CRE | Gene | Distance | Association probability | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|---|---|
chr3_34647222_34647420 | Sox2 | 3084 | 0.144562 | 0.24 | 6.3e-02 | Click! |
chr3_34648019_34648437 | Sox2 | 2177 | 0.183947 | 0.61 | 1.8e-07 | Click! |
chr3_34648572_34651394 | Sox2 | 422 | 0.731272 | 0.78 | 2.1e-13 | Click! |
chr3_34651759_34652037 | Sox2 | 1493 | 0.256133 | 0.73 | 4.3e-11 | Click! |
chr3_34652462_34653573 | Sox2 | 2612 | 0.156553 | 0.75 | 6.0e-12 | Click! |
Cis Regulatory Element (CRE) | Target Score | Top associated gene | Gene Info | Distance of CRE to TSS | CRE/Gene association probability |
---|---|---|---|---|---|
chr10_29143400_29144848 | 43.14 |
Soga3 |
SOGA family member 3 |
65 |
0.5 |
chrX_143930842_143933141 | 29.93 |
Dcx |
doublecortin |
1059 |
0.64 |
chr8_70119024_70120981 | 28.55 |
Ncan |
neurocan |
871 |
0.35 |
chr9_52148115_52149635 | 26.61 |
Zc3h12c |
zinc finger CCCH type containing 12C |
19236 |
0.18 |
chr8_123410787_123412789 | 21.43 |
Tubb3 |
tubulin, beta 3 class III |
198 |
0.84 |
chr8_123413418_123414506 | 21.24 |
Tubb3 |
tubulin, beta 3 class III |
2372 |
0.11 |
chr5_88583963_88584847 | 20.79 |
Rufy3 |
RUN and FYVE domain containing 3 |
611 |
0.7 |
chr2_6883618_6884699 | 20.72 |
Gm13389 |
predicted gene 13389 |
112 |
0.85 |
chr13_20473087_20474265 | 20.23 |
Gm32036 |
predicted gene, 32036 |
186 |
0.89 |
chr13_34126566_34127191 | 19.41 |
Tubb2b |
tubulin, beta 2B class IIB |
3476 |
0.13 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 148.5 | GO:0097485 | neuron projection guidance(GO:0097485) |
3.5 | 76.0 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
8.3 | 74.3 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
1.4 | 71.9 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
4.7 | 56.1 | GO:0071625 | vocalization behavior(GO:0071625) |
0.9 | 56.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
1.4 | 51.1 | GO:0021954 | central nervous system neuron development(GO:0021954) |
3.0 | 47.2 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
4.1 | 45.0 | GO:0097120 | receptor localization to synapse(GO:0097120) |
10.9 | 32.6 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 148.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
3.0 | 83.7 | GO:0044295 | axonal growth cone(GO:0044295) |
0.3 | 68.5 | GO:0030425 | dendrite(GO:0030425) |
1.6 | 58.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
1.3 | 53.2 | GO:0042734 | presynaptic membrane(GO:0042734) |
1.6 | 50.6 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.7 | 50.5 | GO:0043204 | perikaryon(GO:0043204) |
1.7 | 49.9 | GO:0031941 | filamentous actin(GO:0031941) |
4.1 | 49.1 | GO:0043194 | axon initial segment(GO:0043194) |
0.6 | 48.0 | GO:0030426 | growth cone(GO:0030426) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 88.4 | GO:0015631 | tubulin binding(GO:0015631) |
11.5 | 57.7 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
17.8 | 53.4 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 51.8 | GO:0005509 | calcium ion binding(GO:0005509) |
0.2 | 43.6 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
3.1 | 43.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
1.8 | 41.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
3.0 | 38.6 | GO:0031005 | filamin binding(GO:0031005) |
2.9 | 34.6 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.9 | 33.2 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 51.6 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.3 | 43.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.6 | 42.2 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
1.1 | 31.1 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
1.1 | 25.2 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
0.7 | 25.2 | PID LKB1 PATHWAY | LKB1 signaling events |
0.2 | 24.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
1.0 | 24.0 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.8 | 23.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.7 | 22.9 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.2 | 72.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
2.5 | 65.8 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
1.3 | 37.7 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
0.3 | 35.0 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
0.8 | 34.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
2.1 | 34.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
2.2 | 32.3 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
1.5 | 28.8 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
1.4 | 28.6 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
1.7 | 28.1 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |