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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Pou3f3

Z-value: 0.64

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Transcription factors associated with Pou3f3

Gene Symbol	Gene ID	Gene Info
Pou3f3 Ensembl NCBI MGI UniProt	ENSMUSG00000045515.2	POU domain, class 3, transcription factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_42697532_42698715	Pou3f3	2355	0.196721	-0.64	4.6e-08	Click!
chr1_42697110_42697488	Pou3f3	1531	0.264822	-0.63	7.4e-08	Click!
chr1_42700192_42700666	Pou3f3	4661	0.149136	-0.62	1.1e-07	Click!
chr1_42696247_42696979	Pou3f3	845	0.427903	-0.62	1.2e-07	Click!
chr1_42698766_42699058	Pou3f3	3144	0.170054	-0.62	1.2e-07	Click!

Activity of the Pou3f3 motif across conditions

Conditions sorted by the z-value of the Pou3f3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_105520039_105521535	2.32	Atp2c1	ATPase, Ca++-sequestering	360	0.86
chr6_56902400_56902551	1.97	Nt5c3	5'-nucleotidase, cytosolic III	589	0.65
chr5_64804894_64805685	1.88	Gm20033	predicted gene, 20033	1172	0.29
chr6_87431322_87431643	1.74	Bmp10	bone morphogenetic protein 10	2488	0.22
chr17_40813775_40814352	1.68	Rhag	Rhesus blood group-associated A glycoprotein	2879	0.21
chr10_5595752_5595964	1.63	Myct1	myc target 1	2083	0.37
chr8_121088119_121090419	1.61	Gm27530	predicted gene, 27530	4563	0.13
chr2_76981039_76981308	1.58	Ttn	titin	991	0.63
chr3_153850873_153851145	1.54	Asb17os	ankyrin repeat and SOCS box-containing 17, opposite strand	1392	0.25
chrX_106135756_106136481	1.53	Tlr13	toll-like receptor 13	7086	0.16
chr8_70765697_70766944	1.47	6330537M06Rik	RIKEN cDNA 6330537M06 gene	259	0.52
chr8_57320946_57324000	1.46	Hand2os1	Hand2, opposite strand 1	1245	0.3
chr5_75975825_75977229	1.45	Kdr	kinase insert domain protein receptor	1931	0.31
chr14_87140021_87140177	1.41	Diaph3	diaphanous related formin 3	1044	0.58
chr15_36280712_36280964	1.38	Rnf19a	ring finger protein 19A	2260	0.2
chr18_47154125_47154960	1.37	Gm25036	predicted gene, 25036	169	0.69
chr3_152198770_152199020	1.36	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	5050	0.14
chr2_61655339_61656639	1.35	Tank	TRAF family member-associated Nf-kappa B activator	12158	0.22
chr2_121036316_121036674	1.35	Epb42	erythrocyte membrane protein band 4.2	186	0.9
chr13_95614604_95615601	1.29	F2r	coagulation factor II (thrombin) receptor	3385	0.21
chr19_53679305_53679727	1.28	Rbm20	RNA binding motif protein 20	2210	0.3
chr10_93142285_93142436	1.25	Cdk17	cyclin-dependent kinase 17	18515	0.17
chr3_152477886_152478987	1.22	Ak5	adenylate kinase 5	79	0.97
chr11_115902553_115902894	1.21	Smim5	small integral membrane protein 5	2521	0.13
chr9_72037067_72037253	1.20	Gm27450	predicted gene, 27450	3962	0.12
chr6_84328538_84328707	1.17	Gm10445	predicted gene 10445	95216	0.07
chr6_120819964_120820819	1.15	Atp6v1e1	ATPase, H+ transporting, lysosomal V1 subunit E1	1992	0.25
chr3_69007125_69007593	1.14	Smc4	structural maintenance of chromosomes 4	2344	0.15
chr14_79515651_79516545	1.10	Elf1	E74-like factor 1	400	0.83
chr7_120864970_120865460	1.10	Gm15774	predicted gene 15774	10083	0.13
chr11_65740173_65740324	1.09	Mir744	microRNA 744	5416	0.23
chr10_43451894_43452914	1.08	Gm3699	predicted gene 3699	4097	0.17
chr16_77019271_77019422	1.07	Usp25	ubiquitin specific peptidase 25	5559	0.23
chr6_134931016_134931636	1.06	Gm44238	predicted gene, 44238	1214	0.3
chr13_21720851_21721002	1.06	Gm44357	predicted gene, 44357	507	0.36
chr17_70750830_70751314	1.04	5031415H12Rik	RIKEN cDNA 5031415H12 gene	4510	0.21
chr18_65392658_65392927	1.02	Alpk2	alpha-kinase 2	1102	0.35
chr15_6715701_6715852	1.02	Rictor	RPTOR independent companion of MTOR, complex 2	7393	0.23
chr10_63457257_63458786	1.01	Ctnna3	catenin (cadherin associated protein), alpha 3	511	0.78
chr6_56901300_56901698	0.99	Nt5c3	5'-nucleotidase, cytosolic III	384	0.8
chr11_20022697_20022979	0.98	Spred2	sprouty-related EVH1 domain containing 2	68268	0.1
chr6_42352822_42353914	0.95	Zyx	zyxin	110	0.92
chr8_33903501_33903945	0.95	Rbpms	RNA binding protein gene with multiple splicing	11959	0.17
chr19_12575704_12576006	0.94	Fam111a	family with sequence similarity 111, member A	2332	0.16
chr14_80007225_80007376	0.93	Olfm4	olfactomedin 4	6998	0.22
chr19_32180962_32181132	0.92	Sgms1	sphingomyelin synthase 1	15381	0.21
chr2_25094719_25095656	0.92	Noxa1	NADPH oxidase activator 1	38	0.94
chr6_86639363_86639543	0.91	Asprv1	aspartic peptidase, retroviral-like 1	11289	0.11
chr10_21228796_21228971	0.90	Gm33728	predicted gene, 33728	23231	0.13
chr10_67187576_67188154	0.88	Jmjd1c	jumonji domain containing 1C	2112	0.35
chr13_21755717_21756139	0.88	H2bc15	H2B clustered histone 15	1805	0.09
chr9_108308444_108308722	0.87	Rhoa	ras homolog family member A	1754	0.15
chr10_94019632_94020408	0.86	Vezt	vezatin, adherens junctions transmembrane protein	703	0.57
chr8_109105027_109105682	0.86	D030068K23Rik	RIKEN cDNA D030068K23 gene	30109	0.23
chr16_18250494_18250771	0.86	Trmt2a	TRM2 tRNA methyltransferase 2A	611	0.46
chr5_73190710_73191316	0.83	Gm42571	predicted gene 42571	596	0.5
chr7_97749255_97749938	0.83	Aqp11	aquaporin 11	11307	0.16
chr17_61423915_61424066	0.83	Gm6174	predicted gene 6174	26680	0.24
chr1_171440527_171440922	0.83	F11r	F11 receptor	3145	0.12
chr10_93144114_93144265	0.83	Cdk17	cyclin-dependent kinase 17	16686	0.18
chr12_57196255_57197620	0.82	Slc25a21	solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21	535	0.8
chr7_3292731_3293965	0.82	Myadm	myeloid-associated differentiation marker	254	0.81
chr2_172255331_172255625	0.82	Mc3r	melanocortin 3 receptor	6986	0.19
chr15_103251933_103252298	0.82	Nfe2	nuclear factor, erythroid derived 2	428	0.71
chrX_141477069_141477220	0.79	Col4a5	collagen, type IV, alpha 5	1734	0.34
chr2_120152582_120152955	0.79	Ehd4	EH-domain containing 4	1694	0.34
chr6_137754563_137755546	0.79	Dera	deoxyribose-phosphate aldolase (putative)	439	0.86
chr7_133114831_133116529	0.78	Ctbp2	C-terminal binding protein 2	2981	0.2
chr19_53187899_53188052	0.77	Add3	adducin 3 (gamma)	6379	0.17
chr16_92475541_92475940	0.76	2410124H12Rik	RIKEN cDNA 2410124H12 gene	3002	0.18
chr10_53344103_53344254	0.75	Gm47644	predicted gene, 47644	56	0.96
chr3_86624754_86624950	0.75	Gm3788	predicted gene 3788	47316	0.14
chr6_113695103_113695254	0.75	Tatdn2	TatD DNase domain containing 2	1872	0.14
chr3_104632268_104633005	0.75	Gm43582	predicted gene 43582	2021	0.18
chrX_107401572_107402207	0.74	Itm2a	integral membrane protein 2A	1487	0.38
chr18_63252759_63252910	0.74	Gm50172	predicted gene, 50172	12256	0.24
chr8_80496570_80496939	0.74	Gypa	glycophorin A	2973	0.3
chr17_66123585_66124600	0.74	Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	479	0.7
chr2_76979769_76980006	0.74	Ttn	titin	295	0.93
chr5_129178354_129178550	0.73	Rps16-ps2	ribosomal protein S16, pseudogene 2	49935	0.15
chr13_23532575_23532783	0.73	H2ac10	H2A clustered histone 10	1227	0.13
chr3_27151304_27151796	0.73	Ect2	ect2 oncogene	2232	0.24
chr14_65838024_65838325	0.73	Ccdc25	coiled-coil domain containing 25	814	0.6
chr18_85908611_85908899	0.72	Gm5824	predicted gene 5824	60026	0.16
chr4_48407474_48407947	0.72	Invs	inversin	25522	0.19
chr3_152191121_152191504	0.72	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	2533	0.19
chr16_32614355_32614506	0.72	Tfrc	transferrin receptor	802	0.55
chr2_77043494_77043645	0.71	Ccdc141	coiled-coil domain containing 141	511	0.83
chr2_152829459_152831273	0.71	Bcl2l1	BCL2-like 1	56	0.96
chr12_4592745_4593903	0.71	Itsn2	intersectin 2	262	0.51
chr11_78074087_78074838	0.71	Mir451b	microRNA 451b	1221	0.18
chr9_44333046_44333670	0.71	Gm48853	predicted gene, 48853	1028	0.19
chr18_32398020_32398307	0.70	Bin1	bridging integrator 1	9471	0.18
chr8_120607791_120608043	0.70	Gm26739	predicted gene, 26739	9365	0.09
chr18_34409435_34410714	0.69	Pkd2l2	polycystic kidney disease 2-like 2	648	0.7
chr1_174175177_174176129	0.69	Spta1	spectrin alpha, erythrocytic 1	2877	0.14
chr3_65954778_65955426	0.69	Ccnl1	cyclin L1	1754	0.22
chr12_117657998_117660727	0.69	Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5	1328	0.51
chr7_141093606_141093757	0.68	Sigirr	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	69	0.93
chr13_59970938_59972210	0.68	Gm48390	predicted gene, 48390	52136	0.09
chr6_119416453_119417745	0.67	Adipor2	adiponectin receptor 2	376	0.88
chr19_16773138_16773688	0.67	Gm9806	predicted gene 9806	7134	0.2
chr5_143819014_143819653	0.66	Eif2ak1	eukaryotic translation initiation factor 2 alpha kinase 1	1386	0.38
chr2_75776376_75777638	0.66	Gm13657	predicted gene 13657	181	0.93
chr15_64310595_64311230	0.65	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	777	0.63
chr1_172698131_172698383	0.63	Crp	C-reactive protein, pentraxin-related	201	0.93
chr18_34538347_34538600	0.63	Wnt8a	wingless-type MMTV integration site family, member 8A	3840	0.17
chr4_59545758_59545909	0.63	Ptbp3	polypyrimidine tract binding protein 3	2904	0.2
chr2_112284251_112285447	0.63	Slc12a6	solute carrier family 12, member 6	272	0.87
chr5_90519272_90519423	0.63	Afm	afamin	398	0.78
chr5_107874374_107875235	0.62	Evi5	ecotropic viral integration site 5	240	0.86
chr8_77681755_77682458	0.62	Gm45714	predicted gene 45714	22415	0.14
chr6_99204059_99205669	0.62	Foxp1	forkhead box P1	41846	0.2
chr15_32288617_32288915	0.62	Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	43663	0.13
chr17_79344596_79344747	0.62	Cdc42ep3	CDC42 effector protein (Rho GTPase binding) 3	8336	0.22
chr13_34340381_34340544	0.62	Slc22a23	solute carrier family 22, member 23	3741	0.22
chr17_36019993_36020160	0.61	H2-T24	histocompatibility 2, T region locus 24	449	0.55
chr8_3568500_3569092	0.61	Rps23rg1	ribosomal protein S23, retrogene 1	798	0.43
chr12_102355233_102355564	0.61	Rin3	Ras and Rab interactor 3	618	0.76
chr2_152185503_152185779	0.60	Rps15a-ps7	ribosomal protein S15A, pseudogene 7	41	0.97
chr1_9745419_9746231	0.59	1700034P13Rik	RIKEN cDNA 1700034P13 gene	1823	0.26
chr7_50105530_50105803	0.57	Nell1	NEL-like 1	7356	0.32
chr15_80798742_80800160	0.57	Tnrc6b	trinucleotide repeat containing 6b	736	0.7
chr3_104640731_104641028	0.57	Gm43581	predicted gene 43581	2115	0.15
chr6_37438936_37439468	0.57	Creb3l2	cAMP responsive element binding protein 3-like 2	2944	0.36
chr14_49064292_49064929	0.57	Ap5m1	adaptor-related protein complex 5, mu 1 subunit	1487	0.3
chr16_21358278_21358638	0.57	Magef1	melanoma antigen family F, 1	25102	0.18
chr17_51426147_51426785	0.56	C330011F03Rik	RIKEN cDNA C330011F03 gene	9372	0.26
chr12_70148710_70149214	0.56	Abhd12b	abhydrolase domain containing 12B	5180	0.17
chr7_90135078_90135428	0.56	Gm45223	predicted gene 45223	2761	0.16
chr4_150519034_150519503	0.56	Rere	arginine glutamic acid dipeptide (RE) repeats	30875	0.18
chr4_42997551_42997896	0.56	Vcp	valosin containing protein	2710	0.15
chr6_135280959_135281110	0.56	Gm36640	predicted gene, 36640	8325	0.12
chr7_83880073_83880356	0.56	Tlnrd1	talin rod domain containing 1	4091	0.12
chr12_4919724_4920188	0.55	Atad2b	ATPase family, AAA domain containing 2B	2549	0.22
chr19_30427032_30427652	0.55	Gm17885	predicted gene, 17885	63943	0.11
chr11_70648285_70648457	0.55	Rnf167	ring finger protein 167	296	0.65
chr18_37928349_37928500	0.55	Diaph1	diaphanous related formin 1	6957	0.09
chr10_68275304_68275868	0.54	Arid5b	AT rich interactive domain 5B (MRF1-like)	3135	0.29
chr5_139393803_139394522	0.54	Gpr146	G protein-coupled receptor 146	4377	0.13
chr8_109564654_109564805	0.54	Dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38	1132	0.31
chr9_64918332_64919221	0.54	Dennd4a	DENN/MADD domain containing 4A	6293	0.16
chr5_26076023_26076174	0.54	Gm6089	predicted gene 6089	5561	0.12
chr11_98904753_98905026	0.53	Cdc6	cell division cycle 6	2912	0.15
chr13_23307665_23308194	0.53	4930557F10Rik	RIKEN cDNA 4930557F10 gene	5471	0.09
chrX_170676003_170677019	0.53	Asmt	acetylserotonin O-methyltransferase	3867	0.35
chr6_90620588_90620739	0.53	Slc41a3	solute carrier family 41, member 3	1516	0.32
chr5_115068855_115069158	0.53	Sppl3	signal peptide peptidase 3	5361	0.11
chr11_101301119_101301451	0.52	Becn1	beclin 1, autophagy related	452	0.56
chr13_45404312_45405087	0.52	Mylip	myosin regulatory light chain interacting protein	13772	0.2
chr10_61122493_61122987	0.52	Gm44308	predicted gene, 44308	2495	0.22
chr15_38535344_38535808	0.52	Azin1	antizyme inhibitor 1	16310	0.12
chr1_40429474_40429684	0.52	Il1rl1	interleukin 1 receptor-like 1	9	0.98
chr12_51826597_51826775	0.51	Hectd1	HECT domain E3 ubiquitin protein ligase 1	2632	0.28
chr11_65261969_65263039	0.51	Myocd	myocardin	7350	0.22
chr17_24249137_24249431	0.51	Ccnf	cyclin F	288	0.8
chr9_65632066_65632373	0.51	Rbpms2	RNA binding protein with multiple splicing 2	1133	0.45
chrX_85612495_85612646	0.50	Gm44378	predicted gene, 44378	23593	0.18
chr1_86441904_86443224	0.50	Tex44	testis expressed 44	16235	0.11
chr3_116563866_116564174	0.50	Lrrc39	leucine rich repeat containing 39	1042	0.31
chr17_71265690_71266618	0.50	Emilin2	elastin microfibril interfacer 2	1125	0.45
chrX_20659340_20659491	0.50	Uba1	ubiquitin-like modifier activating enzyme 1	12	0.97
chr7_103810339_103810527	0.50	Hbb-bt	hemoglobin, beta adult t chain	3563	0.08
chr14_27809660_27809977	0.49	Erc2	ELKS/RAB6-interacting/CAST family member 2	11260	0.26
chr6_131377564_131377715	0.49	Ybx3	Y box protein 3	602	0.64
chr17_80004778_80004987	0.49	Gm41625	predicted gene, 41625	23220	0.13
chr2_76973822_76974198	0.49	Ttn	titin	6172	0.26
chr14_75178051_75179727	0.49	Lcp1	lymphocyte cytosolic protein 1	2681	0.23
chr11_40690355_40690514	0.49	Mat2b	methionine adenosyltransferase II, beta	2187	0.27
chr13_21936138_21936292	0.49	Zfp184	zinc finger protein 184 (Kruppel-like)	8879	0.06
chr12_98268744_98269348	0.49	Gpr65	G-protein coupled receptor 65	411	0.79
chr11_20635291_20636677	0.49	Sertad2	SERTA domain containing 2	4005	0.26
chr15_82406089_82406449	0.49	Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	302	0.64
chr18_11070118_11070279	0.48	Gata6	GATA binding protein 6	11151	0.22
chr13_22019817_22019986	0.48	Gm11290	predicted gene 11290	2395	0.08
chr9_122118733_122118884	0.48	Gm47122	predicted gene, 47122	337	0.74
chr14_101225620_101225771	0.48	Prr30	proline rich 30	25365	0.22
chr5_74064229_74066220	0.47	Usp46	ubiquitin specific peptidase 46	524	0.65
chr18_80490885_80491036	0.47	Ctdp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	21265	0.15
chr3_95589677_95590017	0.47	Golph3l	golgi phosphoprotein 3-like	857	0.31
chr13_108297218_108298171	0.46	Gm8990	predicted gene 8990	13056	0.16
chr11_99243687_99244404	0.46	Krt222	keratin 222	22	0.97
chr15_23542827_23543053	0.46	Gm6533	predicted gene 6533	53049	0.15
chr6_38554238_38555158	0.45	Luc7l2	LUC7-like 2 (S. cerevisiae)	1025	0.46
chr15_40665481_40666389	0.45	Zfpm2	zinc finger protein, multitype 2	945	0.71
chr3_107321873_107322304	0.45	Rbm15	RNA binding motif protein 15	11013	0.14
chr13_95644732_95645028	0.45	Iqgap2	IQ motif containing GTPase activating protein 2	16218	0.14
chr10_8944239_8945864	0.45	Gm48728	predicted gene, 48728	6898	0.2
chr1_82041385_82041753	0.45	Gm37114	predicted gene, 37114	63611	0.13
chr10_30654343_30655021	0.45	Ncoa7	nuclear receptor coactivator 7	1085	0.45
chr14_50753946_50754101	0.45	Olfr749	olfactory receptor 749	8929	0.09
chr8_83216489_83216744	0.44	Tbc1d9	TBC1 domain family, member 9	42643	0.11
chr14_70705369_70705520	0.44	Xpo7	exportin 7	2591	0.23
chr17_65773364_65773515	0.44	Rab31	RAB31, member RAS oncogene family	687	0.68
chr13_109632540_109633637	0.44	Pde4d	phosphodiesterase 4D, cAMP specific	308	0.95
chr7_90063067_90063244	0.44	Gm44861	predicted gene 44861	20458	0.11
chr8_108867442_108867637	0.44	Gm38318	predicted gene, 38318	23	0.98
chr7_80542241_80542698	0.44	Blm	Bloom syndrome, RecQ like helicase	7350	0.17
chr3_59129379_59129647	0.43	P2ry14	purinergic receptor P2Y, G-protein coupled, 14	1109	0.48
chr11_78076870_78077109	0.43	Eral1	Era (G-protein)-like 1 (E. coli)	1018	0.29

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.2	0.7	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.2	0.7	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.2	0.7	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	2.2	GO:0046085	adenosine metabolic process(GO:0046085)
0.2	0.6	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.2	0.5	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2	1.1	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2	0.5	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.2	0.3	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1	0.6	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.5	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1	1.3	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.6	GO:0061042	vascular wound healing(GO:0061042)
0.1	2.0	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.2	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.1	0.5	GO:0071476	cellular hypotonic response(GO:0071476)
0.1	0.4	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.1	0.3	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.1	0.6	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1	0.6	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1	1.0	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1	0.3	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.1	0.2	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1	0.3	GO:0036394	amylase secretion(GO:0036394)
0.1	0.3	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.1	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.1	0.5	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
0.1	0.5	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1	0.5	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.2	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.1	0.4	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.2	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.1	0.2	GO:0048370	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.1	0.5	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.1	0.2	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.2	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1	0.1	GO:0032346	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.1	0.3	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.1	0.2	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1	0.3	GO:0015705	iodide transport(GO:0015705)
0.1	0.2	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.1	0.2	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1	0.3	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.1	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.2	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.7	GO:0097286	iron ion import(GO:0097286)
0.1	0.1	GO:0036166	phenotypic switching(GO:0036166)
0.1	0.2	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	1.0	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.2	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.4	GO:0015670	carbon dioxide transport(GO:0015670)
0.1	0.2	GO:0000101	sulfur amino acid transport(GO:0000101)
0.1	0.2	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1	0.4	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.1	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1	0.2	GO:0043366	beta selection(GO:0043366)
0.1	0.4	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	0.3	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.9	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.1	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.2	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.0	GO:0003130	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0	0.1	GO:0060931	sinoatrial node cell development(GO:0060931)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0	0.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.0	GO:0061325	cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.4	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.2	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.0	0.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.2	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.1	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	0.1	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.0	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.0	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0	0.2	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.3	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.2	GO:0007100	mitotic centrosome separation(GO:0007100) regulation of mitotic centrosome separation(GO:0046602)
0.0	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.2	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392)
0.0	0.2	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.2	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.3	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:1902996	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.2	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.2	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.0	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.2	GO:0060352	cell adhesion molecule production(GO:0060352)
0.0	0.2	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.2	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.1	GO:1905206	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.3	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.5	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0061074	regulation of neural retina development(GO:0061074)
0.0	0.0	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.0	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.2	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	1.2	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.1	GO:2000726	negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0032905	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.0	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.0	0.0	GO:2000196	positive regulation of female gonad development(GO:2000196)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0030578	PML body organization(GO:0030578)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.2	GO:0035879	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.2	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.0	0.4	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.5	GO:0051180	vitamin transport(GO:0051180)
0.0	0.0	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.1	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.0	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.3	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.3	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.0	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.0	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
0.0	0.1	GO:1901536	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0	0.0	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.0	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.0	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.0	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.2	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0	0.0	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.5	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.1	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.0	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0	0.0	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.3	GO:0090382	phagosome maturation(GO:0090382)
0.0	0.0	GO:1901256	macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0	0.0	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.2	GO:0021702	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.0	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.0	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.1	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.0	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	0.9	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	1.0	GO:0030038	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	0.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.2	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.2	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.0	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.0	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0007614	short-term memory(GO:0007614)
0.0	0.0	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.0	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.0	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.2	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.2	GO:0042026	protein refolding(GO:0042026)
0.0	0.0	GO:1903209	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177) positive regulation of oxidative stress-induced cell death(GO:1903209)
0.0	0.0	GO:1905048	regulation of metallopeptidase activity(GO:1905048)
0.0	0.1	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0	0.1	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.0	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.0	GO:0036490	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.0	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.0	GO:1902267	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.0	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0018119	peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0021764	amygdala development(GO:0021764)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.3	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0014820	tonic smooth muscle contraction(GO:0014820)
0.0	0.1	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.0	0.3	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.0	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.1	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.0	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.1	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.3	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.0	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.4	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.0	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.2	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.0	0.1	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0061591	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0	0.2	GO:0006298	mismatch repair(GO:0006298)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.8	GO:0005859	muscle myosin complex(GO:0005859)
0.2	0.7	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.2	0.5	GO:0097443	sorting endosome(GO:0097443)
0.2	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.5	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.1	1.0	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.5	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.3	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.1	0.4	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.2	GO:0032437	cuticular plate(GO:0032437)
0.1	0.2	GO:0097149	centralspindlin complex(GO:0097149)
0.1	0.3	GO:0031094	platelet dense tubular network(GO:0031094)
0.1	0.9	GO:0005916	fascia adherens(GO:0005916)
0.1	0.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.2	GO:0030478	actin cap(GO:0030478)
0.1	0.2	GO:0000811	GINS complex(GO:0000811)
0.1	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.6	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.0	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.3	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.4	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	2.0	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.2	GO:0032982	myosin filament(GO:0032982)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.4	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	1.0	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.0	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	3.0	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.0	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.2	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.0	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.0	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.8	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.7	GO:0000922	spindle pole(GO:0000922)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.5	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	1.0	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.5	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.3	GO:0031433	telethonin binding(GO:0031433)
0.3	2.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.2	0.6	GO:0055100	adiponectin binding(GO:0055100)
0.2	0.7	GO:0051434	BH3 domain binding(GO:0051434)
0.2	2.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	0.8	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	1.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.6	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	1.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.5	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.5	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.6	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.3	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.1	0.6	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.4	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.8	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.3	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.2	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.1	0.3	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	0.6	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.3	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.3	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	0.2	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.3	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.2	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.2	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.1	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.0	0.3	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.6	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.3	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.5	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.3	GO:0032183	SUMO binding(GO:0032183)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.4	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.6	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.3	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.5	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0090079	translation activator activity(GO:0008494) translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.6	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	1.3	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.0	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.2	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.1	GO:0052724	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.0	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.0	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0086056	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.1	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.0	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.7	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.4	GO:0034792	sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0	0.6	GO:0017022	myosin binding(GO:0017022)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.4	GO:0042605	peptide antigen binding(GO:0042605)
0.0	1.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0015250	water channel activity(GO:0015250)
0.0	0.1	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.9	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.4	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.7	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	PID FGF PATHWAY	FGF signaling pathway
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.1	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.8	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.5	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.4	PID ATM PATHWAY	ATM pathway
0.0	0.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.6	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	1.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	0.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.1	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.5	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	2.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.0	0.4	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.8	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.3	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.1	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.2	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors

Results for Pou3f3

Z-value: 0.64

Motif logo

Transcription factors associated with Pou3f3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Pou3f3 motif across conditions

Conditions sorted by the z-value of the Pou3f3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: