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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Smad2

Z-value: 1.08

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Transcription factors associated with Smad2

Gene Symbol	Gene ID	Gene Info
Smad2 Ensembl NCBI MGI UniProt	ENSMUSG00000024563.9	SMAD family member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr18_76246001_76246152	Smad2	3902	0.215680	0.44	4.3e-04	Click!
chr18_76259555_76259706	Smad2	1491	0.409246	-0.21	1.1e-01	Click!
chr18_76239394_76239545	Smad2	2111	0.290612	0.17	1.8e-01	Click!
chr18_76243576_76243953	Smad2	1590	0.367135	-0.13	3.1e-01	Click!
chr18_76254565_76254716	Smad2	6481	0.196857	-0.13	3.3e-01	Click!

Activity of the Smad2 motif across conditions

Conditions sorted by the z-value of the Smad2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_80300884_80302968	5.92	Apc2	APC regulator of WNT signaling pathway 2	106	0.9
chr11_87759834_87761999	2.91	Tspoap1	TSPO associated protein 1	329	0.75
chr11_55607331_55608633	2.66	Glra1	glycine receptor, alpha 1 subunit	161	0.96
chr13_105249326_105250833	2.64	Rnf180	ring finger protein 180	20960	0.22
chr10_87491430_87491970	2.60	Ascl1	achaete-scute family bHLH transcription factor 1	1960	0.34
chr3_17792584_17792950	2.60	Mir124-2hg	Mir124-2 host gene (non-protein coding)	1153	0.46
chr2_158610228_158611991	2.53	Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	342	0.44
chr1_158364281_158364968	2.46	Astn1	astrotactin 1	2074	0.31
chr6_124989874_124990298	2.23	Pianp	PILR alpha associated neural protein	6608	0.08
chr1_42700819_42701404	2.13	Pou3f3	POU domain, class 3, transcription factor 3	5343	0.14
chr15_78717021_78717410	2.10	Elfn2	leucine rich repeat and fibronectin type III, extracellular 2	898	0.51
chr5_124184090_124186568	2.05	Pitpnm2	phosphatidylinositol transfer protein, membrane-associated 2	211	0.9
chr4_126465012_126466992	2.04	Ago1	argonaute RISC catalytic subunit 1	2419	0.18
chr5_120433178_120434996	2.04	Gm27199	predicted gene 27199	2320	0.19
chr7_44336079_44337576	1.92	Shank1	SH3 and multiple ankyrin repeat domains 1	811	0.34
chr7_25004827_25006284	1.92	Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	340	0.79
chr6_90781027_90782541	1.90	Iqsec1	IQ motif and Sec7 domain 1	188	0.94
chr5_115431565_115432258	1.84	Msi1	musashi RNA-binding protein 1	1306	0.22
chr15_76519928_76521866	1.77	Scrt1	scratch family zinc finger 1	1005	0.28
chr9_112234066_112234966	1.77	Arpp21	cyclic AMP-regulated phosphoprotein, 21	93	0.56
chr1_115684558_115685809	1.75	Cntnap5a	contactin associated protein-like 5A	427	0.58
chr3_152979582_152980188	1.72	St6galnac5	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	2167	0.29
chr7_44443183_44443767	1.70	Lrrc4b	leucine rich repeat containing 4B	738	0.4
chrX_110817183_110817473	1.68	Pou3f4	POU domain, class 3, transcription factor 4	3048	0.3
chr8_123409926_123410387	1.68	Tubb3	tubulin, beta 3 class III	1268	0.19
chr1_167003423_167003635	1.61	Fam78b	family with sequence similarity 78, member B	1940	0.31
chr8_12399326_12400483	1.59	Gm25239	predicted gene, 25239	3501	0.16
chr2_70561988_70564432	1.58	Gad1os	glutamate decarboxylase 1, opposite strand	147	0.61
chr4_148286849_148288201	1.58	Disp3	dispatched RND transporter family member 3	440	0.81
chr14_32461435_32461940	1.56	Chat	choline acetyltransferase	355	0.82
chr1_132739015_132739278	1.55	Nfasc	neurofascin	2611	0.28
chr3_17790150_17790808	1.53	Mir124-2hg	Mir124-2 host gene (non-protein coding)	522	0.77
chr17_93198991_93201483	1.53	Adcyap1	adenylate cyclase activating polypeptide 1	302	0.89
chr7_139833633_139836105	1.52	Adgra1	adhesion G protein-coupled receptor A1	93	0.96
chr4_42950234_42951162	1.51	Dnajb5	DnaJ heat shock protein family (Hsp40) member B5	258	0.87
chr1_79450112_79451070	1.49	Scg2	secretogranin II	10471	0.24
chr1_157243489_157244692	1.47	Rasal2	RAS protein activator like 2	400	0.88
chr19_47019038_47019748	1.46	Nt5c2	5'-nucleotidase, cytosolic II	4240	0.14
chr3_88206822_88208169	1.44	Gm3764	predicted gene 3764	183	0.86
chr1_172056022_172057415	1.44	Nhlh1	nescient helix loop helix 1	855	0.45
chr14_66344363_66345813	1.40	Stmn4	stathmin-like 4	707	0.65
chr7_45870455_45871042	1.39	Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	319	0.72
chr1_173366699_173367980	1.39	Cadm3	cell adhesion molecule 3	294	0.89
chr11_76466993_76468433	1.38	Abr	active BCR-related gene	585	0.77
chr8_108535196_108536010	1.37	Gm39244	predicted gene, 39244	1344	0.54
chr16_18628119_18628292	1.36	Septin5	septin 5	1499	0.25
chr7_133759283_133760291	1.33	Dhx32	DEAH (Asp-Glu-Ala-His) box polypeptide 32	42	0.96
chr14_64592253_64592626	1.27	Mir3078	microRNA 3078	1254	0.34
chr16_9994378_9995594	1.27	Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	63	0.98
chr1_42711455_42712692	1.24	Pantr2	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2	1381	0.34
chr7_51617528_51617727	1.24	Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	4379	0.23
chr15_83738954_83739105	1.23	Scube1	signal peptide, CUB domain, EGF-like 1	14008	0.21
chr13_8208750_8209243	1.21	Adarb2	adenosine deaminase, RNA-specific, B2	6074	0.19
chr2_20964477_20964628	1.20	Arhgap21	Rho GTPase activating protein 21	3168	0.24
chr8_89038877_89039267	1.20	Sall1	spalt like transcription factor 1	5090	0.25
chr9_90828615_90829226	1.20	Gm28703	predicted gene 28703	60	0.98
chr4_110285468_110287125	1.19	Elavl4	ELAV like RNA binding protein 4	320	0.94
chr9_91361494_91362853	1.17	Zic4	zinc finger protein of the cerebellum 4	240	0.8
chr19_46505781_46506898	1.15	Trim8	tripartite motif-containing 8	4637	0.17
chr6_112943851_112944495	1.15	Srgap3	SLIT-ROBO Rho GTPase activating protein 3	2581	0.19
chr14_61044716_61045217	1.14	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	1503	0.43
chr9_107401822_107402928	1.14	Cacna2d2	calcium channel, voltage-dependent, alpha 2/delta subunit 2	2306	0.19
chr5_113492294_113493538	1.14	Wscd2	WSC domain containing 2	2164	0.36
chr8_69183133_69184264	1.14	Lzts1	leucine zipper, putative tumor suppressor 1	507	0.76
chr10_29143400_29144848	1.13	Soga3	SOGA family member 3	65	0.5
chr1_146494200_146495557	1.13	Gm29514	predicted gene 29514	73	0.56
chr17_48933923_48934074	1.12	Lrfn2	leucine rich repeat and fibronectin type III domain containing 2	1619	0.51
chr15_85576096_85578271	1.12	Wnt7b	wingless-type MMTV integration site family, member 7B	887	0.54
chr3_84952327_84953098	1.12	Fbxw7	F-box and WD-40 domain protein 7	566	0.84
chrX_140278669_140278820	1.12	Gm15046	predicted gene 15046	882	0.64
chr16_42338101_42338699	1.12	Gap43	growth associated protein 43	2251	0.38
chr7_51631759_51631973	1.11	Gm45072	predicted gene 45072	141	0.96
chr10_90576163_90577493	1.11	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B	13	0.99
chr2_105678552_105679922	1.11	Pax6	paired box 6	630	0.68
chr19_19108280_19109261	1.10	Rorb	RAR-related orphan receptor beta	2426	0.42
chr10_127533543_127535232	1.10	Nxph4	neurexophilin 4	172	0.9
chr5_139546076_139547826	1.09	Uncx	UNC homeobox	3053	0.23
chr19_47015573_47015946	1.08	Nt5c2	5'-nucleotidase, cytosolic II	606	0.53
chr9_58197310_58202560	1.08	Islr2	immunoglobulin superfamily containing leucine-rich repeat 2	637	0.54
chr2_13007832_13008609	1.08	Gm37811	predicted gene, 37811	1666	0.25
chr4_122997127_122997278	1.07	Mycl	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived	1103	0.42
chr16_7052477_7052791	1.07	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	17212	0.31
chr1_77503797_77505059	1.07	Mir6352	microRNA 6352	7660	0.19
chr5_142509074_142510203	1.07	Radil	Ras association and DIL domains	21	0.97
chr11_6604031_6604533	1.07	Nacad	NAC alpha domain containing	1771	0.17
chr13_59144151_59144397	1.06	Gm34307	predicted gene, 34307	1554	0.28
chr8_112570000_112570856	1.04	Cntnap4	contactin associated protein-like 4	373	0.76
chr3_17791321_17791472	1.04	Mir124-2hg	Mir124-2 host gene (non-protein coding)	1439	0.39
chr11_98327227_98329144	1.04	Neurod2	neurogenic differentiation 2	1463	0.23
chr10_80145023_80147388	1.04	Midn	midnolin	2067	0.14
chr4_22491084_22492166	1.02	Gm30731	predicted gene, 30731	1077	0.46
chr5_107498136_107498752	1.02	Btbd8	BTB (POZ) domain containing 8	665	0.57
chr16_88289433_88290388	1.02	Grik1	glutamate receptor, ionotropic, kainate 1	46	0.98
chr2_181714758_181715334	1.01	Oprl1	opioid receptor-like 1	0	0.96
chr8_4216103_4217573	1.01	Prr36	proline rich 36	74	0.93
chr11_33146801_33147370	1.00	Fgf18	fibroblast growth factor 18	290	0.88
chr13_49319308_49320561	1.00	Fgd3	FYVE, RhoGEF and PH domain containing 3	377	0.86
chr15_25761251_25761829	0.99	Myo10	myosin X	2755	0.32
chr4_68951885_68952234	0.98	Brinp1	bone morphogenic protein/retinoic acid inducible neural specific 1	2338	0.46
chr8_94997776_94998724	0.98	Adgrg1	adhesion G protein-coupled receptor G1	2589	0.18
chr8_34890130_34891317	0.98	Tnks	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	572	0.8
chr7_78887986_78888346	0.97	Mir7-2	microRNA 7-2	111	0.94
chr9_107403223_107403374	0.97	Cacna2d2	calcium channel, voltage-dependent, alpha 2/delta subunit 2	3229	0.15
chr10_117675574_117676482	0.96	Cpm	carboxypeptidase M	135	0.94
chr2_74720066_74720639	0.96	Hoxd4	homeobox D4	1626	0.13
chr5_103209022_103210413	0.96	Mapk10	mitogen-activated protein kinase 10	705	0.75
chr4_141534067_141534218	0.93	Spen	spen family transcription repressor	4111	0.16
chrX_6778939_6780421	0.93	Dgkk	diacylglycerol kinase kappa	374	0.92
chr2_181769553_181769907	0.93	Myt1	myelin transcription factor 1	2218	0.24
chr7_4842332_4842483	0.92	Shisa7	shisa family member 7	2289	0.13
chr6_124998125_124999247	0.91	Pianp	PILR alpha associated neural protein	47	0.94
chrX_101301762_101302890	0.91	Nlgn3	neuroligin 3	1852	0.2
chrX_48523279_48523924	0.91	Rab33a	RAB33A, member RAS oncogene family	4316	0.19
chrX_72655248_72656218	0.90	Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3	453	0.82
chr7_34753113_34753812	0.90	Chst8	carbohydrate sulfotransferase 8	350	0.89
chr7_127761471_127761622	0.90	Orai3	ORAI calcium release-activated calcium modulator 3	8269	0.07
chr3_89522754_89523224	0.90	Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	2825	0.22
chr2_152080491_152081480	0.88	Scrt2	scratch family zinc finger 2	544	0.7
chr2_14740186_14740953	0.88	Gm10848	predicted gene 10848	847	0.36
chr1_187998988_187999336	0.88	Esrrg	estrogen-related receptor gamma	1294	0.52
chr8_8650243_8650938	0.87	Gm45073	predicted gene 45073	3578	0.12
chr3_88200201_88201358	0.87	AW047730	expressed sequence AW047730	144	0.89
chr9_97016638_97017172	0.87	Gm16010	predicted gene 16010	569	0.65
chr12_70107861_70108470	0.87	Nin	ninein	3406	0.2
chr2_158606690_158608449	0.86	Gm14204	predicted gene 14204	3021	0.15
chr18_43058416_43059778	0.86	Ppp2r2b	protein phosphatase 2, regulatory subunit B, beta	374	0.86
chr7_79502506_79503035	0.86	Mir9-3	microRNA 9-3	2494	0.13
chr7_62422629_62423664	0.86	Gm32061	predicted gene, 32061	99	0.96
chrX_9202282_9203095	0.85	Lancl3	LanC lantibiotic synthetase component C-like 3 (bacterial)	2786	0.21
chr4_148284201_148285628	0.85	Disp3	dispatched RND transporter family member 3	3051	0.22
chr2_181715341_181715994	0.85	Oprl1	opioid receptor-like 1	35	0.95
chrX_161719845_161720465	0.85	Rai2	retinoic acid induced 2	2528	0.41
chr2_52557337_52558561	0.85	Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	611	0.74
chr8_47285815_47285966	0.84	Stox2	storkhead box 2	3472	0.3
chr3_127498048_127498199	0.84	Ank2	ankyrin 2, brain	878	0.38
chr8_9768980_9769453	0.84	Fam155a	family with sequence similarity 155, member A	888	0.47
chr4_140646568_140646801	0.84	Arhgef10l	Rho guanine nucleotide exchange factor (GEF) 10-like	2066	0.27
chr2_178327060_178328225	0.84	Phactr3	phosphatase and actin regulator 3	86	0.98
chr2_35662845_35663372	0.84	Dab2ip	disabled 2 interacting protein	1489	0.47
chrX_93289773_93291216	0.83	Arx	aristaless related homeobox	3984	0.28
chrX_169827012_169827288	0.82	Mid1	midline 1	1009	0.63
chr14_25610327_25611867	0.82	Zmiz1	zinc finger, MIZ-type containing 1	3259	0.25
chr5_108549212_108550612	0.81	Cplx1	complexin 1	88	0.95
chr12_14149643_14150928	0.81	Lratd1	LRAT domain containing 1	1064	0.58
chr14_93888463_93888979	0.81	Pcdh9	protocadherin 9	11	0.99
chr5_27264978_27265420	0.81	Dpp6	dipeptidylpeptidase 6	3224	0.31
chr1_172015756_172015958	0.81	Vangl2	VANGL planar cell polarity 2	6828	0.14
chr14_124191809_124193012	0.80	Fgf14	fibroblast growth factor 14	492	0.88
chrX_7919510_7921219	0.80	Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor	542	0.52
chr6_55678280_55679200	0.80	Neurod6	neurogenic differentiation 6	2523	0.32
chr13_83736071_83736534	0.80	Gm33366	predicted gene, 33366	2233	0.18
chr19_38266301_38266452	0.80	Lgi1	leucine-rich repeat LGI family, member 1	966	0.51
chr13_44946654_44947258	0.79	Dtnbp1	dystrobrevin binding protein 1	188	0.96
chrX_169829262_169829609	0.79	Mid1	midline 1	1276	0.55
chrX_23284413_23285126	0.79	Klhl13	kelch-like 13	60	0.99
chr11_102394791_102396113	0.79	Rundc3a	RUN domain containing 3A	2049	0.17
chr1_60564320_60564471	0.79	Raph1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	2370	0.22
chr1_66321652_66322390	0.79	Map2	microtubule-associated protein 2	23	0.98
chr5_116589538_116590511	0.78	Srrm4	serine/arginine repetitive matrix 4	1793	0.34
chr9_69758963_69761490	0.78	Foxb1	forkhead box B1	714	0.5
chr8_122018594_122018745	0.78	Banp	BTG3 associated nuclear protein	17822	0.14
chr14_66346338_66346694	0.78	Stmn4	stathmin-like 4	2135	0.28
chr11_104234777_104235157	0.78	Mapt	microtubule-associated protein tau	3383	0.19
chr2_181763361_181764530	0.78	Myt1	myelin transcription factor 1	613	0.66
chr2_94239500_94239893	0.78	Mir129b	microRNA 129b	1682	0.24
chr5_37248332_37249378	0.77	Crmp1	collapsin response mediator protein 1	1570	0.39
chr2_90887202_90887559	0.77	C1qtnf4	C1q and tumor necrosis factor related protein 4	1520	0.23
chr2_24905345_24905684	0.77	Gm37139	predicted gene, 37139	11648	0.09
chr15_103167699_103167910	0.77	Smug1	single-strand selective monofunctional uracil DNA glycosylase	712	0.54
chr2_74725879_74728683	0.77	Hoxd4	homeobox D4	207	0.67
chr6_119328752_119331284	0.77	Lrtm2	leucine-rich repeats and transmembrane domains 2	739	0.43
chr2_30995683_30996883	0.76	Usp20	ubiquitin specific peptidase 20	235	0.9
chr11_57011668_57012922	0.76	Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	339	0.94
chr19_10342320_10342596	0.76	Dagla	diacylglycerol lipase, alpha	37581	0.11
chr3_153974193_153974458	0.75	Slc44a5	solute carrier family 44, member 5	889	0.51
chr1_143643096_143643376	0.75	Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component	711	0.65
chr1_133048968_133049307	0.75	Pik3c2b	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta	3125	0.19
chr7_29314313_29315903	0.75	Dpf1	D4, zinc and double PHD fingers family 1	45	0.96
chr8_70083658_70084944	0.74	Hapln4	hyaluronan and proteoglycan link protein 4	157	0.9
chr1_9649287_9649464	0.74	Gm29520	predicted gene 29520	8793	0.14
chr8_122676055_122676213	0.74	Cbfa2t3	CBFA2/RUNX1 translocation partner 3	1938	0.19
chr1_172484027_172485046	0.74	Igsf9	immunoglobulin superfamily, member 9	2222	0.17
chr8_12503619_12503770	0.74	4933439N14Rik	RIKEN cDNA 4933439N14 gene	795	0.62
chr10_49787984_49789251	0.74	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	137	0.6
chr2_146745280_146745983	0.74	Gm14111	predicted gene 14111	10074	0.27
chr2_14739165_14739970	0.73	Gm10848	predicted gene 10848	155	0.7
chr15_25753741_25754105	0.73	Myo10	myosin X	944	0.64
chr4_153476839_153476990	0.73	Ajap1	adherens junction associated protein 1	5265	0.34
chr13_107887317_107887562	0.72	Zswim6	zinc finger SWIM-type containing 6	2625	0.35
chr7_79498955_79500626	0.72	Mir9-3hg	Mir9-3 host gene	236	0.84
chr7_25003930_25004291	0.71	Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	1785	0.21
chr7_44441951_44442938	0.71	Lrrc4b	leucine rich repeat containing 4B	41	0.93
chr17_43952337_43954220	0.71	Rcan2	regulator of calcineurin 2	27	0.99
chr5_114569026_114570120	0.71	Fam222a	family with sequence similarity 222, member A	1556	0.35
chr1_24869771_24870242	0.71	Gm28594	predicted gene 28594	41653	0.16
chr4_124893834_124895373	0.70	1700125G02Rik	RIKEN cDNA 1700125G02 gene	179	0.9
chr14_55112041_55112310	0.70	Jph4	junctophilin 4	1617	0.2
chrY_90826579_90826784	0.70	Gm21742	predicted gene, 21742	10732	0.18
chr16_77420100_77420782	0.70	9430053O09Rik	RIKEN cDNA 9430053O09 gene	1379	0.28
chr5_26904124_26905425	0.70	Dpp6	dipeptidylpeptidase 6	79	0.98

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Smad2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.6	1.2	GO:0048880	sensory system development(GO:0048880)
0.6	1.7	GO:0021550	medulla oblongata development(GO:0021550)
0.5	5.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.5	1.5	GO:0033058	directional locomotion(GO:0033058)
0.4	1.3	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.4	1.3	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.4	3.9	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.4	0.4	GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
0.4	0.7	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3	1.0	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.3	1.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3	1.0	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
0.3	1.3	GO:0046959	habituation(GO:0046959)
0.3	4.1	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3	0.9	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.3	0.6	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.3	0.9	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3	1.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3	0.5	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.3	1.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.3	0.8	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.3	1.0	GO:2000821	regulation of grooming behavior(GO:2000821)
0.3	0.8	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.2	0.7	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.2	0.7	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.2	0.2	GO:1902473	regulation of protein localization to synapse(GO:1902473)
0.2	0.9	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.2	0.6	GO:0072205	metanephric collecting duct development(GO:0072205)
0.2	0.6	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2	2.0	GO:0097120	receptor localization to synapse(GO:0097120)
0.2	0.6	GO:0015817	histidine transport(GO:0015817)
0.2	0.6	GO:0010046	response to mycotoxin(GO:0010046)
0.2	1.2	GO:0015816	glycine transport(GO:0015816)
0.2	0.6	GO:0003150	muscular septum morphogenesis(GO:0003150)
0.2	1.6	GO:0071625	vocalization behavior(GO:0071625)
0.2	0.6	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	0.8	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	0.4	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.2	0.8	GO:0060155	platelet dense granule organization(GO:0060155)
0.2	0.2	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2	1.0	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.2	0.5	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2	0.5	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.2	0.5	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2	2.4	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2	0.6	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.2	0.5	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.2	0.5	GO:0001661	conditioned taste aversion(GO:0001661)
0.2	0.9	GO:0016198	axon choice point recognition(GO:0016198)
0.2	0.5	GO:0097503	sialylation(GO:0097503)
0.2	2.1	GO:0046549	retinal cone cell development(GO:0046549)
0.2	0.6	GO:0030035	microspike assembly(GO:0030035)
0.1	0.6	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.1	0.4	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.1	0.7	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.1	0.3	GO:2001197	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1	1.1	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	0.4	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	0.3	GO:0003162	atrioventricular node development(GO:0003162)
0.1	0.1	GO:0006533	aspartate catabolic process(GO:0006533)
0.1	0.4	GO:0007412	axon target recognition(GO:0007412)
0.1	0.5	GO:0023041	neuronal signal transduction(GO:0023041)
0.1	0.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.3	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.1	1.9	GO:0016486	peptide hormone processing(GO:0016486)
0.1	0.3	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	0.4	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.2	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.4	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.6	GO:0021637	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.1	0.2	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1	0.1	GO:0021553	olfactory nerve development(GO:0021553)
0.1	0.4	GO:0036394	amylase secretion(GO:0036394)
0.1	1.0	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.1	0.5	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1	0.5	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1	1.3	GO:0042428	serotonin metabolic process(GO:0042428)
0.1	0.1	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.1	0.3	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	1.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.4	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.8	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	1.1	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1	0.4	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.3	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.1	0.2	GO:0014719	skeletal muscle satellite cell activation(GO:0014719)
0.1	0.3	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.1	0.6	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.1	0.7	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1	0.3	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.3	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1	1.3	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	0.1	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
0.1	5.9	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	0.6	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1	0.2	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.1	0.3	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.5	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.1	0.4	GO:0086015	SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
0.1	0.3	GO:0042126	nitrate metabolic process(GO:0042126)
0.1	0.3	GO:0090135	actin filament branching(GO:0090135)
0.1	0.2	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	0.3	GO:0060279	positive regulation of ovulation(GO:0060279)
0.1	0.2	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1	0.4	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.4	GO:0061588	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1	0.2	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.1	0.3	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.1	0.2	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	1.5	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	0.3	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.1	0.1	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.9	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.2	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.4	GO:0060074	synapse maturation(GO:0060074)
0.1	0.4	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.1	GO:0021586	pons maturation(GO:0021586)
0.1	0.3	GO:0048664	neuron fate determination(GO:0048664)
0.1	0.9	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.1	0.4	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1	0.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.1	0.4	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.1	0.2	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1	0.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.1	0.2	GO:0046103	inosine biosynthetic process(GO:0046103)
0.1	0.2	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1	1.8	GO:0010107	potassium ion import(GO:0010107)
0.1	0.3	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.1	1.1	GO:0007019	microtubule depolymerization(GO:0007019)
0.1	0.6	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.2	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.1	0.2	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.1	0.3	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.4	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	0.3	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.5	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.4	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1	0.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.2	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.4	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1	0.5	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1	0.2	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.1	0.1	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.1	0.6	GO:0060292	long term synaptic depression(GO:0060292)
0.1	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.4	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.1	0.2	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1	1.3	GO:2001222	regulation of neuron migration(GO:2001222)
0.1	0.3	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.3	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.6	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.1	0.4	GO:0060539	diaphragm development(GO:0060539)
0.1	0.1	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1	0.4	GO:0001975	response to amphetamine(GO:0001975)
0.1	0.4	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.1	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1	0.2	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.3	GO:0006559	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.2	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.1	0.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.1	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.1	0.2	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1	0.2	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.1	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.1	0.1	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.1	0.5	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.2	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.1	GO:0060022	hard palate development(GO:0060022)
0.0	0.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.1	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	0.0	GO:1904468	negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0	0.1	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0	0.2	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.2	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.0	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.4	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.8	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.1	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
0.0	0.2	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.3	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.6	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.2	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:2001025	positive regulation of response to drug(GO:2001025)
0.0	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.2	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.1	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.4	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	1.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.7	GO:1901381	positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.0	0.2	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0061047	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.2	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0072553	terminal button organization(GO:0072553)
0.0	0.3	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.4	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.2	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.1	GO:1903596	regulation of gap junction assembly(GO:1903596)
0.0	3.4	GO:0007612	learning(GO:0007612)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.2	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.5	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.2	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0	0.2	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	1.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.4	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.7	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.6	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.0	0.8	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.2	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.7	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0034633	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.1	GO:0086019	cell-cell signaling involved in cardiac conduction(GO:0086019)
0.0	0.1	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.6	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	1.2	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.4	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0021590	cerebellum maturation(GO:0021590)
0.0	0.4	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	0.4	GO:0001967	suckling behavior(GO:0001967)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	1.2	GO:0051058	negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.1	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0	0.1	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.0	0.3	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.6	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0010535	positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.1	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
0.0	0.6	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.2	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.1	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.4	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.0	0.2	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.0	0.0	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0	0.0	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0	0.1	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.1	GO:0070350	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.7	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.2	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.4	GO:0022401	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0	0.2	GO:0003140	determination of left/right asymmetry in lateral mesoderm(GO:0003140)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.1	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.1	GO:0042711	maternal behavior(GO:0042711)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.0	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)
0.0	1.9	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.1	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.0	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.2	GO:0045357	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357)
0.0	0.3	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0009946	proximal/distal axis specification(GO:0009946)
0.0	0.1	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.0	0.0	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0	0.1	GO:0007632	visual behavior(GO:0007632)
0.0	0.2	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.1	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.2	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.0	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0	0.1	GO:1903059	regulation of protein lipidation(GO:1903059)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.3	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:0048242	epinephrine secretion(GO:0048242)
0.0	0.1	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.7	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.1	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.4	GO:0010829	negative regulation of glucose transport(GO:0010829)
0.0	0.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.3	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.0	GO:0071316	cellular response to nicotine(GO:0071316)
0.0	0.2	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:0010841	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0	0.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.0	GO:0044849	estrous cycle(GO:0044849)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.2	GO:0033574	response to testosterone(GO:0033574)
0.0	0.0	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:1990089	response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.4	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.0	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0072757	cellular response to camptothecin(GO:0072757)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0035902	response to immobilization stress(GO:0035902)
0.0	0.1	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.1	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.0	0.3	GO:0072337	modified amino acid transport(GO:0072337)
0.0	0.0	GO:0072174	metanephric tubule formation(GO:0072174)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.1	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.0	0.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.1	GO:0035989	tendon development(GO:0035989)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.0	GO:0021683	cerebellar granular layer morphogenesis(GO:0021683)
0.0	0.0	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.1	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.0	0.3	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.0	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.0	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.0	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.0	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.1	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.2	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.0	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.0	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.1	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.0	GO:2000347	positive regulation of hepatocyte proliferation(GO:2000347)
0.0	0.1	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.2	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.2	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.1	GO:0070417	cellular response to cold(GO:0070417)
0.0	0.0	GO:0042160	plasma lipoprotein particle oxidation(GO:0034441) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.0	GO:0090148	membrane fission(GO:0090148)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.0	GO:2000192	negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.3	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.0	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.2	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.6	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.0	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.0	0.0	GO:0033034	positive regulation of myeloid cell apoptotic process(GO:0033034)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.1	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0	0.0	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.0	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.1	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.2	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.0	GO:0031296	B cell costimulation(GO:0031296)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.0	GO:0042504	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.0	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	0.0	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.0	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.0	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.1	GO:0045581	negative regulation of T cell differentiation(GO:0045581)
0.0	0.0	GO:2000508	regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.1	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.0	GO:0035962	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0	0.2	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0	0.0	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.0	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.1	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.0	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.2	GO:0047496	vesicle transport along microtubule(GO:0047496)
0.0	0.1	GO:0032048	cardiolipin metabolic process(GO:0032048)
0.0	0.0	GO:1904398	positive regulation of postsynaptic membrane organization(GO:1901628) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398)
0.0	0.0	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	5.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.4	1.9	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.4	6.9	GO:0060077	inhibitory synapse(GO:0060077)
0.4	1.8	GO:0044326	dendritic spine neck(GO:0044326)
0.3	3.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	1.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	1.7	GO:0042788	polysomal ribosome(GO:0042788)
0.2	0.6	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.2	0.7	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2	0.7	GO:0044308	axonal spine(GO:0044308)
0.2	1.9	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	0.5	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.4	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.1	1.5	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.3	GO:0044393	microspike(GO:0044393)
0.1	1.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.4	GO:0072534	perineuronal net(GO:0072534)
0.1	0.5	GO:0061574	ASAP complex(GO:0061574)
0.1	1.1	GO:0005883	neurofilament(GO:0005883)
0.1	0.5	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.7	GO:0030673	axolemma(GO:0030673)
0.1	0.7	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.3	GO:0043511	inhibin complex(GO:0043511)
0.1	0.3	GO:1990635	proximal dendrite(GO:1990635)
0.1	0.6	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1	4.6	GO:0043198	dendritic shaft(GO:0043198)
0.1	2.2	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.3	GO:0032437	cuticular plate(GO:0032437)
0.1	3.3	GO:0042734	presynaptic membrane(GO:0042734)
0.1	1.0	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1	1.0	GO:0071565	nBAF complex(GO:0071565)
0.1	0.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.3	GO:0045298	tubulin complex(GO:0045298)
0.1	0.5	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	0.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.2	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.7	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	0.3	GO:0097433	dense body(GO:0097433)
0.1	1.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.6	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.5	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.7	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	1.4	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	0.2	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.0	GO:1990812	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0043196	varicosity(GO:0043196)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.5	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.5	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:1990716	axonemal central apparatus(GO:1990716)
0.0	0.3	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	1.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.0	GO:0031941	filamentous actin(GO:0031941)
0.0	0.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	1.4	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0098553	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	5.0	GO:0097060	synaptic membrane(GO:0097060)
0.0	0.2	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	1.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.9	GO:0030315	T-tubule(GO:0030315)
0.0	0.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	2.2	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.1	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.5	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.4	GO:0097228	sperm principal piece(GO:0097228)
0.0	1.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.4	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.0	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.6	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	1.1	GO:0043195	terminal bouton(GO:0043195)
0.0	0.3	GO:0031011	Ino80 complex(GO:0031011)
0.0	0.1	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	1.3	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.5	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.0	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	1.6	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	4.2	GO:0043025	neuronal cell body(GO:0043025)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.0	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.0	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	2.1	GO:0045202	synapse(GO:0045202)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.0	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.4	GO:0030018	Z disc(GO:0030018)
0.0	0.7	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.0	GO:1990696	USH2 complex(GO:1990696)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.0	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0034706	sodium channel complex(GO:0034706)
0.0	2.5	GO:0043005	neuron projection(GO:0043005)
0.0	0.0	GO:0097452	GAIT complex(GO:0097452)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.8	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.5	3.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.5	1.5	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.4	1.3	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.4	3.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.4	1.8	GO:0004985	opioid receptor activity(GO:0004985)
0.4	5.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.3	1.0	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.3	0.6	GO:0045503	dynein light chain binding(GO:0045503)
0.3	1.2	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.3	1.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3	0.8	GO:0050816	phosphothreonine binding(GO:0050816)
0.2	0.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.2	1.4	GO:0033265	choline binding(GO:0033265)
0.2	0.7	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.2	0.9	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2	2.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2	0.7	GO:0035939	microsatellite binding(GO:0035939)
0.2	0.8	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.2	0.4	GO:0097109	neuroligin family protein binding(GO:0097109)
0.2	0.6	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.2	0.6	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2	0.8	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.2	1.5	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.2	0.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2	0.5	GO:0055100	adiponectin binding(GO:0055100)
0.2	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.2	1.2	GO:0003680	AT DNA binding(GO:0003680)
0.2	0.5	GO:0051373	FATZ binding(GO:0051373)
0.1	0.6	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
0.1	0.7	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.4	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1	0.4	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	1.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.7	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.5	GO:0031433	telethonin binding(GO:0031433)
0.1	0.6	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1	0.6	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.4	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	1.5	GO:0031005	filamin binding(GO:0031005)
0.1	1.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	1.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.5	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.3	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	2.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	1.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.4	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.5	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.8	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	2.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.8	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.7	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	0.9	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.3	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	2.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.1	1.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.4	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.4	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	1.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	1.4	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	1.6	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.4	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	0.3	GO:0004977	melanocortin receptor activity(GO:0004977)
0.1	0.2	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	1.1	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.1	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1	0.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.3	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.1	0.4	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.3	GO:0070728	leucine binding(GO:0070728)
0.1	0.1	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.1	0.1	GO:0030172	troponin C binding(GO:0030172)
0.1	0.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.9	GO:0004890	GABA-A receptor activity(GO:0004890)
0.1	0.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	1.5	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	1.3	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.1	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	1.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	1.0	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.1	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	1.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0003933	GTP cyclohydrolase activity(GO:0003933)
0.0	0.7	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.8	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	1.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.5	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	1.0	GO:0030552	cAMP binding(GO:0030552)
0.0	0.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.3	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.3	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.7	GO:0005112	Notch binding(GO:0005112)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.3	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.2	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.6	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004337	geranyltranstransferase activity(GO:0004337)
0.0	0.1	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.5	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.7	GO:0022839	ion gated channel activity(GO:0022839)
0.0	0.5	GO:0031489	myosin V binding(GO:0031489)
0.0	0.3	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.8	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.2	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.5	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.3	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.2	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.3	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.6	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.4	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.2	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	1.2	GO:0051087	chaperone binding(GO:0051087)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	2.7	GO:0008017	microtubule binding(GO:0008017)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.0	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.0	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.0	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.0	GO:0042731	PH domain binding(GO:0042731)
0.0	0.0	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	1.9	GO:0003729	mRNA binding(GO:0003729)
0.0	0.0	GO:0016595	glutamate binding(GO:0016595)
0.0	0.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.3	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.1	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.0	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0080084	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.0	GO:0043842	Kdo transferase activity(GO:0043842)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.4	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.0	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.0	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.0	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0008147	structural constituent of bone(GO:0008147)
0.0	0.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.0	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	0.6	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	1.5	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.4	PID NOTCH PATHWAY	Notch signaling pathway
0.0	1.2	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	1.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.8	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.9	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	2.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3	4.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2	2.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	4.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.2	2.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	3.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	1.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	0.3	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	1.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	0.9	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	2.3	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.1	0.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	0.5	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	1.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.7	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.8	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	0.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.0	0.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.9	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.1	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.0	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.0	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.1	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME SIGNALLING TO ERKS	Genes involved in Signalling to ERKs
0.0	0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.0	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.0	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand

Results for Smad2

Z-value: 1.08

Motif logo

Transcription factors associated with Smad2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Smad2 motif across conditions

Conditions sorted by the z-value of the Smad2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Smad2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: