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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Relb

Z-value: 0.51

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Transcription factors associated with Relb

Gene Symbol Gene ID Gene Info
Relb
ENSMUSG00000002983.10 avian reticuloendotheliosis viral (v-rel) oncogene related B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_19628251_19629412Relb470.942289-0.497.6e-05Click!
chr7_19629476_19629768Relb1840.877869-0.461.9e-04Click!
chr7_19631359_19631510Relb19960.1574460.133.4e-01Click!
chr7_19622440_19622591Relb59190.0917790.104.6e-01Click!
chr7_19632220_19632371Relb28570.118901-0.085.2e-01Click!

Activity of the Relb motif across conditions

Conditions sorted by the z-value of the Relb motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_57320946_57324000 0.89 Hand2os1
 Hand2, opposite strand 1
 1245
 0.3
chr19_31624383_31624534 0.60 Prkg1
 protein kinase, cGMP-dependent, type I
 39912
 0.22
chr7_132270093_132270244 0.56 Chst15
 carbohydrate sulfotransferase 15
 8457
 0.18
chr10_79664388_79664620 0.54 Madcam1
 mucosal vascular addressin cell adhesion molecule 1
 55
 0.93
chr5_106457979_106459205 0.52 Barhl2
 BarH like homeobox 2
 426
 0.82
chr12_27333974_27334218 0.51 Sox11
 SRY (sex determining region Y)-box 11
 8478
 0.29
chr2_165741610_165742546 0.46 Eya2
 EYA transcriptional coactivator and phosphatase 2
 19746
 0.2
chr4_150651111_150652374 0.44 Slc45a1
 solute carrier family 45, member 1
 355
 0.88
chr11_36438334_36438485 0.44 Tenm2
 teneurin transmembrane protein 2
 6133
 0.33
chr15_102959654_102960750 0.41 Hoxc11
 homeobox C11
 5775
 0.08
chr11_44707619_44708111 0.40 Gm12158
 predicted gene 12158
 45189
 0.16
chr14_122480308_122481080 0.40 Zic2
 zinc finger protein of the cerebellum 2
 2594
 0.16
chr11_96272013_96272961 0.39 Hoxb9
 homeobox B9
 964
 0.29
chr10_42581935_42584872 0.39 Nr2e1
 nuclear receptor subfamily 2, group E, member 1
 229
 0.69
chr3_116157583_116157734 0.38 Gm26544
 predicted gene, 26544
 7179
 0.14
chr12_55321703_55321892 0.37 Prorp
 protein only RNase P catalytic subunit
 18511
 0.13
chr7_80058773_80058974 0.36 Gm21057
 predicted gene, 21057
 16374
 0.1
chr6_30544847_30545729 0.36 Cpa2
 carboxypeptidase A2, pancreatic
 803
 0.52
chr4_106976768_106976971 0.33 Ssbp3
 single-stranded DNA binding protein 3
 10443
 0.19
chr1_133050009_133050364 0.33 Pik3c2b
 phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
 4174
 0.17
chr8_61360117_61360268 0.33 Sh3rf1
 SH3 domain containing ring finger 1
 1397
 0.39
chr19_43606004_43606218 0.33 Gm20467
 predicted gene 20467
 4514
 0.13
chr4_139578966_139579453 0.32 Iffo2
 intermediate filament family orphan 2
 4489
 0.17
chr2_105125289_105128976 0.32 Wt1
 Wilms tumor 1 homolog
 78
 0.91
chr14_79290059_79290488 0.32 Rgcc
 regulator of cell cycle
 11372
 0.16
chr15_98021856_98022007 0.32 Col2a1
 collagen, type II, alpha 1
 17236
 0.13
chr10_22818712_22820254 0.31 Tcf21
 transcription factor 21
 676
 0.65
chr11_70043720_70044094 0.31 Dlg4
 discs large MAGUK scaffold protein 4
 290
 0.77
chr12_111166036_111167450 0.31 Traf3
 TNF receptor-associated factor 3
 195
 0.94
chr5_123181886_123182179 0.31 Hpd
 4-hydroxyphenylpyruvic acid dioxygenase
 35
 0.95
chr6_52202371_52204739 0.31 Hoxa5
 homeobox A5
 1032
 0.2
chr2_146834060_146838027 0.31 Gm14114
 predicted gene 14114
 3689
 0.27
chr13_73268193_73269257 0.30 Gm48000
 predicted gene, 48000
 4505
 0.18
chr16_97607830_97607981 0.28 Tmprss2
 transmembrane protease, serine 2
 3064
 0.28
chr7_80404041_80404273 0.28 Gm44851
 predicted gene 44851
 112
 0.9
chr3_78901151_78901971 0.28 Gm5277
 predicted gene 5277
 9139
 0.18
chr5_135040050_135040229 0.28 Stx1a
 syntaxin 1A (brain)
 921
 0.33
chr16_38360437_38360588 0.27 Popdc2
 popeye domain containing 2
 1697
 0.25
chr19_44755099_44757716 0.27 Pax2
 paired box 2
 362
 0.83
chr2_70558567_70559918 0.27 Gad1
 glutamate decarboxylase 1
 2800
 0.19
chr6_99200508_99201678 0.27 Foxp1
 forkhead box P1
 38075
 0.21
chr7_74006482_74006835 0.26 St8sia2
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
 7016
 0.2
chr2_180502555_180502814 0.26 Ntsr1
 neurotensin receptor 1
 2457
 0.25
chr5_75084798_75085749 0.26 Gsx2
 GS homeobox 2
 9671
 0.12
chr9_50850324_50851021 0.26 Ppp2r1b
 protein phosphatase 2, regulatory subunit A, beta
 5371
 0.16
chr9_5308602_5309732 0.26 Casp4
 caspase 4, apoptosis-related cysteine peptidase
 302
 0.91
chr18_75405225_75405894 0.26 Smad7
 SMAD family member 7
 30645
 0.18
chr13_71104368_71105400 0.25 Mir466f-4
 microRNA 466f-4
 2205
 0.39
chr14_60735927_60737075 0.25 Spata13
 spermatogenesis associated 13
 3595
 0.24
chr4_135956691_135956842 0.25 Hmgcl
 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
 2961
 0.12
chr7_35186002_35186989 0.25 Slc7a10
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
 13
 0.96
chr6_129449977_129450616 0.25 Clec1a
 C-type lectin domain family 1, member a
 1539
 0.24
chr13_83732205_83734272 0.24 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 672
 0.58
chr9_119979553_119979704 0.24 Csrnp1
 cysteine-serine-rich nuclear protein 1
 2293
 0.16
chr7_138199866_138200038 0.24 Tcerg1l
 transcription elongation regulator 1-like
 71377
 0.12
chr19_59467055_59468700 0.23 Emx2
 empty spiracles homeobox 2
 5075
 0.18
chr3_20147878_20148137 0.23 Gyg
 glycogenin
 7062
 0.21
chr17_26838158_26839992 0.22 Nkx2-5
 NK2 homeobox 5
 2490
 0.17
chr11_103770931_103772004 0.22 Wnt3
 wingless-type MMTV integration site family, member 3
 2683
 0.23
chr4_138469035_138469593 0.22 Camk2n1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
 15000
 0.15
chr9_111021840_111021991 0.22 Ltf
 lactotransferrin
 501
 0.64
chr19_55899988_55900963 0.22 Tcf7l2
 transcription factor 7 like 2, T cell specific, HMG box
 2166
 0.4
chr9_64240654_64240822 0.22 Uchl4
 ubiquitin carboxyl-terminal esterase L4
 5537
 0.1
chr7_142662290_142664788 0.22 Igf2os
 insulin-like growth factor 2, opposite strand
 1599
 0.21
chr11_32221179_32222558 0.22 Rhbdf1
 rhomboid 5 homolog 1
 376
 0.76
chr11_96306504_96308444 0.22 Hoxb5os
 homeobox B5 and homeobox B6, opposite strand
 564
 0.48
chr8_124249985_124250235 0.22 Galnt2
 polypeptide N-acetylgalactosaminyltransferase 2
 18602
 0.17
chr6_52244514_52245126 0.22 Hoxa11os
 homeobox A11, opposite strand
 423
 0.51
chr19_41699162_41699313 0.21 Slit1
 slit guidance ligand 1
 44249
 0.14
chr11_114652641_114652923 0.21 Gm11689
 predicted gene 11689
 11826
 0.16
chr19_44758783_44762005 0.21 Pax2
 paired box 2
 479
 0.75
chr5_34183436_34183719 0.21 Mxd4
 Max dimerization protein 4
 793
 0.44
chr6_125363043_125363874 0.21 Tnfrsf1a
 tumor necrosis factor receptor superfamily, member 1a
 3031
 0.17
chr2_30872666_30872817 0.21 Prrx2
 paired related homeobox 2
 6578
 0.14
chr9_79919650_79920321 0.21 Gm3211
 predicted gene 3211
 6785
 0.21
chr3_68470131_68470282 0.20 Schip1
 schwannomin interacting protein 1
 2023
 0.4
chr11_67921338_67922636 0.20 Usp43
 ubiquitin specific peptidase 43
 166
 0.74
chr7_18949615_18951696 0.20 Nova2
 NOVA alternative splicing regulator 2
 24767
 0.07
chr6_52245764_52247193 0.20 Hoxa11os
 homeobox A11, opposite strand
 257
 0.65
chr9_115391502_115391653 0.20 Gm25510
 predicted gene, 25510
 9478
 0.12
chr2_70127042_70128123 0.20 Myo3b
 myosin IIIB
 31284
 0.2
chr18_37742006_37744626 0.20 Pcdhgb6
 protocadherin gamma subfamily B, 6
 1222
 0.15
chr9_63144078_63146888 0.20 Skor1
 SKI family transcriptional corepressor 1
 1497
 0.38
chr5_75148315_75152589 0.20 Pdgfra
 platelet derived growth factor receptor, alpha polypeptide
 1840
 0.2
chr6_48025548_48025741 0.20 Zfp777
 zinc finger protein 777
 18599
 0.12
chr3_126996871_126998855 0.20 Ank2
 ankyrin 2, brain
 575
 0.63
chr15_84301565_84301928 0.19 Gm22890
 predicted gene, 22890
 21606
 0.13
chr9_44733806_44735185 0.19 Phldb1
 pleckstrin homology like domain, family B, member 1
 703
 0.43
chr2_31547915_31548066 0.19 Gm13426
 predicted gene 13426
 4705
 0.17
chr17_65905371_65905522 0.19 Gm35550
 predicted gene, 35550
 86
 0.95
chr11_118998485_119000015 0.19 Enpp7
 ectonucleotide pyrophosphatase/phosphodiesterase 7
 11034
 0.16
chr4_32923224_32923939 0.19 Ankrd6
 ankyrin repeat domain 6
 76
 0.97
chr3_38568695_38568846 0.19 Gm7824
 predicted gene 7824
 10102
 0.18
chr15_103011882_103012844 0.19 Hoxc5
 homeobox C5
 1452
 0.19
chr9_15534305_15534456 0.19 Smco4
 single-pass membrane protein with coiled-coil domains 4
 13521
 0.17
chr12_26534879_26535030 0.19 Gm46344
 predicted gene, 46344
 48163
 0.11
chr9_31120528_31120906 0.19 St14
 suppression of tumorigenicity 14 (colon carcinoma)
 11010
 0.15
chr4_149571821_149571972 0.19 Gm13066
 predicted gene 13066
 4106
 0.14
chr11_117866335_117866496 0.19 Gm11725
 predicted gene 11725
 4835
 0.1
chr19_5930278_5930429 0.19 Cdc42ep2
 CDC42 effector protein (Rho GTPase binding) 2
 5537
 0.08
chr1_130550439_130551075 0.19 Gm23623
 predicted gene, 23623
 44919
 0.1
chr8_121398391_121398555 0.19 Gm26747
 predicted gene, 26747
 22765
 0.16
chr18_37720288_37722950 0.18 Pcdhgb4
 protocadherin gamma subfamily B, 4
 1236
 0.14
chr11_45868095_45868246 0.18 Clint1
 clathrin interactor 1
 14227
 0.15
chr13_30748912_30751060 0.18 Irf4
 interferon regulatory factor 4
 679
 0.71
chr18_35627084_35627237 0.18 Slc23a1
 solute carrier family 23 (nucleobase transporters), member 1
 36
 0.94
chr4_125122525_125123430 0.18 Zc3h12a
 zinc finger CCCH type containing 12A
 457
 0.77
chr16_43303539_43303924 0.18 Gm37946
 predicted gene, 37946
 4550
 0.21
chr6_134888545_134888805 0.18 Gpr19
 G protein-coupled receptor 19
 843
 0.44
chr15_83677852_83678399 0.18 Scube1
 signal peptide, CUB domain, EGF-like 1
 17645
 0.2
chr14_101886945_101887764 0.18 Lmo7
 LIM domain only 7
 3235
 0.35
chr12_29937955_29939229 0.18 Pxdn
 peroxidasin
 542
 0.84
chr4_136031178_136031911 0.18 Rpl11
 ribosomal protein L11
 2746
 0.14
chr13_83737592_83739114 0.18 Gm33366
 predicted gene, 33366
 182
 0.66
chr4_155451781_155451950 0.17 Cfap74
 cilia and flagella associated protein 74
 295
 0.84
chr16_22161383_22162159 0.17 Igf2bp2
 insulin-like growth factor 2 mRNA binding protein 2
 321
 0.89
chr11_116194935_116195163 0.17 Acox1
 acyl-Coenzyme A oxidase 1, palmitoyl
 3680
 0.11
chr4_44694373_44694748 0.17 5730488B01Rik
 RIKEN cDNA 5730488B01 gene
 8240
 0.14
chr11_101418651_101418802 0.17 Mir6929
 microRNA 6929
 527
 0.44
chr10_79965080_79965231 0.17 Wdr18
 WD repeat domain 18
 349
 0.68
chr6_52167312_52169129 0.17 Hoxaas2
 Hoxa cluster antisense RNA 2
 290
 0.7
chr15_102950417_102951549 0.17 Hotair
 HOX transcript antisense RNA (non-protein coding)
 3253
 0.11
chr10_50895645_50896998 0.17 Sim1
 single-minded family bHLH transcription factor 1
 670
 0.79
chr3_148988258_148989425 0.17 Gm43573
 predicted gene 43573
 311
 0.63
chr7_70359645_70360747 0.17 Nr2f2
 nuclear receptor subfamily 2, group F, member 2
 275
 0.86
chr8_120833068_120833219 0.17 Gm26878
 predicted gene, 26878
 47063
 0.12
chr11_96279294_96280222 0.16 Hoxb8
 homeobox B8
 2147
 0.12
chr7_116034244_116034507 0.16 Sox6
 SRY (sex determining region Y)-box 6
 138
 0.94
chr1_133068155_133068426 0.16 Gm28609
 predicted gene 28609
 115
 0.72
chr1_75345328_75345561 0.16 Des
 desmin
 14885
 0.09
chr19_53710843_53711000 0.16 Rbm20
 RNA binding motif protein 20
 33615
 0.15
chr4_154948550_154949380 0.16 Hes5
 hes family bHLH transcription factor 5
 11958
 0.11
chr2_130638035_130638438 0.16 Lzts3
 leucine zipper, putative tumor suppressor family member 3
 141
 0.92
chr15_103002581_103003309 0.16 Hoxc6
 homeobox C6
 2416
 0.13
chr2_30074557_30074708 0.16 Pkn3
 protein kinase N3
 3052
 0.14
chr6_51320497_51320934 0.16 Gm32479
 predicted gene, 32479
 32860
 0.15
chr5_113504103_113504254 0.16 Wscd2
 WSC domain containing 2
 13426
 0.22
chr10_4080039_4080600 0.15 Gm25515
 predicted gene, 25515
 23994
 0.18
chr17_21753488_21754324 0.15 Zfp229
 zinc finger protein 229
 17994
 0.11
chr10_10546593_10546906 0.15 Rab32
 RAB32, member RAS oncogene family
 11432
 0.2
chr9_34871552_34871717 0.15 Kirrel3os
 kirre like nephrin family adhesion molecule 3, opposite strand
 57875
 0.13
chr7_70287627_70288555 0.15 Gm29327
 predicted gene 29327
 38315
 0.11
chr2_174049677_174049894 0.15 Vamp7-ps
 vesicle-associated membrane protein 7, pseudogene
 2512
 0.27
chr15_67040638_67040789 0.15 Gm31342
 predicted gene, 31342
 655
 0.76
chr4_32923966_32924256 0.15 Ankrd6
 ankyrin repeat domain 6
 606
 0.7
chr2_113757445_113759087 0.15 Grem1
 gremlin 1, DAN family BMP antagonist
 380
 0.87
chr13_56250027_56250511 0.15 Neurog1
 neurogenin 1
 1894
 0.26
chr17_79069824_79069975 0.15 Qpct
 glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
 7103
 0.18
chr18_37763101_37764236 0.15 Pcdhgb8
 protocadherin gamma subfamily B, 8
 1867
 0.09
chr11_101332029_101333108 0.15 Aoc3
 amine oxidase, copper containing 3
 1499
 0.15
chr17_29447192_29447381 0.15 Gm36199
 predicted gene, 36199
 1381
 0.3
chr2_132305611_132305762 0.15 Cds2
 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
 4390
 0.21
chr9_108296727_108297858 0.15 Amt
 aminomethyltransferase
 370
 0.7
chr1_9788025_9788203 0.15 1700034P13Rik
 RIKEN cDNA 1700034P13 gene
 4336
 0.15
chr10_18470218_18471289 0.14 Nhsl1
 NHS-like 1
 772
 0.72
chr11_95594860_95595011 0.14 Ngfr
 nerve growth factor receptor (TNFR superfamily, member 16)
 7200
 0.17
chr13_47645272_47645423 0.14 4930471G24Rik
 RIKEN cDNA 4930471G24 gene
 22203
 0.27
chr18_60649080_60649231 0.14 Synpo
 synaptopodin
 836
 0.6
chr2_10153329_10154684 0.14 Itih5
 inter-alpha (globulin) inhibitor H5
 435
 0.76
chr2_74734325_74737080 0.14 Hoxd3
 homeobox D3
 813
 0.31
chr2_6881874_6882908 0.14 Gm13389
 predicted gene 13389
 1879
 0.3
chr2_163637671_163638403 0.14 0610039K10Rik
 RIKEN cDNA 0610039K10 gene
 6813
 0.13
chr5_100358403_100358554 0.14 Gm8091
 predicted gene 8091
 3359
 0.21
chr17_34905022_34905208 0.14 Ehmt2
 euchromatic histone lysine N-methyltransferase 2
 88
 0.89
chr1_128643284_128643435 0.14 Cxcr4
 chemokine (C-X-C motif) receptor 4
 51066
 0.13
chr6_52313324_52314938 0.14 Evx1
 even-skipped homeobox 1
 579
 0.38
chr17_57148993_57149872 0.14 Cd70
 CD70 antigen
 345
 0.79
chr2_116071729_116072658 0.14 2810405F15Rik
 RIKEN cDNA 2810405F15 gene
 3903
 0.19
chr2_155380370_155380655 0.14 Trp53inp2
 transformation related protein 53 inducible nuclear protein 2
 547
 0.69
chr1_152086908_152087700 0.14 1700025G04Rik
 RIKEN cDNA 1700025G04 gene
 2666
 0.35
chr2_25213719_25213959 0.14 Stpg3
 sperm tail PG rich repeat containing 3
 188
 0.8
chr8_34325722_34326983 0.14 Gm4889
 predicted gene 4889
 1558
 0.28
chr14_31212442_31212593 0.14 Tnnc1
 troponin C, cardiac/slow skeletal
 4185
 0.12
chr15_85615061_85615935 0.14 Gm49539
 predicted gene, 49539
 30585
 0.12
chr2_18038889_18039040 0.14 A930004D18Rik
 RIKEN cDNA A930004D18 gene
 1227
 0.31
chr6_65674892_65675628 0.13 Ndnf
 neuron-derived neurotrophic factor
 3670
 0.28
chr9_4794566_4795419 0.13 Gria4
 glutamate receptor, ionotropic, AMPA4 (alpha 4)
 527
 0.88
chr1_132194845_132194996 0.13 Mir135b
 microRNA 135b
 3168
 0.14
chr1_138171970_138172121 0.13 Ptprc
 protein tyrosine phosphatase, receptor type, C
 3144
 0.18
chr17_24657836_24658944 0.13 Npw
 neuropeptide W
 67
 0.92
chr18_37690944_37692448 0.13 Pcdhgb2
 protocadherin gamma subfamily B, 2
 1861
 0.09
chr11_101965649_101967097 0.13 Sost
 sclerostin
 642
 0.52
chr3_89965873_89966024 0.13 Gm24046
 predicted gene, 24046
 2215
 0.13
chr16_69721275_69721426 0.13 4930428D20Rik
 RIKEN cDNA 4930428D20 gene
 79031
 0.12
chr7_19009114_19009265 0.13 Irf2bp1
 interferon regulatory factor 2 binding protein 1
 5145
 0.08
chr2_165233771_165234688 0.13 Cdh22
 cadherin 22
 624
 0.69
chr2_93189809_93190397 0.13 Trp53i11
 transformation related protein 53 inducible protein 11
 912
 0.64
chr10_127048288_127050177 0.13 Cyp27b1
 cytochrome P450, family 27, subfamily b, polypeptide 1
 561
 0.49
chr6_52259871_52261414 0.13 Hoxa13
 homeobox A13
 160
 0.84
chr3_89234782_89235064 0.13 Muc1
 mucin 1, transmembrane
 3452
 0.07
chr1_153048305_153048494 0.13 Nmnat2
 nicotinamide nucleotide adenylyltransferase 2
 15025
 0.19
chr19_45017873_45019099 0.13 Lzts2
 leucine zipper, putative tumor suppressor 2
 274
 0.83
chr15_91571286_91571688 0.13 Slc2a13
 solute carrier family 2 (facilitated glucose transporter), member 13
 1707
 0.3
chr13_49700528_49700679 0.13 Iars
 isoleucine-tRNA synthetase
 5203
 0.12
chr3_98283534_98283685 0.13 Hmgcs2
 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
 3174
 0.18
chr8_35699415_35699737 0.13 1700015I17Rik
 RIKEN cDNA 1700015I17 gene
 20373
 0.14
chr9_70934045_70934653 0.13 Lipc
 lipase, hepatic
 264
 0.92
chr17_28510395_28511318 0.13 Fkbp5
 FK506 binding protein 5
 501
 0.58
chr11_119237088_119237239 0.13 Ccdc40
 coiled-coil domain containing 40
 1555
 0.27
chr12_115920443_115920840 0.13 Gm42990
 predicted gene 42990
 12850
 0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Relb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1900200 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.1 0.3 GO:0060435 bronchiole development(GO:0060435)
0.1 0.2 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.1 GO:0060847 endothelial cell fate specification(GO:0060847)
0.1 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.3 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.1 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.0 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0003211 cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:2000739 regulation of mesenchymal stem cell differentiation(GO:2000739)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.0 GO:0072177 mesonephric duct development(GO:0072177)
0.0 0.1 GO:0072497 mesenchymal stem cell differentiation(GO:0072497)
0.0 0.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.1 GO:0061642 chemoattraction of axon(GO:0061642)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.0 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.0 0.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0060931 sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.0 GO:0072050 S-shaped body morphogenesis(GO:0072050)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.5 GO:0001709 cell fate determination(GO:0001709)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.0 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.0 GO:0070949 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0 0.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.0 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.0 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.0 0.0 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.1 GO:0060897 neural plate regionalization(GO:0060897)
0.0 0.1 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.1 GO:0072148 epithelial cell fate commitment(GO:0072148)
0.0 0.1 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.0 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.0 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:1902338 negative regulation of apoptotic process involved in morphogenesis(GO:1902338)
0.0 0.0 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.0 GO:0072025 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0 0.0 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.0 0.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.0 GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0005767 secondary lysosome(GO:0005767)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.1 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon