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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Rarb

Z-value: 0.52

Motif logo

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Transcription factors associated with Rarb

Gene Symbol Gene ID Gene Info
Rarb
ENSMUSG00000017491.8 retinoic acid receptor, beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_16574044_16575901Rarb730.919664-0.436.8e-04Click!
chr14_16554767_16555445Rarb199390.2061850.331.0e-02Click!
chr14_16554164_16554315Rarb208060.2044510.321.1e-02Click!
chr14_16847192_16847623Rarb282510.227952-0.311.6e-02Click!
chr14_16733832_16734108Rarb850350.0976700.211.0e-01Click!

Activity of the Rarb motif across conditions

Conditions sorted by the z-value of the Rarb motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_102360845_102363484 3.04 Slc4a1
 solute carrier family 4 (anion exchanger), member 1
 1540
 0.24
chr8_23035959_23037041 1.91 Ank1
 ankyrin 1, erythroid
 1269
 0.45
chrX_150547515_150548479 1.76 Alas2
 aminolevulinic acid synthase 2, erythroid
 538
 0.44
chr9_121451719_121452290 1.30 Trak1
 trafficking protein, kinesin binding 1
 2292
 0.28
chr11_58275551_58275913 1.27 4930438A08Rik
 RIKEN cDNA 4930438A08 gene
 672
 0.56
chr6_83068298_83071797 1.23 Tlx2
 T cell leukemia, homeobox 2
 178
 0.81
chr1_177494861_177495402 1.10 Gm37306
 predicted gene, 37306
 27753
 0.14
chr2_173034791_173035156 1.06 Gm14453
 predicted gene 14453
 393
 0.8
chr11_83848300_83848853 0.98 Gm12576
 predicted gene 12576
 917
 0.43
chr8_67948178_67948899 0.97 Psd3
 pleckstrin and Sec7 domain containing 3
 3341
 0.28
chr11_19986765_19987519 0.91 Spred2
 sprouty-related EVH1 domain containing 2
 32572
 0.2
chr1_157526787_157526938 0.89 Sec16b
 SEC16 homolog B (S. cerevisiae)
 715
 0.64
chr10_77109606_77109767 0.87 Col18a1
 collagen, type XVIII, alpha 1
 4019
 0.21
chr3_131269218_131269951 0.87 Hadh
 hydroxyacyl-Coenzyme A dehydrogenase
 2440
 0.24
chr11_95354322_95355144 0.85 Fam117a
 family with sequence similarity 117, member A
 14771
 0.11
chr15_35295781_35297332 0.85 Osr2
 odd-skipped related 2
 445
 0.83
chr4_58546126_58546553 0.85 Lpar1
 lysophosphatidic acid receptor 1
 2062
 0.34
chr8_3354301_3354483 0.84 Arhgef18
 rho/rac guanine nucleotide exchange factor (GEF) 18
 932
 0.59
chr1_172548699_172548872 0.72 4933439K11Rik
 RIKEN cDNA 4933439K11 gene
 1884
 0.2
chr5_52990921_52991150 0.72 5033403H07Rik
 RIKEN cDNA 5033403H07 gene
 1257
 0.4
chr14_21078036_21078470 0.72 Adk
 adenosine kinase
 2101
 0.35
chrX_106839224_106840351 0.71 Rtl3
 retrotransposon Gag like 3
 857
 0.6
chr15_77973908_77974338 0.66 Eif3d
 eukaryotic translation initiation factor 3, subunit D
 3310
 0.19
chr10_68157085_68157396 0.63 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 20614
 0.24
chr16_14310141_14310292 0.60 Gm15868
 predicted gene 15868
 1625
 0.3
chr17_65606813_65607080 0.60 Vapa
 vesicle-associated membrane protein, associated protein A
 6609
 0.17
chr10_86024993_86025483 0.60 A230060F14Rik
 RIKEN cDNA A230060F14 gene
 2909
 0.15
chr10_121263429_121264335 0.59 Gm35404
 predicted gene, 35404
 20880
 0.14
chr6_118771100_118771251 0.57 Cacna1c
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 9149
 0.27
chr3_14641184_14642360 0.57 Car13
 carbonic anhydrase 13
 45
 0.97
chr8_70490321_70491265 0.57 Crlf1
 cytokine receptor-like factor 1
 2365
 0.12
chr4_109439636_109440032 0.56 Ttc39a
 tetratricopeptide repeat domain 39A
 18892
 0.15
chr10_8944239_8945864 0.55 Gm48728
 predicted gene, 48728
 6898
 0.2
chr7_25379357_25380698 0.55 4732471J01Rik
 RIKEN cDNA 4732471J01 gene
 3204
 0.12
chr9_22135450_22135674 0.54 Acp5
 acid phosphatase 5, tartrate resistant
 129
 0.9
chr6_34517984_34518174 0.54 Gm13860
 predicted gene 13860
 15474
 0.17
chrX_38575133_38575425 0.54 Cul4b
 cullin 4B
 904
 0.58
chr3_95652966_95653117 0.53 Mcl1
 myeloid cell leukemia sequence 1
 5747
 0.11
chr5_137569837_137570642 0.53 Tfr2
 transferrin receptor 2
 370
 0.67
chr2_172261076_172261248 0.53 Mc3r
 melanocortin 3 receptor
 12670
 0.17
chr5_115945354_115946075 0.52 Cit
 citron
 417
 0.82
chr11_60477952_60478643 0.50 Myo15
 myosin XV
 1618
 0.23
chr16_31066399_31067041 0.50 Xxylt1
 xyloside xylosyltransferase 1
 1133
 0.51
chr7_100463756_100463979 0.50 C2cd3
 C2 calcium-dependent domain containing 3
 344
 0.77
chr4_141558647_141558798 0.49 B330016D10Rik
 RIKEN cDNA B330016D10 gene
 12533
 0.12
chr1_149960555_149961570 0.49 Pla2g4a
 phospholipase A2, group IVA (cytosolic, calcium-dependent)
 193
 0.96
chr16_18286012_18286942 0.48 Gm24572
 predicted gene, 24572
 1840
 0.14
chr15_81870008_81870701 0.48 Phf5a
 PHD finger protein 5A
 1311
 0.23
chr11_53422380_53423106 0.48 Leap2
 liver-expressed antimicrobial peptide 2
 427
 0.66
chr9_106357304_106357455 0.47 Dusp7
 dual specificity phosphatase 7
 11253
 0.12
chr2_116020004_116021542 0.47 Meis2
 Meis homeobox 2
 21273
 0.19
chr10_88349909_88350060 0.46 Dram1
 DNA-damage regulated autophagy modulator 1
 7012
 0.17
chr6_5287612_5288353 0.46 Pon2
 paraoxonase 2
 1086
 0.49
chr17_28007198_28009699 0.46 Anks1
 ankyrin repeat and SAM domain containing 1
 1103
 0.37
chr14_70597977_70598489 0.44 Fam160b2
 family with sequence similarity 160, member B2
 1602
 0.25
chr5_137481813_137482289 0.43 Epo
 erythropoietin
 3765
 0.1
chr6_52233543_52234485 0.43 Hoxa10
 homeobox A10
 690
 0.34
chr5_124574763_124574914 0.43 Eif2b1
 eukaryotic translation initiation factor 2B, subunit 1 (alpha)
 78
 0.94
chr13_52283527_52283880 0.42 Gm48199
 predicted gene, 48199
 103292
 0.07
chr6_114873953_114875469 0.41 Vgll4
 vestigial like family member 4
 309
 0.91
chr8_105319792_105320155 0.40 Lrrc29
 leucine rich repeat containing 29
 6286
 0.06
chr1_75137178_75137539 0.39 Cnppd1
 cyclin Pas1/PHO80 domain containing 1
 448
 0.64
chr11_116429312_116429574 0.39 Ubald2
 UBA-like domain containing 2
 4651
 0.12
chr2_27981386_27981740 0.39 Col5a1
 collagen, type V, alpha 1
 35878
 0.15
chr17_12915129_12915280 0.39 Mrpl18
 mitochondrial ribosomal protein L18
 420
 0.44
chr4_124695736_124696563 0.39 Gm24480
 predicted gene, 24480
 1458
 0.2
chr11_107471149_107471443 0.39 Pitpnc1
 phosphatidylinositol transfer protein, cytoplasmic 1
 597
 0.63
chr1_193200286_193201469 0.38 Traf3ip3
 TRAF3 interacting protein 3
 457
 0.66
chr5_111336064_111336362 0.38 Pitpnb
 phosphatidylinositol transfer protein, beta
 5406
 0.19
chr5_24425282_24425881 0.38 Slc4a2
 solute carrier family 4 (anion exchanger), member 2
 296
 0.73
chr7_16230037_16230216 0.38 Gm45409
 predicted gene 45409
 1226
 0.28
chr14_33446117_33447122 0.38 Mapk8
 mitogen-activated protein kinase 8
 523
 0.73
chr7_116031040_116032871 0.38 Sox6os
 SRY (sex determining region Y)-box 6, opposite strand
 24
 0.94
chr7_49764281_49764691 0.37 Htatip2
 HIV-1 Tat interactive protein 2
 5333
 0.23
chr10_45229498_45229649 0.37 Gm27723
 predicted gene, 27723
 17514
 0.16
chr5_130223795_130224186 0.37 Gm6598
 predicted gene 6598
 925
 0.33
chr15_12937941_12938422 0.37 Gm49100
 predicted gene, 49100
 17541
 0.19
chr19_4110129_4110280 0.37 Pitpnm1
 phosphatidylinositol transfer protein, membrane-associated 1
 277
 0.73
chr6_72392212_72392477 0.36 Vamp8
 vesicle-associated membrane protein 8
 1641
 0.22
chr11_94997390_94997735 0.36 Ppp1r9b
 protein phosphatase 1, regulatory subunit 9B
 1498
 0.25
chr2_84843620_84843993 0.36 Slc43a1
 solute carrier family 43, member 1
 3181
 0.15
chr8_34061456_34061607 0.35 Gm9951
 predicted gene 9951
 6909
 0.14
chr4_154926952_154928851 0.35 Tnfrsf14
 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
 176
 0.92
chr2_84938213_84938457 0.35 Slc43a3
 solute carrier family 43, member 3
 1445
 0.3
chr5_119628854_119629005 0.34 Tbx3os1
 T-box 3, opposite strand 1
 1336
 0.34
chr9_21029266_21030734 0.34 Icam4
 intercellular adhesion molecule 4, Landsteiner-Wiener blood group
 546
 0.46
chr13_28757451_28758760 0.34 Mir6368
 microRNA 6368
 47232
 0.14
chr18_32552663_32553082 0.33 Gypc
 glycophorin C
 7108
 0.21
chr2_33438550_33438701 0.33 Zbtb34
 zinc finger and BTB domain containing 34
 7301
 0.15
chr15_79224523_79224986 0.33 Pick1
 protein interacting with C kinase 1
 4419
 0.11
chr2_69341138_69341289 0.33 Abcb11
 ATP-binding cassette, sub-family B (MDR/TAP), member 11
 1387
 0.41
chr7_4657800_4658971 0.33 Gm44878
 predicted gene 44878
 275
 0.65
chr12_110973871_110974372 0.33 Ankrd9
 ankyrin repeat domain 9
 4134
 0.14
chr4_126261968_126262137 0.32 Trappc3
 trafficking protein particle complex 3
 273
 0.86
chr16_18342108_18342456 0.32 Tango2
 transport and golgi organization 2
 1615
 0.2
chr10_25539576_25539847 0.32 Gm29571
 predicted gene 29571
 3325
 0.21
chr17_35514558_35514964 0.31 CR974473.1
 transcription factor 19 (Tcf19) pseudogene
 1096
 0.22
chr2_31060865_31061356 0.31 Fnbp1
 formin binding protein 1
 5666
 0.19
chr17_84156320_84156518 0.31 Gm19696
 predicted gene, 19696
 7
 0.97
chr8_122658492_122658718 0.30 Cbfa2t3
 CBFA2/RUNX1 translocation partner 3
 12139
 0.09
chr6_5803273_5803424 0.30 Dync1i1
 dynein cytoplasmic 1 intermediate chain 1
 45929
 0.19
chr4_119115471_119116280 0.30 Slc2a1
 solute carrier family 2 (facilitated glucose transporter), member 1
 6961
 0.1
chr4_6196428_6196604 0.30 Ubxn2b
 UBX domain protein 2B
 5418
 0.26
chr4_133338534_133339530 0.30 Wdtc1
 WD and tetratricopeptide repeats 1
 239
 0.9
chr9_66915026_66915697 0.29 Rab8b
 RAB8B, member RAS oncogene family
 4326
 0.19
chr18_62174392_62175675 0.29 Adrb2
 adrenergic receptor, beta 2
 4926
 0.21
chr1_161750875_161751601 0.29 Gm5049
 predicted gene 5049
 5182
 0.16
chr7_81652293_81652444 0.29 Gm26149
 predicted gene, 26149
 17360
 0.12
chr5_107224079_107224230 0.29 Gm8145
 predicted gene 8145
 17469
 0.14
chr11_20022067_20022218 0.29 Spred2
 sprouty-related EVH1 domain containing 2
 67572
 0.11
chr15_103250315_103251530 0.29 Nfe2
 nuclear factor, erythroid derived 2
 543
 0.62
chr2_74663085_74663236 0.28 Evx2
 even-skipped homeobox 2
 3603
 0.08
chr1_132389425_132389838 0.27 Tmcc2
 transmembrane and coiled-coil domains 2
 687
 0.59
chr8_120454389_120454680 0.27 Gm22715
 predicted gene, 22715
 10985
 0.17
chr4_99030875_99031254 0.27 Angptl3
 angiopoietin-like 3
 110
 0.97
chr10_128821963_128822829 0.27 Sarnp
 SAP domain containing ribonucleoprotein
 464
 0.51
chr7_25088640_25088822 0.27 Mir6537
 microRNA 6537
 8444
 0.11
chr17_45886050_45887093 0.26 Gm41584
 predicted gene, 41584
 1225
 0.42
chr10_80158079_80159158 0.26 Cirbp
 cold inducible RNA binding protein
 7367
 0.08
chr1_88094712_88095046 0.26 Ugt1a7c
 UDP glucuronosyltransferase 1 family, polypeptide A7C
 183
 0.84
chr11_57649559_57650027 0.26 4933424L21Rik
 RIKEN cDNA 4933424L21 gene
 299
 0.87
chr17_79918311_79919151 0.25 Gm6552
 predicted gene 6552
 15841
 0.16
chr11_113779500_113779753 0.25 Gm11736
 predicted gene 11736
 22924
 0.14
chr4_11128483_11128667 0.25 Gm11827
 predicted gene 11827
 4617
 0.13
chr1_88095102_88096019 0.25 Ugt1a7c
 UDP glucuronosyltransferase 1 family, polypeptide A7C
 446
 0.58
chr17_24478260_24478723 0.25 Mlst8
 MTOR associated protein, LST8 homolog (S. cerevisiae)
 13
 0.93
chr4_136776404_136777015 0.25 Ephb2
 Eph receptor B2
 59134
 0.1
chr15_97785974_97786429 0.24 Slc48a1
 solute carrier family 48 (heme transporter), member 1
 1712
 0.26
chr2_74734325_74737080 0.24 Hoxd3
 homeobox D3
 813
 0.31
chr7_28307770_28307921 0.23 Timm50
 translocase of inner mitochondrial membrane 50
 173
 0.87
chr2_91027643_91027794 0.23 Gm13777
 predicted gene 13777
 3404
 0.13
chr16_7006273_7006424 0.22 Rbfox1
 RNA binding protein, fox-1 homolog (C. elegans) 1
 63498
 0.16
chr2_38925225_38926405 0.22 Nr6a1
 nuclear receptor subfamily 6, group A, member 1
 402
 0.74
chr17_83684633_83684800 0.22 Mta3
 metastasis associated 3
 21447
 0.21
chr6_88123695_88124100 0.22 Mir6376
 microRNA 6376
 19639
 0.12
chr18_37955063_37956021 0.22 Rell2
 RELT-like 2
 17
 0.88
chr13_115376228_115376379 0.22 Gm47891
 predicted gene, 47891
 94102
 0.08
chr8_57611661_57611812 0.22 Gm45534
 predicted gene 45534
 4580
 0.12
chr13_104610150_104610741 0.22 2610204G07Rik
 RIKEN cDNA 2610204G07 gene
 74486
 0.12
chr11_121548233_121548639 0.22 Tbcd
 tubulin-specific chaperone d
 1675
 0.38
chr4_130112205_130112356 0.21 Pef1
 penta-EF hand domain containing 1
 4724
 0.16
chr3_96255177_96255418 0.21 Gm20627
 predicted gene 20627
 172
 0.77
chr6_52196485_52198020 0.21 Hoxaas3
 Hoxa cluster antisense RNA 3
 3872
 0.06
chr5_125465151_125466227 0.21 Gm43756
 predicted gene 43756
 5808
 0.12
chr10_40132385_40132661 0.21 Slc16a10
 solute carrier family 16 (monocarboxylic acid transporters), member 10
 9731
 0.14
chr15_8967409_8968940 0.21 Ranbp3l
 RAN binding protein 3-like
 172
 0.96
chr4_150717290_150717441 0.21 Gm16079
 predicted gene 16079
 38573
 0.15
chr5_30920335_30921507 0.20 Khk
 ketohexokinase
 510
 0.51
chr17_29005330_29006086 0.20 Stk38
 serine/threonine kinase 38
 2018
 0.16
chr3_126365915_126366272 0.20 Arsj
 arylsulfatase J
 2409
 0.33
chr6_88925895_88926135 0.20 Gm44178
 predicted gene, 44178
 6307
 0.13
chr4_141159081_141159521 0.20 Fbxo42
 F-box protein 42
 11379
 0.12
chr7_45093013_45094086 0.20 Rcn3
 reticulocalbin 3, EF-hand calcium binding domain
 1328
 0.13
chr2_90942971_90943203 0.20 Celf1
 CUGBP, Elav-like family member 1
 2544
 0.17
chr18_21152486_21153141 0.20 Gm6378
 predicted pseudogene 6378
 75704
 0.09
chr3_95141713_95142452 0.20 Tnfaip8l2
 tumor necrosis factor, alpha-induced protein 8-like 2
 278
 0.74
chr16_86516621_86516772 0.20 Gm49572
 predicted gene, 49572
 242203
 0.02
chr11_11831905_11832402 0.20 Ddc
 dopa decarboxylase
 4127
 0.22
chr2_132518446_132518597 0.19 Gm14095
 predicted gene 14095
 17373
 0.15
chr17_29489359_29490304 0.19 Pim1
 proviral integration site 1
 922
 0.36
chr3_102152409_102152561 0.19 Casq2
 calsequestrin 2
 8434
 0.13
chr7_80628877_80629821 0.19 Crtc3
 CREB regulated transcription coactivator 3
 277
 0.89
chr8_12548291_12548587 0.19 Spaca7
 sperm acrosome associated 7
 24590
 0.14
chr14_27338331_27338622 0.19 Arhgef3
 Rho guanine nucleotide exchange factor (GEF) 3
 2410
 0.32
chr4_141286800_141287991 0.19 Gm13056
 predicted gene 13056
 8956
 0.11
chr7_27957807_27957958 0.19 Gm10651
 predicted pseudogene 10651
 8119
 0.11
chr6_48504124_48504282 0.19 Zfp862-ps
 zinc finger protein 862, pseudogene
 134
 0.91
chr19_6280905_6281787 0.19 Ehd1
 EH-domain containing 1
 4421
 0.08
chr11_55458328_55458479 0.19 Atox1
 antioxidant 1 copper chaperone
 2794
 0.16
chr16_93744711_93744862 0.18 Dop1b
 DOP1 leucine zipper like protein B
 14687
 0.16
chr11_95145006_95146328 0.18 Dlx4
 distal-less homeobox 4
 134
 0.86
chr7_141276058_141276884 0.18 Cdhr5
 cadherin-related family member 5
 303
 0.75
chr11_55077185_55077593 0.18 Ccdc69
 coiled-coil domain containing 69
 718
 0.58
chr11_61686935_61687279 0.18 Fam83g
 family with sequence similarity 83, member G
 2688
 0.23
chr18_11049995_11051717 0.18 Gata6os
 GATA binding protein 6, opposite strand
 631
 0.64
chr5_123147784_123150032 0.17 Setd1b
 SET domain containing 1B
 5951
 0.08
chr4_133041805_133043935 0.17 Ahdc1
 AT hook, DNA binding motif, containing 1
 3377
 0.24
chr13_93428749_93428900 0.17 Gm18960
 predicted gene, 18960
 7508
 0.15
chr10_91542314_91542465 0.17 Gm47084
 predicted gene, 47084
 94009
 0.08
chr5_125390257_125390622 0.17 Ubc
 ubiquitin C
 237
 0.84
chr2_170201888_170202331 0.17 Zfp217
 zinc finger protein 217
 54006
 0.14
chr3_34834735_34834886 0.17 Gm21388
 predicted gene, 21388
 2340
 0.34
chr17_40878627_40878778 0.17 9130008F23Rik
 RIKEN cDNA 9130008F23 gene
 1856
 0.26
chr2_26138540_26139205 0.16 Tmem250-ps
 transmembrane protein 250, pseudogene
 70
 0.8
chr11_96311089_96312545 0.16 Hoxb5os
 homeobox B5 and homeobox B6, opposite strand
 4907
 0.07
chr11_96790204_96790385 0.16 Cbx1
 chromobox 1
 1045
 0.36
chr10_45467792_45468248 0.16 Lin28b
 lin-28 homolog B (C. elegans)
 2181
 0.36
chr5_112344442_112344593 0.16 Hps4
 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
 1417
 0.21
chr3_84445916_84446485 0.16 Fhdc1
 FH2 domain containing 1
 7563
 0.24
chr7_110921038_110921189 0.16 Mrvi1
 MRV integration site 1
 2590
 0.25
chr6_49210050_49211632 0.16 Igf2bp3
 insulin-like growth factor 2 mRNA binding protein 3
 3320
 0.2
chr19_14426285_14426840 0.16 Tle4
 transducin-like enhancer of split 4
 168977
 0.03
chr18_61954214_61954483 0.16 Sh3tc2
 SH3 domain and tetratricopeptide repeats 2
 1264
 0.47
chr13_107074847_107075087 0.15 Gm31452
 predicted gene, 31452
 11272
 0.17
chr3_65658538_65659742 0.15 Mir8120
 microRNA 8120
 148
 0.94
chr11_69419130_69420636 0.15 Kdm6b
 KDM1 lysine (K)-specific demethylase 6B
 6208
 0.09
chr9_71213599_71213944 0.15 Aldh1a2
 aldehyde dehydrogenase family 1, subfamily A2
 2018
 0.34
chr11_95826836_95827629 0.15 Phospho1
 phosphatase, orphan 1
 2732
 0.15
chr9_65193224_65193667 0.15 Parp16
 poly (ADP-ribose) polymerase family, member 16
 1908
 0.22
chr6_84882813_84883593 0.15 Exoc6b
 exocyst complex component 6B
 10785
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Rarb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.2 0.6 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.4 GO:0061511 centriole elongation(GO:0061511)
0.1 0.3 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.1 0.5 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:0097460 ferrous iron import into cell(GO:0097460)
0.1 1.0 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.8 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.2 GO:0048793 pronephros development(GO:0048793)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.3 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1 0.3 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.7 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.0 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0036394 amylase secretion(GO:0036394)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.0 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.0 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.0 GO:0060931 sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.0 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0051029 rRNA transport(GO:0051029)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.0 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.0 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.0 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.0 GO:0030825 positive regulation of cGMP metabolic process(GO:0030825)
0.0 0.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.0 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.8 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.7 GO:0016594 glycine binding(GO:0016594)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.0 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0034902 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.0 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.0 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors