Project

ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

Navigation

Downloads

Results for Rest

Z-value: 8.44

Motif logo

Transcription factors associated with Rest

Gene Symbol	Gene ID	Gene Info
Rest Ensembl NCBI MGI UniProt	ENSMUSG00000029249.9	RE1-silencing transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_77266952_77267103	Rest	831	0.504221	-0.64	3.9e-08	Click!
chr5_77265130_77265281	Rest	286	0.861357	-0.41	1.1e-03	Click!
chr5_77267608_77267759	Rest	1487	0.294224	-0.34	7.6e-03	Click!
chr5_77267986_77268522	Rest	2058	0.220156	-0.34	7.8e-03	Click!
chr5_77246501_77246652	Rest	18915	0.115153	-0.26	4.8e-02	Click!

Activity of the Rest motif across conditions

Conditions sorted by the z-value of the Rest motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_4989098_4990412	131.56	Npas4	neuronal PAS domain protein 4	149	0.89
chr7_79501250_79502506	96.01	Mir9-3hg	Mir9-3 host gene	1757	0.18
chr19_42255346_42256673	94.37	Golga7b	golgi autoantigen, golgin subfamily a, 7B	270	0.88
chr6_127766683_127768449	92.82	Gm42738	predicted gene 42738	24	0.95
chr6_121472749_121474141	89.37	Iqsec3	IQ motif and Sec7 domain 3	178	0.95
chr2_136713069_136714459	89.10	Snap25	synaptosomal-associated protein 25	286	0.92
chr8_123413418_123414506	82.55	Tubb3	tubulin, beta 3 class III	2372	0.11
chr11_41999400_42000640	80.46	Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	336	0.92
chr2_157913335_157913704	77.06	Vstm2l	V-set and transmembrane domain containing 2-like	1134	0.51
chr2_181313043_181314281	75.01	Stmn3	stathmin-like 3	838	0.42
chr2_153031440_153032820	72.40	Xkr7	X-linked Kx blood group related 7	278	0.86
chr11_55607331_55608633	71.26	Glra1	glycine receptor, alpha 1 subunit	161	0.96
chr6_45059266_45059508	70.68	Cntnap2	contactin associated protein-like 2	30	0.98
chr19_47016270_47016724	69.68	Nt5c2	5'-nucleotidase, cytosolic II	1344	0.28
chr1_75277211_75278430	67.74	Resp18	regulated endocrine-specific protein 18	464	0.62
chr18_31446492_31447667	67.35	Syt4	synaptotagmin IV	327	0.87
chr3_114904046_114905354	64.20	Olfm3	olfactomedin 3	65	0.98
chr3_89763591_89764832	63.05	Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	397	0.76
chr16_23889696_23891150	62.05	Sst	somatostatin	535	0.77
chr1_70725543_70726581	62.02	Vwc2l	von Willebrand factor C domain-containing protein 2-like	139	0.98
chr5_116590520_116593206	59.71	Srrm4	serine/arginine repetitive matrix 4	46	0.98
chr10_11081408_11082323	58.60	Grm1	glutamate receptor, metabotropic 1	385	0.89
chr7_51621596_51622924	58.59	Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	39	0.98
chr10_6788358_6789268	58.41	Oprm1	opioid receptor, mu 1	4	0.99
chr2_163438209_163439457	58.04	Gdap1l1	ganglioside-induced differentiation-associated protein 1-like 1	300	0.84
chr1_159523756_159524611	57.90	Tnr	tenascin R	342	0.91
chr5_121009225_121009749	57.50	Rph3a	rabphilin 3A	51	0.97
chr17_91092075_91093120	57.15	Nrxn1	neurexin I	136	0.95
chr13_56895147_56895774	55.75	Trpc7	transient receptor potential cation channel, subfamily C, member 7	277	0.94
chr14_68125690_68125841	55.18	Nefm	neurofilament, medium polypeptide	919	0.55
chr8_9768980_9769453	52.99	Fam155a	family with sequence similarity 155, member A	888	0.47
chr11_116920303_116921024	52.52	Mgat5b	mannoside acetylglucosaminyltransferase 5, isoenzyme B	1800	0.3
chr10_49785211_49786117	52.21	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	2255	0.25
chr1_154723254_154724531	52.07	Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	2028	0.48
chr10_29142553_29142958	51.93	Soga3	SOGA family member 3	1084	0.4
chr1_34579671_34580338	51.73	1700101I19Rik	RIKEN cDNA 1700101I19 gene	293	0.5
chr4_15880938_15882113	49.91	Calb1	calbindin 1	259	0.9
chr1_75263068_75263858	49.16	Ptprn	protein tyrosine phosphatase, receptor type, N	444	0.62
chr17_52603559_52603710	49.16	Kcnh8	potassium voltage-gated channel, subfamily H (eag-related), member 8	925	0.44
chr18_64265796_64267074	47.69	St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	47	0.97
chr7_101421730_101422385	47.52	Pde2a	phosphodiesterase 2A, cGMP-stimulated	211	0.91
chr5_27841594_27842778	46.73	Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	37	0.97
chr9_108825632_108827025	46.48	Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	8	0.91
chr4_148286849_148288201	46.01	Disp3	dispatched RND transporter family member 3	440	0.81
chr8_55939901_55941088	45.47	Glra3	glycine receptor, alpha 3 subunit	15	0.98
chr11_102393440_102394677	45.14	Rundc3a	RUN domain containing 3A	655	0.52
chr16_75446825_75447522	44.95	Gm49678	predicted gene, 49678	120	0.98
chr11_118906575_118907024	44.46	Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3	1206	0.48
chr2_28914529_28916444	44.26	Barhl1	BarH like homeobox 1	19	0.98
chr1_74857238_74857656	44.13	Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	2513	0.16
chr7_44592789_44594513	43.22	Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	344	0.69
chrX_7638310_7639997	42.87	Syp	synaptophysin	152	0.88
chr2_28195057_28195226	42.02	Olfm1	olfactomedin 1	2048	0.37
chr7_27653599_27654745	41.69	Ttc9b	tetratricopeptide repeat domain 9B	257	0.83
chr11_4948719_4949803	41.40	Nefh	neurofilament, heavy polypeptide	1197	0.38
chr6_8948312_8949000	41.14	Nxph1	neurexophilin 1	42	0.99
chr13_23990753_23991296	40.62	Scgn	secretagogin, EF-hand calcium binding protein	190	0.91
chr14_49524944_49526079	40.56	Slc35f4	solute carrier family 35, member F4	342	0.88
chr18_35212708_35213458	39.99	Ctnna1	catenin (cadherin associated protein), alpha 1	1847	0.28
chr5_37241461_37244349	39.98	Crmp1	collapsin response mediator protein 1	171	0.95
chr16_94995704_94996004	38.92	Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	1398	0.55
chr4_101549898_101551379	38.84	Dnajc6	DnaJ heat shock protein family (Hsp40) member C6	44	0.98
chr2_164967685_164969910	38.51	Slc12a5	solute carrier family 12, member 5	516	0.7
chr2_24762057_24762224	38.22	Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	907	0.57
chr6_91839691_91840026	38.12	Grip2	glutamate receptor interacting protein 2	12608	0.15
chr3_80800286_80803016	37.75	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	928	0.67
chr4_124881258_124882719	37.69	Epha10	Eph receptor A10	1089	0.34
chr9_89737292_89737594	37.47	Ankrd34c	ankyrin repeat domain 34C	1002	0.49
chr2_70558567_70559918	37.45	Gad1	glutamate decarboxylase 1	2800	0.19
chr11_74619178_74619540	36.64	Ccdc92b	coiled-coil domain containing 92B	246	0.91
chr10_116017652_116019652	36.33	Ptprr	protein tyrosine phosphatase, receptor type, R	365	0.92
chr12_84698036_84698702	36.20	Syndig1l	synapse differentiation inducing 1 like	244	0.91
chr2_180889143_180889758	35.27	Gm14342	predicted gene 14342	210	0.87
chr9_40268795_40270233	35.11	Scn3b	sodium channel, voltage-gated, type III, beta	81	0.96
chr3_88219745_88221157	35.02	Gm3764	predicted gene 3764	2213	0.13
chr11_3774030_3775256	35.01	Osbp2	oxysterol binding protein 2	89	0.96
chr5_137030261_137030840	34.90	Vgf	VGF nerve growth factor inducible	151	0.91
chr2_25318080_25319601	34.85	Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	255	0.77
chr13_99899939_99901204	34.73	Cartpt	CART prepropeptide	70	0.98
chr2_132781102_132782201	33.91	Chgb	chromogranin B	373	0.82
chr9_49340496_49341455	33.86	Drd2	dopamine receptor D2	348	0.91
chr4_125300582_125301201	33.81	1700041M05Rik	RIKEN cDNA 1700041M05 gene	72294	0.1
chr19_22138603_22139842	33.67	Trpm3	transient receptor potential cation channel, subfamily M, member 3	105	0.98
chr7_87588060_87588319	33.65	Grm5	glutamate receptor, metabotropic 5	3791	0.35
chr17_6321918_6322069	33.31	AC183097.1	transmembrane protein 181 (TMEM181) pseudogene	257	0.85
chr9_57468140_57468355	33.02	Scamp5	secretory carrier membrane protein 5	187	0.89
chr11_78495749_78496114	32.86	Sarm1	sterile alpha and HEAT/Armadillo motif containing 1	1527	0.18
chr11_100758699_100760184	32.71	Kcnh4	potassium voltage-gated channel, subfamily H (eag-related), member 4	299	0.8
chr5_120424138_120424562	32.55	Lhx5	LIM homeobox protein 5	7349	0.14
chr17_6490728_6490879	32.03	Tmem181b-ps	transmembrane protein 181B, pseudogene	23781	0.14
chr12_70346335_70347339	31.61	Trim9	tripartite motif-containing 9	252	0.78
chr4_152286004_152287790	31.29	Hes3	hes family bHLH transcription factor 3	1708	0.23
chr1_93272441_93272828	30.81	Sned1	sushi, nidogen and EGF-like domains 1	1797	0.19
chr9_104569494_104569724	30.59	Cpne4	copine IV	126	0.98
chr7_49910058_49911168	30.49	Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	156	0.97
chr8_105693426_105694998	30.15	Carmil2	capping protein regulator and myosin 1 linker 2	852	0.36
chr12_112510243_112511522	30.11	Tmem179	transmembrane protein 179	290	0.89
chr2_180104533_180104892	30.09	Hrh3	histamine receptor H3	224	0.88
chr2_181764652_181765649	30.06	Myt1	myelin transcription factor 1	1818	0.27
chr2_109675949_109676616	29.73	Gm45346	predicted gene 45346	309	0.56
chr11_81966808_81967179	29.55	Asic2	acid-sensing (proton-gated) ion channel 2	1464	0.37
chr8_70117790_70118138	27.69	Ncan	neurocan	2909	0.11
chr17_28575220_28576027	27.48	Lhfpl5	lipoma HMGIC fusion partner-like 5	18	0.95
chr2_79453906_79455225	27.40	Neurod1	neurogenic differentiation 1	2186	0.3
chr5_33438280_33438483	27.20	Gm43851	predicted gene 43851	917	0.54
chr7_81492845_81494023	27.05	Ap3b2	adaptor-related protein complex 3, beta 2 subunit	245	0.86
chr14_124195406_124195650	26.99	Fgf14	fibroblast growth factor 14	2626	0.41
chr6_8957282_8958738	26.89	Nxph1	neurexophilin 1	8334	0.32
chr8_84946965_84947475	26.85	Rtbdn	retbindin	229	0.79
chr11_79593364_79593812	26.73	Gm23293	predicted gene, 23293	1577	0.24
chr17_72602980_72604745	26.44	Alk	anaplastic lymphoma kinase	35	0.99
chr7_44444675_44445863	26.35	Lrrc4b	leucine rich repeat containing 4B	2532	0.11
chr19_6501834_6503156	26.19	Nrxn2	neurexin II	4660	0.14
chr17_69968894_69969661	25.79	Dlgap1	DLG associated protein 1	31	0.98
chr7_44335441_44336039	25.75	Shank1	SH3 and multiple ankyrin repeat domains 1	276	0.76
chr4_155018535_155019417	25.58	Plch2	phospholipase C, eta 2	452	0.75
chr2_31641562_31642591	24.56	Gm13425	predicted gene 13425	1487	0.23
chr5_137031183_137031462	23.45	Vgf	VGF nerve growth factor inducible	621	0.54
chr8_22974876_22975667	23.09	Ank1	ankyrin 1, erythroid	135	0.96
chr17_69438821_69440200	23.02	Akain1	A kinase (PRKA) anchor inhibitor 1	184	0.52
chr1_74857699_74859071	22.73	Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	3451	0.13
chr2_155775388_155775969	22.62	Mmp24	matrix metallopeptidase 24	336	0.8
chr14_32597041_32598313	22.58	Prrxl1	paired related homeobox protein-like 1	1730	0.3
chr11_79503704_79504313	22.44	Omg	oligodendrocyte myelin glycoprotein	76	0.95
chr14_32321702_32321963	22.38	Ogdhl	oxoglutarate dehydrogenase-like	187	0.91
chr3_89159053_89160201	22.32	Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3	353	0.68
chr14_79769842_79771877	22.30	Pcdh8	protocadherin 8	345	0.74
chr7_126825279_126825959	22.23	Fam57b	family with sequence similarity 57, member B	966	0.25
chr6_39871435_39873403	21.91	Gm26833	predicted gene, 26833	448	0.58
chr2_172040251_172043672	21.73	Cbln4	cerebellin 4 precursor protein	1505	0.35
chr12_86983253_86984174	21.70	Zdhhc22	zinc finger, DHHC-type containing 22	122	0.95
chr6_113193892_113195750	21.56	Lhfpl4	lipoma HMGIC fusion partner-like protein 4	563	0.7
chr13_25269167_25270348	21.49	Nrsn1	neurensin 1	213	0.96
chr13_78171118_78171836	21.01	3110006O06Rik	RIKEN cDNA 3110006O06 gene	153	0.94
chr1_127496925_127497076	20.91	Tmem163	transmembrane protein 163	3344	0.32
chr1_175491665_175493009	20.67	Rgs7	regulator of G protein signaling 7	53	0.98
chr2_22622024_22623019	20.66	Gad2	glutamic acid decarboxylase 2	316	0.85
chr11_78952529_78952944	20.61	Lgals9	lectin, galactose binding, soluble 9	17594	0.17
chr2_178330099_178330250	20.60	Phactr3	phosphatase and actin regulator 3	2382	0.34
chr15_76721855_76722516	20.48	Lrrc24	leucine rich repeat containing 24	12	0.92
chr3_19694083_19695219	20.41	Crh	corticotropin releasing hormone	745	0.6
chr7_140922103_140923430	20.40	Nlrp6	NLR family, pyrin domain containing 6	660	0.42
chr1_72536044_72537425	20.21	Marchf4	membrane associated ring-CH-type finger 4	196	0.95
chr4_129120600_129121975	19.62	Hpca	hippocalcin	4	0.96
chr4_153482229_153483249	19.45	Ajap1	adherens junction associated protein 1	72	0.99
chr15_78712161_78713435	19.44	Elfn2	leucine rich repeat and fibronectin type III, extracellular 2	2019	0.26
chr2_180890379_180892235	19.13	Gm14342	predicted gene 14342	1647	0.19
chr2_66633862_66635239	18.88	Scn9a	sodium channel, voltage-gated, type IX, alpha	103	0.98
chr11_82434143_82435365	18.48	Tmem132e	transmembrane protein 132E	3503	0.29
chr1_81076832_81077122	18.33	Nyap2	neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2	27	0.99
chr3_103573137_103574422	18.01	Syt6	synaptotagmin VI	1452	0.38
chr2_125135832_125137073	17.88	Ctxn2	cortexin 2	181	0.91
chr5_113716630_113716816	17.87	1700069L16Rik	RIKEN cDNA 1700069L16 gene	8026	0.13
chr9_59578129_59578870	17.75	Celf6	CUGBP, Elav-like family member 6	162	0.94
chr15_84829506_84829657	17.74	Phf21b	PHD finger protein 21B	25529	0.14
chr4_127173142_127173761	17.32	Dlgap3	DLG associated protein 3	571	0.7
chr13_54750846_54750997	17.11	Gprin1	G protein-regulated inducer of neurite outgrowth 1	1047	0.39
chr2_180892979_180894605	17.06	Mir124a-3	microRNA 124a-3	248	0.53
chr3_68064789_68064954	17.06	Schip1	schwannomin interacting protein 1	69	0.99
chr11_115373706_115374845	17.01	Hid1	HID1 domain containing	6519	0.09
chr9_122117041_122117220	16.99	Snrk	SNF related kinase	136	0.93
chr1_3670464_3671619	16.83	Xkr4	X-linked Kx blood group related 4	457	0.8
chr8_106336310_106337932	16.33	Smpd3	sphingomyelin phosphodiesterase 3, neutral	867	0.61
chr12_102948664_102950014	16.31	Unc79	unc-79 homolog	215	0.92
chr6_113282134_113283787	16.19	Cpne9	copine family member IX	595	0.55
chr9_63147192_63147467	15.95	Skor1	SKI family transcriptional corepressor 1	318	0.89
chr3_87997410_87997915	15.91	Bcan	brevican	193	0.88
chr11_33680154_33680885	15.90	Kcnip1	Kv channel-interacting protein 1	52	0.97
chr15_101879968_101880119	15.83	Gm44356	predicted gene, 44356	8354	0.09
chr2_25863704_25864640	15.80	Kcnt1	potassium channel, subfamily T, member 1	204	0.9
chr11_71389623_71390092	15.77	Gm16013	predicted gene 16013	46323	0.14
chr13_42711573_42711969	15.51	Phactr1	phosphatase and actin regulator 1	2190	0.39
chr3_27370198_27370441	15.48	Ghsr	growth hormone secretagogue receptor	1032	0.59
chr15_31296980_31298102	15.19	Ankrd33b	ankyrin repeat domain 33B	10653	0.14
chr10_128668479_128668976	14.97	Ikzf4	IKAROS family zinc finger 4	631	0.47
chr2_27141741_27142940	14.80	Fam163b	family with sequence similarity 163, member B	151	0.93
chr12_113187770_113188187	14.28	Tmem121	transmembrane protein 121	2048	0.2
chr2_92401342_92401648	14.27	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	232	0.86
chr10_42574651_42575179	14.11	Nr2e1	nuclear receptor subfamily 2, group E, member 1	5430	0.21
chrX_20919797_20921410	13.78	Syn1	synapsin I	315	0.81
chr5_144542746_144543269	13.63	Nptx2	neuronal pentraxin 2	2895	0.34
chr10_45483348_45483499	13.45	Lin28b	lin-28 homolog B (C. elegans)	2354	0.33
chr2_26207818_26208366	13.31	Lhx3	LIM homeobox protein 3	197	0.88
chr8_78437765_78438492	13.00	Pou4f2	POU domain, class 4, transcription factor 2	1483	0.43
chr1_124845543_124845910	12.68	Dpp10	dipeptidylpeptidase 10	313	0.93
chr18_25752531_25753655	12.51	Celf4	CUGBP, Elav-like family member 4	401	0.88
chr3_83129655_83129889	12.47	Gm10710	predicted gene 10710	526	0.73
chr3_94580208_94580417	12.40	Snx27	sorting nexin family member 27	2237	0.15
chr1_5022752_5023448	12.21	Rgs20	regulator of G-protein signaling 20	3561	0.21
chr16_37384339_37385543	12.04	Stxbp5l	syntaxin binding protein 5-like	17	0.98
chr15_89532557_89533956	11.98	Shank3	SH3 and multiple ankyrin repeat domains 3	366	0.78
chr19_44692457_44693293	11.90	Gm26644	predicted gene, 26644	2400	0.26
chr12_116485738_116486857	11.72	Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	464	0.75
chrX_136067038_136067798	11.71	Bex2	brain expressed X-linked 2	818	0.52
chr7_27395791_27396385	11.65	Sptbn4	spectrin beta, non-erythrocytic 4	110	0.94
chr18_37687206_37687357	11.51	Pcdhga4	protocadherin gamma subfamily A, 4	397	0.52
chr18_45563646_45564226	11.50	Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	3782	0.26
chr2_143546820_143547517	10.95	Pcsk2os1	proprotein convertase subtilisin/kexin type 2, opposite strand 1	669	0.53
chr13_54371303_54372670	10.75	Cplx2	complexin 2	637	0.69
chr10_81477498_81478256	10.65	Celf5	CUGBP, Elav-like family member 5	3033	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rest

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
39.4	118.3	GO:0051385	response to mineralocorticoid(GO:0051385)
23.0	68.9	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
22.2	66.7	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
18.0	54.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
17.5	52.6	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
16.6	82.9	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
16.3	49.0	GO:0033693	neurofilament bundle assembly(GO:0033693)
16.3	146.3	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
15.9	47.6	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
15.5	46.5	GO:0097503	sialylation(GO:0097503)
12.6	37.8	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
12.1	36.3	GO:0021586	pons maturation(GO:0021586)
11.6	46.5	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
11.1	33.3	GO:0038128	ERBB2 signaling pathway(GO:0038128)
11.0	33.1	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
11.0	33.0	GO:0072318	clathrin coat disassembly(GO:0072318)
10.9	43.7	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
10.6	42.5	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
9.3	74.5	GO:0071420	cellular response to histamine(GO:0071420)
8.2	32.9	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
6.9	55.4	GO:0071257	cellular response to electrical stimulus(GO:0071257)
6.6	26.6	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
6.3	18.9	GO:1902075	cellular response to salt(GO:1902075)
5.7	85.9	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
5.6	152.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
5.3	21.2	GO:0046959	habituation(GO:0046959)
5.1	25.4	GO:0070842	aggresome assembly(GO:0070842)
4.8	33.6	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
4.5	31.6	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
4.4	17.5	GO:0006538	glutamate catabolic process(GO:0006538)
4.3	21.4	GO:0000160	phosphorelay signal transduction system(GO:0000160)
4.1	24.8	GO:0090273	regulation of somatostatin secretion(GO:0090273)
3.8	49.5	GO:0001553	luteinization(GO:0001553)
3.7	45.0	GO:0007614	short-term memory(GO:0007614)
3.7	11.1	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
3.6	7.3	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
3.4	10.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
3.4	26.9	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
3.3	56.6	GO:0001504	neurotransmitter uptake(GO:0001504)
3.3	3.3	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
3.2	44.4	GO:0043084	penile erection(GO:0043084)
3.1	12.3	GO:0007258	JUN phosphorylation(GO:0007258)
3.0	3.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
2.9	11.6	GO:0021523	somatic motor neuron differentiation(GO:0021523)
2.8	22.5	GO:0071625	vocalization behavior(GO:0071625)
2.7	93.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
2.7	10.9	GO:0023041	neuronal signal transduction(GO:0023041)
2.7	32.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
2.6	41.7	GO:0006828	manganese ion transport(GO:0006828)
2.4	7.3	GO:0021558	trochlear nerve development(GO:0021558)
2.4	26.4	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
2.3	11.7	GO:0050915	sensory perception of sour taste(GO:0050915)
2.3	13.5	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
2.3	11.3	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
2.2	26.5	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
2.2	11.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
2.2	19.6	GO:0046085	adenosine metabolic process(GO:0046085)
2.1	19.1	GO:0044331	cell-cell adhesion mediated by cadherin(GO:0044331)
2.0	14.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
2.0	21.9	GO:0033574	response to testosterone(GO:0033574)
1.9	1.9	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.9	9.6	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
1.9	15.2	GO:0048149	behavioral response to ethanol(GO:0048149)
1.8	22.1	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
1.8	3.6	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
1.8	9.0	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
1.7	29.5	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
1.7	12.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
1.7	6.7	GO:0021559	trigeminal nerve development(GO:0021559)
1.7	70.3	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
1.6	4.9	GO:1904430	negative regulation of t-circle formation(GO:1904430)
1.6	1.6	GO:0070092	regulation of glucagon secretion(GO:0070092)
1.6	61.6	GO:0042462	eye photoreceptor cell development(GO:0042462)
1.6	3.1	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.5	10.7	GO:0002091	negative regulation of receptor internalization(GO:0002091)
1.4	23.0	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.4	18.0	GO:0045760	positive regulation of action potential(GO:0045760)
1.4	44.1	GO:0030901	midbrain development(GO:0030901)
1.3	5.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.3	19.5	GO:0048266	behavioral response to pain(GO:0048266)
1.2	22.3	GO:0072661	protein targeting to plasma membrane(GO:0072661)
1.2	6.1	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
1.2	6.0	GO:0035740	CD8-positive, alpha-beta T cell proliferation(GO:0035740)
1.2	3.5	GO:0030070	insulin processing(GO:0030070)
1.2	3.5	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
1.1	4.5	GO:0010587	miRNA catabolic process(GO:0010587)
1.1	6.4	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
1.0	6.1	GO:0014824	artery smooth muscle contraction(GO:0014824)
1.0	4.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
1.0	5.0	GO:0007256	activation of JNKK activity(GO:0007256)
1.0	32.6	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
1.0	3.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
1.0	48.3	GO:0006749	glutathione metabolic process(GO:0006749)
1.0	9.6	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
1.0	43.2	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.9	3.8	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.9	22.7	GO:0010107	potassium ion import(GO:0010107)
0.9	8.4	GO:0070255	regulation of mucus secretion(GO:0070255)
0.9	37.0	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.9	1.8	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.9	4.5	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.9	2.6	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.9	1.7	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.8	19.4	GO:0018345	protein palmitoylation(GO:0018345)
0.8	2.5	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.8	3.3	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.8	1.7	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.8	13.0	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.8	0.8	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.8	3.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.8	33.4	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.7	2.2	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.7	19.7	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.7	2.9	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.7	2.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.7	2.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.7	2.1	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.7	2.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.7	1.4	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.7	2.0	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.7	2.0	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.7	1.3	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.7	4.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.7	2.6	GO:2000650	negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.7	2.6	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.7	1.3	GO:0002434	immune complex clearance(GO:0002434)
0.7	2.0	GO:0015747	urate transport(GO:0015747)
0.6	1.3	GO:0061549	noradrenergic neuron development(GO:0003358) sympathetic ganglion development(GO:0061549)
0.6	8.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.6	0.6	GO:0070428	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.6	1.9	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.6	1.2	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6	2.4	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.6	1.8	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.6	3.5	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.6	1.7	GO:0034436	glycoprotein transport(GO:0034436)
0.6	1.7	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.6	19.4	GO:0007269	neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.5	2.2	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.5	3.8	GO:0048733	sebaceous gland development(GO:0048733)
0.5	2.2	GO:0008343	adult feeding behavior(GO:0008343)
0.5	1.1	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.5	0.5	GO:0036514	dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.5	13.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.5	2.0	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.5	12.6	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5	7.5	GO:0035418	protein localization to synapse(GO:0035418)
0.5	2.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.5	2.0	GO:0006742	NADP catabolic process(GO:0006742)
0.5	3.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.5	1.0	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.5	1.4	GO:0070375	ERK5 cascade(GO:0070375)
0.5	25.7	GO:0042391	regulation of membrane potential(GO:0042391)
0.5	1.4	GO:1900368	regulation of RNA interference(GO:1900368)
0.5	20.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.5	0.9	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.5	2.8	GO:0007220	Notch receptor processing(GO:0007220)
0.5	3.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.4	1.8	GO:0070459	prolactin secretion(GO:0070459)
0.4	3.9	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.4	0.9	GO:0048865	stem cell fate commitment(GO:0048865)
0.4	1.7	GO:0061074	regulation of neural retina development(GO:0061074)
0.4	5.6	GO:0045116	protein neddylation(GO:0045116)
0.4	0.9	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.4	1.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.4	0.8	GO:0032763	regulation of mast cell cytokine production(GO:0032763)
0.4	3.7	GO:0060539	diaphragm development(GO:0060539)
0.4	0.4	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.4	1.2	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.4	4.8	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.4	11.6	GO:0021766	hippocampus development(GO:0021766)
0.4	0.8	GO:0072205	metanephric collecting duct development(GO:0072205)
0.4	0.4	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.4	2.4	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4	2.0	GO:0060179	male mating behavior(GO:0060179)
0.4	27.3	GO:0000187	activation of MAPK activity(GO:0000187)
0.4	0.8	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.4	0.8	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.4	0.8	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.4	1.5	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.4	1.9	GO:0050942	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.4	36.4	GO:0043524	negative regulation of neuron apoptotic process(GO:0043524)
0.4	0.4	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.4	1.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.4	0.7	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.4	32.6	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.4	10.5	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.4	0.7	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4	1.4	GO:0071034	nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.4	1.4	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4	1.4	GO:0016584	nucleosome positioning(GO:0016584)
0.3	1.0	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.3	1.4	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3	20.0	GO:0014065	phosphatidylinositol 3-kinase signaling(GO:0014065)
0.3	3.0	GO:0001964	startle response(GO:0001964)
0.3	24.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3	1.3	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.3	1.0	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.3	1.3	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.3	1.0	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.3	1.6	GO:0048318	axial mesoderm development(GO:0048318)
0.3	1.0	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.3	0.9	GO:0060988	lipid tube assembly(GO:0060988)
0.3	0.3	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.3	1.2	GO:0007413	axonal fasciculation(GO:0007413)
0.3	2.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3	1.5	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.3	0.6	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.3	0.3	GO:0007228	positive regulation of hh target transcription factor activity(GO:0007228)
0.3	0.6	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.3	2.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.3	0.9	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.3	1.2	GO:0015867	ATP transport(GO:0015867)
0.3	1.8	GO:0015884	folic acid transport(GO:0015884)
0.3	2.3	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.3	0.8	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.3	0.8	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.3	1.1	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.3	0.8	GO:0060178	regulation of exocyst localization(GO:0060178)
0.3	0.8	GO:0006566	threonine metabolic process(GO:0006566)
0.3	0.5	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.3	1.6	GO:0001842	neural fold formation(GO:0001842)
0.3	1.6	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.3	1.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.3	15.6	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.3	0.8	GO:0015889	cobalamin transport(GO:0015889)
0.3	1.0	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3	1.3	GO:0033136	serine phosphorylation of STAT3 protein(GO:0033136)
0.3	0.8	GO:0021796	cerebral cortex regionalization(GO:0021796) telencephalon regionalization(GO:0021978)
0.3	22.7	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
0.3	2.3	GO:0042438	melanin biosynthetic process(GO:0042438)
0.3	16.6	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.3	0.5	GO:0043615	astrocyte cell migration(GO:0043615)
0.3	0.3	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.3	0.5	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.2	0.2	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2	1.2	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.2	3.4	GO:0007340	acrosome reaction(GO:0007340)
0.2	3.0	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.2	0.2	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.2	1.2	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2	0.5	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2	1.7	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.2	0.7	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.2	0.5	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.2	0.5	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2	2.3	GO:0048268	clathrin coat assembly(GO:0048268)
0.2	3.0	GO:0003323	type B pancreatic cell development(GO:0003323)
0.2	0.9	GO:0032808	lacrimal gland development(GO:0032808)
0.2	0.7	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.2	0.7	GO:0042126	nitrate metabolic process(GO:0042126)
0.2	0.2	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.2	4.5	GO:0048665	neuron fate specification(GO:0048665)
0.2	34.1	GO:0007286	spermatid development(GO:0007286)
0.2	0.4	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2	3.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.2	0.7	GO:0031017	exocrine pancreas development(GO:0031017)
0.2	3.3	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2	0.7	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.2	5.0	GO:0008306	associative learning(GO:0008306)
0.2	0.2	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.2	0.2	GO:0018196	peptidyl-asparagine modification(GO:0018196)
0.2	0.9	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
0.2	0.4	GO:0042637	catagen(GO:0042637)
0.2	0.4	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2	2.5	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.2	0.6	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.2	0.2	GO:0071870	cellular response to catecholamine stimulus(GO:0071870)
0.2	0.6	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.2	0.8	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.2	1.0	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.2	13.2	GO:0006821	chloride transport(GO:0006821)
0.2	6.2	GO:0009749	response to glucose(GO:0009749)
0.2	0.2	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.2	0.8	GO:0045792	negative regulation of cell size(GO:0045792)
0.2	0.6	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	0.4	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2	0.4	GO:0010046	response to mycotoxin(GO:0010046)
0.2	0.2	GO:1904023	regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.2	0.8	GO:0042506	tyrosine phosphorylation of Stat5 protein(GO:0042506)
0.2	0.4	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.2	0.6	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.2	0.7	GO:0050957	equilibrioception(GO:0050957)
0.2	1.3	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2	1.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.2	0.4	GO:0043570	meiotic mismatch repair(GO:0000710) maintenance of DNA repeat elements(GO:0043570)
0.2	5.4	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.2	0.4	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.2	0.2	GO:2000316	regulation of T-helper 17 type immune response(GO:2000316)
0.2	0.5	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.2	0.7	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.2	1.4	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.2	0.2	GO:0097466	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.2	0.4	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.2	22.6	GO:0051480	regulation of cytosolic calcium ion concentration(GO:0051480)
0.2	0.2	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.2	0.7	GO:0034433	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.2	0.3	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.2	0.3	GO:0060460	left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.2	1.6	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2	0.7	GO:0014003	oligodendrocyte development(GO:0014003)
0.2	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2	4.6	GO:0002088	lens development in camera-type eye(GO:0002088)
0.2	0.2	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.2	0.3	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.2	0.8	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.2	0.5	GO:0042256	mature ribosome assembly(GO:0042256)
0.2	1.3	GO:0043129	surfactant homeostasis(GO:0043129)
0.2	46.0	GO:0001701	in utero embryonic development(GO:0001701)
0.2	7.6	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.2	1.3	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.2	0.2	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2	19.2	GO:0010506	regulation of autophagy(GO:0010506)
0.2	1.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.2	0.8	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.2	1.0	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
0.2	1.3	GO:1901984	negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.2	0.6	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	0.3	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2	2.8	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.2	1.4	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.2	1.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	1.2	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	1.0	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.1	0.6	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	0.1	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1	1.0	GO:0071493	cellular response to UV-B(GO:0071493)
0.1	0.6	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1	0.6	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.1	0.4	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.1	0.6	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.3	GO:0042360	vitamin E metabolic process(GO:0042360)
0.1	0.4	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.1	0.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	0.1	GO:0090148	membrane fission(GO:0090148)
0.1	0.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	0.4	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	0.3	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.1	0.1	GO:0060931	sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.1	4.4	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.1	5.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	1.0	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.5	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.1	0.6	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.3	GO:0097062	dendritic spine maintenance(GO:0097062)
0.1	1.7	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	0.6	GO:0034227	tRNA thio-modification(GO:0034227)
0.1	0.9	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.1	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.1	1.9	GO:0019233	sensory perception of pain(GO:0019233)
0.1	1.8	GO:0045109	intermediate filament organization(GO:0045109)
0.1	0.2	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.7	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	1.6	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.1	0.4	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1	0.6	GO:0048515	spermatid differentiation(GO:0048515)
0.1	0.7	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.1	0.2	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.1	0.6	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.1	0.2	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.1	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	2.6	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.1	0.2	GO:0010713	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.1	0.2	GO:0048520	positive regulation of behavior(GO:0048520)
0.1	0.6	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.1	1.5	GO:0006836	neurotransmitter transport(GO:0006836)
0.1	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	9.3	GO:0007160	cell-matrix adhesion(GO:0007160)
0.1	0.3	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.1	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.1	0.2	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1	3.1	GO:0043467	regulation of generation of precursor metabolites and energy(GO:0043467)
0.1	0.2	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.1	0.2	GO:0023035	CD40 signaling pathway(GO:0023035)
0.1	0.8	GO:1990173	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1	0.1	GO:0048290	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.1	0.9	GO:0009251	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1	47.4	GO:0007267	cell-cell signaling(GO:0007267)
0.1	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.2	GO:0042414	epinephrine metabolic process(GO:0042414)
0.1	0.3	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1	1.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	0.3	GO:0045990	carbon catabolite regulation of transcription(GO:0045990)
0.1	0.2	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.1	2.1	GO:0046324	regulation of glucose import(GO:0046324)
0.1	5.2	GO:0031333	negative regulation of protein complex assembly(GO:0031333)
0.1	0.2	GO:0055075	potassium ion homeostasis(GO:0055075)
0.1	0.4	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1	0.3	GO:0071354	response to interleukin-6(GO:0070741) cellular response to interleukin-6(GO:0071354)
0.1	0.2	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.3	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1	0.3	GO:0048566	embryonic digestive tract development(GO:0048566)
0.1	0.2	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	0.3	GO:0046655	folic acid metabolic process(GO:0046655)
0.1	0.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.4	GO:0002070	epithelial cell maturation(GO:0002070)
0.1	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	0.7	GO:0015858	nucleoside transport(GO:0015858)
0.1	0.7	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.3	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1	0.7	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.6	GO:1990403	embryonic brain development(GO:1990403)
0.1	0.3	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.4	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.1	0.4	GO:0044065	regulation of respiratory system process(GO:0044065)
0.1	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.1	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1	1.6	GO:0031929	TOR signaling(GO:0031929)
0.1	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.5	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.1	0.5	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1	0.7	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.1	0.1	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	0.2	GO:0042908	xenobiotic transport(GO:0042908)
0.1	0.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.1	0.1	GO:0019364	pyridine nucleotide catabolic process(GO:0019364)
0.1	3.2	GO:0030316	osteoclast differentiation(GO:0030316)
0.1	2.2	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	3.0	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	1.0	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1	0.4	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.1	0.2	GO:0042220	response to cocaine(GO:0042220)
0.1	1.7	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.1	0.3	GO:0051602	response to electrical stimulus(GO:0051602)
0.1	0.1	GO:0071839	apoptotic process in bone marrow(GO:0071839) regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.1	0.1	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087)
0.1	0.2	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
0.1	22.1	GO:0006812	cation transport(GO:0006812)
0.1	1.1	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	0.4	GO:0009651	response to salt stress(GO:0009651)
0.1	0.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.2	GO:0071320	cellular response to cAMP(GO:0071320)
0.1	1.2	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.1	0.7	GO:0043507	positive regulation of JUN kinase activity(GO:0043507)
0.1	0.2	GO:0045581	negative regulation of T cell differentiation(GO:0045581)
0.1	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.1	0.4	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1	0.5	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.2	GO:0040031	snRNA modification(GO:0040031)
0.1	0.7	GO:0035307	positive regulation of protein dephosphorylation(GO:0035307)
0.1	0.2	GO:0019086	late viral transcription(GO:0019086)
0.1	0.2	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.1	0.2	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	0.1	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) endocardial cushion to mesenchymal transition(GO:0090500)
0.1	0.1	GO:0002636	positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1	0.1	GO:0006116	NADH oxidation(GO:0006116)
0.1	0.1	GO:0071071	regulation of phospholipid biosynthetic process(GO:0071071) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.1	0.1	GO:0010574	regulation of vascular endothelial growth factor production(GO:0010574)
0.1	0.4	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.1	3.2	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.1	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.5	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.1	0.5	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	1.6	GO:0030516	regulation of axon extension(GO:0030516)
0.1	0.1	GO:0010224	response to UV-B(GO:0010224)
0.1	0.3	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1	0.2	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1	0.1	GO:0072553	terminal button organization(GO:0072553)
0.1	0.7	GO:0006303	non-recombinational repair(GO:0000726) double-strand break repair via nonhomologous end joining(GO:0006303)
0.1	0.1	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.1	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1	0.1	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.1	GO:1902019	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1	0.2	GO:0032482	Rab protein signal transduction(GO:0032482)
0.1	0.8	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.6	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.2	GO:0000032	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.1	0.2	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1	1.2	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.1	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.1	0.9	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1	0.1	GO:0042048	olfactory behavior(GO:0042048)
0.1	0.2	GO:0090042	tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.1	0.7	GO:0051205	protein insertion into membrane(GO:0051205)
0.1	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.1	GO:1901977	negative regulation of cell cycle checkpoint(GO:1901977)
0.1	0.2	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.1	0.1	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.1	0.4	GO:0044458	motile cilium assembly(GO:0044458)
0.1	0.2	GO:0006553	lysine metabolic process(GO:0006553)
0.1	1.0	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.1	0.1	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.1	0.1	GO:0060717	chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.1	1.1	GO:0007032	endosome organization(GO:0007032)
0.1	0.5	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1	0.2	GO:0035588	G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.3	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.2	GO:1900543	negative regulation of purine nucleotide metabolic process(GO:1900543)
0.1	0.6	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1	0.7	GO:0031648	protein destabilization(GO:0031648)
0.1	0.1	GO:0090365	regulation of mRNA modification(GO:0090365)
0.1	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.1	GO:2000399	negative regulation of thymocyte aggregation(GO:2000399)
0.1	0.1	GO:0046104	thymidine metabolic process(GO:0046104)
0.1	0.2	GO:0042732	D-xylose metabolic process(GO:0042732)
0.1	0.4	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.1	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	1.0	GO:0046785	microtubule polymerization(GO:0046785)
0.1	0.9	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.1	GO:0008078	mesodermal cell migration(GO:0008078)
0.1	0.8	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1	0.1	GO:0090343	positive regulation of cell aging(GO:0090343)
0.1	0.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.1	GO:0052428	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) negative regulation by host of symbiont molecular function(GO:0052405) modulation by host of symbiont catalytic activity(GO:0052422) modification by host of symbiont molecular function(GO:0052428)
0.1	0.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.1	0.1	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1	0.1	GO:0016237	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.1	0.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.5	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0060850	regulation of transcription involved in cell fate commitment(GO:0060850)
0.0	0.3	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0	0.0	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.5	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.0	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.1	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0098762	meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.0	0.1	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	2.1	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	1.4	GO:0046632	alpha-beta T cell differentiation(GO:0046632)
0.0	0.1	GO:0072506	cellular phosphate ion homeostasis(GO:0030643) phosphate ion homeostasis(GO:0055062) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) trivalent inorganic anion homeostasis(GO:0072506)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.6	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.5	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.3	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.6	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.0	GO:0045980	negative regulation of nucleotide metabolic process(GO:0045980)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	1.2	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.1	GO:1903044	protein localization to membrane raft(GO:1903044)
0.0	0.3	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.0	GO:0032048	cardiolipin metabolic process(GO:0032048)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0	0.4	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.4	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0	0.1	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.4	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.2	GO:0048246	macrophage chemotaxis(GO:0048246)
0.0	0.1	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.1	GO:0018377	protein myristoylation(GO:0018377)
0.0	0.7	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0002035	regulation of blood volume by renin-angiotensin(GO:0002016) brain renin-angiotensin system(GO:0002035)
0.0	0.2	GO:0003170	heart valve development(GO:0003170)
0.0	0.0	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.0	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	0.1	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.0	0.1	GO:0030262	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0	0.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.0	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	1.8	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.2	GO:0032620	interleukin-17 production(GO:0032620)
0.0	0.2	GO:0001967	suckling behavior(GO:0001967)
0.0	0.1	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.0	GO:0019230	proprioception(GO:0019230) sensory neuron axon guidance(GO:0097374)
0.0	0.1	GO:0042461	photoreceptor cell development(GO:0042461)
0.0	0.2	GO:0030728	ovulation(GO:0030728)
0.0	0.2	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.5	GO:0022900	electron transport chain(GO:0022900)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0060355	regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.2	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.0	0.3	GO:0008361	regulation of cell size(GO:0008361)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928) negative regulation of superoxide anion generation(GO:0032929)
0.0	0.0	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.2	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.0	0.2	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.3	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0060074	synapse maturation(GO:0060074)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.2	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0014002	astrocyte development(GO:0014002)
0.0	0.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0006101	citrate metabolic process(GO:0006101)
0.0	0.1	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.1	GO:2000194	regulation of female gonad development(GO:2000194)
0.0	0.3	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.0	0.0	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.0	0.4	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.0	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.0	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.1	GO:0006119	oxidative phosphorylation(GO:0006119)
0.0	0.3	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:1902808	positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.2	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.2	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.0	GO:0031281	positive regulation of cyclase activity(GO:0031281)
0.0	3.5	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.0	0.4	GO:0046330	positive regulation of JNK cascade(GO:0046330)
0.0	0.1	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.4	GO:1901216	positive regulation of neuron death(GO:1901216)
0.0	0.0	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.0	GO:0097421	liver regeneration(GO:0097421)
0.0	0.0	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.0	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.2	GO:1901655	cellular response to ketone(GO:1901655)
0.0	0.1	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.0	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0010039	response to iron ion(GO:0010039)
0.0	1.2	GO:0048511	rhythmic process(GO:0048511)
0.0	0.0	GO:0030718	germ-line stem cell population maintenance(GO:0030718) cell quiescence(GO:0044838)
0.0	0.0	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:1990138	neuron projection extension(GO:1990138)
0.0	0.0	GO:0034332	adherens junction organization(GO:0034332)
0.0	0.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0072497	mesenchymal stem cell differentiation(GO:0072497) regulation of mesenchymal stem cell differentiation(GO:2000739)
0.0	0.2	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.1	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.7	GO:0034599	cellular response to oxidative stress(GO:0034599)
0.0	0.4	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.0	0.2	GO:0098792	xenophagy(GO:0098792)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366) positive regulation of hepatocyte differentiation(GO:0070368)
0.0	0.1	GO:0009445	putrescine metabolic process(GO:0009445)
0.0	0.2	GO:0045687	positive regulation of glial cell differentiation(GO:0045687)
0.0	0.3	GO:1901998	toxin transport(GO:1901998)
0.0	0.1	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.2	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.0	GO:0007135	meiosis II(GO:0007135) meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0	0.0	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.3	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.1	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.6	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.1	GO:0038179	neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0	0.0	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.3	GO:0009072	aromatic amino acid family metabolic process(GO:0009072)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.7	GO:0050954	sensory perception of mechanical stimulus(GO:0050954)
0.0	0.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:1901985	positive regulation of protein acetylation(GO:1901985)
0.0	0.0	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.3	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0048017	inositol lipid-mediated signaling(GO:0048017)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0009268	response to pH(GO:0009268)
0.0	0.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.0	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.0	0.0	GO:0099558	motor learning(GO:0061743) maintenance of synapse structure(GO:0099558)
0.0	0.2	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.0	GO:0051342	protein maturation by protein folding(GO:0022417) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.0	GO:1901970	positive regulation of mitotic sister chromatid separation(GO:1901970)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.0	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.0	GO:0043485	endosome to melanosome transport(GO:0035646) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0	0.1	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.0	GO:0048484	enteric nervous system development(GO:0048484)
0.0	0.6	GO:0034220	ion transmembrane transport(GO:0034220)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:0006020	inositol metabolic process(GO:0006020)
0.0	1.0	GO:0000423	macromitophagy(GO:0000423)
0.0	0.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.0	GO:0043486	histone exchange(GO:0043486)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0035902	response to immobilization stress(GO:0035902)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.2	GO:0007140	male meiosis(GO:0007140)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0009409	response to cold(GO:0009409)
0.0	0.1	GO:0014741	negative regulation of muscle hypertrophy(GO:0014741)
0.0	0.0	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.6	GO:0009062	fatty acid catabolic process(GO:0009062)
0.0	0.1	GO:0033555	multicellular organismal response to stress(GO:0033555)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.0	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0010934	macrophage cytokine production(GO:0010934)
0.0	0.0	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.0	0.0	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.0	0.1	GO:2000479	regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0	0.0	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	0.1	GO:0006415	translational termination(GO:0006415)
0.0	0.0	GO:1905154	negative regulation of membrane invagination(GO:1905154)
0.0	0.2	GO:0098840	intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0072643	interferon-gamma secretion(GO:0072643)
0.0	0.0	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.0	GO:0032799	low-density lipoprotein receptor particle metabolic process(GO:0032799)
0.0	0.0	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0	0.1	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.3	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.0	0.1	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.2	GO:0006284	base-excision repair(GO:0006284)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.0	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.0	GO:0015698	inorganic anion transport(GO:0015698)
0.0	0.0	GO:0030823	regulation of cGMP metabolic process(GO:0030823)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.0	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.1	GO:1903321	negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0	0.0	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.0	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0	0.0	GO:0009211	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.0	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0	0.0	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.0	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0	0.0	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.0	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.0	GO:0090239	regulation of histone H4 acetylation(GO:0090239)
0.0	0.0	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.0	0.0	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.0	0.1	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.0	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.0	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0003207	cardiac chamber formation(GO:0003207)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.3	89.2	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
18.2	54.5	GO:0072534	perineuronal net(GO:0072534)
17.3	52.0	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
13.3	252.6	GO:0060077	inhibitory synapse(GO:0060077)
7.8	46.5	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
7.5	15.1	GO:0044316	cone cell pedicle(GO:0044316)
7.4	44.6	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
7.0	126.1	GO:0030673	axolemma(GO:0030673)
6.9	62.3	GO:0005883	neurofilament(GO:0005883)
5.9	190.1	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
5.4	64.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
5.1	143.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
4.9	58.3	GO:0031045	dense core granule(GO:0031045)
4.8	87.1	GO:0032839	dendrite cytoplasm(GO:0032839)
4.3	52.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
3.3	33.0	GO:0044292	dendrite terminus(GO:0044292)
3.3	19.8	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
3.1	9.4	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
3.0	48.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
2.9	23.3	GO:1904115	axon cytoplasm(GO:1904115)
2.8	110.7	GO:0042734	presynaptic membrane(GO:0042734)
2.8	11.1	GO:0008091	spectrin(GO:0008091)
2.6	50.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
2.3	34.9	GO:0097440	apical dendrite(GO:0097440)
2.2	26.7	GO:0032426	stereocilium tip(GO:0032426)
1.9	11.2	GO:0005915	zonula adherens(GO:0005915)
1.7	52.4	GO:0005801	cis-Golgi network(GO:0005801)
1.7	10.0	GO:0000137	Golgi cis cisterna(GO:0000137)
1.6	62.1	GO:0043198	dendritic shaft(GO:0043198)
1.4	57.4	GO:0034707	chloride channel complex(GO:0034707)
1.4	7.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
1.4	37.9	GO:0031941	filamentous actin(GO:0031941)
1.3	114.2	GO:0043204	perikaryon(GO:0043204)
1.2	3.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
1.2	21.8	GO:0032809	neuronal cell body membrane(GO:0032809)
1.0	45.3	GO:0030173	integral component of Golgi membrane(GO:0030173)
1.0	1.0	GO:0097513	myosin II filament(GO:0097513)
1.0	90.0	GO:0043679	axon terminus(GO:0043679)
0.9	12.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.9	42.4	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.8	9.1	GO:0061702	inflammasome complex(GO:0061702)
0.8	2.4	GO:0035061	interchromatin granule(GO:0035061)
0.8	1.6	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.8	1.6	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.7	34.3	GO:0030667	secretory granule membrane(GO:0030667)
0.7	2.1	GO:0005745	m-AAA complex(GO:0005745)
0.7	2.0	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.6	11.6	GO:0031201	SNARE complex(GO:0031201)
0.6	61.9	GO:0045211	postsynaptic membrane(GO:0045211)
0.6	1.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.6	1.7	GO:0071001	U4/U6 snRNP(GO:0071001)
0.5	2.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.5	5.6	GO:0035102	PRC1 complex(GO:0035102)
0.5	0.5	GO:0032437	cuticular plate(GO:0032437)
0.5	3.0	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5	2.8	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5	1.8	GO:0071203	WASH complex(GO:0071203)
0.5	150.9	GO:0045202	synapse(GO:0045202)
0.4	4.6	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.4	144.8	GO:0005667	transcription factor complex(GO:0005667)
0.4	0.8	GO:0042583	chromaffin granule(GO:0042583)
0.4	1.6	GO:0019815	B cell receptor complex(GO:0019815)
0.4	2.7	GO:0031931	TORC1 complex(GO:0031931)
0.4	25.7	GO:0030426	growth cone(GO:0030426)
0.4	68.6	GO:0030141	secretory granule(GO:0030141)
0.4	1.5	GO:0032133	chromosome passenger complex(GO:0032133)
0.4	38.4	GO:0030424	axon(GO:0030424)
0.4	0.7	GO:0030314	junctional membrane complex(GO:0030314)
0.4	1.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.3	4.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.3	49.6	GO:0043005	neuron projection(GO:0043005)
0.3	1.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.3	1.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.3	1.7	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.3	0.3	GO:0016600	flotillin complex(GO:0016600)
0.3	3.5	GO:0055038	recycling endosome membrane(GO:0055038)
0.3	36.9	GO:0043025	neuronal cell body(GO:0043025)
0.3	0.8	GO:0030061	mitochondrial crista(GO:0030061)
0.3	1.8	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2	1.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2	1.7	GO:0070187	telosome(GO:0070187)
0.2	1.9	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.2	26.4	GO:0043209	myelin sheath(GO:0043209)
0.2	0.2	GO:0001520	outer dense fiber(GO:0001520)
0.2	3.8	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2	0.2	GO:0090543	Flemming body(GO:0090543)
0.2	2.3	GO:0099503	secretory vesicle(GO:0099503)
0.2	0.9	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.2	0.7	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.2	0.4	GO:0032585	multivesicular body membrane(GO:0032585)
0.2	0.8	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	4.6	GO:0030315	T-tubule(GO:0030315)
0.2	1.0	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2	172.3	GO:0005794	Golgi apparatus(GO:0005794)
0.2	0.8	GO:0032009	early phagosome(GO:0032009)
0.2	2.1	GO:0005652	nuclear lamina(GO:0005652)
0.2	0.6	GO:0005588	collagen type V trimer(GO:0005588)
0.2	0.9	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.2	2.2	GO:0030659	cytoplasmic vesicle membrane(GO:0030659)
0.2	1.3	GO:0016272	prefoldin complex(GO:0016272)
0.2	0.9	GO:0001650	fibrillar center(GO:0001650)
0.2	7.1	GO:0045095	keratin filament(GO:0045095)
0.2	2.3	GO:0000800	lateral element(GO:0000800)
0.2	2.5	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	1.0	GO:0042587	glycogen granule(GO:0042587)
0.2	0.3	GO:0030427	site of polarized growth(GO:0030427)
0.2	0.5	GO:0030175	filopodium(GO:0030175)
0.2	0.2	GO:0012506	vesicle membrane(GO:0012506)
0.1	0.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	1.3	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	0.3	GO:0034464	BBSome(GO:0034464)
0.1	4.7	GO:0030863	cortical cytoskeleton(GO:0030863)
0.1	0.7	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1	1.8	GO:0044297	cell body(GO:0044297)
0.1	0.3	GO:0005775	vacuolar lumen(GO:0005775)
0.1	107.3	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.1	9.1	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	4.0	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.1	1.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.9	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	1.6	GO:0000974	Prp19 complex(GO:0000974)
0.1	0.5	GO:0098536	deuterosome(GO:0098536)
0.1	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	0.5	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	0.6	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	7.3	GO:0097458	neuron part(GO:0097458)
0.1	0.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	59.9	GO:0005886	plasma membrane(GO:0005886)
0.1	1.4	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	24.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.1	44.6	GO:0030054	cell junction(GO:0030054)
0.1	2.9	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1	0.1	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	2.5	GO:0000502	proteasome complex(GO:0000502)
0.1	0.5	GO:0000812	Swr1 complex(GO:0000812)
0.1	0.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	0.4	GO:0038201	TOR complex(GO:0038201)
0.1	0.9	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	0.2	GO:0043511	inhibin complex(GO:0043511)
0.1	1.4	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	1.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	21.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.1	GO:0071547	piP-body(GO:0071547)
0.1	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.1	GO:0005594	FACIT collagen trimer(GO:0005593) collagen type IX trimer(GO:0005594)
0.1	1.0	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	265.7	GO:0016021	integral component of membrane(GO:0016021)
0.1	0.5	GO:0030904	retromer complex(GO:0030904)
0.1	4.0	GO:0072372	primary cilium(GO:0072372)
0.1	3.0	GO:0016324	apical plasma membrane(GO:0016324)
0.1	0.7	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.1	0.8	GO:0097346	Ino80 complex(GO:0031011) INO80-type complex(GO:0097346)
0.1	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	7.8	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.1	159.4	GO:0005576	extracellular region(GO:0005576)
0.1	0.1	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.2	GO:0098862	cluster of actin-based cell projections(GO:0098862)
0.1	0.7	GO:0042555	MCM complex(GO:0042555)
0.1	0.7	GO:0032982	myosin filament(GO:0032982)
0.1	0.7	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	1.7	GO:0032040	small-subunit processome(GO:0032040)
0.1	0.3	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.1	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	212.2	GO:0005634	nucleus(GO:0005634)
0.1	0.2	GO:0097225	sperm midpiece(GO:0097225)
0.1	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	1.2	GO:0005769	early endosome(GO:0005769)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	0.5	GO:0005758	mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0	0.5	GO:0005871	kinesin complex(GO:0005871)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	15.4	GO:0016020	membrane(GO:0016020)
0.0	0.2	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0030139	endocytic vesicle(GO:0030139)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0098798	mitochondrial protein complex(GO:0098798)
0.0	0.2	GO:0030018	Z disc(GO:0030018)
0.0	0.3	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	1.3	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)
0.0	0.0	GO:0030027	lamellipodium(GO:0030027)
0.0	0.3	GO:0005768	endosome(GO:0005768)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0031988	membrane-bounded vesicle(GO:0031988)
0.0	0.2	GO:0009986	cell surface(GO:0009986)
0.0	0.3	GO:0005694	chromosome(GO:0005694)
0.0	0.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.0	GO:0031417	NatC complex(GO:0031417)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
19.1	114.9	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
17.0	51.1	GO:0097109	neuroligin family protein binding(GO:0097109)
11.8	59.2	GO:0004985	opioid receptor activity(GO:0004985)
11.0	33.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
11.0	44.0	GO:0030911	TPR domain binding(GO:0030911)
10.2	30.5	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
9.2	46.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
8.5	42.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
8.3	24.8	GO:0004351	glutamate decarboxylase activity(GO:0004351)
7.9	63.5	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
7.9	31.4	GO:0015375	glycine:sodium symporter activity(GO:0015375)
7.5	45.1	GO:0005499	vitamin D binding(GO:0005499)
7.0	56.4	GO:0008430	selenium binding(GO:0008430)
6.7	33.6	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
6.7	26.7	GO:0004969	histamine receptor activity(GO:0004969)
6.3	126.8	GO:0017075	syntaxin-1 binding(GO:0017075)
5.4	21.8	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
5.4	27.0	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
5.4	16.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
5.0	19.8	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
4.8	57.1	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
4.7	23.4	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
4.5	27.1	GO:0016595	glutamate binding(GO:0016595)
4.4	83.0	GO:0004890	GABA-A receptor activity(GO:0004890)
4.4	47.9	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
4.3	21.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
4.0	52.0	GO:0015279	store-operated calcium channel activity(GO:0015279)
3.9	85.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
3.7	51.8	GO:0046625	sphingolipid binding(GO:0046625)
3.6	47.1	GO:0015643	toxic substance binding(GO:0015643)
3.3	94.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
3.2	45.0	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
3.2	48.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
3.2	38.1	GO:0031005	filamin binding(GO:0031005)
3.0	9.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
3.0	44.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
2.6	23.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
2.2	12.9	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
2.0	22.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
2.0	53.8	GO:0001786	phosphatidylserine binding(GO:0001786)
2.0	13.7	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
1.9	5.8	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
1.9	34.9	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.7	47.0	GO:0030507	spectrin binding(GO:0030507)
1.7	5.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
1.6	13.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
1.5	19.8	GO:0008253	5'-nucleotidase activity(GO:0008253)
1.5	48.3	GO:0004364	glutathione transferase activity(GO:0004364)
1.5	4.5	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
1.4	11.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.4	11.3	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
1.3	13.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
1.3	19.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
1.2	11.0	GO:0042043	neurexin family protein binding(GO:0042043)
1.2	8.5	GO:0005000	vasopressin receptor activity(GO:0005000)
1.1	31.5	GO:0045296	cadherin binding(GO:0045296)
1.1	33.7	GO:0015485	cholesterol binding(GO:0015485)
1.0	3.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
1.0	27.9	GO:0001540	beta-amyloid binding(GO:0001540)
1.0	30.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
1.0	4.8	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.9	39.5	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.9	21.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.9	3.6	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.9	13.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.8	1.7	GO:0030284	estrogen receptor activity(GO:0030284)
0.8	9.8	GO:0070182	DNA polymerase binding(GO:0070182)
0.8	73.4	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.8	23.4	GO:0005267	potassium channel activity(GO:0005267)
0.8	19.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.8	3.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.7	188.5	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.7	78.8	GO:0002020	protease binding(GO:0002020)
0.7	2.8	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.7	2.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.7	1.4	GO:0002046	opsin binding(GO:0002046)
0.7	2.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.7	2.0	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.6	2.5	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.6	1.9	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.6	104.1	GO:0003729	mRNA binding(GO:0003729)
0.6	1.8	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.6	0.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.6	2.4	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.6	1.8	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.6	49.3	GO:0000149	SNARE binding(GO:0000149)
0.6	48.6	GO:0005179	hormone activity(GO:0005179)
0.6	6.1	GO:0097602	cullin family protein binding(GO:0097602)
0.5	3.6	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.5	2.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.5	26.1	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.5	2.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.5	11.1	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.5	1.4	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.5	16.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.5	7.9	GO:0005246	calcium channel regulator activity(GO:0005246)
0.5	1.8	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.4	12.9	GO:0035254	glutamate receptor binding(GO:0035254)
0.4	0.8	GO:0003680	AT DNA binding(GO:0003680)
0.4	5.5	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.4	0.8	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4	2.5	GO:0048495	Roundabout binding(GO:0048495)
0.4	1.6	GO:0005047	signal recognition particle binding(GO:0005047)
0.4	1.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4	1.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4	1.6	GO:0009374	biotin binding(GO:0009374)
0.4	34.0	GO:0005261	cation channel activity(GO:0005261)
0.4	4.6	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.4	5.3	GO:0070888	E-box binding(GO:0070888)
0.4	1.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.4	7.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.4	1.4	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.3	3.8	GO:0030506	ankyrin binding(GO:0030506)
0.3	1.4	GO:0050542	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.3	8.9	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.3	7.2	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.3	2.0	GO:0005113	patched binding(GO:0005113)
0.3	1.0	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3	1.0	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.3	1.3	GO:0033691	sialic acid binding(GO:0033691)
0.3	1.6	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.3	10.2	GO:0051018	protein kinase A binding(GO:0051018)
0.3	1.9	GO:0042165	neurotransmitter binding(GO:0042165)
0.3	0.6	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.3	3.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.3	17.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.3	2.4	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.3	1.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.3	0.9	GO:0070051	fibrinogen binding(GO:0070051)
0.3	1.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.3	1.8	GO:0008517	folic acid transporter activity(GO:0008517)
0.3	1.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.3	1.4	GO:0004565	beta-galactosidase activity(GO:0004565)
0.3	1.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.3	0.9	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.3	0.8	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	1.8	GO:0070513	death domain binding(GO:0070513)
0.3	2.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.3	6.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.3	0.8	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.3	0.8	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.3	113.4	GO:0005509	calcium ion binding(GO:0005509)
0.2	2.7	GO:0070628	proteasome binding(GO:0070628)
0.2	0.5	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2	0.7	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.2	0.7	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.2	3.9	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.2	0.2	GO:0004096	catalase activity(GO:0004096)
0.2	2.9	GO:0036002	pre-mRNA binding(GO:0036002)
0.2	2.9	GO:0005343	organic acid:sodium symporter activity(GO:0005343)
0.2	0.4	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.2	5.6	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.2	2.5	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.2	0.6	GO:0042609	CD4 receptor binding(GO:0042609)
0.2	1.6	GO:0039706	co-receptor binding(GO:0039706)
0.2	0.4	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.2	3.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	1.0	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2	4.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.2	0.2	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.2	0.4	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.2	2.7	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.2	0.4	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	0.9	GO:0031849	olfactory receptor binding(GO:0031849)
0.2	0.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.2	0.2	GO:0042605	peptide antigen binding(GO:0042605)
0.2	1.7	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	0.3	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.2	5.1	GO:0043883	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.2	1.0	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.2	0.2	GO:0045182	translation regulator activity(GO:0045182)
0.2	0.3	GO:0071532	ankyrin repeat binding(GO:0071532)
0.2	2.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.2	0.8	GO:0032027	myosin light chain binding(GO:0032027)
0.2	4.3	GO:0005109	frizzled binding(GO:0005109)
0.2	1.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2	12.5	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.2	0.9	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	7.1	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.1	2.0	GO:0008242	omega peptidase activity(GO:0008242)
0.1	0.8	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.5	GO:0052859	dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1	1.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.5	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	0.1	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.4	GO:0004966	galanin receptor activity(GO:0004966)
0.1	0.6	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.8	GO:0001163	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1	0.4	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.1	0.3	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.1	0.2	GO:0051373	FATZ binding(GO:0051373)
0.1	2.6	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	3.1	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	24.4	GO:0015631	tubulin binding(GO:0015631)
0.1	4.2	GO:0003924	GTPase activity(GO:0003924)
0.1	2.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	16.9	GO:0000287	magnesium ion binding(GO:0000287)
0.1	0.4	GO:0038100	nodal binding(GO:0038100)
0.1	0.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	1.0	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1	2.1	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	4.9	GO:0046332	SMAD binding(GO:0046332)
0.1	1.4	GO:0010181	FMN binding(GO:0010181)
0.1	0.8	GO:0046961	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.3	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	3.8	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1	3.0	GO:0050661	NADP binding(GO:0050661)
0.1	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.1	2.4	GO:0019843	rRNA binding(GO:0019843)
0.1	0.4	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.1	3.6	GO:0000049	tRNA binding(GO:0000049)
0.1	0.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.6	GO:0052630	RNA guanylyltransferase activity(GO:0008192) tRNA guanylyltransferase activity(GO:0008193) CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.1	0.9	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	0.7	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	2.3	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	0.4	GO:0015321	sodium:phosphate symporter activity(GO:0005436) sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.1	0.6	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.7	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
0.1	0.5	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.4	GO:0004337	geranyltranstransferase activity(GO:0004337)
0.1	0.4	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.4	GO:0033265	choline binding(GO:0033265)
0.1	5.1	GO:0030674	protein binding, bridging(GO:0030674)
0.1	9.8	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1	0.3	GO:1990254	keratin filament binding(GO:1990254)
0.1	2.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.6	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	5.6	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.1	GO:0034618	arginine binding(GO:0034618)
0.1	0.2	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.1	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	0.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.7	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.1	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.3	GO:0008933	lytic transglycosylase activity(GO:0008933)
0.1	0.5	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	0.7	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.1	2.7	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.1	0.3	GO:0008494	translation activator activity(GO:0008494)
0.1	0.9	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.4	GO:0036310	annealing helicase activity(GO:0036310)
0.1	0.9	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.6	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.1	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	2.7	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1	2.2	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1	0.5	GO:0035173	histone kinase activity(GO:0035173)
0.1	25.1	GO:0005198	structural molecule activity(GO:0005198)
0.1	4.9	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	0.3	GO:0035473	lipase binding(GO:0035473)
0.1	2.4	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.1	0.2	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.5	GO:0050681	androgen receptor binding(GO:0050681)
0.1	0.9	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.6	GO:0036218	thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.1	0.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.9	GO:0001968	fibronectin binding(GO:0001968)
0.1	3.9	GO:0030792	methylarsonite methyltransferase activity(GO:0030792)
0.1	0.4	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	0.4	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.2	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.1	12.7	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1	1.7	GO:0016831	carboxy-lyase activity(GO:0016831)
0.1	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	0.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	0.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	6.2	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.1	2.0	GO:0004386	helicase activity(GO:0004386)
0.1	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.5	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.1	0.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.3	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1	0.4	GO:0015459	potassium channel regulator activity(GO:0015459)
0.1	0.2	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.2	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.2	GO:0048030	disaccharide binding(GO:0048030)
0.1	0.2	GO:0048156	tau protein binding(GO:0048156)
0.0	1.4	GO:0010296	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.5	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	0.7	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	1.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.2	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.9	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.0	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.4	GO:0034841	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.5	GO:0043748	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0	0.2	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.8	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	2.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.5	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	1.2	GO:0005507	copper ion binding(GO:0005507)
0.0	0.1	GO:0003823	antigen binding(GO:0003823)
0.0	0.6	GO:0000907	sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0	0.0	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.6	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0052744	phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0	0.3	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.3	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.6	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.7	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	2.1	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.4	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.3	GO:0022832	voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	2.0	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.4	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	4.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	2.4	GO:0008565	protein transporter activity(GO:0008565)
0.0	3.3	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.3	GO:0034871	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	1.7	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.1	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0	0.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.8	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.3	GO:0019956	chemokine binding(GO:0019956)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.9	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0016247	channel regulator activity(GO:0016247)
0.0	0.0	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	22.7	GO:0003723	RNA binding(GO:0003723)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	94.5	GO:0005515	protein binding(GO:0005515)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.6	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0043176	amine binding(GO:0043176)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.6	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.2	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.1	GO:0008483	transaminase activity(GO:0008483)
0.0	0.0	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.0	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	1.0	GO:0030414	peptidase inhibitor activity(GO:0030414)
0.0	0.2	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0	0.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.0	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	57.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.9	10.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.6	15.8	PID REELIN PATHWAY	Reelin signaling pathway
0.6	34.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.6	10.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.5	19.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.5	15.7	ST G ALPHA I PATHWAY	G alpha i Pathway
0.4	9.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	66.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.4	5.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.4	9.5	PID RAS PATHWAY	Regulation of Ras family activation
0.4	36.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.4	4.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.3	12.0	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.3	0.9	PID TRAIL PATHWAY	TRAIL signaling pathway
0.3	75.2	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.3	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.3	3.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.2	2.9	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	3.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.2	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2	0.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	2.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	1.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	4.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	2.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.0	PID BARD1 PATHWAY	BARD1 signaling events
0.1	2.7	PID BMP PATHWAY	BMP receptor signaling
0.1	1.5	PID ARF 3PATHWAY	Arf1 pathway
0.1	1.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	1.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	1.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	0.4	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	1.8	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	1.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	1.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	1.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	1.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	1.6	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	2.1	PID AURORA B PATHWAY	Aurora B signaling
0.1	1.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	1.7	PID NOTCH PATHWAY	Notch signaling pathway
0.1	7.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	0.8	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.0	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.2	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	6.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.8	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.6	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID E2F PATHWAY	E2F transcription factor network
0.0	0.2	PID ATR PATHWAY	ATR signaling pathway
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.5	189.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
8.4	92.8	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
6.5	52.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
4.4	48.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
4.1	45.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
3.7	55.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
3.7	51.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
3.3	46.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
3.2	67.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
2.9	20.0	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.7	37.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
2.5	59.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
2.5	19.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
2.4	33.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
2.3	43.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
2.2	22.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
2.2	59.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
2.1	6.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
1.9	78.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
1.7	33.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
1.5	17.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.4	17.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.4	57.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.8	19.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.8	3.0	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.7	11.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.7	28.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.7	16.6	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.7	7.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.6	6.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.5	14.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.5	8.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.5	69.5	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.5	23.3	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.4	4.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.4	0.4	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.4	10.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.3	1.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	19.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	3.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	18.7	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.3	11.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	2.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	3.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2	3.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	1.9	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	0.4	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.2	2.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	2.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.2	0.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	1.1	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.2	6.0	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.2	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.2	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.2	2.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	1.5	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	1.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	2.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.6	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	1.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	21.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	1.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.9	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1	0.7	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	0.9	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	5.2	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	2.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	0.8	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	1.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	1.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	0.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	0.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	1.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.9	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.8	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	2.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	0.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.8	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	0.6	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	0.1	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.1	0.3	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.1	0.9	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	0.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	1.6	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	4.7	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.4	REACTOME PLATELET HOMEOSTASIS	Genes involved in Platelet homeostasis
0.0	1.2	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.3	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.7	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.7	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	1.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	1.0	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME XENOBIOTICS	Genes involved in Xenobiotics

Results for Rest

Z-value: 8.44

Motif logo

Transcription factors associated with Rest

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Rest motif across conditions

Conditions sorted by the z-value of the Rest motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rest

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: