CRE | Gene | Distance | Association probability | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|---|---|
chr9_99869828_99871174 | Sox14 | 5154 | 0.207846 | 0.38 | 3.1e-03 | Click! |
chr9_99871221_99872842 | Sox14 | 3624 | 0.232622 | 0.55 | 4.3e-06 | Click! |
chr9_99872892_99873043 | Sox14 | 2688 | 0.268492 | 0.43 | 5.6e-04 | Click! |
chr9_99873057_99873527 | Sox14 | 2363 | 0.289993 | 0.69 | 1.5e-09 | Click! |
chr9_99873689_99874102 | Sox14 | 1760 | 0.356365 | 0.55 | 4.3e-06 | Click! |
Cis Regulatory Element (CRE) | Target Score | Top associated gene | Gene Info | Distance of CRE to TSS | CRE/Gene association probability |
---|---|---|---|---|---|
chr10_81229656_81230911 | 31.25 |
Atcay |
ataxia, cerebellar, Cayman type |
502 |
0.53 |
chr8_70119024_70120981 | 30.41 |
Ncan |
neurocan |
871 |
0.35 |
chr3_34652462_34653573 | 24.96 |
Sox2 |
SRY (sex determining region Y)-box 2 |
2612 |
0.16 |
chr8_123413418_123414506 | 24.89 |
Tubb3 |
tubulin, beta 3 class III |
2372 |
0.11 |
chr13_20473087_20474265 | 24.15 |
Gm32036 |
predicted gene, 32036 |
186 |
0.89 |
chr2_6883618_6884699 | 23.27 |
Gm13389 |
predicted gene 13389 |
112 |
0.85 |
chr1_66386919_66387899 | 22.79 |
Map2 |
microtubule-associated protein 2 |
398 |
0.87 |
chr16_16558986_16560577 | 21.78 |
Fgd4 |
FYVE, RhoGEF and PH domain containing 4 |
209 |
0.94 |
chr8_94995272_94995731 | 20.64 |
Adgrg1 |
adhesion G protein-coupled receptor G1 |
160 |
0.93 |
chr5_19907724_19909563 | 20.08 |
Magi2 |
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
682 |
0.82 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 65.2 | GO:0007612 | learning(GO:0007612) |
7.4 | 59.2 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
1.6 | 58.7 | GO:0021954 | central nervous system neuron development(GO:0021954) |
1.2 | 55.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.8 | 52.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
2.1 | 49.5 | GO:0001964 | startle response(GO:0001964) |
15.4 | 46.1 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
1.3 | 41.6 | GO:0007019 | microtubule depolymerization(GO:0007019) |
2.3 | 38.8 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
3.7 | 36.6 | GO:0097120 | receptor localization to synapse(GO:0097120) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 121.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
1.6 | 72.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.3 | 65.4 | GO:0030424 | axon(GO:0030424) |
1.9 | 58.9 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
2.0 | 53.7 | GO:0044295 | axonal growth cone(GO:0044295) |
0.6 | 49.6 | GO:0043204 | perikaryon(GO:0043204) |
0.2 | 45.9 | GO:0043005 | neuron projection(GO:0043005) |
2.1 | 40.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
12.4 | 37.3 | GO:0097451 | glial limiting end-foot(GO:0097451) |
1.1 | 36.4 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
18.7 | 56.1 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.2 | 47.1 | GO:0015631 | tubulin binding(GO:0015631) |
9.1 | 45.3 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.1 | 38.4 | GO:0005509 | calcium ion binding(GO:0005509) |
0.2 | 36.6 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
2.8 | 33.1 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
4.6 | 32.2 | GO:0003680 | AT DNA binding(GO:0003680) |
10.7 | 32.0 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
0.5 | 30.3 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
1.3 | 29.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 40.5 | PID LKB1 PATHWAY | LKB1 signaling events |
0.6 | 35.8 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
1.2 | 31.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
1.0 | 27.7 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.6 | 26.7 | PID NOTCH PATHWAY | Notch signaling pathway |
0.8 | 24.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.7 | 24.1 | PID AURORA B PATHWAY | Aurora B signaling |
0.5 | 22.4 | PID CDC42 PATHWAY | CDC42 signaling events |
1.2 | 19.0 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.8 | 17.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 52.4 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
3.4 | 47.5 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
2.3 | 35.0 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.7 | 31.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.2 | 31.4 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
2.3 | 29.7 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
1.9 | 29.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
1.3 | 29.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
1.5 | 26.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
1.4 | 24.5 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |