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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Ppard

Z-value: 0.55

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Transcription factors associated with Ppard

Gene Symbol	Gene ID	Gene Info
Ppard Ensembl NCBI MGI UniProt	ENSMUSG00000002250.9	peroxisome proliferator activator receptor delta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_28237484_28238264	Ppard	5067	0.123219	0.30	2.0e-02	Click!
chr17_28299783_28299934	Ppard	6612	0.105217	-0.29	2.4e-02	Click!
chr17_28237285_28237456	Ppard	4563	0.126914	0.28	3.1e-02	Click!
chr17_28236269_28236726	Ppard	3690	0.137032	0.26	4.6e-02	Click!
chr17_28236952_28237103	Ppard	4220	0.130181	0.24	6.4e-02	Click!

Activity of the Ppard motif across conditions

Conditions sorted by the z-value of the Ppard motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_75655315_75655603	1.91	Akap13	A kinase (PRKA) anchor protein 13	11274	0.18
chr4_152447653_152448768	1.52	Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	531	0.76
chr15_78245409_78246081	1.39	Ncf4	neutrophil cytosolic factor 4	901	0.49
chr11_103102696_103105788	1.27	Acbd4	acyl-Coenzyme A binding domain containing 4	463	0.7
chr5_119685576_119687800	1.17	Tbx3os2	T-box 3, opposite strand 2	4530	0.17
chr4_118429529_118430133	1.16	Elovl1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	130	0.92
chr6_56900814_56901268	1.16	Nt5c3	5'-nucleotidase, cytosolic III	842	0.51
chr1_91057148_91057757	1.16	Lrrfip1	leucine rich repeat (in FLII) interacting protein 1	3866	0.24
chr2_167691999_167692442	1.08	A530013C23Rik	RIKEN cDNA A530013C23 gene	1039	0.35
chr6_55324306_55324538	0.94	Aqp1	aquaporin 1	12010	0.14
chr6_125312691_125314238	0.83	Ltbr	lymphotoxin B receptor	199	0.88
chr10_75939108_75939976	0.82	Gm867	predicted gene 867	1069	0.25
chr6_72391190_72391463	0.82	Vamp8	vesicle-associated membrane protein 8	623	0.55
chr18_38248552_38248782	0.82	1700086O06Rik	RIKEN cDNA 1700086O06 gene	1211	0.27
chr10_12812573_12812894	0.81	Utrn	utrophin	816	0.64
chr6_72392212_72392477	0.74	Vamp8	vesicle-associated membrane protein 8	1641	0.22
chr9_107982030_107984233	0.72	Gm20661	predicted gene 20661	38	0.54
chr2_155988856_155989174	0.72	Cep250	centrosomal protein 250	3100	0.14
chr2_35610114_35610843	0.72	Dab2ip	disabled 2 interacting protein	11503	0.2
chr16_90739931_90740383	0.72	Mrap	melanocortin 2 receptor accessory protein	1833	0.28
chr6_29271003_29271699	0.71	Hilpda	hypoxia inducible lipid droplet associated	1137	0.37
chr11_98446534_98448432	0.68	Grb7	growth factor receptor bound protein 7	415	0.68
chr8_111573318_111574249	0.67	Znrf1	zinc and ring finger 1	11943	0.18
chr9_40323395_40324376	0.66	1700110K17Rik	RIKEN cDNA 1700110K17 gene	459	0.71
chr2_85060620_85061523	0.66	Tnks1bp1	tankyrase 1 binding protein 1	107	0.95
chr17_33778675_33780469	0.65	Angptl4	angiopoietin-like 4	429	0.65
chr3_121200717_121201242	0.65	Gm5710	predicted gene 5710	19882	0.13
chr5_107874374_107875235	0.64	Evi5	ecotropic viral integration site 5	240	0.86
chr14_63270328_63271232	0.63	Gata4	GATA binding protein 4	344	0.87
chr11_95778707_95778988	0.62	Polr2k-ps	polymerase (RNA) II (DNA directed) polypeptide K, pseudogene	17356	0.11
chr17_80833726_80834127	0.62	C230072F16Rik	RIKEN cDNA C230072F16 gene	62867	0.11
chr15_82379480_82380754	0.61	Cyp2d22	cytochrome P450, family 2, subfamily d, polypeptide 22	126	0.88
chr7_127014020_127014913	0.60	Mvp	major vault protein	84	0.88
chr6_83247043_83247210	0.60	Slc4a5	solute carrier family 4, sodium bicarbonate cotransporter, member 5	9751	0.12
chr2_181241290_181242534	0.59	Helz2	helicase with zinc finger 2, transcriptional coactivator	51	0.95
chr16_44015370_44016774	0.58	Gramd1c	GRAM domain containing 1C	364	0.83
chr10_69348031_69348525	0.58	Cdk1	cyclin-dependent kinase 1	2552	0.25
chr11_119392018_119392570	0.57	Rnf213	ring finger protein 213	806	0.49
chr11_102356812_102357313	0.56	Slc4a1	solute carrier family 4 (anion exchanger), member 1	3506	0.13
chr19_55941741_55942415	0.56	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	43769	0.16
chr11_65266805_65267363	0.55	Myocd	myocardin	2770	0.29
chr15_76118017_76119354	0.55	Eppk1	epiplakin 1	1510	0.2
chr4_59196867_59197419	0.55	Ugcg	UDP-glucose ceramide glucosyltransferase	7585	0.18
chr11_79071094_79071622	0.54	Ksr1	kinase suppressor of ras 1	3128	0.28
chr7_97454829_97454980	0.54	Kctd14	potassium channel tetramerisation domain containing 14	1682	0.29
chr14_48538424_48539155	0.53	4930572G02Rik	RIKEN cDNA 4930572G02 gene	430	0.76
chr6_142470696_142471396	0.53	Gys2	glycogen synthase 2	2063	0.3
chr11_83849571_83850989	0.53	Hnf1b	HNF1 homeobox B	217	0.83
chr1_171388990_171389691	0.53	Arhgap30	Rho GTPase activating protein 30	341	0.72
chr8_79680146_79681210	0.52	Tpd52-ps	tumor protein D52, pseudogene	128	0.95
chr15_67127618_67128557	0.52	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	936	0.68
chr5_91849602_91849753	0.52	Gm5558	predicted gene 5558	42604	0.1
chr5_124049658_124050948	0.52	Gm43661	predicted gene 43661	2049	0.18
chr11_32296600_32297646	0.52	Hba-a2	hemoglobin alpha, adult chain 2	495	0.66
chr2_127364227_127365175	0.52	Adra2b	adrenergic receptor, alpha 2b	1415	0.34
chr9_103287942_103288250	0.52	1300017J02Rik	RIKEN cDNA 1300017J02 gene	128	0.96
chr8_94964158_94964452	0.52	Gm10286	predicted gene 10286	5449	0.13
chr11_55073341_55073492	0.51	Ccdc69	coiled-coil domain containing 69	4691	0.15
chr15_103453834_103454841	0.51	Nckap1l	NCK associated protein 1 like	510	0.7
chr11_96343236_96346574	0.51	Hoxb3	homeobox B3	1136	0.24
chr10_70127197_70127431	0.50	Ccdc6	coiled-coil domain containing 6	30193	0.2
chr11_32283784_32284776	0.50	Hba-a1	hemoglobin alpha, adult chain 1	469	0.66
chr16_30407828_30408280	0.50	Atp13a3	ATPase type 13A3	2079	0.35
chr2_72180043_72180526	0.49	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	591	0.76
chr9_123124082_123124233	0.49	Exosc7	exosome component 7	2228	0.19
chr4_135405096_135405380	0.49	Gm12990	predicted gene 12990	1582	0.22
chr5_113136296_113136937	0.48	2900026A02Rik	RIKEN cDNA 2900026A02 gene	1370	0.27
chr13_37799590_37800028	0.48	Gm46411	predicted gene, 46411	19	0.97
chr11_120530321_120531885	0.48	Gcgr	glucagon receptor	329	0.46
chr3_154192384_154192535	0.48	Slc44a5	solute carrier family 44, member 5	30023	0.16
chr10_80347716_80349512	0.48	Adamtsl5	ADAMTS-like 5	202	0.82
chr3_87767082_87768667	0.47	Pear1	platelet endothelial aggregation receptor 1	1061	0.43
chr12_105757848_105758442	0.47	Ak7	adenylate kinase 7	12870	0.17
chr5_108674592_108675616	0.47	Slc26a1	solute carrier family 26 (sulfate transporter), member 1	319	0.8
chr8_122697299_122697450	0.47	Gm10612	predicted gene 10612	486	0.63
chr5_89456826_89457321	0.47	Gc	vitamin D binding protein	825	0.68
chr6_72388069_72388633	0.46	Vamp8	vesicle-associated membrane protein 8	1560	0.22
chr11_94997783_94998270	0.46	Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	1962	0.2
chr14_65380585_65381143	0.46	Zfp395	zinc finger protein 395	5471	0.19
chr2_38531311_38531917	0.46	Gm35808	predicted gene, 35808	4093	0.15
chr4_43522717_43524714	0.46	Tpm2	tropomyosin 2, beta	50	0.93
chr11_20634522_20634924	0.46	Sertad2	SERTA domain containing 2	2744	0.3
chr11_109860046_109860775	0.46	1700023C21Rik	RIKEN cDNA 1700023C21 gene	14532	0.18
chr9_22135450_22135674	0.46	Acp5	acid phosphatase 5, tartrate resistant	129	0.9
chr10_7473717_7473913	0.45	Ulbp1	UL16 binding protein 1	177	0.95
chr10_4611597_4612860	0.45	Esr1	estrogen receptor 1 (alpha)	207	0.95
chr16_32612719_32613020	0.45	Tfrc	transferrin receptor	2363	0.22
chr15_77754021_77754265	0.45	Apol8	apolipoprotein L 8	1096	0.34
chr9_108047652_108047803	0.45	Gmppb	GDP-mannose pyrophosphorylase B	1515	0.14
chr9_31253741_31253909	0.45	Gm7244	predicted gene 7244	20996	0.14
chr18_61035503_61036684	0.45	Cdx1	caudal type homeobox 1	106	0.95
chr8_25848584_25848735	0.44	Kcnu1	potassium channel, subfamily U, member 1	964	0.33
chr6_90324065_90325476	0.43	Chst13	carbohydrate sulfotransferase 13	415	0.73
chr4_150220525_150221094	0.43	Gm13094	predicted gene 13094	7226	0.14
chr11_69915606_69917001	0.43	Gps2	G protein pathway suppressor 2	262	0.72
chr7_44482378_44484029	0.43	5430431A17Rik	RIKEN cDNA 5430431A17 gene	1314	0.19
chr8_13202008_13202379	0.42	2810030D12Rik	RIKEN cDNA 2810030D12 gene	1373	0.23
chr8_79372752_79373201	0.42	Smad1	SMAD family member 1	16298	0.17
chr3_19958576_19959194	0.42	Cp	ceruloplasmin	1601	0.35
chr11_120628124_120628346	0.41	Mafg	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)	1913	0.1
chr7_140835042_140835946	0.41	Urah	urate (5-hydroxyiso-) hydrolase	130	0.88
chr6_131383705_131383961	0.41	Gm22362	predicted gene, 22362	3427	0.17
chr3_86797094_86797252	0.41	Dclk2	doublecortin-like kinase 2	839	0.63
chr2_27246009_27247328	0.41	Sardh	sarcosine dehydrogenase	180	0.94
chr4_106462824_106463256	0.41	Pcsk9	proprotein convertase subtilisin/kexin type 9	1289	0.37
chr2_173031954_173032465	0.41	Gm14453	predicted gene 14453	2371	0.21
chr8_122321302_122321696	0.40	Zfpm1	zinc finger protein, multitype 1	12199	0.12
chr11_4117645_4117796	0.40	Sec14l2	SEC14-like lipid binding 2	976	0.33
chr19_5662426_5664007	0.39	Sipa1	signal-induced proliferation associated gene 1	404	0.63
chr9_57639659_57641273	0.39	Csk	c-src tyrosine kinase	4643	0.13
chr5_96919772_96919923	0.38	Gm8013	predicted gene 8013	1425	0.23
chr1_74036048_74037430	0.38	Tns1	tensin 1	394	0.88
chr7_132494201_132494423	0.38	Gm4587	predicted gene 4587	10654	0.18
chr3_58681851_58682065	0.38	Siah2	siah E3 ubiquitin protein ligase 2	4079	0.15
chr16_8746356_8746577	0.37	Usp7	ubiquitin specific peptidase 7	8046	0.16
chr8_84908331_84909758	0.37	Dnase2a	deoxyribonuclease II alpha	313	0.72
chr5_36621046_36621447	0.37	D5Ertd579e	DNA segment, Chr 5, ERATO Doi 579, expressed	9	0.96
chr13_37345719_37346245	0.37	Ly86	lymphocyte antigen 86	593	0.71
chr4_137048694_137049053	0.37	Zbtb40	zinc finger and BTB domain containing 40	72	0.97
chr5_143528879_143529030	0.37	Rac1	Rac family small GTPase 1	918	0.45
chr6_40585006_40585430	0.37	Clec5a	C-type lectin domain family 5, member a	572	0.65
chr4_83315034_83315192	0.37	Ttc39b	tetratricopeptide repeat domain 39B	9076	0.19
chr10_116558082_116558233	0.37	Gm49344	predicted gene, 49344	8625	0.14
chr11_95778990_95779141	0.37	Polr2k-ps	polymerase (RNA) II (DNA directed) polypeptide K, pseudogene	17574	0.11
chrX_73909796_73911465	0.36	Arhgap4	Rho GTPase activating protein 4	599	0.57
chr15_36644507_36644990	0.36	Gm6704	predicted gene 6704	14879	0.12
chr2_158145151_158146425	0.35	Tgm2	transglutaminase 2, C polypeptide	578	0.71
chr11_73326431_73327128	0.35	Aspa	aspartoacylase	28	0.95
chr2_131497015_131497229	0.35	Smox	spermine oxidase	4858	0.2
chr1_135133209_135134183	0.35	Ptpn7	protein tyrosine phosphatase, non-receptor type 7	387	0.67
chr14_55105801_55106847	0.35	Ap1g2	adaptor protein complex AP-1, gamma 2 subunit	57	0.94
chr2_30266436_30267404	0.35	Phyhd1	phytanoyl-CoA dioxygenase domain containing 1	57	0.94
chr11_73136220_73136518	0.35	Haspin	histone H3 associated protein kinase	1925	0.22
chr2_180724979_180726144	0.35	Slc17a9	solute carrier family 17, member 9	161	0.92
chr4_8707697_8708271	0.34	Chd7	chromodomain helicase DNA binding protein 7	2356	0.38
chr6_136938496_136939168	0.34	Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	759	0.55
chr11_98586074_98586564	0.34	Ormdl3	ORM1-like 3 (S. cerevisiae)	1049	0.35
chr10_59403301_59404650	0.34	Pla2g12b	phospholipase A2, group XIIB	315	0.88
chr7_83880797_83881971	0.34	Tlnrd1	talin rod domain containing 1	2921	0.13
chrX_53268548_53269792	0.34	Fam122b	family with sequence similarity 122, member B	150	0.94
chr10_59440391_59440627	0.34	Oit3	oncoprotein induced transcript 3	1269	0.43
chr2_173047915_173048486	0.34	Gm14453	predicted gene 14453	13620	0.13
chr2_84936571_84938205	0.34	Slc43a3	solute carrier family 43, member 3	498	0.71
chr17_81735907_81736099	0.34	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	2374	0.4
chr4_11759825_11760000	0.34	Cdh17	cadherin 17	1719	0.41
chr1_169453592_169453819	0.34	Gm5265	predicted pseudogene 5265	164	0.97
chr3_88145024_88146544	0.34	Mef2d	myocyte enhancer factor 2D	3210	0.14
chr15_89209951_89210279	0.34	Ppp6r2	protein phosphatase 6, regulatory subunit 2	1438	0.26
chr4_57914999_57916744	0.33	D630039A03Rik	RIKEN cDNA D630039A03 gene	426	0.84
chr7_109601527_109601678	0.33	Denn2b	DENN domain containing 2B	1063	0.5
chr11_49050525_49051195	0.33	Olfr56	olfactory receptor 56	127	0.66
chr11_4987942_4988093	0.33	Ap1b1	adaptor protein complex AP-1, beta 1 subunit	1083	0.42
chr12_76535555_76536098	0.32	Plekhg3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	2206	0.21
chr6_87809573_87810010	0.32	Rab43	RAB43, member RAS oncogene family	34	0.93
chr4_117928946_117930077	0.32	Artn	artemin	14	0.96
chr7_99237308_99238665	0.32	Mogat2	monoacylglycerol O-acyltransferase 2	608	0.62
chr7_102565536_102565805	0.32	Trim21	tripartite motif-containing 21	184	0.84
chr14_40992686_40992932	0.32	Prxl2a	peroxiredoxin like 2A	10295	0.17
chr4_43037093_43037817	0.32	Fam214b	family with sequence similarity 214, member B	154	0.91
chr3_59129062_59129246	0.32	P2ry14	purinergic receptor P2Y, G-protein coupled, 14	1468	0.38
chr5_35727822_35729089	0.32	Sh3tc1	SH3 domain and tetratricopeptide repeats 1	557	0.73
chr12_109452854_109454456	0.32	Dlk1	delta like non-canonical Notch ligand 1	0	0.96
chr5_139793597_139793944	0.32	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	2236	0.2
chr4_107921827_107922539	0.32	Cpt2	carnitine palmitoyltransferase 2	1264	0.35
chr10_78086930_78087081	0.31	Icosl	icos ligand	13666	0.12
chr15_78412939_78413161	0.31	Mpst	mercaptopyruvate sulfurtransferase	3068	0.12
chr9_62420746_62421699	0.31	Coro2b	coronin, actin binding protein, 2B	6779	0.24
chr4_117840171_117840322	0.31	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	4808	0.13
chr8_105850624_105850775	0.31	Cenpt	centromere protein T	1270	0.23
chr13_73767696_73767973	0.31	Slc12a7	solute carrier family 12, member 7	4095	0.21
chr7_110097583_110097734	0.31	Zfp143	zinc finger protein 143	6029	0.13
chr9_42460796_42461392	0.31	Tbcel	tubulin folding cofactor E-like	367	0.85
chr10_18446906_18447110	0.30	Nhsl1	NHS-like 1	22880	0.22
chr15_83165887_83166710	0.30	Cyb5r3	cytochrome b5 reductase 3	3879	0.12
chr19_53796222_53796373	0.30	Rbm20	RNA binding motif protein 20	2989	0.23
chr11_75165245_75169157	0.30	Hic1	hypermethylated in cancer 1	945	0.35
chr1_129956479_129957256	0.30	Gm37278	predicted gene, 37278	13705	0.22
chr6_145121642_145121793	0.30	Lrmp	lymphoid-restricted membrane protein	22	0.97
chr2_170153321_170154276	0.30	Zfp217	zinc finger protein 217	5695	0.31
chr7_78914537_78914688	0.29	Isg20	interferon-stimulated protein	283	0.86
chr13_9107287_9107639	0.29	Larp4b	La ribonucleoprotein domain family, member 4B	13481	0.15
chr5_52990921_52991150	0.29	5033403H07Rik	RIKEN cDNA 5033403H07 gene	1257	0.4
chr5_149265060_149265699	0.29	Alox5ap	arachidonate 5-lipoxygenase activating protein	32	0.95
chrX_85577312_85577893	0.29	Tab3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	3452	0.27
chr11_87748405_87749482	0.29	Mir142hg	Mir142 host gene (non-protein coding)	6634	0.09
chr10_78297357_78298225	0.29	Agpat3	1-acylglycerol-3-phosphate O-acyltransferase 3	407	0.49
chr11_97442581_97443059	0.29	Arhgap23	Rho GTPase activating protein 23	6535	0.17
chr4_133007332_133008511	0.29	Ahdc1	AT hook, DNA binding motif, containing 1	3339	0.22
chr14_48589666_48590768	0.28	Gm49120	predicted gene, 49120	382	0.79
chr19_53186353_53186984	0.28	Add3	adducin 3 (gamma)	5072	0.18
chr5_122292013_122292461	0.28	Pptc7	PTC7 protein phosphatase homolog	3535	0.14
chr19_5724002_5724609	0.28	Ehbp1l1	EH domain binding protein 1-like 1	1965	0.11
chr5_24855106_24855299	0.28	Rheb	Ras homolog enriched in brain	12578	0.14
chr16_91929524_91929738	0.28	D430001F17Rik	RIKEN cDNA D430001F17 gene	1606	0.21
chr8_117201307_117201734	0.28	Gan	giant axonal neuropathy	43383	0.14
chr17_86293099_86293835	0.28	2010106C02Rik	RIKEN cDNA 2010106C02 gene	6289	0.29
chr1_87573319_87573846	0.28	Ngef	neuronal guanine nucleotide exchange factor	288	0.62
chr1_193001250_193001648	0.28	Syt14	synaptotagmin XIV	34195	0.13
chr7_128205575_128206445	0.28	Cox6a2	cytochrome c oxidase subunit 6A2	377	0.67
chr18_48693060_48693350	0.27	Gm50229	predicted gene, 50229	29481	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ppard

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0036394	amylase secretion(GO:0036394)
0.2	1.3	GO:0070995	NADPH oxidation(GO:0070995)
0.2	0.6	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.2	0.5	GO:0007525	somatic muscle development(GO:0007525)
0.2	1.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.4	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1	0.5	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1	0.4	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.3	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.4	GO:0072095	regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.1	0.3	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.1	0.4	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.3	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.4	GO:0006083	acetate metabolic process(GO:0006083)
0.1	0.3	GO:0033058	directional locomotion(GO:0033058)
0.1	0.3	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.3	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.1	0.4	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.2	GO:0071462	cellular response to water stimulus(GO:0071462)
0.1	0.2	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.1	0.2	GO:0010159	specification of organ position(GO:0010159)
0.1	0.4	GO:0019532	oxalate transport(GO:0019532)
0.1	0.3	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.1	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	0.2	GO:0015793	glycerol transport(GO:0015793)
0.1	0.3	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.1	0.2	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1	0.7	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.2	GO:1904193	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.2	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.6	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.1	0.2	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1	0.2	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.3	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1	0.2	GO:0070889	platelet alpha granule organization(GO:0070889)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.4	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1	0.2	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.4	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.2	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.2	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.1	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.1	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.5	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0031296	B cell costimulation(GO:0031296)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.2	GO:0033762	response to glucagon(GO:0033762)
0.0	0.1	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.2	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	0.4	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.1	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.4	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.4	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.0	0.2	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.1	GO:0002554	serotonin secretion by platelet(GO:0002554)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0071655	macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0	0.0	GO:0018214	protein carboxylation(GO:0018214)
0.0	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.0	GO:1901671	positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.1	GO:0002432	granuloma formation(GO:0002432)
0.0	0.7	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.2	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.2	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.1	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0	0.2	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0060214	endocardium formation(GO:0060214)
0.0	0.1	GO:0000432	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0	0.1	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.0	0.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.1	GO:0034473	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.0	GO:0071608	macrophage inflammatory protein-1 alpha production(GO:0071608)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:1904659	glucose transmembrane transport(GO:1904659)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0015781	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.2	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.2	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.2	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.1	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.6	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.4	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.2	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:0044557	relaxation of smooth muscle(GO:0044557)
0.0	0.1	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.0	0.0	GO:0001781	neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.2	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.0	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.2	GO:0090205	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.1	GO:0006548	histidine metabolic process(GO:0006547) histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0060931	sinoatrial node cell development(GO:0060931)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.0	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.1	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0001765	membrane raft assembly(GO:0001765)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.0	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0	0.0	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.5	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.2	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.2	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.2	GO:0046688	response to copper ion(GO:0046688)
0.0	0.0	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.2	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.2	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.1	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.2	GO:0071281	cellular response to iron ion(GO:0071281)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.4	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.2	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.4	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.1	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.1	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.0	0.2	GO:0019430	removal of superoxide radicals(GO:0019430)
0.0	0.1	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0009092	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.0	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0009750	response to fructose(GO:0009750) cellular response to fructose stimulus(GO:0071332)
0.0	0.0	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.1	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.0	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.0	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
0.0	0.0	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.2	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0015697	quaternary ammonium group transport(GO:0015697)
0.0	0.0	GO:0043366	beta selection(GO:0043366)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.0	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.0	0.7	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.1	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.0	0.0	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.1	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0	0.3	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.0	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.0	GO:0045404	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0	0.0	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.0	0.0	GO:1900086	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.0	GO:1905063	regulation of vascular smooth muscle cell differentiation(GO:1905063)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.0	GO:0035928	RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
0.0	0.0	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.0	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.0	GO:0050904	diapedesis(GO:0050904)
0.0	0.0	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.1	GO:0019441	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.0	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.0	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.0	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.0	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.1	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.0	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.0	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.0	0.3	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.1	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0032367	intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.0	GO:0048382	mesendoderm development(GO:0048382) corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.3	GO:0006695	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.3	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.7	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.2	GO:0097451	glial limiting end-foot(GO:0097451)
0.1	0.2	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.1	0.6	GO:0070938	contractile ring(GO:0070938)
0.1	0.2	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.7	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.4	GO:0031209	SCAR complex(GO:0031209)
0.0	0.3	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.1	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.1	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.5	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0001674	female germ cell nucleus(GO:0001674)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.9	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.7	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	1.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.0	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.0	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.0	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.0	GO:0005608	laminin-3 complex(GO:0005608)
0.0	0.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0031720	haptoglobin binding(GO:0031720)
0.2	1.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.6	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.4	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.4	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.6	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.7	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.2	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.2	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1	0.2	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.4	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1	0.3	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.6	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.3	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	1.2	GO:0044105	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.5	GO:0017166	vinculin binding(GO:0017166)
0.0	0.3	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.3	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.4	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.2	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.1	GO:0043199	sulfate binding(GO:0043199)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.2	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.8	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.5	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.4	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.5	GO:0005542	folic acid binding(GO:0005542)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.2	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.0	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.2	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.0	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.4	GO:0043883	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0016502	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.3	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.0	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0038100	nodal binding(GO:0038100)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.2	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.0	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.2	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.0	GO:0052723	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0005536	glucose binding(GO:0005536)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.4	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.5	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0016675	oxidoreductase activity, acting on a heme group of donors(GO:0016675)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.1	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0	0.2	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.1	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.0	GO:1990932	5.8S rRNA binding(GO:1990932)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.7	PID AURORA B PATHWAY	Aurora B signaling
0.1	PID RHOA PATHWAY	RhoA signaling pathway
0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.5	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.3	PID BARD1 PATHWAY	BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	0.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	1.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.4	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway

Results for Ppard

Z-value: 0.55

Motif logo

Transcription factors associated with Ppard

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Ppard motif across conditions

Conditions sorted by the z-value of the Ppard motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ppard

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: