21	Tnrc6b	trinucleotide repeat containing 6b	13767	0.2
chr17_23541898_23542685	0.21	6330415G19Rik	RIKEN cDNA 6330415G19 gene	8508	0.09
chr15_40656769_40657228	0.21	Zfpm2	zinc finger protein, multitype 2	1647	0.51
chr3_69008816_69009141	0.20	Mir15b	microRNA 15b	794	0.37
chr6_18849259_18849471	0.20	Lsm8	LSM8 homolog, U6 small nuclear RNA associated	697	0.51
chr7_109115172_109115418	0.20	Gm44781	predicted gene 44781	27592	0.13
chr15_25773704_25775483	0.20	Myo10	myosin X	606	0.78
chr4_145585026_145585604	0.20	Gm13212	predicted gene 13212	112	0.93
chr16_30236013_30236491	0.20	Gm49645	predicted gene, 49645	18900	0.13
chr3_59028229_59029161	0.20	Med12l	mediator complex subunit 12-like	21717	0.13
chr5_103424052_103424207	0.20	Ptpn13	protein tyrosine phosphatase, non-receptor type 13	1063	0.56
chr14_45330987_45331140	0.20	Psmc6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	308	0.85
chr18_58206037_58206198	0.20	Fbn2	fibrillin 2	3809	0.3
chr2_6719607_6719924	0.20	Celf2	CUGBP, Elav-like family member 2	1848	0.48
chr10_92439233_92439384	0.20	4930401A07Rik	RIKEN cDNA 4930401A07 gene	38294	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Phox2a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.1	0.4	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.1	0.5	GO:0003186	tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
0.1	0.4	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.3	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.2	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.1	0.2	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0	0.2	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.2	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.2	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.2	GO:0035912	dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0	0.2	GO:0051031	tRNA transport(GO:0051031)
0.0	0.2	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.2	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.2	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.1	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.1	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0	0.1	GO:0060137	maternal process involved in parturition(GO:0060137)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.0	0.1	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.1	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.1	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.3	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.0	GO:0045472	response to ether(GO:0045472)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.0	0.1	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.1	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.3	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.0	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0	0.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0071233	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.1	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.1	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.1	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.1	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.0	GO:0010635	regulation of mitochondrial fusion(GO:0010635)
0.0	0.0	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.0	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.1	GO:0035811	negative regulation of urine volume(GO:0035811)
0.0	0.0	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.0	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.0	0.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.1	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0021764	amygdala development(GO:0021764)
0.0	0.0	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0	0.0	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:0060058	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.1	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.0	0.0	GO:0003383	apical constriction(GO:0003383)
0.0	0.0	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.1	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.1	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.0	GO:0019659	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.0	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.1	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.1	GO:0060179	male mating behavior(GO:0060179)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.0	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.0	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.0	GO:0032345	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.2	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.1	GO:0009642	response to light intensity(GO:0009642)
0.0	0.0	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.0	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0070384	Harderian gland development(GO:0070384)
0.0	0.1	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:0060379	cardiac muscle cell myoblast differentiation(GO:0060379)
0.0	0.0	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.0	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	0.4	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.4	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.4	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0032437	cuticular plate(GO:0032437)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.1	GO:0090543	Flemming body(GO:0090543)
0.0	0.0	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.0	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.4	GO:0015030	Cajal body(GO:0015030)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.0	GO:0097441	basilar dendrite(GO:0097441)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0030172	troponin C binding(GO:0030172)
0.1	0.4	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.1	0.6	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	0.2	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.2	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.1	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.2	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.1	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0070694	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.0	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.0	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.1	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
0.0	0.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0070728	leucine binding(GO:0070728)
0.0	0.0	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.0	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	0.1	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events